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WO2001038844A3 - Dispositifs d"electrophorese capillaire comportant des guides d"ondes optiques - Google Patents

Dispositifs d"electrophorese capillaire comportant des guides d"ondes optiques Download PDF

Info

Publication number
WO2001038844A3
WO2001038844A3 PCT/US2000/042067 US0042067W WO0138844A3 WO 2001038844 A3 WO2001038844 A3 WO 2001038844A3 US 0042067 W US0042067 W US 0042067W WO 0138844 A3 WO0138844 A3 WO 0138844A3
Authority
WO
WIPO (PCT)
Prior art keywords
capillary electrophoresis
optical waveguides
devices incorporating
incorporating optical
electrophoresis devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/042067
Other languages
English (en)
Other versions
WO2001038844A2 (fr
Inventor
Barbara Foley
Jaymie Sawyer
Cynthia G Briscoe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Motorola Solutions Inc
Original Assignee
Motorola Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Motorola Inc filed Critical Motorola Inc
Priority to AU43040/01A priority Critical patent/AU4304001A/en
Publication of WO2001038844A2 publication Critical patent/WO2001038844A2/fr
Anticipated expiration legal-status Critical
Publication of WO2001038844A3 publication Critical patent/WO2001038844A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44782—Apparatus specially adapted therefor of a plurality of samples

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Integrated Circuits (AREA)

Abstract

L"invention concerne un dispositif d"électrophorèse optique composé d"une couche de substrat et d"une couche de couverture, une pluralité de canaux d"électrophorèse étant formés dans la couche de substrat. Ledit dispositif est pourvu d"un système de guides d"ondes optiques transmettant un rayonnement d"excitation d"un port source vers chaque canal d"excitation. Le système de guides d"ondes optiques est défini par des régions dans la couverture ou le substrat ayant un indice de réfraction supérieur à celui du matériau environnant.
PCT/US2000/042067 1999-11-12 2000-11-10 Dispositifs d"electrophorese capillaire comportant des guides d"ondes optiques Ceased WO2001038844A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU43040/01A AU4304001A (en) 1999-11-12 2000-11-10 Capillary electrophoresis devices incorporating optical waveguides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/438,873 US6592733B1 (en) 1999-11-12 1999-11-12 Capillary electrophoresis devices incorporating optical waveguides
US09/438,873 1999-11-12

Publications (2)

Publication Number Publication Date
WO2001038844A2 WO2001038844A2 (fr) 2001-05-31
WO2001038844A3 true WO2001038844A3 (fr) 2002-06-20

Family

ID=23742376

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/042067 Ceased WO2001038844A2 (fr) 1999-11-12 2000-11-10 Dispositifs d"electrophorese capillaire comportant des guides d"ondes optiques

Country Status (3)

Country Link
US (1) US6592733B1 (fr)
AU (1) AU4304001A (fr)
WO (1) WO2001038844A2 (fr)

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US7485454B1 (en) 2000-03-10 2009-02-03 Bioprocessors Corp. Microreactor
JP3893849B2 (ja) * 2000-05-15 2007-03-14 株式会社日立製作所 キャピラリアレイ電気泳動装置及び電気泳動方法
AU2002303311B2 (en) * 2001-04-10 2007-01-25 Bioprocessors Corporation Microfermentor device and cell based screening method
US20050238506A1 (en) * 2002-06-21 2005-10-27 The Charles Stark Draper Laboratory, Inc. Electromagnetically-actuated microfluidic flow regulators and related applications
US7309467B2 (en) * 2003-06-24 2007-12-18 Hewlett-Packard Development Company, L.P. Fluidic MEMS device
WO2005072793A1 (fr) * 2004-01-29 2005-08-11 The Charles Stark Draper Laboratory, Inc. Dispositif implantable d'apport de medicament
US7867194B2 (en) 2004-01-29 2011-01-11 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
US20080258086A1 (en) * 2004-09-03 2008-10-23 Alan Mathewson Optical Detector
KR100647317B1 (ko) * 2005-02-03 2006-11-23 삼성전자주식회사 다채널 형광 측정용 광학계 및 이를 채용한 다채널 형광시료 분석 장치
US10247699B2 (en) * 2006-11-23 2019-04-02 Asmag-Holding Gmbh System for detecting electrophoresis
US9046192B2 (en) 2007-01-31 2015-06-02 The Charles Stark Draper Laboratory, Inc. Membrane-based fluid control in microfluidic devices
US20100032582A1 (en) * 2008-08-07 2010-02-11 General Electric Company Fluorescence detection system and method
CN102667463B (zh) 2010-01-28 2016-09-07 光鼎生物科技股份有限公司 利用球形末端的入射和输出光纤和/或共平面的入射和输出光导和分离通道的生物分析
US8876795B2 (en) 2011-02-02 2014-11-04 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
WO2013039778A2 (fr) 2011-09-12 2013-03-21 The University Of North Carolina At Chapel Hill Dispositifs comprenant un nanocanal de transport de fluide entrecoupé par un nanocanal de détection de fluide et procédés correspondants
US9989515B2 (en) 2012-02-10 2018-06-05 The University Of North Carolina At Chapel Hill Devices with fluidic nanofunnels, associated methods, fabrication and analysis systems
KR20150132125A (ko) * 2013-02-28 2015-11-25 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 거대분자의 통제된 포획, 고정, 및 전달을 위한 통합된 부품을 가진 나노유체 장치 및 관련 분석 방법
AU2014249081B2 (en) 2013-03-13 2019-06-27 The University Of North Carolina At Chapel Hill Nanofluidic devices for the rapid mapping of whole genomes and related systems and methods of analysis
CN107209107A (zh) * 2015-04-30 2017-09-26 惠普发展公司有限责任合伙企业 微流体光学流体传感器

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0581413A2 (fr) * 1992-07-17 1994-02-02 Beckman Instruments, Inc. Système d'électrophorèse capillaire à canaux multiples
WO1994018552A1 (fr) * 1993-02-05 1994-08-18 Iowa State University Research Foundation, Inc. Detecteur de fluorescence multiplexe destine a l'electrophorese capillaire
WO1998010122A1 (fr) * 1996-09-03 1998-03-12 Northeastern University Reseau capillaire hybride a microstructure et ensemble de detection a canaux multiples
WO1998022799A2 (fr) * 1996-11-18 1998-05-28 Novartis Ag Dispositif de mesure et son utilisation
WO1998023945A1 (fr) * 1996-11-27 1998-06-04 Optical Analytic Inc. Dispositif de photodetection perimetrique permettant un captage accru du rayonnement
US5790727A (en) * 1997-02-05 1998-08-04 Brookhaven Science Associates Llc Laser illumination of multiple capillaries that form a waveguide
WO1999037996A1 (fr) * 1998-01-23 1999-07-29 Torsana Biosensor A/S Detection d'une substance par les modifications de l'indice de refraction

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US5292620A (en) 1988-01-15 1994-03-08 E. I. Du Pont De Nemours And Company Optical waveguide devices, elements for making the devices and methods of making the devices and elements
US5935401A (en) 1996-09-18 1999-08-10 Aclara Biosciences Surface modified electrophoretic chambers
US5194915A (en) 1990-09-20 1993-03-16 Millipore Corporation Photometric apparatus and process
DE4139211C2 (de) 1990-11-30 1994-03-24 Hitachi Ltd Elektrophoresegerät
US5302272A (en) 1992-03-05 1994-04-12 Beckman Instruments, Inc. Fiber optic flow cell for detection of electrophoresis separation with a capillary column and method of making same
US5312535A (en) 1992-07-17 1994-05-17 Beckman Instruments, Inc. Capillary electrophoresis detection
US5439578A (en) 1993-06-03 1995-08-08 The Governors Of The University Of Alberta Multiple capillary biochemical analyzer
JP3340544B2 (ja) 1993-12-24 2002-11-05 株式会社日立製作所 分別採取装置及び分別採取方法
US5500071A (en) 1994-10-19 1996-03-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
US5582705A (en) 1995-05-19 1996-12-10 Iowa State University Research Foundation, Inc. Multiplexed capillary electrophoresis system
US5545901A (en) 1995-08-23 1996-08-13 Beckman Instruments, Inc. Automated optical alignment using a galvometric scanner
DE69735189T2 (de) 1996-02-20 2006-10-26 Waters Investments Ltd., Milford Sensor für kapillarelektrophorese
US5885470A (en) 1997-04-14 1999-03-23 Caliper Technologies Corporation Controlled fluid transport in microfabricated polymeric substrates
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US5867266A (en) 1996-04-17 1999-02-02 Cornell Research Foundation, Inc. Multiple optical channels for chemical analysis
JP3559648B2 (ja) 1996-04-23 2004-09-02 株式会社日立製作所 キャピラリーアレー電気泳動装置
US5898493A (en) 1996-06-07 1999-04-27 Iowa State University Research Foundation, Inc. Capillary electrophoresis-fluorescence line narrowing system (CE-FLNS) for on-line structural characterization
US5763277A (en) 1996-06-10 1998-06-09 Transgenomic Incorporated Fiber optic axial view fluorescence detector and method of use
EP0854362A3 (fr) 1997-01-16 2000-12-20 Japan Science and Technology Corporation Appareil d'électrophorèse à capillaires multiples
US5954931A (en) 1997-01-24 1999-09-21 Motorola, Inc. Electrophoresis apparatus and method involving parallel channels
GB9810350D0 (en) * 1998-05-14 1998-07-15 Ciba Geigy Ag Organic compounds
US6438279B1 (en) * 1999-01-07 2002-08-20 Cornell Research Foundation, Inc. Unitary microcapiliary and waveguide structure and method of fabrication

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0581413A2 (fr) * 1992-07-17 1994-02-02 Beckman Instruments, Inc. Système d'électrophorèse capillaire à canaux multiples
WO1994018552A1 (fr) * 1993-02-05 1994-08-18 Iowa State University Research Foundation, Inc. Detecteur de fluorescence multiplexe destine a l'electrophorese capillaire
WO1998010122A1 (fr) * 1996-09-03 1998-03-12 Northeastern University Reseau capillaire hybride a microstructure et ensemble de detection a canaux multiples
WO1998022799A2 (fr) * 1996-11-18 1998-05-28 Novartis Ag Dispositif de mesure et son utilisation
WO1998023945A1 (fr) * 1996-11-27 1998-06-04 Optical Analytic Inc. Dispositif de photodetection perimetrique permettant un captage accru du rayonnement
US5790727A (en) * 1997-02-05 1998-08-04 Brookhaven Science Associates Llc Laser illumination of multiple capillaries that form a waveguide
WO1999037996A1 (fr) * 1998-01-23 1999-07-29 Torsana Biosensor A/S Detection d'une substance par les modifications de l'indice de refraction

Also Published As

Publication number Publication date
WO2001038844A2 (fr) 2001-05-31
AU4304001A (en) 2001-06-04
US6592733B1 (en) 2003-07-15

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