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WO2001040504A3 - Methods and compositions for detecting nitroaromatic compounds - Google Patents

Methods and compositions for detecting nitroaromatic compounds Download PDF

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Publication number
WO2001040504A3
WO2001040504A3 PCT/US2000/040996 US0040996W WO0140504A3 WO 2001040504 A3 WO2001040504 A3 WO 2001040504A3 US 0040996 W US0040996 W US 0040996W WO 0140504 A3 WO0140504 A3 WO 0140504A3
Authority
WO
WIPO (PCT)
Prior art keywords
nitroaromatic compounds
compositions
methods
detecting
enzymes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/040996
Other languages
French (fr)
Other versions
WO2001040504A2 (en
WO2001040504A9 (en
Inventor
Glenn H Chambliss
Brian G Fox
Daniel R Noguera
David S Blehert
Kyle L Knoke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Priority to AU43008/01A priority Critical patent/AU4300801A/en
Publication of WO2001040504A2 publication Critical patent/WO2001040504A2/en
Anticipated expiration legal-status Critical
Publication of WO2001040504A3 publication Critical patent/WO2001040504A3/en
Publication of WO2001040504A9 publication Critical patent/WO2001040504A9/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Nitroaromatic compounds present in various sample materials may be easily and inexpensively detected in a colorimetric assay according to the present invention. The invention includes a method of detecting nitroaromatic compounds, comprising placing a sample containing a nitroaromatic compound in the presence of a xenobiotic reductase enzyme and observing the formation of a colored product. The invention also includes xenobiotic reductase enzymes, DNA sequences that encode such enzymes and derivatives thereof. The invention also includes compositions and kits for performing the assay.
PCT/US2000/040996 1999-09-27 2000-09-26 Methods and compositions for detecting nitroaromatic compounds Ceased WO2001040504A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU43008/01A AU4300801A (en) 1999-09-27 2000-09-26 Methods and compositions for detecting nitroaromatic compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15637099P 1999-09-27 1999-09-27
US60/156,370 1999-09-27

Publications (3)

Publication Number Publication Date
WO2001040504A2 WO2001040504A2 (en) 2001-06-07
WO2001040504A3 true WO2001040504A3 (en) 2002-06-06
WO2001040504A9 WO2001040504A9 (en) 2002-11-14

Family

ID=22559291

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/040996 Ceased WO2001040504A2 (en) 1999-09-27 2000-09-26 Methods and compositions for detecting nitroaromatic compounds

Country Status (2)

Country Link
AU (1) AU4300801A (en)
WO (1) WO2001040504A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201000635A (en) * 2008-05-20 2010-01-01 Dsm Ip Assets Bv Preparation of epsilon-caprolactam from (Z)-6,7-dihydro-1H-azepin-2(5H)-one
EP2123767A1 (en) * 2008-05-20 2009-11-25 DSM IP Assets B.V. Preparation of epsilon-caprolactam via lysine cyclisation
RU2562563C1 (en) * 2014-06-09 2015-09-10 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Indicator composition for detecting disinfectants with active ingredient based on quaternary ammonium compounds
RU2562577C1 (en) * 2014-06-09 2015-09-10 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Indicator composition for detecting disinfectants with active ingredient based on quaternary ammonium compounds
RU2562564C1 (en) * 2014-06-09 2015-09-10 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Indicator composition for detecting disinfectants with active ingredient based on quaternary ammonium compounds
RU2563121C1 (en) * 2014-06-09 2015-09-20 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Method for rapid detection of disinfectants with active ingredient based on quaternary ammonium compounds
RU2562578C1 (en) * 2014-06-09 2015-09-10 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Indicator composition for detecting disinfectants with active ingredient based on quaternary ammonium compounds
RU2566285C1 (en) * 2014-06-09 2015-10-20 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Method of express detection of disinfectants with active substance based on quaternary ammonium compounds
RU2566283C1 (en) * 2014-06-09 2015-10-20 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Method of express-detection of disinfectants with active substance based on quaternary ammonium compounds
RU2561056C1 (en) * 2014-06-09 2015-08-20 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Method for rapid detection of disinfectants with active ingredient based on quaternary ammonium compounds
RU2566286C1 (en) * 2014-06-09 2015-10-20 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Method of express-detection of disinfectants with active substance based on quaternary ammonium compounds
RU2562567C1 (en) * 2014-06-09 2015-09-10 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Indicator composition for detecting disinfectants with active ingredient based on quaternary ammonium compounds
RU2566284C1 (en) * 2014-06-09 2015-10-20 Федеральное государственное бюджетное учреждение "Всероссийский научно-исследовательский институт по проблемам гражданской обороны и чрезвычайных ситуаций МЧС России" (федеральный центр науки и высоких технологий) Method of express-detection of disinfectants with active substance based on quaternary ammonium compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032636A1 (en) * 1997-12-19 1999-07-01 The Secretary Of State For Defence Biodegradation of explosives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032636A1 (en) * 1997-12-19 1999-07-01 The Secretary Of State For Defence Biodegradation of explosives

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BLEHERT DAVID S ET AL: "Cloning and sequence analysis of two Pseudomonas flavoprotein xenobiotic reductases.", JOURNAL OF BACTERIOLOGY, vol. 181, no. 20, October 1999 (1999-10-01), pages 6254 - 6263, XP002182933, ISSN: 0021-9193 *
FRENCH ET AL: "Aerobic degradation of 2,4,6-trinitrotoluene by Enterobacter cloacae PB2 and by pentaerythritol tetranitrate reductase", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, WASHINGTON,DC, US, vol. 64, no. 8, August 1998 (1998-08-01), pages 2864 - 2868, XP002098648, ISSN: 0099-2240 *
VORBECK CLAUDIA ET AL: "Initial reductive reactions in aerobic microbial metabolism of 2,4,6-trinitrotoluene.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 64, no. 1, January 1998 (1998-01-01), pages 246 - 252, XP002182932, ISSN: 0099-2240 *

Also Published As

Publication number Publication date
WO2001040504A2 (en) 2001-06-07
WO2001040504A9 (en) 2002-11-14
AU4300801A (en) 2001-06-12

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