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WO2001098314A3 - Novel motor proteins and methods for their use - Google Patents

Novel motor proteins and methods for their use Download PDF

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Publication number
WO2001098314A3
WO2001098314A3 PCT/US2001/019811 US0119811W WO0198314A3 WO 2001098314 A3 WO2001098314 A3 WO 2001098314A3 US 0119811 W US0119811 W US 0119811W WO 0198314 A3 WO0198314 A3 WO 0198314A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
hskif17
novel motor
motor proteins
modulators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/019811
Other languages
French (fr)
Other versions
WO2001098314A2 (en
Inventor
Christophe Beraud
Richard Freedman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytokinetics Inc
Original Assignee
Cytokinetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytokinetics Inc filed Critical Cytokinetics Inc
Priority to AU2001268637A priority Critical patent/AU2001268637A1/en
Priority to US10/311,642 priority patent/US20040086878A1/en
Publication of WO2001098314A2 publication Critical patent/WO2001098314A2/en
Publication of WO2001098314A3 publication Critical patent/WO2001098314A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention provides isolated nucleic acid and amino acid sequences of HsKif17, antibodies to HsKif17, methods of screening for HsKif17 modulators using biologically active HsKif17, and kits for screening for HsKif17 modulators.
PCT/US2001/019811 2000-06-20 2001-06-20 Novel motor proteins and methods for their use Ceased WO2001098314A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001268637A AU2001268637A1 (en) 2000-06-20 2001-06-20 Novel motor proteins and methods for their use
US10/311,642 US20040086878A1 (en) 2001-06-20 2001-06-20 Novel motor proteins and methods for their use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59760200A 2000-06-20 2000-06-20
US09/597,602 2000-06-20

Publications (2)

Publication Number Publication Date
WO2001098314A2 WO2001098314A2 (en) 2001-12-27
WO2001098314A3 true WO2001098314A3 (en) 2002-05-16

Family

ID=24392177

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/019811 Ceased WO2001098314A2 (en) 2000-06-20 2001-06-20 Novel motor proteins and methods for their use

Country Status (2)

Country Link
AU (1) AU2001268637A1 (en)
WO (1) WO2001098314A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9717754B2 (en) * 2003-02-27 2017-08-01 Enzo Therapeutics, Inc. Glucocerebroside treatment of disease

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 15 November 1997 (1997-11-15), SETOU ET AL.: "Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport", XP002906421, Database accession no. AB008867 *
DATABASE GENBANK [online] 31 January 2000 (2000-01-31), OHARA ET AL.: "Prediction of the coding sequence of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro", XP002906420, Database accession no. AB037826 *
HIROKAWA N.: "Kinesin and dynein superfamily proteins and the mechanism of organelle transport", SCIENCE, vol. 279, 23 January 1998 (1998-01-23), pages 519 - 526, XP002906419 *
SAKOWICZ R. ET AL.: "A marine natural product inhibitor of kinesin motors", SCIENCE, vol. 280, 10 April 1998 (1998-04-10), pages 292 - 295, XP002906416 *
SETOU M. ET AL.: "Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport", SCIENCE, vol. 288, 9 June 2000 (2000-06-09), pages 1796 - 1802, XP002906422 *
TUCKER C. ET AL.: "Probing the kinesin-microtubule interaction", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 14, 4 April 1997 (1997-04-04), pages 9481 - 9488, XP002906417 *
YAMAZAKI H. ET AL.: "KIF3A/B: A heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport", JOURNAL OF CELL BIOLOGY, vol. 130, no. 6, September 1995 (1995-09-01), pages 1387 - 1399, XP002906418 *

Also Published As

Publication number Publication date
AU2001268637A1 (en) 2002-01-02
WO2001098314A2 (en) 2001-12-27

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