WO2000021740A1 - Method of applying powder material, tablet production method, powder material application device for upper punch, powder material application device for lower punch, powder material application device, and external lubrication compressing machine - Google Patents
Method of applying powder material, tablet production method, powder material application device for upper punch, powder material application device for lower punch, powder material application device, and external lubrication compressing machine Download PDFInfo
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- WO2000021740A1 WO2000021740A1 PCT/JP1999/005590 JP9905590W WO0021740A1 WO 2000021740 A1 WO2000021740 A1 WO 2000021740A1 JP 9905590 W JP9905590 W JP 9905590W WO 0021740 A1 WO0021740 A1 WO 0021740A1
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- Prior art keywords
- powder material
- punch
- lower punch
- powder
- punches
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/0005—Details of, or accessories for, presses; Auxiliary measures in connection with pressing for briquetting presses
- B30B15/0011—Details of, or accessories for, presses; Auxiliary measures in connection with pressing for briquetting presses lubricating means
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
- B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/30—Feeding material to presses
- B30B15/302—Feeding material in particulate or plastic state to moulding presses
- B30B15/308—Feeding material in particulate or plastic state to moulding presses in a continuous manner, e.g. for roller presses, screw extrusion presses
Definitions
- Powder material coating method Tablet manufacturing method, powder material coating device for upper punch, powder material coating device for lower punch, powder material coating device, and external lubrication type Locking Machine Technical Field
- the present invention relates to a method for applying a powder material, a method for producing a tablet, an apparatus for applying a powder material, and an external lubricating tableting machine.
- the tablet is mixed with air pulsating waves and sent to the tableting device side.
- the present invention relates to a material application device and an external lubricating tableting machine using such a powder material application device. Background art
- FIG. 34 is a process chart schematically showing a method for producing tablets using a conventional external lubricating tableting machine described in Japanese Patent Application Laid-Open No. 56-14098.
- a predetermined number on a turntable 12 1 provided with a plurality of words 122 The lubricant sprayer 191 is provided at the position of, and in the sprayer 191, the rotation of the rotary table 102 sequentially turns into The lubricant powder L is placed on the upper surface S 1 24 of the lower punch 1 2.4 inserted up to the position of.
- the sprayer 19 The lower punch with lubricant powder L placed on the upper punch 123 ⁇ and the upper surface S 123 ⁇ successively accommodated in the lubricant spraying chamber 192 by the rotation of the rotary table 121. With the die 122 inserted into the specified position, the nozzle 193 provided in the spraying chamber 19.2 moves the upper surface of each of the lower punches 124 S 124
- the molding material M is compression molded to produce tablets.
- FIG. 35 is a configuration diagram schematically showing a main part of a conventional external lubricating tableting machine described in Japanese Patent Application Laid-Open No. 7-124231 and already proposed by the present inventors.
- the external lubricating tablet press 201 is fixedly provided at a predetermined position (lubricant spray point) of the rotary table 221 of the rotary tablet press so that the rotary table 221 can slide.
- a lubricant spray chamber 213 is provided.
- An air pulsation wave generator 208 is connected to the lubricant spray chamber 21.3 via a conduit T202.
- a hopper 251 containing the lubricant powder L is connected to a lubricant discharge valve 205, which is an electromagnetic valve that can be opened and closed by an arithmetic processing unit (not shown). It is connected with interposition.
- the member indicated by T203 is a material supply pipe, and the member device indicated by 259 is compressed into the hopper 251 in order to smoothly discharge the lubricant powder L from the hopper 251.
- the air sources that supply the air are shown respectively.
- a plurality of days 222 provided on the rotary table 221 are sequentially stored by rotation of the rotary table 221.
- a plurality of Each of the plurality of upper punches 223 ⁇ 'and the plurality of lower punches 2 24 ⁇ ⁇ ⁇ rotating in synchronization with the plurality of statements 222 ⁇ ⁇ ⁇ rotated by the rotation of the rotary table 221. ⁇ Are to be accommodated in turn. ,.
- an air suction means 211 such as a blower is connected to the lubricant spray chamber 213 via a pipe T204.
- the rotary tabletting machine 202 When tablets are continuously tableted, first, the rotary tabletting machine 202 is driven to rotate the rotary table 221 and a plurality of upper punches 223... And a plurality of lower punches 224. Rotate at the rotation speed of.
- the rotation of the rotary table 221 causes a plurality of upper punches corresponding to each of the plurality of 222
- Each of the plurality of lower punches 224 is fed in order.
- the air pulsation wave generator 208 is driven to generate a positive pressure air pulsation wave in the conduit T202 as shown in FIG. 36 (a) or FIG. 36 (b).
- the positive pressure air pulsation wave shown in FIG. 36 (a) has a peak of its vibration at a higher pressure than the atmosphere outside the conduit T202, and a trough of its vibration at its large peak outside the conduit T202. It shows a wave of air pulsating at a constant frequency at a pressure approximately equal to the atmospheric pressure, and the pulsating air pulsation at positive pressure shown in Fig. 36 (b) shows that the peaks and valleys of the vibration are both Shows a wave of air pulsating at a constant frequency above atmospheric pressure outside conduit T202.
- the air suction means 211 is driven.
- the lubricant discharge valve responds to the positive pressure air pulsation wave. 205 opens and closes in conjunction.
- the lubricant discharge valve 205 is opened, the lubricant L that has dropped into the material supply pipe T 203 is sent into the conduit 213, and the airflow of the positive pressure air pulsating wave is And is fluidized and sprayed into the lubricant spray chamber 213 by nozzle means 294 provided at the end of the conduit T 202.
- the inner peripheral wall S 2 2 2 of the die 2 2 which is housed in the lubricant spraying chamber 2 13 and forms a pair, with the lower punches 2 2 4 inserted to a predetermined position.
- the lubricant powder L is applied almost simultaneously to the lower surface S2 23 of the upper punch 222 and the upper surface S224 of the lower punch 222.
- the lubricating powder L was applied, and the upper and lower punches 22, 23, and 22 were used as molding material filling points (see molding material filling points P 2 shown in FIGS. 2 and 3). ), Where the molding material (in the external lubrication method, usually contains the lubricant powder in the molding material) in the space formed by the day 222 and the lower punch 222. L added 'Not kneaded.) M is filled.
- the pre-compression point P 3 and the main compression point P 4 shown in the figure) are sent to, where they form a pair, and are compressed and formed by the upper and lower punches 22 and 22 and the tablets. To be.
- the tablets manufactured in this manner are sequentially sent to the tablet discharge point (see the tablet discharge point P5 shown in FIGS. 2 and 3), where It is to be taken out sequentially.
- This external lubricating tableting machine 201 mixes and disperses the fluidized lubricant powder L into the positive pressure air pulsating wave air stream in the lubricant spray chamber 2 13 to lubricate the lubricant powder L. It is housed in the spray agent spray chamber 2 1 3, said 2 2 2,, upper punch 2 2 3 'and lower punch 2 2 4 The inner peripheral wall S 2 2 2, the lower surface S 2 2 3 of the upper punch 2 2 3, and the upper surface S 2 2 4 of the lower punch 2 2 4 Even if the tablet is continuously compressed by the external lubrication method, even when the tablet is compressed, a punch 2 2 3 ⁇ ⁇ ⁇ 2 2 4 ⁇ ⁇ ⁇ It is possible to produce tablets at the production pace without causing squeaks and without causing tableting troubles (laminating, cabling, statesking, etc.) on the produced tablets. become.
- tablets have been Tablet with a score line in the center of the tablet
- dividable tablets with a score line at the center of the tablet and tablets with company code or product code stamped on them are externally lubricated tablet presses 101 and 201.
- tableting failure laminating, cabbing, sticking, etc. is likely to occur at the part where the tablet is scored or where the mark is provided.
- a surface modifier may be applied to the tablet surface in order to improve the wettability of the tablet surface, but even in such a case, the tablet surface may have a score line or marking. Thus, there is a problem that the surface modifier cannot be applied uniformly. Disclosure of the invention
- the present invention has been made in order to solve the above problems, and is an external lubricating tablet, in which a dividable tablet provided with a dividing line in the center of the tablet, a company code or a product code is imprinted. Even tablets can be used for continuous tableting without causing tableting troubles (laminating, cabbing, sticking, etc.), powder material (lubricant) application method, tablet manufacturing method, powder
- the purpose is to provide a body material coating device and an external lubricated keying machine.
- the present invention has been made in order to solve the above problems, and is an external lubricating tablet, in which a dividable tablet provided with a dividing line in the center of the tablet, a company code or a product code is imprinted.
- Powder material surface modifier
- Powder material can be uniformly applied to tablets, powder material (surface modifier) coating method, tablet manufacturing method, powder material coating device, and The purpose is to provide an external lubricating tablet press.
- the inventor of the present invention has proposed tableting failure (laminating, cabbing, and state) for external lubricating tablets, which are dividable tablets having a score line at the center of the tablet or tablets with a company code or product code.
- powder materials such as lubricants are generally difficult to adhere to the lower surface of the upper punch due to the gravity, while extra powder is attached to the upper surface of the lower punch. He came to realize that powder materials such as lubricants were easily deposited.
- the lower surface of the upper punch In order to uniformly apply a powder material such as a lubricant to the lower surface of the upper punch, the inner peripheral wall surface of the mortar, and the upper surface of the lower punch, the surfaces of the upper punch, At the time, rather than applying a powder material such as a lubricant, the lower surface of the upper punch, on which the powder material such as the lubricant is less likely to adhere than the surface of the lower punch, has a mortar and a lower part. In addition to the step of applying a powder material such as a lubricant to the surface of a punch, it has been found that it is preferable to apply a powder such as a lubricant under other conditions. .
- the powder material is sequentially applied to a plurality of dies for compression-molding the molding material, and a surface of each of a plurality of upper punches and a plurality of lower punches.
- a method of applying a powder material in which the powder material dispersed in the air current of the air pulsating wave is directly sprayed on the upper surface of the lower punch inserted to a predetermined position within the lower punch and the upper surface of the lower punch and the While applying the powder material to the inner peripheral wall, the powder material dispersed in the air current of the air pulsating wave is applied to the lower surface of the upper punch, which does not form a pair with the lower punch, under the air current that goes upward from below. I did it.
- binder material used herein means a lubricant powder or a surface modifier powder.
- lubricant various powdery ones can be used.
- a lubricant include metal stearates (Mg salt, Ca salt, etc.), starch powder, anhydrous silicate powder, and the like.
- Various surface modifiers can be used as long as they are powdery. Examples of such a surface modifier include carnapa wax, polyethylene glycol, silica and the like.
- a powder material is easily deposited and deposited.
- the powder material mixed with the air pulsating wave is directly sprayed on the upper surface of the lower punch, so that the excess powder material is deposited.
- the powder material is prevented from adhering and accumulating on the upper surface of the lower punch, and the powder material is uniformly applied to the upper surface of the lower punch.
- the powder material is less likely to adhere, and the inner peripheral wall where the lower punch has been inserted to a predetermined position has excess powder material blown off from the upper surface of the lower punch. Because the parts adhere, the same amount of powder material as the one applied to the upper surface of the lower punch is applied uniformly to the inner peripheral wall.
- the powder material not applied on the upper surface of the lower punch and the inner peripheral wall is mixed with air, dispersed, and sent to the lower surface of the upper punch constituting the next set in a fluidized state.
- the powder material On the lower surface of the upper punch, the powder material is put on the airflow from the lower side to the upper side with respect to the lower surface of the upper punch, so that the powder material adheres over time, so that the powder material is related to gravity.
- Approximately the same amount of powder material as that applied to the upper surface of the lower punch and the inner peripheral wall is said to be uniformly applied to the lower surface of the upper punch, which is difficult to adhere to.
- the method for applying a powder material according to claim 2 is a method for compressing and molding a molding material, wherein the powder material is sequentially applied to the surface of each of a plurality of upper punches and a plurality of lower punches. In the method of applying the material, the powder material is continuously supplied to the upper surface of the lower punch and the inner peripheral wall surface, and then to the upper punch which is not paired with the lower punch.
- the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface of the lower punch inserted to a predetermined position, so that the powder material is applied to the upper surface of the lower punch and the inner peripheral wall surface. It was then applied to the lower surface of the upper punch, which did not form a pair with the lower punch, under an airflow from below to above.
- the upper surface of the lower punch and the lower punch are inserted to predetermined positions.
- the application of the powder material to the inner peripheral wall surface and the application of the powder material to the lower surface of the upper punch are performed by a series of airflows, and the upper surface of the lower punch and the inner peripheral wall are Since the excess powder material is used for application to the lower surface of the upper punch, the powder material can be effectively used without waste.
- the method for applying a powder material according to claim 3 is the method for applying a powder material according to claim 1 or 2, wherein the lower surface of the upper punch, which does not form a pair with the lower punch, faces upward from below.
- the airflow is generated by driving a suction means having a suction port at a position above the lower surface of the upper punch, and the excess powder material is suctioned and removed by the suction means.
- a simple configuration in which suction means having a suction port is provided at a position above the lower surface of the upper punch can generate an airflow from below to above on the lower surface of the upper punch. it can.
- excess powder material for example, powder material that does not reach the upper surface of the upper punch and drifts like a cloud
- the powder material does not scatter and adhere to other equipment parts.
- the method for applying a powder material according to claim 4 is the same as the method for applying a powder material according to any one of claims 1 to 3, except that the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface is used. Excessive powder material for the upper surface of the lower punch and the inner peripheral wall of the sun is sprayed directly onto the upper surface of the lower punch inserted into the mortar to the specified position, dispersed in the air current of the air pulsating wave The place is a place where it does not conduct, and it was made to remove by suction.
- extra powder material for the upper surface of the lower punch and the inner peripheral wall among the powder materials applied to the upper surface of the lower punch and the inner peripheral wall is referred to as
- the place where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface of the lower punch inserted to the specified position is a place where it does not conduct electricity.
- the powder material applied to the upper surface of the lower punch and the inner peripheral wall of the lower punch, and the extra powder material for the upper peripheral surface of the lower punch and the inner peripheral wall of the H, may adhere to the surface of the rotating table. ing Powder is also included.
- the predetermined position in the method for applying a powder material according to any one of the first to fourth aspects is a position where the lower punch is located at the lowest position.
- the lower punch is applied to the upper surface of the lower punch and the inner peripheral wall of the die at the lowest position in the powder material is applied evenly to the inner peripheral wall of the die that comes into contact with the molding material, the molding material does not adhere when manufacturing tablets.
- tablets can be produced without causing tableting troubles such as stateing, laminating, and cabbing, so that tablet production efficiency is improved.
- the tablet manufacturing method according to claim 6, comprising a plurality of statements, a plurality of upper punches and a plurality of lower punches provided so as to correspond to each of the plurality of statements, A step of sequentially applying the powder material to the punch and a plurality of lower punches, and a pair of the powder material was applied. The upper punch and the powder material coated with the powder material were applied.
- a step of sequentially compressing and molding the molding material using a lower punch; a plurality of said steps of sequentially applying a powder material to a plurality of upper punches and a plurality of lower punches are prescribed in the statement;
- the powder material dispersed in the air current of the air pulsating wave is directly sprayed on the upper surface of the lower punch inserted up to the position of, so that the powder material is applied to the upper surface of the lower punch and the inner peripheral wall,
- the powder dispersed in the air pulsating air current is applied to the lower surface of the upper punch that is not paired with the lower punch. , It was to be applied.
- the inner peripheral wall surface, the lower surface of the upper punch, and the upper surface of the lower punch where the lower punch is inserted to a predetermined position by using the powder material applying method according to claim 1 are described.
- the powder is applied to each of the two, and the inner peripheral wall surface on which the powder material is uniformly applied is described.
- a lower punch having an upper surface applied at a time is sequentially used to compress the molding material to produce tablets.
- tablets can be manufactured using a punch uniformly coated with a surface modifying agent, so that the surface modifying agent was uniformly applied to the surface of the tablets. Tablets can be manufactured.
- the tablet manufacturing method comprising a plurality of statements, a plurality of upper punches and a plurality of lower punches provided corresponding to each of the plurality of statements, A step of sequentially applying the powder material to the punch and a plurality of lower punches, and a step of applying the powder, which is a pair of the upper punch to which the powder material is applied and the lower part to which the powder material is applied; A step of sequentially compressing the molding material by using a punch, and a step of sequentially applying the powder material to a plurality of dies, a plurality of upper punches and a plurality of lower punches, wherein the powder material is The lower punch is continuously supplied to the upper surface of the lower punch and the inner peripheral wall of the sun, and then to the upper punch which is not paired with the lower punch.
- the powder material is applied to the upper surface of the lower punch and the inner peripheral wall surface. While applying a powder charge dispersed in a stream of pulsating vibration air, the lower surface of the punch on does not make lower punch and assembled, under a stream of air directed from below upward, and as applied.
- this tablet manufacturing method the application of the powder material to the inner peripheral wall where the upper surface of the lower punch and the lower punch are inserted to a predetermined position and the application of the powder material to the lower surface of the upper punch are described in a series.
- the excess powder material is used for applying to the lower surface of the upper punch and the inner peripheral wall surface of the lower punch, the excess powder material is used for application to the lower surface of the upper punch. It can be used effectively.
- the tablet manufacturing method according to claim 8 is characterized in that, in the tablet manufacturing method according to claim 6 or claim 7, the airflow from the bottom to the top is formed on the lower surface of the upper punch which is not paired with the lower punch. This is generated by driving a suction means having a suction port at a position above the lower surface of the upper punch, and excess powder material is suctioned and removed by the suction means.
- an airflow from below to above can be generated on the lower surface of the upper punch with a simple configuration in which a suction means having a suction port is provided above the lower surface of the upper punch.
- extra powdery material for example, The powder material that drifts is immediately sucked and removed from the suction port, so that the powder material does not scatter and adhere to other device parts.
- the method for producing a tablet according to claim 9 is the method for producing a tablet according to any one of claims 6 to 8, wherein the powder material applied to the upper surface of the lower punch and the inner peripheral wall is Excessive powder material for the upper surface of the punch and the inner peripheral wall of the mortar, and the location where the powder material dispersed in the air pulsating wave air flow is directly sprayed on the upper surface of the lower punch inserted into the mortar to the specified position. Was removed by suction in places where conduction did not occur.
- the method for producing a tablet according to claim 10 is the method for producing a tablet according to any one of claims 6 to 9, wherein the predetermined position on the upper surface of the lower punch is the upper surface of the lower punch. Is the lowest position.
- a powder material is applied to the upper surface of the lower punch and the inner peripheral wall surface at a position where the lower punch is at the lowest position in the lower punch.
- the powder material is applied evenly to the inner peripheral wall of the mill that comes into contact with the molding material, the molding material does not adhere to the mill.
- Claims 11 to 16 define the configuration of the applicator for the powder material for the upper punch.
- the powder material application device for an upper punch includes a plurality of upper punches and a plurality of lower punches, and at a molding material filling point, the lower punch reaches a predetermined position.
- the molding material was filled in order, and then reached the compression point.
- the molding material filled in the box is compression-molded by a pair of mortar, upper punch and lower punch, and synchronized with a plurality of rows provided on a rotary table of a continuous tableting machine that manufactures tablets.
- the powder material is applied to the lower surface of a plurality of upper punches.
- the powder material application device for the upper punch is provided below the lower surface of the upper punches.
- the powder for the lower punch which is provided at the front part of the molding material filling point and which applies the powder material to the inner peripheral wall surface and the upper surface of the lower punch where the lower punch as a set is inserted to a predetermined position. It is provided at a position different from the body material application point, and is provided so as to be curved along the rotation path of the plurality of upper punches.
- the upper punch receiving groove and the bottom of the upper punch receiving groove The lower surface of the plurality of upper punch to move the upper punch accommodation groove, and a slit part for spraying the powder material dispersed in airflow pulsating vibration air.
- a long slit is provided on the lower surface of the upper punch for spraying the powder material dispersed in the air current of the air pulsating wave. Since the powder material is sprayed on the lower surface of the upper punch over time while the punch passes, the powder material is less likely to adhere to the lower surface of the upper punch due to gravity. Since the powder material is attached to the lower surface of the upper punch, the powder material can be evenly applied.
- An apparatus for applying a powder material for an upper punch according to claim 12 is an apparatus for applying a powder material for an upper punch according to claim 11, wherein a first suction unit is provided above the slit portion. Further, the first suction means has a suction port large enough to cover the area of the slit portion, and the suction port is provided on the outer peripheral side of the rotation track of the plurality of upper punches when viewed in a plan view.
- the first suction means is driven, an airflow from the slit to the suction port is generated above the slit due to the shape of the suction port, and the air is evenly distributed in the slit. The powder material dispersed in the container is supplied.
- the upper part of the slit is large enough to cover the area of the slit, and when viewed in a plan view, a plurality of the above-mentioned rotary table is provided on the rotary table.
- a first suction means having a suction port shaped along the outer peripheral side of the rotating orbit is provided.
- the upper punch which moves in the upper punch receiving groove, is provided on the lower surface of the upper punch provided in accordance with the following statement, while the upper punch moves from the start to the end of the long slit.
- the powder material coming from above and below from all over will continue to collide with the lower surface in a substantially vertical direction.
- the powder material which hardly adheres due to gravity due to gravity, takes a long time and blows out from the entire area of the slit to the lower part of the upper punch from above to below. Since the material is attached, the powder material can be evenly applied to the lower surface of the upper punch.
- the powder material mixed with air is made to flow in the direction opposite to the rotation direction of the turntable, the powder material mixed with air is made to flow in the forward direction with the rotation direction of the turntable.
- the powder material can be made to efficiently collide with the lower surface of the upper punch as compared with the configuration described above. -In this way, the powder material applying device for the upper punch can efficiently and uniformly apply the powder material to the lower surface of the upper punch.
- the powder material applying device for the upper punch is used, the lower surface is uniformly coated with the powder material, and the upper surface is uniformly coated with the powder material.
- Tablets can be manufactured using the lower punch that has been applied and the mortar that has been applied with powder material evenly on the inner peripheral wall, so if a lubricant is used as the powder, Thus, continuous tableting can be performed without causing any stickiness in the punch and die, and without causing tableting troubles (laminating, caving, staking, etc.). This allows the production of external lubricating tablets at the production pace.
- the surface modifier when a surface modifier is used as the powder material, the surface modifier can be uniformly applied to the punches, and if the powder material application device for the upper punch is used, the surface Since a tablet can be manufactured using a punch with the modifying agent uniformly applied, it is possible to manufacture a tablet in which the surface modifier is uniformly applied to the surface of the tablet.
- the width is approximately equal to the width of the area of the score line or the mark.
- the powder material applying device for the upper punch can be sufficiently and uniformly applied to a portion of the lower surface of the upper punch where a score line or an engraving is formed.
- a lubricant it is possible to avoid laminating, caving, and statusing in the part of the tablet where the score line or marking is provided, that is, the part where the complex unevenness is formed. Tablets can be manufactured.
- the powder material applying device for the upper punch it is difficult to apply the powder material using the conventional powder material applying device.
- the powder material can be applied sufficiently and evenly to the part that forms the powder, and if a surface modifier is used as the powder material, it has conventionally been difficult to manufacture the powder material.
- the apparatus for applying a powder material for an upper punch according to claim 14 is a shape of a slit portion of the apparatus for applying a powder material for an upper punch according to any one of claims 11 to 13. Are zigzag shaped.
- the upper punch moves in the upper punch receiving groove.
- the upper punch moves in the upper punch receiving groove as compared to a slit whose slit part is simply curved along the rotation path of the multiple upper punches.
- the lower slit of the upper punch because it has passed through the longer slit The powder material is sufficiently and uniformly applied.
- the powder material applying device for the upper punch can be sufficiently and uniformly applied to a portion of the lower surface of the upper punch where a score line or a mark is formed. If a surface modifier is used as the powder material, tablets with the surface modifier applied uniformly at the part where the score line or marking is provided can be manufactured with even higher production efficiency. Will be able to
- An apparatus for applying a powder material for an upper punch according to claim 15 is provided above the slit portion of the apparatus for applying a powder material for an upper punch according to any one of claims 11 to 14. Further, a mesh means having a predetermined hole diameter was provided.
- powder materials with different particle sizes adhere to the lower surface of the upper punch, tableting becomes difficult due to this, and the surface of the manufactured tablets becomes Since it becomes impossible to apply the powder material uniformly, it is necessary to apply the powder material having a uniform particle size to the lower surface of the upper punch as uniformly as possible.
- a mesh means having a predetermined hole diameter is provided above the slit portion, and a powder having a predetermined particle size or more is catched by the mesh means. Large powder material is prevented from adhering to the lower surface of the upper punch.
- a powder material having a uniform particle size can be uniformly applied to the lower surface of the upper punch.
- the powder material applicator for the upper punch it is possible to easily produce a tablet on which the powder material is uniformly applied on the surface without making the tableting difficult. Further, since the air flow flowing from the slit portion to the suction port of the first suction means is rectified by the mesh means, the powder material is more uniformly applied to the lower surface of the upper punch.
- An apparatus for applying a powder material for an upper punch according to claim 16 is any of claims 11 to 15
- the powder coating device for the upper punch described in the crab instead of the slit, move in the upper punch receiving groove along the rotation path of the multiple upper punches on the bottom surface of the upper punch receiving groove
- a plurality of injection holes for spraying the powder material dispersed in the air current of the air pulsating wave were arranged.
- a plurality of upper punches that move in the upper punch receiving groove along the rotation path of the upper punches on the bottom surface of the upper punch receiving groove.
- a plurality of injection holes for spraying the powder material dispersed in the air current of the air pulsating wave are arranged on the lower surface of the nozzle, so that when the powder material is sprayed from each of the plurality of injection holes, However, a certain rectifying effect can be obtained.
- the powder material hardly adheres due to the gravity, and the powder material is uniformly applied to the lower surface of the upper punch.
- Claims 17 to 22 define the configuration of the powder material application device for the lower punch.
- the term "application device for powder material for lower punch" used in the present specification means that not only the upper surface of the lower punch but also the lower punch is inserted to a predetermined position. It means a device that applies powder material to the upper inner peripheral wall.
- the powder material applying apparatus for a lower punch includes a plurality of upper punches and a plurality of lower stands, and at a molding material filling point, the lower punch reaches a predetermined position.
- the molding material is sequentially filled into the inserted mortar, and then, at the compression point, the molding material filled therein is compression-molded by a pair of mortar, upper punch and lower punch,
- a plurality of plates are fixedly mounted on a rotating table provided in the circumferential direction, and rotate in synchronization with a plurality of plates provided on a rotating table.
- a powder material application device for a lower punch which applies a powder material to the upper surfaces of a plurality of lower punches provided in the same manner, which is provided at a front stage of a molding material filling point and forms a set.
- a different position from the powder material application point for the upper punch which applies the powder material to the lower surface of the upper punch
- the mortar with the lower punch inserted to the predetermined position, which is provided and rotated, is sequentially accommodated, and the upper surface of the lower punch inserted to the predetermined position is divided into air pulsating waves.
- An outlet for spraying the scattered powder material was provided on the surface facing the rotary table.
- the powder material dispersed in the air current of the air pulsating wave is sprayed from the outlet onto the upper surface of the lower punch inserted into a predetermined position inside the lower punch. Due to the amplitude of the air pulsation wave, even if extra powder material accumulates on the upper surface of the lower punch due to gravity, due to the air pulsation wave, such extra powder material becomes As a result of being blown off from the upper surface of the lower punch, the powder material can be uniformly applied to the upper surface of the lower punch where excess powder material tends to accumulate due to gravity.
- the powder material blown off from the upper surface of the lower punch adheres to the inner peripheral wall surface of the mortar, so that the powder material can be uniformly applied to the inner peripheral wall surface of the mortar.
- the powder material applying device for a lower punch according to claim 18 is configured such that the outlet of the powder material applying device for the lower punch according to claim 17 is located directly below the outlet.
- the lower punch is inserted into the inside of the lower punch at a predetermined position, and is provided at a substantially central portion of the upper surface so as to face a substantially vertical direction.
- the air pulsation wave is mixed with the upper surface of the lower punch inserted to a predetermined position from the outlet of the through hole provided to penetrate the main body.
- the sprayed powder material is directly sprayed.
- excess powder that easily adheres or accumulates on the upper surface of the lower punch is blown off from the upper surface of the lower punch by an air pulsating wave, so that the powder material is formed on the upper surface of the lower punch.
- Uniformly applied Similarly, the powder material adhering extra to the inner peripheral wall is also blown off by the air pulsating wave, so the powder material is uniformly applied to the inner peripheral wall.
- An apparatus for applying a powder material for a lower punch according to claim 19 is a device for applying a powder material for a lower punch according to claim 17 or claim 18, which has a surface facing a rotary table.
- the powder is further housed in a powder material application device for the lower punch, and is sprayed from the discharge port onto the lower punch and the die, and the powder that is excessively attached to the lower punch and the die.
- Second suction means was provided for removing the material and excess powder material on the rotating table.
- a second suction means is provided to remove the excess powder material adhering to the lower punch and the die and the excess powder material on the rotary table. I have to.
- a molding material filling portion is provided at a position downstream of the second suction means, in the step of filling the molding material into the space formed by the lower punch and the die, the lower punch and the extra The adhering powder material and excess powder material on the rotating table can be prevented from being mixed into the molding material. As a result, an external lubricating tablet that does not contain a lubricant therein can be produced more efficiently.
- the powder material applying device for lower punches according to claim 20 is the powder material applying device for lower punches according to claim 19, wherein the second suction means is provided on a rotary table. It has a slit-shaped suction port that is long enough to force each of the plurality of objects and their surroundings so as to be substantially orthogonal to the plurality of said orbits.
- the suction port of the second suction means is provided with a length capable of covering each of the plurality of parts and the periphery thereof so as to be orthogonal to the plurality of rotation paths. Because of the formation, it is possible to efficiently remove the powder material adhering to the lower punch and the surface and the excess powder material on the rotary table by driving the second suction means. it can.
- the powder material application device for lower punches according to claim 21 is the powder material application device for lower punches according to claim 20, wherein the suction port of the second suction means is at least: The plurality of dies, which are provided on the rotary table, are located farther from the diameter of each of the plurality of dies provided from the position where the discharge port is provided.
- the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface of the lower punch is excess in the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface of the die.
- the point where the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface of the lower punch inserted to a predetermined position in the inside is said to be sucked and removed in a place where it does not conduct.
- the upper surface of the lower punch and the inner wall of the lower punch are not affected by the condition that the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface of the lower punch inserted to the predetermined position in the mortar.
- Excess powder material on the upper surface of the lower punch and on the inner peripheral wall of the applied powder material can be removed by suction.
- excess powder material for the upper surface of the lower punch and the inner peripheral wall adheres to the surface of the rotary table. Powder materials are also included.
- a rotary table of the powder material applying apparatus for a lower punch according to any one of claims 17 to 21.
- a third suction means having a slit-shaped molding material suction port having a width substantially equal to or slightly larger than a diameter of each of the plurality of dies so as to be substantially orthogonal to the plurality of rotation orbits is provided.
- a third suction means having a molding material suction port is provided at a front stage of the discharge port for discharging the lubricant, and before spraying the lubricant, The inner peripheral wall surface and the upper surface of the lower punch are cleaned to prevent the molding material and lubricant used in the previous process from being mixed into the tablet in the next process.
- Claims 23 to 34 define the configuration of a powder material application device in which a powder material application device for the lower punch and an application device for the powder material for the upper punch are combined.
- the powder material application device is a powder compression device that is provided in a continuous tableting machine at a predetermined position on a rotary table provided in a circumferential direction.
- a body material application device which is connected to a powder material application device for the lower punch and a powder material application device for the lower punch at a position opposite to the rotation direction of the rotary table.
- the surface on the side facing the rotary table is made a smooth surface, and the coating device for the powder material for the lower punch is equipped with an outer surface, such as a lubricant mixed with air pulsation waves.
- a powder material inlet for feeding the powder material is provided, and the powder material fed into the powder material inlet is Through the through holes provided to penetrate the coating apparatus of the powder material for punch, sent to the surface on the side facing the rotation Te one table, facing the rotary table of the through hole
- the powder discharged together with air from the discharge port on the front side of the surface of the die is contained in the powder material coating device for the lower punch, the inner peripheral surface of the mortar, and to a specified depth.
- the powder material application device for the upper punch penetrates the powder material application device for the upper punch from the surface opposite to the rotary table
- it includes a long slit portion curved so as to follow the rotation trajectory of the plurality of upper punches, and a slit portion region provided on the outer surface side of the powder material application device for the upper punch.
- a punch accommodation groove provided for accommodating a plurality of upper punches rotating and moving, and is provided so as to be curved along the rotation path of the plurality of upper punches. The width of the receiving groove should be equal to or slightly larger than the outer diameter of each of the upper punches.
- the lower surface of the upper punch housed in the upper punch receiving groove is easily exposed to the powder supplied from the slit, while the lower surface of the upper punch is stored in the upper punch receiving groove.
- the powder material is hardly attached to the side circumference of the punch, and the through hole of the powder material for the lower punch is formed through a discharge port on the surface side facing the rotary table.
- the powder material sprayed on the inner peripheral surface of the lower punch and the upper surface of the lower punch inserted to the specified depth, which is contained in the powder material application device for the lower punch together with the air Is further supplied to a slit provided in a powder material application device for the upper punch.
- the air pulsation wave is applied to the upper surface of the lower punch inserted into the mortar to a predetermined position from the outlet of the through hole provided in the powder material application device for the lower punch.
- the mixed powder material is directly sprayed.
- excess powder which easily adheres or accumulates on the upper surface of the lower punch, is blown off from the upper surface of the lower punch by an air pulsating wave.
- the air pulsating wave also blows off excess powder material on the inner peripheral wall, so that the powder material is evenly distributed on the inner peripheral wall of the mortar. Applied.
- the powder material applying device for the upper punch is connected to the powder material applying device for the lower punch in a direction opposite to the rotation direction of the rotary table, and the powder for the lower punch is connected.
- the inner peripheral surface of the mortar which is housed in a powder material application device for the lower punch, together with air, from the discharge port on the surface side of the through hole of the body material facing the rotary table, and The powder material sprayed on the upper surface of the lower punch inserted into the mortar to the predetermined depth further The powder material is supplied to a slit provided in a coating device.
- the excess powder material blown off from the upper surface of the lower punch and / or the inner peripheral wall surface by the air pulsating wave is mixed with the air, and in a state opposite to the rotating direction of the rotating table. (Upstream side) and released from the slit.
- the powder material coating device for the upper punch contains a plurality of upper punches that rotate and move so as to include a long slit region. Because the upper punch receiving groove is provided, the upper punch that moves in the upper punch receiving groove, on the lower surface of the upper punch While moving from the start to the end, the powder material coming from above and below from all over will continue to collide with the lower surface in a substantially vertical direction.
- the powder material adheres to the lower surface of the upper punch, which is hard to adhere due to gravity, with time, so that the powder material adheres to the lower surface of the upper punch.
- the body material can be applied uniformly.
- the configuration is such that the powder mixed with air flows in the direction opposite to the direction of rotation of the rotary table, so that the powder mixed with air flows in the direction of rotation of the rotary table in the forward direction.
- the powder material can be made to efficiently collide with the lower surface of the upper punch 0 as compared with the above-described configuration.
- the powder material applying apparatus can efficiently and uniformly apply the powder material to the lower surface of the upper punch.
- the powder material applying apparatus is arranged such that the powder material applying apparatus according to claim 23 is located above the slit portion of the powder material applying apparatus for the upper punch. Further comprising a suction means, wherein the first suction means has a suction port large enough to cover an area of the slit portion.
- the suction port has a shape along the outer peripheral side of the rotation trajectory of the plurality of upper punches.
- the slit is formed by the shape of the suction port. An air current is generated from the slit to the suction port above the slit, and the powder material dispersed in the air is supplied to the slit uniformly.
- the powder material application device for an upper punch according to claim 8 wherein the powder material application device includes an upper punch material application device that constitutes the powder material application device. Since the first suction means having the same configuration as that of the coating device is provided, the same effect as that of the powder material coating device for the upper punch described in claim 8 can be obtained.
- the powder material application device according to claim 25 is the width of the slit portion of the powder material application device for the upper punch of the powder material application device according to claim 23 or 24.
- the width of the area of the score and the area of the stamp formed on the tablet are made to substantially match.
- the powder material application device for an upper punch according to claim 13, wherein the width of the slit portion of the powder material application device for the upper punch constituting the powder material application device is set in the powder material application device. Similar to the applicator of the first aspect, the width of the area of the dividing line or the mark formed on the tablet is made to substantially coincide with the width of the area. I do.
- the powder material applying device according to claim 26 is the powder material applying device for an upper punch of the powder material applying device for an upper punch according to any one of claims 23 to 25.
- the shape of the slit part of the device is zigzag.
- the powder material applying device for an upper punch according to claim 14 wherein the shape of the slit portion of the powder material applying device for the upper punch constituting the powder material applying device is the same as that of the powder material applying device. Since it has a zigzag shape as in the case of the application device of the first aspect, the same effect as that of the powder material application device for an upper punch according to claim 14 is achieved.
- the powder material applying device is the powder material applying device for an upper punch of the powder material applying device for an upper punch according to any one of claims 23 to 26.
- Mesh means having a predetermined hole diameter was provided above the slit portion of the apparatus.
- a powder material applying device is a discharge port of a powder material applying device for a lower punch of the powder material applying device according to any one of claims 23 to 27. Is provided at a substantially central portion of the upper surface of the lower punch, which is inserted to a predetermined position in a position located immediately below the discharge port, so as to face a substantially vertical direction.
- the powder material application device for a lower punch according to claim 18, wherein an outlet of the powder material application device for a lower punch constituting the powder material application device is provided. Similar to the outlet of the device, the lower punch is inserted to a predetermined position in a position located immediately below the outlet, and is provided substantially in the center of the upper surface of the lower punch so as to be directed substantially vertically. The same effect as that of the powder material application device for lower punches described in 8 can be obtained.
- a powder material applying device is a rotary member of a powder material applying device for a lower punch, wherein the powder material applying device according to any one of claims 23 to 28 is a rotating device.
- the powder material applying device according to any one of claims 23 to 28 is a rotating device.
- the lower punch material powder coating apparatus constituting the powder material coating apparatus is similar to the lower punch powder material coating apparatus according to claim 19. Since the second suction means having the above configuration is further provided, the same effect as that of the powder material applying apparatus for lower punches according to claim 19 can be obtained.
- the apparatus for applying a powder material according to claim 30 is the apparatus for applying a powder material according to claim 29, wherein the second suction means is provided on a rotary table. It has a slit-shaped suction port long enough to cover each of the plurality of dies and the periphery thereof so as to be orthogonal to.
- the lower punch according to claim 20 wherein the powder material application device includes a suction port of a second suction unit provided in the powder material application device for the lower punch constituting the powder material application device.
- the lower punch according to claim 20 which has a configuration similar to that of the powder material application device for The same effect as that of the powder material coating device for use can be obtained.
- the suction port of the second suction means of the powder material coating apparatus according to claim 30 is provided with at least the discharge port.
- a plurality of said diameters provided on the rotary table from a position at which the rotary table is located.
- the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface of the die, of the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface is put into the die.
- the place where the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface of the lower punch inserted to the predetermined position is a place where it does not conduct, and it is suctioned and removed.
- Excess powder material in the upper surface of the lower punch and the inner peripheral wall of the die can be removed by suction.
- the powder material coating apparatus according to claim 32 is the powder material coating apparatus for lower punches according to any one of claims 23 to 31.
- the molding material adhering to the front surface of the discharge port on the surface facing the rotating tape of the coating device, and further to the upper surface of the lower punches, the inner walls and the outer periphery, is sequentially removed.
- a third suction means provided with a molding material suction port that is substantially orthogonal to the rotation orbits of the plurality of dies.
- the powder material coating apparatus for lower punches constituting the powder material coating apparatus is the same as the powder material coating apparatus for lower punches according to claim 22. Since the third suction means is provided, the same effect as the powder material application device for lower punches according to claim 22 can be obtained.
- the powder material application device is a slit portion of the powder material application device for an upper punch of the powder material application device according to any one of claims 23 to 32. Instead, on the bottom surface of the upper punch receiving groove, on the lower surface of multiple upper punches moving in the upper punch receiving groove along the rotation path of the multiple upper punches, the powder dispersed in the air current of the air pulsating wave A plurality of injection holes for spraying the material were arranged.
- the slit portion of the powder material coating device for the upper punch is replaced. Instead, on the bottom surface of the upper punch receiving groove, the powder material dispersed in the air current of the air pulsating wave is Because of the arrangement of multiple spray holes, the powder material is sprayed from each of the multiple spray holes.
- the powder material hardly adheres due to the gravity, and the powder material is uniformly applied to the lower surface of the upper punch.
- the powder material applying apparatus according to claim 34 is a rotary apparatus for the powder material applying apparatus for lower punches of the powder material applying apparatus according to any one of claims 23 to 33.
- An application unit for the powder material for the upper punch is connected at a position in the forward direction, not in the direction opposite to the rotation direction of the table.
- the powder material coating device for the lower punch which constitutes the powder material coating device, is provided with the powder material for the upper punch at a position in the rotation direction and the forward direction of the rotary table. Since the coating device is connected, the rotating direction of the rotary table and the powder material for the lower punch are supplied from the powder coating device for the upper punch to the powder material coating device for the upper punch. Since the flow direction is the same, the powder material can be applied to the lower surface of the upper punch with low resistance and in a quiet state (under a negative pressure atmosphere).
- Claim 35 specifies an external lubricating tablet press.
- the rotary table can be rotated at a predetermined position on a rotary table provided with a plurality of days in a circumferential direction of the continuous tablet press.
- the powder material application device according to any one of claims 11 to 34 is fixedly attached.
- the powder according to any one of claims 11 to 34 is provided at a predetermined position (lubricant spray point) of a conventional tablet press such as a rotary tablet press.
- a lubricant is used as the powder material, the punch does not produce a squeak and a tableting failure.
- the surface modifier is The tablet can be manufactured using this external lubricating tableting machine using a punch and a surface to which the surface modifier has been evenly applied, so that the surface modifier can be applied to the surface of the tablet.
- This external lubricated punching machine capable of producing tablets with uniform coating.
- FIG. 1 is an overall configuration diagram schematically showing an example of an external lubricating tableting machine according to the present invention.
- FIG. 2 shows the rotary table of the open-type tableting machine that constitutes the external lubricating tableting machine shown in Fig. 1, the coating device for the powder material for the upper punch, and the powder material for the lower punch.
- FIG. 3 is a plan view schematically showing an arrangement of a coating device.
- FIG. 3 is a schematic developed view in which the rotary table shown in FIG. 2 is cut and developed between a molding material filling point and a lubricant applying point.
- FIG. 4 is a diagram schematically showing a powder material application device for the upper punch
- FIG. 4 (a) is a powder material application device for the upper punch
- Fig. 4 (b) is a schematic cross-sectional view taken along the line IV-IV in Fig. 4 (a), which is provided in the vicinity of the powder material application device for the upper punch. The suction duct is shown together.
- FIG. 5 is a perspective view schematically showing the shape of the suction duct centered on the suction port.
- FIG. 6 is a diagram schematically illustrating a powder material application device for a lower punch.
- FIG. 6 (a) is a perspective view taken along line II-II in FIG.
- FIG. 6 (b) is a schematic cross-sectional view taken along the line VI-VI in FIG. 6 (a)
- FIG. 6 (c) is a state in which a certain time has elapsed from the state shown in FIG. 6 (b). It is sectional drawing which shows schematically.
- FIG. 7 is a cross-sectional view schematically showing a VII portion in FIG. 1 in a further enlarged manner.
- FIG. 8 is a plan view schematically showing an elastic film body.
- Fig. 9 is a plan view schematically showing the position of the air pulsation wave introduction port provided in the dispersion chamber when the dispersion chamber is viewed in plan.
- Fig. 9 (a) shows the ideal installation of the air pulsation wave introduction port.
- FIG. 9B is a view for explaining the position
- FIG. 9B is a view for explaining a practically possible mounting position of the air pulsation wave introduction port 55a.
- Fig. 10 is a diagram schematically illustrating the positional relationship between the air pulsation wave introduction port and the discharge outlet provided in the dispersion chamber when the dispersion chamber is viewed in a plan view
- Fig. 10 (a) shows the air pulsation wave conduction.
- FIG. 10 is a view for explaining a substantially possible positional relationship between an inlet and an outlet
- FIG. 11 is an explanatory diagram schematically illustrating a phenomenon that occurs in the elastic film when an air pulsation wave is sent into the dispersion chamber.
- FIG. 12 is a cross-sectional view schematically showing an air pulsation wave generator suitable for the present invention.
- FIG. 13 is a plan view schematically showing another example of a powder material applying device for a lower punch according to the present invention.
- FIG. 14 is an overall configuration diagram schematically showing another example of the external lubricating tableting machine according to the present invention.
- FIG. 15 shows the rotary table of the rotary tableting machine that constitutes the external lubricating tablet press shown in Fig. 14, a powder material coating device for the upper punch and a powder material coating device for the lower punch.
- FIG. 4 is a plan view schematically showing the arrangement of the components.
- FIG. 16 is a schematic developed view in which the rotary table shown in FIG. 15 is cut and developed between a molding material filling point and a lubricant application point.
- FIG. 17 is an overall configuration diagram schematically showing an example of an external lubricating tableting machine provided with the powder material application device according to the present invention.
- FIG. 18 is a plan view schematically showing an arrangement of a rotary table and a powder material coating device of the rotary tableting machine constituting the external lubricating tableting machine shown in FIG.
- FIG. 19 is a schematic developed view in which the rotary table shown in FIG. 17 is cut and developed between the molding material filling point and the lubricant application point.
- FIG. 20 is a plan view schematically showing an apparatus for applying the powder material.
- FIG. 21 is a schematic sectional view taken along the line XXI—XXI in FIG.
- FIG. 22 is a schematic sectional view taken along the line XXII-XXII in FIG.
- FIG. 23 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
- FIG. 24 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
- FIG. 25 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
- FIG. 26 is a schematic sectional view taken along the line XXVI-XXVI in FIG.
- Fig. 27 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
- FIG. 28 is a schematic cross-sectional view along the line XXVIII—XXVIII in FIG.
- FIG. 29 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
- FIG. 30 is a schematic sectional view taken along line XXX-XXX in FIG.
- FIG. 31 is a line graph showing the correlation between the spray amount and the elapsed time of the powder material discharging device used in the external lubricating tableting machine according to the present invention.
- FIG. 32 shows that in the powder material discharging device used in the external lubricating tablet press according to the present invention, the amount of the powder material stored in the powder material storage chamber affects the spray amount.
- 4 is a line graph showing a correlation between a spray amount and an elapsed time.
- FIG. 33 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
- FIG. 34 is a process chart schematically showing a method for producing a tablet using a conventional external lubricating tableting machine described in Japanese Patent Publication No. 56-14098.
- Fig. 35 schematically shows a main part of a conventional external lubricating tableting machine described in Japanese Patent Application Laid-Open No. 7-124234 and already proposed by the present inventors. It is a block diagram.
- FIG. 36 is a diagram schematically showing an air pulsation wave
- FIG. 36 (a) shows an air pulsation wave in which a mountain has a positive pressure and a valley has an atmospheric pressure
- FIG. Each of the peaks and the valleys exemplifies a positive pressure air pulsation wave.
- a powder material application device for an upper punch and a powder material application device for a lower punch are separately provided, and these are provided on a rotary table of a tableting machine. An example provided at another position will be described.
- FIG. 1 is an overall configuration diagram schematically showing an example of an external lubricating tableting machine according to the present invention.
- the external lubricating tableting machine 1 is composed of a rotary tableting machine 2, a powder material coating device 3 for an upper punch, a powder material coating device 4 for a lower punch, and a powder material for an upper punch.
- a powder material discharge device (quantitative feeder) 5 that supplies the powder material to each of the body material coating device 3 and the powder material coating device 4 for the lower punch, and an air source 7 such as a blower And an air pulsation wave generator 8 that converts compressed air generated by driving the air source 7 into a positive pressure air pulsation wave.
- a member device denoted by reference numeral 10 denotes a computing device for controlling the entire operating environment of the external lubricating tableting machine 1.
- a member device denoted by reference numeral 11 denotes a first device such as a blower. This shows the suction means.
- the member indicated by T1 is a pipe connecting the air source 7 and the air pulsation wave generator 8, and the member indicated by ⁇ 2 is an air pulsation wave generator 8 and a powder material discharge device (quantitative filter).
- the pipes that connect to 5) and the members indicated by ⁇ 3 are the powder material discharge device (quantitative feeder) 5, the powder material application device 3 for the upper punch, and the powder for the lower punch. Pipes connecting each of the material coating devices 4 are shown.
- the member indicated by reference numeral 4 indicates a suction duct connected to the first suction means 11.
- a flow control device 12 is connected in the middle of the pipe T1 so that the flow control device 12 can adjust the flow rate of the compressed air generated by driving the air source 7.
- the pipe ⁇ 3 is led out from the powder material discharge device (quantitative feeder) 5 as one pipe, and branches along the way into two pipes T3a and T3b to form a pipe T3.
- a is connected to the powder material coating device 3 for the upper punch
- the pipe T 3 is connected to the powder material coating device 4 for the lower punch.
- Each of the two pipes T 3a and T 3b has a flow control valve v 1 such as a solenoid valve, v 2 is provided for each.
- a flow control valve V3 such as a solenoid valve is provided in the middle of the suction duct T4.
- members indicated by C1 indicate signal lines for exchanging signals between the arithmetic unit 10 and each of the flow control device 12 and the air pulsation wave generator 8, and the flow control device 12
- Each of the air pulsation wave generator 8 and the air pulsation wave generator 8 operates based on the control signal of the arithmetic unit 10.
- C 2 indicates a signal line for exchanging signals between the arithmetic unit 10 and the flow control valve vl.
- the flow control valve vl opens and closes based on the control signal of the arithmetic unit 10. The amount can be controlled to a predetermined opening / closing amount.
- C 3 indicates a signal line for exchanging signals between the arithmetic unit 10 and the flow control valve vl, and the flow control valve V 2 controls the flow of the signal based on the control signal of the arithmetic unit 10.
- the opening / closing amount can be controlled to a predetermined opening / closing amount.
- C 4 indicates a signal line for exchanging signals between the arithmetic unit 10 and the flow control valve V 3, and the flow control valve v 3 is based on a control signal of the arithmetic unit 10,
- the opening / closing amount can be controlled to a predetermined opening / closing amount.
- FIG. 2 shows the rotary table 21 of the lip-type tableting machine 2 that constitutes the external lubricating tableting machine 1, the applicator 3 for the powder material for the upper punch, and the powder material for the lower punch.
- FIG. 3 is a plan view schematically showing an arrangement of a coating device 4, and FIG. 3 shows a rotary table 21 shown in FIG. 2 between a molding material filling point P 2 and a lubricant applying point P 1. A schematic development view cut and expanded is shown.
- the one-shot tablet press 2 is provided with a plurality of rotary tables 21 provided in the circumferential direction and rotatably provided, and a rotary table 21 that rotates in synchronization with the rotation of the rotary table 21. , And a plurality of lower punches 24 that are rotated in synchronization with the rotation of the turntable 21.
- the lubricant spray point P1 is divided into two parts, a lubricant spray point P1a for the upper punch and a lubricant spray point P1 for the lower punch.
- a powder material application device 3 for the upper punch is installed at the lubricant spraying point P 1 a for the upper punch, and a lubricant spraying point P lb for the lower punch is used for the lower punch. It is characterized in that a powder material coating device 4 is installed.
- the upper surface S 24 of the lower punch 24 is located at the lowest position in the mill 22.
- the upper surface S 24 of the lower punch 24 is the lowest position in the mortar 22, the upper surface S 24 of the lower punch 24 and the inner peripheral wall surface of the lower die 22 (the inner peripheral wall surface of the mortar 22) The inner surface of the upper surface of the lower punch 24 above the inner surface of the lower punch 24)
- the powder material is applied to S22, and when the molding material is compression-molded, the die 2 that comes into contact with the molding material is pressed. Since the powder material is applied evenly to the inner peripheral wall S22 of No.2, the molding material does not adhere to the mortar 22 when manufacturing the tablet. The same applies to the second embodiment of the invention described below.
- the powder material applying device 3 for the upper punch includes a connection plate 3 Op.
- the connection plate 3 Op is provided for facilitating the piping of the powder material for the upper punch to the coating device 3, and is provided so as to protrude outward from the turntable 21.
- connection ports e8 and e9 described later are provided on its upper surface.
- the powder material applying device 4 for the lower punch includes a connection plate 4 Op.
- the connection plate 40 p is provided for facilitating the piping of the powder material for the lower punch to the applicator 4, and is provided so as to protrude outward from the rotary table 21.
- a powder material introduction port e1 and a discharge port e5 described later are provided on the upper surface.
- FIG. 4 is a view schematically showing a powder material application device 3 for the upper punch
- FIG. 4 (a) is a powder material application device 3 for the upper punch
- Fig. 4 (b) is a schematic cross-sectional view taken along the line IV-IV in Fig. 4 (a).
- the suction duct T4 provided at the bottom is also shown.
- the powder material application device 3 for the upper punch uses a plurality of upper punches 2 3... It is located below the orbit (Or).
- the powder material application device 3 for the upper punch is provided so as to be in contact with the rotary table 21 as long as it is provided below the rotation path Or of the plurality of upper punches 2 3. 3 may be provided above the turntable 21 as shown in FIG.
- the powder material application device 3 for the upper punch is provided at a front stage of the molding material filling point P2 as shown in FIG.
- the powder material application device 3 for the upper punch is composed of an inner peripheral wall S 22 of the die 22 into which a pair of lower punches 24 are inserted to a predetermined position and an upper surface of the lower punch 24.
- a plurality of upper punches 2 3 are provided so as to be curved along the rotation trajectory Or of the upper punches 2 3.
- the upper punches are sequentially accommodated, and are provided on the bottom surface of the long upper punch receiving groove 31 and the upper punch receiving groove 31 along the rotation path Or of the plurality of upper punches 23.
- the lubricant powder L dispersed in the pulsating air current is sprayed on the lower surface S2 3 of the upper punches 2 3 moving inside the upper punch receiving groove 3 1 And a slit portion 32 to be formed.
- the upper punch receiving groove 31 is provided so as to be curved along the rotation path Or of the plurality of upper punches 23.
- the width W 3 1 of the upper punch grooving groove 3 1 is set to be equal to or slightly larger than the outer diameter of each of the plurality of upper punches 2 3.
- the lower surface S 23 of the upper punch 23 accommodated in the upper punch 23 is easily exposed to the lubricant powder L supplied from the slit portion 32, while being accommodated in the upper punch receiving groove 31.
- the lubricant powder L is hardly attached to the periphery of the upper punch 23.
- reference numeral 33 denotes a lubricant powder supply hole for supplying the lubricant powder L dispersed in the air current of the air pulsating wave to the slit portion 32.
- the lubricant powder supply hole 33 is located on the connection plate 3 Op shown in FIG. It is connected to the connection port e8 provided on the surface.
- a suction port T4a of a suction duct T4 of the first suction means 9 is further provided above the slit portion 32, as shown in FIGS. It has been done.
- FIG. 5 is a perspective view schematically showing the shape of the suction port T4a of the suction duct T4 centered on the suction port T4a.
- the suction port T4a has a size to cover the area of the slit portion 32, and has a shape along the outer peripheral side of the rotation trajectory Or of the plurality of upper punches 23 in plan view. You are.
- a large space is formed inside the suction port T4a, and a suction duct T connected to the first suction means (the first suction means 11 shown in FIG. 1) is formed in the deep space. It has a structure in which a pipe T5 connected to 4 is provided.
- e indicates a connection port of the pipe T5.
- the connection port e 9 is connected to the first suction means (the first suction means 11 shown in FIG. 1). It is provided on the upper surface of the connection plate 30p for easy connection.
- the upper punch 23 moves in the upper punch receiving groove 31, and each of the upper punches 23 is placed on the lower surface S23 of the upper punch 23. While sequentially moving from the starting end es of the slit portion 32 to the end portion ee, the lubricant powder L which is sprayed from the slit portion 32 and is mixed with and dispersed in the airflow of the positive pressure air pulsating wave is dispersed. Riding on the airflow from the slit portion 32 toward the suction port T4a, collides upward in a substantially vertical direction from below and continues to adhere.
- the application time of the powder material to the lower surface S23 of each of the upper punches 23 is determined by the application time of the powder material to the upper surface S24 of the lower punch 24 and the inner peripheral wall surface 22 of the lower punch 22.
- the time is set to “1”
- the powder material on the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the mill 22 is
- the coating time is preferably 1 to 50 times, more preferably 5 to 40 times the coating time.
- the width W32 of the slit portion 32 is made to substantially match the width of the area of the score line or the mark formed on the tablet t.
- the powder material applying device 3 for the upper punch is used, the lower surface S 23 of each of the upper punches 23, a portion forming a score line or a mark on the tablet t, That is, since the lubricant powder L can be applied evenly to the portion where the complex unevenness is formed, the lower surface S 2 3 of the upper punch 2 3 Tablets can be manufactured without causing tableting obstacles such as laminating, caving, and sticking in the portions where such complex irregularities are formed.
- a concave portion (shown by a broken line in FIG. 2 as viewed in a plan view) is formed on the back surface of the coating device 3 (the surface facing the surface of the rotating table 21).
- a generally right-angled triangular recess 3c) is provided.
- the conduit T5 is branched into two branch pipes T5a and T5b, one branch pipe T5a is connected to the suction port T4a side, and The branch pipe T5b is connected to the recess (represented by a broken triangle 3c in a right-angled triangle when viewed in a plan view as indicated by a broken line in FIG. 2).
- the suction port T4a goes into the suction port T4a.
- the suction port T4a goes into the suction port T4a.
- the air flow of the suction atmosphere is generated, it is formed on the surface of the rotary table 21, for example, in a recess (shown by a broken line in FIG. 2, when viewed in a plan view, a generally triangular recess 3c).
- a material or a powder material in this example, a lubricant powder
- a molding material or a powder material in this example, a lubricant
- FIG. 5 is merely an example, and the suction port T4a and the recess (shown by a broken line in FIG. 2, when viewed in a plan view, are generally right-triangular-shaped recesses 3c) are the connection ports.
- the suction port T 4 a By driving the first suction means 11 connected to the e 9, the suction port T 4 a is connected to the air flow of the suction atmosphere flowing into the suction port T 4 a, and the recess (shown by a broken line in FIG. 2).
- a generally triangular-shaped recess 3 c is drawn into the recess (shown by a broken line in FIG.
- connection port e 9 is connected to a recess (represented by a broken line in FIG. 2, which is generally a right triangle-shaped recess 3 c when viewed in a plan view),
- a suction atmosphere shown by a broken line in Fig. 2, when viewed in a plan view
- a suction atmosphere can be generated in the suction atmosphere toward the generally right triangle-shaped recess 3c).
- suction means 11 When the first suction means 11 is connected to a connection port (not shown) connected to the suction port T4a, and the first suction means 11 is driven, suction is performed on the suction port T4a. Needless to say, it may be possible to generate an airflow of a suction atmosphere toward the mouth T4a.
- FIG. 6 is a diagram schematically illustrating a powder material application device 4 for a lower punch
- FIG. 6 (a) is a perspective view taken along the line II-II in FIG. (b) is a schematic cross-sectional view taken along the line VI-VI in FIG. 6 (a)
- FIG. 6 (c) is a state after a certain time has elapsed from the state shown in FIG. 6 (b). It is sectional drawing which shows schematically.
- the powder material application device 4 for the lower punch is fixed on the rotary table 21 so that the rotary table 21 can slide on the rotary table 21 as shown in FIGS. 6 (a) to 6 (c). It is located in
- the surface S 4 a of the coating device 4 on the side facing the rotary table 21 is made a smooth surface so that the rotary table 21 can slide. It is preferable that the surface S 4 a of the coating device 4 on the side facing the rotary table 21 is in contact with or close to the surface of the rotary table 21.
- the surface S 4 a of the coating device 4 on the side facing the rotary table 21 is, when approaching the surface of the rotary table 21, a surface S 4 a on the side facing the rotary table 21.
- the gap between the surface S4a of the coating device 4 on the side facing the rotary table 21 and the surface of the rotary table 21 is preferably 100 / m or less. It is more preferably 5 O ⁇ m or less, particularly preferably 30 m or less. As described above, when the gap between the surface S4a of the coating device 4 on the side facing the rotary table 21 and the surface of the rotary table 21 is reduced, the powder material passes through the gap. However, the phenomenon of scattering can be prevented.
- a powder material inlet e 1 for feeding the lubricant powder L mixed with the air pulsating wave is provided.
- the pipe T 3 b is connected to the powder material inlet e 1.
- the lubricant powder L sent from the powder material inlet e 1 passes through the through hole h 1 provided to penetrate the device 4, and the surface S 4 a on the side facing the rotary table 2. Is sent to the discharge port e2 provided in the
- Slip is sent to the surface S 4 a on the side facing the rotary table 21 and is discharged with air from the outlet e 2 on the side S 4 a of the through hole hi on the side facing the rotary table 21.
- the powder powder L is accommodated below the device 4, the inner peripheral wall S 22 of 22, and the upper surface S 2 of the lower punch 24 inserted into the mortar 22 to a predetermined depth. 4 is designed to be sprayed in a substantially vertical direction at the center (see Fig. 6 (b)).
- this device 4 is sprayed from a discharge hole e2 of a through hole h1 to a lower punch 24 and a box 22 which are housed below the device 4, and a lower punch 24 and a mill 22
- a second suction means such as a blower (not shown) for removing the lubricant powder L that is attached to the rotary table and the excess lubricant powder L on the turntable 21; ) Is connected I have.
- e5 indicates a connection port to which the second suction means (not shown) is connected.
- the suction port h5 of the second suction means has a plurality of rotating orbits (see FIG. 6 (a), a slit-like shape that is substantially perpendicular to the rotation orbit O r) indicated by the dashed line, and that is long enough to cover each of the plurality of dies 2 2 have.
- the lubricant powder L which is extraly attached and deposited, is added to the inner peripheral wall S22 of the upper surface S24 of the punch 24 and the lower peripheral surface S22 where the lower punch 24 is inserted to a predetermined position. Since it can be removed, excess lubricant powder L adheres to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 24 into which the lower punch 24 has been inserted to a predetermined position. Without depositing on these surfaces, lubricant powder And summer so that L can be uniformly applied. Further, even if the lubricant powder L adheres and accumulates around the rotary table 21, the second suction means (not shown) drives the suction port h 5. Thus, the lubricant powder L can be removed.
- an external lubricating tablet which does not contain the lubricant powder L therein can be efficiently produced.
- the distance L (e 2-h 5) between the outlet e 2 and the suction port h 5 is set to be longer than at least the diameter D 22 of 22.
- the second suction means (not shown) is used.
- the suction port h5 of,- is separated from at least the position of the discharge port e2 by a diameter D22 of each of a plurality of 22. (L (e2-h5)> D22).
- the powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the die 22 in this example, In the powder L
- excess powder material in this example, the lubricant powder L
- the air pulsation wave was dispersed on the upper surface S 24 of the lower punch 24 inserted into the mortar 22 to the position where it was run.
- the powder material in this example, the lubricant Powder L
- FIG. 7 is a sectional view schematically showing a VII portion in FIG. 1 in a further enlarged manner.
- the powder material discharge device 5 includes a powder material storage chamber 53 connected via a powder material cut-out valve 52 below the hopper 51, and a powder material storage chamber 53 below the powder material storage chamber 53.
- An elastic membrane 54 provided and a b dispersion chamber 55 connected below the powder material storage chamber 53 via the elastic membrane 54 are provided.
- FIG. 8 is a plan view schematically showing the elastic membrane 54.
- the elastic membrane 54 has a hole (slit) 54a at the center thereof.
- the powder material storage chamber 53 is made of glass or a resin such as an acrylic resin, and has optical transparency. As shown in FIG. 7, the powder material storage chamber 53 is provided with a level sensor 56 for detecting the amount of the lubricant powder L stored in the powder material storage chamber 53. ing.
- the level sensor 56 includes a light emitting element 56 a that emits light such as infrared light, and an optical element 56 b that receives light emitted from the light emitting element 56 a.
- the light emitting element 56 a and the light receiving element 56 b are arranged to face each other with the powder material storage chamber 53 interposed therebetween.
- the lubricant powder L stored in the powder material storage chamber 53 The amount can be detected.
- the amount of the lubricant powder L stored in the powder storage chamber 53 is the position where the level sensor 156 is provided (the height of the position where the level sensor 156 is provided from the elastic membrane 54) H
- the light emitted from the light emitting element 56a hits the lubricant powder L and cannot be received by the light receiving element 56b (turns off).
- the powder material is stored. It can be detected that the height H of the lubricant powder L in the chamber 53 from the elastic membrane 54 exceeds the height Hth (H> Hth).
- the amount of the lubricant powder L stored in the powder material storage chamber 53 is determined by the position where the level sensor 56 is provided (the height of the position where the level sensor 56 is provided from the elastic membrane 54) H th When the value is less than 5, the light emitted from the light emitting element 56a can be received by the light receiving element 56b (turned on). At this time, the lubricant powder L in the powder material storage chamber 53 is used. Height H from the elastic membrane 54 is less than the height H th
- the powder material extraction means (powder material extraction valve) 52 moves up and down according to the detection value of the level sensor 56 to close or open the discharge port 51 a of the hopper 51. It is now possible to use it.
- the powder material cutting means 52 when the detection value of the level sensor 56 is turned off, the powder material cutting means 52 is moved upward, and the discharge port 5 la of the hopper 51 is closed, When the detection value of the level sensor 5 6 is turned on, the powder material cutting means 52 is moved downward to open the discharge port 51 a of the hopper 51, and the powder material storage chamber 5 is opened.
- an approximately constant amount of lubricant powder L is always stored.
- the shape of the dispersion chamber 55 is substantially cylindrical so that a swirling flow is easily generated in the dispersion chamber 55.
- the shape of the dispersion chamber 55 is substantially cylindrical, the shape of the dispersion chamber 55 is not particularly limited as long as a swirling flow can be generated in the dispersion chamber 55.
- the dispersion chamber 55 is provided with an air pulsation wave introduction port 55a for sending an air pulsation wave in a position substantially below the dispersion chamber 55 in a direction substantially tangential to the inner peripheral surface of the dispersion chamber 55.
- an outlet 55b for discharging the powder material mixed, dispersed, and fluidized into the air from the dispersion chamber 55.
- FIG. 9 is a plan view schematically showing the position of the air pulsation wave introduction port 55a provided in the dispersion chamber 55 when the dispersion chamber 55 is viewed in a plan view.
- FIG. 9 (a) shows the air pulsation wave introduction port 55.
- FIG. 9B is a diagram illustrating an ideal mounting position of a, and FIG. 9B is a diagram illustrating a substantially possible mounting position of the air pulsation wave introduction port 55a.
- the curved arrows indicate the direction of the air pulsating wave swirling flow generated in the dispersion chamber 55.
- the air pulsation wave introduction port 55a is preferably provided in the tangential direction of the dispersion chamber 55 as shown in FIG. 9 (a).
- the air pulsation wave introduction port 55a does not need to be strictly provided in the tangential direction of the dispersion chamber 55 as shown in FIG. 9 (a), and one dominant swirling flow flows in the dispersion chamber 55.
- a pulsating wave introduction port 55a may be provided.
- FIG. 10 is a diagram schematically illustrating the positional relationship between the air pulsation wave inlet 55a and the outlet 55b provided in the dispersion chamber 55 when the dispersion chamber 55 is viewed in a plan view
- FIG. FIG. 10 is a view for explaining a substantially possible positional relationship between the air pulsation wave introduction port 55a and the discharge port 55b
- FIG. 10 (b) shows a preferred relationship between the air pulsation wave introduction port 55a and the discharge port 55b. It is a figure explaining a positional relationship.
- the arrow indicated by a curve schematically indicates the direction of the swirling flow of the air pulsation wave generated in the dispersion chamber 55.
- the discharge port 55b1 or the discharge port 55b2 is exemplified in FIG. 10 (b).
- the discharge port 55b is provided in the forward direction with the direction of the swirling flow of the air pulsation wave generated in the dispersion chamber 55 (the traveling direction of the air). preferable.
- an air pulsation wave generator 7 is connected to the air pulsation wave introduction port 55a of the dispersion chamber 55 via a pipe T2.
- the outlet 55b is connected to the powder material inlet 33 of the powder material applying device 3 for the upper punch and the powder material inlet 33 of the powder material applying device 4 for the lower punch via the pipe T3. Connected to 1.
- a member device indicated by 57 is imaging means such as a CCD camera provided to confirm the operation of the powder material cutting means 52, and a member device indicated by 58 is light such as a laser beam. , And receives the scattered light scattered by the lubricant powder (not shown) falling from the outlet 5 la of the hopper 51, so that the lubricant falls from the outlet 51 a of the hopper 51. A sensor for checking the state of the powder (not shown).
- the member device shown at 59 irradiates light such as a laser beam,
- a member device indicated by 60 indicates a repel sensor configured to include a light emitting element 60a and a light receiving element 6Ob.
- the level sensor 60 is used to control the hopper 5a. The remaining amount of the powder material in 1 is detected.
- each of the powder material application device 3 for the upper punch and the powder material application device 4 for the lower punch is mixed with air, dispersed, and fluidized lubricant.
- Agent powder
- lubricant powder L is stored in hopper 51, and rail sensor 56 is activated.
- the powder material cutting means 52 is opened, and the lubricant powder L is dropped into the powder material storage chamber 53.
- Lubricant powder L falls and accumulates in the powder material storage chamber 53, and the height H of the lubricant powder L accumulated in the powder material storage chamber 53 from the elastic film 54 increases to the level.
- the height exceeds the height H th of the position where the sensor 56 is provided, light such as infrared rays emitted from the light-emitting element 56 a emits lubricant powder L deposited in the powder material storage chamber 53.
- the light receiving element 56 b is turned off because the light receiving element 56 b cannot receive the light emitted from the light emitting element 56 a.
- the powder material cutting means 52 is automatically closed, the lubricant powder L is stored from the elastic membrane 54 to a height Hth which is approximately equal to a predetermined height ( H2Hth).
- the air source 7 is driven, the flow controller 12 is adjusted using the computing unit (controller) 9, and the driving source m of the air pulsation wave generator 8, such as a motor, is moved at a desired speed. As a result, a positive pressure air pulsation wave is generated in the pipe T2.
- air pulsation waves are sent to a position below the dispersion chamber 55 in the tangential direction of the inner peripheral surface of the dispersion chamber 55 or in a direction equivalent thereto.
- a wave introduction port 55a is provided, and at the position above the dispersing chamber 55, on the inner peripheral surface of the dispersing chamber 55, and in the dispersing chamber 55, the progress of swirling air pulsating waves As shown in Fig. 7, the air pulsation wave sent into the dispersion chamber 55 from the air pulsation wave introduction port 55a has a discharge port 55b in the forward direction.
- an air pulsation wave of a swirling flow (a tornado-like swirl flow) from the air pulsation wave introduction port 55a to the discharge port 55b, going upward from below.
- the elastic membrane 54 vibrates according to the frequency, amplitude, and waveform of the air pulsation wave.
- FIG. 11 is an explanatory diagram schematically illustrating a phenomenon that occurs in the elastic membrane 54 when an air pulsation wave is sent into the dispersion chamber 55.
- the elastic membrane 54 becomes elastic as shown in FIG. 11 (a). It deforms and curves upward.
- the upper side of the hole (slit) 54 a is in a V-shaped state in which the upper side is opened, and the slip stored in the powder material storage chamber 53 is in a portion where the slit 73 a is opened. A part of powder powder L falls.
- the air pulsating wave sent into the dispersion chamber 55 transitions from a peak to a valley and the pressure in the dispersion chamber 55 decreases, it elastically deforms and is elastically curved upward.
- the body 54 returns to its original state by restoring force.
- the lower part of the hole (slit) 54a is in an inverted V-shape, and?
- the lubricant powder sandwiched between the slits 54 a falls into the dispersion chamber 55.
- the lubricant powder L that has fallen into the dispersion chamber 55 mixes with the air pulsating wave swirling in the mixing chamber 55, disperses and fluidizes, and flows with air from the discharge port 55b. Is sent out to the pipe T3. .
- the frequency, amplitude, and waveform of the elastic film 54 are determined and vibrated according to the frequency, amplitude, and waveform of the air pulsation wave, only the frequency, amplitude, and waveform of the air pulsation wave are controlled. Therefore, there is an advantage that a certain amount of powder material can be stably supplied together with air into the pipe T3.
- the dispersion chamber 55 since a swirling flow is generated in the dispersion chamber 55 from the lower side to the upper side, the dispersion chamber 55 has a sizing function similar to a cyclone. As a result, the large particles that are not broken by the swirling flow stay at the lower position in the dispersion chamber 55 until they are crushed to a predetermined particle size. It is not fed into each of the material application device 3 and the powder material application device 4 for the lower punch.
- a substantially constant amount of the lubricant powder L can be constantly and continuously discharged, and the lubricant powder L has a uniform particle size, and can be discharged from the discharge port 55b. .
- the air pulsation wave introduction port 55a is provided below the dispersion chamber 55, and the discharge port 55b is provided above the distribution chamber 55.
- the inlet 55a and the outlet 55b do not face each other.
- the air pulsation wave sent from the air pulsation wave introduction port 55a does not directly enter the discharge port 55b, but always enters the discharge port 55b after turning inside the dispersion chamber 55. Therefore, the air pulsation wave can be effectively used in the dispersion chamber 55.
- the discharge port 55b is provided on the inner peripheral surface of the dispersion chamber 55, the lubricant dropped from the hole (slit) 54a of the elastic membrane 54 at the discharge port 55b. There is no phenomenon that the powder L directly enters the discharge port 55b without being mixed with air.
- the powder material storage chamber 53 is provided with a level sensor 56 for detecting the amount of the lubricant powder L stored in the powder material storage chamber 53.
- the hopper 51 is connected above the powder storage chamber 53 with the powder material cutting means 52 interposed, and if the detection value of the level sensor 56 turns off, the powder material cutting means 5 2 is closed and when the detection value of the level sensor 5 6 is turned on, the powder material cutting means 52 is opened, and an approximately constant amount of the lubricant powder L is always stored in the powder material storage chamber 53. They are being stored.
- the sensor using the level sensor 56 has been described as a sensor. However, this is merely a preferred example, and the level sensor 56 in the powder material storage chamber 53 is described. As long as the amount of the lubricant powder L can be detected, various sensors such as a weight sensor can be used.
- an air pulsation wave generator 8 a constant pressure compressed air generated by an air source 7 such as a compressor or a blower is opened and closed by an electromagnetic valve to generate an air pulsation wave, or generated by the air source 7.
- the compressed air at a constant pressure is supplied from the air inlet into a predetermined case, and a rotatable one-way valve is provided in the case to open and close the discharge port provided in the case. Alternatively, it may be generated by rotating a mouth-type valve body.
- the pulsating air pulsation generated by such a method can cause the powder to efficiently mix, disperse, and fluidize the air depending on the physical properties of the powder material, and generate air pulsations having a desired 3 ⁇ 43 ⁇ 4, amplitude, and period. There is a problem that it is difficult to generate waves.
- FIG. 12 is a sectional view schematically showing such an air pulsation wave generator.
- the air pulsation wave generator 8 includes a valve chamber 86 provided with a valve seat 83 between an input port 81 and an output port 82, and a valve body 86 opened and closed by a cam mechanism 85.
- the cam mechanism 85 includes a rotating cam 87 rotatably provided by a driving means (not shown) such as a motor or the like, and a roller 88 attached to a lower end of the valve body 86.
- the valve seat 83 is formed into a hole with a shape that is tapered in the direction of the output port 82, and the valve element 86 is formed into a tapered inverted mortar shape that matches the shape of the valve seat 83.
- the valve seat 83 can be airtightly closed.
- the shaft portion 86a of the valve body 86 is provided in the shaft hole 89h of the case body 89 so as to be free of air and to be vertically movable.
- the roller 88 is rotatably sandwiched by the rotating cam 87, and by rotating the rotating cam 87, the roller 88 moves up and down while rotating according to the uneven pattern provided on the rotating cam 87. It works.
- the rotating cam 87 includes an inner rotating cam 87a and an outer rotating cam 87b.
- Each of the inner rotating cam 87a and the outer rotating cam 87b is provided with a concave / convex pattern so as to keep a gap between the apertures 88 and align with each other.
- the roller 88 is sandwiched between the inner rotating cam 87a and the outer rotating cam 87b, and by rotating the rotating cam 87 without causing splash on the valve body 86, In accordance with the concave / convex pattern provided on the inner rotating cam 87a and the outer rotating cam 87b, it moves up and down while rotating.
- the uneven pattern provided on the rotating cam 87 is selected from different patterns according to the physical properties of the lubricant powder L.
- a flow control device 12 is connected to the input port 81 via a pipe T1, and the input boat 81 is generated by the air source 7 and specified by the flow control device 12. Compressed air adjusted to the flow rate is supplied.
- one end of a pipe T2 is connected to the output port 82.
- reference numeral 90 denotes a flow rate adjustment port provided as necessary.
- the flow rate adjustment port 90 has an output for adjusting the pressure of the air pulsation wave output from the output port 82.
- the regulating valve 9'1 is provided so as to be adjusted to a desired state from a state of complete communication with the atmosphere to a state of shutoff.
- the rotating cam 8 7 that can easily mix the lubricant powder L into the air is connected to the rotating shaft ma of the driving means (not shown) of the air pulsation wave generator 8. Attach to
- the rotating cam 87 is rotated at a predetermined rotation speed.
- the driving means (not shown) is controlled to rotate the rotating cam 87. Just change the speed.
- the air source 7, the flow control devices 12 and Z, or the output adjustment valve 91 may be adjusted as appropriate.
- the tablet-type tableting machine 2 When the tablet t is continuously tableted, first, the tablet-type tableting machine 2 is driven to rotate the rotary table 21 and a plurality of upper punches 23 and a plurality of lower punches. Rotate the pestle 24 at a specified speed.
- a plurality of upper punches 23 are sequentially fed into the upper punch receiving groove 31 of the powder material application device 3 for the upper punch.
- each of a plurality of statements 2 2 ′ and a plurality of statements 2 2 is sequentially fed.
- a positive pressure air pulsation wave is generated in the pipe T2.
- This “pulsating air pulsation wave” is a wave of air that pulsates at a constant frequency at a pressure higher than the atmospheric pressure outside the pipe T 2, An air wave that pulsates at a constant frequency at a pressure higher than the atmospheric pressure outside the pipe T2 and at a pressure whose vibration valley is approximately equal to the atmospheric pressure outside the pipe T2.
- the second suction means (not shown) is driven.
- the first suction means 11 When the first suction means 11 is driven, an airflow is generated uniformly from above to below from above the entire area of the slit portion 32 of the powder material applying device 3 for the upper punch.
- the air pulsation wave generator 8 when the air pulsation wave generator 8 is driven to generate positive and negative pressure air pulsation waves in the pipe T2, the air pulsation wave generator 8 generates the positive pressure air pulsation wave.
- the hole (slit) 54a of the elastic film 54 of the powder material discharge device (quantitative feeder) 5 repeatedly closes and closes and opens and closes.
- the lubricant powder L that has fallen into the dispersion chamber 55 becomes a swirling flow in the dispersion chamber 55. It mixes with pressure pulsating air, disperses and fluidizes.
- the powder for the upper punch is discharged from the discharge outlet 55b provided in the dispersion chamber 55 through the pipe T3 and the pipe T3a.
- the lubricant powder L sent to the powder inlet 33 of the material application device 3 and sent from the powder inlet 33 is discharged from the slit 32.
- a suction port T4a having a shape substantially similar to the shape of the slit portion 32 and having a size that covers the area of the slit portion 32 is provided. Since the first suction means 11 is driven, an airflow is generated uniformly above the entire area of the slit portion 32 and directed upward from below.
- the lubricant powder L moves from the entire area of the slit portion 32 uniformly from the lower side to the upper side in the suction port T4a direction.
- the upper punch 23 moves while moving from the starting end es of the slit portion 32 to the terminal end ee.
- the lubricant powder L coming from above to below from all over will continue to collide with the lower surface in a substantially vertical direction.
- the lubricant powder L is evenly applied to the lower surface S 23 of the upper punch 23, which is difficult to adhere due to gravity.
- the lubricant powder L mixed with and dispersed in the air pulsating wave air stream from the discharge port 55 provided in the dispersion chamber 55 is supplied to the lower punch through the pipe T3 and the pipe T3b.
- Lubricant jet Lubricant powder L sent to the powder material inlet e1 of the powder material application device 4 for the lower punch installed in the fog point P 1 b and sent from the powder material inlet e1 is After that, it passes through the through-hole h1 and is located below the powder material application device 4 for the lower punch from the outlet e2 of the through-hole h1. It is sprayed at a stretch onto the upper surface S24 of the lower punch 24 inserted to the position.
- the excess lubricant powder L adhered or deposited on the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the second punch 22 is supplied to the second suction means ( It is sucked through the suction port h5 (not shown). As a result, the powder material is uniformly applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 22.
- the molding material (granules) M is fed from the feedstock 25 into the space 22 into which the lower punch 24 has been inserted to a predetermined position.
- the scraper '26 is used for grinding, and the amount of the molding material (granules) M filled in the scraper 22 is adjusted to a predetermined amount.
- the scraper 26 is ground and filled with a predetermined amount of the molding material (granules) M.
- the scrap 22 is sent to the pre-compression point P 3 with the rotation of the rotary table 21, where After being pre-compressed by a pair of upper punches 23 and lower punches 24 by the preload rolls 27, 27, they are sent to the final compression point P4, where they are assembled by the main pressure rolls 28, 28.
- the upper punch 23 and the lower punch 24 are compressed by a predetermined tableting pressure into tablets t.
- the tablets t produced by compression molding at the compression point P 4 are sequentially sent to the tablet discharge point P 5, where the lower punch 24 moves upward in the die 22 at the tablet discharge point P 5. As a result, it is discharged out of the mortar 22 and is taken out to a predetermined place by the guide plate 29.
- the surface 22 of the upper punch 23, the upper punch 23 and the lower punch 24 are sequentially cleaned by suction means (not shown) or the like, and then sent to the lubricant spraying point P1 again. It is prepared for the next tableting process.
- the tablet T is continuously produced by continuously performing the above-described steps.
- the inner peripheral wall S2 2 of each of the plurality of dies 2 2 Lubricant powder L can be uniformly applied to each lower surface S 2 3 ⁇ and lower punch 2 4 ⁇ 's respective upper surface S 2 4 ⁇
- the lower surface of each of the upper punch 23 and the lower punch 24 The surface modifier can be uniformly applied to each of the inner peripheral wall surfaces S22 of the respective top surfaces S2 4. Therefore, the use of the external split type tableting machine 1 makes it possible to produce a tablet in which the surface modifier is uniformly applied to the surface of the tablet t.
- the width W32 of the slit portion 32 of the powder material application device 3 for the upper punch is made to substantially match the width of the area of the score line or the mark formed on the tablet,
- the lower surface S 2 3 of each of the upper punches 2 3 moving in the upper punch receiving groove 3 1 forms a parting line or a mark, that is, a complex convex portion is formed.
- the powder material is sufficiently and uniformly applied to the lower surface S 23 of each of the upper punches 23 around the part where the upper punch is located.
- a second suction means (not shown) is provided in the powder material application device 4 for the lower punch, and during the production of the tablet t, the second suction means is provided.
- the suction means (not shown) is driven, and the lower surface S of each of the lower punches 24.
- the space formed by the lower punch 24 and the die 22 is In the step of sequentially filling the molding material M, the powder material excessively adhering to the lower punch 24 and the die 22 and / or the excess powder material on the rotary table 21 are added to the molding material. It can be prevented from being mixed in.
- FIG. 13 is a plan view schematically showing another example of a powder material applying device for a lower punch according to the present invention.
- the powder material application device 4A for the lower punch is the same as the powder material application device 4 for the lower punch except for the following configuration. Are given the corresponding reference numerals, and their description is omitted.
- the powder material coating device 4A for the lower punch differs from the powder material coating device 4 for the lower punch in the following points.
- a slit-shaped molding material suction port h6 is provided at the front stage of the discharge port e2 on the surface S4a facing the rotary table 21.
- a third suction means (not shown) having a is further provided.
- the molding material suction port h 6 a of the third suction means (not shown) is provided with a plurality of lower punches 2.
- a third suction means (not shown) having a molding material suction port h6a is provided at the front stage of the discharge port e2 for discharging the lubricant powder L. ), And before spraying each of the lubricant powders L, the respective inner peripheral wall surfaces S22 and the lower punches 24 of the said 22. Since the top surface S24 is clean, the molding material M and lubricant powder used in the previous process do not mix into the tablets t Even if tablets are manufactured continuously, there is no unevenness in the amount of lubricant powder L used between tablets t As a result, tablets of the same standard can be manufactured continuously.
- the distance L (e2-h5) between the discharge port e2 and the suction port h5 is determined.
- at least the mortar 22 is longer than the diameter D22.
- the suction port of the second suction means (not shown) is moved at least from the position where the discharge port e2 is provided to the rotary table 21. Provided at a distance from the diameter D22 of each of the plurality of dies 22 (L (e2-h5)> D22).
- the powder material applying apparatus 4A for the lower punch also applies the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 (in this example, the lubricant powder L), extra powder material (in this example, lubricant powder L) is placed in the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 in a predetermined position in the die 22.
- the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 in this example, the lubricant powder L
- extra powder material in this example, lubricant powder L
- the condition is such that the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted into the die 22 to a predetermined position.
- the powder material in this example, lubricant powder L
- the powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the die 22 without giving the upper surface of the lower punch 24. Excess powder material (in this example, lubricant powder L) can be sucked and removed from the inner peripheral wall S22 of S24 and the mortar 22.
- the distance L (e2-h6 a) between the discharge port e2 and the suction port h6a is changed. At least, it is longer than the diameter D22 of 22.
- the suction port h6a of the third suction means (not shown) is moved at least from the position where the discharge port e2 is provided.
- the rotating table 21 is provided at a position apart from the diameter D22 of each of a plurality of said 22... (L (e2-h6)> D22).
- the powder material in this example, lubricant powder L
- the powder material is applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 22.
- unnecessary molding materials and powder materials in this example, lubricant powder L
- the place where the powder dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S24 of the lower punch 24 inserted to a predetermined position in 22 is a die 22
- the powder material dispersed in the air current of the air pulsating wave is placed on the upper surface S 24 of the lower punch 24 inserted to a predetermined position in Without affecting the conditions for directly spraying, the liquid adheres to the surface of the rotary table 21, the upper surface S24 of the lower punch 24, and the inner peripheral wall S22 of the die 22.
- FIG. 14 is a general configuration diagram schematically showing another example of the external lubricating tableting machine according to the present invention.
- -Fig. 15 shows the rotary table of the one-piece tableting machine that constitutes the external lubricating tableting machine shown in Fig. 14, the powder material application device for the upper punch and the powder material for the lower punch.
- FIG. 16 is a plan view schematically showing the arrangement of the coating apparatus of FIG. 15, and FIG. 16 is a schematic view in which the rotary table shown in FIG. 15 is cut and developed between a molding material filling point and a lubricant applying point. It shows a schematic development.
- This external lubricating tableting machine 1A is the same as the external lubricating tableting machine 1 shown in FIG. 1 except for the following points, and the corresponding components are denoted by the corresponding reference numerals. The description is omitted.
- This external lubricating tablet press 1A differs from the external lubricating tablet press 1 in the following points. You.
- the powder material application device 4 for the lower punch is not positioned in the reverse direction of the rotary table 21 but in the forward direction of the rotary table 21.
- a powder material coating device 3 for the upper punch is provided ("").
- the powder material applicator 3 for the upper punch is provided at the position opposite to the rotary table 21 in the forward direction with respect to the powder material applicator 4 for the lower punch. Since it may be provided, the external lubricating tablet press according to the present invention has a high degree of freedom in design.
- Embodiment 2 of the present invention relates to an example in which a powder material application device is used in which a powder material application device for an upper punch and a powder material application device for a lower punch are integrally provided. explain.
- FIG. 17 is an overall configuration diagram schematically showing an example of an external lubricating tableting machine equipped with such a powder material application device.
- the external lubricating tablet press shown in FIG. 17 is different from the external lubricating tablet press 1 shown in FIG. Since it is the same as that of the lubricating tablet press 1, the corresponding member devices are denoted by the corresponding reference numerals, and description thereof will be omitted.
- FIG. 18 is a plan view schematically showing an arrangement of a rotary table and a powder material coating device of the rotary tableting machine constituting the external lubricating tableting machine shown in FIG.
- FIG. 19 is a schematic developed view in which the rotary table shown in FIG. 17 is cut and developed between a molding material filling point and a lubricant application point.
- FIG. 20 is a plan view schematically showing the powder material coating device 13.
- FIG. 21 is a schematic sectional view taken along the line XXI—XXI in FIG. 20.
- FIG. 22 is a schematic sectional view taken along the line XXII—XXII in FIG. FIG.
- one of the two upper punches 23, 23 shown in FIG. 21 is represented by an imaginary line to facilitate understanding of the drawing. Is shown.
- the powder material coating device 13 is a powder material coating device 3B for the upper punch similar to the powder material coating device 3 for the upper punch 3 and a powder material coating device 4 for the lower punch 4
- a powder material application device 4 B for lower punches similar to that described above is configured as shown in FIG. More specifically, the powder material coating device 13 is fixedly provided at a predetermined position on the turntable 21.
- the material coating device 3B has a structure that is integrally connected.
- the powder material application device 13 includes a connection plate 13p.
- the connection plate 13 p is provided for facilitating the piping of the powder material to the applicator 13, and has a powder material inlet e 1, described later, on its upper surface.
- Connection ports e5 and e9 are provided.
- the surface S4a facing the rotary table is made a smooth surface so that the rotary table 21 can slide.
- the powder material application device 3B for the upper punch also has a smooth surface S3a facing the rotary table 21 so that the rotary table 21 can slide. .
- the powder material application device 4B for the lower punch has a powder material inlet e1 on its upper surface S4b for feeding the lubricant powder L dispersed in the air current of the air pulsation wave.
- the lubricant powder L sent to the powder material inlet e 1 passes through the through-hole hi provided so as to penetrate the powder material application device 4 B for the lower punch, and passes through the rotary table 21. It is sent to the surface S 4 a on the opposite side.
- the lubricant powder L discharged together with the positive pressure air pulsation wave from the outlet e 2 of the surface S 4 a facing the rotary table 21 of the through-hole hi is supplied to the lower punch.
- the inner peripheral wall S22 of the mortar 22 and the upper surface of the lower punch 24 inserted into the mortar 22 to a predetermined depth, which are accommodated below the powder material application device 4B for the mortar 22 It can be sprayed on 24.
- the powder material applying device 3B for the upper punch is formed so as to penetrate the powder material applying device 3 for the upper punch from the surface S3a on the side facing the rotary table 21 and A long slit section 32 curved along the rotation path of the upper punch and the outer surface S 3 b side of the powder applicator 3 B for the upper punch are provided on the side of the slit section 32.
- an upper punch accommodation groove 31 provided for accommodating a plurality of upper punches 23 rotating in a rotatable manner.
- the upper punch receiving groove 31 is provided so as to be curved along the rotation path Or of the plurality of upper punches 23.
- the width W 3 1 of the upper punch receiving groove 3 1 is equal to or slightly larger than the outer diameter of each of the plurality of upper punches 23.
- the lower surface S 23 of the upper punch 23 accommodated in the upper punch 23 is easily exposed to the lubricant powder L supplied from the slit portion 32, while being accommodated in the upper punch receiving groove 31.
- the lubricant powder L is hardly attached to the periphery of the upper punch 23.
- the configuration of the powder material coating device 3B for the upper punch and the powder material coating device 4B for the lower punch are as described above.
- the configuration of the powder material coating device 4 is the same as that of the powder material coating device 4.
- the powder material coating device 13 is a powder material coating device for the lower punch, which constitutes the powder material coating device 13.
- the lubricant powder L discharged in a state of being mixed with air from the surface S 4 a on the side of the through hole h 1 facing the rotary table 21 on the side of the rotary table 21 is further subjected to an upper punch. Is supplied to a slit portion 32 provided in a powder material coating device 3B.
- the surface S 4 a of the powder material application device 4 A for the lower punch facing the rotary table 21 is provided with a rotary table 21 1 In the direction opposite to the direction of rotation (see the direction of the arrow shown on the turntable 21 in Fig. 21), a long groove D curved along the rotation path Or of the plurality of dies 2 2 1 is formed.
- the width of the long groove D1 is the same as or slightly larger than the diameter of each of the plurality of said grooves 24.
- the long groove D 1 has a shape in which the discharge port e 2 of the through hole h 1 is slightly recessed from the surface S 4 a on the side facing the turn table 21 in a direction opposite to the rotation direction of the turn table 21. Have.
- the long groove D1 is connected to a long groove D2 provided below the slit portion 32 of the powder material applying device 3B for the upper punch.
- the long groove D 2 of the powder material applicator 3 for the upper punch has a surface S 3 on the side of the powder material applicator 3 for the upper punch facing the rotary table 21. It has a slightly concave shape from a.
- the long groove D 1 of the powder material application device 4 A for the lower punch is connected to the long groove D 2 of the powder material application device 3 B for the upper punch.
- Powder material applicator for punches 4 From the egress e2 of the through-hole hi of B, together with air, powder for lower punches ⁇ "
- the lubricant powder L sprayed on the upper surface S 24 of the lower punch 24 inserted to a predetermined position in the device 22 located below the material application device 4 B passes through the long groove D 1, It moves to the long groove D 2 and is discharged from the slit portion 32.
- the lower punch material coating device 4 B with the air is discharged from the outlet e 2 of the through hole hi of the lower punch powder material coating device 4 B.
- the lubricant powder L sprayed on the upper surface S 24 of the lower punch 24 inserted to a predetermined depth into the upper surface of the lower punch 24 is stored on the upper surface S 24 of the lower punch 24. Adhere to.
- the lubricant powder L which is excessively deposited on the upper surface S 24 of the lower punch 24, is sprayed on the inner peripheral wall surface S 22 of 22, and the inner peripheral wall surface S 22 of the mortar 22. Adhere to.
- the one-shot tablet press 2 When continuously compressing tablets t, first, the one-shot tablet press 2 is driven to rotate the rotary table 21 and a plurality of upper punches 23 and a plurality of lower punches. Rotate the pestle 24 at a specified speed.
- the powder material application device 3 for the upper punch which constitutes the powder material application device 13 is uniformly distributed over the entire area of the slit portion 3 2 of the B 3 B. An airflow is generated that goes upward from below.
- the air pulsation wave generator 8 When the air pulsation wave generator 8 is driven to generate a positive pressure air pulsation wave in the pipe T2, the air pulsation wave generator 8 responds to the positive pressure air pulsation wave. Then, the hole (slit) 54a of the elastic film 54 of the powder discharger (quantitative feeder) 5 opens and closes. When the hole (slit) 54 a of the elastic membrane 54 opens, the lubricant powder L that has fallen into the dispersion chamber 55 becomes a swirling flow in the dispersion chamber 55. It mixes with pressure pulsating air, disperses and fluidizes.
- a powder material coating device 13 is formed from a discharge outlet 55 b provided in the dispersion chamber 55 through a pipe T 3.
- the upper surface S 2 of the lower punch 24 inserted to a predetermined position in the lower punch 22 4, At a stretch, it is sprayed.
- the excess lubricant powder L deposited on the upper surface S 24 of the lower punch 24 and the inner peripheral wall surface S 22 of the lower punch 24 drives the first suction means 11.
- the space formed by the long grooves D 1 and the long grooves D 2 and the rotary table 21 is supplied to the slit section 32 by the airflow from the discharge port e 2 toward the slit section 32. .
- the suction port of the first suction means 11 from the slit section 32 is uniformly distributed in the area of the slit section 32. Since the airflow toward T4a is generated, the lubricant powder L mixed with the air discharged from the slit portion 32 moves on the airflow and moves in the direction of the suction port T4a.
- the upper punch 23 moves while moving from the starting end es of the slit portion 32 to the terminal end ee.
- the lubricant powder L coming from above to below from all over will continue to collide with the lower surface in a substantially vertical direction.
- the lubricant powder L is uniformly applied to the lower surface S23 of the upper punch 23, which hardly adheres due to gravity.
- the molding material (granules) M is fed from the feedstock 25 into the space 22 into which the lower punch 24 has been inserted to a predetermined position.
- the scraper 26 is used for grinding, and the amount of the molding material (granules) M filled in the mortar 22 is adjusted to a predetermined amount.
- the upper punch 23 and the lower punch 24 are compressed by a predetermined tableting pressure into tablets t.
- the tablets t produced by compression molding at the compression point P 4 are sequentially sent to the tablet discharge point P 5, where the lower punch 24 moves upwards in the tablet discharge point P 5.
- the water is discharged out of 22 and is taken out to a predetermined place by the guide plate 29.
- the surface 22 of the upper punch 23, the upper punch 23 and the lower punch 24 are sequentially cleaned by suction means (not shown) or the like, and then sent to the lubricant spraying point P1 again. It is prepared for the next tableting process.
- the tablet T is continuously produced by continuously performing the above-described steps.
- the inner peripheral wall surface S2 2 ⁇ of each of the plurality of dies 2 2 ⁇ ′ of the tableting machine 2 and the lower surface S of each of the upper punches 2 3 ⁇ 2 3 ⁇ ⁇ ⁇ and lower punch 2 4 ⁇ ⁇ ⁇ ' can evenly apply the lubricant powder L to the upper surface S 2 4 ⁇ ⁇ ⁇
- the lower surface S 23 of each of the upper punches 23 and the lower punches 24 The surface modifying agent can be uniformly applied to each of the inner peripheral wall surfaces S22 of each of the upper surfaces S2 4,. Therefore, by using this external splittable tableting machine 1B, it becomes possible to produce a tablet in which the surface modifier is uniformly applied to the surface of the tablet t.
- the width W32 of the slit portion 32 of the powder material application device 3B for the upper punch is made to substantially match the width of the area of the score line or the mark formed on the tablet.
- the upper punches 23, which move in the upper punch receiving groove 31, form a part forming a score line or an engraving of the lower surface S23 of each of the upper punches 23, that is, a complex convex portion is formed.
- the powder material can be sufficiently and uniformly applied to the lower surface S2 3... Of each of the upper punches 2 3.
- this external lubricating tableting machine 1B it is conventionally difficult to produce on an industrial basis, but it is possible to produce an external lubricating tablet with a score line or engraving on a production basis. become able to.
- the surface modifier powder is used as the powder material, the surface modifier is uniformly applied to the part where the score line or the marking is provided, which has been difficult to manufacture conventionally. Tablets can be manufactured.
- a second suction means (not shown) is provided in the powder material applying device 4 for the lower punch, and the second pressing means is used during the production of the tablet t.
- the suction means (not shown in the figure) is driven, and the lower surface S 24 of each of the lower punches 24 and the mortar 22 are driven by the slit portion h5. Excessive powder material adhering to the peripheral wall surface S22 and / or excess powder material on the turntable 21 are removed.
- the powder material extraly attached to the lower punch 24 and said 22 and / or the excess powder material on the turntable 21 are Mixing into the molding material can be prevented. This makes it possible to efficiently manufacture an external lubricating tablet that does not contain the lubricant powder L or a surface modifier therein.
- the lower punch material coating device 4 is placed in a position opposite to the rotation direction of the rotary table 21 (upstream side).
- the powder material coating device 3 is connected, and the lubricant powder L mixed with the air is discharged into the outlet e2, the long groove Dl, the long groove D2, the slit 32, and the rotation direction of the rotary table 21. Since the air flows in the opposite direction, the moving direction of the upper punch 23 moving in the upper punch receiving groove 31 is opposite to that of the airflow containing the lubricant powder L. Therefore, the lubricant powder L can be efficiently applied to the lower surface S 23 of the upper punch 23.
- the distance L (e 2 ⁇ h) between the discharge port e 2 and the suction port h 5. 5) is made longer than at least the diameter D22 of 22.
- the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. It is provided at a position distant from the diameter D22 of each of a plurality of statements 22 provided on the tape 21 (L (e2-h5)> D22).
- the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the die 22 (in this example, Lubricant powder L)
- the extra powder material (in this example, lubricant powder L) is added to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the mortar 22 in the mortar 22.
- FIG. 23 is a plan view C schematically showing another example of the powder material coating apparatus according to the present invention.
- the powder material coating device 13A is the same as the powder material coating device 13 shown in FIG. 20 except that the shape of the slit portion 32 is zigzag.
- the corresponding members are denoted by the corresponding reference numerals, and description thereof will be omitted.
- the slit portion 32 since the slit portion 32 has a zigzag shape, the slit portion 32 moves in the upper punch receiving groove 31.
- the shape of 2 is simply curved along the rotation trajectory Or of multiple upper punches 2 3
- the lubricant powder L is used as the powder material, a score line or a mark is formed on each of the tablets t, for example, on the lower surface S 23 of the upper punch 23. Even when the unevenness is provided, the tablet t can be manufactured without causing tableting troubles such as laminating, cabling, and stateing on the manufactured tablet t.
- the distance L (e 2 -h 5) between the discharge port e 2 and the suction port h 5 is defined as At least It is made longer than the diameter D22.
- the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. It is provided at a position further away from the diameter D 22 of each of a plurality of statements 22... Provided on the table 21 (L (e 2 — h 5)> D 22).
- the powder material coating device 4 B for the lower punch also uses the powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 22 (in this example, In the lubricant powder L), extra powder material (in this example, lubricant powder L) is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 22.
- the place where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted to a predetermined position in 22 (that is, the discharge port e 2) , Says that the air is removed by suction at a place where it does not conduct through 22, and the upper surface S 24 of the lower punch 24 inserted to a predetermined position in the
- the powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 24 without affecting the conditions for directly blowing the powder material dispersed in the airflow in this example,
- the lubricant powder L) (In this example, wax powder L) upper surface S 2 4 and ⁇ 2 2 of the inner circumferential wall surface S 2 extra powder material Te convex to second lower punch 2 4 can be Aspirate removed.
- FIG. 24 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
- the powder material coating apparatus 13 B shown in FIG. 20 is different from the powder material coating apparatus 1 shown in FIG. 20 except that a mesh means 14 having a predetermined hole diameter is further provided above the slit portion 32. Since this is the same as 3, the corresponding member devices are denoted by the corresponding reference numerals, and description thereof will be omitted.
- the mesh means 14 having a predetermined hole diameter is further provided above the slit portion 32, the powder material discharged from the slit portion 32 may be used.
- particles larger than the pore size of the mesh means 14 are collected by the mesh means 14.
- the powder material larger than the predetermined particle diameter from adhering to the lower surface S 23 ⁇ of each of the upper punches 23 ⁇ '.
- the lower surface S 2 3 ⁇ ⁇ ⁇ of each of the upper punches 2 3 The material can be applied evenly.
- the mesh means 14 is generated by driving the first suction means 11, so that the airflow moving upward from the slit part 32 is straightened.
- the powder material is uniformly applied to the lower surface S 23 of each of the upper punches 23 also by the rectifying action of the mesh means 14.
- the tablet t can be manufactured without causing tableting obstacles such as laminating, cabbing, and stateing on the manufactured tablet t.
- the distance L (e2 ⁇ h5) between the discharge port e2 and the suction port h5 is determined as follows. At least, it is designed to be longer than the 22 diameter D22.
- the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. It is provided at a distance from the diameter D22 of each of a plurality of statements 22 provided on the table 21 (L (e2-h5)> D22).
- the powder material coating device 4 B for the lower punch also uses the powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 22 (in this example, In the lubricant powder L), extra powder material (in this example, lubricant powder L) is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 22.
- FIG. 25 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention
- FIG. 26 is a schematic sectional view taken along line XXVI-XXVI in FIG. .
- FIG. 26 one of the two upper punches 23, 23 shown in FIG. 26 is shown by an imaginary line to facilitate understanding of the drawing.
- the powder material coating device 13C is provided with a slit-like shape at the front stage of the discharge port e2 on the surface S4a facing the rotary table 21.
- a powder material applicator 4C for lower punch is further provided with a third sucking I means (not shown) having a molding material suction port h6a.
- the portion indicated by h7 is a powder material (in this example, a lubricant powder) sprayed from the outlet e2 together with the positive pressure air pulsation wave for the upper punch.
- a conduit leading to the powder material application device 3B is shown, and h7a is an opening of the conduit h7.
- the molding material suction port h6a of the third suction means (not shown) is provided on the inner periphery of each of the upper surfaces S23,. It is provided to sequentially remove the molding material M adhering around the wall S 22 ⁇ and a plurality of said 22 ⁇ ⁇ '. It has a width that is approximately perpendicular to Or and that is approximately the same as or slightly larger than the diameter of each of the plurality of dies 22.
- the powder material mixed with air discharged from the outlet e2 of the powder material applying device 4C for the lower punch and the powder material applying device 3B for the upper punch 3 In order to prevent the suction from the molding material suction port h6a when sucking the third suction means (not shown) when feeding the powder to the lower punch, the powder for the lower punch is used instead of the long groove D1.
- the discharge port e2 and the slit section 32 are connected to each other by a through hole h7 provided in the material coating apparatus 4C so as not to conduct with the molding material suction port h6a.
- a third suction means (not shown) having a molding material suction port h6a is provided at a stage preceding the discharge port e2 for discharging the lubricant powder L.
- the inner peripheral wall S 22 ⁇ of each of the dies 22 ⁇ and the upper surface S 24 of the lower punch 24 ⁇ ⁇ ⁇ ⁇ Clean Since the molding material M and lubricant powder L used in the previous process do not mix into the tablets t produced in the next process, tablets t Also, there is no non-uniformity in the amount of the lubricant powder L used between the tablets. This enables continuous production of tablets t ⁇ ⁇ ⁇ of the same standard.
- the powder material application device 4C for the lower punch also requires the distance L (e2-h5) between the discharge port e2 and the suction port h5 to be at least 22 is made longer than the diameter D22.
- the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. It is provided at a position further away from the diameter D22 of each of a plurality of statements 22 provided on the table 21 (L (e2-h5)> D22).
- the powder material applying apparatus 4C for the lower punch the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 (in this example, the lubricant powder In L), extra powder material (in this example, lubricant powder L) is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 at a predetermined position in the lower 22.
- the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 in this example, the lubricant powder In L
- extra powder material in this example, lubricant powder L
- the powder material in this example, lubricant powder L
- the powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the die 22 without being removed, the upper surface of the lower punch 24
- Excess powder material in this example, lubricant powder L
- the distance L (e2-h6a) between the discharge port e2 and the suction port h6a is set to at least , Says that it is longer than 22 diameter D22.
- the suction port h6a of the third suction means (not shown) is moved at least from the position where the discharge port e2 is provided.
- the rotating table 21 is provided with a plurality of dies 22. (L (e 2—h6)> D 22).
- the powder material in this example, lubricant powder L
- the powder material is formed on the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 22.
- the lubricant powder L) can be removed by suction. Further, in the powder material application device 4C for the lower punch, the distance L (e2-h7a) between the outlet e2 and the opening h7a of the conduit h7 is determined by the diameter D22 of the die 22.
- the connection between the outlet e 2 and the opening h 7 a is made to be conductive via the line 22, and from the outlet e 2,
- extra powder material in this example, smooth
- the powder powder L) is guided through the conduit h7 into the slot D2.
- the opening h7a and the suction port h5 are also provided so that the powder sprayed with the positive pressure air pulsation wave from the outlet e2 is easily guided into the conduit h7 from the opening h7a.
- FIG. 27 is a plan view schematically showing another example of the powder material applying apparatus according to the present invention
- FIG. 28 is a schematic sectional view taken along line XXVIII-XXVIII in FIG. It is.
- one of the two upper punches 23, 23 shown in FIG. 28 is indicated by an imaginary line to facilitate understanding of the drawing.
- the powder material coating device 13D is the same as the powder material coating device 13 except for the following points. Description is omitted.
- the powder material coating device 13 D is applied to the powder material coating device 4 D for the lower punch, and the powder material coating device for the upper punch is positioned at a position in the direction of rotation of the rotary table 21. 4D has a connected structure.
- connection port e9 is connected to the suction port T4a, and the connection port e10 is connected to the powder material coating device 13D lower punch. It is connected to a recess 3c provided on the back surface (the surface on the side facing the rotary table 21) of the powder material application device 4D for use.
- the first suction means 11 is connected to the connection port e9, and when the first suction means 11 is driven, the first suction means 11 moves to the suction port T4a and goes into the suction port T4a. An airflow of a suction atmosphere is generated.
- connection port e10 When a suction means (not shown) is connected to the connection port e10 and the suction means (not shown) is driven, the suction atmosphere (not shown) is drawn into the recess 3c and into the recess 3c. The airflow is generated, and the molding material and the powder material (the lubricant powder L in this example) adhering to the turntable 21 can be removed.
- h8 is a powder material (in this example, a lubricant powder) sprayed from the outlet e2 together with the positive pressure air pulsation wave for the upper punch.
- a conduit leading to the powder material application device 3D is shown, and h8a represents an opening of the conduit h8.
- the powder material application device for the lower punch 4 D has a surface S 4 a on the side facing the rotary table 21, which has a discharge port in the forward direction (from the upstream side to the downstream side) in the rotation direction of the rotary table 21.
- a suction port h8a, and a suction port h5 of a second suction means are provided.
- the suction port h8a is used for supplying the powder material mixed with air discharged from the discharge port e2 to the slit portion 32 of the powder material application device 3D for the upper punch.
- the lower punch The powder material coating device 4D is provided through the through hole h8, which is provided so that the suction port h5 does not conduct. e2 and the slit are connected.
- the distance L (e2-h5) between the discharge port e2 and the suction port h5 is set to at least -22 It is made longer than the diameter D22.
- the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided.
- the plurality of dies 22 are provided on the table 21 at positions separated from the diameter D 22 of each of the dies 22 (L (e 2 ⁇ h 5)> D 22).
- the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 (in this example, the lubricant powder In L)
- extra powder material in this example, lubricant powder L
- the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 at a predetermined position in the lower 22.
- the distance L (e 2 -h8 a) between the outlet e 2 and the opening h 8 a of the conduit h8 is determined by the diameter of the mill 22. Compared to D22, the length is shorter (L ( ⁇ 2-h8a) D22), and the connection between the outlet e2 and the opening h8a is made to be conductive through 22 and the outlet e From Fig. 2, with the positive pressure air pulsation wave, in the sprayed powder material, for the inner peripheral wall S22 of 22 and the upper surface S24 of the lower punch 24, extra powder material (in this example) In this example, the lubricant powder L) is guided to the long groove D2 through the conduit h8.
- the opening h8a and the suction port h5 are also provided so that the powder material sprayed with the positive pressure air pulsating wave from the outlet e2 is easily guided into the conduit h8 from the opening h8a.
- the distance L (h8 a-h5) between them is at least longer than the diameter D22 of the mortar 22, so that the opening h8a and the suction port h5 do not conduct through the 22. (L (h8 a-h5)> D 22).
- FIG. 29 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
- FIG. 30 is a schematic sectional view taken along line XXX-XXX in FIG. It is.
- connection port e9 is connected to the suction port T4a, and the connection port e9 is connected to the first suction means 11.
- the first suction means 11 When the first suction means 11 is driven, an airflow of a suction atmosphere is generated at the suction port T4a toward the inside of the suction port T4a.
- FIG. 30 one of the two upper punches 23, 23 shown in FIG. 21 is shown by an imaginary line to facilitate understanding of the drawing.
- This powder material coating device 13E is an upstream side of the discharge port e2 of the powder material coating device 4D for the lower punch, which constitutes the powder material coating device 13D (the rotation direction of the rotary table 21). In the direction opposite to the above, a molding material suction port h6a connected to the third suction means (not shown) is further provided.
- the powder material coating device 13D is connected to the powder material coating device 4D for the lower punch and the powder material coating device 4 for the upper punch at a position in the forward direction in the rotation direction of the rotary table 21. D is connected.
- the surface S 4 a of the powder material application device 4 D for the lower punch facing the rotary table 21 is provided with a discharge port e 2, in the forward direction (from the upstream side to the downstream side) in the rotating direction of the rotary table 21.
- a suction port h8a and a suction port h5 for second suction means are provided.
- the suction port h8a is used to supply the powder material mixed with air discharged from the discharge port e2 to the slit 32 of the powder material application device 3D for the upper punch.
- sucking the suction means not shown
- the powder material mixed with the air discharged from the discharge port e2 is not sucked from the inlet port h5 so that the powder material for the lower punch is used.
- the suction port h5 is provided so as not to conduct, and the through hole h8 connects the discharge port e2 and the slit portion.
- a molding material is provided at the front of the discharge port e2 for discharging the lubricant powder L of the powder material coating apparatus 4E for the lower punch constituting the apparatus 13E.
- a third suction means (not shown) having a suction port h 6 a is provided, and before the lubricant powder L is sprayed on each of the dies 22, the inner circumference of each of the dies 22 is described.
- the distance L (e2-h5) between the discharge port e2 and the suction port h5 is set to at least the diameter D22 of the die 22. It is made longer than.
- the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. It is provided at a position distant from the diameter D22 of each of a plurality of sayings 22 ⁇ ⁇ 'provided on one bull 21 (L (e2-h5)> D22).
- the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 (in this example, the lubricant powder In L)
- extra powder material in this example, lubricant powder L
- the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 at a predetermined position in the lower 22.
- a place where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted up to is a place where it does not conduct through 22 Since suction removal is performed, the condition that the powder material dispersed in the air current of the air pulsating wave is directly sprayed on the upper surface S 24 of the lower punch 24 inserted to the predetermined position in the die 22 is affected.
- the upper surface S of the lower punch 24 in the powder material (in this example, the lubricant powder L) applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the die 22 Excess powder material (in this example, lubricant powder L) can be sucked and removed on the inner peripheral wall S22 of No. 24 and No. 22.
- the discharge port e2 and the conduit h8 are connected.
- the distance L (e2-h8a) between the opening h8a and the diameter D22 of the mortar 22 is made shorter (L (e2—h8a) less D22), and the outlet e2 and the opening h 8a through the mortar 22 so as to conduct, and from the discharge port e2 together with the air pulsation wave of positive pressure
- extra powder material in this example, lubricant powder L
- lubricant powder L is passed through the conduit for the inner peripheral wall S22 of the mortar 22 and the upper surface S24 of the lower punch 24. Through h8, it is guided to the long groove D2.
- the opening h8a and the suction port h5 are connected so that the powder material sprayed with the positive pressure air pulsation wave from the outlet e2 is easily guided into the conduit h8 from the opening h8a.
- the distance L (h8 a-h5) between them should be at least longer than the diameter D22 of 22 so that the opening h8a and the suction port h5 do not conduct through 22. (L (h8 a-h5)> D 22).
- the powder material application device 3 for the upper punch shown in the first embodiment of the invention is merely a preferable example for explaining the present invention, and there are various modifications.
- the slit portion 32 is formed in a zigzag shape, similarly to the powder material applicator 1.3A, or above the slit portion 32.
- the present invention includes a device provided with the mesh means 14 and a device provided with the slit means 32 in a zigzag shape and further provided with the mesh means 14 above the slit means 32 according to the present invention. It is included in the powder material application device for the upper punch.
- powder material coating apparatuses 13, 13A, 13B, 13C, and 13E shown in the second embodiment of the present invention merely describe preferred examples for describing the present invention, and There are variations.
- the slit portion 32 may have a zigzag shape similarly to the powder material coating device 13A, and a mesh means 14 may be provided above the slit portion 32 of the present invention. It is included in the powder applicator for upper punches according to the above. Further, as the external lubricating tableting machine according to the present invention, in Embodiment 1 of the present invention, both an applicator for the powder material for the upper punch and an applicator for the powder material for the lower punch are provided. However, the external lubricating tableting machine according to the present invention may include at least one of an applicator for a powder material for an upper punch and an applicator for a powder material for a lower punch. included. Next, the present invention will be described based on experimental examples.
- a powder material (magnesium stearate powder (in this example, powder of local government)) is stored in the hopper 51 using the powder material discharge device 5 shown in FIG. 7, and is stored in the dispersion chamber 55 in FIG.
- the supply air amount is 25 Newton liters / minute (N ⁇ 1 / min) (output value from the flow control device 21)
- the supply air pressure is 0.2Mpa
- the vibration frequency is An air pulsation wave of 20 hertz (Hz) was generated, and the change in the amount (spray amount) of the powder material discharged from the outlet 55b was measured temporarily.
- an air pulsation wave inlet 55 a was provided in the dispersion chamber 55 of the powder material discharge device 5 in a direction passing through the center line of the dispersion chamber 55, and the air pulsation wave was swirled in the dispersion chamber 55.
- the same experiment as in Experimental Example 1 was performed except that the amount was not changed, and the change in the amount of the powder material (spray amount) discharged from the discharge port 55b was temporarily measured.
- the new method shows the experimental results of Experimental Example 1 (when the powder material discharge device 5 according to the present invention is used), and the conventional method shows the experimental results of Comparative Example 1. Is shown.
- the spray amount indicates the weight (mg) of the powder material sprayed from the outlet 55b in one minute
- the CV indicates the ratio (%).
- R indicates the difference between the maximum value and the minimum value.
- the powder material discharged from 4a was uniformly dispersed in the swirling air pulsating wave.
- the powder material discharged from 54a was not uniformly dispersed in the air pulsation wave.
- the particle size of the powder material discharged from the outlet 55b is more uniform than the particle size of the powder material discharged from the outlet 55b in the conventional method. Was revealed.
- a powder material (magnesium stearate powder (pharmaceutical product in this example)) is stored in the hopper means 51 using the powder material discharging device 13 shown in FIG.
- the powder material extraction means (powder material extraction valve) 52 is controlled to open and close based on the detection values of the level sensor 56 and the powder material stored in the powder material storage chamber 53. While constantly controlling the height from the permeable membrane 54 to 10 mm ⁇ 2.5 mm, using the air pulsation wave generator 8 shown in Fig. 12, the supply air volume is 25 Newton-liter. / Min (N.1 / min) (output value from the flow controller 12), supply air pressure is 0.2 Mpa, and a frequency of 20 Hz (Hz) is generated and discharged. Changes in the amount (spray amount) of the powder material discharged from the mouth 55b were measured over time. (Experimental example 3)
- Experimental example 2 is the same as the experiment except that the height from the elastic block 54 was always controlled to 70 mm and the soil to 2.5 mm, and the powder discharged from the discharge port 74 b was used. Changes in the amount of spray (spray amount) were measured over time.
- the height of the powder material stored in the powder material storage chamber 2 from the elastic membrane 54 can be constantly discharged from the discharge port 55 b in order to discharge a constant amount of the powder material. It has been found that it is always preferable to keep the value approximately constant.
- Comparative Example 2 shows an example in which tablets were continuously tableted using the same device as the external lubricating tableting machine described in JP-A-56-14098.
- the magnesium stearate powder placed on the upper surface of the lower punch was blown off, and the upper surface of the lower punch, the lower surface of the upper punch, and the inside of the mill with the lower punch inserted to the specified position Magnesium stearate powder is applied to the peripheral wall, and the upper punch with magnesium stearate powder applied to the lower surface, the lower punch with magnesium stearate powder applied to the upper surface, and the inner peripheral wall as described above.
- Magnesium stearate Continuous tableting was attempted using a die coated with gum powder.
- the external lubricating tableting machine 1B provides continuous tableting without adding a lubricant to the molding material, even if the tablet has a complex uneven shape such as stamping. It became clear what we could do. '
- FIG. 33 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
- This powder material coating device 13F is a powder material coating device 13 shown in FIG. The same as the powder applicator 13 except that the powder material applicator 3F for the upper punch is used instead of the powder applicator 3B for the upper punch that constitutes It has a configuration. As shown in Fig. 33, instead of the slit of the powder material coating device 3B for the upper punch, the powder material coating device 13F is provided on the bottom surface of the upper punch receiving groove 31 as shown in Fig. 33.
- the air pulsation is generated on the lower surface S2 3 of each of the plurality of upper punches 2 3 moving along the rotation path of the upper punches 2 3
- a plurality of injection holes hs are arranged for spraying a powder material (in this example, lubricant powder L) dispersed in a wave current.
- a powder material in this example, lubricant powder L
- a plurality of upper punches 23 move along the rotation path of the upper punches 2 3 on the bottom surface of the upper punch receiving grooves 31.
- each of the injection holes hs provided in the center row and both sides of the injection holes hs are provided. If the injection holes hs... Provided in the rows are alternately provided, the same effect as when the slit portions 32 are provided in a zigzag manner can be obtained.
- the powder material mixed with the air pulsating wave is applied to the upper surface of the lower punch, where the powder material is easily attached and deposited.
- directly spraying by blowing off the powder that has accumulated extra, Excessive powder material is prevented from adhering and accumulating on the upper surface of the lower punch, and the powder material is uniformly applied to the upper surface of the lower punch.
- the powder material is less likely to adhere, and the inner peripheral wall where the lower punch has been inserted to a predetermined position has excess powder material blown off from the upper surface of the lower punch. Because the part adheres, the same amount of powder material as that applied to the upper surface of the lower punch is uniformly applied to the inner peripheral wall surface.
- the powder material not applied on the upper surface of the lower punch and the inner peripheral wall is mixed with air, dispersed, and sent to the lower surface of the upper punch constituting the next set in a fluidized state.
- the powder material On the lower surface of the upper punch, the powder material is put on the airflow from the lower side to the upper side with respect to the lower surface of the upper punch, so that the powder material adheres over time, so that the powder material is related to gravity.
- Approximately the same amount of powder material as that applied to the upper surface of the lower punch and the inner peripheral wall is said to be uniformly applied to the lower surface of the upper punch, which is difficult to adhere to.
- the powder material is applied to the inner peripheral wall surface where the upper surface of the lower punch and the lower punch are inserted to a predetermined position, and the powder is applied to the lower surface of the upper punch.
- the body material is applied by a series of airflows, and extra powder material is used to apply to the lower surface of the upper punch, on the upper surface of the lower punch and on the inner peripheral wall.
- the powder material can be used effectively without waste.
- the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface of the die among the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface of the die are described.
- the material is sucked and removed from the place where the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface of the lower punch inserted into the specified position inside the pier, where it does not conduct.
- the surface of the lower punch and the inner wall of the lower punch are not affected by the condition that the powder dispersed in the air pulsation wave is directly blown onto the upper surface of the lower punch inserted into the mortar to a predetermined position. Excess powder can be removed by suction from the applied powder material on the upper surface of the lower punch and the inner peripheral wall.
- the lower punch is located at the lowest position in The powder material is applied to the upper surface of the lower punch and the inner peripheral wall, and when the molding material is compression-molded, the powder material is uniformly applied to the inner peripheral wall that comes into contact with the molding material. Because it is applied, the molding material does not adhere when manufacturing tablets. As a result, tablets can be manufactured without causing tableting troubles such as stateing, laminating, and caving, thereby improving the tablet manufacturing efficiency.
- the inner peripheral wall surface where the lower punch is inserted to a predetermined position, the lower surface of the upper punch, and the powder material applying method according to claim 1 The powder material is applied to each of the upper surfaces of the lower punches, and the inner surface of the lower punch is uniformly coated with the powder material.
- the upper punch has a lower surface uniformly coated with the powder materials, and A tablet is manufactured by successively using lower punches having an upper surface on which a powder material is uniformly applied to compress the molding material.
- Kizuki says that without causing squealing and without tableting troubles (laminating, caving, sticking, etc.) Continuous tableting becomes possible. This makes it possible to manufacture external lubricating tablets on a production basis.
- the surface modifier when a surface modifier is used as the powder, the surface modifier can be uniformly applied by Kizuki.
- a tablet can be manufactured using a punch and a die to which the surface modifier has been uniformly applied, so that the surface modifier is uniformly applied to the surface of the tablet. Tablets can be manufactured.
- the powder material is applied to the inner peripheral wall surface where the upper surface of the lower punch and the lower punch are inserted to a predetermined position, and the powder material is applied to the lower surface of the upper punch. Is applied in a series of airflows, and excess powder material is used to coat the lower surface of the upper punch for the upper surface of the lower punch and the inner peripheral wall. It can be used effectively without waste.
- the tablet is applied to the upper surface of the lower punch and the inner peripheral wall surface.
- extra powder material for the upper surface of the lower punch and the inner peripheral wall of the die was dispersed in the air current of the air pulsating wave on the upper surface of the lower punch inserted to a predetermined position.
- the place where the powder material is directly sprayed is suction-removed in a place where it does not conduct, so it is dispersed into the air current of the air pulsating wave on the upper surface of the lower punch inserted up to the specified position.
- the powder material applied to the upper surface of the lower punch and the inner peripheral wall of the mortar without affecting the conditions for directly spraying the powdered material, excess powder for the upper surface of the lower punch and the inner peripheral wall The material can be aspirated off.
- the lower punch is applied with a powder material on the upper surface of the lower punch and the inner peripheral wall surface at the lowest position in the mold.
- the powder material is applied evenly to the inner peripheral wall that comes into contact with the molding material, so that the molding material does not adhere.
- a long slit portion for spraying the powder material dispersed in the air current of the air pulsating wave is provided on a lower surface of the upper punch, The powder material is sprayed on the lower surface of the upper punch over time while the upper punch passes over the slit part, so that the powder material is less likely to adhere due to gravity. Since the powder material is attached to the lower surface of the upper punch, the powder material can be evenly applied to the lower surface of the upper punch.
- the powder material application device for an upper punch wherein the rotary table is provided above the slit in a size large enough to cover the area of the slit, and when viewed in a plan view.
- a plurality of first suction means having suction ports shaped along the outer peripheral side of the rotating orbit are provided.
- the upper punch moves from the start to the end of the long slit on the lower surface of the upper punch provided for the next die, which moves inside the upper punch receiving groove.
- the powder material coming upwards from below is evenly colliding with the lower surface in a substantially vertical direction.
- the powder material that blows out from the lower part to the upper part from the entire area of the slit is evenly attached to the lower part of the upper punch. Can be applied.
- the powder material mixed with air is made to flow in the direction opposite to the rotation direction of the turntable, the powder material mixed with air is made to flow in the forward direction with the rotation direction of the turntable.
- the powder material can be made to efficiently collide with the lower surface of the upper punch as compared with the configuration described above.
- the powder material applying device for the upper punch the powder material can be efficiently and uniformly applied to the lower surface of the upper punch in this manner.
- the powder material applying device for the upper punch is used, the lower surface is uniformly coated with the powder material, and the upper surface is uniformly coated with the powder material. Tablets can be manufactured using the lower punch that has been applied and the fact that the powder material has been applied evenly on the inner peripheral wall, so if a lubricant is used as the powder material, According to Kizuki, it is possible to perform continuous tableting without causing squeaks and without tableting troubles (laminating, cabbing, sticking, etc.). This allows the production of external lubricating tablets at the production pace.
- the surface modifier when a surface modifier is used as a powder, the surface modifier can be uniformly applied to the surface of the punch by using a powder material application device for the upper punch. Since tablets can be manufactured using a punch with a coating agent uniformly applied, it is possible to manufacture tablets in which the surface modifier is uniformly applied to the surface of the tablet.
- the width of the slit portion is made to substantially match the width of the area of the score line or the mark formed on the tablet.
- the powder material moves on the lower surface of the upper punch, moving around the part forming the score line or marking, that is, the part where the complex protrusion is formed, on the lower surface of the upper punch moving in the groove.
- the powder material applying device for the upper punch can be sufficiently and uniformly applied to a portion of the lower surface of the upper punch where a score line or an engraving is formed.
- the part of the tablet provided with a score line or a mark that is, a part having a complex unevenness, is used for laminating, caving, and state. Tablets can be produced without kinging.
- the powder material applying device for the upper punch it is difficult to apply the powder material using the conventional powder material applying device.
- the powder material can be applied sufficiently and evenly to the part that forms the powder, and if a surface modifier is used as the powder material, it has conventionally been difficult to manufacture the powder material.
- the slit portion has a zigzag shape.
- the upper punch which moves in the upper punch receiving groove, moves in the upper punch receiving groove as compared to the slit whose slit portion is simply curved along the rotation path of the plurality of upper punches. Since the powder material has passed through the longer slit when moving, the powder material is more sufficiently and uniformly applied to the lower surface of the upper punch.
- the powder material applying device for the upper punch can be sufficiently and uniformly applied to a portion of the lower surface of the upper punch where a score line or a mark is formed. If a surface modifier is used as the powder material, tablets with the surface modifier applied uniformly at the part where the score line or marking is provided can be manufactured with even higher production efficiency. Will be able to
- a mesh means having a predetermined hole diameter is provided above the slit portion, and the powder material having a predetermined particle diameter or more is provided.
- the powder material applicator for the upper punch it is possible to easily produce a tablet on which the powder material is uniformly applied on the surface without making the tableting difficult. Further, since the air flow flowing from the slit portion to the suction port of the first suction means is rectified by the mesh means, the powder material is more uniformly applied to the lower surface of the upper punch.
- the inside of the upper punch receiving groove is formed along the rotation path of the plurality of upper punches on the bottom surface of the upper punch receiving groove.
- a plurality of injection holes for spraying powder material dispersed in the air current of the air pulsating wave are arranged on the lower surface of the plurality of upper punches that move. The powder material is sprayed from each of the plurality of injection holes. In this case, a certain rectifying effect is obtained in the airflow.
- the powder material dispersed in the air current of the air pulsating wave is discharged from an outlet to a lower punch inserted into a die to a predetermined position. Due to the air pulsation wave amplitude, due to the gravitational force due to the amplitude of the air pulsation wave, even if powder material accumulates extra on the upper surface of the lower punch, the air pulsation wave causes such extra powder As a result of the body material being blown off from the upper surface of the lower punch, the powder material can be uniformly applied to the upper surface of the lower punch, where excess powder material tends to accumulate due to gravity.
- the powder material blown off from the upper surface of the lower punch adheres to the inner peripheral wall surface, so that the powder material can be uniformly applied to the inner peripheral wall surface of the mill.
- the lower punch is inserted to a predetermined position from a discharge hole of a through hole provided so as to penetrate the main body.
- the powder material mixed with the air pulsation wave is directly blown.
- excess powder material which easily adheres or accumulates on the upper surface of the lower punch, is blown off from the upper surface of the lower punch by the air pulsating wave. It is applied evenly.
- a molding material filling portion is provided at a position downstream of the second suction means, in the step of filling the molding material into the space formed by the lower punch and the lower punch, the lower punch and the extra It is possible to prevent the adhering powder material and excess powder material on the rotary table from being mixed into the molding material.
- the suction port of the second suction means is arranged so as to be orthogonal to the plurality of rotation trajectories, and to each of the plurality of rotations and the periphery thereof.
- the second suction means is driven by the lower punch and the powder material adhering extra to the lower punch and the excess powder material on the rotary table. Can be removed more efficiently.
- the powder material applying apparatus for a lower punch In the powder material applying apparatus for a lower punch according to claim 21, the powder material applied to the upper surface of the lower punch and the inner peripheral wall of the die, The place where the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface of the lower punch inserted into a predetermined position in the above-mentioned area is sucked and removed. So that the powder material dispersed in the air current of the air pulsating wave is directly sprayed onto the upper surface of the lower punch inserted into the mortar to the specified position, without affecting the condition of the lower punch. Of the powder material applied to the upper surface and the inner peripheral wall surface of the die, the excess powder material for the upper surface of the lower punch and the inner peripheral wall surface can be removed by suction.
- the lubricant is discharged.
- a third suction means having a molding material suction port is provided in the front part of the mouth to clean the inner peripheral wall surface and the upper surface of the lower punch before spraying the lubricant. Since the molding materials and lubricants used do not mix into tablets in the next process, even if tablets are manufactured continuously, the amount of lubricant used among tablets may be uneven. Absent. As a result, tablets of the same standard can be manufactured continuously.
- the lower punch is inserted to a predetermined position from a discharge hole of a through hole provided in the powder material applying apparatus for the lower punch. Then, the powder material mixed with the air pulsation wave is directly blown. As a result, excess powder material, which easily adheres or accumulates on the upper surface of the lower punch, is blown off from the upper surface of the lower punch by the air pulsating wave. It is applied evenly.
- the powder material adhering extra to the inner peripheral wall is also blown off by the air pulsating wave, so the powder material is uniformly applied to the inner peripheral wall.
- the powder material applying device for the upper punch is connected to the powder material applying device for the lower punch in a direction opposite to the rotation direction of the rotary table, and the powder for the lower punch is connected.
- the powder material sprayed on the upper surface of the lower punch inserted into the upper punch to a predetermined depth is further supplied to a slit provided in a powder material application device for the upper punch.
- the excess powder material blown off from the upper surface of the lower punch and / or the inner peripheral wall surface by the air pulsation wave is mixed with the air, and in a direction opposite to the rotating direction of the rotary table (upstream side). And is released from the slit.
- the powder material coating device for the upper punch contains a plurality of upper punches that rotate and move so as to include a long slit region. Because the upper punch receiving groove is provided, the upper punch that moves in the upper punch receiving groove, on the lower surface of the upper punch While moving from the start to the end, the powder material coming from above and below from all over will continue to collide with the lower surface in a substantially vertical direction.
- the powder material is difficult to adhere due to gravity, So that the powder material is attached to the lower surface of the upper punch so that the powder material can be applied uniformly.
- the powder material mixed with air is made to flow in the direction opposite to the rotation direction of the turntable, the powder material mixed with air is made to flow in the forward direction with the rotation direction of the turntable.
- the powder material can be made to efficiently collide with the lower surface of the upper punch as compared with the configuration described above.
- the powder material application device can efficiently and uniformly apply the powder material to the lower surface of the upper punch.
- the lower punch on which the powder material is applied evenly on the lower surface
- the lower punch on which the powder material is applied evenly on the upper surface
- Tablets can be manufactured using the fact that the powder material is uniformly applied to the inner peripheral wall surface.
- Kizuki says, without causing squeaking and without tableting troubles (laminating, cabbing, sticking, etc.) Continuous tableting becomes possible. This makes it possible to manufacture external lubricating tablets on a production basis.
- the surface modifier can be uniformly applied to a punch and a die by using this powder material coating device.
- a tablet to which the surface modifier is uniformly applied can be manufactured with high production efficiency.
- the powder material application device for the upper punch constituting the powder material application device is provided above the slit portion of the powder material application device. Since the first suction means having the same configuration as that of the powder material applying device for punches is provided, the same effect as the powder material applying device for upper punches according to claim 12 is provided. .
- the width of the slit portion of the powder material applying apparatus for the upper punch, which constitutes the powder material applying apparatus is set according to claim 13. 10.
- the shape of the slit portion of the powder material application device for the upper punch, which constitutes the powder material application device, is set as described in claim 14. Since it is formed in a zigzag shape as in the powder material application device for punches, the same effect as the powder material application device for upper punches according to claim 14 can be obtained.
- the powder material applying device for the upper punch constituting the powder material applying device is provided above the slit portion of the powder material applying device. Since the mesh means having a predetermined hole diameter is provided similarly to the powder material application device for punches, the same effect as the powder material application device for upper punches according to claim 15 can be obtained.
- the powder material applying device according to claim 28, wherein the discharge port of the powder material applying device for the lower punch constituting the powder material applying device is the lower punch according to claim 18. In the same way as the outlet of the powder material applicator, it is located just below the outlet, and the lower punch is inserted to the specified position in the center of the lower punch.
- the powder material application device for lower punches according to claim 18 the same effect as the powder material application device for lower punches according to claim 18 can be obtained.
- the powder material application device for lower punches constituting the powder material application device is the powder material for lower punches according to claim 19. Since the second suction means having the same configuration as that of the material coating device is further provided, the same effect as the powder material coating device for lower punches according to claim 19 can be obtained.
- the suction port of the second suction means provided in the powder material applying apparatus for the lower punch constituting the powder material applying apparatus is provided. Since the configuration is the same as that of the apparatus for applying a powder material for a lower punch described in Item 0, the same effect as that of the apparatus for applying a powder material for a lower punch described in Item 20 is exhibited.
- the powder material applying device for the lower punch constituting the powder material applying device includes the powder for a lower punch according to claim 22.
- Material coating Since the third suction means similar to the cloth device is provided, the same effect as the powder material application device for lower punches according to claim 22 can be obtained.
- a plurality of the plurality of upper punches that move in the upper punch receiving groove along the rotation path of the plurality of the upper punches on the bottom surface of the upper punch receiving groove.
- a plurality of injection holes for spraying the powder material dispersed in the air current of the air pulsating wave are arranged, so when the powder material is sprayed from each of the plurality of injection holes, A certain rectifying effect is obtained in the airflow.
- the powder material coating apparatus for the lower punch which constitutes the powder material coating apparatus, is provided at a position in the forward direction with respect to the rotation direction of the rotary table. Since the powder coating device for the punch is connected, the rotation direction of the rotary table and the powder material coating device for the lower punch are supplied to the powder material coating device for the upper punch. Since the direction of the flow of the powder material mixed with the air is the same, the powder material can be applied to the lower surface of the upper punch with low resistance and in a quiet state.
- the external lubricating tableting machine for example, at a predetermined position (lubricant spraying point) of a conventional tableting machine such as a one-shot tableting machine, In a simple operation of fixedly attaching the powder material application device described in any of 3 above, if a lubricant is used as the powder material, no sticking occurs on the punch and die. In addition, continuous tableting becomes possible without causing tableting troubles (laminating, caving, sticking, etc.), thereby enabling production of external lubricating tablets on a production basis.
- a lubricating tablet press can be provided on the market.
- the surface modifier when a surface modifier is used as a powder, the surface modifier can be uniformly applied to a punch and a die.
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Abstract
Description
明 細 書 粉体材料の塗布方法、 錠剤の製造方法、 上杵用の粉体材料の塗布装置、 下杵用の粉体材料の塗布装置、 粉体材料の塗布装置、 及び外部滑沢式打 錠機 技術分野 Description Powder material coating method, tablet manufacturing method, powder material coating device for upper punch, powder material coating device for lower punch, powder material coating device, and external lubrication type Locking Machine Technical Field
本発明は、 粉体材料の塗布方法、 錠剤の製造方法、 粉体材料の塗布装置、 及び 外部滑沢式打錠機に関し、 特に、 空気脈動波に混和され、 打錠装置側に送られて くる滑沢剤等の粉体材料を、 上杵の下面、 下杵の上面及び曰の内周面に、 均一に 塗布することのできる、 粉体材料の塗布方法、 錠剤の製造方法、 粉体材料の塗布 装置、 及び、 そのような粉体材料の塗布装置を用いた外部滑沢式打錠機に関する。 背景技術 The present invention relates to a method for applying a powder material, a method for producing a tablet, an apparatus for applying a powder material, and an external lubricating tableting machine. In particular, the tablet is mixed with air pulsating waves and sent to the tableting device side. A powder material application method, a tablet manufacturing method, and a powder material capable of uniformly applying a powder material such as a lubricant to the lower surface of the upper punch, the upper surface of the lower punch, and the inner peripheral surface. The present invention relates to a material application device and an external lubricating tableting machine using such a powder material application device. Background art
成形材料を圧縮成形し錠剤を製造する際に、 打錠機の杵ゃ曰のギシツキや、 製 造される錠剤に、 スティヅキングゃラミネ一ティングゃキヤッビング等の打錠障 害を防ぐ技術としては、 例えば、 特閧昭 5 6— 1 4 0 9 8号公報に記載の外部滑 沢式打錠機や、 本発明者等が、 既に、 提案している外部滑沢式打錠機がある (特 開平 7— 1 2 4 2 3 1号公報を参照) 。 When compressing molding materials to produce tablets, the following techniques are used to prevent tableting failures such as sticking, laminating, and cabbing on tablets to be manufactured, such as punching of a tableting machine. For example, there is an external lubricating tableting machine described in Japanese Patent Application Publication No. 56-14098, and an external lubricating tableting machine that the present inventors have already proposed. Kaihei 7—See 1 2 4 2 3 1).
図 3 4は、 特開昭 5 6 - 1 4 0 9 8号公報に記載の従来の外部滑沢式打錠機を 用いて錠剤を製造する方法を概略的に示す工程図である。 FIG. 34 is a process chart schematically showing a method for producing tablets using a conventional external lubricating tableting machine described in Japanese Patent Application Laid-Open No. 56-14098.
この外部滑沢式打錠機 1 0 1では、 '錠剤は以下の方法により製造される。 In this external lubricating tablet press 101, tablets are produced by the following method.
まず、 図 3 4 ( a ) 及び図 3 4 ( b ) に示す工程において、 周方向に複数の曰 1 2 2 · · ·が設けられ且つ回転可能に設けられた回転テーブル 1 2 1上の所定 の位置に滑沢剤散布器 1 9 1を設け、 散布器 1 9 1内に、 回転テーブル 1 0 2の 回転により、 順次、 収容されてくる曰 1 2 2 · · ·の各々内に、 所定の位置まで 挿入された下杵 1 2.4の上面 S 1 2 4に、 滑沢剤粉末 Lを載せる。 First, in the steps shown in FIGS. 34 (a) and 34 (b), a predetermined number on a turntable 12 1 provided with a plurality of words 122 The lubricant sprayer 191 is provided at the position of, and in the sprayer 191, the rotation of the rotary table 102 sequentially turns into The lubricant powder L is placed on the upper surface S 1 24 of the lower punch 1 2.4 inserted up to the position of.
その後、 図 3 4 ( c ) に示す工程において、 散布器 1 9 1の後段側に設けられ た滑沢剤散布室 192内に、 回転テーブル 121の回転により、 順次、 収容され てくる、 上杵 123 · · ·、 上面 S 123 · · ·に滑沢剤粉末 Lが載置された下 杵 124 · · ·が所定に位置迄挿入された臼 122 · · ·に対し、 散布室 19.2 内に設けられたノズル 193から、 下杵 124 · · ·の各々の上面 S 124 · ·Then, in the process shown in Fig. 34 (c), the sprayer 19 The lower punch with lubricant powder L placed on the upper punch 123 ··· and the upper surface S 123 ··· successively accommodated in the lubricant spraying chamber 192 by the rotation of the rotary table 121. With the die 122 inserted into the specified position, the nozzle 193 provided in the spraying chamber 19.2 moves the upper surface of each of the lower punches 124 S 124
•に、 圧縮エアを噴射させることにより、 下杵 124 · · ·の各々の上面 S 12 4 · · ·に載置された滑沢剤 Lを、 上方に吹き飛ばして離散し、 この離散された 滑沢剤粉末 Lを、 臼 122 · · ·の各々の内周面 S 122 · · ·や、 上杵 123Then, by blowing compressed air, the lubricant L placed on the upper surface S124 of each of the lower punches 124 is blown upward to be separated and separated. The powder powder L is applied to the inner peripheral surface of each of the mortars 122
. · ·の各々の下面 S 123 · · ·に付着させ、 しかる後に、 内周壁面 S 122Attached to each lower surface S 123, and then the inner peripheral wall S 122
• · ·の各々に滑沢剤粉末 Lが塗布された臼 122 · · ·、 下面 S 123 · · · の各々に滑沢剤粉末 Lが塗布された上杵 123 · · ·、 及び、 上面 S 124 · ·• A die 122 with lubricant powder L applied to each of the lower surfaces S 123 • An upper punch 123 with lubricant powder L applied to each of the lower surfaces S 123 · · · and an upper surface S 124
•の各々に滑沢剤粉末 Lが塗布された下杵 124 · · ·の各々を用いて、 成形材 料 Mを、 圧縮成形し、 錠剤を製造するようにしている。 Using a lower punch 124 coated with lubricant powder L on each of the molding materials M, the molding material M is compression molded to produce tablets.
また、 図 35は、 特開平 7— 124231号公報に記載の、 本発明者等が既に 提案している、 従来の外部滑沢式打錠機の要部を概略的に示す構成図である。 この外部滑沢式打錠機 201は、 ロータリ型打錠機の回転テーブル 221の所 定の位置 (滑沢剤噴霧ポイント) に、 回転テーブル 221が摺動可能なように、 固定的に設けられた、 滑沢剤噴霧室 213を備える。 FIG. 35 is a configuration diagram schematically showing a main part of a conventional external lubricating tableting machine described in Japanese Patent Application Laid-Open No. 7-124231 and already proposed by the present inventors. The external lubricating tablet press 201 is fixedly provided at a predetermined position (lubricant spray point) of the rotary table 221 of the rotary tablet press so that the rotary table 221 can slide. In addition, a lubricant spray chamber 213 is provided.
滑沢剤噴霧室 21.3には、 空気脈動波発生装置 208が導管 T 202を介して 接続されている。 An air pulsation wave generator 208 is connected to the lubricant spray chamber 21.3 via a conduit T202.
導管 T 202の途中には、 滑沢剤粉末 Lを収容したホッパー 251が、 演算処 理装置 (図示せず。 ) により開閉制御可能な電磁弁で構成された滑沢剤切出弁 2 05を介在させて接続されている。 In the middle of the conduit T202, a hopper 251 containing the lubricant powder L is connected to a lubricant discharge valve 205, which is an electromagnetic valve that can be opened and closed by an arithmetic processing unit (not shown). It is connected with interposition.
尚、 図 35中、 T 203で示す部材は、 材料供給管を、 また、 259で示す部 材装置は、 ホッパー 251から滑沢剤粉末 Lの排出をスムーズにさせるために、 ホッパー 251内に圧縮空気を供給する空気源を、 各々、 示している。 In FIG. 35, the member indicated by T203 is a material supply pipe, and the member device indicated by 259 is compressed into the hopper 251 in order to smoothly discharge the lubricant powder L from the hopper 251. The air sources that supply the air are shown respectively.
また、 滑沢剤噴霧室 213内には、 回転テーブル 221の回転により、 回転テ —ブル 221に設けられた複数の日 222 · · ·が、 順次、 収容されるようにな つている。 Further, in the lubricant spray chamber 213, a plurality of days 222 provided on the rotary table 221 are sequentially stored by rotation of the rotary table 221.
且つ、 滑沢剤噴霧室 213内には、 複数の曰 222 · · ·の各々に対応して設 けられ、 且つ、 回転テーブル 221の回転により回転する複数の曰 222 · · · と同期して回転している、 複数の上杵 223 · · 'の各々、 及び、 複数の下杵 2 24 · · ·の各々が、 順次、 収容されるようになっている。 、. In addition, in the lubricant spray chamber 213, a plurality of Each of the plurality of upper punches 223 ··· 'and the plurality of lower punches 2 24 · · · rotating in synchronization with the plurality of statements 222 · · · rotated by the rotation of the rotary table 221. · Are to be accommodated in turn. ,.
また、 滑沢剤噴霧室 213には、 ブロア等の空気吸引手段 211が、 配管 T2 04を介して接続されている。 Further, an air suction means 211 such as a blower is connected to the lubricant spray chamber 213 via a pipe T204.
この外部滑沢式打錠機 201を用いて、 外部滑沢法により、 錠剤を連続打錠す る方法について説明する。 A method for continuously tableting tablets by the external lubrication method using the external lubricating tablet press 201 will be described.
錠剤を連続打錠する際には、 まず、 ロータリ型打錠機 202を駆動して、 回転 テーブル 221、 及び、 複数の上杵 223 · · ·、 及び、 複数の下杵 224 · · •を所定の回転速度で回転させる。 When tablets are continuously tableted, first, the rotary tabletting machine 202 is driven to rotate the rotary table 221 and a plurality of upper punches 223... And a plurality of lower punches 224. Rotate at the rotation speed of.
以上により、 滑沢剤噴霧室 213内に、 回転テーブル 221の回転により、 複 数の曰 222 · · ·の各々が、 また、 複数の曰 222 · · ·の各々に対応する、 複数の上杵 223 · · ·の各々、 複数の下杵 224 · · ·の各々が、 順次、 送り 込まれる。 As described above, in the lubricant spray chamber 213, the rotation of the rotary table 221 causes a plurality of upper punches corresponding to each of the plurality of 222 Each of the plurality of lower punches 224 is fed in order.
また、 空気脈動波発生装置 208を駆動して、 図 36 (a) 又は図 36 (b) に示すような、 正圧の空気脈動波を、 導管 T 202内に発生させる。 Also, the air pulsation wave generator 208 is driven to generate a positive pressure air pulsation wave in the conduit T202 as shown in FIG. 36 (a) or FIG. 36 (b).
ここに、 図 36 (a) に示す正圧の空気脈動波は、 その振動の山が、 導管 T2 02外の大気压より高い圧で、 且つ、 その振動の谷が、 導管 T 202外の大気圧 に概ね等しい圧で、 一定の周波数で脈動する空気の波を示しており、 また、 図 3 6 (b) に示す正圧の空気脈動波は、 その振動の山と谷とが、 ともに、 導管 T2 02外の大気圧より高い圧で、 一定の周波数で脈動する空気の波を示している。 次に、 空気吸引手段 211を駆動させる。 Here, the positive pressure air pulsation wave shown in FIG. 36 (a) has a peak of its vibration at a higher pressure than the atmosphere outside the conduit T202, and a trough of its vibration at its large peak outside the conduit T202. It shows a wave of air pulsating at a constant frequency at a pressure approximately equal to the atmospheric pressure, and the pulsating air pulsation at positive pressure shown in Fig. 36 (b) shows that the peaks and valleys of the vibration are both Shows a wave of air pulsating at a constant frequency above atmospheric pressure outside conduit T202. Next, the air suction means 211 is driven.
この装置 201では、 空気脈動波発生装置 208を駆動して、 導管 T 202内 に、 正圧の空気脈動波を発生させると、 正圧の空気脈動波に対応して、 滑沢剤切 出弁 205が、 連動して開閉するようになっている。 In this device 201, when the air pulsation wave generator 208 is driven to generate a positive pressure air pulsation wave in the conduit T 202, the lubricant discharge valve responds to the positive pressure air pulsation wave. 205 opens and closes in conjunction.
そして、 滑沢剤切出弁 205が開いた時に、 材料供給管 T 203内に落下した、 滑沢剤 Lは、 導管 213内送られ、 導管 T 202内で、 正圧の空気脈動波の気流 に分散し、 流動化されて、 導管 T 202の先端側に設けられたノズル手段 294 より、 滑沢剤噴霧室 213内に噴霧される。 この時、 滑沢剤噴霧室 2 1 3内に収容されている、 組となる、 下杵 2 2 4が所 定の位置まで挿入された状態の臼 2 2 2の内周壁面 S 2 2 2、 上杵 2 2 3の下面 S 2 2 3及び下杵 2 2 4の上面 S 2 2 4に滑沢剤粉末 Lが概ね同時に塗布される。 . 滑沢剤粉末 Lが塗布された、 曰 2 2 2、 上杵 2 2 3及び下杵 2 2 4は、 成形材 料充填ボイント (図 2及び図 3に示す成形材料充填ボイント P 2を参照。 ) に送 られ、 ここで、 日 2 2 2と下杵 2 2 4とにより形成されている空間内に、 成形材 料 (外部滑沢法では、 通常、 成形材料中に、 滑沢剤粉末 Lが添加 '混練されてい ない。 ) Mが充填される。 Then, when the lubricant discharge valve 205 is opened, the lubricant L that has dropped into the material supply pipe T 203 is sent into the conduit 213, and the airflow of the positive pressure air pulsating wave is And is fluidized and sprayed into the lubricant spray chamber 213 by nozzle means 294 provided at the end of the conduit T 202. At this time, the inner peripheral wall S 2 2 2 of the die 2 2 2, which is housed in the lubricant spraying chamber 2 13 and forms a pair, with the lower punches 2 2 4 inserted to a predetermined position. The lubricant powder L is applied almost simultaneously to the lower surface S2 23 of the upper punch 222 and the upper surface S224 of the lower punch 222. The lubricating powder L was applied, and the upper and lower punches 22, 23, and 22 were used as molding material filling points (see molding material filling points P 2 shown in FIGS. 2 and 3). ), Where the molding material (in the external lubrication method, usually contains the lubricant powder in the molding material) in the space formed by the day 222 and the lower punch 222. L added 'Not kneaded.) M is filled.
次いで、 成形材料 Mが充填された臼 2 2 2と下杵 2 2 4は、 すり切り手段 (図 示せず) により、 余分な成形材料が除去された後、 圧縮成形ポイント (図 2及び 図 3に示す予備圧縮ボイント P 3及び本圧縮ボイント P 4を参照。 ) に送れられ、 ここで、 組となる、 曰 2 2 2上杵 2 2 3及び下杵 2 2 4とにより圧縮成形されて、 錠剤にされる。 Then, after the mortar 222 and the lower punch 224 filled with the molding material M are removed by a cutting means (not shown), the excess molding material is removed, and then the compression molding point (see FIG. 2 and FIG. 3). The pre-compression point P 3 and the main compression point P 4 shown in the figure) are sent to, where they form a pair, and are compressed and formed by the upper and lower punches 22 and 22 and the tablets. To be.
その後、 このようにして製造された錠剤は、 順次、 錠剤排出ポイント (図 2及 び図 3に示す錠剤排出ポイント P 5を参照。 ) に送られ、 ここで、 口一タリ型打 錠から、 順次、 取り出されるようになつている。 Thereafter, the tablets manufactured in this manner are sequentially sent to the tablet discharge point (see the tablet discharge point P5 shown in FIGS. 2 and 3), where It is to be taken out sequentially.
この外部滑沢式打錠機 2 0 1は、 滑沢剤噴霧室 2 1 3内で、 正圧の空気脈動波 の気流に混和し、 分散させ、 流動化した滑沢剤粉末 Lを、 滑沢剤噴霧室 2 1 3内 に収容されている、 曰 2 2 2 · · ·、 上杵 2 2 3 · · '及び下杵 2 2 4 · · ·に 各々の組毎に同時に、 順番に塗布するようにし、 曰 2 2 2の内周壁面 S 2 2 2、 上杵 2 2 3の下面 S 2 2 3、 及び、 下杵 2 2 4の上面 S 2 2 4に、 滑沢剤粉未 L を均一に塗布し、 これにより、 外部滑沢法により錠剤を連続打錠しても、 打錠の 際に、 杵 2 2 3 · · ·、 2 2 4 · · · ·や、 臼 2 2 2 · · ·にギシヅキを生じる ことなく、 且つ、 製造される錠剤に、 打錠障害 (ラミネ一ティング、 キヤヅビン グ、 ステイツキング等) を生じることなく、 生産ペースで、 錠剤を製造すること ができるようになる。 This external lubricating tableting machine 201 mixes and disperses the fluidized lubricant powder L into the positive pressure air pulsating wave air stream in the lubricant spray chamber 2 13 to lubricate the lubricant powder L. It is housed in the spray agent spray chamber 2 1 3, said 2 2 2,, upper punch 2 2 3 'and lower punch 2 2 4 The inner peripheral wall S 2 2 2, the lower surface S 2 2 3 of the upper punch 2 2 3, and the upper surface S 2 2 4 of the lower punch 2 2 4 Even if the tablet is continuously compressed by the external lubrication method, even when the tablet is compressed, a punch 2 2 3 · · · 2 2 4 · · · It is possible to produce tablets at the production pace without causing squeaks and without causing tableting troubles (laminating, cabling, statesking, etc.) on the produced tablets. become.
ところで、 近時、 錠剤を、 その服用量を患者の体重や年齢に合わせた量で処方 できるようにして欲しい、 といったような医療現場のニーズに対応して、 分割可 能にするために、 錠剤の中央に割線を設けた分割可能錠剤や、 その製造元を容易 に特定できるようにするために、 会社コードを刻印した錠剤や、 その錠剤が何で あるかを容易に特定できるようにするため、 商品コードを刻印したりした錠剤を 市場に出荷したいという要望がある。 、. By the way, in recent years, in order to respond to the needs of the medical field, such as wanting to be able to prescribe the dosage according to the weight and age of the patient, tablets have been Tablet with a score line in the center of the tablet There is a request to ship tablets with a company code stamped on them so that they can be easily identified, or tablets with a product code stamped on them so that they can easily identify what the tablets are. . ,.
このような要望に応えるように、 錠剤の中央に割線を設けた分割可能錠剤や、 会社コードや商品コードを刻印した錠剤を、 外部滑沢式打錠機 1 0 1、 2 0 1を 用いて製造すると、 錠剤の割線を設けた部分や、 刻印を設けた部分に、 打錠障害 (ラミネ一ティング、 キヤッビング、 スティヅキング等) を生じ易くなる。 In order to meet such demands, dividable tablets with a score line at the center of the tablet and tablets with company code or product code stamped on them are externally lubricated tablet presses 101 and 201. When manufactured, tableting failure (laminating, cabbing, sticking, etc.) is likely to occur at the part where the tablet is scored or where the mark is provided.
また、 近時、 錠剤の表面の濡性を改善するために、 錠剤表面に表面改質剤を塗 布する場合があるが、 このような場合にも、 錠剤表面に、 割線や刻印等があると、 表面改質剤を均一に塗布できないという問題がある。 発明の開示 In recent years, a surface modifier may be applied to the tablet surface in order to improve the wettability of the tablet surface, but even in such a case, the tablet surface may have a score line or marking. Thus, there is a problem that the surface modifier cannot be applied uniformly. Disclosure of the invention
本発明は、 以上のような問題を解決するためになされたものであって、 外部滑 沢錠剤であって、 錠剤の中央に割線を設けた分割可能錠剤や、 会社コードや商品 コードを刻印した錠剤であっても、 打錠障害 (ラミネ一ティング、 キヤッビング、 スティヅキング等).を生じることなく連続打錠することのできる、 粉体材料 (滑 沢剤) の塗布方法、 錠剤の製造方法、 粉体材料の塗布装置、 及び、 外部滑沢式打 鍵機を提供することを目的としている。 The present invention has been made in order to solve the above problems, and is an external lubricating tablet, in which a dividable tablet provided with a dividing line in the center of the tablet, a company code or a product code is imprinted. Even tablets can be used for continuous tableting without causing tableting troubles (laminating, cabbing, sticking, etc.), powder material (lubricant) application method, tablet manufacturing method, powder The purpose is to provide a body material coating device and an external lubricated keying machine.
本発明は、 以上のような問題を解決するためになされたものであって、 外部滑 沢錠剤であって、 錠剤の中央に割線を設けた分割可能錠剤や、 会社コードや商品 コードを刻印した錠剤にも、 粉体材料 (表面改質剤) を均一に塗布することがで きる、 粉体材料 (表面改質剤) の塗布方法、 錠剤の製造方法、 粉体材料の塗布装 置、 及び、 外部滑沢式打錠機を提供することを目的としている。 The present invention has been made in order to solve the above problems, and is an external lubricating tablet, in which a dividable tablet provided with a dividing line in the center of the tablet, a company code or a product code is imprinted. Powder material (surface modifier) can be uniformly applied to tablets, powder material (surface modifier) coating method, tablet manufacturing method, powder material coating device, and The purpose is to provide an external lubricating tablet press.
本発明者等は、 外部滑沢錠剤であって、 錠剤の中央に割線を設けた分割可能錠 剤や、 会社コードや商品コードを刻印した錠剤を、 打錠障害 (ラミネ一ティング、 キヤッビング、 ステイツキング等) を生じることなく連続打錠することのできる 外部滑沢式打錠機の割沢剤の塗布装置等として好適な、 粉体材料の塗布装置の開 発に長年従事しており、 鋭意検討努力した結果、 一般に、 上杵の下面には、 滑沢 剤等の粉体材料が、 重力の関係により付着し難い一方、 下杵の上面には、 余分な 滑沢剤等の粉体材料が堆積し易い、 ということに気付くに至つた。 The inventor of the present invention has proposed tableting failure (laminating, cabbing, and state) for external lubricating tablets, which are dividable tablets having a score line at the center of the tablet or tablets with a company code or product code. Has been engaged in the development of powder material coating equipment suitable for use as a lubricant application equipment for external lubricating tablet presses that can continuously perform tableting without causing kinging. As a result of research, powder materials such as lubricants are generally difficult to adhere to the lower surface of the upper punch due to the gravity, while extra powder is attached to the upper surface of the lower punch. He came to realize that powder materials such as lubricants were easily deposited.
また、 上杵の下面、 臼の内周壁面及び下杵の上面に、 均一に、 滑沢剤等の粉体 材料を塗布するには、 組となる上杵、.臼及び下杵の表面に、词時に、 滑沢剤等の 粉体材料を塗布するよりは、 曰及び下杵の表面に比べ、 滑沢剤等の粉体材料が付 着し難い上杵の下面には、 臼及び下杵の表面への滑沢剤等の粉体材料の塗布工程 とは別に、 これらとは別条件で、 滑沢剤等の粉^"料を塗布する方が好ましいこ とを知見するに至った。 In order to uniformly apply a powder material such as a lubricant to the lower surface of the upper punch, the inner peripheral wall surface of the mortar, and the upper surface of the lower punch, the surfaces of the upper punch, At the time, rather than applying a powder material such as a lubricant, the lower surface of the upper punch, on which the powder material such as the lubricant is less likely to adhere than the surface of the lower punch, has a mortar and a lower part. In addition to the step of applying a powder material such as a lubricant to the surface of a punch, it has been found that it is preferable to apply a powder such as a lubricant under other conditions. .
そして、 余分な滑沢剤等が付着、 堆積し易い、 下杵の上面には、 一度に、 滑沢 剤等の粉体材料を強く吹き付け、 一方、 余分な粉体材料が付着、 堆積し易い、 下 杵の上面には、 上面に対して、 下方より上杵の下面方向に上昇する気流により、 粉体材料を、 時間を掛けて吹き付けるようにすれば、 曰の内周壁面、 下杵の上面 及び上杵の下面に均一に塗布できるのではないかと考え、 そのような、 滑沢剤等 の粉体材料を、 曰、 上杵及び下杵に吹き付ける方法や、 粉体材料塗布室の構造、 装置を研究した結果、 本発明を完成するに至った。 Excessive lubricant and the like easily adhere and accumulate. The upper surface of the lower punch is sprayed with a powder material such as a lubricant at once, while the extra powder material easily adheres and accumulates. On the upper surface of the lower punch, if the powder material is blown over the upper surface in a timely manner by an air current rising from the lower side to the lower surface of the upper punch, the inner peripheral wall, the lower punch We believe that it is possible to apply the powder uniformly to the upper surface and the lower surface of the upper punch, and to spray such a powder material such as a lubricant onto the upper and lower punches and the structure of the powder material application chamber. As a result of studying the device, the present invention was completed.
即ち、 請求項 1に記載の粉体材料の塗布方法は、 成形材料を圧縮成形する複数 の臼と、 複数の上杵及び複数の下杵の各々の表面に、 順次、 粉体材料を塗布する 粉体材料の塗布方法であって、 曰内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分散した粉体材料を直接吹き付けることで、 下杵の上面及び 曰の内周壁面に、 粉体材料を塗布する一方、 空気脈動波の気流に分散した粉体材 料を、 下杵と組をなさない上杵の下面に、 下方から上方に向かう気流下で、 塗布 するようにした。 That is, in the powder material applying method according to claim 1, the powder material is sequentially applied to a plurality of dies for compression-molding the molding material, and a surface of each of a plurality of upper punches and a plurality of lower punches. A method of applying a powder material, in which the powder material dispersed in the air current of the air pulsating wave is directly sprayed on the upper surface of the lower punch inserted to a predetermined position within the lower punch and the upper surface of the lower punch and the While applying the powder material to the inner peripheral wall, the powder material dispersed in the air current of the air pulsating wave is applied to the lower surface of the upper punch, which does not form a pair with the lower punch, under the air current that goes upward from below. I did it.
ここで、 本明細書で用いる用語、 「粉体材料」 は、 滑沢剤粉末又は表面改質剤 粉末を意味する。 Here, the term “powder material” used herein means a lubricant powder or a surface modifier powder.
滑沢剤としては、 粉末のものであれば、 種々のものを用いることができる。 そ のような滑沢剤としては、 例えば、 ステアリン酸金属塩 (M g塩、 C a塩等) や デンプン粉末や無水ケィ酸塩粉末等を挙げることができる。 As the lubricant, various powdery ones can be used. Examples of such a lubricant include metal stearates (Mg salt, Ca salt, etc.), starch powder, anhydrous silicate powder, and the like.
表面改質剤としては、 粉末のものであれば、 種々のものを用いることができる。 そのような表面改質剤としては、 例えば、 カルナパロウ、 ポリエチレングリコ一 ル、 シリカ等を挙げることができる。 この粉体材料の塗布方法では、 粉体材料が付着堆積し易い、 下杵の上面には、 空気脈動波に混和された粉体材料を直接吹き付けることで、 余分に堆積している 粉体材料を吹き飛ばすことにより、 下杵の上面に粉体材料が 分に付着堆積しな いようにし、 下杵の上面に、 粉体材料を均一に塗布するようにしている。 Various surface modifiers can be used as long as they are powdery. Examples of such a surface modifier include carnapa wax, polyethylene glycol, silica and the like. In this method of applying a powder material, the powder material is easily deposited and deposited. The powder material mixed with the air pulsating wave is directly sprayed on the upper surface of the lower punch, so that the excess powder material is deposited. By blowing off the powder, the powder material is prevented from adhering and accumulating on the upper surface of the lower punch, and the powder material is uniformly applied to the upper surface of the lower punch.
また、 下杵の上面に比べ、 粉体材料が付着し難い、 下杵が所定の位置まで挿入 された曰の内周壁面には、 下杵の上面から吹き飛ばされた余分な粉体材料の一部 が付着するので、 曰の内周壁面には、 下杵の上面に塗布したと概ね同じ量の粉体 材料が均一に塗布するようになる。 Also, compared to the upper surface of the lower punch, the powder material is less likely to adhere, and the inner peripheral wall where the lower punch has been inserted to a predetermined position has excess powder material blown off from the upper surface of the lower punch. Because the parts adhere, the same amount of powder material as the one applied to the upper surface of the lower punch is applied uniformly to the inner peripheral wall.
且つ、 下杵の上面及び曰の内周壁面において塗布されなかった粉体材料は、 次 の組を構成する上杵の下面に、 空気に混和し、 分散され、 流動化した状態で送ら れるが、 上杵の下面へは、 上杵の下面に対し、 下方から上方に向かう気流に、 粉 体材料を乗せて、 時間をかけて付着するようにしているので、 重力との関係で粉 体材料が付着し難い、 上杵の下面にも、 下杵の上面や曰の内周壁面に塗布したと 概ね同じ量の粉体材料が均一に塗布するようになる。 The powder material not applied on the upper surface of the lower punch and the inner peripheral wall is mixed with air, dispersed, and sent to the lower surface of the upper punch constituting the next set in a fluidized state. On the lower surface of the upper punch, the powder material is put on the airflow from the lower side to the upper side with respect to the lower surface of the upper punch, so that the powder material adheres over time, so that the powder material is related to gravity. Approximately the same amount of powder material as that applied to the upper surface of the lower punch and the inner peripheral wall is said to be uniformly applied to the lower surface of the upper punch, which is difficult to adhere to.
尚、 下杵の上面に、 余分な粉体材料が付着又は堆積しないように均一に塗布す るには、 下杵の上面の概ね中心部に、 概ね垂直方向に、 正圧の空気脈動波に混和 し、 分散させ、 流動化した粉体材料を吹き付けるのが好ましい。 In order to apply the powder material uniformly on the upper surface of the lower punch so as not to adhere or accumulate, it is necessary to apply a positive pressure air pulsation wave to the center of the upper surface of the lower punch in a substantially vertical direction. It is preferable to spray a powder material which has been mixed, dispersed and fluidized.
このようにすれば、 下杵の上面に杀分に付着堆積しがちな粉体材料は、 下杵の 上面の概ね中心部から、 下杵が所定の位置まで挿入された曰の内周壁面に万遍な く吹き付けられ、 これにより、 曰の内周壁面に、 粉体材料が均一に付着する。 請求項 2に記載の粉体材料の塗布方法は、 成形材料を圧縮成形する複数の曰と、 複数の上杵及び複数の下杵の各々の表面に、 順次、 粉体材料を塗布する粉体材料 の塗布方法であって、 粉体材料は、 下杵の上面及び曰の内周壁面、 次いで下杵と 組をなさない上杵に連続的に供給されるようになっており、 臼内に所定の位置ま で挿入された前記下杵の上面に、 空気脈動波の気流に分散した粉体材料を直接吹 き付けることで、 下杵の上面及び曰の内周壁面に、 粉体材料を塗布し、 次いで、 下杵と組をなさない上杵の下面に、 下方から上方に向かう気流下で、 塗布するよ うにした。 In this way, the powder material, which tends to adhere and accumulate on the upper surface of the lower punch, tends to adhere to the inner peripheral wall where the lower punch is inserted to a predetermined position from the approximate center of the upper surface of the lower punch. The powder material is evenly sprayed, whereby the powder material adheres uniformly to the inner peripheral wall. The method for applying a powder material according to claim 2 is a method for compressing and molding a molding material, wherein the powder material is sequentially applied to the surface of each of a plurality of upper punches and a plurality of lower punches. In the method of applying the material, the powder material is continuously supplied to the upper surface of the lower punch and the inner peripheral wall surface, and then to the upper punch which is not paired with the lower punch. The powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface of the lower punch inserted to a predetermined position, so that the powder material is applied to the upper surface of the lower punch and the inner peripheral wall surface. It was then applied to the lower surface of the upper punch, which did not form a pair with the lower punch, under an airflow from below to above.
この粉体材料の塗布方法では、 下杵の上面及び下杵が所定の位置まで揷入され た曰の内周壁面への粉体材料の塗布と、 上杵の下面への粉体材料の塗布とを一連 の気流の流れで行うようにし、 下杵の上面及び曰の内周壁面にとって、 余分な粉 体材料を、 上杵の下面への塗布に用いているので、 粉体材料を無駄なく、 有効活 用できる。 In this powder material application method, the upper surface of the lower punch and the lower punch are inserted to predetermined positions. The application of the powder material to the inner peripheral wall surface and the application of the powder material to the lower surface of the upper punch are performed by a series of airflows, and the upper surface of the lower punch and the inner peripheral wall are Since the excess powder material is used for application to the lower surface of the upper punch, the powder material can be effectively used without waste.
請求項 3に記載の粉体材料の塗布方法は、 請求項 1又は請求項 2に記載の粉体 材料の塗布方法の、 下杵と組をなさない上杵の下面に、 下方から上方に向かう気 流を、 上杵の下面より上方の位置に吸引口を有する吸引手段を駆動することによ り発生させると共に、 余分な粉体材料を吸引手段で吸引除去するようにした。 この粉体材料の塗布方法では、 上杵の下面より上方の位置に吸引口を有する吸 引手段を設けるという簡単な構成で、 上杵の下面に、 下方から上方に向かう気流 を発生させることができる。 The method for applying a powder material according to claim 3 is the method for applying a powder material according to claim 1 or 2, wherein the lower surface of the upper punch, which does not form a pair with the lower punch, faces upward from below. The airflow is generated by driving a suction means having a suction port at a position above the lower surface of the upper punch, and the excess powder material is suctioned and removed by the suction means. In this method of applying a powder material, a simple configuration in which suction means having a suction port is provided at a position above the lower surface of the upper punch can generate an airflow from below to above on the lower surface of the upper punch. it can.
また、 上杵にとつて、 余分な粉体材料 (例えば、 上杵の上面迄到達せず、 雲の ように漂うような粉体材料) は、 直ちに、 吸引口から、 吸引除去されるので、 粉 体材料が、 飛散して、 他の装置部分に付着することがない。 Also, for the upper punch, excess powder material (for example, powder material that does not reach the upper surface of the upper punch and drifts like a cloud) is immediately removed from the suction port by suction. The powder material does not scatter and adhere to other equipment parts.
請求項 4に粉体材料の塗布方法は、 請求項 1〜 3のいずれかに記載の粉体材料 の塗布方法の、 下杵の上面及び曰の内周壁面に塗布された粉体材料の中、 下杵の 上面及び日の内周壁面にとって余分な粉体材料を、 臼内に所定の位置まで挿入さ れた下杵の上面に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける場所 とは、 導通しない場所で、 吸引除去するようにした。 The method for applying a powder material according to claim 4 is the same as the method for applying a powder material according to any one of claims 1 to 3, except that the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface is used. Excessive powder material for the upper surface of the lower punch and the inner peripheral wall of the sun is sprayed directly onto the upper surface of the lower punch inserted into the mortar to the specified position, dispersed in the air current of the air pulsating wave The place is a place where it does not conduct, and it was made to remove by suction.
この粉体材料の塗布方法では、 下杵の上面及び曰の内周壁面に塗布された粉体 材料の中、 下杵の上面及び曰の内周壁面にとって余分な粉体材料を、 曰内に所定 の位置まで挿入された下杵の上面に、 空気脈動波の気流に分散した粉体材料を直 接吹き付ける場所とは、 導通しない場所で、 吸引除去するようにしているので、 臼内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分散した粉 体材料を直接吹き付ける条件に影響を与えることなく、 下杵の上面及び曰の内周 壁面に塗布された粉体材料の中、 下杵の上面及び臼の内周壁面にとって余分な粉 体材料を、 吸引除去することができる。 In this method of applying powder material, extra powder material for the upper surface of the lower punch and the inner peripheral wall among the powder materials applied to the upper surface of the lower punch and the inner peripheral wall is referred to as The place where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface of the lower punch inserted to the specified position is a place where it does not conduct electricity. The powder applied to the upper surface of the lower punch and the inner wall of the lower punch without affecting the conditions for directly blowing the powder material dispersed in the air current of the air pulsating wave onto the upper surface of the lower punch inserted up to the position Excess powder material in the upper surface of the lower punch and the inner peripheral wall of the die can be removed by suction.
尚、 下杵の上面及び曰の内周壁面に塗布された粉体材料の中、 下杵の上面及び Hの内周壁面にとって余分な粉体材料には、 回転テ一ブルの表面に付着している 粉 料も含まれる。 The powder material applied to the upper surface of the lower punch and the inner peripheral wall of the lower punch, and the extra powder material for the upper peripheral surface of the lower punch and the inner peripheral wall of the H, may adhere to the surface of the rotating table. ing Powder is also included.
請求項 5に記載の錠剤の製造方法は、 請求項 1〜 4のいずれかに記載の粉体材 料の塗布方法の、 所定の位置が、 下杵が曰内で最下位となる位置である。 In the method for producing a tablet according to the fifth aspect, the predetermined position in the method for applying a powder material according to any one of the first to fourth aspects is a position where the lower punch is located at the lowest position. .
この錠剤の製造方法では、 下杵が、 曰内で最下位となる位置で、 下杵の上面及 び臼の内周壁面に、.粉 料を塗布するようにし、 成形材料を圧縮成形する際に、 成形材料に接触する臼の内周壁面に、 万遍なく、 粉体材料を塗布するようにして いるので、 錠剤を製造する際に、 曰に成形材料が付着しない。 In this tablet manufacturing method, the lower punch is applied to the upper surface of the lower punch and the inner peripheral wall of the die at the lowest position in In addition, since the powder material is applied evenly to the inner peripheral wall of the die that comes into contact with the molding material, the molding material does not adhere when manufacturing tablets.
これにより、 ステイツキングや、 ラミネーティングや、 キヤッビング等の打錠 障害を生じることなく、 錠剤を製造できるので、 錠剤の製造効率が向上する。 請求項 6に記載の錠剤の製造方法は、 複数の曰と、 複数の曰の各々に対応する ように設けられた複数の上杵及び複数の下杵とを備え、 複数の臼、 複数の上杵及 び複数の下杵に、 順次、 粉体材料を塗布する工程と、 組となる、 粉体材料が塗布 された曰、 粉体材料が塗布された上杵及び粉体材料が塗布された下杵を用いて、 順次、 成形材料を圧縮成形する工程とを備え、 複数の曰と、 複数の上杵及び複数 の下杵に、 順次、 粉体材料を塗布する工程を、 曰内に所定の位置まで挿入された 下杵の上面に、 空気脈動波の気流に分散した粉# ^料を直接吹き付けることで、 下杵の上面及び曰の内周壁面に、 粉体材料を塗布する一方、 空気脈動波の気流に 分散した粉 料を、 下杵と組をなさない上杵の下面に、 下方から上方に向かう 気流下で、 塗布するようにした。 As a result, tablets can be produced without causing tableting troubles such as stateing, laminating, and cabbing, so that tablet production efficiency is improved. The tablet manufacturing method according to claim 6, comprising a plurality of statements, a plurality of upper punches and a plurality of lower punches provided so as to correspond to each of the plurality of statements, A step of sequentially applying the powder material to the punch and a plurality of lower punches, and a pair of the powder material was applied. The upper punch and the powder material coated with the powder material were applied. A step of sequentially compressing and molding the molding material using a lower punch; a plurality of said steps of sequentially applying a powder material to a plurality of upper punches and a plurality of lower punches are prescribed in the statement; The powder material dispersed in the air current of the air pulsating wave is directly sprayed on the upper surface of the lower punch inserted up to the position of, so that the powder material is applied to the upper surface of the lower punch and the inner peripheral wall, The powder dispersed in the air pulsating air current is applied to the lower surface of the upper punch that is not paired with the lower punch. , It was to be applied.
この錠剤の製造方法では、 請求項 1に記載の粉体材料の塗布方法を用いて、 下 杵が所定の位置まで挿入された曰の内周壁面、 上杵の下面、 及び、 下杵の上面の 各々に、 粉 料を塗布するようにし、 粉体材料が均一に塗布された内周壁面を 有する曰、 粉体材料が均一に塗布された下面を有する上杵、 及び、 粉体材料が均 一に塗布された上面を有する下杵を、 順次、 使用して、 成形材料を圧縮成形して、 錠剤を製造するようにしている。 - これにより、 粉体材料として、 滑沢剤を用いた場合には、 杵ゃ臼に、 ギシツキ を生じることなく、 且つ、 打錠障害 (ラミネ一ティング、 キヤヅビング、 スティ ッキング等) を生じることなく、 連続打錠が可能になる。 これにより、 生産べ一 スで、 外部滑沢錠剤の製造が可能になる。 また、 粉 料として、 表面改質剤を用いた場合には、 杵ゃ臼に、 表面改質剤 を均一に塗布できる。 In this tablet manufacturing method, the inner peripheral wall surface, the lower surface of the upper punch, and the upper surface of the lower punch where the lower punch is inserted to a predetermined position by using the powder material applying method according to claim 1 are described. The powder is applied to each of the two, and the inner peripheral wall surface on which the powder material is uniformly applied is described. The upper punch having the lower surface on which the powder material is applied uniformly, and the powder material is evenly applied. A lower punch having an upper surface applied at a time is sequentially used to compress the molding material to produce tablets. -As a result, when a lubricant is used as the powder material, the punch and the die do not suffer from stickiness and do not suffer from tableting troubles (laminating, caving, sticking, etc.). However, continuous tableting becomes possible. This makes it possible to manufacture external lubricating tablets on a production basis. When a surface modifier is used as the powder, the surface modifier can be uniformly applied to the punch and die.
これにより、 この錠剤の製造方法を用いれば、 表面改質剤 均一に塗布された 杵と曰とを用いて、 錠剤を製造できるので、 錠剤の表面に表面改質剤が均一に塗 布された錠剤を製造できるようになる。 By using this method of manufacturing tablets, tablets can be manufactured using a punch uniformly coated with a surface modifying agent, so that the surface modifying agent was uniformly applied to the surface of the tablets. Tablets can be manufactured.
請求項 7に記載の錠剤の製造方法は、 複数の曰と、 複数の曰の各々に対応する ように設けられた複数の上杵及び複数の下杵とを備え、 複数の曰、 複数の上杵及 び複数の下杵に、 順次、 粉体材料を塗布する工程と、 組となる、 粉 料が塗布 された曰、 粉体材料が塗布された上杵及び粉体材料が塗布された下杵を用いて、 順次、 成形材料を圧縮成形する工程とを備え、 複数の臼と、 複数の上杵及び複数 の下杵に、 順次、 粉体材料を塗布する工程は、 粉体材料は、 下杵の上面及び日の 内周壁面、 次いで前記下杵と組をなさない上杵に連続的に供給されるようになつ ており、 臼内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分 散した粉体材料を直接吹き付けることで、 下杵の上面及び曰の内周壁面に、 粉体 材料を塗布する一方、 空気脈動波の気流に分散した粉 料を、 下杵と組をなさ ない上杵の下面に、 下方から上方に向かう気流下で、 塗布するようにした。 この錠剤の製造方法では、 下杵の上面及び下杵が所定の位置まで挿入された曰 の内周壁面への粉体材料の塗布と、 上杵の下面への粉体材料の塗布とを一連の気 流の流れで行うようにし、 下杵の上面及び曰の内周壁面にとって、 余分な粉体材 料を、 上杵の下面への塗布に用いているので、 粉体材料を無駄なく、 有効活用で きる。 - 請求項 8に記載の錠剤の製造方法は、 請求項 6又は請求項 7に記載の錠剤の製 造方法の、 下杵と組をなさない上杵の下面に、 下方から上方に向かう気流を、 上 杵の下面より上方の位置に吸引口を有する吸引手段を駆動することにより発生さ せると共に、 余分な粉体材料を前記吸引手段で吸引除去するようにした。 The tablet manufacturing method according to claim 7, comprising a plurality of statements, a plurality of upper punches and a plurality of lower punches provided corresponding to each of the plurality of statements, A step of sequentially applying the powder material to the punch and a plurality of lower punches, and a step of applying the powder, which is a pair of the upper punch to which the powder material is applied and the lower part to which the powder material is applied; A step of sequentially compressing the molding material by using a punch, and a step of sequentially applying the powder material to a plurality of dies, a plurality of upper punches and a plurality of lower punches, wherein the powder material is The lower punch is continuously supplied to the upper surface of the lower punch and the inner peripheral wall of the sun, and then to the upper punch which is not paired with the lower punch. By directly blowing the powder material dispersed in the air current of the air pulsating wave, the powder material is applied to the upper surface of the lower punch and the inner peripheral wall surface. While applying a powder charge dispersed in a stream of pulsating vibration air, the lower surface of the punch on does not make lower punch and assembled, under a stream of air directed from below upward, and as applied. In this tablet manufacturing method, the application of the powder material to the inner peripheral wall where the upper surface of the lower punch and the lower punch are inserted to a predetermined position and the application of the powder material to the lower surface of the upper punch are described in a series. As the excess powder material is used for applying to the lower surface of the upper punch and the inner peripheral wall surface of the lower punch, the excess powder material is used for application to the lower surface of the upper punch. It can be used effectively. -The tablet manufacturing method according to claim 8 is characterized in that, in the tablet manufacturing method according to claim 6 or claim 7, the airflow from the bottom to the top is formed on the lower surface of the upper punch which is not paired with the lower punch. This is generated by driving a suction means having a suction port at a position above the lower surface of the upper punch, and excess powder material is suctioned and removed by the suction means.
この錠剤の製造方法では、 上杵の下面より上方の位置に吸引口を有する吸引手 段を設けるという簡単な構成で、 上杵の下面に、 下方から上方に向かう気流を発 生させることができる。 In this tablet manufacturing method, an airflow from below to above can be generated on the lower surface of the upper punch with a simple configuration in which a suction means having a suction port is provided above the lower surface of the upper punch. .
また、 上杵にとつて、 余分な粉体材料 (例えば、 上杵の上面迄到達せず、 雲の ように漂うような粉体材料) は、 直ちに、 吸引口から、 吸引除去されるので、 粉 体材料が、 飛散して、 他の装置部分に付着することがない。 Also, for the upper punch, extra powdery material (for example, The powder material that drifts is immediately sucked and removed from the suction port, so that the powder material does not scatter and adhere to other device parts.
請求項 9に記載の錠剤の製造方法は、 請求項 6〜 8のいずれかに記載の錠剤の 製造方法の、 下杵の上面及び曰の内周壁面に塗布された粉体材料の中、 下杵の上 面及び臼の内周壁面にとって余分な粉体材料を、 臼内に所定の位置まで挿入され た下杵の上面に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける場所と は、 導通しない場所で、 吸引除去す ようにした。 The method for producing a tablet according to claim 9 is the method for producing a tablet according to any one of claims 6 to 8, wherein the powder material applied to the upper surface of the lower punch and the inner peripheral wall is Excessive powder material for the upper surface of the punch and the inner peripheral wall of the mortar, and the location where the powder material dispersed in the air pulsating wave air flow is directly sprayed on the upper surface of the lower punch inserted into the mortar to the specified position. Was removed by suction in places where conduction did not occur.
この錠剤の製造方法では、 下杵の上面及び曰の内周壁面に塗布された粉体材料 の中、 下杵の上面及び曰の内周壁面にとって余分な粉体材料を、 曰内に所定の位 置まで挿入された下杵の上面に、 空気脈動波の気流に分散した粉体材料を直接吹 き付ける場所とは、 導通しない場所で、 吸引除去するようにしているので、 曰内 に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分散した粉体材 料を直接吹き付ける条件に影響を与えることなく、 下杵の上面及び曰の内周壁面 に塗布された粉体材料の中、 下杵の上面及び曰の内周壁面にとって余分な粉体材 料を、 吸引除去することができる。 In this tablet manufacturing method, in the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface, extra powder material for the upper surface of the lower punch and the inner peripheral wall surface is specified in a prescribed manner. The location where the powder material dispersed in the air pulsating wave is directly blown onto the upper surface of the lower punch inserted up to the position is a place where it does not conduct, and it is suctioned and removed. The powder applied to the upper surface of the lower punch and the inner peripheral wall without affecting the conditions for directly blowing the powder material dispersed in the air pulsating air stream onto the upper surface of the lower punch inserted up to the position Excess powder material in the body material, on the upper surface of the lower punch and on the inner peripheral wall can be removed by suction.
尚、 下杵の上面及び曰の内周壁面に塗布された粉体材料の中、 下杵の上面及び 曰の内周壁面にとって余分な粉体材料には、 回転テ一ブルの表面に付着している 粉体材料も含まれる。 In addition, of the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface, excess powder material for the upper surface of the lower punch and the inner peripheral wall surface adheres to the surface of the rotating table. Powder materials are also included.
請求項 1 0に記載の錠剤の製造方法は、 請求項 6〜 9のいずれかに記載の錠剤 の製造方法の、 下杵の上面の曰内の所定の位置が、 下杵の上面が臼内で最下位と なる位置である。 The method for producing a tablet according to claim 10 is the method for producing a tablet according to any one of claims 6 to 9, wherein the predetermined position on the upper surface of the lower punch is the upper surface of the lower punch. Is the lowest position.
この錠剤の製造方法では、 下杵が、 曰内で最下位となる位置で、 下杵の上面及 び曰の内周壁面に、 粉体材料を塗布するようにし、 成形材料を圧縮成形する際に、 成形材料に接触する臼の内周壁面に、 万遍なく、 粉体材料を塗布するようにして いるので、 臼に、 成形材料が付着しない。 In this tablet manufacturing method, a powder material is applied to the upper surface of the lower punch and the inner peripheral wall surface at a position where the lower punch is at the lowest position in the lower punch. In addition, since the powder material is applied evenly to the inner peripheral wall of the mill that comes into contact with the molding material, the molding material does not adhere to the mill.
請求項 1 1 ~ 1 6は、 上杵用の粉体材料の塗布装置の構成を規定する。 Claims 11 to 16 define the configuration of the applicator for the powder material for the upper punch.
即ち、 請求項 1 1に記載の上杵用の粉体材料の塗布装置は、 複数の曰、 複数の 上杵及び複数の下杵を備え、 成形材料充填ポイントにおいて、 下杵が所定の位置 まで挿入された曰内に、 成形材料を、 順次、 充填し、 その後、 圧縮ポイントにお いて、 曰内に充填された成形材料を、 組となる臼、 上杵及び下杵により圧縮成形 して、 錠剤を製造する連続打錠機の、 回転テーブルに設けられた複数の曰と同期 して回転するよう (こされている複数の上杵の下面に、 粉体材料を塗布する、. 上杵 用の粉体材料の塗布装置であって、 複数の上杵の下面の下方に設けられ、 成形材 料充填ポイントの前段部に設けられ、 且つ、 組となる下杵が所定の位置まで挿入 された曰の内周壁面及び下杵の上面へ粉体材料を塗布する下杵用の粉体材料塗布 ポイントとは別の位置に設けられ、 複数の上杵の回転軌道に沿って湾曲するよう に設けられ、 回転移動してくる、 複数の上杵を、 順次、 収容する、 長尺な形状の 上杵収容溝と、 上杵収容溝の底面に、 複数の上杵の回転軌道に沿って設けられ、 上杵収容溝内を移動する複数の上杵の下面に、 空気脈動波の気流に分散された粉 体材料を噴霧するスリット部とを備える。 That is, the powder material application device for an upper punch according to claim 11 includes a plurality of upper punches and a plurality of lower punches, and at a molding material filling point, the lower punch reaches a predetermined position. Within the inserted statement, the molding material was filled in order, and then reached the compression point. In addition, the molding material filled in the box is compression-molded by a pair of mortar, upper punch and lower punch, and synchronized with a plurality of rows provided on a rotary table of a continuous tableting machine that manufactures tablets. The powder material is applied to the lower surface of a plurality of upper punches. The powder material application device for the upper punch is provided below the lower surface of the upper punches. The powder for the lower punch, which is provided at the front part of the molding material filling point and which applies the powder material to the inner peripheral wall surface and the upper surface of the lower punch where the lower punch as a set is inserted to a predetermined position. It is provided at a position different from the body material application point, and is provided so as to be curved along the rotation path of the plurality of upper punches. The upper punch receiving groove and the bottom of the upper punch receiving groove The lower surface of the plurality of upper punch to move the upper punch accommodation groove, and a slit part for spraying the powder material dispersed in airflow pulsating vibration air.
この上杵用の粉体材料の塗布装置では、 上杵の下面に、 空気脈動波の気流に分 散された粉体材料を噴霧する長尺なスリット部を設け、 このスリッ卜部の上方を 上杵が通過する間に、 時間をかけて、 上杵の下面に、 粉体材料を噴霧するように しているので、 重力の関係で、 粉体材料が付着し難い、 上杵の下面に、 粉体材料 を、 ひっつけるようにしているので、 上杵の下面へも、 粉体材料を均一に塗布で きる。 In the powder material applying device for the upper punch, a long slit is provided on the lower surface of the upper punch for spraying the powder material dispersed in the air current of the air pulsating wave. Since the powder material is sprayed on the lower surface of the upper punch over time while the punch passes, the powder material is less likely to adhere to the lower surface of the upper punch due to gravity. Since the powder material is attached to the lower surface of the upper punch, the powder material can be evenly applied.
請求項 1 2に記載の上杵用の粉体材料の塗布装置は、 請求項 1 1に記載の上杵 用の粉体材料の塗布装置が、 スリット部の上方に第 1の吸引手段を、 更に、 備え、 第 1の吸引手段は、 スリット部の領域を覆う大きさの吸引口を有しており、 且つ、 吸引口は、 平面視した場合、 複数の上杵の回転軌道の外周側に沿った形状をして おり、 第 1の吸引手段を駆動すれば、 吸引口の形状により、 スリット部の上方に、 スリット部から吸引口へ向かう気流が発生し、 スリット部に万遍なく、 空気に分 散された粉体材料が供給されるようになっている。 An apparatus for applying a powder material for an upper punch according to claim 12 is an apparatus for applying a powder material for an upper punch according to claim 11, wherein a first suction unit is provided above the slit portion. Further, the first suction means has a suction port large enough to cover the area of the slit portion, and the suction port is provided on the outer peripheral side of the rotation track of the plurality of upper punches when viewed in a plan view. When the first suction means is driven, an airflow from the slit to the suction port is generated above the slit due to the shape of the suction port, and the air is evenly distributed in the slit. The powder material dispersed in the container is supplied.
この上杵用の粉体材料の塗布装置では、 スリット部の上方には、 スリット部の 領域を覆う大きさで、 且つ、 平面視した場合には、 回転テーブルに設けられた複 数の曰の回転軌道の外周側に沿った形状の吸引口を有する第 1の吸引手段が設け られている。 これにより、 第 1の吸引手段を駆動させると、 スリット部の全領域 の上側に、 万遍なく、 下方より上方に向かう気流が発生する。 したがって、 スリ ット部から吹き出した粉体材料は、 スリット部の全領域から、 万遍なく、 下方よ り上方に向かって、 吸引口方向へ移動する。 In the powder material coating device for the upper punch, the upper part of the slit is large enough to cover the area of the slit, and when viewed in a plan view, a plurality of the above-mentioned rotary table is provided on the rotary table. A first suction means having a suction port shaped along the outer peripheral side of the rotating orbit is provided. As a result, when the first suction means is driven, an airflow is generated uniformly above the entire region of the slit portion and directed upward from below. Therefore, pickpocket The powder material blown out from the slot moves from the lower part to the upper part of the entire slit area in the suction port direction.
これにより、 上杵収容溝内を移動してくる、 次の曰に対応 て設けられた上杵 の下面には、 上杵が、 長尺なスリット部の起端部から終端部まで移動する間に、 万遍なく、 下方より上方に向かってくる粉体材料が、 下面に概ね垂直方向に衝突 し続けることになる。 As a result, the upper punch, which moves in the upper punch receiving groove, is provided on the lower surface of the upper punch provided in accordance with the following statement, while the upper punch moves from the start to the end of the long slit. In addition, the powder material coming from above and below from all over will continue to collide with the lower surface in a substantially vertical direction.
このようにして、 粉体材料が、 重力の関係で付着し難い、 上杵の下面へ、 時間 をかけて、 スリット部の全領域から、 万遍なく、 下方より上方に向かって吹き出 す粉体材料を、 ひっつけるようにしているので、 上杵の下面へも、 粉体材料を均 —に塗布できる。 In this way, the powder material, which hardly adheres due to gravity due to gravity, takes a long time and blows out from the entire area of the slit to the lower part of the upper punch from above to below. Since the material is attached, the powder material can be evenly applied to the lower surface of the upper punch.
また、 空気に混和した粉体材料を、 回転テーブルの回転方向と逆方向に流す構 成にしたので、 空気に混和した粉体材料を、 回転テーブルの回転方向と順方向に 流すようにしているという構成にしたものに比べ、 上杵の下面へ、 粉体材料を効 率良く衝突させることができる。 - この上杵用の粉体材料の塗布装置では、 このようにして、 効率良く、 上杵の下 面へ、 粉体材料を均一に塗布できる。 In addition, since the powder material mixed with air is made to flow in the direction opposite to the rotation direction of the turntable, the powder material mixed with air is made to flow in the forward direction with the rotation direction of the turntable. The powder material can be made to efficiently collide with the lower surface of the upper punch as compared with the configuration described above. -In this way, the powder material applying device for the upper punch can efficiently and uniformly apply the powder material to the lower surface of the upper punch.
このため、 この上杵用の粉体材料の塗布装置を用いれば、 その下面に、 万遍な く、 粉体材料が塗布された上杵と、 その上面に、 万遍なく、 粉体材料が塗布され た下杵と、 その内周壁面に、 万遍なく、 粉体材料が塗布された臼とを用いて錠剤 を製造できるので、 粉# ^料として、 滑沢剤を用いた場合には、 杵ゃ臼に、 ギシ ツキを生じることなく、 且つ、 打錠障害 (ラミネ一ティング、 キヤヅビング、 ス テイツキング等) を生じることなく、 連続打錠が可能になる。 これにより、 生産 ペースで、 外部滑沢錠剤の製造が可能になる。 For this reason, if the powder material applying device for the upper punch is used, the lower surface is uniformly coated with the powder material, and the upper surface is uniformly coated with the powder material. Tablets can be manufactured using the lower punch that has been applied and the mortar that has been applied with powder material evenly on the inner peripheral wall, so if a lubricant is used as the powder, Thus, continuous tableting can be performed without causing any stickiness in the punch and die, and without causing tableting troubles (laminating, caving, staking, etc.). This allows the production of external lubricating tablets at the production pace.
また、 粉体材料として、 表面改質剤を用いた場合には、 杵ゃ曰に、 表面改質剤 を均一に塗布できるので、 この上杵用の粉体材料の塗布装置を用いれば、 表面改 質剤が均一に塗布された杵と曰とを用いて、 錠剤を製造できるので、 錠剤の表面 に表面改質剤が均一に塗布された錠剤を製造できるようになる。 Also, when a surface modifier is used as the powder material, the surface modifier can be uniformly applied to the punches, and if the powder material application device for the upper punch is used, the surface Since a tablet can be manufactured using a punch with the modifying agent uniformly applied, it is possible to manufacture a tablet in which the surface modifier is uniformly applied to the surface of the tablet.
請求項 1 3に記載の上杵用の粉体材料の塗布装置は、 請求項 1 1又は請求項 1 2に記載の上杵用の粉体材料の塗布装置の、 スリット部の幅が、 錠剤に形成する 割線や刻印の領域の幅に概ね一致するようにされている。 An apparatus for applying a powder material for an upper punch according to claim 13, wherein the width of a slit portion of the apparatus for applying a powder material for an upper punch according to claim 11 or 12 is a tablet. Form The width is approximately equal to the width of the area of the score line or the mark.
一般に、 錠剤には、 割線や刻印を設けた部分、 即ち、 複雑な凹凸が形成されて いる部分で、 ラミネーティング、 キヤヅビング、 スティツキ、ング等が生じ易い。. また、 錠剤に、 表面改質剤を塗布する場合には、 錠剤の、 割線や刻印を設けた 部分、 即ち、 複雑な凹凸が形成されている部分に、 表面改質剤が、 塗布され難い。 この上杵用の粉体材料の塗布装置では、 スリット部の幅を、 錠剤に形成する割 線や刻印の領域の幅に概ね一致するようにしているので、 上杵収容溝内を移動し てくる、 上杵の下面の、 割線や刻印を形成する部分、 即ち、 複雑な凸部が形成さ れている部分を中心にして、 上杵の下面に、 粉体材料が塗布される。 In general, laminating, caving, sticking, sticking, and the like are likely to occur in a portion of a tablet provided with a score line or an engraving, that is, a portion having complicated irregularities. In addition, when applying a surface modifier to tablets, it is difficult to apply the surface modifier to the part of the tablet where the score line or marking is provided, that is, the part where complicated irregularities are formed. . In this powder material applicator for the upper punch, the width of the slit is made to substantially match the width of the area of the score line or the mark formed on the tablet. The powder material is applied to the lower surface of the upper punch, centering on the part of the lower surface of the upper punch, which forms the score lines and markings, that is, the part where the complex protrusions are formed.
このように、 この上杵用の粉体材料の塗布装置では、 上杵の下面の、 割線や刻 印を形成する部分に、 十分に且つ均一に、 粉体材料を塗布できるので、 粉体材料 として、 滑沢剤を用いた場合には、 錠剤の、 割線や刻印を設けた部分、 即ち、 複 雑な凹凸が形成されている部分で、 ラミネ一ティング、 キヤヅビング、 ステイツ キングを生じること無く、 錠剤を製造することができる。 As described above, in the powder material applying device for the upper punch, the powder material can be sufficiently and uniformly applied to a portion of the lower surface of the upper punch where a score line or an engraving is formed. In the case where a lubricant is used, it is possible to avoid laminating, caving, and statusing in the part of the tablet where the score line or marking is provided, that is, the part where the complex unevenness is formed. Tablets can be manufactured.
したがって、 この装置を用いれば、 従来は、 生産ベースで製造することが難し かった、 割線や刻印を設けた外部滑沢錠剤を、 生産ペースで製造することができ るようになる。 Therefore, if this device is used, it will be possible to manufacture external lubricating tablets provided with score lines and stamps at a production pace, which was conventionally difficult to manufacture on a production basis.
また、 この上杵用の粉体材料の塗布装置を用いれば、 従来の粉体材料の塗布装 置では、 粉体材料を塗布するのが困難であった、 上杵の下面の、 割線や刻印を形 成する部分へも、 十分に且つ均一に、 粉体材料を塗布することができるので、 粉 体材料として、 表面改質剤を用いた場合には、 従来、 製造するのが困難であった、 割線や刻印が設けられた部分にも、 均一に、 表面改質剤が塗布された錠剤を製造 することができるようになる。 Also, if the powder material applying device for the upper punch is used, it is difficult to apply the powder material using the conventional powder material applying device. The powder material can be applied sufficiently and evenly to the part that forms the powder, and if a surface modifier is used as the powder material, it has conventionally been difficult to manufacture the powder material. In addition, it becomes possible to manufacture a tablet uniformly coated with a surface modifying agent even at a portion where a score line or a mark is provided.
請求項 1 4に記載の上杵用の粉体材料の塗布装置は、 請求項 1 1 ~ 1 3のいず れかに記載の上杵用の粉体材料の塗布装置の、 スリット部の形状が、 ジグザグ形 状にされている。 The apparatus for applying a powder material for an upper punch according to claim 14 is a shape of a slit portion of the apparatus for applying a powder material for an upper punch according to any one of claims 11 to 13. Are zigzag shaped.
これにより、 上杵収容溝内を移動してくる、 上杵は、 スリット部が、 複数の上 杵の回転軌道に沿って、 ただ単に湾曲しているものに比べ、 上杵収容溝内を移動 する際に、 より長いスリット部を通過したことになるので、 尚一層、 上杵の下面 に、 十分且つ均一こ、 粉体材料が塗布される。 This allows the upper punch to move in the upper punch receiving groove. The upper punch moves in the upper punch receiving groove as compared to a slit whose slit part is simply curved along the rotation path of the multiple upper punches. The lower slit of the upper punch, because it has passed through the longer slit The powder material is sufficiently and uniformly applied.
これにより、 粉体材料として、 滑沢剤を用いた場合には、 錠剤の、 割線や刻印 を設けた部分、 即ち、 複雑な凹凸が形成されている部分で、、ラミネーティング、 キヤヅビング、 ステイツキングをより一層生じること無く、 錠剤を製造すること ができる。 したがって、 この装置を用いれば、 割線や刻印を設けた外部滑沢錠剤 を、 より一層高い生産効率で製造することができるようになる。 As a result, when a lubricant is used as a powder material, laminating, caving, and statusing are performed on the tablet at the part where the score line or marking is provided, that is, at the part where complicated unevenness is formed. Tablets can be produced without further occurrence of Therefore, if this device is used, an external lubricating tablet provided with a score line and a stamp can be manufactured with higher production efficiency.
また、 この上杵用の粉体材料の塗布装置を用いれば、 上杵の下面の、 割線や刻 印を形成する部分へも、 十分に且つ均一に、 粉 料を塗布することができるの で、 粉体材料として、 表面改質剤を用いた場合には、 割線や刻印が設けられた部 分にも、 均一に、 表面改質剤が塗布された錠剤を、 より一層高い生産効率で製造 することができるようになる。 In addition, if the powder material applying device for the upper punch is used, the powder can be sufficiently and uniformly applied to a portion of the lower surface of the upper punch where a score line or a mark is formed. If a surface modifier is used as the powder material, tablets with the surface modifier applied uniformly at the part where the score line or marking is provided can be manufactured with even higher production efficiency. Will be able to
請求項 1 5に記載の上杵用の粉体材料の塗布装置は、 請求項 1 1〜 1 4のいず れかに記載の上杵用の粉体材料の塗布装置の、 スリット部の上方に、 所定の孔径 を有するメッシュ手段を設けた。 An apparatus for applying a powder material for an upper punch according to claim 15 is provided above the slit portion of the apparatus for applying a powder material for an upper punch according to any one of claims 11 to 14. Further, a mesh means having a predetermined hole diameter was provided.
上杵の下面に、 粒径の異なる粉体材料 (例えば、 大粒の粉体粒子) が付着する と、 このことが原因して、 打錠が困難になったり、 製造される錠剤の表面に、 粉 体材料を均一に塗布できなくなるため、 上杵の下面には、 可能な限り、 粒径の揃 つたる粉体材料を均一に塗布する必要がある。 If powder materials with different particle sizes (for example, large powder particles) adhere to the lower surface of the upper punch, tableting becomes difficult due to this, and the surface of the manufactured tablets becomes Since it becomes impossible to apply the powder material uniformly, it is necessary to apply the powder material having a uniform particle size to the lower surface of the upper punch as uniformly as possible.
この上杵用の粉体材料の塗布装置では、 スリット部の上方に、 所定の孔径を有 するメッシュ手段を設けて、 所定粒径以上の粉 料を、 このメッシュ手段でキ ャツチすることで、 上杵の下面に大粒の粉体材料が付着するのを阻止できるよう にしている。 In the powder material application device for the upper punch, a mesh means having a predetermined hole diameter is provided above the slit portion, and a powder having a predetermined particle size or more is catched by the mesh means. Large powder material is prevented from adhering to the lower surface of the upper punch.
この結果、 上杵の下面に、 粒径の揃った粉体材料を、 均一に塗布できる。 As a result, a powder material having a uniform particle size can be uniformly applied to the lower surface of the upper punch.
したがって、 この上杵用の粉体材料の塗布装置を用いれば、 打錠が困難になる ことなく、 且つ、 表面に、 粉体材料を均一に塗布された錠剤を容易に製造できる。 また、 メッシュ手段により、 スリット部から第 1の吸引手段の吸引口へ流れる 気流が整流されるので、 これによつて、 上杵の下面に、 粉体材料が、 一層、 均一 に塗布される。 Therefore, by using the powder material applicator for the upper punch, it is possible to easily produce a tablet on which the powder material is uniformly applied on the surface without making the tableting difficult. Further, since the air flow flowing from the slit portion to the suction port of the first suction means is rectified by the mesh means, the powder material is more uniformly applied to the lower surface of the upper punch.
請求項 1 6に記載の上杵用の粉体材料の塗布装置は、 請求項 1 1〜1 5のいず れかに記載の上杵用の粉体材料の塗布装置の、 スリット部の代わりに、 上杵収容 溝の底面に、 複数の上杵の回転軌道に沿って、 上杵収容溝内を移動する複数の上 杵の下面に、 空気脈動波の気流に分散された粉体材料を噴霧ヽす'る、 複数の噴射孔 を配置した。 An apparatus for applying a powder material for an upper punch according to claim 16 is any of claims 11 to 15 In the powder coating device for the upper punch described in the crab, instead of the slit, move in the upper punch receiving groove along the rotation path of the multiple upper punches on the bottom surface of the upper punch receiving groove On the lower surface of the plurality of upper punches, a plurality of injection holes for spraying the powder material dispersed in the air current of the air pulsating wave were arranged.
この上杵用の粉体材料の塗布装置では、 スリット部の代わりに、 上杵収容溝の 底面に、 複数の上杵の回転軌道に沿って、 上杵収容溝内を移動する複数の上杵の 下面に、 空気脈動波の気流に分散された粉体材料を噴霧する、 複数の噴射孔を配 置したので、 粉体材料が、 複数の噴射孔の各々から噴霧される際に、 気流に、 あ る種の整流効果が得られる。 In the powder material application device for the upper punch, instead of the slit portion, a plurality of upper punches that move in the upper punch receiving groove along the rotation path of the upper punches on the bottom surface of the upper punch receiving groove. A plurality of injection holes for spraying the powder material dispersed in the air current of the air pulsating wave are arranged on the lower surface of the nozzle, so that when the powder material is sprayed from each of the plurality of injection holes, However, a certain rectifying effect can be obtained.
これにより、 重力との関係で、 粉体材料が付着し難い、 上杵の下面に、 粉体材 料が、 均一に塗布される。 As a result, the powder material hardly adheres due to the gravity, and the powder material is uniformly applied to the lower surface of the upper punch.
請求項 1 7〜2 2は、 下杵用の粉体材料の塗布装置の構成を規定する。 Claims 17 to 22 define the configuration of the powder material application device for the lower punch.
尚、 本明細書で用いる用語、 「下杵用の粉体材料の塗布装置」 は、 下杵の上面 のみならず、 下杵が所定の位置まで挿入されている曰の、 下杵の上面より上方の 内周壁面へも、 粉体材料を塗布する装置を意味する。 In addition, the term "application device for powder material for lower punch" used in the present specification means that not only the upper surface of the lower punch but also the lower punch is inserted to a predetermined position. It means a device that applies powder material to the upper inner peripheral wall.
即ち、 請求項 1 7に記載の下杵用の粉体材料の塗布装置は、 複数の曰、 複数の 上杵及び複数の下佇を備え、 成形材料充填ポイントにおいて、 下杵が所定の位置 まで挿入された臼内に、 成形材料を、 順次、 充填し、 その後、 圧縮ポイントにお いて、 曰内に充填された成形材料を、 組となる臼、 上杵及び下杵により圧縮成形 して、 錠剤を製造する連続打錠機の、 複数の曰が周方向に設けられた回転テ一ブ ル上に固定的に設けられ、 回転テーブルに設けられた複数の曰と同期して回転す るようにされている複数の下杵の上面に、 粉体材料を塗布する、 下杵用の粉^ ί 料の塗布装置であって、 成形材料充填ポイントの前段部に設けられ、 且つ、 組と なる上杵の下面に粉体材料を塗布する上杵用の粉体材料塗布ボイントとは別の位 置に設けられ、 回転移動してくる、 下杵が所定の位置まで挿入された臼を、 順次、 収容し、 曰内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分 散された粉体材料を吹き付ける排出口を、 回転テーブルに対向する表面に設けた。 この下杵用の粉体材料の塗布装置では、 空気脈動波の気流に分散された粉体材 料を排出口から、 曰内に所定の位置まで挿入された下杵の上面に吹き付けるよう にしているので、 空気脈動波の振幅により、 重力との関係で、 下杵の上面に余分 に、 粉体材料が堆積しても、 空気脈動波により、 そのような余分な粉体材料が、 下杵の上面から吹き飛ばされる結果、 ·重力との関係で、 余分な粉体材料が堆積し がちな下杵の上面に、 粉体材料を均一に塗布できる。 That is, the powder material applying apparatus for a lower punch according to claim 17 includes a plurality of upper punches and a plurality of lower stands, and at a molding material filling point, the lower punch reaches a predetermined position. The molding material is sequentially filled into the inserted mortar, and then, at the compression point, the molding material filled therein is compression-molded by a pair of mortar, upper punch and lower punch, In a continuous tableting machine that manufactures tablets, a plurality of plates are fixedly mounted on a rotating table provided in the circumferential direction, and rotate in synchronization with a plurality of plates provided on a rotating table. A powder material application device for a lower punch, which applies a powder material to the upper surfaces of a plurality of lower punches provided in the same manner, which is provided at a front stage of a molding material filling point and forms a set. A different position from the powder material application point for the upper punch, which applies the powder material to the lower surface of the upper punch The mortar with the lower punch inserted to the predetermined position, which is provided and rotated, is sequentially accommodated, and the upper surface of the lower punch inserted to the predetermined position is divided into air pulsating waves. An outlet for spraying the scattered powder material was provided on the surface facing the rotary table. In the powder material application device for the lower punch, the powder material dispersed in the air current of the air pulsating wave is sprayed from the outlet onto the upper surface of the lower punch inserted into a predetermined position inside the lower punch. Due to the amplitude of the air pulsation wave, even if extra powder material accumulates on the upper surface of the lower punch due to gravity, due to the air pulsation wave, such extra powder material becomes As a result of being blown off from the upper surface of the lower punch, the powder material can be uniformly applied to the upper surface of the lower punch where excess powder material tends to accumulate due to gravity.
且つ、 下杵の上面から吹き飛ばされた粉体材料は、 臼の内周壁面に付着するの で、 臼の内周壁面にも、 粉体材料を均一に塗布できる。 The powder material blown off from the upper surface of the lower punch adheres to the inner peripheral wall surface of the mortar, so that the powder material can be uniformly applied to the inner peripheral wall surface of the mortar.
請求項 1 8に記載の下杵用の粉体材料の塗布装置は、 請求項 1 7に記載の下杵 用の粉体材料の塗布装置の、 排出口が、 排出口の真下に位置する曰内に所定の位 置まで挿入されている下杵の上面の概ね中心部に、 概ね垂直方向を向くように設 けられている。 The powder material applying device for a lower punch according to claim 18 is configured such that the outlet of the powder material applying device for the lower punch according to claim 17 is located directly below the outlet. The lower punch is inserted into the inside of the lower punch at a predetermined position, and is provided at a substantially central portion of the upper surface so as to face a substantially vertical direction.
この下杵用の粉体材料の塗布装置では、 本体を貫通するように設けられた貫通 孔の排出口より、 曰内に所定の位置まで挿入された下杵の上面に、 空気脈動波に 混和された粉体材料を直接吹き付けるようにしている。 これにより、 下杵の上面 に、 付着したり、 堆積したりし易い、 余分な粉^料が、 空気脈動波により、 下 杵の上面から吹き飛ばされる結果、 下杵の上面に、 粉体材料が均一に塗布される。 同様に、 空気脈動波により、 曰の内周壁面に余分に付着している粉体材料も吹 き飛ばされるので、 曰の内周壁面に、 粉体材料が均一に塗布される。 In this powder material application device for lower punches, the air pulsation wave is mixed with the upper surface of the lower punch inserted to a predetermined position from the outlet of the through hole provided to penetrate the main body. The sprayed powder material is directly sprayed. As a result, excess powder that easily adheres or accumulates on the upper surface of the lower punch is blown off from the upper surface of the lower punch by an air pulsating wave, so that the powder material is formed on the upper surface of the lower punch. Uniformly applied. Similarly, the powder material adhering extra to the inner peripheral wall is also blown off by the air pulsating wave, so the powder material is uniformly applied to the inner peripheral wall.
請求項 1 9に記載の下杵用の粉体材料の塗布装置は、 請求項 1 7又は請求項 1 8に記載の下杵用の粉体材料の塗布装置の、 回転テーブルに対向する表面の、 排 出口の後段部に、 更に、 下杵用の粉体材料の塗布装置内に収容され、 排出口から、 下杵及び臼に吹き付けられ、 下杵及び臼に余分に付着している粉体材料、 及び回 転テーブル上の余分な粉体材料を除去する第 2の吸引手段を設けた。 An apparatus for applying a powder material for a lower punch according to claim 19 is a device for applying a powder material for a lower punch according to claim 17 or claim 18, which has a surface facing a rotary table. In the latter part of the discharge outlet, the powder is further housed in a powder material application device for the lower punch, and is sprayed from the discharge port onto the lower punch and the die, and the powder that is excessively attached to the lower punch and the die. Second suction means was provided for removing the material and excess powder material on the rotating table.
この下杵用の粉体材料の塗布装置では、 第 2の吸引手段を設け、 下杵及び臼に 余分に付着している粉体材料、 及び回転テーブル上の余分な粉体材料を除去する ようにしている。 In the powder material applying device for the lower punch, a second suction means is provided to remove the excess powder material adhering to the lower punch and the die and the excess powder material on the rotary table. I have to.
したがって、 例えば、 第 2の吸引手段の下流位置に、 成形材料充填部を設けれ ば、 下杵及び臼により形成される空間内に、 成形材料を充填する工程において、 下杵及び曰に余分に付着している粉体材料、 及び、 回転テ一ブル上の余分な粉体 材料が、 成形材料中に、 混入することを防ぐことができる。 これにより、 尚一層、 内部に、 滑沢剤を含むことの無い、 外部滑沢錠剤を、 効 率よく製造することができる。 Therefore, for example, if a molding material filling portion is provided at a position downstream of the second suction means, in the step of filling the molding material into the space formed by the lower punch and the die, the lower punch and the extra The adhering powder material and excess powder material on the rotating table can be prevented from being mixed into the molding material. As a result, an external lubricating tablet that does not contain a lubricant therein can be produced more efficiently.
また、 錠剤内部に、 表面改質剤が混入されていない、 表面改質錠剤の製造が可 In addition, it is possible to manufacture surface-modified tablets in which no surface modifier is mixed inside the tablets.
、, ,,
能になる。 It will work.
請求項 2 0に記載の下杵用の粉体材料の塗布装置は、 請求項 1 9に記載の下杵 用の粉体材料の塗布装置の、 第 2の吸引手段は、 回転テーブルに設けられる、 複 数の曰の回転軌道に概ね直交するように、 複数の曰の各々及びそれらの周辺を力 バ一できる長さのスリット状の吸引口を有している。 The powder material applying device for lower punches according to claim 20 is the powder material applying device for lower punches according to claim 19, wherein the second suction means is provided on a rotary table. It has a slit-shaped suction port that is long enough to force each of the plurality of objects and their surroundings so as to be substantially orthogonal to the plurality of said orbits.
この下杵用の粉体材料の塗布装置では、 第 2の吸引手段の吸引口を、 複数の曰 の回転軌道に直交するように、 複数の曰の各々及びそれらの周辺をカバーできる 長さで形成しているので、 下杵及び曰に余分に付着している粉体材料、 及び回転 テーブル上の余分な粉体材料を、 第 2の吸引手段を駆動させることにより効率よ く除去することができる。 In this powder material application device for lower punches, the suction port of the second suction means is provided with a length capable of covering each of the plurality of parts and the periphery thereof so as to be orthogonal to the plurality of rotation paths. Because of the formation, it is possible to efficiently remove the powder material adhering to the lower punch and the surface and the excess powder material on the rotary table by driving the second suction means. it can.
これにより、 更に、 一層、 内部に、 滑沢剤を含むことの無い、 外部滑沢錠剤を、 効率よく製造することができる。 This makes it possible to efficiently produce an external lubricating tablet that does not further contain a lubricant.
また、 錠剤内部が、 表面改質剤により、 一切、 汚染されていない、 表面改質錠 剤の製造が可能になる。 In addition, it is possible to manufacture surface-modified tablets that are not contaminated at all by the surface modifier inside the tablet.
請求項 2 1に記載の下杵用の粉体材料の塗布装置は、 請求項 2 0に記載の下杵 用の粉体材料の塗布装置の、 第 2の吸引手段の吸引口は、 少なくとも、 排出口が 設けられている位置から、 前記回転テーブルに設けられる、 複数の臼の各々の直 径より、 離れた位置に設けられている。 The powder material application device for lower punches according to claim 21 is the powder material application device for lower punches according to claim 20, wherein the suction port of the second suction means is at least: The plurality of dies, which are provided on the rotary table, are located farther from the diameter of each of the plurality of dies provided from the position where the discharge port is provided.
この下杵用の粉体材料の塗布装置では、 下杵の上面及び臼の内周壁面に塗布さ れた粉体材料の中、 下杵の上面及び曰の内周壁面にとって余分な粉体材料を、 曰 内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分散した粉体 材料を直接吹き付ける場所とは、 導通しない場所で、 吸引除去するようにしてい るので、 臼内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分 散した粉体材料を直接吹き付ける条件に影響を与えることなく、 下杵の上面及び 曰の内周壁面に塗布された粉体材料の中、 下杵の上面及び曰の内周壁面にとって 余分な粉体材料を、 吸引除去することができる。 尚、 下杵の上面及び曰の内周壁面に塗布された粉体材料の中、 下杵の上面及び 曰の内周壁面にとって余分な粉体材料には、 回転テーブルの表面に付着している 粉体材料も含まれる。 、- 請求項 2 2に記載の下杵用の粉体材料の塗布装置は、 請求項 1 7〜2 1のいず れかに記載の下杵用の粉体材料の塗布装置の、 回転テーブルに対向する表面の、 排出口の前段部に、 更に、 複数の下杵の上面、 複数の曰内及び複数の曰の周辺に 付着している成形材料を、 順次、 除去するために設けられ、 複数の曰の回転軌道 に概ね直交するように、 且つ、 複数の臼の各々の直径と概ね一致する幅か、 それ よりやや大きい幅のスリット状の成形材料吸引口を有する第 3の吸引手段を設け た。 In the powder material applying device for the lower punch, the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface of the lower punch is excess in the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface of the die. The point where the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface of the lower punch inserted to a predetermined position in the inside is said to be sucked and removed in a place where it does not conduct. The upper surface of the lower punch and the inner wall of the lower punch are not affected by the condition that the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface of the lower punch inserted to the predetermined position in the mortar. Excess powder material on the upper surface of the lower punch and on the inner peripheral wall of the applied powder material can be removed by suction. In addition, of the powder material applied to the upper surface of the lower punch and the inner peripheral wall, excess powder material for the upper surface of the lower punch and the inner peripheral wall adheres to the surface of the rotary table. Powder materials are also included. A rotary table of the powder material applying apparatus for a lower punch according to any one of claims 17 to 21. Provided in order to sequentially remove the molding material attached to the upper surface of the plurality of lower punches, the inside of the plurality of arms and the periphery of the plurality of arms, at the front part of the discharge port on the surface facing the A third suction means having a slit-shaped molding material suction port having a width substantially equal to or slightly larger than a diameter of each of the plurality of dies so as to be substantially orthogonal to the plurality of rotation orbits is provided. Provided.
この下杵用の粉体材料の塗布装置では、 滑沢剤を排出する排出口の前段部に、 成形材料吸引口を有する第 3の吸引手段を設け、 滑沢剤を噴霧する前に、 曰の内 周壁面及び下杵の上面を清浄し、 前工程で使用した成形材料や滑沢剤が、 次工程 の錠剤中に混入することがないようにしているので、 錠剤を連続的に製造しても、 錠剤間で、 滑沢剤の使用量等に不均一を生じない。 これにより、 同じ規格の錠剤 を連続的に製造できる。 In the powder material application device for the lower punch, a third suction means having a molding material suction port is provided at a front stage of the discharge port for discharging the lubricant, and before spraying the lubricant, The inner peripheral wall surface and the upper surface of the lower punch are cleaned to prevent the molding material and lubricant used in the previous process from being mixed into the tablet in the next process. However, there is no unevenness in the amount of lubricant used between tablets. This enables continuous production of tablets of the same specification.
請求項 2 3〜3 4は、 下杵用の粉体材料の塗布装置と上杵用の粉体材料の塗布 装置とを組み合わせた粉体材料の塗布装置の構成を規定する。 Claims 23 to 34 define the configuration of a powder material application device in which a powder material application device for the lower punch and an application device for the powder material for the upper punch are combined.
即ち、 請求項 2 3に記載の粉体材料の塗布装置は、 連続打錠機の、 複数の曰が 周方向に設けられた回転テーブル上の所定の位置に固定的に設けるようにされた 粉体材料の塗布装置であって、 下杵用の粉体材料の塗布装置と、 下杵用の粉体材 料の塗布装置に、 回転テーブルの回転方向とは逆方向の位置に接続された上杵用 の粉体材料の塗布装置とを備え、 下杵用の粉体材料の塗布装置及び上杵用の粉体 材料の塗布装置の各々は、 回転テーブルが、 摺動できるように、 各々の、 回転テ 一ブルに対向する側の表面が、 滑らかな表面にされており、 下杵用の粉体材料の 塗布装置は、 その外表面に、 空気脈動波に混和された滑沢剤等の粉体材料を送り 込む粉体材料導入口が設けられており、 粉体材料導入口に送り込まれた粉体材料 は、 下杵用の粉体材料の塗布装置を貫通するように設けられた貫通孔を通って、 回転テ一ブルに対向する側の表面に送られ、 貫通孔の回転テーブルに対向する側 の表面側の排出口より空気ととも排出された粉^料は、 下杵用の粉体材料の塗 布装置に収容されている、 臼の内周面、 及び、 曰内に所定の深さまで挿入された 下杵の上面に吹き付けられるようになつており、 上杵用の粉体材料の塗布装置は、 回転テーブルに対向する側の表面から上杵用の粉体材料の塗布装置を貫通するよ うに、 且つ、 複数の上杵の回転軌道に沿うように湾曲した長尺なスリット部と、 上杵用の粉体材料め塗布装置の外表面側に設けられた、 スリツト部の領域を含む ように、 且つ、 回転移動してくる複数の上杵を収容するために設けられた杵収容 溝とを備え、 複数の上杵の回転軌道に沿うように湾曲して設けられており、 上杵 収容溝の幅は、 複数の上杵の各々の外径と一致する幅か、 それよりやや大きい幅 にされており、 上杵収容溝に収容されている、 上杵の下面は、 スリット部から供 給される粉# ^料に曝され易くなつている一方、 上杵収容溝に収容されている、 上杵の側周には、 粉体材料が付着し難いようにされて構成されており、 且つ、 下 杵用の粉体材料の貫通孔の回転テーブルに対向する側の表面側の排出口より、 空 気ととも、 下杵用の粉体材料の塗布装置に収容されている、 曰の内周面、 及び、 曰内に所定の深さまで挿入された下杵の上面に吹き付けられた粉体材料は、 更に、 上杵用の粉体材料の塗布装置に設けられたスリット部に供給されるようになって いる。 In other words, the powder material application device according to claim 23 is a powder compression device that is provided in a continuous tableting machine at a predetermined position on a rotary table provided in a circumferential direction. A body material application device, which is connected to a powder material application device for the lower punch and a powder material application device for the lower punch at a position opposite to the rotation direction of the rotary table. A powder material application device for the punch and a powder material application device for the lower punch and a powder material application device for the upper punch, respectively, so that the rotary table can slide. The surface on the side facing the rotary table is made a smooth surface, and the coating device for the powder material for the lower punch is equipped with an outer surface, such as a lubricant mixed with air pulsation waves. A powder material inlet for feeding the powder material is provided, and the powder material fed into the powder material inlet is Through the through holes provided to penetrate the coating apparatus of the powder material for punch, sent to the surface on the side facing the rotation Te one table, facing the rotary table of the through hole The powder discharged together with air from the discharge port on the front side of the surface of the die is contained in the powder material coating device for the lower punch, the inner peripheral surface of the mortar, and to a specified depth. It is designed to be sprayed on the upper surface of the inserted lower punch, and the powder material application device for the upper punch penetrates the powder material application device for the upper punch from the surface opposite to the rotary table Thus, it includes a long slit portion curved so as to follow the rotation trajectory of the plurality of upper punches, and a slit portion region provided on the outer surface side of the powder material application device for the upper punch. And a punch accommodation groove provided for accommodating a plurality of upper punches rotating and moving, and is provided so as to be curved along the rotation path of the plurality of upper punches. The width of the receiving groove should be equal to or slightly larger than the outer diameter of each of the upper punches. The lower surface of the upper punch housed in the upper punch receiving groove is easily exposed to the powder supplied from the slit, while the lower surface of the upper punch is stored in the upper punch receiving groove. The powder material is hardly attached to the side circumference of the punch, and the through hole of the powder material for the lower punch is formed through a discharge port on the surface side facing the rotary table. The powder material sprayed on the inner peripheral surface of the lower punch and the upper surface of the lower punch inserted to the specified depth, which is contained in the powder material application device for the lower punch together with the air Is further supplied to a slit provided in a powder material application device for the upper punch.
この粉体材料の塗布装置では、 下杵用の粉体材料の塗布装置に設けられた貫通 孔の排出口より、 臼内に所定の位置まで挿入された下杵の上面に、 空気脈動波に 混和された粉体材料を直接吹き付けるようにしている。 これにより、 下杵の上面 に、 付着したり、 堆積したりし易い、 余分な粉^"料が、 空気脈動波により、 下 杵の上面から吹き飛ばされる結果、 下杵の上面に、 粉体材料が均一に塗布される。 同様に、 空気脈動波により、 曰の内周壁面に余分に付着している粉体材料も吹 き飛ばされるので、 臼の内周壁面に、 粉体材料が均一に塗布される。 In this powder material application device, the air pulsation wave is applied to the upper surface of the lower punch inserted into the mortar to a predetermined position from the outlet of the through hole provided in the powder material application device for the lower punch. The mixed powder material is directly sprayed. As a result, excess powder, which easily adheres or accumulates on the upper surface of the lower punch, is blown off from the upper surface of the lower punch by an air pulsating wave. Similarly, the air pulsating wave also blows off excess powder material on the inner peripheral wall, so that the powder material is evenly distributed on the inner peripheral wall of the mortar. Applied.
更に、 この粉体材料の塗布装置では、 下杵用の粉体材料の塗布装置に上杵用の 粉体材料の塗布装置を回転テーブルの回転方向と逆方向に接続し、 下杵用の粉体 材料の貫通孔の回転テ一ブルに対向する側の表面側の排出口より、 空気ととも、 下杵用の粉体材料の塗布装置に収容されている、 臼の内周面、 及び、 臼内に所定 の深さまで挿入された下杵の上面に吹き付けられた粉体材料は、 更に、 上杵用の 粉体材料の塗布装置に設けられたスリット部に供給するようにしている。 Further, in this powder material applying device, the powder material applying device for the upper punch is connected to the powder material applying device for the lower punch in a direction opposite to the rotation direction of the rotary table, and the powder for the lower punch is connected. The inner peripheral surface of the mortar, which is housed in a powder material application device for the lower punch, together with air, from the discharge port on the surface side of the through hole of the body material facing the rotary table, and The powder material sprayed on the upper surface of the lower punch inserted into the mortar to the predetermined depth further The powder material is supplied to a slit provided in a coating device.
従って、 空気脈動波により、 下杵の上面及び/又は曰の内周壁面より吹き飛ば された余分な粉体材料は、 空気に混和された状態で、 回転テ .ブルの回転方向と. 逆方向 (上流側) に送られ、 スリット部から放出される。 Therefore, the excess powder material blown off from the upper surface of the lower punch and / or the inner peripheral wall surface by the air pulsating wave is mixed with the air, and in a state opposite to the rotating direction of the rotating table. (Upstream side) and released from the slit.
そして、 この粉体材料の塗布装置では、 上杵用の粉体材料の塗布装置には、 長 尺なスリット部の領域を含むように、 回転移動してくる、 複数の上杵を収容する ための、 上杵収容溝を設けているので、 上杵収容溝内を移動してくる、 次の臼に 対応して設けられた上杵の下面には、 上杵が、 長尺なスリット部の起端部から終 端部まで移動する間に、 万遍なく、 下方より上方に向かってくる粉体材料が、 下 面に概ね垂直方向に衝突し続けることになる。 In the powder material coating device, the powder material coating device for the upper punch contains a plurality of upper punches that rotate and move so as to include a long slit region. Because the upper punch receiving groove is provided, the upper punch that moves in the upper punch receiving groove, on the lower surface of the upper punch While moving from the start to the end, the powder material coming from above and below from all over will continue to collide with the lower surface in a substantially vertical direction.
このようにして、 粉体材料が、 重力の関係で付着し難い、 上杵の下面へ、 時間 をかけて、 粉体材料を、 ひっつけるようにしているので、 上杵の下面へも、 粉体 材料を均一に塗布できる。 In this way, the powder material adheres to the lower surface of the upper punch, which is hard to adhere due to gravity, with time, so that the powder material adheres to the lower surface of the upper punch. The body material can be applied uniformly.
また、 空気に混和した粉# ^料を、 回転テーブルの回転方向と逆方向に流す構 成にしたので、 空気に混和した粉# ^料を、 回転テーブルの回転方向と順方向に 流した構成にしたものに比べ、 上杵 0下面へ、 粉体材料を効率良く衝突させるこ とができる。 In addition, the configuration is such that the powder mixed with air flows in the direction opposite to the direction of rotation of the rotary table, so that the powder mixed with air flows in the direction of rotation of the rotary table in the forward direction. The powder material can be made to efficiently collide with the lower surface of the upper punch 0 as compared with the above-described configuration.
これにより、 この粉体材料の塗布装置では、 効率良く、 上杵の下面へ、 粉体材 料を効率良く、 均一に、 塗布できる。 As a result, the powder material applying apparatus can efficiently and uniformly apply the powder material to the lower surface of the upper punch.
この粉体材料の塗布装置を用いれば、 その下面に、 万遍なく、 粉体材料が塗布 された上杵と、 その上面に、 万遍なく、 粉体材料が塗布された下杵と、 その内周 壁面に、 万遍なく、 粉体材料が塗布された曰とを用いて錠剤を製造できる。 If this powder material application device is used, an upper punch with the powder material uniformly applied to the lower surface thereof, and a lower punch with the powder material uniformly applied to the upper surface thereof, Tablets can be manufactured using the fact that the powder material is uniformly applied to the inner peripheral wall surface.
これにより、 粉体材料として、 滑沢剤を用いた場合には、 杵ゃ日に、 ギシヅキ を生じることなく、 且つ、 打錠障害 (ラミネ一ティング、 キヤヅビング、 スティ ッキング等) を生じることなく、 連続打錠が可能になる。 これにより、 生産べ一 スで、 外部滑沢錠剤の製造が可能になる。 As a result, when a lubricant is used as a powder material, no squeak and no tableting trouble (laminating, caving, sticking, etc.) occur on the punching day. Continuous tableting becomes possible. This makes it possible to manufacture external lubricating tablets on a production basis.
また、 この粉体材料の塗布装置を用いれば、 粉体材料として、 表面改質剤を用 いた場合には、 杵ゃ曰に、 表面改質剤を均一に塗布できるので、 錠剤の表面に表 面改質剤が均一に塗布された錠剤を生産効率良く製造できるようになる。 請求項 2 4に記載の粉体材料の塗布装置は、 請求項 2 3に記載の粉体材料の塗 布装置が、 上杵用の粉体材料の塗布装置のスリット部の上方に第 1の吸引手段を、 更に備え、 第 1の吸引手段は、 スリット部の領域を覆う大きさの吸引口を有して In addition, if a surface modifier is used as the powder material by using this powder material coating device, Kizuki says that the surface modifier can be applied uniformly, so that it can be displayed on the tablet surface. A tablet to which the surface modifier is uniformly applied can be manufactured with high production efficiency. In the powder material applying apparatus according to claim 24, the powder material applying apparatus according to claim 23 is arranged such that the powder material applying apparatus according to claim 23 is located above the slit portion of the powder material applying apparatus for the upper punch. Further comprising a suction means, wherein the first suction means has a suction port large enough to cover an area of the slit portion.
ヽ. ヽ.
おり、 且つ、 吸引口は、 平面視した場合、 複数の上杵の回転軌道の外周側に沿つ た形状をしており、 第 1の吸引手段を駆動すれば、 吸引口の形状により、 スリツ ト部の上方に、 スリット部から吸引口へ向かう気流が発生し、 スリット部に万遍 なく、 空気に分散された粉体材料が供給されるようになつている。 In addition, when viewed in a plan view, the suction port has a shape along the outer peripheral side of the rotation trajectory of the plurality of upper punches. When the first suction means is driven, the slit is formed by the shape of the suction port. An air current is generated from the slit to the suction port above the slit, and the powder material dispersed in the air is supplied to the slit uniformly.
この粉体材料の塗布装置では、 この粉体材料の塗布装置を構成する上杵用の粉 体材料の塗布装置のスリット部の上方に、 請求項 8に記載の上杵用の粉体材料の 塗布装置と同様の構成を備える第 1の吸引手段を設けているので、 請求項 8に記 載の上杵用の粉体材料の塗布装置と同様の効果を奏する。 The powder material application device for an upper punch according to claim 8, wherein the powder material application device includes an upper punch material application device that constitutes the powder material application device. Since the first suction means having the same configuration as that of the coating device is provided, the same effect as that of the powder material coating device for the upper punch described in claim 8 can be obtained.
請求項 2 5に記載の粉体材料の塗布装置は、 請求項 2 3又は請求項 2 4に記載 の粉体材料の塗布装置の、 上杵用の粉体材料の塗布装置のスリツ卜部の幅が、 錠 剤に形成する割線や刻印の領域の幅に概ね一致するようにされている。 The powder material application device according to claim 25 is the width of the slit portion of the powder material application device for the upper punch of the powder material application device according to claim 23 or 24. However, the width of the area of the score and the area of the stamp formed on the tablet are made to substantially match.
この粉体材料の塗布装置では、 この粉体材料の塗布装置を構成する上杵用の粉 体材料の塗布装置のスリット部の幅を、 請求項 1 3に記載の上杵用の粉体材料の 塗布装置と同様、 錠剤に形成する割線や刻印の領域の幅に概ね一致するようにし ているので、 請求項 1 3に記載の上杵用の粉体材料の塗布装置と同様の効果を奏 する。 The powder material application device for an upper punch according to claim 13, wherein the width of the slit portion of the powder material application device for the upper punch constituting the powder material application device is set in the powder material application device. Similar to the applicator of the first aspect, the width of the area of the dividing line or the mark formed on the tablet is made to substantially coincide with the width of the area. I do.
請求項 2 6に記載の粉体材料の塗布装置は、 請求項 2 3〜2 5のいずれかに記 載の上杵用の粉体材料の塗布装置の、 上杵用の粉体材料の塗布装置のスリット部 の形状が、 ジグザグ形状にされている。 The powder material applying device according to claim 26 is the powder material applying device for an upper punch of the powder material applying device for an upper punch according to any one of claims 23 to 25. The shape of the slit part of the device is zigzag.
この粉体材料の塗布装置では、 この粉体材料の塗布装置を構成する上杵用の粉 体材料の塗布装置のスリット部の形状を、 請求項 1 4に記載の上杵用の粉体材料 の塗布装置と同様、 ジグザグ形状にしているので、 請求項 1 4に記載の上杵用の 粉体材料の塗布装置と同様の効果を奏する。 15. The powder material applying device for an upper punch according to claim 14, wherein the shape of the slit portion of the powder material applying device for the upper punch constituting the powder material applying device is the same as that of the powder material applying device. Since it has a zigzag shape as in the case of the application device of the first aspect, the same effect as that of the powder material application device for an upper punch according to claim 14 is achieved.
請求項 2 7に記載の粉体材料の塗布装置は、 請求項 2 3〜2 6のいずれかに記 載の上杵用の粉体材料の塗布装置の、 上杵用の粉体材料の塗布装置のスリット部 の上方に、 所定の孔径を有するメッシュ手段を設けた。 この粉体材料の塗布装置では、 この粉体材料の塗布装置を構成する上杵用の粉 体材料の塗布装置のスリット部の上方に、 請求項 1 5に記載の上杵用の粉体材料 の塗布装置と同様、 所定の孔径を有するメッシュ手段を設けているので、 請求項The powder material applying device according to claim 27 is the powder material applying device for an upper punch of the powder material applying device for an upper punch according to any one of claims 23 to 26. Mesh means having a predetermined hole diameter was provided above the slit portion of the apparatus. 16. The powder material for an upper punch according to claim 15, wherein the powder material application device is provided above a slit portion of the powder material application device for an upper punch constituting the powder material application device. Similar to the coating device of the above, a mesh means having a predetermined hole diameter is provided.
1 5に記載の上杵用の粉体材料の塗布装置と同様の効果を奏する。 The same effects as those of the powder material application device for upper punches described in 15 are achieved.
請求項 2 8に記載の粉体材料の塗布装置は、 請求項 2 3〜 2 7のいずれかに記 載の粉体材料の塗布装置の、 下杵用の粉体材料の塗布装置の排出口が、 排出口の 真下に位置する曰内に所定の位置まで挿入されている下杵の上面の概ね中心部に、 概ね垂直方向を向くように設けられている。 A powder material applying device according to claim 28 is a discharge port of a powder material applying device for a lower punch of the powder material applying device according to any one of claims 23 to 27. Is provided at a substantially central portion of the upper surface of the lower punch, which is inserted to a predetermined position in a position located immediately below the discharge port, so as to face a substantially vertical direction.
この粉体材料の塗布装置は、 この粉体材料の塗布装置を構成する下杵用の粉体 材料の塗布装置の排出口を、 請求項 1 8に記載の下杵用の粉体材料の塗布装置の 排出口と同様、 排出口の真下に位置する曰内に所定の位置まで挿入されている下 杵の上面の概ね中心部に、 概ね垂直方向を向くように設けているので、 請求項 1 8に記載の下杵用の粉体材料の塗布装置と同様の効果を奏する。 The powder material application device for a lower punch according to claim 18, wherein an outlet of the powder material application device for a lower punch constituting the powder material application device is provided. Similar to the outlet of the device, the lower punch is inserted to a predetermined position in a position located immediately below the outlet, and is provided substantially in the center of the upper surface of the lower punch so as to be directed substantially vertically. The same effect as that of the powder material application device for lower punches described in 8 can be obtained.
請求項 2 9に記載の粉体材料の塗布装置は、 請求項 2 3 ~ 2 8のいずれかに記 載の粉体材料の塗布装置の、 下杵用の粉体材料の塗布装置の、 回転テーブルの回 転方向側に、 貫通孔の排出口から、 本体に収容される、 下杵及び臼に吹き付けら れ、 下杵及び曰に余分に付着している粉体材料、 及び回転テーブル上の余分な粉 体材料を除去する第 2の吸引手段が、 更に、 設けられている。 A powder material applying device according to claim 29 is a rotary member of a powder material applying device for a lower punch, wherein the powder material applying device according to any one of claims 23 to 28 is a rotating device. On the rotating direction side of the table, through the outlet of the through hole, the lower punch and the powder material that are sprayed onto the lower punch and die, which are housed in the main body, A second suction means for removing excess powder material is further provided.
この粉体材料の塗布装置では、 この粉体材料の塗布装置を構成する下杵用の粉 体材料の塗布装置に、 請求項 1 9に記載の下杵用の粉体材料の塗布装置と同様の 構成を有する第 2の吸引手段を更に設けているので、 請求項 1 9に記載の下杵用 の粉体材料の塗布装置と同様の効果を奏する。 In the powder material coating apparatus, the lower punch material powder coating apparatus constituting the powder material coating apparatus is similar to the lower punch powder material coating apparatus according to claim 19. Since the second suction means having the above configuration is further provided, the same effect as that of the powder material applying apparatus for lower punches according to claim 19 can be obtained.
請求項 3 0に記載の粉体材料の塗布装置は、 請求項 2 9に記載の粉体材料の塗 布装置の、 第 2の吸引手段は、 回転テーブルに設けられる、 複数の臼の回転軌道 に直交するように、 複数の臼の各々及びそれらの周辺をカバーできる長さのスリ ット状の吸引口を有している。 The apparatus for applying a powder material according to claim 30 is the apparatus for applying a powder material according to claim 29, wherein the second suction means is provided on a rotary table. It has a slit-shaped suction port long enough to cover each of the plurality of dies and the periphery thereof so as to be orthogonal to.
この粉体材料の塗布装置では、 この粉体材料の塗布装置を構成する下杵用の粉 体材料の塗布装置に設ける第 2の吸引手段の吸引口を、 請求項 2 0に記載の下杵 用の粉体材料の塗布装置と同様の構成にしているので、 請求項 2 0に記載の下杵 用の粉体材料の塗布装置と同様の効果を奏する。 The lower punch according to claim 20, wherein the powder material application device includes a suction port of a second suction unit provided in the powder material application device for the lower punch constituting the powder material application device. 20. The lower punch according to claim 20, which has a configuration similar to that of the powder material application device for The same effect as that of the powder material coating device for use can be obtained.
請求項 3 1に記載の粉体材料の塗布装置は、 請求項 3 0に記載の粉体材料の塗 布装置の、 第 2の吸引手段の吸引口は、 少なくとも、 前記排出口が設けられてい る位置から、 前記回転テーブルに設けられる、 複数の曰の各々の直径より、 離れ た位置に設けられている。 In the powder material coating apparatus according to claim 31, the suction port of the second suction means of the powder material coating apparatus according to claim 30 is provided with at least the discharge port. A plurality of said diameters provided on the rotary table from a position at which the rotary table is located.
この粉体材料の塗布装置では、 下杵の上面及び曰の内周壁面に塗布された粉体 材料の中、 下杵の上面及び臼の内周壁面にとって余分な粉体材料を、 臼内に所定 の位置まで挿入された下杵の上面に、 空気脈動波の気流に分散した粉体材料を直 接吹き付ける場所とは、 導通しない場所で、 吸引除去するようにしているので、 曰内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分散した粉 体材料を直接吹き付ける条件に影響を与えることなく、 下杵の上面及び曰の内周 壁面に塗布された粉体材料の中、 下杵の上面及び臼の内周壁面にとって余分な粉 体材料を、 吸引除去することができる。 In this powder material application device, the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface of the die, of the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface, is put into the die. The place where the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface of the lower punch inserted to the predetermined position is a place where it does not conduct, and it is suctioned and removed. The powder applied to the upper surface of the lower punch and the inner wall of the lower punch without affecting the conditions for directly blowing the powder material dispersed in the air current of the air pulsating wave onto the upper surface of the lower punch inserted up to the position Excess powder material in the upper surface of the lower punch and the inner peripheral wall of the die can be removed by suction.
請求項 3 2に記載の粉体材料の塗布装置は、 請求項 2 3〜 3 1のいずれかに記 載の下杵用の粉体材料の塗布装置の、'下杵用の粉体材料の塗布装置の回転テープ ルに対向する表面の、 排出口の前段部に、 更に、 複数の下杵の上面、 複数の曰内 及び複数の曰の周辺に付着している成形材料を、 順次、 除去するために設けられ、 複数の臼の回転軌道に概ね直交するような成形材料吸引口を有する第 3の吸引手 段を設けた。 The powder material coating apparatus according to claim 32 is the powder material coating apparatus for lower punches according to any one of claims 23 to 31. The molding material adhering to the front surface of the discharge port on the surface facing the rotating tape of the coating device, and further to the upper surface of the lower punches, the inner walls and the outer periphery, is sequentially removed. And a third suction means provided with a molding material suction port that is substantially orthogonal to the rotation orbits of the plurality of dies.
この粉体材料の塗布装置では、 この粉体材料の塗布装置を構成する下杵用の粉 体材料の塗布装置に、 請求項 2 2に記載の下杵用の粉体材料の塗布装置と同様の 第 3の吸引手段を設けているので、 請求項 2 2に記載の下杵用の粉体材料の塗布 装置と同様の効果を奏する。 In this powder material coating apparatus, the powder material coating apparatus for lower punches constituting the powder material coating apparatus is the same as the powder material coating apparatus for lower punches according to claim 22. Since the third suction means is provided, the same effect as the powder material application device for lower punches according to claim 22 can be obtained.
請求項 3 3に記載の粉体材料の塗布装置は、 請求項 2 3〜 3 2のいずれかに記 載の粉体材料の塗布装置の、 上杵用の粉体材料の塗布装置のスリツト部の代わり に、 上杵収容溝の底面に、 複数の上杵の回転軌道に沿って、 上杵収容溝内を移動 する複数の上杵の下面に、 空気脈動波の気流に分散された粉体材料を噴霧する、 複数の噴射孔を配置した。 The powder material application device according to claim 33 is a slit portion of the powder material application device for an upper punch of the powder material application device according to any one of claims 23 to 32. Instead, on the bottom surface of the upper punch receiving groove, on the lower surface of multiple upper punches moving in the upper punch receiving groove along the rotation path of the multiple upper punches, the powder dispersed in the air current of the air pulsating wave A plurality of injection holes for spraying the material were arranged.
この粉体材料の塗布装置では、 上杵用の粉体材料の塗布装置のスリツト部の代 わりに、 上杵収容溝の底面に、 複数の上杵の回転軌道に沿って、 上杵収容溝内を 移動する複数の上杵の下面に、 空気脈動波の気流に分散された粉体材料を噴霧す る、 複数の噴射孔を配置したので、 粉体材料が、 複数の噴射孔の各々から噴霧さIn this powder material coating device, the slit portion of the powder material coating device for the upper punch is replaced. Instead, on the bottom surface of the upper punch receiving groove, the powder material dispersed in the air current of the air pulsating wave is Because of the arrangement of multiple spray holes, the powder material is sprayed from each of the multiple spray holes.
、- れる際に、 気流に、 ある種の整流効果が得られる。 In the process, a certain rectifying effect is obtained in the airflow.
これにより、 重力との関係で、 粉体材料が付着し難い、 上杵の下面に、 粉体材 料が、 均一に塗布される。 As a result, the powder material hardly adheres due to the gravity, and the powder material is uniformly applied to the lower surface of the upper punch.
請求項 3 4に記載の粉体材料の塗布装置は、 請求項 2 3〜 3 3のいずれかに記 載の粉体材料の塗布装置の、 下杵用の粉体材料の塗布装置に、 回転テーブルの回 転方向と逆方向ではなく、 順方向の位置に、 上杵用の粉体材料の塗布装置部が接 続されている。 The powder material applying apparatus according to claim 34 is a rotary apparatus for the powder material applying apparatus for lower punches of the powder material applying apparatus according to any one of claims 23 to 33. An application unit for the powder material for the upper punch is connected at a position in the forward direction, not in the direction opposite to the rotation direction of the table.
この粉 料の塗布装置では、 この粉体材料の塗布装置を構成する下杵用の粉 体材料の塗布装置に、 回転テーブルの回転方向と順方向の位置に、 上杵用の粉体 材料の塗布装置を接続しているので、 回転テーブルの回転方向と下杵用の粉^ 料の塗布装置から上杵用の粉体材料の塗布装置へと供給される、 空気に混和した 粉体材料の流れの向きが同方向になるので、 少ない抵抗で、 静かな状態 (負圧雰 囲気下) で、 上杵の下面に、 粉体材料を塗布できる。 In this powder coating device, the powder material coating device for the lower punch, which constitutes the powder material coating device, is provided with the powder material for the upper punch at a position in the rotation direction and the forward direction of the rotary table. Since the coating device is connected, the rotating direction of the rotary table and the powder material for the lower punch are supplied from the powder coating device for the upper punch to the powder material coating device for the upper punch. Since the flow direction is the same, the powder material can be applied to the lower surface of the upper punch with low resistance and in a quiet state (under a negative pressure atmosphere).
請求項 3 5は、 外部滑沢式打錠機について規定する。 Claim 35 specifies an external lubricating tablet press.
即ち、 請求項 3 5に記載の外部滑沢式打錠機は、 連続打錠機の、 複数の日が周 方向に設けられた回転テーブル上の所定の位置に、 回転テーブルが回転可能なよ うに、 請求項 1 1〜3 4のいずれかに記載の粉体材料の塗布装置を固定的に取り 付けた。 That is, in the external lubricating tablet press according to claim 35, the rotary table can be rotated at a predetermined position on a rotary table provided with a plurality of days in a circumferential direction of the continuous tablet press. As described above, the powder material application device according to any one of claims 11 to 34 is fixedly attached.
この外部滑沢式打錠機では、 例えば、 従来のロータリ型打錠機等打錠機の所定 の位置 (滑沢剤噴霧ポイント) に、 請求項 1 1〜3 4のいずれかに記載の粉体材 料の塗布装置を固定的に取り付けるという簡単な作業で、 粉体材料として、 滑沢 剤を用いた場合には、 杵ゃ曰に、 ギシヅキを生じることなく、 且つ、 打錠障害 In this external lubricating tablet press, for example, the powder according to any one of claims 11 to 34 is provided at a predetermined position (lubricant spray point) of a conventional tablet press such as a rotary tablet press. In the simple work of fixedly attaching the body material application device, if a lubricant is used as the powder material, the punch does not produce a squeak and a tableting failure.
(ラミネ一ティング、 キヤッビング、 スティヅキング等) を生じることなく、 連 続打錠が可能になり、 これにより、 生産ペースで、 外部滑沢錠剤の製造が可能な になる、 外部滑沢式打錠機を市場に提供することができる。 (Tableting, laminating, cabbing, sticking, etc.) without the need for continuous tableting, making it possible to manufacture external lubricating tablets at a production pace. Can be provided to the market.
また、 粉 料として、 表面改質剤を用いた場合には、 杵ゃ臼に、 表面改質剤 を均一に塗布できるので、 この外部滑沢式打錠機を用いれば、 表面改質剤が均一 に塗布された杵と とを用いて、 錠剤を製造できるので、 錠剤の表面に表面改質 剤が均一に塗布された錠剤を製造できる、 外部滑沢式打淀機を市場に提供するこ When a surface modifier is used as the powder, the surface modifier is The tablet can be manufactured using this external lubricating tableting machine using a punch and a surface to which the surface modifier has been evenly applied, so that the surface modifier can be applied to the surface of the tablet. To provide tablets with an external lubricated punching machine capable of producing tablets with uniform coating.
、- とができるようになる。 図面の簡単な説明 ,-And can be. BRIEF DESCRIPTION OF THE FIGURES
図 1は、 本発明に係る外部滑沢式打錠機の一例を概略的に示す全体構成図であ る。 FIG. 1 is an overall configuration diagram schematically showing an example of an external lubricating tableting machine according to the present invention.
図 2は、 図 1に示す外部滑沢式打錠機を構成する口一夕リ型打錠機の回転テー ブル、 上杵用の粉体材料の塗布装置及び下杵用の粉体材料の塗布装置の配置を概 略的に示す平面図である。 Fig. 2 shows the rotary table of the open-type tableting machine that constitutes the external lubricating tableting machine shown in Fig. 1, the coating device for the powder material for the upper punch, and the powder material for the lower punch. FIG. 3 is a plan view schematically showing an arrangement of a coating device.
図 3は、 図 2に示す回転テーブルを、 成形材料充填ボイントと滑沢剤塗布ボイ ントとの間で切断して展開した模式的な展開図である。 FIG. 3 is a schematic developed view in which the rotary table shown in FIG. 2 is cut and developed between a molding material filling point and a lubricant applying point.
図 4は、 上杵用の粉体材料の塗布装置を概略的に示す図であり、 図 4 (a)は、 上杵用の粉体材料の塗布装置を、 図 2中、 I一 I線方向に見た斜視図を、 図 4 (b) は、 図 4 (a) 中、 IV— IV線に従う概略的な断面図であり、 上杵用の 粉体材料の塗布装置の近傍に設けられる吸引ダクトがともに示されている。 FIG. 4 is a diagram schematically showing a powder material application device for the upper punch, and FIG. 4 (a) is a powder material application device for the upper punch. Fig. 4 (b) is a schematic cross-sectional view taken along the line IV-IV in Fig. 4 (a), which is provided in the vicinity of the powder material application device for the upper punch. The suction duct is shown together.
図 5は、 吸引ダクトの吸引口を中心にして、 その形状を概略的に示す斜視図で ある。 FIG. 5 is a perspective view schematically showing the shape of the suction duct centered on the suction port.
図 6は、 下杵用の粉体材料の塗布装置を概略的に説明する図であり、 図 6 (a) は、 図 2中、 I I— I I線方向に見た斜視図を、 図 6 (b)は、 図 6 (a) 中、 VI— VI線に従う概略的な断面図であり、 また、 図 6 (c) は、 図 6 (b) に 示した状態から一定時間が経過した状態を概略的に示す断面図である。 FIG. 6 is a diagram schematically illustrating a powder material application device for a lower punch. FIG. 6 (a) is a perspective view taken along line II-II in FIG. FIG. 6 (b) is a schematic cross-sectional view taken along the line VI-VI in FIG. 6 (a), and FIG. 6 (c) is a state in which a certain time has elapsed from the state shown in FIG. 6 (b). It is sectional drawing which shows schematically.
図 7は、 図 1中、 VI I部分を更に拡大して概略的に示す断面図である。 FIG. 7 is a cross-sectional view schematically showing a VII portion in FIG. 1 in a further enlarged manner.
図 8は、 弾性膜体を概略的に示す平面図である。 FIG. 8 is a plan view schematically showing an elastic film body.
図 9は、 分散室を平面視した場合の、 分散室に設ける空気脈動波導入口の位置 を模式的に示す平面図であり、 図 9 (a) は、 空気脈動波導入口の理想的な取付 け位置を説明する図であり、 また、 図 9 (b) は、 空気脈動波導入口 55 aの実 質的に可能な取付け位置を説明する図である。 図 1 0は、 分散室を平面視した場合の、 分散室に設ける空気脈動波導入口と排 出口との位置関係を模式的に説明する図であり、 図 1 0 ( a ) は、 空気脈動波導 入口と排出口との実質的に可能な位置関係を説明する図であり、 また、 図 1 0Fig. 9 is a plan view schematically showing the position of the air pulsation wave introduction port provided in the dispersion chamber when the dispersion chamber is viewed in plan.Fig. 9 (a) shows the ideal installation of the air pulsation wave introduction port. FIG. 9B is a view for explaining the position, and FIG. 9B is a view for explaining a practically possible mounting position of the air pulsation wave introduction port 55a. Fig. 10 is a diagram schematically illustrating the positional relationship between the air pulsation wave introduction port and the discharge outlet provided in the dispersion chamber when the dispersion chamber is viewed in a plan view, and Fig. 10 (a) shows the air pulsation wave conduction. FIG. 10 is a view for explaining a substantially possible positional relationship between an inlet and an outlet, and FIG.
、' , '
( b ) は、 空気脈動波導入口と排出口との好ましい位置関係を説明する図である。 図 1 1は、 分散室内に、 空気脈動波を送り込んだ際に、 弾性膜体に生じる現象 を模式的に説明する説明図である。 (b) is a diagram illustrating a preferred positional relationship between the air pulsation wave inlet and the outlet. FIG. 11 is an explanatory diagram schematically illustrating a phenomenon that occurs in the elastic film when an air pulsation wave is sent into the dispersion chamber.
図 1 2は、 本発明に好適な空気脈動波発生装置を概略的に示す断面図である。 図 1 3は、 本発明に係る下杵用の粉体材料の塗布装置の他の例を概略的に示す 平面図である。 FIG. 12 is a cross-sectional view schematically showing an air pulsation wave generator suitable for the present invention. FIG. 13 is a plan view schematically showing another example of a powder material applying device for a lower punch according to the present invention.
図 1 4は、 本発明に係る外部滑沢式打錠機の他の一例を概略的に示す全体構成 図である。 FIG. 14 is an overall configuration diagram schematically showing another example of the external lubricating tableting machine according to the present invention.
図 1 5は、 図 1 4に示す外部滑沢式打錠機を構成するロータリ型打錠機の回転 テーブル、 上杵用の粉体材料の塗布装置及び下杵用の粉体材料の塗布装置の配置 を概略的に示す平面図である。 Fig. 15 shows the rotary table of the rotary tableting machine that constitutes the external lubricating tablet press shown in Fig. 14, a powder material coating device for the upper punch and a powder material coating device for the lower punch. FIG. 4 is a plan view schematically showing the arrangement of the components.
図 1 6は、 図 1 5に示す回転テーブルを、 成形材料充填ボイントと滑沢剤塗布 ポイントとの間で切断して展開した模式的な展開図を示している。 FIG. 16 is a schematic developed view in which the rotary table shown in FIG. 15 is cut and developed between a molding material filling point and a lubricant application point.
図 1 7は、 本発明に係る粉体材料の塗布装置を備える外部滑沢式打錠機の一例 を概略的に示す全体構成図である。 FIG. 17 is an overall configuration diagram schematically showing an example of an external lubricating tableting machine provided with the powder material application device according to the present invention.
図 1 8は、 図 1 7に示す外部滑沢式打錠機を構成するロータリ型打錠機の回転 テーブル、 粉体材料の塗布装置の配置を概略的に示す平面図である。 FIG. 18 is a plan view schematically showing an arrangement of a rotary table and a powder material coating device of the rotary tableting machine constituting the external lubricating tableting machine shown in FIG.
図 1 9は、 図 1 7に示す回転テーブルを、 成形材料充填ボイントと滑沢剤塗布 ポイントとの間で切断して展開した模式的な展開図を示している。 FIG. 19 is a schematic developed view in which the rotary table shown in FIG. 17 is cut and developed between the molding material filling point and the lubricant application point.
図 2 0は、 この粉体材料の塗布装置を概略的に示す平面図である。 FIG. 20 is a plan view schematically showing an apparatus for applying the powder material.
図 2 1は、 図 2 0中、 XX I— XX I線に従う概略的な断面図である。 FIG. 21 is a schematic sectional view taken along the line XXI—XXI in FIG.
図 2 2は、 図 2 1中、 XX I I— XX I I線に従う概略的な断面図である。 図 2 3は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す平面図 である o FIG. 22 is a schematic sectional view taken along the line XXII-XXII in FIG. FIG. 23 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
図 2 4は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す平面図 である。 図 2 5は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す平面図 である。 FIG. 24 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention. FIG. 25 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
図 2 6は、 図 2 5中、 XXV I—XXV I線に従う概略的な断面図である。 FIG. 26 is a schematic sectional view taken along the line XXVI-XXVI in FIG.
ヽ- 図 2 7は、 本発明に係る粉体材料め塗布装置の他の一例を概略的に示す平面図 である。 Fig. 27 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
図 2 8は、 図 2 7中、 XXV I I I— XXV I I I線に従う概略的な断面図で める。 FIG. 28 is a schematic cross-sectional view along the line XXVIII—XXVIII in FIG.
図 2 9は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す平面図 である。 FIG. 29 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
図 3 0は、 図 2 9中、 XXX— XXX線に従う概略的な断面図である。 FIG. 30 is a schematic sectional view taken along line XXX-XXX in FIG.
図 3 1は、 本発明に係る外部滑沢式打錠機で用いた、 粉体材料の吐出装置の、 噴霧量と経過時間との相関関係を示す折れ線グラフである。 FIG. 31 is a line graph showing the correlation between the spray amount and the elapsed time of the powder material discharging device used in the external lubricating tableting machine according to the present invention.
図 3 2は、 本発明に係る外部滑沢式打錠機で用いた、 粉体材料の吐出装置では、 粉体材料貯留室内に貯留する粉体材料の量が噴霧量に影響することを示す、 噴霧 量と経過時間との相関関係を示す折れ線グラフである。 FIG. 32 shows that in the powder material discharging device used in the external lubricating tablet press according to the present invention, the amount of the powder material stored in the powder material storage chamber affects the spray amount. 4 is a line graph showing a correlation between a spray amount and an elapsed time.
図 3 3は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す平面図 である。 FIG. 33 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
図 3 4は、 特閧昭 5 6 - 1 4 0 9 8号公報に記載の従来の外部滑沢式打錠機を 用いて錠剤を製造する方法を概略的に示す工程図である。 FIG. 34 is a process chart schematically showing a method for producing a tablet using a conventional external lubricating tableting machine described in Japanese Patent Publication No. 56-14098.
図 3 5は、 特閧平 7— 1 2 4 2 3 1号公報に記載の、 本発明者等が既に提案し ている、 従来の外部滑沢式打錠機の要部を概略的に示す構成図である。 Fig. 35 schematically shows a main part of a conventional external lubricating tableting machine described in Japanese Patent Application Laid-Open No. 7-124234 and already proposed by the present inventors. It is a block diagram.
図 3 6は、 空気脈動波を概略的に示す図であり、 図 3 6 ( a) は、 山が正圧で、 谷が大気圧の空気脈動波を、 又、 図 3 6 ( b ) は、 山と谷とがともに正圧の空気 脈動波を、 各々、 例示的に示している。 発明を実施するための最良の形態 FIG. 36 is a diagram schematically showing an air pulsation wave, and FIG. 36 (a) shows an air pulsation wave in which a mountain has a positive pressure and a valley has an atmospheric pressure, and FIG. Each of the peaks and the valleys exemplifies a positive pressure air pulsation wave. BEST MODE FOR CARRYING OUT THE INVENTION
以下、 本発明について、 図面を参照しながら更に詳しく説明する。 Hereinafter, the present invention will be described in more detail with reference to the drawings.
尚、 以下の説明では、 粉体材料として、 滑沢剤粉末を用いた場合を中心に説明 する。 (発明の実施の形態 1 ) In the following description, the case where a lubricant powder is used as the powder material will be mainly described. (Embodiment 1)
発明の実施の形態 1では、 上杵用の粉体材料の塗布装置と、 下杵用の粉体材料 の塗布装置とを別体に設け、 且つ、 これらを、 打錠機の回転テ一ブルの別の位置 に設けた例について説明する。 In the first embodiment of the present invention, a powder material application device for an upper punch and a powder material application device for a lower punch are separately provided, and these are provided on a rotary table of a tableting machine. An example provided at another position will be described.
図 1は、 本発明に係る外部滑沢式打錠機の一例を概略的に示す全体構成図であ る。 FIG. 1 is an overall configuration diagram schematically showing an example of an external lubricating tableting machine according to the present invention.
この外部滑沢式打錠機 1は、 ロータリ型打錠機 2と、 上杵用の粉体材料の塗布 装置 3と、 下杵用の粉体材料の塗布装置 4と、 上杵用の粉体材料の塗布装置 3及 び下杵用の粉体材料の塗布装置 4の各々に、 粉体材料を供給する、 粉体材料の吐 出装置 (定量フィーダ) 5と、 ブロア等の空気源 7と、 空気源 7を駆動すること により発生させた圧縮空気を、 正圧の空気脈動波に変換する空気脈動波発生装置 8とを備える。 The external lubricating tableting machine 1 is composed of a rotary tableting machine 2, a powder material coating device 3 for an upper punch, a powder material coating device 4 for a lower punch, and a powder material for an upper punch. A powder material discharge device (quantitative feeder) 5 that supplies the powder material to each of the body material coating device 3 and the powder material coating device 4 for the lower punch, and an air source 7 such as a blower And an air pulsation wave generator 8 that converts compressed air generated by driving the air source 7 into a positive pressure air pulsation wave.
尚、 図 1中、 1 0で示す部材装置 ίま、 この外部滑沢式打錠機 1全体の動作環境 を制御する演算装置を、 また、 1 1で示す部材装置は、 ブロア等の第 1の吸引手 段を示している。 In FIG. 1, a member device denoted by reference numeral 10 denotes a computing device for controlling the entire operating environment of the external lubricating tableting machine 1. A member device denoted by reference numeral 11 denotes a first device such as a blower. This shows the suction means.
また、 T 1で示す部材は、 空気源 7と空気脈動波発生装置 8とを接続する配管 を、 Τ 2で示す部材は、 空気脈動波発生装置 8と粉体材料の吐出装置 (定量フィ —ダ) 5とを接続する配管を、 また、 Τ 3で示す部材は、 粉体材料の吐出装置 (定量フィーダ) 5と、 上杵用の粉体材料の塗布装置 3及び下杵用の粉体材料の 塗布装置 4の各々とを接続する配管 ¾、 各々、 示している。 また、 Τ 4で示す部 材は、 第 1の吸引手段 1 1に接続された吸引ダクトを示している。 The member indicated by T1 is a pipe connecting the air source 7 and the air pulsation wave generator 8, and the member indicated by Τ2 is an air pulsation wave generator 8 and a powder material discharge device (quantitative filter). The pipes that connect to 5) and the members indicated by Τ3 are the powder material discharge device (quantitative feeder) 5, the powder material application device 3 for the upper punch, and the powder for the lower punch. Pipes connecting each of the material coating devices 4 are shown. In addition, the member indicated by reference numeral 4 indicates a suction duct connected to the first suction means 11.
配管 T 1の途中には、 流量制御装置 1 2が接続されており、 流量制御装置 1 2 により、 空気源 7を駆動することにより発生させた圧縮空気の流量を調整できる ようにしている。 A flow control device 12 is connected in the middle of the pipe T1 so that the flow control device 12 can adjust the flow rate of the compressed air generated by driving the air source 7.
また、 配管 Τ 3は、 粉体材料の吐出装置 (定量フィーダ) 5からは、 1本の管 として導出され、 途中で、 2本の配管 T 3 a、 T 3 bに分岐し、 配管 T 3 aが、 上杵用の粉体材料の塗布装置 3に接続され、 また、 配管 T 3 が、 下杵用の粉体 材料の塗布装置 4に接続されている。 In addition, the pipe Τ3 is led out from the powder material discharge device (quantitative feeder) 5 as one pipe, and branches along the way into two pipes T3a and T3b to form a pipe T3. a is connected to the powder material coating device 3 for the upper punch, and the pipe T 3 is connected to the powder material coating device 4 for the lower punch.
そして、 2本の配管 T 3 a、 T 3 bの各々には、 電磁弁等の流量制御弁 v 1、 v 2が各々設けられている。 Each of the two pipes T 3a and T 3b has a flow control valve v 1 such as a solenoid valve, v 2 is provided for each.
また、 吸引ダクト T 4の途中には、 電磁弁等の流量制御弁 V 3が設けられてい る o 、' In the middle of the suction duct T4, a flow control valve V3 such as a solenoid valve is provided.
また、 C 1で示す部材は、 演算装置 1 0と、 流量制御装置 1 2及び空気脈動波 発生装置 8の各々との間で信号をやりとりする信号線を示しており、 流量制御装 置 1 2及び空気脈動波発生装置 8の各々は、 演算装置 1 0の制御信号に基づいて 動作するようにされている。 Further, members indicated by C1 indicate signal lines for exchanging signals between the arithmetic unit 10 and each of the flow control device 12 and the air pulsation wave generator 8, and the flow control device 12 Each of the air pulsation wave generator 8 and the air pulsation wave generator 8 operates based on the control signal of the arithmetic unit 10.
また、 C 2は、 演算装置 1 0と流量制御弁 v lとの間で信号をやりとりする信 号線を示しており、 流量制御弁 v lは、 演算装置 1 0の制御信号に基づいて、 そ の開閉量を所定の開閉量に制御できるようになつている。 C 2 indicates a signal line for exchanging signals between the arithmetic unit 10 and the flow control valve vl. The flow control valve vl opens and closes based on the control signal of the arithmetic unit 10. The amount can be controlled to a predetermined opening / closing amount.
また、 C 3は、 演算装置 1 0と流量制御弁 v lとの間で信号をやりとりする信 号線を示しており、 流量制御弁 V 2は、 演算装置 1 0の制御信号に基づいて、 そ の開閉量を所定の開閉量に制御できるようになつている。 C 3 indicates a signal line for exchanging signals between the arithmetic unit 10 and the flow control valve vl, and the flow control valve V 2 controls the flow of the signal based on the control signal of the arithmetic unit 10. The opening / closing amount can be controlled to a predetermined opening / closing amount.
同様に、 C 4は、 演算装置 1 0と流量制御弁 V 3との間で信号をやりとりする 信号線を示しており、 流量制御弁 v 3は、 演算装置 1 0の制御信号に基づいて、 その開閉量を所定め開閉量に制御できるようになつている。 Similarly, C 4 indicates a signal line for exchanging signals between the arithmetic unit 10 and the flow control valve V 3, and the flow control valve v 3 is based on a control signal of the arithmetic unit 10, The opening / closing amount can be controlled to a predetermined opening / closing amount.
次に、 外部滑沢式打錠機 1を構成する、 口一タリ型打錠機 2、 上杵用の粉体材 料の塗布装置 3及び下杵用の粉体材料の塗布装置 4の構成について、 更に、 詳し く説明する。 Next, the configuration of the external lubricating tableting machine 1, the one-shot tableting machine 2, the powder material application device 3 for the upper punch and the powder material application device 4 for the lower punch Will be described in more detail.
図 2は、 外部滑沢式打錠機 1を構成する口一夕リ型打錠機 2の回転テーブル 2 1、 上杵用の粉体材料の塗布装置 3及び下杵用の粉体材料の塗布装置 4の配置を 概略的に示す平面図であり、 また、 図 3は、 図 2に示す回転テーブル 2 1を、 成 形材料充填ボイント P 2と滑沢剤塗布ボイント P 1との間で切断して展開した模 式的な展開図を示している。 Fig. 2 shows the rotary table 21 of the lip-type tableting machine 2 that constitutes the external lubricating tableting machine 1, the applicator 3 for the powder material for the upper punch, and the powder material for the lower punch. FIG. 3 is a plan view schematically showing an arrangement of a coating device 4, and FIG. 3 shows a rotary table 21 shown in FIG. 2 between a molding material filling point P 2 and a lubricant applying point P 1. A schematic development view cut and expanded is shown.
口一タリ型打錠機 2は、 複数の曰 2 2 · · *が周方向に設けられ且つ回転可能 に設けられた回転テーブル 2 1と、 回転テーブル 2 1の回転と同期して回転する ようにされた複数の上杵 2 3 · · ·と、 回転テーブル 2 1の回転と同期して回転 するようにされた複数の下杵 2 4 · · ·とを備える。 The one-shot tablet press 2 is provided with a plurality of rotary tables 21 provided in the circumferential direction and rotatably provided, and a rotary table 21 that rotates in synchronization with the rotation of the rotary table 21. , And a plurality of lower punches 24 that are rotated in synchronization with the rotation of the turntable 21.
尚、 この外部滑沢式打錠機 1では、 図 2及び図 3に図示するように、 新たに、 滑沢剤噴霧ボイント P 1を、 上杵用の滑沢剤噴霧ポイント P 1 aと、 下杵用の滑 沢剤噴霧ボイント P 1わの 2つに分けている。 In this external lubricating tablet press 1, as shown in FIGS. 2 and 3, The lubricant spray point P1 is divided into two parts, a lubricant spray point P1a for the upper punch and a lubricant spray point P1 for the lower punch.
そして、 上杵用の滑沢剤噴霧ボイント P 1 aに、 上杵用の粉体材料の塗布装置 3を設置し、 また、 下杵用の滑沢剤噴霧ポイント P l bには、 下杵用の粉体材料 の塗布装置 4を設置している点に特徴がある。 Then, a powder material application device 3 for the upper punch is installed at the lubricant spraying point P 1 a for the upper punch, and a lubricant spraying point P lb for the lower punch is used for the lower punch. It is characterized in that a powder material coating device 4 is installed.
下杵用の滑沢剤噴霧ポイント P l bでは、 下杵 2 4の上面 S 2 4は、 臼 2 2内 において、 最下位の位置となるようにされている。 At the lubricant spray point P lb for the lower punch, the upper surface S 24 of the lower punch 24 is located at the lowest position in the mill 22.
即ち、 下杵 2 4の上面 S 2 4が、 臼 2 2内で最下位となる位置で、 下杵 2 4の 上面 S 2 4及び曰 2 2の内周壁面 (臼 2 2の内周壁面の中、 下杵 2 4の上面 S 2 4より上方の内周壁面) S 2 2に、 粉体材料を塗布するようにし、 成形材料を圧 縮成形する際に、 成形材料に接触する臼 2 2の内周壁面 S 2 2に、 万遍なく、 粉 体材料を塗布するようにしているので、 臼 2 2に、 錠剤を製造する際に、 成形材 料が付着しない (この構成は、 以下に説明する発明の実施の形態 2においても同 様である。 ) 。 That is, at the position where the upper surface S 24 of the lower punch 24 is the lowest position in the mortar 22, the upper surface S 24 of the lower punch 24 and the inner peripheral wall surface of the lower die 22 (the inner peripheral wall surface of the mortar 22) The inner surface of the upper surface of the lower punch 24 above the inner surface of the lower punch 24) The powder material is applied to S22, and when the molding material is compression-molded, the die 2 that comes into contact with the molding material is pressed. Since the powder material is applied evenly to the inner peripheral wall S22 of No.2, the molding material does not adhere to the mortar 22 when manufacturing the tablet. The same applies to the second embodiment of the invention described below.
尚、 この例では、 上杵用の粉体材料の塗布装置 3は、 接続用プレート 3 O pを 備える。 この接続用プレート 3 O pは、 上杵用の粉体材料の塗布装置 3への配管 を容易とするために設けられるものであり、 回転テーブル 2 1より外方にはみ出 すように設けられ、 その上面に、 後述する接続口 e 8、 e 9が設けられている。 また、 下杵用の粉体材料の塗布装置 4は、 接続プレート 4 O pを備える。 この 接続用プレート 4 0 pは、 下杵用の粉体材料の塗布装置 4への配管を容易とする ために設けられるものであり、 回転テーブル 2 1より外方にはみ出すように設け られ、 その上面に、 後述する粉体材料導入口 e 1及び排出口 e 5が設けられてい o In this example, the powder material applying device 3 for the upper punch includes a connection plate 3 Op. The connection plate 3 Op is provided for facilitating the piping of the powder material for the upper punch to the coating device 3, and is provided so as to protrude outward from the turntable 21. On its upper surface, connection ports e8 and e9 described later are provided. Further, the powder material applying device 4 for the lower punch includes a connection plate 4 Op. The connection plate 40 p is provided for facilitating the piping of the powder material for the lower punch to the applicator 4, and is provided so as to protrude outward from the rotary table 21. On the upper surface, a powder material introduction port e1 and a discharge port e5 described later are provided.o
まず、 上杵用の粉体材料の塗布装置 3の構成について説明する。 First, the configuration of the powder material application device 3 for the upper punch will be described.
図 4は、 上杵用の粉体材料の塗布装置 3を概略的に示す図であり、 図 4 ( a ) は、 上杵用の粉体材料の塗布装置 3を、 図 2中、 I— I線方向に見た斜視図を、 図 4 ( b ) は、 図 4 ( a ) 中、 I V— I V線に従う概略的な断面図であり、 上杵 用の粉体材料の塗布装置 3の近傍に設けられる吸引ダクト T 4がともに示されて いる。 この上杵用の粉体材料の塗布装置 3は、 図 4 ( a ) に示すように、 複数の上杵 2 3 · · ·の回転軌道 (図 4 ( a ) 中に、 一点鎖線で示す回転軌道 O r ) の下方 に設けられている。 FIG. 4 is a view schematically showing a powder material application device 3 for the upper punch, and FIG. 4 (a) is a powder material application device 3 for the upper punch. Fig. 4 (b) is a schematic cross-sectional view taken along the line IV-IV in Fig. 4 (a). The suction duct T4 provided at the bottom is also shown. As shown in Fig. 4 (a), the powder material application device 3 for the upper punch uses a plurality of upper punches 2 3... It is located below the orbit (Or).
尚、 上杵用の粉体材料の塗布装置 3は、 複数の上杵 2 3 · ♦ ·の回転軌道 O r の下方に設けられている限り、 回転テーブル 2 1に接するように設けられていて も、 図 3に示しているように、 回転テーブル 2 1の上方に設けられていてもよい。 また、 上杵用の粉体材料の塗布装置 3は、 平面視した場合には、 図 2に示すよ うに、 成形材料充填ボイント P 2の前段部に設けられている。 The powder material application device 3 for the upper punch is provided so as to be in contact with the rotary table 21 as long as it is provided below the rotation path Or of the plurality of upper punches 2 3. 3 may be provided above the turntable 21 as shown in FIG. In addition, when viewed in a plan view, the powder material application device 3 for the upper punch is provided at a front stage of the molding material filling point P2 as shown in FIG.
より詳しく説明すると、 上杵用の粉体材料の塗布装置 3は、 組となる下杵 2 4 が所定の位置まで挿入された臼 2 2の内周壁面 S 2 2及び下杵 2 4の上面 S 2 4 へ滑沢剤粉末を塗布する下杵用の粉体材料の塗布ボイント P 1 bとは別の位置、 即ち、 この例では、 錠剤排出ポイント P 5と、 下杵用の滑沢剤噴霧ポイント P 1 bとの間に設けられている。 More specifically, the powder material application device 3 for the upper punch is composed of an inner peripheral wall S 22 of the die 22 into which a pair of lower punches 24 are inserted to a predetermined position and an upper surface of the lower punch 24. Application point of powder material for lower punch to apply lubricant powder to S 2 4 A position different from P 1 b, that is, in this example, tablet discharge point P 5 and lubricant for lower punch It is provided between the spray point P 1 b.
そして、 上杵用の粉体材料の塗布装置 3の上面には、 複数の上杵 2 3 · · ·の 回転軌道 O rに沿って湾曲するように設けられ、 回転移動してくる、 複数の上杵 を、 順次、 収容する、 長尺な形状の上杵収容溝 3 1と、 上杵収容溝 3 1の底面に、 複数の上杵 2 3 · · ·の回転軌道 O rに沿って設けられ、 上杵収容溝 3 1内を移 動する複数の上杵 2 3 · ■ ·の下面 S 2 3 · · ·に、 空気脈動波の気流に分散さ れた滑沢剤剤粉末 Lを噴霧するスリット部 3 2とを備える。 On the upper surface of the powder material application device 3 for the upper punch, a plurality of upper punches 2 3 are provided so as to be curved along the rotation trajectory Or of the upper punches 2 3. The upper punches are sequentially accommodated, and are provided on the bottom surface of the long upper punch receiving groove 31 and the upper punch receiving groove 31 along the rotation path Or of the plurality of upper punches 23. The lubricant powder L dispersed in the pulsating air current is sprayed on the lower surface S2 3 of the upper punches 2 3 moving inside the upper punch receiving groove 3 1 And a slit portion 32 to be formed.
上杵収容溝 3 1は、 複数の上杵 2 3 · · 'の回転軌道 O rに沿うように湾曲し て設けられている。 The upper punch receiving groove 31 is provided so as to be curved along the rotation path Or of the plurality of upper punches 23.
そして、 上杵収宰溝 3 1の幅 W 3 1は、 複数の上杵 2 3 · · 'の各々の外径と 一致する幅か、 それよりやや大きい幅にされており、 上杵収容溝 3 1に収容され ている、 上杵 2 3の下面 S 2 3は、 スリット部 3 2から供給される滑沢剤粉末 L に曝され易くなつている一方、 上杵収容溝 3 1に収容されている、 上杵 2 3の側 周には、 滑沢剤粉末 Lが付着し難いようにされている。 The width W 3 1 of the upper punch grooving groove 3 1 is set to be equal to or slightly larger than the outer diameter of each of the plurality of upper punches 2 3. The lower surface S 23 of the upper punch 23 accommodated in the upper punch 23 is easily exposed to the lubricant powder L supplied from the slit portion 32, while being accommodated in the upper punch receiving groove 31. The lubricant powder L is hardly attached to the periphery of the upper punch 23.
尚、 図 4 ( a ) 中、 3 3は、 空気脈動波の気流に分散された滑沢剤剤粉末 Lを、 スリット部 3 2へ供給する、 滑沢剤剤粉末供給孔を示している。 In FIG. 4 (a), reference numeral 33 denotes a lubricant powder supply hole for supplying the lubricant powder L dispersed in the air current of the air pulsating wave to the slit portion 32.
そして、 滑沢剤剤粉末供給孔 3 3は、 図 2に示す、 接続用プレート 3 O pの上 面に設けられた接続口 e 8に接続されている。 The lubricant powder supply hole 33 is located on the connection plate 3 Op shown in FIG. It is connected to the connection port e8 provided on the surface.
この例では、 スリット部 32の上方には、 図 1、 図 2及び図 4 (b) に示すよ うに、 第 1の吸引手段 9の吸引ダクト T 4の吸引口 T 4 aが、 更に、 設けられて いる。 In this example, a suction port T4a of a suction duct T4 of the first suction means 9 is further provided above the slit portion 32, as shown in FIGS. It has been done.
図 5は、 吸引ダクト T4の吸引口 T4 aを中心にして、 その形状を概略的に示 す斜視図である。 FIG. 5 is a perspective view schematically showing the shape of the suction port T4a of the suction duct T4 centered on the suction port T4a.
この吸引口 T4aは、 スリット部 32の領域を覆う大きさを有しており、 且つ、 平面視した場合には、 複数の上杵 23 · · ·の回転軌道 Orの外周側に沿った形 状をしている。 The suction port T4a has a size to cover the area of the slit portion 32, and has a shape along the outer peripheral side of the rotation trajectory Or of the plurality of upper punches 23 in plan view. You are.
この例では、 吸引口 T4 aの内部には、 広い空間が形成されており、 その奥に、 第 1の吸引手段 (図 1に示す、 第 1の吸引手段 11) に接続される吸引ダクト T 4へ接続される配管 T 5が設けられた構造になっている。 In this example, a large space is formed inside the suction port T4a, and a suction duct T connected to the first suction means (the first suction means 11 shown in FIG. 1) is formed in the deep space. It has a structure in which a pipe T5 connected to 4 is provided.
尚、 図 5中、 e は、 配管 T 5の接続口を示しており、 この例では、 接続口 e 9は、 第 1の吸引手段 (図 1中に示す第 1の吸引手段 11) との接続が容易なよ うに、 接続用プレート 30 pの上面に設けられている。 In FIG. 5, e indicates a connection port of the pipe T5. In this example, the connection port e 9 is connected to the first suction means (the first suction means 11 shown in FIG. 1). It is provided on the upper surface of the connection plate 30p for easy connection.
そして、 第 1の吸引手段 11と接続口 e 9とは、 配管により接続される。 Then, the first suction means 11 and the connection port e9 are connected by a pipe.
以上の構成により、 第 1の吸引手段 11を駆動すれば、 この吸引口 T4aの形 状により、 スリット部 32の上方に、 スリット部 32から吸引口 T4aへ向かう 気流が発生し、 スリット部 32の上方に、 万遍なく、 スリット部 32から吸引口 T 4 aに向かう気流を発生させることができるようになつている。 With the above configuration, when the first suction means 11 is driven, an airflow from the slit 32 to the suction port T4a is generated above the slit 32 due to the shape of the suction port T4a. Upward, an airflow can be uniformly generated from the slit portion 32 toward the suction port T4a.
即ち、 第 1の吸引手段 11を駆動すれば、 上杵収容溝 31内を移動する、 上杵 23 · · ·の各々の下面 S 23 · · ·には、 上杵 23 · · ·の各々が、 順次、 ス リヅト部 32の起端部 esから終端部 e eまで移動する間に、 スリツト部 32よ り噴霧される、 正圧の空気脈動波の気流に混和し、 分散した滑沢剤粉末 Lは、 ス リット部 32から吸引口 T 4 aに向かう気流に乗って、 下方より上方に向かって、 概ね垂直方向に衝突し、 付着し続けることとなる。 That is, when the first suction means 11 is driven, the upper punch 23 moves in the upper punch receiving groove 31, and each of the upper punches 23 is placed on the lower surface S23 of the upper punch 23. While sequentially moving from the starting end es of the slit portion 32 to the end portion ee, the lubricant powder L which is sprayed from the slit portion 32 and is mixed with and dispersed in the airflow of the positive pressure air pulsating wave is dispersed. Riding on the airflow from the slit portion 32 toward the suction port T4a, collides upward in a substantially vertical direction from below and continues to adhere.
尚、 上杵 23 · · ·の各々の下面 S 23 · · ·への粉体材料の塗布時間は、 下 杵 24の上面 S 24及び曰 22の内周壁面 S 22への粉体材料の塗布時間を 「1」 とした場合には、 下杵 24の上面 S 24及び臼 22の内周壁面 S 22への粉体材 料の塗布時間の、 1倍以上 5 0倍以下であることが好ましく、 5倍以上 4 0倍以 下であることが、 更に、 好ましい。 The application time of the powder material to the lower surface S23 of each of the upper punches 23 is determined by the application time of the powder material to the upper surface S24 of the lower punch 24 and the inner peripheral wall surface 22 of the lower punch 22. When the time is set to “1”, the powder material on the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the mill 22 is The coating time is preferably 1 to 50 times, more preferably 5 to 40 times the coating time.
尚、 この関係は、 図 3 3に示す装置 4 Bのように、 スリット部 3 2.の代わりに、 複数の噴霧孔 h s · · ·を配列した場合も同様である。 Note that this relationship is the same when a plurality of spray holes h s ···· are arranged instead of the slits 3 2. as in the device 4B shown in FIG.
そして、 余分な滑沢剤粉末 Lは、 吸引口 T 4 a内に吸引されていく。 Then, the excess lubricant powder L is sucked into the suction port T4a.
このようにして、 この上杵用の粉^ ί料の塗布装置 3を用いれば、 重力との関 係で滑沢剤粉末 Lが付着し難い、 上杵 2 3 · · 'の各々の下面 S 2 3 · · ·に、 順次、 時間をかけて、 滑沢剤粉末 Lを、 均一に、 塗布できるようになつている。 更に、 この例では、 スリット部 3 2の幅 W 3 2が、 錠剤 tに形成する割線や刻 印の領域の幅に概ね一致するようにされている。 In this way, when the powder coating device 3 for the upper punch is used, the lubricant powder L hardly adheres due to the gravity and the lower surface S of each of the upper punches 2 3. 2 3 ··································································································································································· • Further, in this example, the width W32 of the slit portion 32 is made to substantially match the width of the area of the score line or the mark formed on the tablet t.
これにより、 この上杵用の粉体材料の塗布装置 3を用いれば、 上杵 2 3 · · · の各々の下面 S 2 3 · · ·の、 錠剤 tに、 割線や刻印を形成する部分、 即ち、 複 雑な凹凸が形成されている部分へも、 滑沢剤粉末 Lを、 万遍なく、 塗布できるた め、 錠剤を製造する際に、 上杵 2 3 · · 'の下面 S 2 3 · · ·の、 このような複 雑な凹凸が形成されている部分において、 ラミネ一ティングや、 キヤヅビングや、 スティッキング等の打錠障害を生じることなく、 錠剤を製造することができるよ うになる。 Thus, if the powder material applying device 3 for the upper punch is used, the lower surface S 23 of each of the upper punches 23, a portion forming a score line or a mark on the tablet t, That is, since the lubricant powder L can be applied evenly to the portion where the complex unevenness is formed, the lower surface S 2 3 of the upper punch 2 3 Tablets can be manufactured without causing tableting obstacles such as laminating, caving, and sticking in the portions where such complex irregularities are formed.
更に、 この上杵用の粉体材料の塗布装置 3では、 塗布装置 3の裏面 (回転テー ブル 2 1の表面に対向する表面) に、 凹所 (図 2中に破線で示す、 平面視した場 合、 概ね、 直角三角形形状の凹所 3 c ) を設けている。 且つ、 図 5に示しように、 導管 T 5を 2本の分岐管 T 5 a、 T 5 bに分岐し、 一方の分岐管 T 5 aを、 吸引 口 T 4 a側に接続し、 他方の分岐管 T 5 bを、 凹所 (図 2中に破線で示す、 平面 視した場合、 概ね、 直角三角形形状の凹所 3 c ) に接続するようにしている。 Further, in the powder material coating device 3 for the upper punch, a concave portion (shown by a broken line in FIG. 2 as viewed in a plan view) is formed on the back surface of the coating device 3 (the surface facing the surface of the rotating table 21). In this case, a generally right-angled triangular recess 3c) is provided. And, as shown in FIG. 5, the conduit T5 is branched into two branch pipes T5a and T5b, one branch pipe T5a is connected to the suction port T4a side, and The branch pipe T5b is connected to the recess (represented by a broken triangle 3c in a right-angled triangle when viewed in a plan view as indicated by a broken line in FIG. 2).
この構成により、 接続口 e 1に接^される第 1の吸引手段 (図示せず。 ) を駆 動すると、 上述したような、 吸引口 T 4 aに、 吸引口 T 4 a内へ向かう、 吸引雰 囲気の気流を発生できると同時に、 凹所 (図 2中に破線で示す、 平面視した場合、 概ね、 直角三角形形状の凹所 3 c ) において、 例え、 回転テーブル 2 1の表面に 成形材料や粉体材料 (この例では、 滑沢剤粉末) 等が付着していても、 回転テ一 ブル 2 1の表面に付着している、 成形材料や粉体材料 (この例では、 滑沢剤粉末) 等を除去できる。 With this configuration, when the first suction means (not shown) connected to the connection port e1 is driven, the suction port T4a, as described above, goes into the suction port T4a. At the same time as the air flow of the suction atmosphere can be generated, it is formed on the surface of the rotary table 21, for example, in a recess (shown by a broken line in FIG. 2, when viewed in a plan view, a generally triangular recess 3c). Even if a material or a powder material (in this example, a lubricant powder) is attached, a molding material or a powder material (in this example, a lubricant) is attached to the surface of the rotating table 21. Powder) Etc. can be removed.
これにより、 回転テーブル 21の表面を常にクリーンな状態に保つことができ るので、 不要な成形材料や粉体材料.(この例では、 滑沢剤粉末) に汚染されてい This keeps the surface of the turntable 21 clean at all times, and is contaminated with unnecessary molding material and powder material (in this example, lubricant powder).
、- ない、 錠剤を製造できる。 ,-No, tablets can be manufactured.
尚、 図 5は、 単なる例示であって、 吸引口 T4aと、 凹所 (図 2中に破線で示 す、 平面視した場合、 概ね、 直角三角形形状の凹所 3 c) とは、 接続口 e 9に接 続される第 1の吸引手段 11を駆動することによって、 吸引口 T 4 aに、 吸引口 T 4 a内に向かう吸引雰囲気の気流と、 凹所 (図 2中に破線で示す、 平面視した 場合、 概ね、 直角三角形形状の凹所 3 c) に、 凹所 (図 2中に破線で示す、 平面 視した場合、 概ね、 直角三角形形状の凹所 3 c) 内に向かう吸引雰囲気の気流と を同時に発生させる必要はなく、 接続口 e 9は、 凹所 (図 2中に破線で示す、 平 面視した場合、 概ね、 直角三角形形状の凹所 3 c) に接続され、 接続口 e 9に接 続される吸引手段 (図示せず。 ) を駆動すると、 凹所 (図 2中に破線で示す、 平 面視した場合、 概ね、 直角三角形形状の凹所 3 c) に、 凹所 (図 2中に破線で示 す、 平面視した場合、 概ね、 直角三角形形状の凹所 3 c) 内に向かう吸引雰囲気 の気流を発生でき、 吸引口 T 4 aに接続される接続口 (図示せず。 ) に、 第 1の 吸引手段 11を接続し、 第 1の吸引手段 11を駆動すれば、 吸引口 T 4 aに、 吸 引口 T 4 a内に向かう吸引雰囲気の気流を発生できるようにしてもよいことは、 言うまでもない。 Note that FIG. 5 is merely an example, and the suction port T4a and the recess (shown by a broken line in FIG. 2, when viewed in a plan view, are generally right-triangular-shaped recesses 3c) are the connection ports. By driving the first suction means 11 connected to the e 9, the suction port T 4 a is connected to the air flow of the suction atmosphere flowing into the suction port T 4 a, and the recess (shown by a broken line in FIG. 2). , When viewed in a plan view, a generally triangular-shaped recess 3 c) is drawn into the recess (shown by a broken line in FIG. 2, when viewed in a plan view, generally into a right-triangular shaped recess 3 c). It is not necessary to simultaneously generate the airflow of the atmosphere, and the connection port e 9 is connected to a recess (represented by a broken line in FIG. 2, which is generally a right triangle-shaped recess 3 c when viewed in a plan view), When the suction means (not shown) connected to the connection port e9 is driven, the recess (shown by a broken line in FIG. In the right triangle-shaped recess 3c), a suction atmosphere (shown by a broken line in Fig. 2, when viewed in a plan view) can be generated in the suction atmosphere toward the generally right triangle-shaped recess 3c). When the first suction means 11 is connected to a connection port (not shown) connected to the suction port T4a, and the first suction means 11 is driven, suction is performed on the suction port T4a. Needless to say, it may be possible to generate an airflow of a suction atmosphere toward the mouth T4a.
次に、 下杵用の粉体材料の塗布装置 4の構成について説明する。 Next, the configuration of the powder material applying device 4 for the lower punch will be described.
図 6は、 下杵用の粉体材料の塗布装置 4を概略的に説明する図であり、 図 6 (a) は、 図 2中、 I I一 I I線方向に見た斜視図を、 図 6 (b) は、 図 6 (a) 中、 VI— VI線に従う概略的な断面図であり、 また、 図 6 (c) は、 図 6 (b) に示した状態から一定時間が経過した状態を概略的に示す断面図である。 FIG. 6 is a diagram schematically illustrating a powder material application device 4 for a lower punch, and FIG. 6 (a) is a perspective view taken along the line II-II in FIG. (b) is a schematic cross-sectional view taken along the line VI-VI in FIG. 6 (a), and FIG. 6 (c) is a state after a certain time has elapsed from the state shown in FIG. 6 (b). It is sectional drawing which shows schematically.
下杵用の粉体材料の塗布装置 4は、 図 6 (a) 〜図 6 (c) の各々に示すよう に、 回転テーブル 21上に、 回転テーブル 21が摺動可能なように、 固定的に設 けられている。 The powder material application device 4 for the lower punch is fixed on the rotary table 21 so that the rotary table 21 can slide on the rotary table 21 as shown in FIGS. 6 (a) to 6 (c). It is located in
この塗布装置 4の、 回転テーブル 21に対向する側の表面 S 4 aは、 回転テー ブノレ 21が、 摺動できるように、 滑らかな表面にされている。 尚、 この塗布装置 4の、 回転テーブル 2 1に対向する側の表面 S 4 aは、 回転 テーブル 2 1の表面に接触しているか、 近接していることが好ましい。 The surface S 4 a of the coating device 4 on the side facing the rotary table 21 is made a smooth surface so that the rotary table 21 can slide. It is preferable that the surface S 4 a of the coating device 4 on the side facing the rotary table 21 is in contact with or close to the surface of the rotary table 21.
この塗布装置 4の、 回転テーブル 2 1に対向する側の表面 S 4 aは、 回転テー ブル 2 1の表面に近接させる場合には、 回転テーブル 2 1に対向する側の表面 S 4 aと、 回転テーブル 2 1の表面との隙間は、 狭ければ狭い程、 好ましい。 The surface S 4 a of the coating device 4 on the side facing the rotary table 21 is, when approaching the surface of the rotary table 21, a surface S 4 a on the side facing the rotary table 21. The smaller the gap with the surface of the turntable 21, the better.
より具体的に説明すると、 塗布装置 4の、 回転テーブル 2 1に対向する側の表 面 S 4 aと、 回転テーブル 2 1の表面との間の隙間は、 好ましくは、 1 0 0 /m 以下、 より好ましくは、 5 O ^m以下、 特に好ましくは、 3 0 m以下である。 このように、 塗布装置 4の、 回転テーブル 2 1に対向する側の表面 S 4 aと、 回転テーブル 2 1の表面との間の隙間を狭くすると、 この隙間を通って、 粉体材 料が、 飛散するという現象を防ぐことができる。 More specifically, the gap between the surface S4a of the coating device 4 on the side facing the rotary table 21 and the surface of the rotary table 21 is preferably 100 / m or less. It is more preferably 5 O ^ m or less, particularly preferably 30 m or less. As described above, when the gap between the surface S4a of the coating device 4 on the side facing the rotary table 21 and the surface of the rotary table 21 is reduced, the powder material passes through the gap. However, the phenomenon of scattering can be prevented.
尚、 このように塗布装置 4の、 回転テーブル 2 1に対向する側の表面 S 4 aを、 回転テーブル 2 1の表面に接近させるように設けることは、 後述する下杵用の塗 布装置 4 A、 4 B、 4 Dも同様である。 It should be noted that providing the surface S4a of the coating device 4 on the side facing the rotary table 21 so as to approach the surface of the rotary table 21 is not limited to the coating device 4 for a lower punch described later. The same is true for A, 4B, and 4D.
また、 この塗布装置 4の上面 S 4 bには、 空気脈動波に混和された滑沢剤粉末 Lを送り込む粉体材料導入口 e 1が設けられている。 Further, on the upper surface S 4 b of the coating device 4, a powder material inlet e 1 for feeding the lubricant powder L mixed with the air pulsating wave is provided.
粉体材料導入口 e 1には、 配管 T 3 bが接続されている。 The pipe T 3 b is connected to the powder material inlet e 1.
粉体材料導入口 e 1より送り込まれた滑沢剤粉末 Lは、 この装置 4を貫通する ように設けられた貫通孔 h 1を通って、 回転テーブル 2に対向する側の表面 S 4 a側に設けられた排出口 e 2に送られるようになつている。 The lubricant powder L sent from the powder material inlet e 1 passes through the through hole h 1 provided to penetrate the device 4, and the surface S 4 a on the side facing the rotary table 2. Is sent to the discharge port e2 provided in the
回転テーブル 2 1に対向する側の表面 S 4 aに送られ、 貫通孔 h iの回転テー ブリレ 2 1に対向する側の表面 S 4 a側の排出口 e 2より、 空気ととも排出された 滑沢剤粉末 Lは、 装置 4の下方に収容されている、 曰 2 2の内周壁面 S 2 2、 及 び、 臼 2 2内に所定の深さまで挿入された下杵 2 4の上面 S 2 4の概ね中心部に 概ね垂直方向に吹き付けられるようになつている (図 6 ( b ) を参照) 。 Slip is sent to the surface S 4 a on the side facing the rotary table 21 and is discharged with air from the outlet e 2 on the side S 4 a of the through hole hi on the side facing the rotary table 21. The powder powder L is accommodated below the device 4, the inner peripheral wall S 22 of 22, and the upper surface S 2 of the lower punch 24 inserted into the mortar 22 to a predetermined depth. 4 is designed to be sprayed in a substantially vertical direction at the center (see Fig. 6 (b)).
更に、 この装置 4には、 貫通孔 h 1の排出口 e 2から、 装置 4の下方に収容さ れている、 下杵 2 4及び曰 2 2に吹き付けられ、 下杵 2 4及び臼 2 2に余分に付 着している滑沢剤粉末 L、 及び、 回転テーブル 2 1上の余分な滑沢剤粉末 Lを除 去するための、 例えば、 ブロア等の第 2の吸引手段 (図示せず。 ) が接続されて いる。 Further, this device 4 is sprayed from a discharge hole e2 of a through hole h1 to a lower punch 24 and a box 22 which are housed below the device 4, and a lower punch 24 and a mill 22 A second suction means such as a blower (not shown) for removing the lubricant powder L that is attached to the rotary table and the excess lubricant powder L on the turntable 21; ) Is connected I have.
尚、 図 6中、 e 5'は、 第 2の吸引手段 (図示せず。 ) が接続される、 接続口を を示している。 In FIG. 6, e5 'indicates a connection port to which the second suction means (not shown) is connected.
第 2の吸引手段 (図示せず。 ) の吸引口 h 5は、 図 6 ( a ) に示すように、 回 転テーブル 2 1に設けられる、 複数の曰 2 2 · · 'の回転軌道 (図 6 ( a ) 中、 一点鎖線で示される回転軌道 O r ) に概ね直交するように、 且つ、 複数の臼 2 2 • · ·の各々及びそれらの周辺をカバ一できる長さのスリット状の形状を有して いる。 As shown in FIG. 6 (a), the suction port h5 of the second suction means (not shown) has a plurality of rotating orbits (see FIG. 6 (a), a slit-like shape that is substantially perpendicular to the rotation orbit O r) indicated by the dashed line, and that is long enough to cover each of the plurality of dies 2 2 have.
これにより、 図 6 ( c ) に示すように、 排出口 e 2より、 下杵 2 4の上面 S 2 4、 及び、 下杵 2 4が所定の位置まで挿入された曰 2 2の内周壁面 S 2 2に吹き 付けられ、 下杵 2 4の上面 S 2 4、 及び、 下杵 2 4が所定の位置まで挿入された 曰 2 2の内周壁面 S 2 2に、 余分に、 滑沢剤粉末 Lが、 付着、 堆積していたとし ても、 第 2の吸引手段 (図示せず。 ) を駆動させれば、 第 2の吸引手段 (図示せ ず。 ) の吸引口 h 5より、 下杵 2 4の上面 S 2 4、 及び、 下杵 2 4が所定の位置 まで挿入された曰 2 2の内周壁面 S 2 2に、 余分に、 付着、 堆積している滑沢剤 粉末 Lを除去できるので、 下杵 2 4の上面 S 2 4、 及び、 下杵 2 4が所定の位置 まで挿入された曰 2 2の内周壁面 S 2 2に、 余分な滑沢剤粉末 Lを付着、 堆積さ せずに、 これらの表面に、 滑沢剤粉末 Lを均一に塗布できるようになつている。 また、 回転テーブル 2 1の曰 2 2の周囲に、 滑沢剤粉末 Lが、 付着、 堆積して いても、 第 2の吸引手段 (図示せず。 ) を駆動させることにより、 吸引口 h 5よ り、 そのような滑沢剤粉末 Lを除去できるようになつている。 As a result, as shown in FIG. 6 (c), the upper surface S24 of the lower punch 24 and the lower peripheral punch 24 are inserted to a predetermined position from the discharge port e2. Sprayed onto S22, upper surface S24 of lower punch 24 and lower punch 24 inserted to predetermined position 22 Inner peripheral wall S22 Extra lubricant Even if the powder L adheres or accumulates, if the second suction means (not shown) is driven, the second suction means (not shown) can be moved downward from the suction port h5 of the second suction means (not shown). The lubricant powder L, which is extraly attached and deposited, is added to the inner peripheral wall S22 of the upper surface S24 of the punch 24 and the lower peripheral surface S22 where the lower punch 24 is inserted to a predetermined position. Since it can be removed, excess lubricant powder L adheres to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 24 into which the lower punch 24 has been inserted to a predetermined position. Without depositing on these surfaces, lubricant powder And summer so that L can be uniformly applied. Further, even if the lubricant powder L adheres and accumulates around the rotary table 21, the second suction means (not shown) drives the suction port h 5. Thus, the lubricant powder L can be removed.
これにより、 その後の成形材料を充填する工程において、 下杵 2 4及び曰 2 2 に余分に付着している滑沢剤粉末 L、 及び、 回転テーブル 2 1上の余分な滑沢剤 粉末 Lが、 成形材料 M中に、 混入することを防ぐことができるため、 錠剤 tを連 続打錠しても、 錠剤 t · · '間で、 滑沢剤粉末 Lの使用量に差のない錠剤を製造 できるようになつている。 As a result, in the subsequent step of filling the molding material, the lubricant powder L excessively adhering to the lower punch 24 and the statement 22 and the excess lubricant powder L on the rotary table 21 are removed. However, since it can be prevented from being mixed into the molding material M, even if the tablet t is continuously tableted, a tablet having the same amount of the lubricant powder L between the tablets t It can be manufactured.
また、 内部に、 滑沢剤粉末 Lを含むことの無い外部滑沢錠剤を、 効率よく製造 することもできるようになつている。 Further, an external lubricating tablet which does not contain the lubricant powder L therein can be efficiently produced.
更に、 この下杵用の粉体材料の塗布装置 4では、 図 6 ( c ) に示すように、 排 出口 e 2と、 吸引口 h 5との間の距離 L ( e 2 - h 5 ) を、 少なくとも、 曰 2 2 の直径 D 2 2に比べ、 長くなるようにしている。 Further, in the powder material application device 4 for the lower punch, as shown in FIG. The distance L (e 2-h 5) between the outlet e 2 and the suction port h 5 is set to be longer than at least the diameter D 22 of 22.
即ち、 この下杵用の粉体材料の塗布装置 4では、 第 2の吸引手段 (図示せず。 ) That is, in the powder material coating device 4 for the lower punch, the second suction means (not shown) is used.
、- の吸引口 h 5を、 少なくとも、 排出口 e 2が設けられている位置から、 回転テー ブル 2 1に設けられる、 複数の曰 2 2 . · ·の各々の直径 D 2 2より、 離れた位 置に設けている (L ( e 2 - h 5 ) > D 2 2 )。 The suction port h5 of,-is separated from at least the position of the discharge port e2 by a diameter D22 of each of a plurality of 22. (L (e2-h5)> D22).
従って、 この下杵用の粉体材料の塗布装置 4では、 下杵 2 4の上面 S 2 4及び 臼 2 2の内周壁面 S 2 2に塗布された粉体材料 (この例では、 滑沢剤粉末 L ) の 中、 下杵 2 4の上面 S 2 4及び曰 2 2の内周壁面 S 2 2にとつて余分な粉体材料 (この例では、 滑沢剤粉末 L ) を、 臼 2 2内に所定の位置まで挿入された下杵 2 4の上面 S 2 4に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける場所 (即ち、 排出口 e 2 ) とは、 臼 2 2を介して、 導通しない場所で、 吸引除去する ようにしているので、 臼 2 2内に所走の位置まで挿入された下杵 2 4の上面 S 2 4に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける条件に影響を与え ることなく、 下杵 2 4の上面 S 2 4及び曰 2 2の内周壁面 S 2 2に塗布された粉 体材料 (この例では、 滑沢剤粉末 L ) の中、 下杵 2 4の上面 S 2 4及び曰 2 2の 内周壁面 S 2 2にとつて余分な粉体材料 (この例では、 滑沢剤粉末 L ) を、 吸引 除去することができる。 Accordingly, in the powder material applying device 4 for the lower punch, the powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the die 22 (in this example, In the powder L), excess powder material (in this example, the lubricant powder L) is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24. The place where the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted to a predetermined position in the inside 2 (that is, the discharge port e 2) is a mill 2 2 , The air pulsation wave was dispersed on the upper surface S 24 of the lower punch 24 inserted into the mortar 22 to the position where it was run. The powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 24 without affecting the conditions for directly spraying the powder material (in this example, the lubricant Powder L), (In this example, wax powder L) punch 2 4 of the upper surface S 2 4 and 曰 2 2 of the inner circumferential wall surface S 2 extra powder material Te convex to 2, can be sucked and removed.
次に、 粉# ^料の吐出装置 (定量フィーダ) 5の構成について説明する。 Next, the configuration of the powder # ^ material discharge device (quantitative feeder) 5 will be described.
図 7は、 図 1中、 V I I部分を更に拡大して概略的に示す断面図である。 FIG. 7 is a sectional view schematically showing a VII portion in FIG. 1 in a further enlarged manner.
この粉体材料の吐出装置 5は、 ホッパー 5 1の下方に、 粉体材料切出弁 5 2を 介して接続された粉体材料貯留室 5 3と、 粉体材料貯留室 5 3の下方に設けられ た弾性膜体 5 4と、 粉体材料貯留室 5 3の下方に弾性膜体 5 4を介して接続され た b分散室 5 5とを備える。 The powder material discharge device 5 includes a powder material storage chamber 53 connected via a powder material cut-out valve 52 below the hopper 51, and a powder material storage chamber 53 below the powder material storage chamber 53. An elastic membrane 54 provided and a b dispersion chamber 55 connected below the powder material storage chamber 53 via the elastic membrane 54 are provided.
図 8は、 弾性膜体 5 4を概略的に示す平面図である。 FIG. 8 is a plan view schematically showing the elastic membrane 54.
弾性膜体 5 4は、 図 8に示すように、 その中央部に孔部 (スリット) 5 4 aを 備える。 As shown in FIG. 8, the elastic membrane 54 has a hole (slit) 54a at the center thereof.
粉体材料貯留室 5 3は、 ガラス又はアクリル樹脂等の樹脂等で製されており、 光透過性を有している。 そして、 粉体材料貯留室 5 3には、 図 7に示すように、 粉体材料貯留室 5 3に 内に貯留する滑沢剤粉末 Lの量を検出するレぺルセンサー 5 6が付設されている。 レベルセンサー 5 6は、 赤外線等の光を発光する発光素子 5 6 aと、 発光素子 5 6 aより照射された光を受光する 光素子 5 6 bとを備える。 The powder material storage chamber 53 is made of glass or a resin such as an acrylic resin, and has optical transparency. As shown in FIG. 7, the powder material storage chamber 53 is provided with a level sensor 56 for detecting the amount of the lubricant powder L stored in the powder material storage chamber 53. ing. The level sensor 56 includes a light emitting element 56 a that emits light such as infrared light, and an optical element 56 b that receives light emitted from the light emitting element 56 a.
発光素子 5 6 aと受光素子 5 6 bとは、 粉体材料貯留室 5 3を挟むようにして 対向配置されている。 The light emitting element 56 a and the light receiving element 56 b are arranged to face each other with the powder material storage chamber 53 interposed therebetween.
そして、 レベルセンサ一 5 6を設ける位置 (弾性膜体 5 4からレベルセンサ一 5 6の設けられる位置の高さ) H t hで、 粉体材料貯留室 5 3に貯留する滑沢剤 粉末 Lの量を検出できるようになつている。 Then, at the position where the level sensor 56 is provided (the height from the elastic film 54 to the position where the level sensor 56 is provided) H th, the lubricant powder L stored in the powder material storage chamber 53 The amount can be detected.
即ち、 粉^ 料貯留室 5 3に貯留する滑沢剤粉末 Lの量が、 レベルセンサ一 5 6を設ける位置 (弾性膜体 5 4からレベルセンサ一 5 6の設けられる位置の高さ) H t hを超えると、 発光素子 5 6 aより照射された光が、 滑沢剤粉末 Lに当り、 受光素子 5 6 bで受光できなくなる (オフになる。 ) ので、 この時、 粉体材料貯 留室 5 3内の滑沢剤粉末 Lの弾性膜体 5 4からの高さ Hが、 高さ H t hを超えて いることが検出できる (H > H t h) 。 That is, the amount of the lubricant powder L stored in the powder storage chamber 53 is the position where the level sensor 156 is provided (the height of the position where the level sensor 156 is provided from the elastic membrane 54) H When th exceeds th, the light emitted from the light emitting element 56a hits the lubricant powder L and cannot be received by the light receiving element 56b (turns off). At this time, the powder material is stored. It can be detected that the height H of the lubricant powder L in the chamber 53 from the elastic membrane 54 exceeds the height Hth (H> Hth).
また、 粉体材料貯留室 5 3に貯留する滑沢剤粉末 Lの量が、 レベルセンサー 5 6を設ける位置 (弾性膜体 5 4からレベルセンサ一 5 6の設けられる位置の高さ) H t h未満になると、 発光素子 5 6 aより照射された光が、 受光素子 5 6 bで受 光できる (オンになる。 ) ので、 この時、 粉体材料貯留室 5 3内の滑沢剤粉末 L の弾性膜体 5 4からの高さ Hが、 高さ H t h未満になっていることが検出できる Further, the amount of the lubricant powder L stored in the powder material storage chamber 53 is determined by the position where the level sensor 56 is provided (the height of the position where the level sensor 56 is provided from the elastic membrane 54) H th When the value is less than 5, the light emitted from the light emitting element 56a can be received by the light receiving element 56b (turned on). At this time, the lubricant powder L in the powder material storage chamber 53 is used. Height H from the elastic membrane 54 is less than the height H th
(H < H t h) 。 (H <Hth).
粉体材料切出手段 (粉体材料切出弁) 5 2は、 レベルセンサ一 5 6の検出値に 応じて、 上下に移動して、 ホッパー 5 1の排出口 5 1 aを閉じたり、 開いたりで きるようになつている。 The powder material extraction means (powder material extraction valve) 52 moves up and down according to the detection value of the level sensor 56 to close or open the discharge port 51 a of the hopper 51. It is now possible to use it.
より詳しく説明すると、 この装置 5では、 レベルセンサ一 5 6の検出値がオフ になれば、 粉体材料切出手段 5 2を上方に移動させて、 ホッパー 5 1の排出口 5 l aを閉じ、 レベルセンサー 5 6の検出値がオンになれば、 粉体材料切出手段 5 2を下方に移動させて、 ホッパー 5 1の排出口 5 1 aを開くようにして、 粉体材 料貯留室 5 3に、 常に、 概ね一定量の滑沢剤粉末 Lが貯留するようになつている。 また、 この例では、 分散室 55の形状が、 分散室 55内に旋回流を発生させや すいように、 概ね円筒形状にされている。 More specifically, in this device 5, when the detection value of the level sensor 56 is turned off, the powder material cutting means 52 is moved upward, and the discharge port 5 la of the hopper 51 is closed, When the detection value of the level sensor 5 6 is turned on, the powder material cutting means 52 is moved downward to open the discharge port 51 a of the hopper 51, and the powder material storage chamber 5 is opened. Third, an approximately constant amount of lubricant powder L is always stored. Further, in this example, the shape of the dispersion chamber 55 is substantially cylindrical so that a swirling flow is easily generated in the dispersion chamber 55.
尚、 ここでは、 分散室 55の形状を概ね円筒开娥にした例 示したが、 分散室. 55内に旋回流を発生できる限り、 分散室 55の形状は、 特に限定されることは ない。 Here, although an example is shown in which the shape of the dispersion chamber 55 is substantially cylindrical, the shape of the dispersion chamber 55 is not particularly limited as long as a swirling flow can be generated in the dispersion chamber 55.
また、 この分散室 55には、 その下方の位置に、 分散室 55の内周面の概ね接 線方向に、 空気脈動波を送り込む空気脈動波導入口 55 aが設けられている。 且つ、 分散室 55の上方の位置に、 分散室 55の内周面の概ね接線方向に、 空 気に混和され、 分散され、 流動化した粉体材料を分散室 55から排出する排出口 55 bを設けている。 The dispersion chamber 55 is provided with an air pulsation wave introduction port 55a for sending an air pulsation wave in a position substantially below the dispersion chamber 55 in a direction substantially tangential to the inner peripheral surface of the dispersion chamber 55. At the position above the dispersion chamber 55, in a direction substantially tangential to the inner peripheral surface of the dispersion chamber 55, an outlet 55b for discharging the powder material mixed, dispersed, and fluidized into the air from the dispersion chamber 55. Is provided.
ここで、 分散室 55に設ける空気脈動波導入口 55 aの位置について、 図 9を 用いて、 更に、 詳しく説明する。 Here, the position of the air pulsation wave introduction port 55a provided in the dispersion chamber 55 will be described in more detail with reference to FIG.
図 9は、 分散室 55を平面視した場合の、 分散室 55に設ける空気脈動波導入 口 55 aの位置を模式的に示す平面図であり、 図 9 (a) は、 空気脈動波導入口 55 aの理想的な取付け位置を説明する図であり、 また、 図 9 (b) は、 空気脈 動波導入口 55 aの実質的に可能な取付け位置を説明する図である。 FIG. 9 is a plan view schematically showing the position of the air pulsation wave introduction port 55a provided in the dispersion chamber 55 when the dispersion chamber 55 is viewed in a plan view. FIG. 9 (a) shows the air pulsation wave introduction port 55. FIG. 9B is a diagram illustrating an ideal mounting position of a, and FIG. 9B is a diagram illustrating a substantially possible mounting position of the air pulsation wave introduction port 55a.
尚、 図 9 (a) 及び図 9 (b) の各々に、 曲線で示す矢印は、 分散室 55内に 発生する空気脈動波旋回流の向きを模式的に示している。 In each of FIGS. 9 (a) and 9 (b), the curved arrows indicate the direction of the air pulsating wave swirling flow generated in the dispersion chamber 55.
分散室 55内に、 旋回流を発生させるためには、 空気脈動波導入口 55 aは、 図 9 (a) に示すように、 分散室 55の接線方向に設けるのが好ましい。 In order to generate a swirling flow in the dispersion chamber 55, the air pulsation wave introduction port 55a is preferably provided in the tangential direction of the dispersion chamber 55 as shown in FIG. 9 (a).
しかしながら、 空気脈動波導入口 55 aは、 図 9 (a) に示すように、 分散室 55の接線方向に厳密に設けられる必要はなく、 分散室 55内に、 支配的な 1個 の旋回流を形成できる限り、 図 9 (b) に示すように、 図 9 (a) に示した分散 室 55の接線 Lt方向と等価な方向 (即ち、 分散室 55のある接線 Ltに平行な 方向) に空気脈動波導入口 55 aが設けられていてもよい。 However, the air pulsation wave introduction port 55a does not need to be strictly provided in the tangential direction of the dispersion chamber 55 as shown in FIG. 9 (a), and one dominant swirling flow flows in the dispersion chamber 55. As far as possible, as shown in FIG. 9 (b), air flows in a direction equivalent to the tangent Lt direction of the dispersion chamber 55 shown in FIG. 9 (a) (that is, in a direction parallel to the tangent Lt where the dispersion chamber 55 is located). A pulsating wave introduction port 55a may be provided.
尚、 空気脈動波導入口 55 aを、 図 9 (b) に示すように、 分散室 55の中心 線 (図 9 (b) に想像線で示す中心線 Lcを参照) 方向に設けた場合には、 分散 室 55内の形状が円筒形状の場合、 いずれが支配的とも言えない 2個の旋回流が 発生するので好ましくない。 次いで、 分散室 55に設ける空気脈動波導入口 55 aと排出口 55bとの位置 関係について、 図 10を用いて、 更に 詳しく説明する。 When the air pulsation wave inlet 55a is provided in the direction of the center line of the dispersion chamber 55 (see the center line Lc shown by the imaginary line in FIG. 9 (b)) as shown in FIG. 9 (b). However, if the shape of the dispersion chamber 55 is cylindrical, it is not preferable because two swirling flows which cannot be said to be dominant are generated. Next, the positional relationship between the air pulsating wave introduction port 55a and the discharge port 55b provided in the dispersion chamber 55 will be described in more detail with reference to FIG.
図 10は、 分散室 55を平面視した場合の、 分散室 55に設ける空気脈動波導 入口 55 aと排出口 55 bとの位置関係を模式的に説明する図であり、 図 10 (a) は、 空気脈動波導入口 55 aと排出口 55 bとの実質的に可能な位置関係 を説明する図であり、 また、 図 10 (b) は、 空気脈動波導入口 55 aと排出口 55bとの好ましい位置関係を説明する図である。 FIG. 10 is a diagram schematically illustrating the positional relationship between the air pulsation wave inlet 55a and the outlet 55b provided in the dispersion chamber 55 when the dispersion chamber 55 is viewed in a plan view, and FIG. FIG. 10 is a view for explaining a substantially possible positional relationship between the air pulsation wave introduction port 55a and the discharge port 55b, and FIG. 10 (b) shows a preferred relationship between the air pulsation wave introduction port 55a and the discharge port 55b. It is a figure explaining a positional relationship.
また、 図 10 (a) 及び図 10 (b) の各々に、 曲線で示す矢印は、 分散室 5 5に発生する空気脈動波の旋回流の向きを模式的に示している。 In each of FIGS. 10 (a) and 10 (b), the arrow indicated by a curve schematically indicates the direction of the swirling flow of the air pulsation wave generated in the dispersion chamber 55.
分散室 55に、 排出口 55 bを、 図 10 (a) に示すような位置に設けた場合 には、 分散室 55に発生する空気脈動波の旋回流の向き (空気の進行方向) と逆 方向に排出口 55bが設けられる関係になり、 排出口 55bにおける、 空気に分 散させて流動化している滑沢剤粉末 Lの排出効率がよいとは言えない。 When the outlet 55b is provided in the dispersing chamber 55 at the position shown in Fig. 10 (a), the direction of the swirling flow of the air pulsating wave generated in the dispersing chamber 55 (the traveling direction of air) is reversed. In this case, the discharge port 55b is provided in the direction, and the discharge efficiency of the lubricant powder L dispersed in the air and fluidized at the discharge port 55b cannot be said to be good.
排出口 55 bにおける、 空気に分散させて流動化している滑沢剤粉末 Lの排出 効率を考慮した場合には、 図 10 (b) に、 例示的に示す、 排出口 55b 1又は 排出口 55b2のように、 分散室 55に発生する空気脈動波の旋回流の向き (空 気の進行方向) と順方向に、 排出口 55 bが設けられる関係になっていることが、 どちらかというと、 好ましい。 In consideration of the discharge efficiency of the lubricant powder L dispersed and dispersed in the air at the discharge port 55b, the discharge port 55b1 or the discharge port 55b2 is exemplified in FIG. 10 (b). As shown in the above, the discharge port 55b is provided in the forward direction with the direction of the swirling flow of the air pulsation wave generated in the dispersion chamber 55 (the traveling direction of the air). preferable.
この例では、 分散室 55の空気脈動波導入口 55 aには、 配管 T 2を介して、 空気脈動波発生装置 7が接続されている。 In this example, an air pulsation wave generator 7 is connected to the air pulsation wave introduction port 55a of the dispersion chamber 55 via a pipe T2.
また、 排出口 55bは、 配管 T3を介して、 上杵用の粉体材料の塗布装置 3の 粉体材料導入口 33及び下杵用の粉体材料の塗布装置 4の粉体材料導入口 e 1に 接続されている。 The outlet 55b is connected to the powder material inlet 33 of the powder material applying device 3 for the upper punch and the powder material inlet 33 of the powder material applying device 4 for the lower punch via the pipe T3. Connected to 1.
尚、 図 7中、 57に示す部材装置は、 粉体材料切出手段 52の動作を確認する ために設けられた CCDカメラ等の撮像手段を、 58に示す部材装置は、 レーザ 光線等の光を照射するとともに、 ホッパー 51の排出口 5 l aより落下する滑沢 剤粉末 (図示せず。 ) により散乱した散乱光を受光することにより、 ホッパー 5 1の排出口 51 aより落下する滑沢剤粉末 (図示せず。 ) の状態を調べるセンサ —を、 また、 59に示す部材装置は、 レーザ光線等の光を照射するとともに、 弾 性膜体 5 4の孔部 (スリット) 5 4 άより落下し、 分散室 5 5内に発生させてい る旋回流の空気脈動波に巻き込まれ、 混和し、 分散し、 流動化している粉 料 (図示せず。 ) により散乱した散乱光を受光することにより、ヽ-混合室 5 5内の粉 体材料 (図示せず。 ) の状態を調べるセンサ一を、 各々、 示している。 In FIG. 7, a member device indicated by 57 is imaging means such as a CCD camera provided to confirm the operation of the powder material cutting means 52, and a member device indicated by 58 is light such as a laser beam. , And receives the scattered light scattered by the lubricant powder (not shown) falling from the outlet 5 la of the hopper 51, so that the lubricant falls from the outlet 51 a of the hopper 51. A sensor for checking the state of the powder (not shown). The member device shown at 59 irradiates light such as a laser beam, The material that falls from the hole (slit) 54 of the porous membrane 54 and is entrained by the swirling air pulsating wave generated in the dispersion chamber 55, and is mixed, dispersed, and fluidized (Not shown), each of which shows a sensor for checking the state of the powder material (not shown) in the ヽ -mixing chamber 55 by receiving the scattered light scattered by the.
また、 6 0で示す部材装置は、 発光素子 6 0 aと受光素子 6 O bとを備えて構 成されたレペルセンサ一を示しており、 この例では、 このレベルセンサー 6 0に より、 ホヅパー 5 1内の粉体材料の残量を検出するようにしている。 Further, a member device indicated by 60 indicates a repel sensor configured to include a light emitting element 60a and a light receiving element 6Ob. In this example, the level sensor 60 is used to control the hopper 5a. The remaining amount of the powder material in 1 is detected.
尚、 これらの部材装置 5 7、 5 8、 5 9、 6 0は、 必要により設けられるもの である。 These member devices 57, 58, 59, 60 are provided as necessary.
次に、 この粉体材料の吐出装置 5の動作について説明する。 Next, the operation of the powder material discharging device 5 will be described.
まず、 この吐出装置 5を用いて、 上杵用の粉体材料の塗布装置 3及び下杵用の 粉体材料の塗布装置 4の各々に、 空気に混和し、 分散し、 流動化した滑沢剤粉末 First, using this discharge device 5, each of the powder material application device 3 for the upper punch and the powder material application device 4 for the lower punch is mixed with air, dispersed, and fluidized lubricant. Agent powder
Lを供給するには、 まず、 滑沢剤粉末 Lを、 ホッパー 5 1内に収容し、 レぺルセ ンサー 5 6を動作状態にする。 To supply L, first, lubricant powder L is stored in hopper 51, and rail sensor 56 is activated.
この状態では、 レベルセンサー 5 6の発光素子 5 6 aから照射される赤外線等 の光は、 受光素子 5 6 bによって受光されているので、 受光素子 5 6 bは、 オン になっている。 In this state, since light such as infrared rays emitted from the light emitting element 56a of the level sensor 56 is received by the light receiving element 56b, the light receiving element 56b is turned on.
次に、 粉体材料切出手段 5 2を開き、 粉体材料貯留室 5 3内に、 滑沢剤粉末 L を落下させる。 Next, the powder material cutting means 52 is opened, and the lubricant powder L is dropped into the powder material storage chamber 53.
粉体材料貯留室 5 3内に、 滑沢剤粉末 Lが落下堆積し、 粉体材料貯留室 5 3内 に堆積した滑沢剤粉末 Lの弾性膜体 5 4からの高さ Hが、 レベルセンサー 5 6の 設けられている位置の高さ H t hを超えると、 発光素子 5 6 aから照射される赤 外線等の光が、 粉体材料貯留室 5 3内に堆積した滑沢剤粉末 Lにより遮られるた め、 受光素子 5 6 bが、 発光素子 5 6 aから照射される光を受光できなくなるの で、 受光素子 5 6 bは、 オフなる。 この時、 自動的に、 粉体材料切出手段 5 2が 閉じた状態になるので、 滑沢剤粉末 Lが、 弾性膜体 5 4から概ね所定の高さ H t hになるまで収容される (H二 H t h) 。 Lubricant powder L falls and accumulates in the powder material storage chamber 53, and the height H of the lubricant powder L accumulated in the powder material storage chamber 53 from the elastic film 54 increases to the level. When the height exceeds the height H th of the position where the sensor 56 is provided, light such as infrared rays emitted from the light-emitting element 56 a emits lubricant powder L deposited in the powder material storage chamber 53. The light receiving element 56 b is turned off because the light receiving element 56 b cannot receive the light emitted from the light emitting element 56 a. At this time, since the powder material cutting means 52 is automatically closed, the lubricant powder L is stored from the elastic membrane 54 to a height Hth which is approximately equal to a predetermined height ( H2Hth).
次に、 空気源 7を駆動し、 演算器 (コントローラ) 9を用いて、 流量制御装置 1 2を調整し、 空気脈動波発生装置 8のモー夕等の駆動源 mを所望の速度で動か すことにより、 正圧の空気脈動波を配管 T 2内に発生させる。 Next, the air source 7 is driven, the flow controller 12 is adjusted using the computing unit (controller) 9, and the driving source m of the air pulsation wave generator 8, such as a motor, is moved at a desired speed. As a result, a positive pressure air pulsation wave is generated in the pipe T2.
この粉体材料の吐出装置 5では、 分散室 5 5の下方の位置に、 分散室 5 5の内 周面の接線方向又はこれと等価な方向に、 空気脈動波を送り込 、-む空気脈動波導入 口 5 5 aを設け、 且つ、 分散室 5 5の上方の位置に、 分散室 5 5の内周面に、 分 散室 5 5内で、 旋回流になっている空気脈動波の進行方向に、 概ね順方向に排出 口 5 5 bを設けているので、 空気脈動波導入口 5 5 aより分散室 5 5内に送り込 まれた空気脈動波は、 図 7に示すように、 分散室 5 5内で、 空気脈動波導入口 5 5 aから、 排出口 5 5 bに向かう、 下方から上方に向かう旋回流 (竜巻のような 渦巻き流) の空気脈動波になる。 In the powder material discharge device 5, air pulsation waves are sent to a position below the dispersion chamber 55 in the tangential direction of the inner peripheral surface of the dispersion chamber 55 or in a direction equivalent thereto. A wave introduction port 55a is provided, and at the position above the dispersing chamber 55, on the inner peripheral surface of the dispersing chamber 55, and in the dispersing chamber 55, the progress of swirling air pulsating waves As shown in Fig. 7, the air pulsation wave sent into the dispersion chamber 55 from the air pulsation wave introduction port 55a has a discharge port 55b in the forward direction. Within 55, an air pulsation wave of a swirling flow (a tornado-like swirl flow) from the air pulsation wave introduction port 55a to the discharge port 55b, going upward from below.
この分散室 5 5内で発生した、 旋回流の空気脈動波は、 空気脈動波の性質は失 われていないため、 弾性膜体 5 4は、 空気脈動波の周波数、 振幅、 波形に従って 振動する。 Since the swirling air pulsation wave generated in the dispersion chamber 55 does not lose the property of the air pulsation wave, the elastic membrane 54 vibrates according to the frequency, amplitude, and waveform of the air pulsation wave.
図 1 1は、 分散室 5 5内に、 空気脈動波を送り込んだ際に、 弾性膜体 5 4に生 じる現象を模式的に説明する説明図である。 FIG. 11 is an explanatory diagram schematically illustrating a phenomenon that occurs in the elastic membrane 54 when an air pulsation wave is sent into the dispersion chamber 55.
例えば、 分散室 5 5内に送り込まれる空気脈動波が山の状態になり、 分散室 5 5内の圧力が高くなると、 弾性膜体 5 4が、 図 1 1 ( a ) に示すように、 弾性変 形して、 上方に湾曲する。 For example, when the air pulsation wave sent into the dispersion chamber 55 becomes a mountain state and the pressure in the dispersion chamber 55 increases, the elastic membrane 54 becomes elastic as shown in FIG. 11 (a). It deforms and curves upward.
このとき、 孔部 (スリット) 5 4 aの上側が開いた V字状態になり、 スリット 7 3 aの開いた状態にされた部分に、 粉体材料貯留室 5 3内に貯留されている滑 沢剤粉末 Lの一部が落下する。 At this time, the upper side of the hole (slit) 54 a is in a V-shaped state in which the upper side is opened, and the slip stored in the powder material storage chamber 53 is in a portion where the slit 73 a is opened. A part of powder powder L falls.
次いで、 例えば、 分散室 5 5内に送り込まれる空気脈動波が山から谷へ移行し て、 分散室 5 5内の圧力が下がってくると、 弾性変形して、 上方に湾曲していた 弾性膜体 5 4が復元力により、 元の状態に戻ってくる。 Next, for example, when the air pulsating wave sent into the dispersion chamber 55 transitions from a peak to a valley and the pressure in the dispersion chamber 55 decreases, it elastically deforms and is elastically curved upward. The body 54 returns to its original state by restoring force.
このとき、 上側が開いた状態にされていた孔部 (スリット) 5 4 aも元の状態 に戻るため、 孔部 (スリット) 5 4 aの上側が開いた状態にされた部分に落下し た滑沢剤粉末 Lの一部が孔部 (スリット) 5 4 aに挟み込まれた状態になる (図 1 1 ( b ) を参照) 。 At this time, the hole (slit) 54a, whose upper side was opened, also returned to its original state, and thus fell into the part where the upper side of the hole (slit) 54a was opened. A part of the lubricant powder L is sandwiched between the holes (slits) 54a (see FIG. 11 (b)).
次いで、 例えば、 分散室 5 5内に送り込まれる空気脈動波が谷側へ移行して、 分散室 5 5内の圧力が下がってくると、 図 1 1 ( c ) に示すように、 元の状態に 戻っていた弾性膜体 5 4が、 復元力並びに混合室内の圧力が下がるのに対応して、 弾性変形して、 下方に湾曲する。 Next, for example, when the air pulsating wave sent into the dispersion chamber 55 moves to the valley side and the pressure in the dispersion chamber 55 decreases, as shown in Fig. 11 (c), the original state To The returned elastic membrane 54 elastically deforms and curves downward in response to the decrease in the restoring force and the pressure in the mixing chamber.
このとき、 孔部 (スリット) 5 4 aの下側が開いた逆 V字状態になり、 ?し部 (スリット) 5 4 a内に挟まれていた滑沢剤粉末 が、 分散室 5 5内に落下する。 そして、 分散室 5 5内に落下した滑沢剤粉末 Lは、 混合室 5 5内を旋回してい る空気脈動波に混和し、 分散して、 流動化して、 排出口 5 5 bより空気とともに、 配管 T 3に送り出される。 . At this time, the lower part of the hole (slit) 54a is in an inverted V-shape, and? The lubricant powder sandwiched between the slits 54 a falls into the dispersion chamber 55. The lubricant powder L that has fallen into the dispersion chamber 55 mixes with the air pulsating wave swirling in the mixing chamber 55, disperses and fluidizes, and flows with air from the discharge port 55b. Is sent out to the pipe T3. .
この吐出装置 5では、 空気脈動波の周波数、 振幅、 波形に応じて、 弾性体膜 5 4の周波数、 振幅、 波形が定まって振動するので、 空気脈動波の周波数、 振幅、 波形を制御するだけで、 配管 T 3内に、 一定量の粉体材料を空気とともに安定し て供給することができるという利点がある。 In the discharge device 5, since the frequency, amplitude, and waveform of the elastic film 54 are determined and vibrated according to the frequency, amplitude, and waveform of the air pulsation wave, only the frequency, amplitude, and waveform of the air pulsation wave are controlled. Therefore, there is an advantage that a certain amount of powder material can be stably supplied together with air into the pipe T3.
更に、 この装置 5では、 分散室 5 5内において、 空気脈動波が、 下方から上方 に向かう旋回流にされているので、 分散室 5 5内に落下した粉体材料中、 粒径の 大きい粒子の多くは、 この旋回流に巻き込まれ、 所望の粒怪まで碎かれて、 排出 口 5 5 bより排出される。 Furthermore, in this device 5, since the air pulsation wave is made into a swirling flow from the lower side to the upper side in the dispersion chamber 55, particles having a large particle diameter in the powder material dropped into the dispersion chamber 55 Most of the water is caught in this swirling flow, broken down to the desired grain size, and discharged from the outlet 55b.
また、 分散室 5 5内に、 下方から上方に向かう旋回流を発生させたので、 分散 室 5 5はサイクロンと同様の、 分粒機能を有している。 これにより、 旋回流によ つて砕かれなかった大きな粒子は、 分散室 5 5内の下方の位置に、 所定の粒径に 砕かれ迄で滞留するので、 大きな粒子が、 上杵用の粉体材料の塗布装置 3及び下 杵用の粉体材料の塗布装置 4の各々に送り込まれることがない。 In addition, since a swirling flow is generated in the dispersion chamber 55 from the lower side to the upper side, the dispersion chamber 55 has a sizing function similar to a cyclone. As a result, the large particles that are not broken by the swirling flow stay at the lower position in the dispersion chamber 55 until they are crushed to a predetermined particle size. It is not fed into each of the material application device 3 and the powder material application device 4 for the lower punch.
したがって、 この装置 5を用いれば、 常に概ね一定量の滑沢剤粉末 Lを安定し て連続的に、 しかも、 滑沢剤粉末 Lの粒径を均一にして、 排出口 5 5 bより排出 できる。 Therefore, if this device 5 is used, a substantially constant amount of the lubricant powder L can be constantly and continuously discharged, and the lubricant powder L has a uniform particle size, and can be discharged from the discharge port 55b. .
また、 この装置 5を用いれば、 粒径の大きい粒子の大部分が、 旋回流にされた 空気脈動波によって、 所望の大きさに碎かれ、 排出口 5 5 bより排出されるので、 分散室 5 5内に粒径の大きい粒子が堆積し難い。 Also, if this device 5 is used, most of the particles having a large particle size are crushed into a desired size by the swirling air pulsating wave, and are discharged from the discharge port 55b. 5 Large particles are difficult to deposit in 5.
これにより、 分散室 5 5内を清掃する作業回数を減らすことができる。 As a result, the number of operations for cleaning the inside of the dispersion chamber 55 can be reduced.
このように、 この外部滑沢式打錠機 1では、 装置 5を使用しているので、 連続 打錠工程を行っている最中に、 分散室 5 5内を清掃する作業を行う必要がなくな る o As described above, since the external lubricating tablet press 1 uses the device 5, it is not necessary to clean the inside of the dispersing chamber 55 during the continuous tableting process. What O
従って、 この外部滑沢式打錠機 1で錠剤を製造すれば、 錠剤を製造している間 に、 分散室 5 5を清掃する必要がなくなるため、 生産性が極めて高くなる。 Therefore, if tablets are manufactured with this external lubricating tableting machine 1, it is not necessary to clean the dispersing chamber 55 while manufacturing the tablets, so that productivity is extremely increased.
、- また、 空気脈動波導入口 5 5 aを分散室 5 5の下方に設け、 排出口 5 5 bを分 散室 5 5の上方に設けているので、 分散室 5 5内において、 空気脈動波導入口 5 5 aと排出口 5 5 bとが、 互いに、 対向しない。 The air pulsation wave introduction port 55a is provided below the dispersion chamber 55, and the discharge port 55b is provided above the distribution chamber 55. The inlet 55a and the outlet 55b do not face each other.
これにより、 空気脈動波導入口 5 5 aより送り込まれた空気脈動波が、 直接、 排出口 5 5 bに入らず、 必ず、 分散室 5 5内を旋回した後に、 排出口 5 5 bに入 るため、 分散室 5 5内において、 空気脈動波を有効利用できる。 As a result, the air pulsation wave sent from the air pulsation wave introduction port 55a does not directly enter the discharge port 55b, but always enters the discharge port 55b after turning inside the dispersion chamber 55. Therefore, the air pulsation wave can be effectively used in the dispersion chamber 55.
また、 排出口 5 5 bを、 分散室 5 5の内周面に設けているので、 排出口 5 5 b に、 弾性膜体 5 4の孔部 (スリット) 5 4 aから落下した滑沢剤粉体 Lが、 空気 と混和せずに、 直接、 排出口 5 5 b内に入るという現象も生じない。 In addition, since the discharge port 55b is provided on the inner peripheral surface of the dispersion chamber 55, the lubricant dropped from the hole (slit) 54a of the elastic membrane 54 at the discharge port 55b. There is no phenomenon that the powder L directly enters the discharge port 55b without being mixed with air.
更にまた、 粒子の大きい滑沢剤粉末 Lの大部分を使用できるので、 滑沢剤粉末 Lを有効利用できるという効果もある。 Furthermore, since most of the lubricant powder L having large particles can be used, there is an effect that the lubricant powder L can be effectively used.
更に、 この装置 5では、 分散室 5 5内において、 空気脈動波が、 下方から上方 に向かう旋回流にされているので、 分散室 5 5内に落下した粉 料中、 粒径の 大きい粒子の多くは、 この旋回流に巻き込まれ、 所望の粒径まで砕かれて、 排出 口 5 5 bより排出される。 Further, in this device 5, since the air pulsation wave is made into a swirling flow from the lower side to the upper side in the dispersion chamber 55, the particles having a large particle diameter in the powder dropped into the dispersion chamber 55 are removed. Most are entrained in this swirling flow, crushed to a desired particle size, and discharged from the outlet 55b.
更に、 この粉体材料の吐出装置 5では、 粉体材料貯留室 5 3に、 粉体材料貯留 室 5 3内に貯留する滑沢剤粉末 Lの量を検出するレベルセンサ一 5 6を設け、 粉 料貯留室 5 3の上方にホッパー 5 1を、 粉体材料切出手段 5 2を介在させて 接続し、 レベルセンサ一 5 6の検出値がオフになれば、 粉体材料切出手段 5 2を 閉じ、 レベルセンサー 5 6の検出値がオンになれば、 粉体材料切出手段 5 2を開 き、 粉体材料貯留室 5 3に、 常に、 概ね一定量の滑沢剤粉末 Lが貯留されるよう にしている。 Further, in the powder material discharge device 5, the powder material storage chamber 53 is provided with a level sensor 56 for detecting the amount of the lubricant powder L stored in the powder material storage chamber 53. The hopper 51 is connected above the powder storage chamber 53 with the powder material cutting means 52 interposed, and if the detection value of the level sensor 56 turns off, the powder material cutting means 5 2 is closed and when the detection value of the level sensor 5 6 is turned on, the powder material cutting means 52 is opened, and an approximately constant amount of the lubricant powder L is always stored in the powder material storage chamber 53. They are being stored.
これにより、 空気脈動波を一定にすることで、 常に、 一定量の滑沢剤粉末 Lを、 弾性膜体 5 4の孔部 (スリット) 5 4 aより排出することができる。 Thus, by keeping the air pulsation wave constant, a certain amount of the lubricant powder L can always be discharged from the hole (slit) 54 a of the elastic membrane 54.
尚、 この例では、 センサーとして、 レベルセンサー 5 6を用いたものを説明し たが、 これは、 単に、 好ましい例を説明したに過ぎず、 粉体材料貯留室 5 3内の 滑沢剤粉末 Lの量を検出できるものであれば、 重量センサ一等の種々のセンサ一 を用いることができる。 In this example, the sensor using the level sensor 56 has been described as a sensor. However, this is merely a preferred example, and the level sensor 56 in the powder material storage chamber 53 is described. As long as the amount of the lubricant powder L can be detected, various sensors such as a weight sensor can be used.
次に、 この外部滑沢式打錠機 1で用いる空気脈動波発生装置 8の構成について 説明する。 Next, the configuration of the air pulsation wave generator 8 used in the external lubricating tableting machine 1 will be described.
この外部滑沢式打錠機 1では、 空気脈動波発生装置 8として、 種々の装置を用 いることができる。 In the external lubricating tablet press 1, various devices can be used as the air pulsation wave generator 8.
そのような空気脈動波発生装置 8としては、 コンプレッサーやブロア等の空気 源 7によって発生させた一定圧の圧縮空気を電磁弁を開閉して空気脈動波にした り、 又は、 空気源 7によって発生させた一定圧の圧縮空気を空気導入口より所定 のケース内に供給し、 ケース内に、 ケースに設けられた排出口を開閉する、 回転 可能に設けられた口一タリ型の弁体を設け、 口一夕リ型の弁体を回転させたりす ることによつても発生させるものであってもよい。 As such an air pulsation wave generator 8, a constant pressure compressed air generated by an air source 7 such as a compressor or a blower is opened and closed by an electromagnetic valve to generate an air pulsation wave, or generated by the air source 7. The compressed air at a constant pressure is supplied from the air inlet into a predetermined case, and a rotatable one-way valve is provided in the case to open and close the discharge port provided in the case. Alternatively, it may be generated by rotating a mouth-type valve body.
しかしながら、 このような方法で発生できる空気脈動波は、 粉体材料の物性に 応じて、 粉 料を効率よく空気に混和し、 分散し、 流動化させる、 所望の ¾¾、 振幅、 周期の空気脈動波を発生させ難い、 という問題がある。 However, the pulsating air pulsation generated by such a method can cause the powder to efficiently mix, disperse, and fluidize the air depending on the physical properties of the powder material, and generate air pulsations having a desired ¾¾, amplitude, and period. There is a problem that it is difficult to generate waves.
このようなことを考慮したり、 減衰し難い空気脈動波を必要とする場合には、 図 1 2に示すような空気脈動波発生装置を用いるのが好ましい。 In consideration of this, or when an air pulsation wave that is hard to attenuate is required, it is preferable to use an air pulsation wave generator as shown in FIG.
図 1 2は、 そのような空気脈動波発生装置を概略的に示す断面図である。 FIG. 12 is a sectional view schematically showing such an air pulsation wave generator.
この空気脈動波発生装置 8は、 入力ポート 8 1と出力ポート 8 2との間に弁座 8 3を設けた弁室 8 4に、 カム機構 8 5によって開閉する弁体 8 6とを備える。 カム機構 8 5は、 モー夕一等の駆動手段 (図示せず) により回転可能に設けら れた回転カム 8 7と、 弁体 8 6の下端に取着されたローラ 8 8とを備える。 The air pulsation wave generator 8 includes a valve chamber 86 provided with a valve seat 83 between an input port 81 and an output port 82, and a valve body 86 opened and closed by a cam mechanism 85. The cam mechanism 85 includes a rotating cam 87 rotatably provided by a driving means (not shown) such as a motor or the like, and a roller 88 attached to a lower end of the valve body 86.
弁座 8 3は、 出力ポート 8 2方向に先すぼんだ形状の孔部にされており、 弁体 8 6は、 弁座 8 3の形状に合わせた先すぼんだ逆すり鉢形状にされており、 弁座 8 3を気密に塞ぐことができるようになつている。 The valve seat 83 is formed into a hole with a shape that is tapered in the direction of the output port 82, and the valve element 86 is formed into a tapered inverted mortar shape that matches the shape of the valve seat 83. The valve seat 83 can be airtightly closed.
また、 この例では、 弁体 8 6の軸部 8 6 aが、 ケース体 8 9の軸孔 8 9 h内に、 空気がもれないように、 且つ上下に移動自在に設けられている。 Further, in this example, the shaft portion 86a of the valve body 86 is provided in the shaft hole 89h of the case body 89 so as to be free of air and to be vertically movable.
ローラ 8 8は、 回転カム 8 7に、 回転可能に挟持され、 回転カム 8 7を回転す ることで、 回転カム 8 7に設けられた凹凸パターンに従って、 回転しながら上下 動するようになっている。 The roller 88 is rotatably sandwiched by the rotating cam 87, and by rotating the rotating cam 87, the roller 88 moves up and down while rotating according to the uneven pattern provided on the rotating cam 87. It works.
より詳しく説明すると、 回転カム 8 7は、 内側回転カム 8 7 aと外側回転カム 8 7 bとを備えている。 、- 内側回転カム 8 7 a及び外側回転カム 8 7 bの各々には、 凹凸パターンが、 口 ラ一8 8の間隔を保持するように且つ互いに整列するように設けられている。 そして、 ローラ 8 8は、 内側回転カム 8 7 aと外側回転カム 8 7 bとの間に挟 持され、 弁体 8 6にハネを生じることがなく、 回転カム 8 7を回転させることで、 内側回転カム 8 7 aと外側回転カム 8 7 bとに設けられた凹凸パターンに従って、 回転しながら上下動するようになっている。 More specifically, the rotating cam 87 includes an inner rotating cam 87a and an outer rotating cam 87b. Each of the inner rotating cam 87a and the outer rotating cam 87b is provided with a concave / convex pattern so as to keep a gap between the apertures 88 and align with each other. The roller 88 is sandwiched between the inner rotating cam 87a and the outer rotating cam 87b, and by rotating the rotating cam 87 without causing splash on the valve body 86, In accordance with the concave / convex pattern provided on the inner rotating cam 87a and the outer rotating cam 87b, it moves up and down while rotating.
尚、 この回転カム 8 7に設ける凹凸パターンは、 滑沢剤粉末 Lの物性に応じて、 異なったパターンのものが選択される。 The uneven pattern provided on the rotating cam 87 is selected from different patterns according to the physical properties of the lubricant powder L.
また、 この例では、 入力ポート 8 1に流量制御装置 1 2が、 配管 T 1を介して 接続されており、 入力ボート 8 1には、 空気源 7で発生させ、 流量制御装置 1 2 により所定の流量に調整された圧縮空気が供給されるようになっている。 In this example, a flow control device 12 is connected to the input port 81 via a pipe T1, and the input boat 81 is generated by the air source 7 and specified by the flow control device 12. Compressed air adjusted to the flow rate is supplied.
また、 出力ポート 8 2には、 配管 T 2の一端が接続されている。 Further, one end of a pipe T2 is connected to the output port 82.
尚、 図 1 2中、 9 0は、 必要により設けられる、 流量調整ポートを示しており、 流量調整ポート 9 0には、 出力ポート 8 2より出力する、 空気脈動波の圧力を調 整する出力調整弁 9' 1が、 大気との完全な連通状態から遮断状態迄の間で所望の 状態に調整可能に設けられている。 In FIG. 12, reference numeral 90 denotes a flow rate adjustment port provided as necessary.The flow rate adjustment port 90 has an output for adjusting the pressure of the air pulsation wave output from the output port 82. The regulating valve 9'1 is provided so as to be adjusted to a desired state from a state of complete communication with the atmosphere to a state of shutoff.
次に、 この空気脈動波発生装置 8を用いて所望の周期、 振幅及び波形を有する、 正圧の空気脈動波を発生させる動作手順について説明する。 Next, an operation procedure for generating a positive pressure air pulsation wave having a desired cycle, amplitude and waveform using the air pulsation wave generation device 8 will be described.
まず、 滑沢剤粉末 Lの物性に応じて、 滑沢剤粉末 Lを空気に混和するのが容易 な回転カム 8 7を空気脈動波発生装置 8の駆動手段 (図示せず) の回転軸 m aに 取り付ける。 First, according to the physical properties of the lubricant powder L, the rotating cam 8 7 that can easily mix the lubricant powder L into the air is connected to the rotating shaft ma of the driving means (not shown) of the air pulsation wave generator 8. Attach to
次に、 空気源 7を駆動し、 流量制御装置 1 2を調整することで、 入力ポート 4 2に所定の流量の圧縮空気を供給する。 Next, by driving the air source 7 and adjusting the flow control device 12, a predetermined flow of compressed air is supplied to the input port 42.
また、 駆動手段 (図示せず) を駆動することで、 回転カム 8 7を所定の回転速 度で回転させる。 Further, by driving a driving means (not shown), the rotating cam 87 is rotated at a predetermined rotation speed.
また、 必要により、 出力調整弁 9 1を調整することで、 出力ポート 8 2より出 力される空気脈動波の圧力を調整する。 If necessary, adjust the output adjustment valve 91 to output from the output port 82. Adjust the pressure of the pulsating air pulsation.
回転カム 8 7を所定の回転速度で回転させると、 弁体 8 6を回転カム 8 7に設 けられた凹凸パターンに従って上下する。 これにより、 弁座ヽ 8' 3を、 例えば、 回 転カム 8 7に設けられた凹凸パターンに従って、 全閉、 半開、 全開等に制御する ことで所望の波形の空気脈動波を出力ポート 8 2から出力する。 When the rotary cam 87 is rotated at a predetermined rotation speed, the valve element 86 moves up and down in accordance with the concavo-convex pattern provided on the rotary cam 87. Thus, by controlling the valve seat '8 ′ 3 to be fully closed, half open, fully open, or the like in accordance with, for example, a concavo-convex pattern provided on the rotary cam 87, an air pulsation wave having a desired waveform is output port 82 Output from
尚、 この空気脈動波発生装置 8では、 出力ポート 8 2から出力する空気脈動波 の周期を所望の周期にするには、 駆動手段 (図示せず) を制御して、 回転カム 8 7の回転速度を変えればよい。 また、 出力ポート 8 2から出力する空気脈動波の 振幅を所望の振幅にするには、 空気源 7、 流量制御装置 1 2及び Z又は出力調整 弁 9 1を適宜調整すればよい。 In this air pulsation wave generator 8, in order to set the cycle of the air pulsation wave output from the output port 82 to a desired cycle, the driving means (not shown) is controlled to rotate the rotating cam 87. Just change the speed. In addition, in order to make the amplitude of the air pulsation wave output from the output port 82 to a desired amplitude, the air source 7, the flow control devices 12 and Z, or the output adjustment valve 91 may be adjusted as appropriate.
次に、 この外部滑沢式打錠機 1を用いて、 錠剤 tを連続打錠する方法について 説明する。 Next, a method of continuously tableting the tablet t using the external lubricating tableting machine 1 will be described.
錠剤 tを連続打錠する際には、 まず、 口一タリ型打錠機 2を駆動して、 回転テ 一ブル 2 1、 及び、 複数の上杵 2 3 · · ·、 及び、 複数の下杵 2 4 · · ·を所定 の回転速度で回転させる。 When the tablet t is continuously tableted, first, the tablet-type tableting machine 2 is driven to rotate the rotary table 21 and a plurality of upper punches 23 and a plurality of lower punches. Rotate the pestle 24 at a specified speed.
以上により、 上杵用の粉体材料の塗布装置 3の上杵収容溝 3 1内には、 複数の 上杵 2 3 · · ·が、 順次、 送り込まれる。 As described above, a plurality of upper punches 23 are sequentially fed into the upper punch receiving groove 31 of the powder material application device 3 for the upper punch.
また、 回転テーブル 2 1の回転により、 下杵用の粉体材料の塗布装置 4の下方 の位置には、 複数の曰 2 2 · 'の各々が、 また、 複数の曰 2 2 · · 'の各々に対 応する、 複数の下杵 2 4 · · 'の各々が、 順次、 送り込まれる。 In addition, due to the rotation of the rotary table 21, each of a plurality of statements 2 2 ′ and a plurality of statements 2 2 Each of the plurality of lower punches 24,..., Corresponding to each, is sequentially fed.
また、 空気源 7を駆動させるとともに、 演算装置 (コントローラ) 1 0に各種 デ一夕を入力し、 流量制御弁 v l、 v 2、 流量制御装置 1 2、 空気脈動波発生装 置 8の駆動源 mを適宜調整して、 正圧の空気脈動波を、 配管 T 2内に発生させる。 この 「正圧の空気脈動波」 は、 その振動の山と谷とがともに、 配管 T 2外の大 気圧より高い圧で、 一定の周波数で脈動する空気の波、 又は、 その振動の山が、 配管 T 2外の大気圧より高い圧で、 且つ、 その振動の谷が、 配管 T 2外の大気圧 に概ね等しい圧で、 一定の周波数で脈動する空気の波をいう。 In addition, while driving the air source 7, various data are input to the arithmetic unit (controller) 10 to drive the flow control valves vl and v 2, the flow control device 12, and the air pulsation wave generator 8. By adjusting m as appropriate, a positive pressure air pulsation wave is generated in the pipe T2. This “pulsating air pulsation wave” is a wave of air that pulsates at a constant frequency at a pressure higher than the atmospheric pressure outside the pipe T 2, An air wave that pulsates at a constant frequency at a pressure higher than the atmospheric pressure outside the pipe T2 and at a pressure whose vibration valley is approximately equal to the atmospheric pressure outside the pipe T2.
また、 第 1の吸引手段 1 1を駆動させる。 Further, the first suction means 11 is driven.
また、 第 2の吸引手段 (図示せず。 ) を駆動させる。 第 1の吸引手段 1 1を駆動させると、 上杵用の粉体材料の塗布装置 3のスリッ ト部 3 2の全領域の上側に、 万遍なく、 下方より上方に向かう気流が発生する。 また、 空気脈動波発生装置 8を駆動して、 配管 T 2内に、 正 、-圧の空気脈動波を 発生させると、 空気脈動波発生装置 8により発生させた、 正圧の空気脈動波に対 応して、 粉体材料の吐出装置 (定量フィーダ) 5の弾性膜体 5 4の孔部 (スリヅ ト) 5 4 aが、 閉じ Λ 閉じを繰り返し、 開閉する。 Further, the second suction means (not shown) is driven. When the first suction means 11 is driven, an airflow is generated uniformly from above to below from above the entire area of the slit portion 32 of the powder material applying device 3 for the upper punch. Also, when the air pulsation wave generator 8 is driven to generate positive and negative pressure air pulsation waves in the pipe T2, the air pulsation wave generator 8 generates the positive pressure air pulsation wave. Correspondingly, the hole (slit) 54a of the elastic film 54 of the powder material discharge device (quantitative feeder) 5 repeatedly closes and closes and opens and closes.
弾性膜体 5 4の孔部 (スリット) 5 4 aが開いた時に、 分散室 5 5内に落下し た、 滑沢剤粉末 Lは、 分散室 5 5内で、 旋回流になっている正圧の空気脈動波に 混和して、 分散し、 流動化する。 When the hole (slit) 54 a of the elastic membrane 54 opens, the lubricant powder L that has fallen into the dispersion chamber 55 becomes a swirling flow in the dispersion chamber 55. It mixes with pressure pulsating air, disperses and fluidizes.
そして、 滑沢剤粉末 Lは、 所定の粒径にされると、 分散室 5 5に設けられた排 出口 5 5 bより配管 T 3及び配管 T 3 aを介して、 上杵用の粉体材料の塗布装置 3の粉 料導入口 3 3に送り込まれ、 粉体材料導入口 3 3から送り込まれた滑 沢剤粉末 Lは、 スリット部 3 2から放出される。 When the lubricant powder L has a predetermined particle size, the powder for the upper punch is discharged from the discharge outlet 55b provided in the dispersion chamber 55 through the pipe T3 and the pipe T3a. The lubricant powder L sent to the powder inlet 33 of the material application device 3 and sent from the powder inlet 33 is discharged from the slit 32.
このスリット部 3 2の上方には、 上述したように、 スリット部 3 2の形状と概 ね同じ形状であって、 スリヅト部 3 2の領域を覆う大きさの相似形の吸引口 T 4 aを有する第 1の吸引手段 1 1を駆動させているので、 スリット部 3 2の全領域 の上側に、 万遍なく、 下方より上方に向かう気流が発生している。 Above the slit portion 32, as described above, a suction port T4a having a shape substantially similar to the shape of the slit portion 32 and having a size that covers the area of the slit portion 32 is provided. Since the first suction means 11 is driven, an airflow is generated uniformly above the entire area of the slit portion 32 and directed upward from below.
これにより、 滑沢剤粉末 Lは、 スリット部 3 2の全領域から、 万遍なく、 下方 より上方に向かって、 吸引口 T 4 a方向へ移動する。 As a result, the lubricant powder L moves from the entire area of the slit portion 32 uniformly from the lower side to the upper side in the suction port T4a direction.
また、 上杵用の滑沢剤噴霧ポイント P l aに設置された、 上杵用の粉体材料の 塗布装置 3の上杵収容溝 3 1内には、 上杵 2 3 · · ·が、 順次、 通される。 In addition, in the upper punch receiving groove 3 1, which is located at the upper punch lubricant spraying point P la, and in the upper punch receiving groove 3 1, the upper punch 2 3. , Is passed.
このとき、 上杵収容溝 3 1内を通される上杵 2 3の下面 S 2 3には、 上杵 2 3 が、 スリット部 3 2の起端部 e sから終端部 e eまで移動する間に、 万遍なく、 下方より上方に向かってくる滑沢剤粉末 Lが、 下面に概ね垂直方向に衝突し続け ることになる。 At this time, on the lower surface S 23 of the upper punch 23 passed through the upper punch receiving groove 3 1, the upper punch 23 moves while moving from the starting end es of the slit portion 32 to the terminal end ee. However, the lubricant powder L coming from above to below from all over will continue to collide with the lower surface in a substantially vertical direction.
このようにして、 重力の関係で付着し難い、 上杵 2 3の下面 S 2 3へも、 滑沢 剤粉末 Lが均一に塗布されることとなる。 In this way, the lubricant powder L is evenly applied to the lower surface S 23 of the upper punch 23, which is difficult to adhere due to gravity.
また、 分散室 5 5に設けられた排出口 5 5わより、 空気脈動波の気流に混和し、 分散した滑沢剤粉末 Lは、 配管 T 3及び配管 T 3 bを介して、 下杵用の滑沢剤噴 霧ボイント P 1 bに設置された、 下杵用の粉体材料の塗布装置 4の粉体材料導入 口 e 1に送り込まれ、 粉体材料導入口 e 1から送り込まれた滑沢剤粉末 Lは、 そ の後、 貫通孔 h 1を通って、 貫通孔 h 1の排出口 e 2より、 下杵用の粉体材料の 塗布装置 4の下方に位置している、 曰 2 2内に所定の位置まで挿入された下杵 2 4の上面 S 2 4に、 一気に、 吹き付けられる。 Further, the lubricant powder L mixed with and dispersed in the air pulsating wave air stream from the discharge port 55 provided in the dispersion chamber 55 is supplied to the lower punch through the pipe T3 and the pipe T3b. Lubricant jet Lubricant powder L sent to the powder material inlet e1 of the powder material application device 4 for the lower punch installed in the fog point P 1 b and sent from the powder material inlet e1 is After that, it passes through the through-hole h1 and is located below the powder material application device 4 for the lower punch from the outlet e2 of the through-hole h1. It is sprayed at a stretch onto the upper surface S24 of the lower punch 24 inserted to the position.
この時、 下杵 2 4の上面 S 2 4の中心部から、 曰 2 2の内周壁面 S 2 2方向に 広がるような気流が発生するので、 臼 2 2の内周壁面 S 2 2にも、 滑沢剤粉末 L が付着する。 At this time, an air flow is generated from the center of the upper surface S 24 of the lower punch 24, which spreads in the direction of the inner peripheral wall S 22 of 22, so that the inner peripheral wall S 22 of the mortar 22 also The lubricant powder L adheres.
次に、 下杵 2 4の上面 S 2 4や、 曰 2 2の内周壁面 S 2 2に、 付着したり、 堆 積したりした余分な滑沢剤粉末 Lは、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5より吸引される。 その結果、 下杵 2 4の上面 S 2 4や曰 2 2の内周壁面 S 2 2 に、 粉体材料が均一に塗布される。 Next, the excess lubricant powder L adhered or deposited on the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the second punch 22 is supplied to the second suction means ( It is sucked through the suction port h5 (not shown). As a result, the powder material is uniformly applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 22.
その後、 成形材料充填ポイント P 2において、 フィードシユウ 2 5より成形材 料 (顆粒) Mが、 下杵 2 4が所定の位置まで挿入された曰 2 2内に充填される。 次に、 スクレーパ' 2 6により、 すり切りがされ、 曰 2 2内に充填した成形材料 (顆粒) Mの量が所定の量に調整される。 After that, at the molding material filling point P2, the molding material (granules) M is fed from the feedstock 25 into the space 22 into which the lower punch 24 has been inserted to a predetermined position. Next, the scraper '26 is used for grinding, and the amount of the molding material (granules) M filled in the scraper 22 is adjusted to a predetermined amount.
次いで、 スクレーバ 2 6により、 すり切りがされ、 所定量の成形材料 (顆粒) Mが充填された曰 2 2は、 回転テーブル 2 1の回転に伴って、 予備圧縮ポイント P 3に送られ、 ここで、 予圧ロール 2 7、 2 7により、 組となる上杵 2 3及び下 杵 2 4により予備圧縮がされた後、 本圧縮ポイント P 4に送られ、 本圧ロール 2 8、 2 8により、 組となる上杵 2 3及び下杵 2 4により、 所定の打錠圧により圧 縮成形され錠剤 tにされる。 Next, the scraper 26 is ground and filled with a predetermined amount of the molding material (granules) M. The scrap 22 is sent to the pre-compression point P 3 with the rotation of the rotary table 21, where After being pre-compressed by a pair of upper punches 23 and lower punches 24 by the preload rolls 27, 27, they are sent to the final compression point P4, where they are assembled by the main pressure rolls 28, 28. The upper punch 23 and the lower punch 24 are compressed by a predetermined tableting pressure into tablets t.
本圧縮ボイント P 4において圧縮成形されることにより製造された錠剤 tは、 順次、 錠剤排出ボイント P 5に送られ、 錠剤排出ボイント P 5において、 臼 2 2 内を下杵 2 4が上方に移動することにより、 臼 2 2外へと排出され、 案内板 2 9 により所定の場所に取り出されるようになつている。 The tablets t produced by compression molding at the compression point P 4 are sequentially sent to the tablet discharge point P 5, where the lower punch 24 moves upward in the die 22 at the tablet discharge point P 5. As a result, it is discharged out of the mortar 22 and is taken out to a predetermined place by the guide plate 29.
その後、 曰 2 2、 上杵 2 3及び下杵 2 4は、 吸引手段 (図示せず。 ) 等により、 順次、 各々の表面が清浄された後、 再び、 滑沢剤噴霧ポイント P 1に送られ、 次 の打錠工程に備えるようになつている。 この外部滑沢式打錠機 1では、 以上のような工程を連続して行うことにより、 錠剤 Tを連続的に製造するようになっている。 After that, the surface 22 of the upper punch 23, the upper punch 23 and the lower punch 24 are sequentially cleaned by suction means (not shown) or the like, and then sent to the lubricant spraying point P1 again. It is prepared for the next tableting process. In the external lubricating tablet press 1, the tablet T is continuously produced by continuously performing the above-described steps.
この外部割沢式打錠機 1では、 口一夕リー型打錠機 2の複数の臼 2 2 · · 'の 各々の内周壁面 S 2 2 · · ·、 上杵 2 3 · · ·の各々の下面 S 2 3 · · ·、 及び、 下杵 2 4 · · 'の各々の上面 S 2 4 · · ·に、 均一に、 滑沢剤粉末 Lを塗布でき るので、 錠剤 tを連続打錠する際に、 上杵 2 3 · · ·、 下杵 2 4 · · ·、 及び曰 2 2 · · ·に、 ギシヅキを生じることなく、 且つ、 打錠障害 (ラミネ一ティング、 キヤヅビング、 スティヅキング等) を生じることなく、 連続打錠が可能になる。 これにより、 敢えて、 成形材料 M中には、 滑沢剤粉末 Lを添加しなくても、 生 産ベースで、 錠剤の製造が可能になる。 In the external split-type tableting machine 1, the inner peripheral wall S2 2 of each of the plurality of dies 2 2 Lubricant powder L can be uniformly applied to each lower surface S 2 3 ··· and lower punch 2 4 ··· 's respective upper surface S 2 4 ··· When locking, the upper punch 2 3 · · · the lower punch 2 4 · · · and 22 · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · without causing squeaks on tableting and preventing tableting (laminating, caving, sticking etc.) ) Continuous tableting becomes possible without producing This makes it possible to produce tablets on a production basis without the need to add the lubricant powder L into the molding material M.
また、 粉# ^料として、 滑沢剤粉末 Lの代わりに、 表面改質剤を用いた場合に は、 上杵 2 3 · · ·の各々の下面 S 2 3 · · ·、 下杵 2 4 · · ·の各々の上面 S 2 4 · · ■、 及び、 曰 2 2 · · 'の各々の内周壁面 S 2 2の各々に、 表面改質剤 を均一に塗布できる。 したがって、 この外部割沢式打錠機 1を用いれば、 錠剤 t の表面に表面改質剤が均一に塗布された錠剤を製造できるようになる。 When a surface modifier is used instead of the lubricant powder L as the powder # ^, the lower surface of each of the upper punch 23 and the lower punch 24 The surface modifier can be uniformly applied to each of the inner peripheral wall surfaces S22 of the respective top surfaces S2 4. Therefore, the use of the external split type tableting machine 1 makes it possible to produce a tablet in which the surface modifier is uniformly applied to the surface of the tablet t.
更に、 上述したように、 上杵用の粉体材料の塗布装置 3のスリット部 3 2の幅 W 3 2を、 錠剤に形成する割線や刻印の領域の幅に概ね一致するようにすれば、 上杵収容溝 3 1内を移動してくる、 上杵 2 3 · · ·の各々の下面 S 2 3 · · ·の、 割線や刻印を形成する部分、 即ち、 複雑な凸部が形成されている部分を中心にし て、 上杵 2 3 · · ·の各々の下面 S 2 3 · · ·に、 十分に且つ均一に、 粉体材料 が塗布される。 Further, as described above, if the width W32 of the slit portion 32 of the powder material application device 3 for the upper punch is made to substantially match the width of the area of the score line or the mark formed on the tablet, The lower surface S 2 3 of each of the upper punches 2 3 moving in the upper punch receiving groove 3 1 forms a parting line or a mark, that is, a complex convex portion is formed. The powder material is sufficiently and uniformly applied to the lower surface S 23 of each of the upper punches 23 around the part where the upper punch is located.
これにより、 粉体材料として、 滑沢剤を用いた場合には、 錠剤の、 割線や刻印 を設けた部分、 即ち、 複雑な凹凸が形成されている部分で、 ラミネーティング、 キヤッビング、 スティヅキングを生じること無く、 錠剤を製造することができる。 したがって、 この装置 3を用いれば、 従来は、 生産ベースで製造することが難 しかった、 割線や刻印を設けた外部滑沢錠剤を、 生産ベースで製造することがで きるようになる。 As a result, when a lubricant is used as the powder material, laminating, cabbing, and sticking occur in the portion of the tablet provided with the score lines or inscriptions, that is, in the portion having complicated irregularities. Tablets can be manufactured without any need. Therefore, if this device 3 is used, an external lubricating tablet provided with a score line or a stamp can be manufactured on a production basis, which has conventionally been difficult to produce on a production basis.
また、 以上の説明では、 粉体材料として、 滑沢剤粉末 Lを用いた例について説 明したが、 粉 料として、 滑沢剤粉末 Lに代えて、 表面改質剤粉末を用いた場 合には、 従来、 製造するのが困難であった、 割線や刻印が設けられた部分にも、 均一に、 表面改質剤が塗布された錠剤を製造できるようになる。 Further, in the above description, an example was described in which the lubricant powder L was used as the powder material. However, in the case where the surface modifier powder was used instead of the lubricant powder L as the powder material. In this case, it becomes possible to manufacture a tablet uniformly coated with a surface-modifying agent even in a part where a score line or a mark is provided, which has been difficult to manufacture conventionally.
また、 この外部滑沢式打錠機 1では、 下杵用の粉体材料の塗布装置 4に、 第 2 の吸引手段 (図示せず。 ) を設け、 錠剤 tを製造する間、 第 2の吸引手段 (図示 せず。 ) を駆動させて、 スリツト部 h 5により、 下杵 2 4 · · 'の各々の下面 S Further, in this external lubricating tableting machine 1, a second suction means (not shown) is provided in the powder material application device 4 for the lower punch, and during the production of the tablet t, the second suction means is provided. The suction means (not shown) is driven, and the lower surface S of each of the lower punches 24.
2 4 · · ·、 及び、 曰 2 2 · · ·の各々の内周壁面 S 2 2 · · ·に、 余分に付着 している粉体材料、 及び/又は、 回転テーブル 2 1上の余分な粉体材料を除去す るようにしている。 And powder material adhering extra to the inner peripheral wall S 2 2 of each of 2 4 We try to remove the powder material.
したがって、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5より下流位置にある、 成形材料充填ボイント P 2の位置で、 下杵 2 4及び臼 2 2により形成される空間 内に、 順次、 成形材料 Mを充填する工程において、 下杵 2 4及び臼 2 2に余分に 付着している粉体材料、 及び/又は、 回転テーブル 2 1上の余分な粉# ^料が、 成形材料中に、 混入することを防ぐことができる。 Therefore, at the position of the molding material filling point P 2 downstream of the suction port h 5 of the second suction means (not shown), the space formed by the lower punch 24 and the die 22 is In the step of sequentially filling the molding material M, the powder material excessively adhering to the lower punch 24 and the die 22 and / or the excess powder material on the rotary table 21 are added to the molding material. It can be prevented from being mixed in.
これにより、 内部に、 滑沢剤粉末! ^や表面改質剤を含むことの無い、 外部滑沢 錠剤を、 効率よく製造することもできる。 This makes it possible to efficiently produce an external lubricating tablet that does not contain a lubricant powder or a surface modifier therein.
図 1 3は、 本発明に係る下杵用の粉体材料の塗布装置の他の例を概略的に示す 平面図である。 FIG. 13 is a plan view schematically showing another example of a powder material applying device for a lower punch according to the present invention.
この下杵用の粉体材料の塗布装置 4 Aは、 以下の構成を除けば、 下杵用の粉体 材料の塗布装置 4と同様であるので、 説明を容易とするため、 相当する部材装置 には、 相当する参照符号を付して、 その説明を省略する。 The powder material application device 4A for the lower punch is the same as the powder material application device 4 for the lower punch except for the following configuration. Are given the corresponding reference numerals, and their description is omitted.
この下杵用の粉体材料の塗布装置 4 Aは、 以下の点で、 下杵用の粉体材料の塗 布装置 4と異なっている。 The powder material coating device 4A for the lower punch differs from the powder material coating device 4 for the lower punch in the following points.
即ち、 この下杵用の粉体材料の塗布装置 4 Aには、 回転テーブル 2 1に対向す る表面 S 4 aの、 排出口 e 2の前段部に、 スリット状の成形材料吸引口 h 6 aを 有する第 3の吸引手段 (図示せず。 ) を、 更に備える。 That is, in the powder material application device 4A for the lower punch, a slit-shaped molding material suction port h6 is provided at the front stage of the discharge port e2 on the surface S4a facing the rotary table 21. A third suction means (not shown) having a is further provided.
この第 3の吸引手段 (図示せず。 ) の成形材料吸引口 h 6 aは、 複数の下杵 2 The molding material suction port h 6 a of the third suction means (not shown) is provided with a plurality of lower punches 2.
3 · · ·の上面 S 2 3 · · ·、 複数の曰 2 2 · · ·の各々の内周壁面 S 2 2 · · •及び複数の臼 2 2 · · ·の周辺に付着している成形材料 Mを、 順次、 除去する ために設けられているものであり、 複数の曰 2 2 · · 'の回転軌道 O rに概ね直 交するように、 且つ、 複数の曰 22 · · 'の各々の直径と概ね一致する幅か、 そ れよりやや大きい幅を有している。 The upper surface of 3 · · · S 2 3 · · ·, a plurality of said 2 2 · · · each inner peripheral wall S 2 2 · · · and a plurality of dies 2 2 · · · formed around the periphery of 2 · · · · It is provided for sequentially removing the material M, and is substantially directly on a plurality of rotation orbits of 22 2. It has a width that is approximately the same as, or slightly larger than, the diameter of each of a plurality of said lines.
この下杵用の粉体材料の塗布装置 4 Aでは、 滑沢剤粉末 Lを排出する排出口 e 2の前段部に、 成形材料吸引口 h 6 aを有する第 3の吸引手段 (図示せず。 ) を 設け、 滑沢剤粉末 Lを、 曰 22 · · 'の各々噴霧する前に、 曰 22 · · 'の各々 の内周壁面 S 22 · · ·及び下杵 24 · · ·の各々の上面 S 24 · · ·を清浄し ているので、 前工程で使用した成形材料 Mや滑沢剤粉末 が、 次工程で製造され る錠剤 t · · '中に混入することがないので、 錠剤 t · · 'を連続的に製造して も、 錠剤 t · · '間で、 滑沢剤粉末 Lの使用量等に不均一を生じない。 これによ り、 同じ規格の錠剤 t · · 'を連続的に製造できる。 In the powder material application device 4A for the lower punch, a third suction means (not shown) having a molding material suction port h6a is provided at the front stage of the discharge port e2 for discharging the lubricant powder L. ), And before spraying each of the lubricant powders L, the respective inner peripheral wall surfaces S22 and the lower punches 24 of the said 22. Since the top surface S24 is clean, the molding material M and lubricant powder used in the previous process do not mix into the tablets t Even if tablets are manufactured continuously, there is no unevenness in the amount of lubricant powder L used between tablets t As a result, tablets of the same standard can be manufactured continuously.
尚、 この下杵用の粉体材料の塗布装置 4 Aでも、 図 13 (c) に示すように、 排出口 e 2と、 吸引口 h 5との間の距離 L (e 2-h5) を、 少なくとも、 臼 2 2の直径 D 22に比べ、 長くなるようにしている。 In addition, even in the powder material application device 4A for the lower punch, as shown in FIG. 13 (c), the distance L (e2-h5) between the discharge port e2 and the suction port h5 is determined. However, at least the mortar 22 is longer than the diameter D22.
即ち、 この下杵用の粉体材料の塗布装置 4 Aでも、 第 2の吸引手段 (図示せず。 ) の吸引口を、 少なくとも、 排出口 e 2が設けられている位置から、 回転テーブル 21に設けられる、 複数の臼 22 · · ·の各々の直径 D 22より、 離れた位置に 設けている (L (e 2-h5) >D 22) 。 That is, in the powder material application device 4A for the lower punch as well, the suction port of the second suction means (not shown) is moved at least from the position where the discharge port e2 is provided to the rotary table 21. Provided at a distance from the diameter D22 of each of the plurality of dies 22 (L (e2-h5)> D22).
従って、 この下杵用の粉体材料の塗布装置 4 Aでも、 下杵 24の上面 S 24及 び曰 22の内周壁面 S 22に塗布された粉体材料 (この例では、 滑沢剤粉末 L) の中、 下杵 24の上面 S 24及び曰 22の内周壁面 S 22にとつて余分な粉体材 料 (この例では、 滑沢剤粉末 L) を、 臼 22内に所定の位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける場 所 (即ち、 排出口 e 2) とは、 曰 22を会して、 導通しない場所で、 吸引除去す るようにしているので、 臼 22内に所定の位置まで揷入された下杵 24の上面 S 24に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける条件に影響を与 えることなく、 下杵 24の上面 S 24及び臼 22の内周壁面 S 22に塗布された 粉体材料 (この例では、 滑沢剤粉末 L) の中、 下杵 24の上面 S 24及び臼 22 の内周壁面 S 22にとつて余分な粉体材料 (この例では、 滑沢剤粉末 L) を、 吸 引除去することができる。 更に、 この下杵用の粉体材料の塗布装置 4 Aでは、 図 13 (c) に示すように、 排出口 e 2と、 吸引口 h6 aとの間の距離 L (e2-h6 a) を、 少なくとも、 曰 22の直径 D 22に比べ、 長くなるようにしている。 Therefore, the powder material applying apparatus 4A for the lower punch also applies the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 (in this example, the lubricant powder L), extra powder material (in this example, lubricant powder L) is placed in the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 in a predetermined position in the die 22. Where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted up to (ie, the discharge port e 2) In this case, the condition is such that the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted into the die 22 to a predetermined position. Of the powder material (in this example, lubricant powder L) applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the die 22 without giving the upper surface of the lower punch 24. Excess powder material (in this example, lubricant powder L) can be sucked and removed from the inner peripheral wall S22 of S24 and the mortar 22. Further, in the powder material application device 4A for the lower punch, as shown in FIG. 13 (c), the distance L (e2-h6 a) between the discharge port e2 and the suction port h6a is changed. At least, it is longer than the diameter D22 of 22.
即ち、 この下杵用の粉体材料の塗布装置 4 Aでは、 第 3の吸引手段 (図示せず。 ) の吸引口 h 6 aを、 少なくとも、 排出口 e 2が設けられている位置から、 回転テ 一ブル 21に設けられる、 複数の曰 22 · · ·の各々の直径 D22より、 離れた 位置に設けている (L (e 2-h6) >D 22) 。 That is, in the powder material application device 4A for the lower punch, the suction port h6a of the third suction means (not shown) is moved at least from the position where the discharge port e2 is provided. The rotating table 21 is provided at a position apart from the diameter D22 of each of a plurality of said 22... (L (e2-h6)> D22).
従って、 この下杵用の粉体材料の塗布装置 4 Aでは、 下杵 24の上面 S 24及 び曰 22の内周壁面 S 22に粉体材料 (この例では、 滑沢剤粉末 L) を塗布する 前に、 たとえ、 下杵 24の上面 S 24及び曰 22の内周壁面 S 22に付着してい たとしても、 不要な成形材料や粉体材料 (この例では、 滑沢剤粉末 L) を、 曰 2 2内に所定の位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に 分散した粉 料を直接吹き付ける場所 (即ち、 排出口 e 2) とは、 臼 22を介 して、 導通しない場所で、 吸引除去するようにしているので、 曰 22内に所定の 位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に分散した粉体 材料を直接吹き付ける条件に影響を与えることなく、 回転テーブル 21の表面、 下杵 24の上面 S 24及び臼 22の内周壁面 S 22に付着している、 不要な成形 材料や粉体材料 (この例では、 滑沢剤粉末 L) を、 吸引除去することができる。 また、 図 14は、 本発明に係る外部滑沢式打錠機の他の一例を概略的に示す全 体構成図である。 - また、 図 15は、 図 14に示す外部滑沢式打錠機を構成する口一タリ型打錠機 の回転テーブル、 上杵用の粉体材料の塗布装置及び下杵用の粉体材料の塗布装置 の配置を概略的に示す平面図であり、 また、 図 16は、 図 15に示す回転テープ ルを、 成形材料充填ポィントと滑沢剤塗布ボイントとの間で切断して展開した模 式的な展開図を示している。 Accordingly, in the powder material applying device 4A for the lower punch, the powder material (in this example, lubricant powder L) is applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 22. Before application, even if it adheres to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 24, unnecessary molding materials and powder materials (in this example, lubricant powder L) The place where the powder dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S24 of the lower punch 24 inserted to a predetermined position in 22 (that is, the discharge port e2) is a die 22 The powder material dispersed in the air current of the air pulsating wave is placed on the upper surface S 24 of the lower punch 24 inserted to a predetermined position in Without affecting the conditions for directly spraying, the liquid adheres to the surface of the rotary table 21, the upper surface S24 of the lower punch 24, and the inner peripheral wall S22 of the die 22. That (in this example, wax powder L) unwanted molding material and powder material can be sucked and removed. FIG. 14 is a general configuration diagram schematically showing another example of the external lubricating tableting machine according to the present invention. -Fig. 15 shows the rotary table of the one-piece tableting machine that constitutes the external lubricating tableting machine shown in Fig. 14, the powder material application device for the upper punch and the powder material for the lower punch. FIG. 16 is a plan view schematically showing the arrangement of the coating apparatus of FIG. 15, and FIG. 16 is a schematic view in which the rotary table shown in FIG. 15 is cut and developed between a molding material filling point and a lubricant applying point. It shows a schematic development.
この外部滑沢式打錠機 1 Aは、 以下の点を除けば、 図 1に示す外部滑沢式打錠 機 1と同様であるので、 相当する部材装置については、 相当する参照符号を付し て、 その説明を省略する。 This external lubricating tableting machine 1A is the same as the external lubricating tableting machine 1 shown in FIG. 1 except for the following points, and the corresponding components are denoted by the corresponding reference numerals. The description is omitted.
この外部滑沢式打錠機 1 Aは、 以下の点が、 外部滑沢式打錠機 1と異なってい る。 This external lubricating tablet press 1A differs from the external lubricating tablet press 1 in the following points. You.
即ち、 この外部滑沢式打錠機 1 Aでは、 下杵用の粉体材料の塗布装置 4に対し、 回転テーブル 2 1の逆方向の位置ではなく、 回転テーブル 2 1の順方向の位置に、 上杵用の粉体材料の塗布装置 3を設 ( "ている。 That is, in the external lubricating tableting machine 1A, the powder material application device 4 for the lower punch is not positioned in the reverse direction of the rotary table 21 but in the forward direction of the rotary table 21. In addition, a powder material coating device 3 for the upper punch is provided ("").
このように、 上杵用の粉体材料の塗布装置 3は、 下杵用の粉体材料の塗布装置 4に対し、 回転テーブル 2 1の逆方向の位置に設けても、 順方向の位置に設けて もよいので、 本発明に係る外部滑沢式打錠機は、 設計上の自由度が高い。 In this way, the powder material applicator 3 for the upper punch is provided at the position opposite to the rotary table 21 in the forward direction with respect to the powder material applicator 4 for the lower punch. Since it may be provided, the external lubricating tablet press according to the present invention has a high degree of freedom in design.
(発明の実施の形態 2 ) (Embodiment 2)
発明の実施の形態 2では、 上杵用の粉体材料の塗布装置と、 下杵用の粉体材料 の塗布装置とを一体に設けたような、 粉体材料の塗布装置を用いた例について説 明する。 Embodiment 2 of the present invention relates to an example in which a powder material application device is used in which a powder material application device for an upper punch and a powder material application device for a lower punch are integrally provided. explain.
図 1 7は、 そのような粉体材料の塗布装置を備える外部滑沢式打錠機の一例を 概略的に示す全体構成図である。 FIG. 17 is an overall configuration diagram schematically showing an example of an external lubricating tableting machine equipped with such a powder material application device.
尚、 図 1 7に示す外部滑沢式打錠機は、 図 1に示す外部滑沢式打錠機 1とは、 粉体材料の塗布装置以外の部材装置の構成は、 図 1に示す外部滑沢式打錠機 1と 同様であるので、 相当する部材装置には、 相当する参照符号を付して、 その説明 を省略する。 The external lubricating tablet press shown in FIG. 17 is different from the external lubricating tablet press 1 shown in FIG. Since it is the same as that of the lubricating tablet press 1, the corresponding member devices are denoted by the corresponding reference numerals, and description thereof will be omitted.
図 1 8は、 図 1 7に示す外部滑沢式打錠機を構成するロータリ型打錠機の回転 テーブル、 粉体材料の塗布装置の配置を概略的に示す平面図である。 FIG. 18 is a plan view schematically showing an arrangement of a rotary table and a powder material coating device of the rotary tableting machine constituting the external lubricating tableting machine shown in FIG.
また、 図 1 9は、 図 1 7に示す回転テーブルを、 成形材料充填ボイントと滑沢 剤塗布ポィントとの間で切断して展開した模式的な展開図を示している。 FIG. 19 is a schematic developed view in which the rotary table shown in FIG. 17 is cut and developed between a molding material filling point and a lubricant application point.
また、 図 2 0は、 この粉体材料の塗布装置 1 3を概略的に示す平面図である。 また、 図 2 1は、 図 2 0中、 XX I— XX I線に従う概略的な断面図であり、 また、 図 2 2は、 図 2 0中、 XX I I— XX I I線に従う概略的な断面図である。 尚、 図 2 1では、 図面の理解を容易とするために、 図 2 1中に表されている、 2本の上杵 2 3、 2 3の中、 一方の上杵 2 3を想像線で示している。 FIG. 20 is a plan view schematically showing the powder material coating device 13. FIG. 21 is a schematic sectional view taken along the line XXI—XXI in FIG. 20. FIG. 22 is a schematic sectional view taken along the line XXII—XXII in FIG. FIG. In FIG. 21, one of the two upper punches 23, 23 shown in FIG. 21 is represented by an imaginary line to facilitate understanding of the drawing. Is shown.
この粉体材料の塗布装置 1 3は、 上杵用の粉体材料の塗布装置 3と同様な上杵 用の粉体材料の塗布装置 3 Bと、 下杵用の粉体材料の塗布装置 4と同様な下杵用 の粉体材料の塗布装置 4 Bとがー体 (; ϊされたような構成になつている。 より詳しく説明すると、 この粉体材料の塗布装置 1 3は、 回転テーブル 2 1上 の所定の位置に固定的に設けるようにされている。 The powder material coating device 13 is a powder material coating device 3B for the upper punch similar to the powder material coating device 3 for the upper punch 3 and a powder material coating device 4 for the lower punch 4 A powder material application device 4 B for lower punches similar to that described above is configured as shown in FIG. More specifically, the powder material coating device 13 is fixedly provided at a predetermined position on the turntable 21.
そして、 粉体材料の塗布装置 1 3を構成する下杵用の粉体材料の塗布装置 4 B に、 回転テ一ブル 2 1の回転方向とは逆方向の位置に、 上杵用の粉体材料の塗布 装置 3 Bが、 一体的に接続された構造になっている。 Then, the powder material application device 4 B for the lower punch, which constitutes the powder material application device 13, is placed in a position opposite to the rotation direction of the rotating table 21, and the powder for the upper punch is used. The material coating device 3B has a structure that is integrally connected.
尚、 この粉体材料の塗布装置 1 3は、 接続用プレート 1 3 pを備える。 この接 続用プレート 1 3 pは、 粉体材料の塗布装置 1 3への配管を容易とするために設 けられるものであり、 その上面には、 後述する、 粉体材料導入口 e 1、 接続口 e 5、 e 9等が設けられる。 The powder material application device 13 includes a connection plate 13p. The connection plate 13 p is provided for facilitating the piping of the powder material to the applicator 13, and has a powder material inlet e 1, described later, on its upper surface. Connection ports e5 and e9 are provided.
下杵用の粉体材料の塗布装置 4 Bは、 回転テーブル 2 1が、 摺動できるように、 回転テーブルに対向する側の表面 S 4 aが、 滑らかな表面にされている。 In the powder material application device 4B for the lower punch, the surface S4a facing the rotary table is made a smooth surface so that the rotary table 21 can slide.
また、 上杵用の粉体材料の塗布装置 3 Bも、 回転テーブル 2 1が、 摺動できる ように、 回転テーブル 2 1に対向する側の表面 S 3 aが、 滑らかな表面にされて いる。 The powder material application device 3B for the upper punch also has a smooth surface S3a facing the rotary table 21 so that the rotary table 21 can slide. .
下杵用の粉体材料の塗布装置 4 Bは、 その上面 S 4 bに、 空気脈動波の気流に 分散された滑沢剤粉末 Lを送り込む粉体材料導入口 e 1が設けられており、 粉体 材料導入口 e 1に送り込まれた滑沢剤粉末 Lは、 下杵用の粉体材料の塗布装置 4 Bを貫通するように設けられた貫通孔 h iを通って、 回転テーブル 2 1に対向す る側の表面 S 4 aに送られるようになつている。 そして、 貫通孔 h iの回転テ一 ブル 2 1に対向する側の表面側 S 4 aの排出口 e 2より、 正圧の空気脈動波とと も排出された滑沢剤粉末 Lは、 下杵用の粉体材料の塗布装置 4 Bの下方に収容さ れている、 臼 2 2の内周壁面 S 2 2、 及び、 臼 2 2内に所定の深さまで挿入され た下杵 2 4の上面 2 4に吹き付けられるようになつている。 The powder material application device 4B for the lower punch has a powder material inlet e1 on its upper surface S4b for feeding the lubricant powder L dispersed in the air current of the air pulsation wave. The lubricant powder L sent to the powder material inlet e 1 passes through the through-hole hi provided so as to penetrate the powder material application device 4 B for the lower punch, and passes through the rotary table 21. It is sent to the surface S 4 a on the opposite side. The lubricant powder L discharged together with the positive pressure air pulsation wave from the outlet e 2 of the surface S 4 a facing the rotary table 21 of the through-hole hi is supplied to the lower punch. The inner peripheral wall S22 of the mortar 22 and the upper surface of the lower punch 24 inserted into the mortar 22 to a predetermined depth, which are accommodated below the powder material application device 4B for the mortar 22 It can be sprayed on 24.
また、 上杵用の粉体材料の塗布装置 3 Bは、 回転テーブル 2 1に対向する側の 表面 S 3 aから上杵用の粉体材料の塗布装置 3を貫通するように、 且つ、 複数の 上杵の回転軌道に沿うように湾曲した長尺なスリット部 3 2と、 上杵用の粉 料の塗布装置 3 Bの外表面 S 3 b側に設けられ、 スリット部 3 2の領域を含むよ うに、 且つ、 回転移動してくる複数の上杵 2 3 · · ·を収容するために設けられ た上杵収容溝 3 1とを備える。 上杵収容溝 3 1は、 複数の上杵 2 3 · · ·の回転軌道 O rに沿うように湾曲し て設けられている。 Further, the powder material applying device 3B for the upper punch is formed so as to penetrate the powder material applying device 3 for the upper punch from the surface S3a on the side facing the rotary table 21 and A long slit section 32 curved along the rotation path of the upper punch and the outer surface S 3 b side of the powder applicator 3 B for the upper punch are provided on the side of the slit section 32. And an upper punch accommodation groove 31 provided for accommodating a plurality of upper punches 23 rotating in a rotatable manner. The upper punch receiving groove 31 is provided so as to be curved along the rotation path Or of the plurality of upper punches 23.
そして、 上杵収容溝 3 1の幅 W 3 1は、 複数の上杵 2 3 · · 'の各々の外径と. 一致する幅か、 それよりやや大きい幅にされており、 上杵収容溝 3 1に収容され ている、 上杵 2 3の下面 S 2 3は、 スリット部 3 2から供給される滑沢剤粉末 L に曝され易くなつている一方、 上杵収容溝 3 1に収容されている、 上杵 2 3の側 周には、 滑沢剤粉末 Lが付着し難いようにされている。 The width W 3 1 of the upper punch receiving groove 3 1 is equal to or slightly larger than the outer diameter of each of the plurality of upper punches 23. The lower surface S 23 of the upper punch 23 accommodated in the upper punch 23 is easily exposed to the lubricant powder L supplied from the slit portion 32, while being accommodated in the upper punch receiving groove 31. The lubricant powder L is hardly attached to the periphery of the upper punch 23.
以上の、 上杵用の粉体材料の塗布装置 3 B及び下杵用の粉体材料の塗布装置 4 Bの各々の構成は、 上杵用の粉体材料の塗布装置 3及び下杵用の粉体材料の塗布 装置 4の各々の構成と同様であるが、 この粉体材料の塗布装置 1 3では、 この粉 体材料の塗布装置 1 3を構成する下杵用の粉体材料の塗布装置 4 Bの貫通孔 h 1 の回転テーブル 2 1に対向する側の表面 S 4 a側の排出口 e 2から、 空気に混和 された状態で排出された滑沢剤粉末 Lは、 更に、 上杵用の粉体材料の塗布装置 3 Bに設けられたスリット部 3 2に供給されるようになっている。 The configuration of the powder material coating device 3B for the upper punch and the powder material coating device 4B for the lower punch are as described above. The configuration of the powder material coating device 4 is the same as that of the powder material coating device 4. However, the powder material coating device 13 is a powder material coating device for the lower punch, which constitutes the powder material coating device 13. The lubricant powder L discharged in a state of being mixed with air from the surface S 4 a on the side of the through hole h 1 facing the rotary table 21 on the side of the rotary table 21 is further subjected to an upper punch. Is supplied to a slit portion 32 provided in a powder material coating device 3B.
より詳しく説明すると、 この下杵用の粉体材料の塗布装置 4 Aの、 回転テープ ル 2 1に対向する側の表面 S 4 aには、 図 2 1に示すように、 回転テーブル 2 1 の回転方向 (図 2 1中、 回転テーブル 2 1に示されている矢印の方向を参照。 ) と逆方向に、 複数の臼 2 2 · · 'の回転軌道 O rに沿うように湾曲した長溝 D 1 が形成されている。 More specifically, as shown in FIG. 21, the surface S 4 a of the powder material application device 4 A for the lower punch facing the rotary table 21 is provided with a rotary table 21 1 In the direction opposite to the direction of rotation (see the direction of the arrow shown on the turntable 21 in Fig. 21), a long groove D curved along the rotation path Or of the plurality of dies 2 2 1 is formed.
この長溝 D 1の幅は、 複数の曰 2 4 · · ·の各々の直径と同じ幅か、 それより やや大きい幅にされている。 The width of the long groove D1 is the same as or slightly larger than the diameter of each of the plurality of said grooves 24.
また、 この長溝 D 1は、 貫通孔 h 1の排出口 e 2の、 回転テーブル 2 1の回転 方向と逆方向へ、 回転テーブル 2 1に対向する側の表面 S 4 aから少しくぼんだ 形状を有している。 In addition, the long groove D 1 has a shape in which the discharge port e 2 of the through hole h 1 is slightly recessed from the surface S 4 a on the side facing the turn table 21 in a direction opposite to the rotation direction of the turn table 21. Have.
そして、 この長溝 D 1は、 上杵用の粉体材料の塗布装置 3 Bのスリヅト部 3 2 の下方に設けられている長溝 D 2に接続されている。 The long groove D1 is connected to a long groove D2 provided below the slit portion 32 of the powder material applying device 3B for the upper punch.
上杵用の粉体材料の塗布装置 3の長溝 D 2は、 図 2 2に示すように、 上杵用の 粉体材料の塗布装置 3の、 回転テーブル 2 1に対向する側の表面 S 3 aから少し くぼんだ形状を有している。 この粉体材料の塗布装置 1 3では、 下杵用の粉体材料の塗布装置 4 Aの長溝 D 1を、 上杵用の粉体材料の塗布装置 3 Bの長溝 D 2に接続し、 下杵用の粉体材料 の塗布装置 4 Bの貫通孔 h iの排出口 e 2より、 空気とともに、 下杵用の粉 ^" As shown in FIG. 22, the long groove D 2 of the powder material applicator 3 for the upper punch has a surface S 3 on the side of the powder material applicator 3 for the upper punch facing the rotary table 21. It has a slightly concave shape from a. In the powder material application device 13, the long groove D 1 of the powder material application device 4 A for the lower punch is connected to the long groove D 2 of the powder material application device 3 B for the upper punch. Powder material applicator for punches 4 From the egress e2 of the through-hole hi of B, together with air, powder for lower punches ^ "
ヽ' ヽ '
料の塗布装置 4 Bの下方に位置する曰 2 2内に所定の位置まで挿入された下杵 2 4の上面 S 2 4に吹き付けられた滑沢剤粉末 Lは、 長溝 D 1を通って、 長溝 D 2 へ移動し、 スリット部 3 2から排出されるようになっている。 The lubricant powder L sprayed on the upper surface S 24 of the lower punch 24 inserted to a predetermined position in the device 22 located below the material application device 4 B passes through the long groove D 1, It moves to the long groove D 2 and is discharged from the slit portion 32.
即ち、 この粉体材料の塗布装置 1 3では、 下杵用の粉体材料の塗布装置 4 Bの 貫通孔 h iの排出口 e 2より、 空気とともに、 下杵用の粉体材料の塗布装置 4の 下方に収容されている、 曰 2 2内に所定の深さまで挿入された下杵 2 4の上面 S 2 4に吹き付けられた滑沢剤粉末 Lは、 下杵 2 4の上面 S 2 4に付着する。 In other words, in the powder material coating device 13, the lower punch material coating device 4 B with the air is discharged from the outlet e 2 of the through hole hi of the lower punch powder material coating device 4 B. The lubricant powder L sprayed on the upper surface S 24 of the lower punch 24 inserted to a predetermined depth into the upper surface of the lower punch 24 is stored on the upper surface S 24 of the lower punch 24. Adhere to.
そして、 下杵 2 4の上面 S 2 4に余分に堆積している滑沢剤粉末 Lは、 曰 2 2 の内周壁面 S 2 2に吹き付けられ、 臼 2 2の内周壁面 S 2 2に付着する。 Then, the lubricant powder L, which is excessively deposited on the upper surface S 24 of the lower punch 24, is sprayed on the inner peripheral wall surface S 22 of 22, and the inner peripheral wall surface S 22 of the mortar 22. Adhere to.
次に、 この外部滑沢式打錠機 1 Bを用いて、 錠剤 tを連続打錠する方法につい て説明する。 Next, a method of continuously tableting tablets t using this external lubricating tableting machine 1B will be described.
錠剤 tを連続打錠する際には、 まず、 口一タリ型打錠機 2を駆動して、 回転テ —ブル 2 1、 及び、 複数の上杵 2 3 · · ·、 及び、 複数の下杵 2 4 · · ·を所定 の回転速度で回転させる。 When continuously compressing tablets t, first, the one-shot tablet press 2 is driven to rotate the rotary table 21 and a plurality of upper punches 23 and a plurality of lower punches. Rotate the pestle 24 at a specified speed.
また、 空気源 7を駆動させるとともに、 演算装置 (コントローラ) 1 0に各種 データを入力し、 流量制御弁 v l、 v 2、 流量制御装置 1 2、 空気脈動波発生装 置 8の駆動源 mを適宜調整して、 正圧の空気脈動波を、 配管 T 2内に発生させる。 また、 第 1の吸引手段 1 1を駆動させる。 In addition to driving the air source 7, various data are input to the arithmetic unit (controller) 10, and the drive source m of the flow control valves vl and v 2, the flow control device 12, and the air pulsation wave generator 8 is With appropriate adjustment, a positive pressure air pulsation wave is generated in the pipe T2. Further, the first suction means 11 is driven.
また、 第 2の吸引手段 (図示せず。 ) を駆動させる。 Further, the second suction means (not shown) is driven.
第 1の吸引手段 1 1を駆動させると、 粉体材料の塗布装置 1 3を構成する上杵 用の粉体材料の塗布装置 3 Bのスリット部 3 2の全領域の上側に、 万遍なく、 下 方より上方に向かう気流が発生する。 When the first suction means 11 is driven, the powder material application device 3 for the upper punch, which constitutes the powder material application device 13, is uniformly distributed over the entire area of the slit portion 3 2 of the B 3 B. An airflow is generated that goes upward from below.
また、 空気脈動波発生装置 8を駆動して、 配管 T 2内に、 正圧の空気脈動波を 発生させると、 空気脈動波発生装置 8により発生させた、 正圧の空気脈動波に対 応して、 粉 料の吐出装置 (定量フィーダ) 5の弾性膜体 5 4の孔部 (スリツ ト) 5 4 aが開閉する。 弾性膜体 5 4の孔部 (スリット) 5 4 aが開いた時に、 分散室 5 5内に落下し た、 滑沢剤粉末 Lは、 分散室 5 5内で、 旋回流になっている正圧の空気脈動波に 混和して、 分散し、 流動化する。 When the air pulsation wave generator 8 is driven to generate a positive pressure air pulsation wave in the pipe T2, the air pulsation wave generator 8 responds to the positive pressure air pulsation wave. Then, the hole (slit) 54a of the elastic film 54 of the powder discharger (quantitative feeder) 5 opens and closes. When the hole (slit) 54 a of the elastic membrane 54 opens, the lubricant powder L that has fallen into the dispersion chamber 55 becomes a swirling flow in the dispersion chamber 55. It mixes with pressure pulsating air, disperses and fluidizes.
そして、 滑沢剤粉末 Lは、 所定の粒径にされると、 分散室 5 5に設けられた排 出口 5 5 bより配管 T 3を介して、 粉体材料の塗布装置 1 3を構成する下杵用の 粉体材料の塗布装置 4 Bの粉体材料導入口 e 1に送り込まれ、 粉体材料導入口 e 1から送り込まれた滑沢剤粉末 Lは、 その後、 貫通孔 h iを通って、 貫通孔 h i の排出口 e 2より、 下杵用の粉体材料の塗布装置 4の下方に位置している、 曰 2 2内に所定の位置まで挿入された下杵 2 4の上面 S 2 4に、 一気に、 吹き付けら れる。 When the lubricant powder L has a predetermined particle size, a powder material coating device 13 is formed from a discharge outlet 55 b provided in the dispersion chamber 55 through a pipe T 3. The lubricant powder L sent to the powder material inlet e1 of the powder material application device 4B for the lower punch and sent from the powder material inlet e1 then passes through the through hole hi. It is located below the powder material applicator 4 for the lower punch from the outlet e 2 of the through hole hi. The upper surface S 2 of the lower punch 24 inserted to a predetermined position in the lower punch 22 4, At a stretch, it is sprayed.
この時、 下杵 2 4の上面 S 2 4の中心部から、 曰 2 2の内周壁面 S 2 2方向に 広がるような気流が発生するので、 曰 2 2の内周壁面 S 2 2にも、 滑沢剤粉末 L が付着する。 At this time, from the center of the upper surface S24 of the lower punch 24, an airflow is generated that spreads in the direction of the inner peripheral wall S22 of 22. The lubricant powder L adheres.
次に、 下杵 2 4の上面 S 2 4や、 曰 2 2の内周壁面 S 2 2に、 堆積している余 分な滑沢剤粉末 Lは、 第 1の吸引手段 1 1を駆動することにより、 長溝 D 1及び 長溝 D 2と、 回転テーブル 2 1とにより形成されている空間に、 排出口 e 2から スリヅト部 3 2方向へ向かう気流に乗って、 スリット部 3 2へ供給される。 Next, the excess lubricant powder L deposited on the upper surface S 24 of the lower punch 24 and the inner peripheral wall surface S 22 of the lower punch 24 drives the first suction means 11. As a result, the space formed by the long grooves D 1 and the long grooves D 2 and the rotary table 21 is supplied to the slit section 32 by the airflow from the discharge port e 2 toward the slit section 32. .
このスリット部 3 2の上方には、 第 1の吸引手段 1 1を駆動することにより、 スリット部 3 2の領域に、 万遍なく、 スリット部 3 2から第 1の吸引手段 1 1の 吸引口 T 4 aに向かう気流が発生しているため、 スリツト部 3 2から排出された、 空気に混和した滑沢剤粉末 Lは、 この気流に乗って、 吸引口 T 4 a方向へ移動す By driving the first suction means 11 above the slit section 32, the suction port of the first suction means 11 from the slit section 32 is uniformly distributed in the area of the slit section 32. Since the airflow toward T4a is generated, the lubricant powder L mixed with the air discharged from the slit portion 32 moves on the airflow and moves in the direction of the suction port T4a.
^> o ^> o
このとき、 上杵収容溝 3 1内を通される上杵 2 3の下面 S 2 3には、 上杵 2 3 が、 スリット部 3 2の起端部 e sから終端部 e eまで移動する間に、 万遍なく、 下方より上方に向かってくる滑沢剤粉末 Lが、 下面に概ね垂直方向に衝突し続け ることになる。 At this time, on the lower surface S 23 of the upper punch 23 passed through the upper punch receiving groove 3 1, the upper punch 23 moves while moving from the starting end es of the slit portion 32 to the terminal end ee. However, the lubricant powder L coming from above to below from all over will continue to collide with the lower surface in a substantially vertical direction.
このようにして、 重力の関係で付着し難い、 上杵 2 3の下面 S 2 3へ、 滑沢剤 粉末 Lが均一に塗布されることとなる。 In this way, the lubricant powder L is uniformly applied to the lower surface S23 of the upper punch 23, which hardly adheres due to gravity.
一方、 下杵 2 4の上面 S 2 4や、 曰 2 2の内周壁面 S 2 2に、 付着したり、 堆 積したりした余分な滑沢剤粉末 Lは、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5より吸引される。 その結果、 下杵 2 4の上面 S 2 4や曰 2 2の内周壁面 S 2 2 に、 粉体材料が均一に塗布される。 〜 On the other hand, it adheres to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of The accumulated lubricant powder L is sucked from the suction port h5 of the second suction means (not shown). As a result, the powder material is uniformly applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 22. ~
その後、 成形材料充填ポイント P 2において、 フィードシユウ 2 5より成形材 料 (顆粒) Mが、 下杵 2 4が所定の位置まで挿入された曰 2 2内に充填される。 次に、 スクレ一パ 2 6により、 すり切りがされ、 臼 2 2内に充填した成形材料 (顆粒) Mの量が所定の量に調整される。 After that, at the molding material filling point P2, the molding material (granules) M is fed from the feedstock 25 into the space 22 into which the lower punch 24 has been inserted to a predetermined position. Next, the scraper 26 is used for grinding, and the amount of the molding material (granules) M filled in the mortar 22 is adjusted to a predetermined amount.
次いで、 スクレーバ 2 6により、 すり切りがされ、 所定量の成形材料 (顆粒) Mが充填された臼 2 2は、 回転テーブル 2 1の回転に伴って、 予備圧縮ポイント P 3に送られ、 ここで、 予圧ロール 2 7、 2 7により、 組となる上杵 2 3及び下 杵 2 4により予備圧縮がされた後、 本圧縮ポイント P 4に送られ、 本圧ロール 2 8、 2 8により、 組となる上杵 2 3及び下杵 2 4により、 所定の打錠圧により圧 縮成形され錠剤 tにされる。 Then, the mortar 22, which has been abraded by the scraper 26 and filled with a predetermined amount of the molding material (granules) M, is sent to the pre-compression point P 3 with the rotation of the turntable 21, where After being pre-compressed by a pair of upper punches 23 and lower punches 24 by the preload rolls 27, 27, they are sent to the final compression point P4, where they are assembled by the main pressure rolls 28, 28. The upper punch 23 and the lower punch 24 are compressed by a predetermined tableting pressure into tablets t.
本圧縮ボイント P 4において圧縮成形されることにより製造された錠剤 tは、 順次、 錠剤排出ボイント P 5に送られ、 錠剤排出ボイント P 5において、 曰 2 2 内を下杵 2 4が上方に移動することにより、 曰 2 2外へと排出され、 案内板 2 9 により所定の場所に取り出されるようになつている。 The tablets t produced by compression molding at the compression point P 4 are sequentially sent to the tablet discharge point P 5, where the lower punch 24 moves upwards in the tablet discharge point P 5. As a result, the water is discharged out of 22 and is taken out to a predetermined place by the guide plate 29.
その後、 曰 2 2、 上杵 2 3及び下杵 2 4は、 吸引手段 (図示せず。 ) 等により、 順次、 各々の表面が清浄された後、 再び、 滑沢剤噴霧ポイント P 1に送られ、 次 の打錠工程に備えるようになつている。 After that, the surface 22 of the upper punch 23, the upper punch 23 and the lower punch 24 are sequentially cleaned by suction means (not shown) or the like, and then sent to the lubricant spraying point P1 again. It is prepared for the next tableting process.
この外部滑沢式打錠機 1 Bでは、 以上のような工程を連続して行うことにより、 錠剤 Tを連続的に製造するようになっている。 In the external lubricating tableting machine 1B, the tablet T is continuously produced by continuously performing the above-described steps.
この外部割沢式打錠機 1 Bでは、 打錠機 2の複数の臼 2 2 · · 'の各々の内周 壁面 S 2 2 · · ·、 上杵 2 3 · · ·の各々の下面 S 2 3 · · ·、 及び、 下杵 2 4 • ■ 'の各々の上面 S 2 4 · · ·に、 均一に、 滑沢剤粉末 Lを塗布できるので、 錠剤 tを連続打錠する際に、 上杵 2 3 · · ·、 下杵 2 4 · · ·、 及び臼 2 2 · · 'に、 ギシヅキを生じることなく、 且つ、 打錠障害 (ラミネ一ティング、 キヤヅ ビング、 ステイツキング等) を生じることなく、 連続打錠が可能になる。 In this external split type tableting machine 1B, the inner peripheral wall surface S2 2 ··· of each of the plurality of dies 2 2 ··· ′ of the tableting machine 2 and the lower surface S of each of the upper punches 2 3 ··· 2 3 · · · and lower punch 2 4 · · · 'can evenly apply the lubricant powder L to the upper surface S 2 4 · · · The upper punch 2 3 · · · the lower punch 2 4 · · and the mortar 2 2 · · 'cause no tableting and tableting problems (laminating, caving, statusing, etc.) Without the need for continuous tableting.
これにより、 敢えて、 成形材料 M中には、 滑沢剤粉末 Lを添加しなくても、 生 産ベースで、 錠剤の製造が可能になる。 As a result, even if the lubricant powder L is not added to the molding material M, Production of tablets is possible on a production basis.
また、 粉体材料として、 滑沢剤粉末 Lの代わりに、 表面改質剤を用いた場合に は、 上杵 2 3 · · ·の各々の下面 S 2 3 · · ·、 下杵 2 4 · · ·の各々の上面 S 2 4 · · ·、 及び、 曰2 2 ' . 'の各々の内周壁面 S 2 2の各々に、 表面改質剤 を均一に塗布できる。 したがって、 この外部割沢式打錠機 1 Bを用いれば、 錠剤 tの表面に表面改質剤が均一に塗布された錠剤を製造できるようになる。 When a surface modifier is used instead of the lubricant powder L as the powder material, the lower surface S 23 of each of the upper punches 23 and the lower punches 24 The surface modifying agent can be uniformly applied to each of the inner peripheral wall surfaces S22 of each of the upper surfaces S2 4,. Therefore, by using this external splittable tableting machine 1B, it becomes possible to produce a tablet in which the surface modifier is uniformly applied to the surface of the tablet t.
更に、 上述したように、 上杵用の粉体材料の塗布装置 3 Bのスリット部 3 2の 幅 W 3 2を、 錠剤に形成する割線や刻印の領域の幅に概ね一致するようにすれば、 上杵収容溝 3 1内を移動してくる、 上杵 2 3 · · ·の各々の下面 S 2 3 · · ·の、 割線や刻印を形成する部分、 即ち、 複雑な凸部が形成されている部分を中心にし て、 上杵 2 3 · · ·の各々の下面 S 2 3 · · ■に、 十分に且つ均一に、 粉体材料 が塗布できる。 Further, as described above, if the width W32 of the slit portion 32 of the powder material application device 3B for the upper punch is made to substantially match the width of the area of the score line or the mark formed on the tablet, The upper punches 23, which move in the upper punch receiving groove 31, form a part forming a score line or an engraving of the lower surface S23 of each of the upper punches 23, that is, a complex convex portion is formed. The powder material can be sufficiently and uniformly applied to the lower surface S2 3... Of each of the upper punches 2 3.
これにより、 粉体材料として、 滑沢剤粉末 Lを用いた場合には、 錠剤の、 割線 や刻印を設けた部分、 即ち、 複雑な凹凸が形成されている部分で、 ラミネーティ ング、 キヤヅビング、 ステイツキングを生じること無く、 錠剤を製造することが できる。 As a result, when the lubricant powder L is used as the powder material, laminating, caving, and states of the tablet are provided at the parts where the score lines and markings are provided, that is, at the parts where complex irregularities are formed. Tablets can be manufactured without kinging.
したがって、 この外部滑沢式打錠機 1 Bを用いれば、 従来は、 生産ベースで製 造することが難しかった、 割線や刻印を設けた外部滑沢錠剤を、 生産ベースで製 造することができるようになる。 また、 粉体材料として、 表面改質剤粉末を用い た場合には、 従来、 製造するのが困難であった、 割線や刻印が設けられた部分に も、 均一に、 表面改質剤が塗布されだ錠剤を製造することができるようになる。 また、 この外部滑沢式打錠機 1 Bでは、 下杵用の粉体材料の塗布装置 4に、 第 2の吸引手段 (図示せず。 ) を設け、 錠剤 tを製造する間、 第 2の吸引手段 (図 示せず。 ) を駆動させて、 スリヅト部 h 5により、 下杵 2 4 · · ·の各々の下面 S 2 4 · · ·、 及び、 臼 2 2 · · ·の各々の内周壁面 S 2 2 · · ·に、 余分に付 着している粉体材料、 及び/又は、 回転テーブル 2 1上の余分な粉体材料を除去 するようにしている。 Therefore, if this external lubricating tableting machine 1B is used, it is conventionally difficult to produce on an industrial basis, but it is possible to produce an external lubricating tablet with a score line or engraving on a production basis. become able to. In addition, when the surface modifier powder is used as the powder material, the surface modifier is uniformly applied to the part where the score line or the marking is provided, which has been difficult to manufacture conventionally. Tablets can be manufactured. Further, in this external lubricating tableting machine 1B, a second suction means (not shown) is provided in the powder material applying device 4 for the lower punch, and the second pressing means is used during the production of the tablet t. The suction means (not shown in the figure) is driven, and the lower surface S 24 of each of the lower punches 24 and the mortar 22 are driven by the slit portion h5. Excessive powder material adhering to the peripheral wall surface S22 and / or excess powder material on the turntable 21 are removed.
したがって、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5より下流位置にある、 成形材料充填ボイント P 2の位置で、 下杵 2 4及び臼 2 2により形成される空間 内に、 順次、 成形材料 Mを充填する工程において、 下杵 2 4及び曰 2 2に余分に 付着している粉体材料、 及び/又は、 回転テーブル 2 1上の余分な粉体材料が、 成形材料中に、 混入することを防ぐことができる。 、'- これにより、 内部に、 滑沢剤粉末 Lや表面改質剤を含むことの無い、 外部滑沢 錠剤を、 効率よく製造することもできる。 Therefore, the space formed by the lower punch 24 and the die 22 at the position of the molding material filling point P 2 located downstream of the suction port h 5 of the second suction means (not shown). In the step of successively filling the molding material M, the powder material extraly attached to the lower punch 24 and said 22 and / or the excess powder material on the turntable 21 are Mixing into the molding material can be prevented. This makes it possible to efficiently manufacture an external lubricating tablet that does not contain the lubricant powder L or a surface modifier therein.
更に、 この外部滑沢式打錠機 1 Bでは、 長溝 D 1及び長溝 D 2を介して、 排出 口 e 2から、 臼 2 2 ■ · ·、 及び、 曰 2 2 · · 'の各々内に所定の位置まで挿入 された下杵 2 4 · · ·の各々の上面 S 2 4 · · 'に吹き付けられた滑沢剤粉末 L を、 更に、 スリット部 3 2から排出できるようにしているので、 図 1と図 1 7と の対比より明らかなように、 粉体材料の吐出装置 (定量フィーダ) 5と、 粉#¾" 料の塗布装置 3との間の配管 T 3は、 図 1に示す外部滑沢式打錠機 1のように、 2本の配管 T 3 a、 T 3 bにする必要がなくなるので、 装置構成を簡単化できる という効果もある。 Furthermore, in this external lubricating tableting machine 1B, through the long groove D1 and the long groove D2, from the discharge port e2, each of the mortar 2 2 Since the lubricant powder L sprayed on the upper surface S2 4 of each of the lower punches 24 inserted into a predetermined position can be further discharged from the slit portion 32, As is clear from the comparison between FIG. 1 and FIG. 17, the pipe T 3 between the powder material discharge device (quantitative feeder) 5 and the powder # ¾ ”material application device 3 is shown in FIG. Unlike the external lubricating tablet press 1, there is no need to use two pipes T3a and T3b, so that there is also an effect that the device configuration can be simplified.
更にまた、 この粉体材料の塗布装置 1 3では、 下杵用の粉体材料の塗布装置 4 に、 回転テーブル 2 1の回転方向とは逆方向 (上流側) の位置に、 上杵用の粉体 材料の塗布装置 3を接続し、 空気に混和した滑沢剤粉末 Lを、 排出口 e 2、 長溝 D l、 長溝 D 2及びスリット部 3 2と、 回転テーブル 2 1の回転方向とは逆方向 に流すようにしているので、 上杵収容溝 3 1内を移動する上杵 2 3の移動方向と は、 逆方向に、 滑沢剤粉末 Lが混和された空気の気流が流れることになるので、 上杵 2 3の下面 S 2 3に、 効率良く、 滑沢剤粉末 Lを塗布できる。 Further, in the powder material coating device 13, the lower punch material coating device 4 is placed in a position opposite to the rotation direction of the rotary table 21 (upstream side). The powder material coating device 3 is connected, and the lubricant powder L mixed with the air is discharged into the outlet e2, the long groove Dl, the long groove D2, the slit 32, and the rotation direction of the rotary table 21. Since the air flows in the opposite direction, the moving direction of the upper punch 23 moving in the upper punch receiving groove 31 is opposite to that of the airflow containing the lubricant powder L. Therefore, the lubricant powder L can be efficiently applied to the lower surface S 23 of the upper punch 23.
尚、 この下杵用の粉体材料の塗布装置 4 Bでも、 図 2 0及び図 2 1に示すよう に、 排出口 e 2と、 吸引口 h 5との間の距離 L ( e 2 - h 5 ) を、 少なくとも、 曰 2 2の直径 D 2 2に比べ、 長くなるようにしている。 In addition, in the powder material applicator 4 B for the lower punch, as shown in FIGS. 20 and 21, the distance L (e 2 −h) between the discharge port e 2 and the suction port h 5. 5) is made longer than at least the diameter D22 of 22.
即ち、 この下杵用の粉体材料の塗布装置 4 Bでも、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5を、 少なくとも、 排出口 e 2が設けられている位置から、 回転テ一 プル 2 1に設けられる、 複数の曰 2 2 · · ·の各々の直径 D 2 2より、 離れた位 置に設けている (L ( e 2 - h 5 ) > D 2 2 )。 That is, in the powder material application device 4B for the lower punch, the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. It is provided at a position distant from the diameter D22 of each of a plurality of statements 22 provided on the tape 21 (L (e2-h5)> D22).
従って、 この下杵用の粉体材料の塗布装置 4 Bでは、 下杵 2 4の上面 S 2 4及 び臼 2 2の内周壁面 S 2 2に塗布された粉体材料 (この例では、 滑沢剤粉末 L) の中、 下杵 2 4の上面 S 2 4及び臼 2 2の内周壁面 S 2 2にとつて余分な粉体材 料 (この例では、 滑沢剤粉末 L ) を、.臼 2 2内に所定の位置まで挿入された下杵 2 4の上面 S 2 4に、 空気脈動波の気流に分散した粉体材料 、を-直接吹き付ける場 所 (即ち、 排出口 e 2 ) とは、 臼 2 2を介して、 導通しない場所で、 吸引除去す るようにしているので、 曰 2 2内に所定の位置まで挿入された下杵 2 4の上面 S 2 4に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける条件に影響を与 えることなく、 下杵 2 4の上面 S 2 4及び曰 2 2の内周壁面 S 2 2に塗布された 粉体材料 (この例では、 滑沢剤粉末 L ) の中、 下杵 2 4の上面 S 2 4及び曰 2 2 の内周壁面 S 2 2にとつて余分な粉体材料 (この例では、 滑沢剤粉末 L ) を、 吸 引除去することができる。 Accordingly, in the powder material applying device 4B for the lower punch, the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the die 22 (in this example, Lubricant powder L) The extra powder material (in this example, lubricant powder L) is added to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the mortar 22 in the mortar 22. Where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted into a predetermined position into the lower punch 24 (that is, the discharge port e 2) Since the suction is removed at a place where it does not conduct through 2, the air flow of the air pulsating wave is dispersed on the upper surface S 24 of the lower punch 24 inserted to a predetermined position in 2 The powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 24 without affecting the conditions under which the powder material is directly sprayed (in this example, The excess powder material (in this example, lubricant powder L) is sucked into the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 in the powder L). Can be removed.
図 2 3は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す平面図 Cある。 FIG. 23 is a plan view C schematically showing another example of the powder material coating apparatus according to the present invention.
この粉体材料の塗布装置 1 3 Aは、 スリット部 3 2の形状が、 ジグザグ形状に されている以外は、 図 2 0に示す粉体材料の塗布装置 1 3と同様であるので、 相 当する部材装置には、 相当する参照符号を付して、 その説明を省略する。 The powder material coating device 13A is the same as the powder material coating device 13 shown in FIG. 20 except that the shape of the slit portion 32 is zigzag. The corresponding members are denoted by the corresponding reference numerals, and description thereof will be omitted.
この粉^ #料の塗布装置 1 3 Aでは、 スリット部 3 2の形状を、 ジグザグ开 にしているので、 上杵収容溝 3 1内を移動してくる、 上杵 2 3は、 スリヅト部 3 2の形状を、 複数の上杵 2 3 · · 'の回転軌道 O rに沿って、 ただ単に、 湾曲さ せている、 粉体材料の塗布装置 1 3に比べて、 上杵収容溝 3 1内を移動する際に、 より長いスリット部 3 1を通過したことになるので、 尚、 一層、 上杵 2 3 · · · の各々の下面 S 2 3 · ' ·に、 十分且つ均一に、 粉体材料を塗布することができ る。 In the powder coating device 13 A, since the slit portion 32 has a zigzag shape, the slit portion 32 moves in the upper punch receiving groove 31. The shape of 2 is simply curved along the rotation trajectory Or of multiple upper punches 2 3 When moving through the inside, since it has passed through the longer slit portion 31, the lower surface S 2 3 ′ of each of the upper punches 2 3. Body material can be applied.
これにより、 粉体材料として、 滑沢剤粉末 Lを用いた場合には、 たとえ、 上杵 2 3 · · ·の下面 S 2 3 · · ·に、 錠剤 tの各々に、 割線や刻印を形成するため の凹凸を設けた場合にも、 製造される錠剤 tに、 ラミネ一ティングや、 キヤヅビ ングや、 ステイツキング等の打錠障害を生じることなく、 錠剤 tを製造すること ができる。 As a result, when the lubricant powder L is used as the powder material, a score line or a mark is formed on each of the tablets t, for example, on the lower surface S 23 of the upper punch 23. Even when the unevenness is provided, the tablet t can be manufactured without causing tableting troubles such as laminating, cabling, and stateing on the manufactured tablet t.
尚、 この下杵用の粉体材料の塗布装置 4 Bでも、 図 2 3に示すように、 排出口 e 2と、 吸引口 h 5との間の距離 L ( e 2 - h 5 ) を、 少なくとも、 曰 2 2の直 径 D 2 2に比べ、 長くなるようにしている。 In addition, in the powder material application device 4 B for the lower punch, as shown in FIG. 23, the distance L (e 2 -h 5) between the discharge port e 2 and the suction port h 5 is defined as At least It is made longer than the diameter D22.
即ち、 この下杵用の粉体材料の塗布装置 4 Bでも、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5を、 少なくとも、 排出口 e 2が設けられている位置から、 回転テー ブル 2 1に設けられる、 複数の曰 2 2 · · 'の各々の直径 D 2 2より、 離れた位 置に設けている (L ( e 2— h 5 ) > D 2 2 ) 。 That is, in the powder material application device 4B for the lower punch, the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. It is provided at a position further away from the diameter D 22 of each of a plurality of statements 22... Provided on the table 21 (L (e 2 — h 5)> D 22).
従って、 この下杵用の粉体材料の塗布装置 4 Bでも、 下杵 2 4の上面 S 2 4及 び曰 2 2の内周壁面 S 2 2に塗布された粉体材料 (この例では、 滑沢剤粉末 L ) の中、 下杵 2 4の上面 S 2 4及び曰 2 2の内周壁面 S 2 2にとつて余分な粉体材 料 (この例では、 滑沢剤粉末 L ) を、 曰 2 2内に所定の位置まで挿入された下杵 2 4の上面 S 2 4に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける場 所 (即ち、 排出口 e 2 ) とは、 曰 2 2を介して、 導通しない場所で、 吸引除去す るようにしているので、 曰 2 2内に所定の位置まで挿入された下杵 2 4の上面 S 2 4に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける条件に影響を与 えることなく、 下杵 2 4の上面 S 2 4及び曰 2 2の内周壁面 S 2 2に塗布された 粉体材料 (この例では、 滑沢剤粉末 L ) の中、 下杵 2 4の上面 S 2 4及び曰 2 2 の内周壁面 S 2 2にとつて余分な粉体材料 (この例では、 滑沢剤粉末 L ) を、 吸 引除去することができる。 Therefore, the powder material coating device 4 B for the lower punch also uses the powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 22 (in this example, In the lubricant powder L), extra powder material (in this example, lubricant powder L) is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 22. The place where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted to a predetermined position in 22 (that is, the discharge port e 2) , Says that the air is removed by suction at a place where it does not conduct through 22, and the upper surface S 24 of the lower punch 24 inserted to a predetermined position in the The powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 24 without affecting the conditions for directly blowing the powder material dispersed in the airflow (in this example, The lubricant powder L) (In this example, wax powder L) upper surface S 2 4 and 曰 2 2 of the inner circumferential wall surface S 2 extra powder material Te convex to second lower punch 2 4 can be Aspirate removed.
図 2 4は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す平面図 である。 FIG. 24 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
この粉体材料の塗布装置 1 3 Bは、 スリット部 3 2の上方に、 更に 所定の孔 径を有するメッシュ手段 1 4を設けている以外は、 図 2 0に示す粉体材料の塗布 装置 1 3と同様であるので、 相当する部材装置には、 相当する参照符号を付して、 その説明を省略する。 The powder material coating apparatus 13 B shown in FIG. 20 is different from the powder material coating apparatus 1 shown in FIG. 20 except that a mesh means 14 having a predetermined hole diameter is further provided above the slit portion 32. Since this is the same as 3, the corresponding member devices are denoted by the corresponding reference numerals, and description thereof will be omitted.
この粉体材料の塗布装置 1 3 Bでは、 スリヅト部 3 2の上方に、 更に、 所定の 孔径を有するメッシュ手段 1 4を設けているので、 スリッ卜部 3 2から排出され る粉体材料の中、 メッシュ手段 1 4の孔径より大きな粒子は、 メッシュ手段 1 4 により補集 (キャッチ) されることになる。 この結果、 上杵 2 3 · · 'の各々の 下面 S 2 3 · · ·には、 所定の粒径より大粒の粉体材料が付着するのを防止でき る。 これにより、 上杵 2 3 · · 'の各々の下面 S 2 3 · · ·に、 粒径の揃った粉 ^料を、 均一に塗布できる。 In the powder material application device 13B, since the mesh means 14 having a predetermined hole diameter is further provided above the slit portion 32, the powder material discharged from the slit portion 32 may be used. However, particles larger than the pore size of the mesh means 14 are collected by the mesh means 14. As a result, it is possible to prevent the powder material larger than the predetermined particle diameter from adhering to the lower surface S 23 ··· of each of the upper punches 23 ··· '. As a result, the lower surface S 2 3 · · · of each of the upper punches 2 3 The material can be applied evenly.
また、 メッシュ手段 1 4により、 第 1の吸引手段 1 1を駆動することにより発 生させて、 スリット部 3 2から上方に移動する気流が整流さ 、れ'-る。 このメッシュ 手段 1 4の整流作用によっても、 上杵 2 3 · · ·の各々の下面 S 2 3 · · ·に、 粉体材料を、 均一に塗布される。 In addition, the mesh means 14 is generated by driving the first suction means 11, so that the airflow moving upward from the slit part 32 is straightened. The powder material is uniformly applied to the lower surface S 23 of each of the upper punches 23 also by the rectifying action of the mesh means 14.
従って、 粉体材料として、 滑沢剤粉末 Lを用いた場合には、 たとえ、 上杵 2 3 • - ·の下面 S 2 3 · · ·に、 錠剤 tの各々に、 割線や刻印を形成するための凹 凸を設けた場合にも、 製造される錠剤 tに、 ラミネ一ティングや、 キヤッビング や、 ステイツキング等の打錠障害を生じることなく、 錠剤 tを製造することがで ぎる。 Therefore, when the lubricant powder L is used as the powder material, a score line or a mark is formed on each of the tablets t on the lower surface S 23 of the upper punch 2 3. Even when the convex and concave portions are provided, the tablet t can be manufactured without causing tableting obstacles such as laminating, cabbing, and stateing on the manufactured tablet t.
尚、 この下杵用の粉体材料の塗布装置 4 Bでも、 図 2 4に示すように、 排出口 e 2と、 吸引口 h 5との間の距離 L ( e 2 - h 5 ) を、 少なくとも、 曰 2 2の直 径 D 2 2に比べ、 長くなるようにしている。 In addition, in the powder material application device 4B for the lower punch, as shown in FIG. 24, the distance L (e2−h5) between the discharge port e2 and the suction port h5 is determined as follows. At least, it is designed to be longer than the 22 diameter D22.
即ち、 この下杵用の粉体材料の塗布装置 4 Bでも、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5を、 少なくとも、 排出口 e 2が設けられている位置から、 回転テー ブリレ 2 1に設けられる、 複数の曰 2 2 · · ·の各々の直径 D 2 2より、 離れた位 置に設けている (L ( e 2 - h 5 ) > D 2 2 )。 That is, in the powder material application device 4B for the lower punch, the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. It is provided at a distance from the diameter D22 of each of a plurality of statements 22 provided on the table 21 (L (e2-h5)> D22).
従って、 この下杵用の粉体材料の塗布装置 4 Bでも、 下杵 2 4の上面 S 2 4及 び曰 2 2の内周壁面 S 2 2に塗布された粉体材料 (この例では、 滑沢剤粉末 L ) の中、 下杵 2 4の上面 S 2 4及び曰 2 2の内周壁面 S 2 2にとつて余分な粉体材 料 (この例では、 滑沢剤粉末 L ) を、 臼 2 2内に所定の位置まで挿入された下杵 2 4の上面 S 2 4に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける場 所 (即ち、 排出口 e 2 ) とは、 臼 2 2を介して、 導通しない場所で、 吸引除去す るようにしているので、 臼 2 2内に所定の位置まで挿入された下杵 2 4の上面 S 2 4に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける条件に影響を与 えることなく、 下杵 2 4の上面 S 2 4及び臼 2 2の内周壁面 S 2 2に塗布された 粉体材料 (この例では、 滑沢剤粉末 L ) の中、 下杵 2 4の上面 S 2 4及び臼 2 2 の内周壁面 S 2 2にとつて余分な粉体材料 (この例では、 滑沢剤粉末 L ) を、 吸 引除去することができる。 図 25は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す平面図 であり、 又、 図 26は、 図 25中、 XXVI— XXVI線に従う概略的な断面図 である。 Therefore, the powder material coating device 4 B for the lower punch also uses the powder material applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 22 (in this example, In the lubricant powder L), extra powder material (in this example, lubricant powder L) is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 22. The place where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted into the mortar 22 to a predetermined position (that is, the discharge port e 2) Since the air is removed through the mortar 22 in a place where it does not conduct, the air pulsation wave is applied to the upper surface S 24 of the lower punch 24 inserted into the mortar 22 to a predetermined position. The powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the mill 22 without affecting the conditions for directly blowing the powder material dispersed in the airflow (in this example, The lubricant powder L) (In this example, wax powder L) upper surface S 2 4 and excess powder material Te convex on the inner peripheral wall surface S 2 2 of the die 2 2 lower punch 2 4 can be Aspirate removed. FIG. 25 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention, and FIG. 26 is a schematic sectional view taken along line XXVI-XXVI in FIG. .
尚、 図 26では、 図面の理解を容易とするために、 図 26中に表されている、 2本の上杵 23、 23の中、 一方の上杵 23を想像線で示している。 In FIG. 26, one of the two upper punches 23, 23 shown in FIG. 26 is shown by an imaginary line to facilitate understanding of the drawing.
この粉体材料の塗布装置 13Cは、 下杵用の粉体材料の塗布装置 4 Bの代わり に、 回転テーブル 21に対向する表面 S 4 aの、 排出口 e2の前段部に、 スリツ ト状の成形材料吸引口 h 6 aを有する第 3の吸弓 I手段 (図示せず。 ) を、 更に備 える、 下杵用の粉体材料の塗布装置 4 Cを用いている。 Instead of the powder material coating device 4B for the lower punch, the powder material coating device 13C is provided with a slit-like shape at the front stage of the discharge port e2 on the surface S4a facing the rotary table 21. A powder material applicator 4C for lower punch is further provided with a third sucking I means (not shown) having a molding material suction port h6a.
尚、 図 26中、 h 7で示す部分は、 排出口 e 2から、 正圧の空気脈動波ととも に噴霧された粉体材料 (この例では、 滑沢剤粉末) を、 上杵用の粉体材料の塗布 装置 3Bへ誘導する導管を示しており、 h7aは、 導管 h7の開口部を示してい る。 In FIG. 26, the portion indicated by h7 is a powder material (in this example, a lubricant powder) sprayed from the outlet e2 together with the positive pressure air pulsation wave for the upper punch. A conduit leading to the powder material application device 3B is shown, and h7a is an opening of the conduit h7.
この第 3の吸引手段 (図示せず。 ) の成形材料吸引口 h6 aは、 複数の下杵 2 3. · ■の上面 S 23 · · ·、 複数の臼 22 · . ·の各々の内周壁面 S 22 · · •及び複数の曰 22■ · 'の周辺に付着している成形材料 Mを、 順次、 除去する ために設けられているものであり、 複数の曰 22 · ■ ·の回転軌道 Orに概ね直 交するように、 且つ、 複数の臼 22 · · ·の各々の直径と概ね一致する幅か、 そ れよりやや大きい幅を有している。 The molding material suction port h6a of the third suction means (not shown) is provided on the inner periphery of each of the upper surfaces S23,. It is provided to sequentially remove the molding material M adhering around the wall S 22 ··· and a plurality of said 22 ■ · '. It has a width that is approximately perpendicular to Or and that is approximately the same as or slightly larger than the diameter of each of the plurality of dies 22.
そして、 下杵用の粉体材料の塗布装置 4 Cの排出口 e 2より排出された、 空気 に混和された粉体材料を、 上杵用の粉体材料の塗布装置 3 Bのスリット部 32へ 供給する際に、 第 3の吸引手段 (図示せず。 ) を吸引した際に、 成形材料吸引口 h 6 aから吸引されるのを防ぐために、 長溝 D1ではなく、 下杵用の粉#¾料の 塗布装置 4 C内を、 成形材料吸引口 h6 aとは導通しないように設けた、 貫通孔 h7により、 排出口 e 2とスリット部 32とを接続するようにしている。 Then, the powder material mixed with air discharged from the outlet e2 of the powder material applying device 4C for the lower punch and the powder material applying device 3B for the upper punch 3 In order to prevent the suction from the molding material suction port h6a when sucking the third suction means (not shown) when feeding the powder to the lower punch, the powder for the lower punch is used instead of the long groove D1. The discharge port e2 and the slit section 32 are connected to each other by a through hole h7 provided in the material coating apparatus 4C so as not to conduct with the molding material suction port h6a.
この粉体材料の塗布装置 13 Cでは、 滑沢剤粉末 Lを排出する排出口 e 2の前 段部に、 成形材料吸引口 h 6 aを有する第 3の吸引手段 (図示せず。 ) を設け、 滑沢剤粉末 Lを、 臼 22 · · 'の各々噴霧する前に、 臼 22 · · 'の各々の内周 壁面 S 22 · · ·及び下杵 24 · · ·の各々の上面 S 24 · · ·を清浄している ので、 前工程で使用した成形材料 Mや滑沢剤粉末 Lが、 次工程で製造される錠剤 t · · ·中に混入することがないので、 錠剤 t · · ·を連続的に製造しても、 錠 剤 t · · ·間で、 滑沢剤粉末 Lの使用量等に不均一を生じない。 これにより、 同 じ規格の錠剤 t · · ·を連続的に製造できる。 In the powder material application device 13C, a third suction means (not shown) having a molding material suction port h6a is provided at a stage preceding the discharge port e2 for discharging the lubricant powder L. Before spraying the lubricant powder L onto each of the dies 22 ··· ', the inner peripheral wall S 22 ··· of each of the dies 22 ··· and the upper surface S 24 of the lower punch 24 ··· · · · Clean Since the molding material M and lubricant powder L used in the previous process do not mix into the tablets t produced in the next process, tablets t Also, there is no non-uniformity in the amount of the lubricant powder L used between the tablets. This enables continuous production of tablets t · · · of the same standard.
尚、 この下杵用の粉体材料の塗布装置 4 Cでも、 図 26に示すように、 排出口 e 2と、 吸引口 h5との間の距離 L (e 2-h5) を、 少なくとも、 臼 22の直 径 D 22に比べ、 長くなるようにしている。 As shown in Fig. 26, the powder material application device 4C for the lower punch also requires the distance L (e2-h5) between the discharge port e2 and the suction port h5 to be at least 22 is made longer than the diameter D22.
即ち、 この下杵用の粉体材料の塗布装置 4 Cでは、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5を、 少なくとも、 排出口 e 2が設けられている位置から、 回転テー ブル 21に設けられる、 複数の曰 22 · · ·の各々の直径 D 22より、 離れた位 置に設けている (L (e 2-h5) >D 22) 。 That is, in the powder material applying device 4C for the lower punch, the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. It is provided at a position further away from the diameter D22 of each of a plurality of statements 22 provided on the table 21 (L (e2-h5)> D22).
従って、 この下杵用の粉体材料の塗布装置 4 Cでは、 下杵 24の上面 S 24及 び曰 22の内周壁面 S 22に塗布された粉体材料 (この例では、 滑沢剤粉末 L) の中、 下杵 24の上面 S 24及び曰 22の内周壁面 S 22にとつて余分な粉体材 料 (この例では、 滑沢剤粉末 L) を、 曰 22内に所定の位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける場 所 (即ち、 排出口 e 2) とは、 曰 22を介して、 導通しない場所で、 吸引除去す るようにしているので、 臼 22内に所定の位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける条件に影響を与 えることなく、 下杵 24の上面 S 24及び臼 22の内周壁面 S 22に塗布された 粉体材料 (この例では、 滑沢剤粉末 L) の中、 下杵 24の上面 S 24及び臼 22 の内周壁面 S 22にとつて余分な粉体材料 (この例では、 滑沢剤粉末 L) を、 吸 引除去することができる。 Therefore, in the powder material applying apparatus 4C for the lower punch, the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 (in this example, the lubricant powder In L), extra powder material (in this example, lubricant powder L) is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 at a predetermined position in the lower 22. A place where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted up to (i.e., the discharge port e 2) However, since suction removal is performed, the condition that the powder material dispersed in the air current of the air pulsating wave is directly blown on the upper surface S 24 of the lower punch 24 inserted to the predetermined position in the die 22 is affected. The powder material (in this example, lubricant powder L) applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the die 22 without being removed, the upper surface of the lower punch 24 Excess powder material (in this example, lubricant powder L) can be sucked and removed from the inner peripheral wall S22 of S24 and the mortar 22.
更に、 この下杵用の粉体材料の塗布装置 4 Cでは、 図 26に示すように、 排出 口 e 2と、 吸引口 h6 aとの間の距離 L (e 2-h6 a) を、 少なくとも、 曰 2 2の直径 D 22に比べ、 長くなるようにしている。 Further, in the powder material application device 4C for the lower punch, as shown in FIG. 26, the distance L (e2-h6a) between the discharge port e2 and the suction port h6a is set to at least , Says that it is longer than 22 diameter D22.
即ち、 この下杵用の粉体材料の塗布装置 4 Cでは、 第 3の吸引手段 (図示せず。 ) の吸引口 h 6 aを、 少なくとも、 排出口 e 2が設けられている位置から、 回転テ —ブル 21に設けられる、 複数の臼 22 · · 'の各々の直径 D 22より、 離れた 位置に設けている (L (e 2— h6) >D 22) 。 That is, in the powder material application device 4C for the lower punch, the suction port h6a of the third suction means (not shown) is moved at least from the position where the discharge port e2 is provided. The rotating table 21 is provided with a plurality of dies 22. (L (e 2—h6)> D 22).
従って、 この下杵用の粉体材料の塗布装置 4 Cでは、 下杵 24の上面 S 24及 び曰 22の内周壁面 S 22に粉体材料 (この例では、 滑沢剤粉末 L).を塗布する Therefore, in the powder material application device 4C for the lower punch, the powder material (in this example, lubricant powder L) is formed on the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 22. Apply
ヽ- 前に、 たとえ、 下杵 24の上面 S 24及び臼 22の内周壁面 S 22に付着してい たとしても、 不要な成形材料や粉体材料 (この例では、 滑沢剤粉末 L) を、 曰 2 2内に所定の位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に 分散した粉# ^料を直接吹き付ける場所 (即ち、 排出口 e 2) とは、 曰 22を介 して、 導通しない場所で、 吸引除去するようにしているので、 曰 22内に所定の 位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に分散した粉体 材料を直接吹き付ける条件に影響を与えることなく、 回転テーブル 21の表面、 下杵 24の上面 S 24及び臼 22の内周壁面 S 22に付着している、 不要な成形 材料や粉体材料 (この例では、 滑沢剤粉末 L) を、 吸引除去することができる。 更に、 この下杵用の粉体材料の塗布装置 4 Cでは、 排出口 e 2と、 導管 h7の 開口部 h7 aとの間の距離 L (e 2-h7a) を、 臼 22の直径 D 22に比べ、 短かくし (L (e 2-h7 a) <D22) 、 排出口 e 2と開口部 h 7 aとの間が、 曰 22を介して、 導通するようにし、 排出口 e 2から、 正圧の空気脈動波ととも に、 噴霧された粉体材料中、 曰 22の内周壁面 S 22や、 下杵 24の上面 S 24 にとつて、 余分な粉体材料 (この例では、 滑沢剤粉末 L) が、 導管 h 7を通って、 長溝 D 2へ誘導されるようにしている。 ヽ-Even before, even if it adheres to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the die 22, unnecessary molding materials and powder materials (in this example, lubricant powder L) The place where the powder dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted to a predetermined position in 22 (that is, the discharge port e 2) Since the suction is removed at a place where it does not conduct through 22, the powder dispersed in the air current of the air pulsation wave is placed on the upper surface S 24 of the lower punch 24 inserted to a predetermined position in the 22. Unnecessary molding or powder materials adhered to the surface of the rotary table 21, the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the die 22, without affecting the conditions for directly spraying the body material. In this example, the lubricant powder L) can be removed by suction. Further, in the powder material application device 4C for the lower punch, the distance L (e2-h7a) between the outlet e2 and the opening h7a of the conduit h7 is determined by the diameter D22 of the die 22. In comparison with the above, L (e 2−h7 a) <D22), the connection between the outlet e 2 and the opening h 7 a is made to be conductive via the line 22, and from the outlet e 2, Along with the positive pressure air pulsation wave, extra powder material (in this example, smooth) is sprayed on the inner peripheral wall S22 of 22 and the upper surface S24 of the lower punch 24 in the sprayed powder material. The powder powder L) is guided through the conduit h7 into the slot D2.
また、 排出口 e 2から正圧の空気脈動波とともに噴霧された粉 ^料が、 開口 部 h 7 aから、 導管 h 7内へ誘導され易いように、 開口部 h 7 aと吸引口 h 5と の間の距離 L (h7 a-h5) を、 少なくとも、 曰 22の直径 D 22に比べ、 長 くして、 開口部 h7 aと吸引口] 15とが、 曰 22を介して、 導通することがない ようにしている (L (h7 a-h5) >D 22) 。 The opening h7a and the suction port h5 are also provided so that the powder sprayed with the positive pressure air pulsation wave from the outlet e2 is easily guided into the conduit h7 from the opening h7a. The distance L (h7 a-h5) between and is longer than at least the diameter D22 of 22 so that the opening h7a and the suction port] 15 conduct through the 22 (L (h7 a-h5)> D 22).
図 27は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す平面図 であり、 又、 図 28は、 図 27中、 XXVI I I一 XXVI I I線に従う概略的 な断面図である。 FIG. 27 is a plan view schematically showing another example of the powder material applying apparatus according to the present invention, and FIG. 28 is a schematic sectional view taken along line XXVIII-XXVIII in FIG. It is.
尚、 図 28では、 図面の理解を容易とするために、 図 28中に表されている、 2本の上杵 23、 23の中、 一方の上杵 23を想像線で示している。 この粉体材料の塗布装置 1 3 Dは、 粉体材料の塗布装置 1 3と以下の点を除け ば同様であるので、'相当する部材装置には、 相当する参照符号を付して、 その説 明を省略する。 In FIG. 28, one of the two upper punches 23, 23 shown in FIG. 28 is indicated by an imaginary line to facilitate understanding of the drawing. The powder material coating device 13D is the same as the powder material coating device 13 except for the following points. Description is omitted.
この粉体材料の塗布装置 1 3 Dは、 下杵用の粉体材料の塗布装置 4 Dに、 回転 テーブル 2 1の回転方向に順方向の位置に、 上杵用の粉体材料の塗布装置 4 Dが 接続された構造になっている。 The powder material coating device 13 D is applied to the powder material coating device 4 D for the lower punch, and the powder material coating device for the upper punch is positioned at a position in the direction of rotation of the rotary table 21. 4D has a connected structure.
尚、 この粉体材料の塗布装置 1 3 Dでは、 接続口 e 9が、 吸引口 T 4 aに接続 されており、 接続口 e 1 0が、 粉体材料の塗布装置 1 3 Dの下杵用の粉体材料の 塗布装置 4 Dの裏面 (回転テーブル 2 1に対向する側の表面) に設けられた凹所 3 cに接続されている。 接続口 e 9には、 第 1の吸引手段 1 1を接続するように してあり、 第 1の吸引手段 1 1を駆動すると、 吸引口 T 4 aに、 吸引口 T 4 a内 に向かう、 吸引雰囲気の気流が発生するようにしている。 In the powder material coating device 13D, the connection port e9 is connected to the suction port T4a, and the connection port e10 is connected to the powder material coating device 13D lower punch. It is connected to a recess 3c provided on the back surface (the surface on the side facing the rotary table 21) of the powder material application device 4D for use. The first suction means 11 is connected to the connection port e9, and when the first suction means 11 is driven, the first suction means 11 moves to the suction port T4a and goes into the suction port T4a. An airflow of a suction atmosphere is generated.
また、 接続口 e 1 0に、 吸引手段 (図示せず。 ) を接続し、 吸引手段 (図示せ ず。 ) を駆動すると、 凹所 3 cに、 凹所 3 c内に向かう、 吸引雰囲気の気流が発 生し、 回転テーブル 2 1に付着している、 成形材料や粉体材料 (この例では、 滑 沢剤粉末 L ) を除去できるようにしている。 When a suction means (not shown) is connected to the connection port e10 and the suction means (not shown) is driven, the suction atmosphere (not shown) is drawn into the recess 3c and into the recess 3c. The airflow is generated, and the molding material and the powder material (the lubricant powder L in this example) adhering to the turntable 21 can be removed.
尚、 図 2 8中、 h 8で示す部分は、 排出口 e 2から、 正圧の空気脈動波ととも に噴霧された粉体材料 (この例では、 滑沢剤粉末) を、 上杵用の粉体材料の塗布 装置 3 Dへ誘導する導管を示しており、 h 8 aは、 導管 h 8の開口部を示してい る。 In Fig. 28, the portion indicated by h8 is a powder material (in this example, a lubricant powder) sprayed from the outlet e2 together with the positive pressure air pulsation wave for the upper punch. A conduit leading to the powder material application device 3D is shown, and h8a represents an opening of the conduit h8.
下杵用の粉体材料の塗布装置 4 Dの回転テーブル 2 1に対向する側の表面 S 4 aには、 回転テーブル 2 1の回転方向に順方向 (上流側から下流方向) に、 排出 口 e 2、 吸引口 h 8 a、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5が設けられ ている。 The powder material application device for the lower punch 4 D has a surface S 4 a on the side facing the rotary table 21, which has a discharge port in the forward direction (from the upstream side to the downstream side) in the rotation direction of the rotary table 21. e2, a suction port h8a, and a suction port h5 of a second suction means (not shown) are provided.
吸引口 h 8 aは、 排出口 e 2より排出された、 空気に混和された粉体材料を、 上杵用の粉体材料の塗布装置 3 Dのスリット部 3 2へ供給する際に、 第 2の吸引 手段 (図示せず。 :) を吸引した際に、 排出口 e 2より排出された、 空気に混和さ れた粉体材料が、 弓 I口 h 5から吸引されないように、 下杵用の粉体材料の塗布装 置 4 D内を、 吸引口 h 5は導通しないように設けた、 貫通孔 h 8により、 排出口 e 2とスリット部との間をつなぐようにしている。 The suction port h8a is used for supplying the powder material mixed with air discharged from the discharge port e2 to the slit portion 32 of the powder material application device 3D for the upper punch. In order to prevent the powder material mixed with air discharged from the discharge port e2 from being sucked from the bow I port h5 when sucking the suction means (not shown: :) in step 2, the lower punch The powder material coating device 4D is provided through the through hole h8, which is provided so that the suction port h5 does not conduct. e2 and the slit are connected.
尚、 この粉体材料の塗布装置 13Dでも、 図 28に示すように、 排出口 e 2と、 吸引口 h 5との間の距離 L (e 2-h5) を、 少なくとも、 、曰- 22の直径 D 22 に比べ、 長くなるようにしている。 In addition, in this powder material coating apparatus 13D, as shown in FIG. 28, the distance L (e2-h5) between the discharge port e2 and the suction port h5 is set to at least -22 It is made longer than the diameter D22.
即ち、 この下杵用の粉体材料の塗布装置 4 Dでも、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5を、 少なくとも、 排出口 e 2が設けられている位置から、 回転テ一 ブリレ 21に設けられる、 複数の臼 22 · · 'の各々の直径 D 22より、 離れた位 置に設けている (L (e 2-h5) >D 22) 。 That is, in the powder material applying device 4D for the lower punch, the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. The plurality of dies 22... Provided on the table 21 are provided at positions separated from the diameter D 22 of each of the dies 22 (L (e 2 −h 5)> D 22).
従って、 この下杵用の粉体材料の塗布装置 4 Dでは、 下杵 24の上面 S 24及 び曰 22の内周壁面 S 22に塗布された粉体材料 (この例では、 滑沢剤粉末 L) の中、 下杵 24の上面 S 24及び曰 22の内周壁面 S 22にとつて余分な粉体材 料 (この例では、 滑沢剤粉末 L) を、 曰 22内に所定の位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける場 所 (即ち、 排出口 e 2) とは、 曰 22を介して、 導通しない場所で、 吸引除去す るようにしているので、 曰 22内に所定の位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける条件に影響を与 えることなく、 下杵 24の上面 S 24及び曰 22の内周壁面 S 22に塗布された 粉体材料 (この例では、 滑沢剤粉末 L) の中、 下杵 24の上面 S 24及び臼 22 の内周壁面 S 22にとつて余分な粉体材料 (この例では、 滑沢剤粉末 L) を、 吸 引除去することができる。 Accordingly, in the powder material applying apparatus 4D for the lower punch, the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 (in this example, the lubricant powder In L), extra powder material (in this example, lubricant powder L) is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 at a predetermined position in the lower 22. A place where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted up to (i.e., the discharge port e 2) However, since suction removal is performed, the condition that the powder material dispersed in the air current of the air pulsation wave is directly blown on the upper surface S 24 of the lower punch 24 inserted to a predetermined position in the inside 22 is affected. The powder material (in this example, lubricant powder L) applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the lower punch 24, Excess powder material (in this example, lubricant powder L) can be sucked and removed from the inner peripheral wall S22 of S24 and the mortar 22.
更に、 この下杵用の粉体材料の塗布装置 4 Dでは、 排出口 e 2と、 導管 h8の 開口部 h 8 aとの間の距離 L (e 2 -h8 a) を、 臼 22の直径 D 22に比べ、 短かくし (L (Θ 2-h8 a) く D 22) 、 排出口 e 2と開口部 h 8 aとの間が、 曰 22を介して、 導通するようにし、 排出口 e 2から、 正圧の空気脈動波ととも に、 噴霧された粉体材料中、 曰 22の内周壁面 S 22や、 下杵 24の上面 S 24 にとつて、 余分な粉体材料 (この例では、 滑沢剤粉末 L) が、 導管 h 8を通って、 長溝 D 2へ誘導されるようにしている。 Further, in the powder material application device 4D for the lower punch, the distance L (e 2 -h8 a) between the outlet e 2 and the opening h 8 a of the conduit h8 is determined by the diameter of the mill 22. Compared to D22, the length is shorter (L (Θ 2-h8a) D22), and the connection between the outlet e2 and the opening h8a is made to be conductive through 22 and the outlet e From Fig. 2, with the positive pressure air pulsation wave, in the sprayed powder material, for the inner peripheral wall S22 of 22 and the upper surface S24 of the lower punch 24, extra powder material (in this example) In this example, the lubricant powder L) is guided to the long groove D2 through the conduit h8.
また、 排出口 e 2から正圧の空気脈動波とともに噴霧された粉体材料が、 開口 部 h8 aから、 導管 h 8内へ誘導され易いように、 開口部 h 8 aと吸引口 h 5と の間の距離 L (h8 a-h5) を、 少なくとも、 臼 22の直径 D 22に比べ、 長 くして、 開口部 h8aと吸引口 h5とが、 曰 22を介して、 導通することがない ようにしている (L (h8 a-h5) >D 22)。 The opening h8a and the suction port h5 are also provided so that the powder material sprayed with the positive pressure air pulsating wave from the outlet e2 is easily guided into the conduit h8 from the opening h8a. The distance L (h8 a-h5) between them is at least longer than the diameter D22 of the mortar 22, so that the opening h8a and the suction port h5 do not conduct through the 22. (L (h8 a-h5)> D 22).
また、 図 29は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す 平面図であり、 又、 図 30は、 図 29中、 XXX— XXX線に従う概略的な断面 図である。 FIG. 29 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention. FIG. 30 is a schematic sectional view taken along line XXX-XXX in FIG. It is.
尚、 この粉体材料の塗布装置 13 Eでは、 接続口 e 9が、 吸引口 T 4 aに接続 されており、 接続口 e 9には、 第 1の吸引手段 11を接続するようにしてあり、 第 1の吸引手段 11を駆動すると、 吸引口 T4aに、 吸引口 T4a内に向かう、 吸引雰囲気の気流が発生するようにしている。 In the powder material application device 13E, the connection port e9 is connected to the suction port T4a, and the connection port e9 is connected to the first suction means 11. When the first suction means 11 is driven, an airflow of a suction atmosphere is generated at the suction port T4a toward the inside of the suction port T4a.
また、 図 30では、 図面の理解を容易とするために、 図 21中に表されている、 2本の上杵 23、 23の中、 一方の上杵 23を想像線で示している。 In FIG. 30, one of the two upper punches 23, 23 shown in FIG. 21 is shown by an imaginary line to facilitate understanding of the drawing.
この粉体材料の塗布装置 13 Eは、 粉体材料の塗布装置 13 Dを構成する下杵 用の粉体材料の塗布装置 4 Dの、 排出口 e 2の上流側 (回転テーブル 21の回転 方向の逆方向) に、 更に、 第 3の吸引手段 (図示せず。 ) に接続される成形材料 吸引口 h6 aを設けている。 This powder material coating device 13E is an upstream side of the discharge port e2 of the powder material coating device 4D for the lower punch, which constitutes the powder material coating device 13D (the rotation direction of the rotary table 21). In the direction opposite to the above, a molding material suction port h6a connected to the third suction means (not shown) is further provided.
この粉体材料の塗布装置 13Dは、 下杵用の粉体材料の塗布装置 4 Dに、 回転 テ一ブル 21の回転方向に順方向の位置に、 上杵用の粉体材料の塗布装置 4 Dが 接続された構造になっている。 The powder material coating device 13D is connected to the powder material coating device 4D for the lower punch and the powder material coating device 4 for the upper punch at a position in the forward direction in the rotation direction of the rotary table 21. D is connected.
下杵用の粉体材料の塗布装置 4 Dの回転テーブル 21に対向する側の表面 S 4 aには、 回転テーブル 21の回転方向に順方向 (上流側から下流方向) に、 排出 口 e2、 吸引口 h8a、 第 2の吸引手段 (図示せず。 ) の吸引口 h 5が設けられ ている。 The surface S 4 a of the powder material application device 4 D for the lower punch facing the rotary table 21 is provided with a discharge port e 2, in the forward direction (from the upstream side to the downstream side) in the rotating direction of the rotary table 21. A suction port h8a and a suction port h5 for second suction means (not shown) are provided.
吸引口 h 8 aは、 排出口 e 2より排出された、 空気に混和された粉体材料を、 上杵用の粉体材料の塗布装置 3Dのスリット部 32へ供給する際に、 第 2の吸引 手段 (図示せず。 ) を吸引した際に、 排出口 e 2より排出された、 空気に混和さ れた粉体材料が、 引口 h5から吸引されないように、 下杵用の粉体材料の塗布装 置 4D内を、 吸引口 h5は導通しないように設けた、 貫通孔 h8により、 排出口 e 2とスリット部との間をつなぐようにしている。 この粉体材料の塗布装置 13Eでは、 この装置 13 Eを構成する下杵用の粉体 材料の塗布装置 4Eの、 滑沢剤粉末 Lを排出する排出口 e 2の前段部に、 成形材 料吸引口 h 6 aを有する第 3の吸引手段 (図示せず。 ) を設け、 滑沢剤粉末 Lを、 臼 22 · · ·の各々噴霧する前に、 曰 22 · · ·の各々の内周壁面 S 22 · · . 及び下杵 24 · · 'の各々の上面 S 24 · · 'を清浄しているので、 前工程で使 用した成形材料 Mや滑沢剤粉末 Lが、 次工程で製造される錠剤 t · · ·中に混入 することがないので、 錠剤 t · · 'を連続的に製造しても、 錠剤 t · · '間で、 滑沢剤粉末 Lの使用量等に不均一を生じない。 これにより、 同じ規格の錠剤 t · • ·を連続的に製造できる。 The suction port h8a is used to supply the powder material mixed with air discharged from the discharge port e2 to the slit 32 of the powder material application device 3D for the upper punch. When sucking the suction means (not shown), the powder material mixed with the air discharged from the discharge port e2 is not sucked from the inlet port h5 so that the powder material for the lower punch is used. In the coating device 4D, the suction port h5 is provided so as not to conduct, and the through hole h8 connects the discharge port e2 and the slit portion. In the powder material coating apparatus 13E, a molding material is provided at the front of the discharge port e2 for discharging the lubricant powder L of the powder material coating apparatus 4E for the lower punch constituting the apparatus 13E. A third suction means (not shown) having a suction port h 6 a is provided, and before the lubricant powder L is sprayed on each of the dies 22, the inner circumference of each of the dies 22 is described. Since the upper surface S 24 ··· of the wall S 22 ··· and the lower punch 24 ·· 'is cleaned, the molding material M and lubricant powder L used in the previous process are produced in the next process.錠 剤 · 'し て も し て も し て も し て も し て も し て も し て も し て も し て も し て も し て も し て も. Does not occur. This enables continuous production of tablets of the same standard.
尚、 この粉体材料の塗布装置 13 Eでも、 図 30に示すように、 排出口 e2と、 吸引口 h5との間の距離 L (e 2-h5) を、 少なくとも、 臼 22の直径 D 22 に比べ、 長くなるようにしている。 In addition, in this powder material coating apparatus 13E, as shown in FIG. 30, the distance L (e2-h5) between the discharge port e2 and the suction port h5 is set to at least the diameter D22 of the die 22. It is made longer than.
即ち、 この下杵用の粉体材料の塗布装置 4 Dでも、 第 2の吸引手段 (図示せず。 ) の吸引口 h5を、 少なくとも、 排出口 e 2が設けられている位置から、 回転テ一 ブル 21に設けられる、 複数の曰 22 · · 'の各々の直径 D 22より、 離れた位 置に設けている (L (e2-h5) >D22)。 That is, even in the powder material applying device 4D for the lower punch, the suction port h5 of the second suction means (not shown) is rotated at least from the position where the discharge port e2 is provided. It is provided at a position distant from the diameter D22 of each of a plurality of sayings 22 · · 'provided on one bull 21 (L (e2-h5)> D22).
従って、 この下杵用の粉体材料の塗布装置 4 Dでは、 下杵 24の上面 S 24及 び曰 22の内周壁面 S 22に塗布された粉体材料 (この例では、 滑沢剤粉末 L) の中、 下杵 24の上面 S 24及び曰 22の内周壁面 S 22にとつて余分な粉体材 料 (この例では、 滑沢剤粉末 L) を、 曰 22内に所定の位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける場 所 (即ち、 排出口 e2) とは、 曰 22を介して、 導通しない場所で、 吸引除去す るようにしているので、 臼 22内に所定の位置まで挿入された下杵 24の上面 S 24に、 空気脈動波の気流に分散した粉体材料を直接吹き付ける条件に影響を与 えることなく、 下杵 24の上面 S 24及び臼 22の内周壁面 S 22に塗布された 粉体材料 (この例では、 滑沢剤粉末 L)の中、 下杵 24の上面 S 24及び曰 22 の内周壁面 S 22にとつて余分な粉体材料 (この例では、 滑沢剤粉末 L) を、 吸 引除去することができる。 Accordingly, in the powder material applying apparatus 4D for the lower punch, the powder material applied to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 (in this example, the lubricant powder In L), extra powder material (in this example, lubricant powder L) is added to the upper surface S24 of the lower punch 24 and the inner peripheral wall S22 of the lower punch 24 at a predetermined position in the lower 22. A place where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface S 24 of the lower punch 24 inserted up to (i.e., the discharge port e2) is a place where it does not conduct through 22 Since suction removal is performed, the condition that the powder material dispersed in the air current of the air pulsating wave is directly sprayed on the upper surface S 24 of the lower punch 24 inserted to the predetermined position in the die 22 is affected. The upper surface S of the lower punch 24 in the powder material (in this example, the lubricant powder L) applied to the upper surface S 24 of the lower punch 24 and the inner peripheral wall S 22 of the die 22 Excess powder material (in this example, lubricant powder L) can be sucked and removed on the inner peripheral wall S22 of No. 24 and No. 22.
更に、 この下杵用の粉体材料の塗布装置 4 Dでは、 排出口 e 2と、 導管 h8の 開口部 h 8 aとの間の距離 L (e 2-h8 a) を、 臼 22の直径 D 22に比べ、 短かくし (L (e2— h8a) く D22)、 排出口 e 2と開口部 h 8 aとの間が、 臼 22を介して、 導通するようにし、 排出口 e 2から、 正圧の空気脈動波ととも Further, in the powder material application device 4D for the lower punch, the discharge port e2 and the conduit h8 are connected. The distance L (e2-h8a) between the opening h8a and the diameter D22 of the mortar 22 is made shorter (L (e2—h8a) less D22), and the outlet e2 and the opening h 8a through the mortar 22 so as to conduct, and from the discharge port e2 together with the air pulsation wave of positive pressure
ヽ' ヽ '
に、 噴霧された粉体材料中、 臼 22の内周壁面 S 22や、 下杵 24の上面 S 24 にとつて、 余分な粉体材料 (この例では、 滑沢剤粉末 L) が、 導管 h 8を通って、 長溝 D 2へ誘導されるようにしている。 In the sprayed powder material, extra powder material (in this example, lubricant powder L) is passed through the conduit for the inner peripheral wall S22 of the mortar 22 and the upper surface S24 of the lower punch 24. Through h8, it is guided to the long groove D2.
また、 排出口 e 2から正圧の空気脈動波とともに噴霧された粉体材料が、 開口 部 h8aから、 導管 h 8内へ誘導され易いように、 開口部 h 8 aと吸引口 h 5と の間の距離 L (h8 a-h5) を、 少なくとも、 曰 22の直径 D 22に比べ、 長 くして、 開口部 h8 aと吸引口 h5 が、 曰 22を介して、 導通することがない ようにしている (L (h8 a-h5) >D 22)。 Also, the opening h8a and the suction port h5 are connected so that the powder material sprayed with the positive pressure air pulsation wave from the outlet e2 is easily guided into the conduit h8 from the opening h8a. The distance L (h8 a-h5) between them should be at least longer than the diameter D22 of 22 so that the opening h8a and the suction port h5 do not conduct through 22. (L (h8 a-h5)> D 22).
尚、 発明の実施の形態 1に示した、 上杵用の粉体材料の塗布装置 3は、 単に、 本発明を説明するために好ましい例を説明したに過ぎず、 種々の変形例がある。 そのような上杵用の粉体材料の塗布装置としては、 スリヅト部 32の形状を、 粉 体材料の塗布装置 1· 3 Aと同様、 ジグザグ形状にしたものや、 スリット部 32の 上方に、 粉体材料の塗布装置 13 Bと同様、 メッシュ手段 14を設けたものや、 スリット部 32の形状をジグザグ形状にし、 更に、 その上方に、 メッシュ手段 1 4を設けたものも、 本発明に係る上杵用の粉体材料の塗布装置に含まれる。 Note that the powder material application device 3 for the upper punch shown in the first embodiment of the invention is merely a preferable example for explaining the present invention, and there are various modifications. As the applicator for the powder material for the upper punch, the slit portion 32 is formed in a zigzag shape, similarly to the powder material applicator 1.3A, or above the slit portion 32. Similar to the powder material coating apparatus 13B, the present invention includes a device provided with the mesh means 14 and a device provided with the slit means 32 in a zigzag shape and further provided with the mesh means 14 above the slit means 32 according to the present invention. It is included in the powder material application device for the upper punch.
また、 発明の実施の形態 2に示した、 粉体材料の塗布装置 13、 13 A 13 B、 13C、 13Eも、 単に、 本発明を説明するために好ましい例を説明したに 過ぎず、 種々の変形例がある。 In addition, the powder material coating apparatuses 13, 13A, 13B, 13C, and 13E shown in the second embodiment of the present invention merely describe preferred examples for describing the present invention, and There are variations.
そのような粉 料の塗布装置としては、 スリット部 32の形状を、 粉体材料 の塗布装置 13 Aと同様、 ジグザグ形状にし、 更に、 その上方に、 メッシュ手段 14を設けたものも、 本発明に係る上杵用の粉 料の塗布装置に含まれる。 更に、 本発明に係る外部滑沢式打錠機として、 発明の実施の形態 1では、 上杵 用の粉体材料の塗布装置と、 下杵用の粉体材料の塗布装置との双方が設けられた 例について説明したが、 本発明に係る外部滑沢式打錠機には、 上杵用の粉体材料 の塗布装置又は下杵用の粉体材料の塗布装置の少なくとも一方を含むものも含ま れる。 次に、 本発明を実験例に基づいて、 説明する。 As such a powder coating device, the slit portion 32 may have a zigzag shape similarly to the powder material coating device 13A, and a mesh means 14 may be provided above the slit portion 32 of the present invention. It is included in the powder applicator for upper punches according to the above. Further, as the external lubricating tableting machine according to the present invention, in Embodiment 1 of the present invention, both an applicator for the powder material for the upper punch and an applicator for the powder material for the lower punch are provided. However, the external lubricating tableting machine according to the present invention may include at least one of an applicator for a powder material for an upper punch and an applicator for a powder material for a lower punch. included. Next, the present invention will be described based on experimental examples.
(分散法別の経時的な噴霧量変化の観察試験) (Observation test of change of spray amount over time by dispersion method)
(実験例 1) (Experimental example 1)
図 7に示す粉体材料の吐出装置 5を用い、 ホッパー 51内に、 粉体材料 (この 例では、 ステアリン酸マグネシウム粉末 (局方品) ) を貯留し、 分散室 55内に、 図 12に示す空気脈動波発生装置 8を用い、 供給空気量が 25ニュートン · リツ トル/分 (N · 1/min) (流量制御装置 21からの出力値) 、 供給空気圧が 0. 2Mpaとし、 振動数を 20ヘルヅ (Hz) の空気脈動波を発生させ、 排出 口 55bより排出される粉体材料の量 (噴霧量) の変化を絰時的に測定した。 (比較例 1 ) A powder material (magnesium stearate powder (in this example, powder of local government)) is stored in the hopper 51 using the powder material discharge device 5 shown in FIG. 7, and is stored in the dispersion chamber 55 in FIG. Using the air pulsation wave generator 8 shown in the figure, the supply air amount is 25 Newton liters / minute (N · 1 / min) (output value from the flow control device 21), the supply air pressure is 0.2Mpa, and the vibration frequency is An air pulsation wave of 20 hertz (Hz) was generated, and the change in the amount (spray amount) of the powder material discharged from the outlet 55b was measured temporarily. (Comparative Example 1)
比較例 1として、 粉体材料の吐出装置 5の分散室 55に、 空気脈動波導入口 5 5 aを分散室 55の中心線を通る方向に設け、 分散室 55内に、 空気脈動波を旋 回流にしないようにする以外は、 実験例 1と同様の実験を行い、 排出口 55bよ り排出される粉体材料の量 (噴霧量) の変化を絰時的に測定した。 As Comparative Example 1, an air pulsation wave inlet 55 a was provided in the dispersion chamber 55 of the powder material discharge device 5 in a direction passing through the center line of the dispersion chamber 55, and the air pulsation wave was swirled in the dispersion chamber 55. The same experiment as in Experimental Example 1 was performed except that the amount was not changed, and the change in the amount of the powder material (spray amount) discharged from the discharge port 55b was temporarily measured.
なお、 実験例 1及び比較例 1では、 各々の試験の間、 レベルセンサ一 56の検 出値に基づいて、 各々の粉体材料貯留室 53、 53内に貯留する粉体材料の弾性 膜体 3からの高さは、 30mm±2. 5 mmにコントロールした。 In Experimental Example 1 and Comparative Example 1, during each test, the elastic film of the powder material stored in each of the powder material storage chambers 53, 53 was measured based on the detection value of the level sensor 56. The height from 3 was controlled to 30 mm ± 2.5 mm.
結果を表 1及び図 31に示す。 The results are shown in Table 1 and FIG.
【表 1】 别の絰時的な噴霧置 化 [Table 1] Temporary spraying of 别
尚、 表 1及び図 3 1中、 新法は、 実験例 1 (本発明に係る粉体材料の吐出装置 5を用いた場合) の実験結果を、 また、 従来法は、 比較例 1の実験結果を示して いる。 In Table 1 and FIG. 31, the new method shows the experimental results of Experimental Example 1 (when the powder material discharge device 5 according to the present invention is used), and the conventional method shows the experimental results of Comparative Example 1. Is shown.
また、 表 1中、 噴霧量は、 1分間に、 排出口 5 5 bより噴霧される粉体材料の 重量 (mg) を示しており、 CVは、 そのパラヅキ (%) を示している。 また、 Rは、 最大値と最小値の差を示している。 Also, in Table 1, the spray amount indicates the weight (mg) of the powder material sprayed from the outlet 55b in one minute, and the CV indicates the ratio (%). R indicates the difference between the maximum value and the minimum value.
表 1及び図 3 1の結果より、 新法 (実験例 1 ) の方が、 従来法 (比較例 1 ) に 比べ、 排出される粉体材料の量 (噴霧量) のパラツキが小さいことが明らかにな つた (新法のバラヅキく従来法のバラヅキ) 。 From the results shown in Table 1 and Fig. 31, it is clear that the new method (Experimental Example 1) has less variation in the amount of powder material discharged (spray amount) than the conventional method (Comparative Example 1). Natsuta (Variation under the new law and variation under the conventional method).
以上により、 新法は、 常に一定量の粉 料を、 連続して、 安定して、 排出口 4 bより排出できることが明らかになった。 Based on the above, the new law requires that a certain amount of powder be continuously and stably It became clear that it could be discharged from 4 b.
また、 新法では、 分散室 5 5内において、 弾性膜体 5 4の孔部 (スリット) 5 In addition, according to the new method, the holes (slits) 5
4 aより排出された粉体材料は、 旋回流となっている空気脈動波に均一に分散し ていた。 The powder material discharged from 4a was uniformly dispersed in the swirling air pulsating wave.
一方、 従来法では、 分散室 5 5内において、 弾性莫体 5 4の孔部 (スリヅト) On the other hand, according to the conventional method, in the dispersing chamber 55, a hole (slit) of the elastic elastic body 54 is formed.
5 4 aより排出された粉体材料は、 空気脈動波に均一に分散していなかった。 以上により、 新法では、 排出口 5 5 bより排出される粉体材料の粒径が、 従来 法の排出口 1 5 5 bより排出される粉体材料の粒径に比べ、 均一化していること が明らかになった。 The powder material discharged from 54a was not uniformly dispersed in the air pulsation wave. As described above, in the new method, the particle size of the powder material discharged from the outlet 55b is more uniform than the particle size of the powder material discharged from the outlet 55b in the conventional method. Was revealed.
(噴面高さの違いによる噴霧量変化の観察試験) (Observation test of change in spray amount due to difference in jet height)
(実験例 2 ) (Experimental example 2)
図 2 0に示す粉体材料の吐出装置 1 3を用い、 また、 ホッパー手段 5 1に、 粉 体材料 (この例では、 ステアリン酸マグネシウム粉末 (局方品) ) を貯留し、 こ の試験の間、 レベルセンサー 5 6の検出値に基づいて、 粉体材料切出手段 (粉体 材料切出弁) 5 2を開閉制御し、 粉体材料貯留室 5 3内に貯留する粉体材料の弾 性膜体 5 4からの高さを、 常に、 1 0 mm± 2 . 5 mmにコントロールしつつ、 図 1 2に示す空気脈動波発生装置 8を用い、 供給空気量が 2 5ニュートン · リツ トル/分 (N . 1 /m i n ) (流量制御装置 1 2からの出力値) 、 供給空気圧が 0 . 2 M p aとし、 振動数を 2 0ヘルツ (H z ) の空気脈動波を発生させ、 排出 口 5 5 bより排出される粉体材料の量 (噴霧量) の変化を経時的に測定した。 (実験例 3 ) A powder material (magnesium stearate powder (pharmaceutical product in this example)) is stored in the hopper means 51 using the powder material discharging device 13 shown in FIG. The powder material extraction means (powder material extraction valve) 52 is controlled to open and close based on the detection values of the level sensor 56 and the powder material stored in the powder material storage chamber 53. While constantly controlling the height from the permeable membrane 54 to 10 mm ± 2.5 mm, using the air pulsation wave generator 8 shown in Fig. 12, the supply air volume is 25 Newton-liter. / Min (N.1 / min) (output value from the flow controller 12), supply air pressure is 0.2 Mpa, and a frequency of 20 Hz (Hz) is generated and discharged. Changes in the amount (spray amount) of the powder material discharged from the mouth 55b were measured over time. (Experimental example 3)
実験例 2とは、 弾性莫体 5 4からの高さを、 常に、 7 0 mm土 2 . 5 mmのコ ントロールする以外は、 同様に実験を行い、 排出口 7 4 bより排出される粉 料の量 (噴霧量) の変化を経時的に測定した。 Experimental example 2 is the same as the experiment except that the height from the elastic block 54 was always controlled to 70 mm and the soil to 2.5 mm, and the powder discharged from the discharge port 74 b was used. Changes in the amount of spray (spray amount) were measured over time.
結果を表 2及び図 3 2に示す。 【表 2】 The results are shown in Table 2 and FIG. [Table 2]
表 2及び図 3 2より、 同じ装置及び同じ空気脈動波を用いた場合であっても、 弾性膜体 5 4の孔部 (スリット) 5 4 aより排出された粉体材料の量には違いが あることが明らかになった。 From Table 2 and Fig. 32, the amount of powder material discharged from the hole (slit) 54 a of the elastic membrane 54 differs even when the same device and the same air pulsating wave are used. It became clear that there was.
これにより、 常に一定量の粉体材料を、 連続的に、 排出口 5 5 bより排出する には、 粉体材料貯留室 2内に貯留する粉体材料の弾性膜体 5 4からの高さを、 常 に、 概ね一定に維持するのが好ましいことが明らかになった。 As a result, the height of the powder material stored in the powder material storage chamber 2 from the elastic membrane 54 can be constantly discharged from the discharge port 55 b in order to discharge a constant amount of the powder material. It has been found that it is always preferable to keep the value approximately constant.
(連続打錠試験) (Continuous tableting test)
(実験例 4 ) (Experimental example 4)
実験例 3の条件で、 図 1 7に示す外部滑沢式打錠機 1 Bを用いて、 乳糖顆粒に 結合剤を適量添加し、 その後、 均一に混練したものを、 刻印 (製品コード及び会 社コード) 並びに分割線を有する上杵及び下杵を用い、 連続打錠し、 製造される 錠剤の打錠障害 (ステッキング、 キヤヅビング、 ラミネ一ティング) を観察した。 Under the conditions of Experimental Example 3, an appropriate amount of binder was added to lactose granules using an external lubricating tableting machine 1B shown in Fig. 17 and then uniformly kneaded. Using the upper punch and the lower punch having a dividing line and continuous punching, tableting obstruction (sticking, caving, laminating) of the manufactured tablets was observed.
(比較例 2 ) (Comparative Example 2)
比較例 2は、 特開昭 5 6 - 1 4 0 9 8号公報に記載の外部滑沢打錠機と同様の 装置を用いて錠剤を連続打錠した例を示す。 Comparative Example 2 shows an example in which tablets were continuously tableted using the same device as the external lubricating tableting machine described in JP-A-56-14098.
実験例 4で使用した、 乳糖顆粒に結合剤を適量添加し、 その後、 均一に混練し たものを、 滑沢剤塗布室で、 下杵が所定の位置まで挿入した状態にされた臼の下 杵の上面に、 ステアリン酸マグネシウム粉末を適量載置し、 その後、 組となる、 曰、 下杵及び上杵を、 散布室内に収容し、 ノズルより、 空気を所定の圧力で噴霧 して、 滑沢剤塗布室で、 下杵の上面に載置したステアリン酸マグネシウム粉末を 吹き飛ばし、 下杵の上面、 上杵の下面、 及び、 下杵が所定の位置まで挿入した状 態にされた臼の内周壁面に、 ステアリン酸マグネシウム粉末を塗布し、 以上のよ うにして、 下面にステアリン酸マグネシウム粉末が塗布された上杵、 上面にステ ァリン酸マグネシウム粉末が塗布された下杵、 内周壁面にステアリン酸マグネシ ゥム粉末が塗布された臼を用いて、 連続打錠を試みた。 An appropriate amount of a binder was added to the lactose granules used in Experimental Example 4 and then uniformly kneaded. Then, in a lubricant application chamber, a lower punch was inserted into a predetermined position under a mill. An appropriate amount of magnesium stearate powder is placed on the upper surface of the punch, and then, as a set, the lower punch and the upper punch are housed in the spraying chamber, and air is sprayed from the nozzle at a predetermined pressure to smooth out. In the lubricant application chamber, the magnesium stearate powder placed on the upper surface of the lower punch was blown off, and the upper surface of the lower punch, the lower surface of the upper punch, and the inside of the mill with the lower punch inserted to the specified position Magnesium stearate powder is applied to the peripheral wall, and the upper punch with magnesium stearate powder applied to the lower surface, the lower punch with magnesium stearate powder applied to the upper surface, and the inner peripheral wall as described above. Magnesium stearate Continuous tableting was attempted using a die coated with gum powder.
実験例 4では、 5時間連続打鍵しても、 打錠障害が観察されなかったのに対し、 比較例 2では、 下杵の上面、 上杵の下面、 及び、 下杵が所定の位置まで挿入した 状態にされた臼の内周壁面に、 ステアリン酸マグネシウム粉末を塗布する条件を 種々変化させたが、 いずれも、 1時間以内に、 打錠障害がかなりの頻度で観察さ れた。 In Experimental Example 4, no tableting trouble was observed even after 5 hours of continuous keying, whereas in Comparative Example 2, the upper surface of the lower punch, the lower surface of the upper punch, and the lower punch were inserted to the predetermined positions. Various conditions were applied to apply the magnesium stearate powder to the inner peripheral wall of the mortar in the above state, but in all cases, tableting failure was observed quite frequently within one hour.
以上により、 本発明に係る外部滑沢式打錠機 1 Bは、 刻印等の複雑な凹凸形状 を有する錠剤であっても、 成形材料中に、 滑沢剤を添加することなく、 連続打錠 できることが、 明らかになった。 ' As described above, the external lubricating tableting machine 1B according to the present invention provides continuous tableting without adding a lubricant to the molding material, even if the tablet has a complex uneven shape such as stamping. It became clear what we could do. '
また、 外部滑沢式打錠機 1 Bに代えて、 外部滑沢式打錠機 1、 1 A等を用い、 上記と同様の試験を行ったが、 実験により、 外部滑沢式打錠機 1 Bと同様の効果 を奏することが、 明らかになった。 In addition, the same test as above was conducted using the external lubricating tablet press 1, 1A, etc. instead of the external lubricating tablet press 1B. It became clear that the same effect as 1B was achieved.
また、 図 3 3は、 本発明に係る粉体材料の塗布装置の他の一例を概略的に示す 平面図である。 FIG. 33 is a plan view schematically showing another example of the powder material coating apparatus according to the present invention.
この粉体材料の塗布装置 1 3 Fは、 図 2 0に示す、 粉体材料の塗布装置 1 3を 構成する、 上杵用の粉体材料の塗布装置 3 Bの代わりに、 上杵用の粉体材料の塗 布装置 3 Fが用いられている以外は、 粉 料の塗布装置 1 3と同様の構成を備 える。 、- この粉体材料の塗布装置 1 3 Fは、 図 3 3に示すように、 上杵用の粉体材料の 塗布装置 3 Bのスリット部の代わりに、 上杵収容溝 3 1の底面に、 複数の上杵 2 3 · · ·の回転軌道に沿って、 上杵収容溝 3 1内を移動する複数の上杵 2 3 · · •の各々の下面 S 2 3 · · ·に、 空気脈動波の気流に分散された粉体材料 (この 例では、 滑沢剤粉末 L ) を噴霧する、 複数の噴射孔 h s · · 'を配置している。 この粉体材料の塗布装置 1 3 Fでは、 上杵収容溝 3 1の底面に、 複数の上杵 2 3 · · ·の回転軌道に沿って、 上杵収容溝 3 1内を移動する複数の上杵 2 3 . · •の各々の下面 S 2 3 · · ·に、 空気脈動波の気流に分散された粉体材料 (この 例では、 滑沢剤粉末 L ) を噴霧する、 複数の噴射孔 h s · · ·を配置したので、 粉体材料 (この例では、 滑沢剤粉末 L ) が、 複数の噴射孔 h s · · 'の各々から 噴霧される際に、 気流に、 ある種の整流効果が得られる。 This powder material coating device 13F is a powder material coating device 13 shown in FIG. The same as the powder applicator 13 except that the powder material applicator 3F for the upper punch is used instead of the powder applicator 3B for the upper punch that constitutes It has a configuration. As shown in Fig. 33, instead of the slit of the powder material coating device 3B for the upper punch, the powder material coating device 13F is provided on the bottom surface of the upper punch receiving groove 31 as shown in Fig. 33. The air pulsation is generated on the lower surface S2 3 of each of the plurality of upper punches 2 3 moving along the rotation path of the upper punches 2 3 A plurality of injection holes hs are arranged for spraying a powder material (in this example, lubricant powder L) dispersed in a wave current. In the powder material coating device 1 3F, a plurality of upper punches 23 move along the rotation path of the upper punches 2 3 on the bottom surface of the upper punch receiving grooves 31. A plurality of injection holes for spraying a powder material (in this example, lubricant powder L) dispersed in the air pulsating wave air flow on each lower surface S 23 of the upper punch 23. hs ..., the powder material (in this example, lubricant powder L) is sprayed from each of the plurality of injection holes hs Is obtained.
これにより、 重力との関係で、 粉体材料 (この例では、 滑沢剤粉末 L ) が付着 し難い、 上杵 2 3 · · ·の各々の下面 S 2 3 ■ · ·に、 粉体材料 (この例では、 滑沢剤粉末 L ) が、 均一に塗布される。 This makes it difficult for the powder material (in this example, the lubricant powder L) to adhere due to the relationship with gravity, so that the lower surface S 2 3 (In this example, the lubricant powder L) is applied uniformly.
また、 上杵収容溝 3 1の底面に、 複数の噴射孔 h s · · ·を配置する場合には、 複数の噴射孔 h s ·' · 'は、 一列に設けてもよいが、 2列以上設けるようにして もよい。 In the case where a plurality of injection holes hs are arranged on the bottom surface of the upper punch receiving groove 31, the plurality of injection holes hs You may do so.
また、 図 3 3に示すように、 複数の噴射孔 h s · · ·を、 3列に配置するよう な場合にあっては、 中心列に設ける噴射孔 h s · · ·の各々と、 その両側の列に 設けられる噴射孔 h s · · 'の各々とは、 互い違いに設けると、 スリット部 3 2 をジグザグに設けた場合と、 同様の効果を得ることもできる。 産業上の利用可能性 Further, as shown in FIG. 33, when a plurality of injection holes hs are arranged in three rows, each of the injection holes hs provided in the center row and both sides of the injection holes hs are provided. If the injection holes hs... Provided in the rows are alternately provided, the same effect as when the slit portions 32 are provided in a zigzag manner can be obtained. Industrial applicability
以上、 詳細に説明したように、 請求項 1に記載の粉体材料の塗布方法では、 粉 体材料が付着堆積し易い、 下杵の上面には、 空気脈動波に混和された粉体材料を 直接吹き付けることで、 余分に堆積している粉 ^料を吹き飛ばすことにより、 下杵の上面に粉体材料が余分に付着堆積しないようにし、 下杵の上面に、 粉体材 料を均一に塗布するようにしている。 As described above in detail, in the method for applying a powder material according to claim 1, the powder material mixed with the air pulsating wave is applied to the upper surface of the lower punch, where the powder material is easily attached and deposited. By directly spraying, by blowing off the powder that has accumulated extra, Excessive powder material is prevented from adhering and accumulating on the upper surface of the lower punch, and the powder material is uniformly applied to the upper surface of the lower punch.
また、 下杵の上面に比べ、 粉体材料が付着し難い、 下杵が所定の位置まで挿入 された曰の内周壁面には、 下杵の上面から吹き飛ばされた余分な粉体材料の一部 が付着するので、 曰の内周壁面には、'下杵の上面に塗布したと概ね同じ量の粉体 材料が均一に塗布するようになる。 Also, compared to the upper surface of the lower punch, the powder material is less likely to adhere, and the inner peripheral wall where the lower punch has been inserted to a predetermined position has excess powder material blown off from the upper surface of the lower punch. Because the part adheres, the same amount of powder material as that applied to the upper surface of the lower punch is uniformly applied to the inner peripheral wall surface.
且つ、 下杵の上面及び曰の内周壁面において塗布されなかった粉体材料は、 次 の組を構成する上杵の下面に、 空気に混和し、 分散され、 流動化した状態で送ら れるが、 上杵の下面へは、 上杵の下面に対し、 下方から上方に向かう気流に、 粉 体材料を乗せて、 時間をかけて付着するようにしているので、 重力との関係で粉 体材料が付着し難い、 上杵の下面にも、 下杵の上面や曰の内周壁面に塗布したと 概ね同じ量の粉体材料が均一に塗布するようになる。 The powder material not applied on the upper surface of the lower punch and the inner peripheral wall is mixed with air, dispersed, and sent to the lower surface of the upper punch constituting the next set in a fluidized state. On the lower surface of the upper punch, the powder material is put on the airflow from the lower side to the upper side with respect to the lower surface of the upper punch, so that the powder material adheres over time, so that the powder material is related to gravity. Approximately the same amount of powder material as that applied to the upper surface of the lower punch and the inner peripheral wall is said to be uniformly applied to the lower surface of the upper punch, which is difficult to adhere to.
請求項 2に記載の粉体材料の塗布方法では、 下杵の上面及び下杵が所定の位置 まで挿入された曰の内周壁面への粉体材料の塗布と、 上杵の下面への粉体材料の 塗布とを一連の気流の流れで行うようにし、 下杵の上面及び曰の内周壁面にとつ て、 余分な粉体材料を、 上杵の下面への塗布に用いているので、 粉体材料を無駄 なく、 有効活用できる。 In the method for applying a powder material according to claim 2, the powder material is applied to the inner peripheral wall surface where the upper surface of the lower punch and the lower punch are inserted to a predetermined position, and the powder is applied to the lower surface of the upper punch. The body material is applied by a series of airflows, and extra powder material is used to apply to the lower surface of the upper punch, on the upper surface of the lower punch and on the inner peripheral wall. The powder material can be used effectively without waste.
請求項 3に記載の粉体材料の塗布方法では、 上杵の下面より上方の位置に吸引 口を有する吸引手段を設けるという簡単な構成で、 上杵の下面に、 下方から上方 に向かう気流を発生させることができる。 In the powder material applying method according to claim 3, a simple configuration in which a suction means having a suction port is provided at a position above the lower surface of the upper punch, the air flow from the lower side to the upper side is formed on the lower surface of the upper punch. Can be generated.
請求項 4に記載の粉体材料の塗布方法では、 下杵の上面及び曰の内周壁面に塗 布された粉体材料の中、 下杵の上面及び臼の内周壁面にとって余分な粉体材料を、 曰内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分散した粉 体材料を直接吹き付ける場所とは、 導通しない場所で、 吸引除去するようにして いるので、 臼内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に 分散した粉 料を直接吹き付ける条件に影響を与えることなく、 下杵の上面及 び曰の内周壁面に塗布された粉体材料の中、 下杵の上面及び曰の内周壁面にとつ て余分な粉 料を、 吸引除去することができる。 In the powder material application method according to claim 4, the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface of the die among the powder material applied to the upper surface of the lower punch and the inner peripheral wall surface of the die are described. The material is sucked and removed from the place where the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface of the lower punch inserted into the specified position inside the pier, where it does not conduct. The surface of the lower punch and the inner wall of the lower punch are not affected by the condition that the powder dispersed in the air pulsation wave is directly blown onto the upper surface of the lower punch inserted into the mortar to a predetermined position. Excess powder can be removed by suction from the applied powder material on the upper surface of the lower punch and the inner peripheral wall.
請求項 5に記載の錠剤の製造方法では、 下杵が、 曰内で最下位となる位置で、 下杵の上面及び曰の内周壁面に、 粉体材料を塗布するようにし、 成形材料を圧縮 成形する際に、 成形材料に接触する曰の内周壁面に、 万遍なく、 粉体材料を塗布 するようにしているので、 錠剤を製造する際に、 曰に成形材料が付着しない。 これにより、 ステイツキングや、 ラミネ一ティングや、 キヤヅビング等の打錠 障害を生じることなく、 錠剤を製造できるので、 錠剤の製造効率が向上する。 請求項 6に記載の錠剤の製造方法では、 請求項 1に記載の粉体材料の塗布方法 を用いて、 下杵が所定の位置まで挿入された曰の内周壁面、 上杵の下面、 及び、 下杵の上面の各々に、 粉体材料を塗布するようにし、 粉体材料が均一に塗布され た内周壁面を有する曰、 粉体材料が均一に塗布された下面を有する上杵、 及び、 粉体材料が均一に塗布された上面を有する下杵を、 順次、 使用して、 成形材料を 圧縮成形して、 錠剤を製造するようにしている。 In the tablet manufacturing method according to claim 5, the lower punch is located at the lowest position in The powder material is applied to the upper surface of the lower punch and the inner peripheral wall, and when the molding material is compression-molded, the powder material is uniformly applied to the inner peripheral wall that comes into contact with the molding material. Because it is applied, the molding material does not adhere when manufacturing tablets. As a result, tablets can be manufactured without causing tableting troubles such as stateing, laminating, and caving, thereby improving the tablet manufacturing efficiency. In the method for producing a tablet according to claim 6, the inner peripheral wall surface where the lower punch is inserted to a predetermined position, the lower surface of the upper punch, and the powder material applying method according to claim 1, The powder material is applied to each of the upper surfaces of the lower punches, and the inner surface of the lower punch is uniformly coated with the powder material. The upper punch has a lower surface uniformly coated with the powder materials, and A tablet is manufactured by successively using lower punches having an upper surface on which a powder material is uniformly applied to compress the molding material.
これにより、 粉体材料として、 滑沢剤を用いた場合には、 杵ゃ曰に、 ギシツキ を生じることなく、 且つ、 打錠障害 (ラミネ一ティング、 キヤヅビング、 スティ ッキング等) を生じることなく、 連続打錠が可能になる。 これにより、 生産べ一 スで、 外部滑沢錠剤の製造が可能になる。 As a result, when a lubricant is used as a powder material, Kizuki says that without causing squealing and without tableting troubles (laminating, caving, sticking, etc.) Continuous tableting becomes possible. This makes it possible to manufacture external lubricating tablets on a production basis.
また、 粉 料として、 表面改質剤を用いた場合には、 杵ゃ曰に、 表面改質剤 を均一に塗布できる。 In addition, when a surface modifier is used as the powder, the surface modifier can be uniformly applied by Kizuki.
これにより、 この錠剤の製造方法を用いれば、 表面改質剤が均一に塗布された 杵と臼とを用いて、 錠剤を製造できるので、 錠剤の表面に表面改質剤が均一に塗 布された錠剤を製造できるようになる。 By using this tablet manufacturing method, a tablet can be manufactured using a punch and a die to which the surface modifier has been uniformly applied, so that the surface modifier is uniformly applied to the surface of the tablet. Tablets can be manufactured.
請求項 7に記載の錠剤の製造方法では、 下杵の上面及び下杵が所定の位置まで 挿入された曰の内周壁面への粉体材料の塗布と、 上杵の下面への粉体材料の塗布 とを一連の気流の流れで行うようにし、 下杵の上面及び曰の内周壁面にとって、 余分な粉体材料を、 上杵の下面への塗布に用いているので、 粉体材料を無駄なく、 有効活用できる。 In the tablet manufacturing method according to claim 7, the powder material is applied to the inner peripheral wall surface where the upper surface of the lower punch and the lower punch are inserted to a predetermined position, and the powder material is applied to the lower surface of the upper punch. Is applied in a series of airflows, and excess powder material is used to coat the lower surface of the upper punch for the upper surface of the lower punch and the inner peripheral wall. It can be used effectively without waste.
請求項 8に記載の錠剤の製造方法では、 上杵の下面より上方の位置に吸引口を 有する吸弓 段を設けるという簡単な構成で、 上杵の下面に、 下方から上方に向 かう気流を発生させることができる。 In the tablet manufacturing method according to the eighth aspect, a simple configuration in which a suction step having a suction port is provided at a position above the lower surface of the upper punch, the air flow from the lower side to the upper side is formed on the lower surface of the upper punch. Can be generated.
請求項 9に記載の錠剤の製造方法では、 下杵の上面及び曰の内周壁面に塗布さ れた粉体材料の中、 下杵の上面及び臼の内周壁面にとって余分な粉体材料を、 曰 内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分散した粉体 材料を直接吹き付ける場所とは、 導通しない場所で、 吸引除去するように.してい るので、 曰内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分 散した粉体材料を直接吹き付ける条件に影響を与えることなく、 下杵の上面及び 臼の内周壁面に塗布された粉体材料の中、 下杵の上面及び曰の内周壁面にとって 余分な粉体材料を、 吸引除去することができる。 In the tablet manufacturing method according to claim 9, the tablet is applied to the upper surface of the lower punch and the inner peripheral wall surface. Of the powder material, extra powder material for the upper surface of the lower punch and the inner peripheral wall of the die was dispersed in the air current of the air pulsating wave on the upper surface of the lower punch inserted to a predetermined position. The place where the powder material is directly sprayed is suction-removed in a place where it does not conduct, so it is dispersed into the air current of the air pulsating wave on the upper surface of the lower punch inserted up to the specified position. The powder material applied to the upper surface of the lower punch and the inner peripheral wall of the mortar, without affecting the conditions for directly spraying the powdered material, excess powder for the upper surface of the lower punch and the inner peripheral wall The material can be aspirated off.
請求項 1 0に記載の錠剤の製造方法では、 下杵が、 曰内で最下位となる位置で、 下杵の上面及び曰の内周壁面に、 粉体材料を塗布するようにし、 成形材料を圧縮 成形する際に、 成形材料に接触する曰の内周壁面に、 万遍なく、 粉体材料を塗布 するようにしているので、 曰に、 成形材料が付着しない。 In the method for manufacturing a tablet according to claim 10, the lower punch is applied with a powder material on the upper surface of the lower punch and the inner peripheral wall surface at the lowest position in the mold. During compression molding, the powder material is applied evenly to the inner peripheral wall that comes into contact with the molding material, so that the molding material does not adhere.
請求項 1 1に記載の上杵用の粉体材料の塗布装置では、 上杵の下面に、 空気脈 動波の気流に分散された粉体材料を噴霧する長尺なスリット部を設け、 このスリ ット部の上方を上杵が通過する間に、 時間をかけて、 上杵の下面に、 粉体材料を 噴霧するようにしているので、 重力の関係で、 粉体材料が付着し難い、 上杵の下 面に、 粉体材料を、 ひっつけるようにしているので、 上杵の下面へも、 粉体材料 を均一に塗布できる。 In the powder material applying apparatus for an upper punch according to claim 11, a long slit portion for spraying the powder material dispersed in the air current of the air pulsating wave is provided on a lower surface of the upper punch, The powder material is sprayed on the lower surface of the upper punch over time while the upper punch passes over the slit part, so that the powder material is less likely to adhere due to gravity. Since the powder material is attached to the lower surface of the upper punch, the powder material can be evenly applied to the lower surface of the upper punch.
請求項 1 2に記載の上杵用の粉体材料の塗布装置では、 スリット部の上方には、 スリット部の領域を覆う大きさで、 且つ、 平面視した場合には、 回転テーブルに 設けられた複数の曰の回転軌道の外周側に沿った形状の吸引口を有する第 1の吸 引手段が設けられている。 これにより、 第 1の吸引手段を駆動させると、 スリツ ト部の全領域の上側に、 万遍なく、 下方より上方に向かう気流が発生する。 した がって、 スリット部から吹き出した粉体材料は、 スリット部の全領域から、 万遍 なく、 下方より上方に向かって、 吸引口方向へ移動する。 The powder material application device for an upper punch according to claim 12, wherein the rotary table is provided above the slit in a size large enough to cover the area of the slit, and when viewed in a plan view. A plurality of first suction means having suction ports shaped along the outer peripheral side of the rotating orbit are provided. As a result, when the first suction means is driven, an airflow is generated uniformly above the entire region of the slit portion and directed upward from below. Therefore, the powder material blown out from the slit moves from the entire area of the slit to the suction port direction from above to below.
これにより、 上杵収容溝内を移動してくる、 次の臼に対応して設けられた上杵 の下面には、 上杵が、 長尺なスリット部の起端部から終端部まで移動する間に、 万遍なく、 下方より上方に向かってくる粉体材料が、 下面に概ね垂直方向に衝突 し続けることになる。 As a result, the upper punch moves from the start to the end of the long slit on the lower surface of the upper punch provided for the next die, which moves inside the upper punch receiving groove. In the meantime, the powder material coming upwards from below is evenly colliding with the lower surface in a substantially vertical direction.
このようにして、 粉体材料が、 重力の関係で付着し難い、 上杵の下面へ、 時間 をかけて、 スリット部の全領域から、 万遍なく、 下方より上方に向かって吹き出 す粉体材料を、 ひっつけるようにしているので、 上杵の下面へも、 粉体材料を均 —に塗布できる。 In this way, the powder material is difficult to adhere due to gravity, The powder material that blows out from the lower part to the upper part from the entire area of the slit is evenly attached to the lower part of the upper punch. Can be applied.
また、 空気に混和した粉体材料を、 回転テーブルの回転方向と逆方向に流す構 成にしたので、 空気に混和した粉体材料を、 回転テーブルの回転方向と順方向に 流すようにしているという構成にしたものに比べ、 上杵の下面へ、 粉体材料を効 率良く衝突させることができる。 In addition, since the powder material mixed with air is made to flow in the direction opposite to the rotation direction of the turntable, the powder material mixed with air is made to flow in the forward direction with the rotation direction of the turntable. The powder material can be made to efficiently collide with the lower surface of the upper punch as compared with the configuration described above.
この上杵用の粉体材料の塗布装置では、 このようにして、 効率良く、 上杵の下 面へ、 粉体材料を均一に塗布できる。 In the powder material applying device for the upper punch, the powder material can be efficiently and uniformly applied to the lower surface of the upper punch in this manner.
このため、 この上杵用の粉体材料の塗布装置を用いれば、 その下面に、 万遍な く、 粉体材料が塗布された上杵と、 その上面に、 万遍なく、 粉体材料が塗布され た下杵と、 その内周壁面に、 万遍なく、 粉体材料が塗布された曰とを用いて錠剤 を製造できるので、 粉体材料として、 滑沢剤を用いた場合には、 杵ゃ曰に、 ギシ ツキを生じることなく、 且つ、 打錠障害 (ラミネ一ティング、 キヤッビング、 ス ティヅキング等) を生じることなく、 連続打錠が可能になる。 これにより、 生産 ペースで、 外部滑沢錠剤の製造が可能になる。 For this reason, if the powder material applying device for the upper punch is used, the lower surface is uniformly coated with the powder material, and the upper surface is uniformly coated with the powder material. Tablets can be manufactured using the lower punch that has been applied and the fact that the powder material has been applied evenly on the inner peripheral wall, so if a lubricant is used as the powder material, According to Kizuki, it is possible to perform continuous tableting without causing squeaks and without tableting troubles (laminating, cabbing, sticking, etc.). This allows the production of external lubricating tablets at the production pace.
また、 粉 料として、 表面改質剤を用いた場合には、 杵ゃ曰に、 表面改質剤 を均一に塗布できるので、 この上杵用の粉体材料の塗布装置を用いれば、 表面改 質剤が均一に塗布された杵と曰とを用いて、 錠剤を製造できるので、 錠剤の表面 に表面改質剤が均一に塗布された錠剤を製造できるようになる。 In addition, when a surface modifier is used as a powder, the surface modifier can be uniformly applied to the surface of the punch by using a powder material application device for the upper punch. Since tablets can be manufactured using a punch with a coating agent uniformly applied, it is possible to manufacture tablets in which the surface modifier is uniformly applied to the surface of the tablet.
請求項 1 3に記載の上杵用の粉体材料の塗布装置では、 スリット部の幅を、 錠 剤に形成する割線や刻印の領域の幅に概ね一致するようにしているので、 上杵収 容溝内を移動してくる、 上杵の下面の、 割線や刻印を形成する部分、 即ち、 複雑 な凸部が形成されている部分を中心にして、 上杵の下面に、 粉体材料が塗布され る o In the powder material applying apparatus for an upper punch according to claim 13, the width of the slit portion is made to substantially match the width of the area of the score line or the mark formed on the tablet. The powder material moves on the lower surface of the upper punch, moving around the part forming the score line or marking, that is, the part where the complex protrusion is formed, on the lower surface of the upper punch moving in the groove. Applied o
このように、 この上杵用の粉体材料の塗布装置では、 上杵の下面の、 割線や刻 印を形成する部分に、 十分に且つ均一に、 粉体材料を塗布できるので、 粉体材料 として、 滑沢剤を用いた場合には、 錠剤の、 割線や刻印を設けた部分、 即ち、 複 雑な凹凸が形成されている部分で、 ラミネ一ティング、 キヤヅビング、 ステイツ キングを生じること無く、 錠剤を製造することができる。 As described above, in the powder material applying device for the upper punch, the powder material can be sufficiently and uniformly applied to a portion of the lower surface of the upper punch where a score line or an engraving is formed. In the case where a lubricant is used, the part of the tablet provided with a score line or a mark, that is, a part having a complex unevenness, is used for laminating, caving, and state. Tablets can be produced without kinging.
したがって、 この装置を用いれば、 従来は、 生産ベースで製造することが難し かった、 割線や刻印を設けた外部滑沢錠剤を、 生産ペースで製造することができ るようになる。 Therefore, if this device is used, it will be possible to manufacture external lubricating tablets provided with score lines and stamps at a production pace, which was conventionally difficult to manufacture on a production basis.
また、 この上杵用の粉体材料の塗布装置を用いれば、 従来の粉体材料の塗布装 置では、 粉体材料を塗布するのが困難であった、 上杵の下面の、 割線や刻印を形 成する部分へも、 十分に且つ均一に、 粉体材料を塗布することができるので、 粉 体材料として、 表面改質剤を用いた場合には、 従来、 製造するのが困難であった、 割線や刻印が設けられた部分にも、 均一に、 表面改質剤が塗布された錠剤を製造 することができるようになる。 Also, if the powder material applying device for the upper punch is used, it is difficult to apply the powder material using the conventional powder material applying device. The powder material can be applied sufficiently and evenly to the part that forms the powder, and if a surface modifier is used as the powder material, it has conventionally been difficult to manufacture the powder material. In addition, it becomes possible to manufacture a tablet uniformly coated with a surface modifying agent even at a portion where a score line or a mark is provided.
請求項 1 4に記載の上杵用の粉体材料の塗布装置では、 スリット部の形状を、 ジグザグ形状にしている。 これにより、 上杵収容溝内を移動してくる、 上杵は、 スリット部が、 複数の上杵の回転軌道に沿って、 ただ単に湾曲しているものに比 ぺ、 上杵収容溝内を移動する際に、 より長いスリット部を通過したことになるの で、 尚一層、 上杵の下面に、 十分且つ均一に、 粉体材料が塗布される。 In the powder material applying apparatus for an upper punch according to claim 14, the slit portion has a zigzag shape. As a result, the upper punch, which moves in the upper punch receiving groove, moves in the upper punch receiving groove as compared to the slit whose slit portion is simply curved along the rotation path of the plurality of upper punches. Since the powder material has passed through the longer slit when moving, the powder material is more sufficiently and uniformly applied to the lower surface of the upper punch.
これにより、 粉体材料として、 滑沢剤を用いた場合には、 錠剤の、 割線や刻印 を設けた部分、 即ち、 複雑な凹凸が形成されている部分で、 ラミネーティング、 キヤヅビング、 スティヅキングをより一層生じること無く、 錠剤を製造すること ができる。 したがって、 この装置を用いれば、 割線や刻印を設けた外部滑沢錠剤 を、 より一層高い生産効率で製造することができるようになる。 As a result, when a lubricant is used as the powder material, laminating, caving, and sticking can be performed more in the portion of the tablet where the score lines and markings are provided, that is, in the portion where complex irregularities are formed. Tablets can be produced without any further occurrence. Therefore, if this device is used, an external lubricating tablet provided with a score line and a stamp can be manufactured with higher production efficiency.
また、 この上杵用の粉体材料の塗布装置を用いれば、 上杵の下面の、 割線や刻 印を形成する部分へも、 十分に且つ均一に、 粉 料を塗布することができるの で、 粉体材料として、 表面改質剤を用いた場合には、 割線や刻印が設けられた部 分にも、 均一に、 表面改質剤が塗布された錠剤を、 より一層高い生産効率で製造 することができるようになる。 In addition, if the powder material applying device for the upper punch is used, the powder can be sufficiently and uniformly applied to a portion of the lower surface of the upper punch where a score line or a mark is formed. If a surface modifier is used as the powder material, tablets with the surface modifier applied uniformly at the part where the score line or marking is provided can be manufactured with even higher production efficiency. Will be able to
請求項 1 5に記載の上杵用の粉体材料の塗布装置では、 スリット部の上方に、 所定の孔径を有するメッシュ手段を設けて、 所定粒径以上の粉体材料を、 このメ ッシュ手段でキャッチすることで、 上杵の下面に大粒の粉体材料が付着するのを 阻止できるようにしている。 この結果、 上杵の下面に、 粒径の揃った粉体材料を、 均一に塗布できる。 In the powder material applying apparatus for an upper punch according to claim 15, a mesh means having a predetermined hole diameter is provided above the slit portion, and the powder material having a predetermined particle diameter or more is provided. By catching with, large powder material can be prevented from adhering to the lower surface of the upper punch. As a result, a powder material having a uniform particle size can be uniformly applied to the lower surface of the upper punch.
したがって、 この上杵用の粉体材料の塗布装置を用いれば、 打錠が困難になる ことなく、 且つ、 表面に、 粉体材料を均一に塗布された錠剤を容易に製造できる。 また、 メッシュ手段により、 スリット部から第 1の吸引手段の吸引口へ流れる 気流が整流されるので、 これによつて、 上杵の下面に、 粉体材料が、 一層、 均一 に塗布される。 Therefore, by using the powder material applicator for the upper punch, it is possible to easily produce a tablet on which the powder material is uniformly applied on the surface without making the tableting difficult. Further, since the air flow flowing from the slit portion to the suction port of the first suction means is rectified by the mesh means, the powder material is more uniformly applied to the lower surface of the upper punch.
請求項 1 6に記載の上杵用の粉体材料の塗布装置では、 スリット部の代わりに、 上杵収容溝の底面に、 複数の上杵の回転軌道に沿って、 上杵収容溝内を移動する 複数の上杵の下面に、 空気脈動波の気流に分散された粉体材料を噴霧する、 複数 の噴射孔を配置したので、 粉体材料が、 複数の噴射孔の各々から噴霧される際に、 気流に、 ある種の整流効果が得られる。 In the powder material applying apparatus for an upper punch according to claim 16, instead of the slit portion, the inside of the upper punch receiving groove is formed along the rotation path of the plurality of upper punches on the bottom surface of the upper punch receiving groove. A plurality of injection holes for spraying powder material dispersed in the air current of the air pulsating wave are arranged on the lower surface of the plurality of upper punches that move. The powder material is sprayed from each of the plurality of injection holes. In this case, a certain rectifying effect is obtained in the airflow.
これにより、 重力との関係で、 粉体材料が付着し難い、 上杵の下面に、 粉^ ί 料が、 均一に塗布される。 This makes it difficult for the powder material to adhere due to gravity, and the powder material is uniformly applied to the lower surface of the upper punch.
請求項 1 7に記載の下杵用の粉体材料の塗布装置では、 空気脈動波の気流に分 散された粉体材料を排出口から、 臼内に所定の位置まで挿入された下杵の上面に 吹き付けるようにしているので、 空気脈動波の振幅により、 重力との関係で、 下 杵の上面に余分に、 粉体材料が堆積しても、 空気脈動波により、 そのような余分 な粉体材料が、 下杵の上面から吹き飛ばされる結果、 重力との関係で、 余分な粉 体材料が堆積しがちな下杵の上面に、 粉体材料を均一に塗布できる。 In the powder material applying apparatus for a lower punch according to claim 17, the powder material dispersed in the air current of the air pulsating wave is discharged from an outlet to a lower punch inserted into a die to a predetermined position. Due to the air pulsation wave amplitude, due to the gravitational force due to the amplitude of the air pulsation wave, even if powder material accumulates extra on the upper surface of the lower punch, the air pulsation wave causes such extra powder As a result of the body material being blown off from the upper surface of the lower punch, the powder material can be uniformly applied to the upper surface of the lower punch, where excess powder material tends to accumulate due to gravity.
且つ、 下杵の上面から吹き飛ばされた粉体材料は、 曰の内周壁面に付着するの で、 臼の内周壁面にも、 粉体材料を均一に塗布できる。 In addition, the powder material blown off from the upper surface of the lower punch adheres to the inner peripheral wall surface, so that the powder material can be uniformly applied to the inner peripheral wall surface of the mill.
請求項 1 8に記載の下杵用の粉体材料の塗布装置では、 本体を貫通するように 設けられた貫通孔の排出口より、 曰内に所定の位置まで挿入された下杵の上面に、 空気脈動波に混和された粉体材料を直接吹き付けるようにしている。 これにより、 下杵の上面に、 付着したり、 堆積したりし易い、 余分な粉体材料が、 空気脈動波 により、 下杵の上面から吹き飛ばされる結果、 下杵の上面に、 粉体材料が均一に 塗布される。 In the powder material applying apparatus for a lower punch according to claim 18, the lower punch is inserted to a predetermined position from a discharge hole of a through hole provided so as to penetrate the main body. However, the powder material mixed with the air pulsation wave is directly blown. As a result, excess powder material, which easily adheres or accumulates on the upper surface of the lower punch, is blown off from the upper surface of the lower punch by the air pulsating wave. It is applied evenly.
同様に、 空気脈動波により、 臼の内周壁面に余分に付着している粉体材料も吹 き飛ばされるので、 臼の内周壁面に、 粉体材料が均一に塗布される。 請求項 1 9に記載の下杵用の粉体材料の塗布装置では、 第 2の吸引手段を設け、 下杵及び曰に余分に付着している粉体材料、 及び回転テーブル上の余分な粉 料を除去するようにしている。 、' Similarly, extra powder material adhering to the inner peripheral wall surface of the mortar is also blown off by the air pulsating wave, so that the powder material is uniformly applied to the inner peripheral wall surface of the mortar. The apparatus for applying a powder material for a lower punch according to claim 19, further comprising a second suction means, wherein the lower punch and the powder material adhering extra, and excess powder on the rotary table are provided. The fee is removed. , '
したがって、 例えば、 第 2の吸引手段の下流位置に、 成形材料充填部を設けれ ば、 下杵及び曰により形成される空間内に、 成形材料を充填する工程において、 下杵及び曰に余分に付着している粉体材料、 及び、 回転テーブル上の余分な粉体 材料が、 成形材料中に、 混入することを防ぐことができる。 Therefore, for example, if a molding material filling portion is provided at a position downstream of the second suction means, in the step of filling the molding material into the space formed by the lower punch and the lower punch, the lower punch and the extra It is possible to prevent the adhering powder material and excess powder material on the rotary table from being mixed into the molding material.
これにより、 尚一層、 内部に、 滑沢剤を含むことの無い、 外部滑沢錠剤を、 効 率よく製造することができる。 As a result, an external lubricating tablet that does not contain a lubricant therein can be produced more efficiently.
また、 錠剤内部に、 表面改質剤が混入されていない、 表面改質錠剤の製造が可 能になる。 In addition, it becomes possible to produce a surface-modified tablet in which no surface modifier is mixed in the tablet.
請求項 2 0に記載の下杵用の粉体材料の塗布装置では、 第 2の吸引手段の吸引 口を、 複数の曰の回転軌道に直交するように、 複数の曰の各々及びそれらの周辺 をカバ一できる長さで形成しているので、 下杵及び曰に余分に付着している粉体 材料、 及び回転テーブル上の余分な粉体材料を、 第 2の吸引手段を駆動させるこ とにより効率よく除去することができる。 In the powder material applying apparatus for a lower punch according to claim 20, the suction port of the second suction means is arranged so as to be orthogonal to the plurality of rotation trajectories, and to each of the plurality of rotations and the periphery thereof. The second suction means is driven by the lower punch and the powder material adhering extra to the lower punch and the excess powder material on the rotary table. Can be removed more efficiently.
これにより、 更に、 一層、 内部に、 滑沢剤を含むことの無い、 外部滑沢錠剤を、 効率よく製造することができる。 This makes it possible to efficiently produce an external lubricating tablet that does not further contain a lubricant.
また、 錠剤内部が、 表面改質剤により、 一切、 汚染されていない、 表面改質錠 剤の製造が可能になる。 In addition, it is possible to manufacture surface-modified tablets that are not contaminated at all by the surface modifier inside the tablet.
請求項 2 1に記載の下杵用の粉体材料の塗布装置では、 下杵の上面及び臼の内 周壁面に塗布された粉体材料の中、 下杵の上面及び曰の内周壁面にとつて余分な 粉体材料を、 曰内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流 に分散した粉体材料を直接吹き付ける場所とは、 導通しない場所で、 吸引除去す るようにしているので、 臼内に所定の位置まで挿入された下杵の上面に、 空気脈 動波の気流に分散した粉体材料を直接吹き付ける条件に影響を与えることなく、 下杵の上面及び臼の内周壁面に塗布された粉体材料の中、 下杵の上面及び曰の内 周壁面にとって余分な粉体材料を、 吸引除去することができる。 In the powder material applying apparatus for a lower punch according to claim 21, the powder material applied to the upper surface of the lower punch and the inner peripheral wall of the die, The place where the powder material dispersed in the air current of the air pulsation wave is directly blown onto the upper surface of the lower punch inserted into a predetermined position in the above-mentioned area is sucked and removed. So that the powder material dispersed in the air current of the air pulsating wave is directly sprayed onto the upper surface of the lower punch inserted into the mortar to the specified position, without affecting the condition of the lower punch. Of the powder material applied to the upper surface and the inner peripheral wall surface of the die, the excess powder material for the upper surface of the lower punch and the inner peripheral wall surface can be removed by suction.
請求項 2 2に記載の下杵用の粉体材料の塗布装置では、 滑沢剤を排出する排出 口の前段部に、 成形材料吸引口を有する第 3の吸引手段を設け、 滑沢剤を噴霧す る前に、 曰の内周壁面及び下杵の上面を清浄しているので、 前工程で使用した成 形材料や滑沢剤が、 次工程の錠剤中に混入することがないので、 錠剤を連続的に 製造しても、 錠剤間で、 滑沢剤の使用量等に不均一を生じない。 これにより、 同 じ規格の錠剤を連続的に製造できる。 In the powder material application device for lower punches according to claim 22, the lubricant is discharged. A third suction means having a molding material suction port is provided in the front part of the mouth to clean the inner peripheral wall surface and the upper surface of the lower punch before spraying the lubricant. Since the molding materials and lubricants used do not mix into tablets in the next process, even if tablets are manufactured continuously, the amount of lubricant used among tablets may be uneven. Absent. As a result, tablets of the same standard can be manufactured continuously.
請求項 2 3に記載の粉体材料の塗布装置では、 下杵用の粉体材料の塗布装置に 設けられた貫通孔の排出口より、 曰内に所定の位置まで挿入された下杵の上面に、 空気脈動波に混和された粉体材料を直接吹き付けるようにしている。 これにより、 下杵の上面に、 付着したり、 堆積したりし易い、 余分な粉体材料が、 空気脈動波 により、 下杵の上面から吹き飛ばされる結果、 下杵の上面に、 粉体材料が均一に 塗布される。 In the powder material applying apparatus according to claim 23, the lower punch is inserted to a predetermined position from a discharge hole of a through hole provided in the powder material applying apparatus for the lower punch. Then, the powder material mixed with the air pulsation wave is directly blown. As a result, excess powder material, which easily adheres or accumulates on the upper surface of the lower punch, is blown off from the upper surface of the lower punch by the air pulsating wave. It is applied evenly.
同様に、 空気脈動波により、 曰の内周壁面に余分に付着している粉体材料も吹 き飛ばされるので、 曰の内周壁面に、 粉体材料が均一に塗布される。 Similarly, the powder material adhering extra to the inner peripheral wall is also blown off by the air pulsating wave, so the powder material is uniformly applied to the inner peripheral wall.
更に、 この粉体材料の塗布装置では、 下杵用の粉体材料の塗布装置に上杵用の 粉体材料の塗布装置を回転テーブルの回転方向と逆方向に接続し、 下杵用の粉体 材料の貫通孔の回転テーブルに対向する側の表面側の排出口より、 空気ととも、 下杵用の粉体材料の塗布装置に収容されている、 曰の内周面、 及び、 臼内に所定 の深さまで挿入された下杵の上面に吹き付けられた粉体材料は、 更に、 上杵用の 粉体材料の塗布装置に設けられたスリット部に供給するようにしている。 Further, in this powder material applying device, the powder material applying device for the upper punch is connected to the powder material applying device for the lower punch in a direction opposite to the rotation direction of the rotary table, and the powder for the lower punch is connected. The inner peripheral surface, which is contained in the powder material application device for the lower punch, together with air from the discharge port on the surface side of the through-hole of the body material facing the rotary table. The powder material sprayed on the upper surface of the lower punch inserted into the upper punch to a predetermined depth is further supplied to a slit provided in a powder material application device for the upper punch.
従って、 空気脈動波により、 下杵の上面及び/又は曰の内周壁面より吹き飛ば された余分な粉体材料は、 空気に混和された状態で、 回転テーブルの回転方向と 逆方向 (上流側) に送られ、 スリット部から放出される。 Therefore, the excess powder material blown off from the upper surface of the lower punch and / or the inner peripheral wall surface by the air pulsation wave is mixed with the air, and in a direction opposite to the rotating direction of the rotary table (upstream side). And is released from the slit.
そして、 この粉体材料の塗布装置では、 上杵用の粉体材料の塗布装置には、 長 尺なスリット部の領域を含むように、 回転移動してくる、 複数の上杵を収容する ための、 上杵収容溝を設けているので、 上杵収容溝内を移動してくる、 次の臼に 対応して設けられた上杵の下面には、 上杵が、 長尺なスリット部の起端部から終 端部まで移動する間に、 万遍なく、 下方より上方に向かってくる粉体材料が、 下 面に概ね垂直方向に衝突し続けることになる。 In the powder material coating device, the powder material coating device for the upper punch contains a plurality of upper punches that rotate and move so as to include a long slit region. Because the upper punch receiving groove is provided, the upper punch that moves in the upper punch receiving groove, on the lower surface of the upper punch While moving from the start to the end, the powder material coming from above and below from all over will continue to collide with the lower surface in a substantially vertical direction.
このようにして、 粉体材料が、 重力の関係で付着し難い、 上杵の下面へ、 時間 をかけて、 粉体材料を、 ひっつけるようにしているので、 上杵の下面へも、 粉体 材料を均一に塗布できる。 In this way, the powder material is difficult to adhere due to gravity, So that the powder material is attached to the lower surface of the upper punch so that the powder material can be applied uniformly.
また、 空気に混和した粉体材料を、 回転テーブルの回転方向と逆方向に流す構 成にしたので、 空気に混和した粉体材料を、 回転テーブルの回転方向と順方向に 流すようにしているという構成にしたものに比べ、 上杵の下面へ、 粉体材料を効 率良く衝突させることができる。 これにより、 この粉体材料の塗布装置では、 効 率良く、 上杵の下面へ、 粉体材料を効率良く、 均一に、 塗布できる。 In addition, since the powder material mixed with air is made to flow in the direction opposite to the rotation direction of the turntable, the powder material mixed with air is made to flow in the forward direction with the rotation direction of the turntable. The powder material can be made to efficiently collide with the lower surface of the upper punch as compared with the configuration described above. Thus, the powder material application device can efficiently and uniformly apply the powder material to the lower surface of the upper punch.
従って、 この粉体材料の塗布装置を用いれば、 その下面に、 万遍なく、 粉体材 料が塗布された上杵と、 その上面に、 万遍なく、 粉体材料が塗布された下杵と、 その内周壁面に、 万遍なく、 粉体材料が塗布された曰とを用いて錠剤を製造でき る。 Therefore, if this powder material application device is used, the lower punch, on which the powder material is applied evenly on the lower surface, and the lower punch, on which the powder material is applied evenly on the upper surface, can be used. Tablets can be manufactured using the fact that the powder material is uniformly applied to the inner peripheral wall surface.
これにより、 粉体材料として、 滑沢剤を用いた場合には、 杵ゃ曰に、 ギシヅキ を生じることなく、 且つ、 打錠障害 (ラミネ一ティング、 キヤッビング、 スティ ヅキング等) を生じることなく、 連続打錠が可能になる。 これにより、 生産べ一 スで、 外部滑沢錠剤の製造が可能になる。 As a result, when a lubricant is used as the powder material, Kizuki says, without causing squeaking and without tableting troubles (laminating, cabbing, sticking, etc.) Continuous tableting becomes possible. This makes it possible to manufacture external lubricating tablets on a production basis.
また、 この粉体材料の塗布装置を用いれば、 粉体材料として、 表面改質剤を用 いた場合には、 杵ゃ臼に、 表面改質剤を均一に塗布できるので、 錠剤の表面に表 面改質剤が均一に塗布された錠剤を生産効率良く製造できるようになる。 In addition, if a surface modifier is used as a powder material, the surface modifier can be uniformly applied to a punch and a die by using this powder material coating device. A tablet to which the surface modifier is uniformly applied can be manufactured with high production efficiency.
請求項 2 4に記載の粉体材料の塗布装置では、 この粉体材料の塗布装置を構成 する上杵用の粉体材料の塗布装置のスリット部の上方に、 請求項 1 2に記載の上 杵用の粉体材料の塗布装置と同様の構成を備える第 1の吸引手段を設けているの で、 請求項 1 2に記載の上杵用の粉体材料の塗布装置と同様の効果を奏する。 請求項 2 5に記載の粉体材料の塗布装置では、 この粉体材料の塗布装置を構成 する上杵用の粉体材料の塗布装置のスリット部の幅を、 請求項 1 3に記載の上杵 用の粉体材料の塗布装置と同様、 錠剤に形成する割線や刻印の領域の幅に概ね一 致するようにしているので、 請求項 9に記載の上杵用の粉体材料の塗布装置と同 様の効果を奏する。 In the powder material application device according to claim 24, the powder material application device for the upper punch constituting the powder material application device is provided above the slit portion of the powder material application device. Since the first suction means having the same configuration as that of the powder material applying device for punches is provided, the same effect as the powder material applying device for upper punches according to claim 12 is provided. . In the powder material applying apparatus according to claim 25, the width of the slit portion of the powder material applying apparatus for the upper punch, which constitutes the powder material applying apparatus, is set according to claim 13. 10. The powder material application device for an upper punch according to claim 9, wherein the device is configured to substantially match the width of an area of a score line or a mark formed on a tablet, similarly to the powder material application device for a punch. It has the same effect as.
請求項 2 6に記載の粉体材料の塗布装置では、 この粉体材料の塗布装置を構成 する上杵用の粉体材料の塗布装置のスリット部の形状を、 請求項 1 4に記載の上 杵用の粉体材料の塗布装置と同様、 ジグザグ形状にしているので、 請求項 1 4に 記載の上杵用の粉体材料の塗布装置と同様の効果を奏する。 In the powder material application device according to claim 26, the shape of the slit portion of the powder material application device for the upper punch, which constitutes the powder material application device, is set as described in claim 14. Since it is formed in a zigzag shape as in the powder material application device for punches, the same effect as the powder material application device for upper punches according to claim 14 can be obtained.
請求項 2 7に記載の粉体材料の塗布装置では、 この粉体材料の塗布装置を構成 する上杵用の粉体材料の塗布装置のスリット部の上方に、 請求項 1 5に記載の上 杵用の粉体材料の塗布装置と同様、 所定の孔径を有するメッシュ手段を設けてい るので、 請求項 1 5に記載の上杵用の粉体材料の塗布装置と同様の効果を奏する。 請求項 2 8に記載の粉体材料の塗布装置は、 この粉体材料の塗布装置を構成す る下杵用の粉体材料の塗布装置の排出口を、 請求項 1 8に記載の下杵用の粉体材 料の塗布装置の排出口と同様、 排出口の真下に位置する曰内に所定の位置まで挿 入されている下杵の上面の概ね中心部に、 概ね垂直方向を向くように設けている ので、 請求項 1 8に記載の下杵用の粉体材料の塗布装置と同様の効果を奏する。 請求項 2 9に記載の粉体材料の塗布装置では、 この粉体材料の塗布装置を構成 する下杵用の粉体材料の塗布装置に、 請求項 1 9に記載の下杵用の粉体材料の塗 布装置と同様の構成を有する第 2の吸引手段を更に設けているので、 請求項 1 9 に記載の下杵用の粉体材料の塗布装置と同様の効果を奏する。 In the powder material applying device according to claim 27, the powder material applying device for the upper punch constituting the powder material applying device is provided above the slit portion of the powder material applying device. Since the mesh means having a predetermined hole diameter is provided similarly to the powder material application device for punches, the same effect as the powder material application device for upper punches according to claim 15 can be obtained. The powder material applying device according to claim 28, wherein the discharge port of the powder material applying device for the lower punch constituting the powder material applying device is the lower punch according to claim 18. In the same way as the outlet of the powder material applicator, it is located just below the outlet, and the lower punch is inserted to the specified position in the center of the lower punch. Thus, the same effect as the powder material application device for lower punches according to claim 18 can be obtained. In the powder material application device according to claim 29, the powder material application device for lower punches constituting the powder material application device is the powder material for lower punches according to claim 19. Since the second suction means having the same configuration as that of the material coating device is further provided, the same effect as the powder material coating device for lower punches according to claim 19 can be obtained.
請求項 3 0に記載の粉体材料の塗布装置では、 この粉体材料の塗布装置を構成 する下杵用の粉体材料の塗布装置に設ける第 2の吸引手段の吸引口を、 請求項 2 0に記載の下杵用の粉体材料の塗布装置と同様の構成にしているので、 請求項 2 0に記載の下杵用の粉体材料の塗布装置と同様の効果を奏する。 In the powder material applying apparatus according to claim 30, the suction port of the second suction means provided in the powder material applying apparatus for the lower punch constituting the powder material applying apparatus is provided. Since the configuration is the same as that of the apparatus for applying a powder material for a lower punch described in Item 0, the same effect as that of the apparatus for applying a powder material for a lower punch described in Item 20 is exhibited.
請求項 3 1に記載の粉体材料の塗布装置では、 下杵の上面及び曰の内周壁面に 塗布された粉体材料の中、 下杵の上面及び曰の内周壁面にとって余分な粉体材料 を、 臼内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気流に分散し た粉体材料を直接吹き付ける場所とは、 導通しない場所で、 吸引除去するように しているので、 曰内に所定の位置まで挿入された下杵の上面に、 空気脈動波の気 流に分散した粉体材料を直接吹き付ける条件に影響を与えることなく、 下杵の上 面及び曰の内周壁面に塗布された粉体材料の中、 下杵の上面及び曰の内周壁面に とって余分な粉体材料を、 吸引除去することができる。 In the powder material applying apparatus according to claim 31, in the powder material applied to the upper surface of the lower punch and the inner peripheral wall, excess powder is used for the upper surface of the lower punch and the inner peripheral wall. The material is sucked and removed from the place where the powder material dispersed in the air current of the air pulsating wave is directly blown onto the upper surface of the lower punch inserted into the mortar to the specified position, where it does not conduct. Therefore, without affecting the conditions for directly spraying the powder material dispersed in the air pulsating wave airflow onto the upper surface of the lower punch inserted to a predetermined position, the upper surface of the lower punch and the Of the powder material applied to the inner peripheral wall surface, excess powder material can be removed by suction on the upper surface of the lower punch and the inner peripheral wall surface.
請求項 3 2に記載の粉体材料の塗布装置では、 この粉体材料の塗布装置を構成 する下杵用の粉体材料の塗布装置に、 請求項 2 2に記載の下杵用の粉体材料の塗 布装置と同様の第 3の吸引手段を設けているので、 請求項 2 2に記載の下杵用の 粉体材料の塗布装置と同様の効果を奏する。 In the powder material applying device according to claim 32, the powder material applying device for the lower punch constituting the powder material applying device includes the powder for a lower punch according to claim 22. Material coating Since the third suction means similar to the cloth device is provided, the same effect as the powder material application device for lower punches according to claim 22 can be obtained.
請求項 3 3に記載の粉体材料の塗布装置では、 スリット部の代わりに、 上杵収 容溝の底面に、 複数の上杵の回転軌道に沿って、 上杵収容溝内を移動する複数の 上杵の下面に、 空気脈動波の気流に分散された粉体材料を噴霧する、 複数の噴射 孔を配置したので、 粉体材料が、 複数の噴射孔の各々から噴霧される際に、 気流 に、 ある種の整流効果が得られる。 In the powder material application apparatus according to claim 33, instead of the slit portion, a plurality of the plurality of upper punches that move in the upper punch receiving groove along the rotation path of the plurality of the upper punches on the bottom surface of the upper punch receiving groove. On the lower surface of the upper punch, a plurality of injection holes for spraying the powder material dispersed in the air current of the air pulsating wave are arranged, so when the powder material is sprayed from each of the plurality of injection holes, A certain rectifying effect is obtained in the airflow.
これにより、 重力との関係で、 粉体材料が付着し難い、 上杵の下面に、 粉 料が、 均一に塗布される。 This makes it difficult for the powder material to adhere due to the relationship with gravity, and the powder is uniformly applied to the lower surface of the upper punch.
請求項 3 4に記載の粉体材料の塗布装置では、 この粉体材料の塗布装置を構成 する下杵用の粉体材料の塗布装置に、 回転テーブルの回転方向と順方向の位置に、 上杵用の粉 ^料の塗布装置を接続しているので、 回転テーブルの回転方向と下 杵用の粉体材料の塗布装置から上杵用の粉体材料の塗布装置へと供給される、 空 気に混和した粉体材料の流れの向きが同方向になるので、 少ない抵抗で、 静かな 状態で、 上杵の下面に、 粉体材料を塗布できる。 In the powder material coating apparatus according to claim 34, the powder material coating apparatus for the lower punch, which constitutes the powder material coating apparatus, is provided at a position in the forward direction with respect to the rotation direction of the rotary table. Since the powder coating device for the punch is connected, the rotation direction of the rotary table and the powder material coating device for the lower punch are supplied to the powder material coating device for the upper punch. Since the direction of the flow of the powder material mixed with the air is the same, the powder material can be applied to the lower surface of the upper punch with low resistance and in a quiet state.
請求項 3 5に記載の外部滑沢式打錠機では、 例えば、 従来の口一タリ型打錠機 等打錠機の所定の位置 (滑沢剤噴霧ポイント) に、 請求項 1 1〜3 3のいずれか に記載の粉体材料の塗布装置を固定的に取り付けるという簡単な作業で、 粉体材 料として、 滑沢剤を用いた場合には、 杵ゃ臼に、 ギシツキを生じることなく、 且 つ、 打錠障害 (ラミネ一ティング、 キヤヅビング、 スティヅキング等) を生じる ことなく、 連続打錠が可能になり、 これにより、 生産ベースで、 外部滑沢錠剤の 製造が可能なになる、 外部滑沢式打錠機を市場に提供することができる。 In the external lubricating tableting machine according to claim 35, for example, at a predetermined position (lubricant spraying point) of a conventional tableting machine such as a one-shot tableting machine, In a simple operation of fixedly attaching the powder material application device described in any of 3 above, if a lubricant is used as the powder material, no sticking occurs on the punch and die. In addition, continuous tableting becomes possible without causing tableting troubles (laminating, caving, sticking, etc.), thereby enabling production of external lubricating tablets on a production basis. A lubricating tablet press can be provided on the market.
また、 粉 料として、 表面改質剤を用いた場合には、 杵ゃ臼に、 表面改質剤 を均一に塗布できるので、 この外部滑沢式打錠機を用いれば、 表面改質剤が均一 に塗布された杵と曰とを用いて、 錠剤を製造できるので、 錠剤の表面に表面改質 剤が均一に塗布された錠剤を製造できる、 外部滑沢式打錠機を市場に提供するこ とができる。 In addition, when a surface modifier is used as a powder, the surface modifier can be uniformly applied to a punch and a die. Provide tablets to the market with an external lubricating tablet machine that can manufacture tablets using a uniformly applied punch and that can manufacture tablets with a surface modifier uniformly applied to the tablet surface. be able to.
Claims
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000575683A JP3983476B2 (en) | 1998-10-13 | 1999-10-12 | Powder material coating method, tablet manufacturing method, powder material coating device for upper eyelid, powder material coating device for lower eyelid, powder material coating device, and externally lubricated tablet press |
| AU60068/99A AU6006899A (en) | 1998-10-13 | 1999-10-12 | Method of applying powder material, tablet production method, powder material application device for upper punch, powder material application device for lower punch, powder material application device, and external lubrication compressing machine |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP29082298 | 1998-10-13 | ||
| JP10/290822 | 1998-10-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2000021740A1 true WO2000021740A1 (en) | 2000-04-20 |
Family
ID=17760939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/JP1999/005590 Ceased WO2000021740A1 (en) | 1998-10-13 | 1999-10-12 | Method of applying powder material, tablet production method, powder material application device for upper punch, powder material application device for lower punch, powder material application device, and external lubrication compressing machine |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP3983476B2 (en) |
| AU (1) | AU6006899A (en) |
| WO (1) | WO2000021740A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114247882A (en) * | 2021-11-12 | 2022-03-29 | 宁波新睦科技有限公司 | Powder compression molding equipment for powder metallurgy |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102023116934B4 (en) * | 2023-06-27 | 2025-12-24 | Fette Compacting Gmbh | Rotary press and method for pre-cleaning the press housing of a rotary press |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4373888A (en) * | 1979-07-13 | 1983-02-15 | Takeda Chemical Industries, Ltd. | Apparatus for mass-producing medical tablets |
| JPS59146059U (en) * | 1983-03-17 | 1984-09-29 | 東北金属工業株式会社 | spray nozzle |
| EP0650826A1 (en) * | 1993-11-01 | 1995-05-03 | Kyowa Hakko Kogyo Co., Ltd. | Rotary-type tabletting machine with lubricant spraying means |
| JPH11169437A (en) * | 1997-12-03 | 1999-06-29 | Kyowa Hakko Kogyo Co Ltd | Tablet manufacturing method |
| JP2000005899A (en) * | 1998-06-22 | 2000-01-11 | Kikusui Seisakusho Ltd | Rotary type powder compression molding machine |
-
1999
- 1999-10-12 WO PCT/JP1999/005590 patent/WO2000021740A1/en not_active Ceased
- 1999-10-12 JP JP2000575683A patent/JP3983476B2/en not_active Expired - Lifetime
- 1999-10-12 AU AU60068/99A patent/AU6006899A/en not_active Abandoned
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4373888A (en) * | 1979-07-13 | 1983-02-15 | Takeda Chemical Industries, Ltd. | Apparatus for mass-producing medical tablets |
| JPS59146059U (en) * | 1983-03-17 | 1984-09-29 | 東北金属工業株式会社 | spray nozzle |
| EP0650826A1 (en) * | 1993-11-01 | 1995-05-03 | Kyowa Hakko Kogyo Co., Ltd. | Rotary-type tabletting machine with lubricant spraying means |
| JPH11169437A (en) * | 1997-12-03 | 1999-06-29 | Kyowa Hakko Kogyo Co Ltd | Tablet manufacturing method |
| JP2000005899A (en) * | 1998-06-22 | 2000-01-11 | Kikusui Seisakusho Ltd | Rotary type powder compression molding machine |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114247882A (en) * | 2021-11-12 | 2022-03-29 | 宁波新睦科技有限公司 | Powder compression molding equipment for powder metallurgy |
Also Published As
| Publication number | Publication date |
|---|---|
| AU6006899A (en) | 2000-05-01 |
| JP3983476B2 (en) | 2007-09-26 |
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