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WO2000005369A3 - Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis - Google Patents

Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis Download PDF

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Publication number
WO2000005369A3
WO2000005369A3 PCT/US1999/012839 US9912839W WO0005369A3 WO 2000005369 A3 WO2000005369 A3 WO 2000005369A3 US 9912839 W US9912839 W US 9912839W WO 0005369 A3 WO0005369 A3 WO 0005369A3
Authority
WO
WIPO (PCT)
Prior art keywords
angiogenesis
secreted proteins
amino acid
proteins involved
acid sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/012839
Other languages
French (fr)
Other versions
WO2000005369A2 (en
Inventor
Richard A Shimkets
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CuraGen Corp
Original Assignee
CuraGen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CuraGen Corp filed Critical CuraGen Corp
Priority to JP2000561315A priority Critical patent/JP2002522019A/en
Priority to AU50818/99A priority patent/AU5081899A/en
Priority to CA002335326A priority patent/CA2335326A1/en
Priority to EP99935312A priority patent/EP1098974A2/en
Publication of WO2000005369A2 publication Critical patent/WO2000005369A2/en
Publication of WO2000005369A3 publication Critical patent/WO2000005369A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Novel angiogenesis/anti-angiogenesis secreted proteins and the nucleic acid sequences which encode them are disclosed by the present invention.
PCT/US1999/012839 1998-07-20 1999-07-20 Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis Ceased WO2000005369A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000561315A JP2002522019A (en) 1998-07-20 1999-07-20 Nucleotide and amino acid sequences of secreted proteins involved in angiogenesis
AU50818/99A AU5081899A (en) 1998-07-20 1999-07-20 Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis
CA002335326A CA2335326A1 (en) 1998-07-20 1999-07-20 Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis
EP99935312A EP1098974A2 (en) 1998-07-20 1999-07-20 Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9339798P 1998-07-20 1998-07-20
US60/093,397 1998-07-20
US15068498A 1998-09-10 1998-09-10
US09/150,684 1998-09-10

Publications (2)

Publication Number Publication Date
WO2000005369A2 WO2000005369A2 (en) 2000-02-03
WO2000005369A3 true WO2000005369A3 (en) 2000-06-15

Family

ID=26787485

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/012839 Ceased WO2000005369A2 (en) 1998-07-20 1999-07-20 Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis

Country Status (5)

Country Link
EP (1) EP1098974A2 (en)
JP (1) JP2002522019A (en)
AU (1) AU5081899A (en)
CA (1) CA2335326A1 (en)
WO (1) WO2000005369A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050043234A1 (en) 1996-10-16 2005-02-24 Deisher Theresa A. Novel FGF homologs
US20030224991A1 (en) * 2002-03-11 2003-12-04 Mohanraj Dhanabal Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis
AU2003279835B2 (en) 2002-10-07 2009-09-10 Zymogenetics, Inc. Methods of administering FGF18
JP2012084561A (en) * 2010-10-06 2012-04-26 Fujitsu Semiconductor Ltd Semiconductor device and method of manufacturing the same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998016644A1 (en) * 1996-10-16 1998-04-23 Zymogenetics, Inc. Fibroblast growth factor homologs
WO1999015653A2 (en) * 1997-09-19 1999-04-01 Genentech, Inc. Tie ligand homologues
WO1999040193A1 (en) * 1998-02-04 1999-08-12 Zymogenetics, Inc. Angiopoietin homolog zapo3, dna encoding it, and method of making it

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1132844B (en) 1980-09-15 1986-07-09 Nuovo Pignone Spa IMPROVEMENTS IN THE GRINDING PLIERS FOR TEXTILE FRAMES
EP0123005B1 (en) 1983-04-18 1986-09-17 Maschinenfabrik Sulzer-Rüti Ag Gripper for inserting a weft thread into a gripper weaving machine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998016644A1 (en) * 1996-10-16 1998-04-23 Zymogenetics, Inc. Fibroblast growth factor homologs
WO1999015653A2 (en) * 1997-09-19 1999-04-01 Genentech, Inc. Tie ligand homologues
WO1999040193A1 (en) * 1998-02-04 1999-08-12 Zymogenetics, Inc. Angiopoietin homolog zapo3, dna encoding it, and method of making it

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BECK L JR AND D'AMORE P A: "Vascular development: cellular and molecular regulation", FASEB JOURNAL,US,FED. OF AMERICAN SOC. FOR EXPERIMENTAL BIOLOGY, BETHESDA, MD, vol. 11, no. 11, pages 365-373-373, XP002102631, ISSN: 0892-6638 *
DATABASE EMBL 1 May 1997 (1997-05-01), PRÖLS F. ET AL.: "rat microvascular endotelial differentiation gene 1 (MDG1)", XP002133852 *
DATABASE GENBANK 21 June 1999 (1999-06-21), YE M. ET AL.: "Homo sapiens MDG1", XP002133853 *
DAVIS S ET AL: "Isolation of Angiopoietin-1, a ligand for Tie2 receptor, by secretion-trap expression cloning", CELL,US,CELL PRESS, CAMBRIDGE, NA, vol. 87, no. 87, pages 1161-1169-1167, XP002102730, ISSN: 0092-8674 *
KIM I. ET AL.: "Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin-3", FEBS LETTERS, vol. 443, 29 January 1999 (1999-01-29), pages 353 - 356, XP002126378 *
MAISONPIERRE P C ET AL: "ANGIOPOIETIN-2, A NATURAL ANTAGONIST FOR TIE2 THAT DISRUPTS IN VIVO ANGIOGENESIS", SCIENCE,US,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, vol. 277, pages 55-60, XP002046280, ISSN: 0036-8075 *
OHBAYASHI N. ET AL.: "Structure and function of the mRNA encoding a novel fibroblast growth factor, FGF-18.", J. BIOL. CHEM., vol. 273, no. 29, 17 July 1998 (1998-07-17), pages 18161 - 18164, XP002133851 *
PRÖLS F. ET AL.: "Assignment of themicrovascular endothelial differentiation gene 1 (MDG1) to human chromosome band 14q24.2->q24.3 by fluorescence in situ hybridization.", CYTOGENET. CELL GENET., vol. 79, 1997, pages 149 - 150, XP002133850 *

Also Published As

Publication number Publication date
CA2335326A1 (en) 2000-02-03
JP2002522019A (en) 2002-07-23
AU5081899A (en) 2000-02-14
EP1098974A2 (en) 2001-05-16
WO2000005369A2 (en) 2000-02-03

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