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WO2002008414A1 - Novel nucleic acid probes and method of assaying nucleic acid by using the same - Google Patents

Novel nucleic acid probes and method of assaying nucleic acid by using the same Download PDF

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Publication number
WO2002008414A1
WO2002008414A1 PCT/IB2001/001147 IB0101147W WO0208414A1 WO 2002008414 A1 WO2002008414 A1 WO 2002008414A1 IB 0101147 W IB0101147 W IB 0101147W WO 0208414 A1 WO0208414 A1 WO 0208414A1
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
hybridization
same
assaying
fluorescent substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2001/001147
Other languages
English (en)
French (fr)
Inventor
Ryuichiro Kurane
Takahiro Kanagawa
Yoichi Kamagata
Masaki Torimura
Shinya Kurata
Kazutaka Yamada
Toyokazu Yokomaku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Advanced Industrial Science and Technology AIST
Kankyo Engineering Co Ltd
Original Assignee
National Institute of Advanced Industrial Science and Technology AIST
Kankyo Engineering Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2000193133A external-priority patent/JP3965872B2/ja
Application filed by National Institute of Advanced Industrial Science and Technology AIST, Kankyo Engineering Co Ltd filed Critical National Institute of Advanced Industrial Science and Technology AIST
Priority to DE60140804T priority Critical patent/DE60140804D1/de
Priority to CA002383939A priority patent/CA2383939C/en
Priority to EP01953279A priority patent/EP1295941B1/en
Publication of WO2002008414A1 publication Critical patent/WO2002008414A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PCT/IB2001/001147 2000-06-27 2001-06-27 Novel nucleic acid probes and method of assaying nucleic acid by using the same Ceased WO2002008414A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE60140804T DE60140804D1 (de) 2000-06-27 2001-06-27 Neue nukleinsäuresonden und verfahren zum testen von nukleinsäuren unter deren verwendung
CA002383939A CA2383939C (en) 2000-06-27 2001-06-27 Novel nucleic acid probes, method for determining nucleic acids by using the probes, and method for analyzing data obtained by the method
EP01953279A EP1295941B1 (en) 2000-06-27 2001-06-27 Novel nucleic acid probes and method of assaying nucleic acid by using the same

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2000193133A JP3965872B2 (ja) 2000-06-27 2000-06-27 新規な定量的多型解析方法
JP2000-193133 2000-06-27
JP2000-236115 2000-08-03
JP2000236115 2000-08-03
JP2000292483 2000-09-26
JP2000-292483 2000-09-26

Publications (1)

Publication Number Publication Date
WO2002008414A1 true WO2002008414A1 (en) 2002-01-31

Family

ID=27343862

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2001/001147 Ceased WO2002008414A1 (en) 2000-06-27 2001-06-27 Novel nucleic acid probes and method of assaying nucleic acid by using the same

Country Status (5)

Country Link
US (1) US7354707B2 (ja)
EP (1) EP1295941B1 (ja)
CA (1) CA2383939C (ja)
DE (1) DE60140804D1 (ja)
WO (1) WO2002008414A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1358346A2 (en) * 2000-03-07 2003-11-05 E.I. Dupont De Nemours And Company Real time quantitative pcr with intercalating dye for single and multiplex target dna
WO2003102179A1 (en) * 2002-05-31 2003-12-11 Kankyo Engineering Co., Ltd. Novel method of assyaing nucleic acid using labeled nucleotide
WO2010013317A1 (ja) * 2008-07-30 2010-02-04 株式会社Ｊ－Ｂｉｏ２１ 核酸プローブセットおよびその使用方法
US8346485B2 (en) 2008-11-25 2013-01-01 Quest Diagnostics Investments Incorporated Methods and apparatuses for estimating initial target nucleic acid concentration in a sample by modeling background signal and cycle-dependent amplification efficiency of a polymerase chain reaction

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CA2424614A1 (en) * 2001-03-27 2003-04-02 Kankyo Engineering Co., Ltd. Novel nucleic acid probe and novel method of assaying nucleic acids using the same
CN100439515C (zh) * 2003-03-03 2008-12-03 清华大学 一种核酸分析芯片实验室系统与应用
JP2006522329A (ja) 2003-03-07 2006-09-28 ラクセル・バイオサイエンシズ・リミテッド 酸素感受性プローブ
ATE513059T1 (de) * 2003-04-16 2011-07-15 Arkray Inc Verfahren zum nachweis oder zur quantitativen bestimmung der mitochondrialen dna-variation 3243 und kit dafür
JP4454249B2 (ja) * 2003-04-18 2010-04-21 アークレイ株式会社 膵ラ氏島アミロイドタンパク質変異遺伝子の検出法ならびにそのための核酸プローブおよびキット
WO2004111602A2 (en) * 2003-05-16 2004-12-23 University Of Rochester Colorimetric and fluorescent methods for sensing of oligonucleotides
EP1625232B1 (en) * 2003-05-16 2013-09-04 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Internal control nucleic acid molecule for nucleic acid amplification systems
CN1280428C (zh) * 2003-05-19 2006-10-18 清华大学 一种基于微小颗粒的生物芯片系统及其应用
EP1716252A1 (en) * 2004-02-19 2006-11-02 University College Cork-National University of Ireland, Cork Detection of biologically active compounds
US20060057611A1 (en) * 2004-06-30 2006-03-16 Applera Corporation Log-linear amplification
US20060110724A1 (en) 2004-11-19 2006-05-25 Burkhardt William Iii Quantitative real-time assay for noroviruses and enteroviruses with built in quality control standard
AU2006215038B2 (en) * 2005-02-18 2011-07-07 Kyushu University, National University Corporation Gene detection method
US8008066B2 (en) 2005-03-10 2011-08-30 Gen-Probe Incorporated System for performing multi-formatted assays
JP4789518B2 (ja) * 2005-06-30 2011-10-12 キヤノン株式会社 製造条件付きプローブ固定担体を用いた標的物質の検出方法ならびにそのための装置、キット及びシステム
US11001881B2 (en) 2006-08-24 2021-05-11 California Institute Of Technology Methods for detecting analytes
US8637436B2 (en) 2006-08-24 2014-01-28 California Institute Of Technology Integrated semiconductor bioarray
EP2029775B1 (en) 2006-06-05 2014-10-15 California Institute Of Technology Real time micro arrays
US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
US8048626B2 (en) 2006-07-28 2011-11-01 California Institute Of Technology Multiplex Q-PCR arrays
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
US20100075312A1 (en) * 2006-09-28 2010-03-25 Stokes Bio Limited Qpcr analysis apparatus
US20090269756A1 (en) * 2006-11-30 2009-10-29 Arkray, Inc. Primer set for amplifying cyp2c19 gene, reagent for amplifying cyp2c19 gene containing the same, and the uses thereof
WO2008066161A1 (en) * 2006-11-30 2008-06-05 Arkray, Inc. Primer set for amplification of nat2 gene, reagent for amplification of nat2 gene comprising the same, and use of the same
CN101501496B (zh) * 2007-01-10 2013-05-15 爱科来株式会社 光学检测装置的性能确认方法及其使用的标准试剂
US20100129796A1 (en) * 2008-11-24 2010-05-27 Micah Halpern Dye probe fluorescence resonance energy transfer genotyping
WO2010135916A1 (zh) * 2009-05-26 2010-12-02 厦门大学 一种单管检测多个单核苷酸变异或单核苷酸多态性的方法
WO2011011535A2 (en) * 2009-07-21 2011-01-27 Gen-Probe Incorporated Methods and compositions for quantitative detection of nucleic acid sequences over an extended dynamic range
KR101472940B1 (ko) 2009-10-30 2014-12-24 아크레이 가부시키가이샤 Ｅｇｆｒ 유전자 다형 검출용 프로브 및 그 용도
KR101982126B1 (ko) 2010-03-08 2019-05-27 몬산토 테크놀로지 엘엘씨 식물에서 유전자 조절을 위한 폴리뉴클레오타이드 분자
CN102268476B (zh) 2010-06-01 2014-02-19 爱科来株式会社 Vkorc1基因的第-1639位碱基的多态性检测方法、以及用于该方法的核酸探针和试剂盒
JP5940771B2 (ja) 2010-07-12 2016-06-29 アークレイ株式会社 ａｂｌ遺伝子多型の検出用プローブおよびその用途
US9046507B2 (en) 2010-07-29 2015-06-02 Gen-Probe Incorporated Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure
AU2012222178B2 (en) 2011-02-24 2014-12-18 Gen-Probe Incorporated Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector
US9045799B2 (en) 2011-03-09 2015-06-02 Arkray, Inc. Probe for detecting polymorphism in CYP3A gene, method of detecting polymorphism, method of evaluating drug efficacy, and reagent kit for detecting polymorphism
KR101660322B1 (ko) 2011-04-28 2016-09-29 아크레이 가부시키가이샤 ＮＰＭ1 유전자의 ｅｘｏｎ12 변이의 검출용 프로브 및 그 용도
JP5757908B2 (ja) 2011-05-02 2015-08-05 アークレイ株式会社 多型検出用プローブ、多型検出方法、薬効評価方法、疾患予測方法及び多型検出用試薬キット
MX377067B (es) * 2011-09-13 2025-03-07 Monsanto Technology Llc Métodos y composiciones para el control de malezas.
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US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
JP2013074888A (ja) 2011-09-15 2013-04-25 Arkray Inc ＩＬ２８Ｂ（ｒｓ８０９９９１７）とＩＴＰＡ（ｒｓ１１２７３５４）の変異を検出する方法
JP2013081450A (ja) * 2011-09-27 2013-05-09 Arkray Inc 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用試薬キット
WO2013175480A1 (en) 2012-05-24 2013-11-28 A.B. Seeds Ltd. Compositions and methods for silencing gene expression
EP2698436A1 (en) * 2012-08-14 2014-02-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Colorectal cancer markers
JP5928906B2 (ja) 2013-08-27 2016-06-01 横河電機株式会社 核酸配列計測方法、核酸配列計測用デバイス、核酸配列計測用デバイスの製造方法および核酸配列計測装置
GB201319180D0 (en) * 2013-10-30 2013-12-11 Mast Group Ltd Nucleic acid probe
RU2694950C2 (ru) 2013-11-04 2019-07-18 Монсанто Текнолоджи Ллс Композиции и способы для борьбы с членистоногими паразитами и заражениями вредителями
US11807857B2 (en) 2014-06-25 2023-11-07 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
BR112017015705A2 (pt) 2015-01-22 2018-03-20 Monsanto Technology Llc composições e métodos para controle de leptinotarsa
US9708647B2 (en) 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
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DK3305912T3 (da) * 2015-06-04 2021-12-06 Mizuho Medy Co Ltd Kit til samtidig detektion af multiple målnukleinsyrer, som er forskellige fra hinanden, og detektionsfremgangsmåde med anvendelse deraf
US9499861B1 (en) 2015-09-10 2016-11-22 Insilixa, Inc. Methods and systems for multiplex quantitative nucleic acid amplification
JP6611206B2 (ja) 2016-02-09 2019-11-27 栄研化学株式会社 標的核酸を検出する方法およびそれに用いる核酸プローブ
WO2017155858A1 (en) 2016-03-07 2017-09-14 Insilixa, Inc. Nucleic acid sequence identification using solid-phase cyclic single base extension
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CN114958981B (zh) * 2021-02-19 2025-11-11 壹宏(深圳)基因有限公司 一种通过灰度值计算微生物单元数浓度的方法

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1358346A2 (en) * 2000-03-07 2003-11-05 E.I. Dupont De Nemours And Company Real time quantitative pcr with intercalating dye for single and multiplex target dna
WO2003102179A1 (en) * 2002-05-31 2003-12-11 Kankyo Engineering Co., Ltd. Novel method of assyaing nucleic acid using labeled nucleotide
WO2010013317A1 (ja) * 2008-07-30 2010-02-04 株式会社Ｊ－Ｂｉｏ２１ 核酸プローブセットおよびその使用方法
US8346485B2 (en) 2008-11-25 2013-01-01 Quest Diagnostics Investments Incorporated Methods and apparatuses for estimating initial target nucleic acid concentration in a sample by modeling background signal and cycle-dependent amplification efficiency of a polymerase chain reaction

Also Published As

Publication number Publication date
DE60140804D1 (de) 2010-01-28
US7354707B2 (en) 2008-04-08
CA2383939A1 (en) 2002-01-31
EP1295941A1 (en) 2003-03-26
CA2383939C (en) 2009-12-01
EP1295941A4 (en) 2004-06-16
US20020106653A1 (en) 2002-08-08
EP1295941B1 (en) 2009-12-16

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