WO2001066689A3 - Nouveaux acides nucleiques et polypeptides - Google Patents
Nouveaux acides nucleiques et polypeptides Download PDFInfo
- Publication number
- WO2001066689A3 WO2001066689A3 PCT/US2001/004942 US0104942W WO0166689A3 WO 2001066689 A3 WO2001066689 A3 WO 2001066689A3 US 0104942 W US0104942 W US 0104942W WO 0166689 A3 WO0166689 A3 WO 0166689A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acids
- polypeptides
- novel nucleic
- novel
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2001245280A AU2001245280A1 (en) | 2000-03-07 | 2001-03-05 | Novel nucleic acids and polypeptides |
| US10/221,278 US20040034208A1 (en) | 2001-03-05 | 2001-03-05 | Novel nucleic acids and polypeptides |
| CA002402293A CA2402293A1 (fr) | 2000-03-07 | 2001-03-05 | Nouveaux acides nucleiques et polypeptides |
| EP01918174A EP1261743A2 (fr) | 2000-03-07 | 2001-03-05 | Nouveaux acides nucleiques et polypeptides |
| US10/291,172 US20030228584A1 (en) | 2000-03-07 | 2002-11-08 | Novel nucleic acids and polypeptides |
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51970500A | 2000-03-07 | 2000-03-07 | |
| US09/519,705 | 2000-03-07 | ||
| US57445400A | 2000-05-19 | 2000-05-19 | |
| US09/574,454 | 2000-05-19 | ||
| US59619300A | 2000-06-17 | 2000-06-17 | |
| US09/596,193 | 2000-06-17 | ||
| US61684700A | 2000-07-14 | 2000-07-14 | |
| US09/616,847 | 2000-07-14 | ||
| US66536300A | 2000-09-19 | 2000-09-19 | |
| US09/665,363 | 2000-09-19 | ||
| US69326700A | 2000-10-20 | 2000-10-20 | |
| US09/693,267 | 2000-10-20 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US10/291,172 Continuation-In-Part US20030228584A1 (en) | 2000-03-07 | 2002-11-08 | Novel nucleic acids and polypeptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001066689A2 WO2001066689A2 (fr) | 2001-09-13 |
| WO2001066689A3 true WO2001066689A3 (fr) | 2002-05-30 |
Family
ID=27560092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2001/004942 Ceased WO2001066689A2 (fr) | 2000-03-07 | 2001-03-05 | Nouveaux acides nucleiques et polypeptides |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1261743A2 (fr) |
| AU (1) | AU2001245280A1 (fr) |
| CA (1) | CA2402293A1 (fr) |
| WO (1) | WO2001066689A2 (fr) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| US7033790B2 (en) | 2001-04-03 | 2006-04-25 | Curagen Corporation | Proteins and nucleic acids encoding same |
| US7425612B2 (en) | 2002-06-06 | 2008-09-16 | Oncotherapy Science, Inc. | Genes and polypeptides relating to human colon cancers |
| US9562049B2 (en) | 2012-12-21 | 2017-02-07 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
| US9567340B2 (en) | 2012-12-21 | 2017-02-14 | Medimmune Limited | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
| WO2024138128A2 (fr) | 2022-12-23 | 2024-06-27 | Genentech, Inc. | Conjugués d'agent de dégradation de céréblon et leurs utilisations |
Families Citing this family (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6953682B2 (en) | 2000-02-10 | 2005-10-11 | Millennium Pharmaceuticals, Inc. | Nucleic acid sequences encoding adenylate kinase, phospholipid scramblase-like, DNA fragmentation factor-like, phosphatidylserine synthase-like, and atpase-like molecules and uses therefor |
| AU2002228003A1 (en) * | 2000-12-14 | 2002-06-24 | Bayer Aktiengesellschaft | Regulation of human uridine kinase |
| US20040072997A1 (en) * | 2000-12-20 | 2004-04-15 | Alsobrook John P. | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| AU2002250143A1 (en) * | 2001-03-16 | 2002-10-03 | Eli Lilly And Company | Lp mammalian proteins; related reagents |
| EP2153843B1 (fr) | 2001-09-18 | 2012-08-15 | Genentech, Inc. | Compositions et procédés pour le traitement et le diagnostic d'une tumeur |
| AU2003226444A1 (en) * | 2002-04-01 | 2003-10-13 | Asahi Kasei Pharma Corporation | Vascularization controlling gene |
| WO2005117986A2 (fr) | 2004-06-01 | 2005-12-15 | Genentech, Inc. | Conjugues de medicaments anticorps et procedes correspondants |
| US20060110731A1 (en) * | 2002-05-15 | 2006-05-25 | Reinhard Ebner | Cancer-linked gene as target for chemotherapy |
| GB0215295D0 (en) * | 2002-07-02 | 2002-08-14 | Inpharmatica Ltd | Proteins |
| EP1611239A1 (fr) * | 2003-03-26 | 2006-01-04 | Novartis AG | Proteines activateurs d'elements de reponse amp cyclique et utilisations correspondantes |
| US7361747B2 (en) * | 2003-05-22 | 2008-04-22 | The University Of Hong Kong | Isolation and characterization of the precursor virus of human SARS virus: SARS-associated corona virus-like virus |
| GB0320878D0 (en) * | 2003-09-05 | 2003-10-08 | Celltech R&D Ltd | A protein involved in carcinoma |
| EP2267154A1 (fr) | 2003-10-23 | 2010-12-29 | Illumigen Biosciences, Inc. | Oligoadenylate synthétase |
| CN103394083B (zh) | 2003-11-06 | 2017-07-18 | 西雅图基因公司 | 能够与配体偶联的单甲基缬氨酸化合物 |
| PL1791565T3 (pl) | 2004-09-23 | 2016-10-31 | Modyfikowane cysteiną przeciwciała i koniugaty | |
| US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
| WO2006097335A1 (fr) * | 2005-03-18 | 2006-09-21 | Universität Zürich | Nouvel element de la voie de signalisation wg/wnt |
| UA95446C2 (ru) | 2005-05-04 | 2011-08-10 | Іллюміджен Байосайєнсіз, Інк. | Мутаци в генах oas1 |
| ES2543341T3 (es) | 2005-09-13 | 2015-08-18 | National Research Council Of Canada | Métodos y composiciones para modular la actividad de células tumorales |
| WO2009093246A2 (fr) * | 2008-01-22 | 2009-07-30 | Compugen Ltd. | Nouveau peptide dérivé de clusterine |
| WO2011031870A1 (fr) | 2009-09-09 | 2011-03-17 | Centrose, Llc | Conjugués médicamenteux ciblés à visée extracellulaire |
| AU2010324506B2 (en) | 2009-11-24 | 2015-02-26 | Alethia Biotherapeutics Ulc | Anti-clusterin antibodies and antigen binding fragments and their use to reduce tumor volume |
| MX2012011901A (es) | 2010-04-15 | 2012-11-29 | Spirogen Sarl | Pirrolobenzodiacepinas y conjugados de las mismas. |
| CN107335062B (zh) | 2010-06-08 | 2021-09-24 | 基因泰克公司 | 半胱氨酸改造的抗体和偶联物 |
| CN103429254A (zh) * | 2010-10-11 | 2013-12-04 | 南加利福尼亚大学 | 分泌的热休克蛋白-90α(Hsp90α)片段作为用于对抗一系列人类实体肿瘤的单克隆抗体药物的疫苗或表位或小分子药物的靶点 |
| WO2012074757A1 (fr) | 2010-11-17 | 2012-06-07 | Genentech, Inc. | Conjugués d'anticorps alaninyl-maytansinol |
| CA2833212C (fr) | 2011-05-12 | 2020-06-09 | Genentech, Inc. | Reaction multiple de surveillance du procede lc-ms/ms pour detecter les anticorps therapeutiques dans les echantillons d'animaux par des peptides de signature du cadre |
| CA2850371C (fr) | 2011-10-14 | 2020-06-30 | Spirogen Sarl | Pyrrolobenzodiazepines et conjugues associes |
| US9822170B2 (en) | 2012-02-22 | 2017-11-21 | Alethia Biotherapeutics Inc. | Co-use of a clusterin inhibitor with an EGFR inhibitor to treat cancer |
| WO2013130093A1 (fr) | 2012-03-02 | 2013-09-06 | Genentech, Inc. | Biomarqueurs pour un traitement à base de composés chimiothérapeutiques anti-tubuline |
| KR101645905B1 (ko) | 2012-10-12 | 2016-08-04 | 스피로즌 살 | 피롤로벤조디아제핀 및 그의 컨주게이트 |
| HUE039329T2 (hu) | 2012-10-12 | 2018-12-28 | Adc Therapeutics Sa | Pirrolobenzodiazepin-antitest konjugátumok |
| SI2906253T1 (sl) | 2012-10-12 | 2018-11-30 | Adc Therapeutics Sa | Konjugati pirolobenzodiazepin-protitelo proti PSMA |
| WO2014057114A1 (fr) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Conjugués pyrrolobenzodiazepine-anticorps anti-psma |
| SMT201900017T1 (it) | 2012-10-12 | 2019-02-28 | Medimmune Ltd | Coniugati pirrolobenzodiazepina-anticorpo |
| ES2660029T3 (es) | 2012-10-12 | 2018-03-20 | Medimmune Limited | Conjugados de anticuerpo-pirrolobenzodiazepinas |
| BR112015008238A2 (pt) | 2012-10-12 | 2017-11-28 | Adc Therapeutics Sarl | conjugados de pirrolbenzodiazepina-anticorpo anti-cd22 |
| MX363787B (es) | 2013-03-13 | 2019-04-03 | Medimmune Ltd | Pirrolobenzodiazepinas y conjugados de los mismos. |
| WO2014140174A1 (fr) | 2013-03-13 | 2014-09-18 | Spirogen Sàrl | Pyrrolobenzodiazépines et leurs conjugués |
| CA2904044C (fr) | 2013-03-13 | 2020-03-31 | Medimmune Limited | Pyrrolobenzodiazepines et leurs conjugues |
| BR112016002829A2 (pt) | 2013-08-12 | 2017-09-19 | Genentech Inc | Composto e processo para preparar o composto de conjugado anticorpo-¿droga, composição farmacêutica, método de tratamento do câncer, kit para o tratamento do câncer, intermediário ligante¿-droga, porção e composto de porção droga de dímero cbi |
| GB201317982D0 (en) | 2013-10-11 | 2013-11-27 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
| WO2015052535A1 (fr) | 2013-10-11 | 2015-04-16 | Spirogen Sàrl | Conjugués anticorps-pyrrolobenzodiazépine |
| EP3054983B1 (fr) | 2013-10-11 | 2019-03-20 | Medimmune Limited | Conjugués anticorps-pyrrolobenzodiazépines |
| EP3054985B1 (fr) | 2013-10-11 | 2018-12-26 | Medimmune Limited | Conjugués anticorps-pyrrolobenzodiazépine |
| BR112016013258A2 (pt) | 2013-12-16 | 2018-01-16 | Genentech Inc | composto conjugado anticorpo-droga, composição farmacêutica, método para tratar câncer e kit |
| CR20160271A (es) | 2013-12-16 | 2016-12-02 | Genentech Inc | Compuestos peptidométicos y sus conjugados de anticuerpo-fármaco |
| JP6671292B2 (ja) | 2013-12-16 | 2020-03-25 | ジェネンテック, インコーポレイテッド | ペプチド模倣化合物及びその抗体−薬物コンジュゲート |
| EP3193940A1 (fr) | 2014-09-10 | 2017-07-26 | Medimmune Limited | Pyrrolobenzodiazépines et leurs conjugués |
| GB201416112D0 (en) | 2014-09-12 | 2014-10-29 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| SG11201701128YA (en) | 2014-09-12 | 2017-03-30 | Genentech Inc | Cysteine engineered antibodies and conjugates |
| CN106714844B (zh) | 2014-09-12 | 2022-08-05 | 基因泰克公司 | 蒽环类二硫化物中间体、抗体-药物缀合物和方法 |
| MA40575A (fr) | 2014-09-17 | 2016-03-24 | Genentech Inc | Pyrrolobenzodiazépines et conjugués à base de disulfure d'anticorps associés |
| MX379396B (es) | 2014-11-25 | 2025-03-11 | Adc Therapeutics Sa | Conjugados de pirrolobenzodiazepina y anticuerpo. |
| MX2017007169A (es) | 2014-12-03 | 2018-05-02 | Genentech Inc | Compuestos de amina cuaternaria y conjugados de anticuerpofármaco de los mismos. |
| GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| GB201506402D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
| MA43345A (fr) | 2015-10-02 | 2018-08-08 | Hoffmann La Roche | Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation |
| MA43354A (fr) | 2015-10-16 | 2018-08-22 | Genentech Inc | Conjugués médicamenteux à pont disulfure encombré |
| MA45326A (fr) | 2015-10-20 | 2018-08-29 | Genentech Inc | Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation |
| GB201601431D0 (en) | 2016-01-26 | 2016-03-09 | Medimmune Ltd | Pyrrolobenzodiazepines |
| GB201602359D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| GB201602356D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| US20170315132A1 (en) | 2016-03-25 | 2017-11-02 | Genentech, Inc. | Multiplexed total antibody and antibody-conjugated drug quantification assay |
| GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| GB201608197D0 (en) * | 2016-05-10 | 2016-06-22 | Ducentis Biotherapeutics Ltd | Novel proteins |
| PL3458101T3 (pl) | 2016-05-20 | 2021-05-31 | F. Hoffmann-La Roche Ag | Koniugaty PROTAC-przeciwciało i sposoby ich stosowania |
| US20170370906A1 (en) | 2016-05-27 | 2017-12-28 | Genentech, Inc. | Bioanalytical analysis of site-specific antibody drug conjugates |
| WO2017214024A1 (fr) | 2016-06-06 | 2017-12-14 | Genentech, Inc. | Médicaments conjugués d'anticorps silvestrol et procédés d'utilisation |
| EP3496763A1 (fr) | 2016-08-11 | 2019-06-19 | Genentech, Inc. | Promédicaments de pyrrolobenzodiazépine et conjugués d'anticorps de ceux-ci |
| JP7050770B2 (ja) | 2016-10-05 | 2022-04-08 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | 抗体薬物コンジュゲートの調製方法 |
| GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| US11160872B2 (en) | 2017-02-08 | 2021-11-02 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates |
| GB201702031D0 (en) | 2017-02-08 | 2017-03-22 | Medlmmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
| US11260101B2 (en) * | 2017-02-28 | 2022-03-01 | Jinan University | Repair peptide for use in promoting post-traumatic tissue repair and regeneration, and application thereof |
| WO2018192944A1 (fr) | 2017-04-18 | 2018-10-25 | Medimmune Limited | Conjugués de pyrrolobenzodiazépine |
| CA3057748A1 (fr) | 2017-04-20 | 2018-10-25 | Adc Therapeutics Sa | Polytherapie avec un conjugue anticorps anti-axl-medicament |
| KR102442736B1 (ko) | 2017-06-14 | 2022-09-16 | 에이디씨 테라퓨틱스 에스에이 | 항-cd19 adc의 투여를 위한 투약량 체제 |
| FR3069156B1 (fr) * | 2017-07-21 | 2019-08-09 | Universite de Bordeaux | Clusterine pour son utilisation dans le traitement des micro-angiopathies thrombotiques |
| SG11202000358YA (en) | 2017-08-18 | 2020-02-27 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| BR112020004307A2 (pt) | 2017-09-20 | 2020-11-10 | Ph Pharma Co., Ltd. | análogos de tailanestatina |
| GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
| GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| GB201814281D0 (en) | 2018-09-03 | 2018-10-17 | Femtogenix Ltd | Cytotoxic agents |
| AU2019365238A1 (en) | 2018-10-24 | 2021-05-13 | F. Hoffmann-La Roche Ag | Conjugated chemical inducers of degradation and methods of use |
| EP3894427A1 (fr) | 2018-12-10 | 2021-10-20 | Genentech, Inc. | Peptides de photoréticulation pour conjugaison spécifique de site à des protéines contenant fc |
| GB201901197D0 (en) | 2019-01-29 | 2019-03-20 | Femtogenix Ltd | G-A Crosslinking cytotoxic agents |
| JP7520870B2 (ja) | 2019-03-15 | 2024-07-23 | メドイミューン・リミテッド | がんの治療における使用のための、アゼチドベンゾジアゼピン二量体及びこれを含む複合体 |
| GB2597532A (en) | 2020-07-28 | 2022-02-02 | Femtogenix Ltd | Cytotoxic compounds |
| CA3236930A1 (fr) | 2021-11-03 | 2022-04-21 | Hangzhou Dac Biotech Co., Ltd. | Conjugaison specifique d'un anticorps |
| WO2024220546A2 (fr) | 2023-04-17 | 2024-10-24 | Peak Bio, Inc. | Anticorps et conjugués anticorps-médicament et procédés d'utilisation, processus synthétiques et intermédiaires |
-
2001
- 2001-03-05 AU AU2001245280A patent/AU2001245280A1/en not_active Abandoned
- 2001-03-05 EP EP01918174A patent/EP1261743A2/fr not_active Withdrawn
- 2001-03-05 WO PCT/US2001/004942 patent/WO2001066689A2/fr not_active Ceased
- 2001-03-05 CA CA002402293A patent/CA2402293A1/fr not_active Abandoned
Non-Patent Citations (2)
| Title |
|---|
| DATABASE GENBANK [online] 6 February 1997 (1997-02-06), WANG ET AL.: "Direct submission", XP002908399, Database accession no. U51114 * |
| WATSON ET AL.: "The science used in recombinant DNA industry. Recombinant DNA; A short course", 1983, W.H. FREEMAN AND COMPANY, NEW YORK, XP002945246 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7033790B2 (en) | 2001-04-03 | 2006-04-25 | Curagen Corporation | Proteins and nucleic acids encoding same |
| US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| US7425612B2 (en) | 2002-06-06 | 2008-09-16 | Oncotherapy Science, Inc. | Genes and polypeptides relating to human colon cancers |
| US7705141B2 (en) | 2002-06-06 | 2010-04-27 | Oncotherapy Science, Inc. | Genes and polypeptides relating to human colon cancers |
| US7847065B2 (en) | 2002-06-06 | 2010-12-07 | Oncotherapy Science, Inc. | CXADRL1 polypeptides relating to human cancers |
| US9562049B2 (en) | 2012-12-21 | 2017-02-07 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
| US9567340B2 (en) | 2012-12-21 | 2017-02-14 | Medimmune Limited | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
| WO2024138128A2 (fr) | 2022-12-23 | 2024-06-27 | Genentech, Inc. | Conjugués d'agent de dégradation de céréblon et leurs utilisations |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001245280A1 (en) | 2001-09-17 |
| WO2001066689A2 (fr) | 2001-09-13 |
| CA2402293A1 (fr) | 2001-09-13 |
| EP1261743A2 (fr) | 2002-12-04 |
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