[go: up one dir, main page]

WO2001051090A3 - Matrices polymeriques amphiphiles et ioniques et derives de telles matrices - Google Patents

Matrices polymeriques amphiphiles et ioniques et derives de telles matrices Download PDF

Info

Publication number
WO2001051090A3
WO2001051090A3 PCT/FR2001/000064 FR0100064W WO0151090A3 WO 2001051090 A3 WO2001051090 A3 WO 2001051090A3 FR 0100064 W FR0100064 W FR 0100064W WO 0151090 A3 WO0151090 A3 WO 0151090A3
Authority
WO
WIPO (PCT)
Prior art keywords
amphilic
ionic polymer
derivatives
polymer matrixes
matrixes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2001/000064
Other languages
English (en)
Other versions
WO2001051090A2 (fr
Inventor
Miguel Ignacio De
Laurent Imbertie
Didier Betbeder
Francois Lescure
Roger Kravtzoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biovector Therapeutics SA
Original Assignee
Biovector Therapeutics SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0000329A external-priority patent/FR2803526A1/fr
Application filed by Biovector Therapeutics SA filed Critical Biovector Therapeutics SA
Priority to AU2001231865A priority Critical patent/AU2001231865A1/en
Publication of WO2001051090A2 publication Critical patent/WO2001051090A2/fr
Publication of WO2001051090A3 publication Critical patent/WO2001051090A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54—Polymers characterized by specific structures/properties
    • A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
    • A61K2800/5426—Polymers characterized by specific structures/properties characterized by the charge cationic

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Birds (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pyridine Compounds (AREA)

Abstract

La présente invention concerne un nouveau type de matrices polymériques amphiphiles et ioniques comportant une matrice hydrophile macromoléculaire portant une charge ionique positive ou négative et dans laquelle est incorporée une phase lipidique de signe contraire à celui de la matrice. L'invention se rapporte également à leur méthode de fabrication et leur utilisation.
PCT/FR2001/000064 2000-01-12 2001-01-10 Matrices polymeriques amphiphiles et ioniques et derives de telles matrices Ceased WO2001051090A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001231865A AU2001231865A1 (en) 2000-01-12 2001-01-10 Amphilic and ionic polymer matrixes and derivatives thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR00/00329 2000-01-12
FR0000329A FR2803526A1 (fr) 2000-01-12 2000-01-12 Matrices polymeriques amphiphiles et ioniques et derives de telles matrices
FR0015126A FR2803517A1 (fr) 2000-01-12 2000-11-23 Matrices plymeriques amphiphiles et ioniques et derives de telles matrices
FR00/15126 2000-11-23

Publications (2)

Publication Number Publication Date
WO2001051090A2 WO2001051090A2 (fr) 2001-07-19
WO2001051090A3 true WO2001051090A3 (fr) 2002-02-28

Family

ID=26212087

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2001/000064 Ceased WO2001051090A2 (fr) 2000-01-12 2001-01-10 Matrices polymeriques amphiphiles et ioniques et derives de telles matrices

Country Status (3)

Country Link
AU (1) AU2001231865A1 (fr)
FR (1) FR2803517A1 (fr)
WO (1) WO2001051090A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006009528A1 (fr) 2004-06-16 2006-01-26 Cargill, Incorporated Produits à base d’amidon de grains cireux réticulé cationique, procédé de production des produits à base d’amidon, et utilisation dans des produits en papier
FR2982262A1 (fr) 2011-11-03 2013-05-10 Univ De Droit Et De La Sante De Lille 2 Nanoparticule comportant un coeur charge en phospholipide et une proteine adsorbee sur ledit coeur-utilisation pour la delivrance d'une proteine dans une cellule

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757768A1 (fr) * 1996-12-27 1998-07-03 Biovector Therapeutics Sa Vecteur particulaire homeocharge et composition pharmaceutique ou cosmetique le contenant
WO1998056334A1 (fr) * 1997-06-13 1998-12-17 University Of Nebraska Board Of Regents Compositions diffusant des agents biologiques et leurs procedes de preparation
FR2766706A1 (fr) * 1997-07-30 1999-02-05 Biovector Therapeutics Sa Complexes particulaires stables de charge globale neutre ou negative de structure multilamellaire composes par au moins une substance biologiquement active globalement anionique et un constituant cationique, leur preparation et utilisation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757768A1 (fr) * 1996-12-27 1998-07-03 Biovector Therapeutics Sa Vecteur particulaire homeocharge et composition pharmaceutique ou cosmetique le contenant
WO1998056334A1 (fr) * 1997-06-13 1998-12-17 University Of Nebraska Board Of Regents Compositions diffusant des agents biologiques et leurs procedes de preparation
FR2766706A1 (fr) * 1997-07-30 1999-02-05 Biovector Therapeutics Sa Complexes particulaires stables de charge globale neutre ou negative de structure multilamellaire composes par au moins une substance biologiquement active globalement anionique et un constituant cationique, leur preparation et utilisation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LEE ROBERT J ET AL: "Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 14, 1996, pages 8481 - 8487, XP002016042, ISSN: 0021-9258 *
MAJOR M ET AL: "Characterisation and phase behaviour of phospholipid bilayers adsorbed on spherical polysaccharidic nanoparticles.", BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1327, no. 1, 1997, pages 32 - 40, XP000938309, ISSN: 0006-3002 *

Also Published As

Publication number Publication date
AU2001231865A1 (en) 2001-07-24
FR2803517A1 (fr) 2001-07-13
WO2001051090A2 (fr) 2001-07-19

Similar Documents

Publication Publication Date Title
AU6192299A (en) Functionalized derivatives of hyaluronic acid and formation of hydrogels in situusing same
CA2301018A1 (fr) Gel d'acide hyaluronique, son procede de production et substance therapeutique le contenant
AU2003282100A1 (en) Process for dissolving lipophilic compounds, and cosmetic composition
AU3793301A (en) High differential pressure electrochemical cell
CA2404057A1 (fr) Desinfection d'une surface dure avec une composition comprenant de l'essence de cannelle et/ou l'un de ses actifs
WO2002051385A8 (fr) Dispersions solides de principes actifs de nitrate
CA2299201A1 (fr) Methode pour reduire les exigences en polymere et en bentonite lors de la fabrication du papier
AU7872100A (en) Snapshot restore of application chains and applications
AU7295900A (en) Aqueous gelled composition comprising a block copolymer including at least a water soluble block and a hydrophobic block
WO2001012778A3 (fr) Floculation de produit cellulaire
NL194910B (nl) Verzwakte stam van Pseudomonas aeruginosa, alsmede een vaccin en een geneesmiddel tegen Pseudomonas aeruginosa-infecties, en een werkwijze ter bereiding van het vaccin.
EP1064909A3 (fr) Composition cosmétique à base d'emulsions eau-dans-l'huile à rapport de phase aqueuse élévé
AU2952100A (en) Size composition, method for the production of sized paper or sized cardboard, and sized paper or sized cardboard
FR2766368B1 (fr) Procede de preparation de nanocapsules de type vesiculaire, utilisables notamment comme vecteurs colloidaux de principes actifs pharmaceutiques ou autres
AU5579700A (en) Stabilizer for pharmacons
WO2002060914A3 (fr) Identification de nouveaux petits arn et orf de e. coli utilises comme mediateurs de la regulation cellulaire et intercellulaire
WO1998026997A3 (fr) Emballage
WO2001051090A3 (fr) Matrices polymeriques amphiphiles et ioniques et derives de telles matrices
AU2002246091A1 (en) Electrolyte membrane, membrane electrode units comprising the same, method for the production thereof and specific uses therefor
WO2000001841A3 (fr) Analogues d'acide hyaluronique et procedes correspondants
AU2885997A (en) Eye type bearing and process for its production
WO2000032629A3 (fr) Peptides antiviraux
AU1685801A (en) Method for cross-linking carbon or carbon material such as industrial carbon black and active carbon, use thereof in the production of electrochemical double layer capacitor electrodes
AU4722597A (en) Water-soluble polymer, process for the production of the same, and use thereof as polymeric coagulant
AU3068600A (en) Printing process combining conventional and braille printing with the aid of an offset-type printing machine

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP