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WO2001053529A3 - Determination rapide de la structure genique au moyen d'une sequence d'adnc - Google Patents

Determination rapide de la structure genique au moyen d'une sequence d'adnc Download PDF

Info

Publication number
WO2001053529A3
WO2001053529A3 PCT/US2001/001461 US0101461W WO0153529A3 WO 2001053529 A3 WO2001053529 A3 WO 2001053529A3 US 0101461 W US0101461 W US 0101461W WO 0153529 A3 WO0153529 A3 WO 0153529A3
Authority
WO
WIPO (PCT)
Prior art keywords
sequence
regions
exon
gene structure
determined
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/001461
Other languages
English (en)
Other versions
WO2001053529A9 (fr
WO2001053529A2 (fr
Inventor
Hans-Ulrich Thomann
Michael S Fitzgerald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oscient Pharmaceuticals Corp
Original Assignee
Genome Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genome Therapeutics Corp filed Critical Genome Therapeutics Corp
Priority to EP01942674A priority Critical patent/EP1294943A2/fr
Priority to AU29532/01A priority patent/AU2953201A/en
Priority to CA002398683A priority patent/CA2398683A1/fr
Publication of WO2001053529A2 publication Critical patent/WO2001053529A2/fr
Anticipated expiration legal-status Critical
Publication of WO2001053529A9 publication Critical patent/WO2001053529A9/fr
Publication of WO2001053529A3 publication Critical patent/WO2001053529A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne un procédé qui permet d'identifier des limites entre des régions de séquence codante (exon) et de séquence non codante (non-exon) de gènes. En plus de la limite entre lesdites régions, la limite entre la séquence sur les terminaisons 5' et 3' de la région non-exon est déterminée ainsi que la séquence située dans les régions non-exon, par exemple la séquence située au niveau des terminaisons 5' et 3' des régions non-exon de la séquence en amont et en aval des régions codantes du gène (c'est-à-dire dans les régions non traduites 5' et 3' respectivement). Par conséquent, il est possible de déterminer la structure génique au moyen du procédé selon l'invention, sans devoir pour autant séquencer le gène tout entier. La présente invention est utile, par exemple, pour analyser la variation de la séquence de lignée germinale.
PCT/US2001/001461 2000-01-20 2001-01-17 Determination rapide de la structure genique au moyen d'une sequence d'adnc Ceased WO2001053529A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01942674A EP1294943A2 (fr) 2000-01-20 2001-01-17 Determination rapide de la structure genique au moyen d'une sequence d'adnc
AU29532/01A AU2953201A (en) 2000-01-20 2001-01-17 Rapid determination of gene structure using cdna sequence
CA002398683A CA2398683A1 (fr) 2000-01-20 2001-01-17 Determination rapide de la structure genique au moyen d'une sequence d'adnc

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48812700A 2000-01-20 2000-01-20
US09/488,127 2000-01-20

Publications (3)

Publication Number Publication Date
WO2001053529A2 WO2001053529A2 (fr) 2001-07-26
WO2001053529A9 WO2001053529A9 (fr) 2002-10-24
WO2001053529A3 true WO2001053529A3 (fr) 2003-01-16

Family

ID=23938426

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/001461 Ceased WO2001053529A2 (fr) 2000-01-20 2001-01-17 Determination rapide de la structure genique au moyen d'une sequence d'adnc

Country Status (4)

Country Link
EP (1) EP1294943A2 (fr)
AU (1) AU2953201A (fr)
CA (1) CA2398683A1 (fr)
WO (1) WO2001053529A2 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0584446A2 (fr) * 1992-03-06 1994-03-02 E.R. SQUIBB & SONS, INC. Protéine microsomale de transfert des triglycérides
EP0613945A2 (fr) * 1993-02-25 1994-09-07 The General Hospital Corporation Merlin, gène suppresseur de tumeurs, et ses utilisations
WO1995006714A1 (fr) * 1993-09-01 1995-03-09 The Trustees Of Columbia University In The City Of New York Isolation et utilisations d'un gene de la maladie de wilson
WO1996036691A1 (fr) * 1995-05-16 1996-11-21 Ramot-Univ. Authority For Applied Research And Industrial Development Ltd. Gene de l'ataxia-telangiectasie et son organisation genomique
WO1999009147A1 (fr) * 1997-08-13 1999-02-25 Icos Corporation Version tronquee de l'acetyl-hydrolase du facteur d'activation plaquettaire
WO2000001816A1 (fr) * 1998-07-02 2000-01-13 Imperial Cancer Research Technology Limited GENE SUPPRESSEUR DE TUMEUR DBCCR1 SITUE DANS 9q32-33

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0584446A2 (fr) * 1992-03-06 1994-03-02 E.R. SQUIBB & SONS, INC. Protéine microsomale de transfert des triglycérides
EP0613945A2 (fr) * 1993-02-25 1994-09-07 The General Hospital Corporation Merlin, gène suppresseur de tumeurs, et ses utilisations
WO1995006714A1 (fr) * 1993-09-01 1995-03-09 The Trustees Of Columbia University In The City Of New York Isolation et utilisations d'un gene de la maladie de wilson
WO1996036691A1 (fr) * 1995-05-16 1996-11-21 Ramot-Univ. Authority For Applied Research And Industrial Development Ltd. Gene de l'ataxia-telangiectasie et son organisation genomique
WO1999009147A1 (fr) * 1997-08-13 1999-02-25 Icos Corporation Version tronquee de l'acetyl-hydrolase du facteur d'activation plaquettaire
WO2000001816A1 (fr) * 1998-07-02 2000-01-13 Imperial Cancer Research Technology Limited GENE SUPPRESSEUR DE TUMEUR DBCCR1 SITUE DANS 9q32-33

Also Published As

Publication number Publication date
WO2001053529A9 (fr) 2002-10-24
WO2001053529A2 (fr) 2001-07-26
EP1294943A2 (fr) 2003-03-26
CA2398683A1 (fr) 2001-07-26
AU2953201A (en) 2001-07-31

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