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WO2000071139A3 - Lactobacillus compositions and methods for preventing wound infections and biofilm formation on implantable surgical devices - Google Patents

Lactobacillus compositions and methods for preventing wound infections and biofilm formation on implantable surgical devices Download PDF

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Publication number
WO2000071139A3
WO2000071139A3 PCT/CA2000/000611 CA0000611W WO0071139A3 WO 2000071139 A3 WO2000071139 A3 WO 2000071139A3 CA 0000611 W CA0000611 W CA 0000611W WO 0071139 A3 WO0071139 A3 WO 0071139A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
biofilm formation
surgical devices
wound infections
implantable surgical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CA2000/000611
Other languages
French (fr)
Other versions
WO2000071139A2 (en
Inventor
Gregor Reid
Andrew W Bruce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002374938A priority Critical patent/CA2374938A1/en
Priority to AU49054/00A priority patent/AU4905400A/en
Publication of WO2000071139A2 publication Critical patent/WO2000071139A2/en
Publication of WO2000071139A3 publication Critical patent/WO2000071139A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/733—Fructosans, e.g. inulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

This invention relates to probiotic compositions and their by-products and methods of employing said compositions for inhibiting, treating or preventing wound infections and biofilm formation on implantable surgical devices.
PCT/CA2000/000611 1999-05-25 2000-05-25 Lactobacillus compositions and methods for preventing wound infections and biofilm formation on implantable surgical devices Ceased WO2000071139A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002374938A CA2374938A1 (en) 1999-05-25 2000-05-25 Lactobacillus compositions and methods for preventing wound infections and biofilm formation on implantable surgical devices
AU49054/00A AU4905400A (en) 1999-05-25 2000-05-25 Lactobacillus compositions and methods for preventing wound infections and biofilm formation on implantable surgical devices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13595499P 1999-05-25 1999-05-25
US60/135,954 1999-05-25

Publications (2)

Publication Number Publication Date
WO2000071139A2 WO2000071139A2 (en) 2000-11-30
WO2000071139A3 true WO2000071139A3 (en) 2001-03-08

Family

ID=22470552

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2000/000611 Ceased WO2000071139A2 (en) 1999-05-25 2000-05-25 Lactobacillus compositions and methods for preventing wound infections and biofilm formation on implantable surgical devices

Country Status (3)

Country Link
AU (1) AU4905400A (en)
CA (1) CA2374938A1 (en)
WO (1) WO2000071139A2 (en)

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US7998470B2 (en) 1999-04-30 2011-08-16 Kibow Biotech, Inc. Compositions and methods improving renal function
US6921390B2 (en) 2001-07-23 2005-07-26 Boston Scientific Scimed, Inc. Long-term indwelling medical devices containing slow-releasing antimicrobial agents and having a surfactant surface
FR2828407B1 (en) * 2001-08-10 2005-06-24 Cobiotex COMPOSITIONS BASED ON BACTERIAL COMPLEXES AND THEIR USE FOR THE PREVENTION OF NOSOCOMIAL INFECTIONS
AUPS057102A0 (en) * 2002-02-15 2002-03-07 Vri Biomedical Ltd Compositions and methods for treatment of skin disorders
AU2003245473B2 (en) * 2002-02-15 2007-09-06 Bioxyne Ltd Compositions and methods for treatment of skin disorders
US20050074442A1 (en) 2002-03-13 2005-04-07 Natarajan Ranganathan Compositions and methods for augmenting kidney function
AU2002255717B2 (en) * 2002-03-13 2007-07-26 Kibow Biotech, Inc. Compositions and methods for augmenting kidney function
US9980988B2 (en) 2002-03-13 2018-05-29 Kibow Biotech, Inc. Compositions and methods for augmenting kidney function
US9655932B2 (en) 2002-03-13 2017-05-23 Kibow Biotech, Inc. Composition and method for preventing or treating gout or hyperuricemia
US11103542B2 (en) 2002-03-13 2021-08-31 Kibow Biotech, Inc. Composition and method for maintaining healthy kidney function
WO2005021575A2 (en) * 2003-08-29 2005-03-10 Gregor Reid Bacterial signaling molecules that down-regulate pathogenic bacterial virulence properties
US7332179B2 (en) 2003-12-12 2008-02-19 Kimberly-Clark Worldwide, Inc. Tissue products comprising a cleansing composition
DE102004023612A1 (en) * 2004-05-10 2005-12-01 Helmut Meusel Use of microbial mixed biocoenosis comprising photosynthetic bacteria, actinomycete, lactic acid bacteria, yeast or ferment active fungus, for treating skin inflammations and dermatitis
US7642395B2 (en) 2004-12-28 2010-01-05 Kimberly-Clark Worldwide, Inc. Composition and wipe for reducing viscosity of viscoelastic bodily fluids
EP1736537A1 (en) * 2005-06-22 2006-12-27 OrganoBalance GmbH Methods and means for protecting the skin against pathogenic microorganisms
US10953051B2 (en) 2005-06-22 2021-03-23 Novozymes A/S Methods and means for protecting the skin against pathogenic microorganisms
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
BE1018502A3 (en) * 2009-02-17 2011-02-01 Metatecta Nv PROBIOTIC SOLUTION FOR PROTECTING A SURFACE AND METHOD USING SUCH SOLUTION.
CL2009001506A1 (en) 2009-07-01 2009-09-25 Univ Concepcion Quew
JP5916846B2 (en) * 2011-05-16 2016-05-11 オルガノバランス メディカル アーゲー Novel lactic acid bacteria against bacterial cold and compositions containing them
EP2596776A1 (en) * 2011-11-25 2013-05-29 Micuri ApS A packaged probiotic composition and uses thereof
GB201206599D0 (en) * 2012-04-13 2012-05-30 Univ Manchester Probiotic bacteria
EA201491272A1 (en) * 2012-05-29 2015-10-30 Данута Кружевска NANOPRODUCT, CONTAINING LACTOBACILLUS REUTERI DAN080, SUITABLE FOR PREVENTION AND THERAPY - HUMAN AND VETERINARY AND ITS MEDICAL APPLICATION
EP2674162A1 (en) * 2012-05-29 2013-12-18 Danuta Kruszewska Nanoproduct comprising lactobacillus reuteri dan080 useful in prophylaxis and medicine, both human and veterinary and medical use of the same
RU2015148488A (en) * 2013-04-23 2017-05-25 Терраджен Холдингз Лимитед ANTI-MICROBIAL ACTIVITY BACTERIAL STRAINS AND THEIR COMPOSITIONS FOR BIOCONTROL
CZ201523A3 (en) 2015-01-16 2016-07-27 Bio Agens Research And Development - Bard, S.R.O. Dual microbial preparation for long-term suppression or prevention of symptoms of opportunist microbial infections
WO2017015208A1 (en) * 2015-07-17 2017-01-26 Hollister Incorporated Wound dressing and method for treating acute and chronic wounds
ITUA20164065A1 (en) * 2016-06-01 2017-12-01 Probiotical Spa GEL COMPOSITIONS FOR TOPIC APPLICATIONS BASED ON BACTERIA, PREPARATION OF THE SAME AND THEIR USES.
US11179426B2 (en) 2016-12-29 2021-11-23 Kibow Biotech, Inc. Composition and method for maintaining healthy kidney function
IT201800004036A1 (en) * 2018-03-28 2019-09-28 Teres Srl TRANSDERMAL GEL
CN114767936B (en) * 2022-05-10 2023-04-18 武汉理工大学 Preparation method of composite lactobacillus casei bracket material for repairing skin injury
CN116672512B (en) * 2023-07-18 2025-08-26 山东第一医科大学(山东省医学科学院) An antibacterial biological coating and its preparation method and application

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DE2738652A1 (en) * 1977-08-26 1979-03-15 Seiken Kai Foundational Juridi Lactobacillus preparation for treating inflammatory diseases - obtd. by cultivating Lactobacillus strain in nutrient medium contg. sulphur, nitrogen and carbon cpds.
WO1997014802A1 (en) * 1995-10-20 1997-04-24 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Novel adherence factors of non pathogenic microorganisms and applications thereof for screening microorganisms for specific probiotic properties; novel pharmaceutical compositions and food additives comprising such microorganisms and adherence factors
US5645830A (en) * 1991-11-15 1997-07-08 Research Corporation Technologies, Inc. Lactobacillus and skim milk compositions and methods for preventing microbial urogenital infections
WO1998023727A1 (en) * 1996-11-29 1998-06-04 Bio K + International Inc. Lactic ferment comprising a particular strain of lactobacillus acidophilus and use thereof
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Patent Citations (5)

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DE2738652A1 (en) * 1977-08-26 1979-03-15 Seiken Kai Foundational Juridi Lactobacillus preparation for treating inflammatory diseases - obtd. by cultivating Lactobacillus strain in nutrient medium contg. sulphur, nitrogen and carbon cpds.
US5804179A (en) * 1985-12-31 1998-09-08 Research Corporation Technologies, Inc. Lactobacillus compositions and methods for treating urinary tract infections
US5645830A (en) * 1991-11-15 1997-07-08 Research Corporation Technologies, Inc. Lactobacillus and skim milk compositions and methods for preventing microbial urogenital infections
WO1997014802A1 (en) * 1995-10-20 1997-04-24 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Novel adherence factors of non pathogenic microorganisms and applications thereof for screening microorganisms for specific probiotic properties; novel pharmaceutical compositions and food additives comprising such microorganisms and adherence factors
WO1998023727A1 (en) * 1996-11-29 1998-06-04 Bio K + International Inc. Lactic ferment comprising a particular strain of lactobacillus acidophilus and use thereof

Non-Patent Citations (5)

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HEINEMANN CHRISTINE ET AL: "Purification and characterization of a surface-binding protein from Lactobacillus fermentum RC-14 that inhibits adhesion of Enterococcus faecalis 1131.", FEMS MICROBIOLOGY LETTERS, vol. 190, no. 1, 2000, pages 177 - 180, XP000971010, ISSN: 0378-1097 *
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Publication number Publication date
CA2374938A1 (en) 2000-11-30
WO2000071139A2 (en) 2000-11-30
AU4905400A (en) 2000-12-12

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