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WO2001039819A3 - Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese - Google Patents

Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese Download PDF

Info

Publication number
WO2001039819A3
WO2001039819A3 PCT/US2000/042473 US0042473W WO0139819A3 WO 2001039819 A3 WO2001039819 A3 WO 2001039819A3 US 0042473 W US0042473 W US 0042473W WO 0139819 A3 WO0139819 A3 WO 0139819A3
Authority
WO
WIPO (PCT)
Prior art keywords
cerebrospinal fluid
closed recirculation
csf
equipment
cassette
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/042473
Other languages
English (en)
Other versions
WO2001039819A2 (fr
Inventor
Glenn Frazer
Timothy J Pelura
Bruce Shook
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neuron Therapeutics Inc
Original Assignee
Neuron Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuron Therapeutics Inc filed Critical Neuron Therapeutics Inc
Priority to KR1020027007066A priority Critical patent/KR20020077351A/ko
Priority to EP00992584A priority patent/EP1235602A2/fr
Priority to AU45127/01A priority patent/AU4512701A/en
Priority to JP2001541549A priority patent/JP2003515394A/ja
Priority to CA002393221A priority patent/CA2393221A1/fr
Publication of WO2001039819A2 publication Critical patent/WO2001039819A2/fr
Publication of WO2001039819A3 publication Critical patent/WO2001039819A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0229—Devices operating in a closed circuit, i.e. recycling the irrigating fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0204—Physical characteristics of the irrigation fluid, e.g. conductivity or turbidity
    • A61M3/0216—Pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
    • A61M2027/004—Implant devices for drainage of body fluids from one part of the body to another with at least a part of the circuit outside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A61M2202/0476—Oxygenated solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3344—Measuring or controlling pressure at the body treatment site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
    • A61M27/006—Cerebrospinal drainage; Accessories therefor, e.g. valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0201—Cassettes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00—Medical syringes, e.g. enemata; Irrigators
    • A61M3/02—Enemata; Irrigators
    • A61M3/0233—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs
    • A61M3/0254—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs the liquid being pumped
    • A61M3/0258—Enemata; Irrigators characterised by liquid supply means, e.g. from pressurised reservoirs the liquid being pumped by means of electric pumps

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Sustainable Development (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • External Artificial Organs (AREA)

Abstract

De manière générale, cette invention concerne des procédés et des dispositifs permettant de mettre en oeuvre une recirculation en circuit fermé de liquide céphalo-rachidien (LCR), en principe d'origine synthétique, à travers les régions cérébrales et rachidiennes du corps et l'équipement de régénération et de revitalisation. Dans une réalisation préférée présentée sous forme d'une cassette, ce dispositif comprend un ensemble modulaire de matériel jetable, arrangé de préférence d'une manière permettant une utilisation rapide et aisée en cas d'urgence. Cette cassette contient de préférence tous les composants ou la plupart des composants qui composent le circuit de liquide permettant le conditionnement du LCR thérapeutique recirculé en provenance et en direction du patient.
PCT/US2000/042473 1999-12-03 2000-12-01 Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese Ceased WO2001039819A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
KR1020027007066A KR20020077351A (ko) 1999-12-03 2000-12-01 합성 뇌척수액의 폐쇄 재순환을 위한 방법 및 기구
EP00992584A EP1235602A2 (fr) 1999-12-03 2000-12-01 Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese
AU45127/01A AU4512701A (en) 1999-12-03 2000-12-01 Method and apparatus for closed recirculation of synthetic cerebrospinal fluid
JP2001541549A JP2003515394A (ja) 1999-12-03 2000-12-01 合成脳脊髄液の閉鎖系再循環法および装置
CA002393221A CA2393221A1 (fr) 1999-12-03 2000-12-01 Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45489399A 1999-12-03 1999-12-03
US09/454,893 1999-12-03

Publications (2)

Publication Number Publication Date
WO2001039819A2 WO2001039819A2 (fr) 2001-06-07
WO2001039819A3 true WO2001039819A3 (fr) 2002-03-14

Family

ID=23806494

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/042473 Ceased WO2001039819A2 (fr) 1999-12-03 2000-12-01 Procede et dispositif permettant la recirculation en circuit ferme d'un liquide cephalo-rachidien de synthese

Country Status (7)

Country Link
EP (1) EP1235602A2 (fr)
JP (1) JP2003515394A (fr)
KR (1) KR20020077351A (fr)
CN (1) CN1433328A (fr)
AU (1) AU4512701A (fr)
CA (1) CA2393221A1 (fr)
WO (1) WO2001039819A2 (fr)

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US6689756B2 (en) * 2001-03-02 2004-02-10 Integra Lifesciences Corporation Treatment of neurological disease
CA2411569A1 (fr) * 2002-11-12 2004-05-12 Ross E. Mantle Dispositif medical pour la recirculation extravasculaire de fluides a l'interieur de cavites corporelles dans des conditions de temperature et de pression controlees
US7004961B2 (en) * 2003-01-09 2006-02-28 Edward Wong Medical device and method for temperature control and treatment of the brain and spinal cord
CA2616037A1 (fr) 2005-07-21 2007-02-01 The Cleveland Clinic Foundation Dispositifs medicaux oscillants intracraniens et leurs utilisations
US7699799B2 (en) 2005-08-26 2010-04-20 Ceeben Systems, Inc. Ultrasonic material removal system for cardiopulmonary bypass and other applications
US20070093697A1 (en) 2005-10-21 2007-04-26 Theranova, Llc Method and apparatus for detection of right to left shunting in the cardiopulmonary vasculature
US20180311071A1 (en) * 2005-10-21 2018-11-01 Daniel R. BURNETT Method and apparatus for peritoneal oxygenation
US10569064B2 (en) 2013-03-13 2020-02-25 Minnetronix, Inc. Devices and methods for providing focal cooling to the brain and spinal cord
US10850235B2 (en) 2006-10-09 2020-12-01 Minnetronix, Inc. Method for filtering cerebrospinal fluid (CSF) including monitoring CSF flow
US10695545B2 (en) 2006-10-09 2020-06-30 Minnetronix, Inc. Systems and methods for the conditioning of cerebrospinal fluid
EP3827841B1 (fr) * 2006-10-09 2024-04-03 Neurofluidics, Inc. Système de purification de fluide cérébrospinal
US10632237B2 (en) 2006-10-09 2020-04-28 Minnetronix, Inc. Tangential flow filter system for the filtration of materials from biologic fluids
EP2155300A1 (fr) 2007-04-05 2010-02-24 Velomedix, Inc Système de thérapie automatisé et procédé associé
US8123714B2 (en) * 2007-06-29 2012-02-28 Codman & Shurtleff, Inc. Programmable shunt with electromechanical valve actuator
CA2693774A1 (fr) 2007-07-09 2009-01-15 Velomedix, Inc. Dispositifs et procedes d'hypothermie
WO2009058353A1 (fr) 2007-11-02 2009-05-07 The Cleveland Clinic Foundation Dispositif pour augmenter le débit sanguin cérébral
WO2011114260A1 (fr) * 2010-03-19 2011-09-22 Pfizer Inc. Système de purification de liquide céphalorachidien
US9622670B2 (en) 2010-07-09 2017-04-18 Potrero Medical, Inc. Method and apparatus for pressure measurement
CN103706025A (zh) * 2013-12-23 2014-04-09 李桂亮 一种埋置式蛛网膜下腔微量缓释注射器
US11147540B2 (en) 2015-07-01 2021-10-19 Minnetronix, Inc. Introducer sheath and puncture tool for the introduction and placement of a catheter in tissue
ES2906952T3 (es) * 2015-08-05 2022-04-21 Minnetronix Inc Sistema de filtro de flujo tangencial para la filtración de materiales a partir de fluidos biológicos
AU2016333997B2 (en) 2015-10-06 2019-06-06 Pharaoh Neuro, Inc. Devices and methods for providing focal cooling to the brain and spinal cord
JP6654242B2 (ja) * 2015-12-04 2020-02-26 ミネトロニクス， インコーポレイテッド 脳脊髄液を処置するためのシステム
CN111818960A (zh) * 2017-10-05 2020-10-23 米奈特朗尼克斯有限公司 用于沿中枢神经系统进行治疗的系统、导管和方法
CN107993546B (zh) * 2018-01-16 2019-09-06 西安市红会医院 一种脑脊液循环体外模型及脑积水体外模拟方法
AU2020271894A1 (en) 2019-04-11 2021-12-02 Enclear Therapies, Inc. Methods of amelioration of cerebrospinal fluid and devices and systems therefor
CN110575573B (zh) * 2019-09-24 2020-12-22 福建医科大学附属第一医院 一种用于人工脑脊液持续净化治疗的一次性管路安装系统
US11559626B2 (en) * 2020-04-08 2023-01-24 Medtronic, Inc. Means to treat Alzheimer's disease via flushing of brain parenchyma
CN115867330A (zh) 2020-05-11 2023-03-28 米奈特朗尼克斯神经有限公司 过滤匣盒及过滤系统
IL301751A (en) * 2020-09-29 2023-05-01 Enclear Therapies Inc Subarachnoid fluid management method and system
JPWO2022181126A1 (fr) * 2021-02-26 2022-09-01
AU2022315184A1 (en) * 2021-07-19 2024-03-07 Enclear Therapies, Inc. Csf diagnostics platform
GR1010335B (el) * 2022-02-11 2022-11-09 Αναστασιος Γεωργιου Τσογκας Συσκευη αποτροπης πνευμοκεφαλου

Citations (4)

* Cited by examiner, † Cited by third party
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US4686085A (en) * 1980-04-14 1987-08-11 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
WO1988008728A1 (fr) * 1987-05-15 1988-11-17 The Dis Corporation Dispositif et procede de perfusion d'une tete d'animal
WO1997032621A1 (fr) * 1996-03-08 1997-09-12 Life Resuscitation Technologies, Inc. Procede et dispositif de ventilation liquide
US5716318A (en) * 1995-04-14 1998-02-10 The University Of North Carolina At Chapel Hill Method of treating cardiac arrest and apparatus for same

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US4981691A (en) 1980-04-14 1991-01-01 Thomas Jefferson University Oxygenated fluorocarbon nutrient solution
US4378797A (en) 1980-04-14 1983-04-05 Thomas Jefferson University Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US5772607A (en) 1995-06-06 1998-06-30 The Nemours Foundation Body fluid collection apparatus
US5823987A (en) 1996-01-11 1998-10-20 Medtronic, Inc. Compact membrane-type blood oxygenator with concentric heat exchanger
JP3803421B2 (ja) 1996-04-26 2006-08-02 富士システムズ株式会社 気体交換装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686085A (en) * 1980-04-14 1987-08-11 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
WO1988008728A1 (fr) * 1987-05-15 1988-11-17 The Dis Corporation Dispositif et procede de perfusion d'une tete d'animal
US5716318A (en) * 1995-04-14 1998-02-10 The University Of North Carolina At Chapel Hill Method of treating cardiac arrest and apparatus for same
WO1997032621A1 (fr) * 1996-03-08 1997-09-12 Life Resuscitation Technologies, Inc. Procede et dispositif de ventilation liquide

Also Published As

Publication number Publication date
KR20020077351A (ko) 2002-10-11
WO2001039819A2 (fr) 2001-06-07
JP2003515394A (ja) 2003-05-07
AU4512701A (en) 2001-06-12
CN1433328A (zh) 2003-07-30
CA2393221A1 (fr) 2001-06-07
EP1235602A2 (fr) 2002-09-04

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