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WO2002002599A3 - HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR17, AND USES THEROF - Google Patents

HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR17, AND USES THEROF Download PDF

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Publication number
WO2002002599A3
WO2002002599A3 PCT/EP2001/007532 EP0107532W WO0202599A3 WO 2002002599 A3 WO2002002599 A3 WO 2002002599A3 EP 0107532 W EP0107532 W EP 0107532W WO 0202599 A3 WO0202599 A3 WO 0202599A3
Authority
WO
WIPO (PCT)
Prior art keywords
igpcr17
protein
coupled receptor
receptor
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/007532
Other languages
French (fr)
Other versions
WO2002002599A2 (en
Inventor
Frank Wattler
Sigrid Wattler
Paul Trommler
Michael C Nehls
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ingenium Pharmaceuticals GmbH
Original Assignee
Ingenium Pharmaceuticals GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ingenium Pharmaceuticals GmbH filed Critical Ingenium Pharmaceuticals GmbH
Priority to AU2001281933A priority Critical patent/AU2001281933A1/en
Publication of WO2002002599A2 publication Critical patent/WO2002002599A2/en
Publication of WO2002002599A3 publication Critical patent/WO2002002599A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A novel human G protein-coupled receptor (GPcR) protein, IGPcR17, is identified and characterized. IGPcR17-encoding nucleotides, IGPcR17 proteins and fusion proteins, antibodies to the receptor, host cell expression systems, animal models in which the IGPcR17 gene is mutated, recombinant knock-out animals that do not express IGPcR17 and transgenic animals that express an IGPcR17 transgene are encompassed by the invention, as are compounds that modulate gene expression or receptor activity of IGPcR17 and their use for drug screening, and diagnosis or treatment of diseases, particularly central nervous system disorders.
PCT/EP2001/007532 2000-06-30 2001-07-02 HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR17, AND USES THEROF Ceased WO2002002599A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001281933A AU2001281933A1 (en) 2000-06-30 2001-07-02 Human g protein-coupled receptor igpcr17, and uses therof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21575900P 2000-06-30 2000-06-30
US60/215,759 2000-06-30

Publications (2)

Publication Number Publication Date
WO2002002599A2 WO2002002599A2 (en) 2002-01-10
WO2002002599A3 true WO2002002599A3 (en) 2002-10-10

Family

ID=22804265

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007532 Ceased WO2002002599A2 (en) 2000-06-30 2001-07-02 HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR17, AND USES THEROF

Country Status (2)

Country Link
AU (1) AU2001281933A1 (en)
WO (1) WO2002002599A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1240350A4 (en) 1999-12-23 2003-11-19 Millennium Pharm Inc P2y12 receptor
CA2501946C (en) 2002-10-16 2014-12-23 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
US7927840B2 (en) 2006-09-11 2011-04-19 Gen Probe Incorporated Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050549A2 (en) * 1997-05-07 1998-11-12 Human Genome Sciences, Inc. Two human g-protein coupled receptors: ebv-induced gpcr 2 (ebi-2) and edg-1-like gpcr
WO2000022131A2 (en) * 1998-10-13 2000-04-20 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human g protein-coupled receptors
WO2000028028A1 (en) * 1998-11-06 2000-05-18 Millennium Pharmaceuticals, Inc. G-protein coupled receptors, homologous to ebv-induced gpcr 2 (ebi-2). methods to seek for ligands thereof
WO2000031258A2 (en) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Human orphan g protein-coupled receptors
WO2000034333A1 (en) * 1998-12-10 2000-06-15 Astrazeneca Ab Novel g protein-coupled receptor
WO2001046454A1 (en) * 1999-12-23 2001-06-28 Cor Therapeutics, Inc. P2y12 receptor
WO2001057190A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2001085791A1 (en) * 2000-05-11 2001-11-15 Lifespan Biosciences, Inc. Nucleic acid sequences for novel gpcrs
WO2001098508A2 (en) * 2000-06-21 2001-12-27 Deltagen, Inc. Transgenic mice containing targeted gene disruptions
WO2002024942A2 (en) * 2000-09-20 2002-03-28 The Regents Of The University Of California Adp-glucose receptor

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050549A2 (en) * 1997-05-07 1998-11-12 Human Genome Sciences, Inc. Two human g-protein coupled receptors: ebv-induced gpcr 2 (ebi-2) and edg-1-like gpcr
WO2000022131A2 (en) * 1998-10-13 2000-04-20 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human g protein-coupled receptors
WO2000028028A1 (en) * 1998-11-06 2000-05-18 Millennium Pharmaceuticals, Inc. G-protein coupled receptors, homologous to ebv-induced gpcr 2 (ebi-2). methods to seek for ligands thereof
WO2000031258A2 (en) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Human orphan g protein-coupled receptors
WO2000034333A1 (en) * 1998-12-10 2000-06-15 Astrazeneca Ab Novel g protein-coupled receptor
WO2001046454A1 (en) * 1999-12-23 2001-06-28 Cor Therapeutics, Inc. P2y12 receptor
WO2001057190A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2001085791A1 (en) * 2000-05-11 2001-11-15 Lifespan Biosciences, Inc. Nucleic acid sequences for novel gpcrs
WO2001098508A2 (en) * 2000-06-21 2001-12-27 Deltagen, Inc. Transgenic mice containing targeted gene disruptions
WO2002024942A2 (en) * 2000-09-20 2002-03-28 The Regents Of The University Of California Adp-glucose receptor

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 14 June 2001 (2001-06-14), TAKASAKI J. ET AL.: "Homo sapiens mRNA for Gi-coupled ADP receptor HORK3", XP002208266, Database accession no. AB052684 *
DATABASE EMBL 6 March 2000 (2000-03-06), MUZNY D. ET AL.: "Homo sapiens 3 BAC RP11-25K24", XP002208265, Database accession no. AC024886 *
DATABASE EMBL 6 November 2001 (2001-11-06), TANG Y. ET AL.: "Human polynucleotide SEQ ID NO: 927", XP002208267, Database accession no. AAK52382 *
DATABASE EMBL 6 November 2001 (2001-11-06), TANG Y. ET AL.: "Human protein SEQ ID NO: 1911", XP002208268, Database accession no. AAM79249 *

Also Published As

Publication number Publication date
AU2001281933A1 (en) 2002-01-14
WO2002002599A2 (en) 2002-01-10

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