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WO2001088135A3 - G-protein coupled receptor proteins and nucleic acids encoding same - Google Patents

G-protein coupled receptor proteins and nucleic acids encoding same Download PDF

Info

Publication number
WO2001088135A3
WO2001088135A3 PCT/US2001/015526 US0115526W WO0188135A3 WO 2001088135 A3 WO2001088135 A3 WO 2001088135A3 US 0115526 W US0115526 W US 0115526W WO 0188135 A3 WO0188135 A3 WO 0188135A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
acids encoding
coupled receptor
protein coupled
receptor proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/015526
Other languages
French (fr)
Other versions
WO2001088135A2 (en
Inventor
Muralidhara Padigaru
William M Grosse
Edward D Szerkeres
Stacie J Casman
John P Alsobrook Iii
Catherine E Burgess
Sarah Taylor
Corine A M Vernet
Jason C Baumgartner
Velizar T Tchernev
Kimberly A Spytek
Li Li
Suresh Shenoy
Ramesha Kekuda
Esha A Gangolli
David J Stone
Glennda Smithson
John R Macdougall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CuraGen Corp
Original Assignee
CuraGen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CuraGen Corp filed Critical CuraGen Corp
Priority to AU2001268060A priority Critical patent/AU2001268060A1/en
Publication of WO2001088135A2 publication Critical patent/WO2001088135A2/en
Publication of WO2001088135A3 publication Critical patent/WO2001088135A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
PCT/US2001/015526 2000-05-15 2001-05-15 G-protein coupled receptor proteins and nucleic acids encoding same Ceased WO2001088135A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001268060A AU2001268060A1 (en) 2000-05-15 2001-05-15 G-protein coupled receptor proteins and nucleic acids encoding same

Applications Claiming Priority (28)

Application Number Priority Date Filing Date Title
US20410600P 2000-05-15 2000-05-15
US60/204,106 2000-05-15
US22052600P 2000-07-24 2000-07-24
US60/220,526 2000-07-24
US22128800P 2000-07-27 2000-07-27
US60/221,288 2000-07-27
US25808300P 2000-12-22 2000-12-22
US60/258,083 2000-12-22
US25851500P 2000-12-28 2000-12-28
US25850800P 2000-12-28 2000-12-28
US60/258,515 2000-12-28
US60/258,508 2000-12-28
US25964201P 2001-01-04 2001-01-04
US60/259,642 2001-01-04
US26258901P 2001-01-18 2001-01-18
US60/262,589 2001-01-18
US26321401P 2001-01-22 2001-01-22
US60/263,214 2001-01-22
US26341001P 2001-01-23 2001-01-23
US60/263,410 2001-01-23
US26613001P 2001-02-02 2001-02-02
US60/266,130 2001-02-02
US27416901P 2001-03-08 2001-03-08
US60/274,169 2001-03-08
US27485901P 2001-03-09 2001-03-09
US60/274,859 2001-03-09
US27560301P 2001-03-13 2001-03-13
US60/275,603 2001-03-13

Publications (2)

Publication Number Publication Date
WO2001088135A2 WO2001088135A2 (en) 2001-11-22
WO2001088135A3 true WO2001088135A3 (en) 2002-08-29

Family

ID=27585091

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/015526 Ceased WO2001088135A2 (en) 2000-05-15 2001-05-15 G-protein coupled receptor proteins and nucleic acids encoding same

Country Status (1)

Country Link
WO (1) WO2001088135A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040106149A1 (en) * 2000-09-20 2004-06-03 Franz-Werner Kluxen Novel gpcr hfrbn63
US20020072488A1 (en) * 2000-12-12 2002-06-13 Merkulov Gennady V. Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'
WO2001064905A2 (en) * 2000-02-29 2001-09-07 Millennium Pharmaceuticals, Inc. 2504, 15977, and 14760, novel protein kinase family members and uses therefor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'
WO2001064905A2 (en) * 2000-02-29 2001-09-07 Millennium Pharmaceuticals, Inc. 2504, 15977, and 14760, novel protein kinase family members and uses therefor

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_HUM EBI Hinxton, UK; 13 March 2000 (2000-03-13), BROWN A ET AL.: "Human DNA sequence of clone RP11-243J16 on chromosome 20", XP002192641 *
HERRING B P ET AL: "DOMAIN CHARACTERIZATION OF RABBIT SKELETAL MUSCLE MYOSIN LIGHT CHAIN KINASE", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 265, no. 3, 25 January 1990 (1990-01-25), pages 1724 - 1730, XP000979556, ISSN: 0021-9258 *
STADEL J M ET AL: "Orphan G protein-coupled receptors: a neglected opportunity for pioneer drug discovery", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER TRENDS JOURNAL, CAMBRIDGE, GB, vol. 18, no. 11, 1 November 1997 (1997-11-01), pages 430 - 437, XP004099345, ISSN: 0165-6147 *

Also Published As

Publication number Publication date
WO2001088135A2 (en) 2001-11-22

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