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WO2002008283A3 - Lp120 polypeptides and therapeutic uses thereof - Google Patents

Lp120 polypeptides and therapeutic uses thereof Download PDF

Info

Publication number
WO2002008283A3
WO2002008283A3 PCT/US2001/016521 US0116521W WO0208283A3 WO 2002008283 A3 WO2002008283 A3 WO 2002008283A3 US 0116521 W US0116521 W US 0116521W WO 0208283 A3 WO0208283 A3 WO 0208283A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
therapeutic uses
relates
present
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/016521
Other languages
French (fr)
Other versions
WO2002008283A2 (en
Inventor
Margret Barbara Basinski
Dong-Jing Fu
Bradley Jay Mills
Paul Robert Rosteck Jr
Patanjali Raghavac Sankhavaram
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Priority to AU2001272919A priority Critical patent/AU2001272919A1/en
Publication of WO2002008283A2 publication Critical patent/WO2002008283A2/en
Publication of WO2002008283A3 publication Critical patent/WO2002008283A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to the identification and isolation of novel DNA, therapeutic uses and the recombinant production of novel polypeptides cloned from a normalized human bone marrow cDNA library, designated herein as LP120 polypeptides. The present invention also relates to vectors, host cells, and antibodies directed to LP120 polypeptides.
PCT/US2001/016521 2000-07-20 2001-07-10 Lp120 polypeptides and therapeutic uses thereof Ceased WO2002008283A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001272919A AU2001272919A1 (en) 2000-07-20 2001-07-10 Lp120 polypeptides and therapeutic uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21958400P 2000-07-20 2000-07-20
US60/219,584 2000-07-20

Publications (2)

Publication Number Publication Date
WO2002008283A2 WO2002008283A2 (en) 2002-01-31
WO2002008283A3 true WO2002008283A3 (en) 2003-01-09

Family

ID=22819871

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016521 Ceased WO2002008283A2 (en) 2000-07-20 2001-07-10 Lp120 polypeptides and therapeutic uses thereof

Country Status (2)

Country Link
AU (1) AU2001272919A1 (en)
WO (1) WO2002008283A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000004140A1 (en) * 1998-07-15 2000-01-27 Human Genome Sciences, Inc. 71 human secreted proteins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000004140A1 (en) * 1998-07-15 2000-01-27 Human Genome Sciences, Inc. 71 human secreted proteins

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BAGGIOLINI M ET AL: "HUMAN CHEMOKINES: AN UPDATE", ANNUAL REVIEW OF IMMUNOLOGY, ANNUAL REVIEWS INC, US, vol. 15, 1997, pages 675 - 705, XP002055737, ISSN: 0732-0582 *
DATABASE EMBL [online] 14 April 2000 (2000-04-14), BIRREN B., ET AL.: "Homo sapiens chromosome 17 clone RP11-380J4 map 17, WORKING DRAFT SEQUENCE,38 unordered pieces.", XP002210376, Database accession no. AC044879 *
HOWARD O M Z ET AL: "Chemokines: progress toward identifying molecular targets for therapeutic agents", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 14, no. 2, 1 February 1996 (1996-02-01), pages 46 - 51, XP004035816, ISSN: 0167-7799 *
LOCATI M ET AL: "CHEMOKINES AND CHEMOKINE RECEPTORS: BIOLOGY AND CLINICAL RELEVANCE IN INFLAMMATION AND AIDS", ANNUAL REVIEW OF MEDICINE: SELECTED TOPICS IN THE CLINICAL SCIENCES, ANNUAL REVIEWS INC., PALO ALTO, CA, US, vol. 50, 1999, pages 425 - 440, XP000915015, ISSN: 0066-4219 *

Also Published As

Publication number Publication date
WO2002008283A2 (en) 2002-01-31
AU2001272919A1 (en) 2002-02-05

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