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WO2000071191A3 - Cartridge assembly for medicament suspensions - Google Patents

Cartridge assembly for medicament suspensions Download PDF

Info

Publication number
WO2000071191A3
WO2000071191A3 PCT/US2000/011230 US0011230W WO0071191A3 WO 2000071191 A3 WO2000071191 A3 WO 2000071191A3 US 0011230 W US0011230 W US 0011230W WO 0071191 A3 WO0071191 A3 WO 0071191A3
Authority
WO
WIPO (PCT)
Prior art keywords
cartridge
shaped
disk
outlet
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/011230
Other languages
French (fr)
Other versions
WO2000071191A2 (en
Inventor
Michael Rosario Defelippis
Richard Dennis Dimarchi
Bruce Hill Frank
Paul Arthur Hines
Mary Patricia Lents
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Priority to AU44928/00A priority Critical patent/AU4492800A/en
Publication of WO2000071191A2 publication Critical patent/WO2000071191A2/en
Publication of WO2000071191A3 publication Critical patent/WO2000071191A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3255—Containers provided with a piston or a movable bottom, and permitting admixture within the container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/062—Carpules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/25—Mixers with loose mixing elements, e.g. loose balls in a receptacle
    • B01F33/251—Mixers with loose mixing elements, e.g. loose balls in a receptacle using balls as loose mixing element
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A cartridge assembly for use in a pen-type medicament injector. The cartridge assembly comprises a cartridge for receiving a medicament suspension, the cartridge having a needle-pierceable outlet for the liquid medicament at one end thereof. A movable plunger positioned within the cartridge seals the other end. First and second mixing elements are provided within the cartridge to assist in mixing the medicament suspension. A first disk-shaped mixing element is disposed within the cartridge between the plunger and the outlet, the disk-shaped element being sized and shaped to permit its axial movement within the cartridge but to prevent any significant lateral movement. A second bead-shaped mixing element is disposed within the cartridge between the disk-shaped element and the outlet, the bead-shaped element being sized and shaped for free random movement between the disk-shaped element and the outlet.
PCT/US2000/011230 1999-04-30 2000-04-27 Cartridge assembly for medicament suspensions Ceased WO2000071191A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU44928/00A AU4492800A (en) 1999-04-30 2000-04-27 Cartridge assembly for medicament suspensions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30274299A 1999-04-30 1999-04-30
US09/302,742 1999-04-30

Publications (2)

Publication Number Publication Date
WO2000071191A2 WO2000071191A2 (en) 2000-11-30
WO2000071191A3 true WO2000071191A3 (en) 2001-02-08

Family

ID=23169020

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/011230 Ceased WO2000071191A2 (en) 1999-04-30 2000-04-27 Cartridge assembly for medicament suspensions

Country Status (2)

Country Link
AU (1) AU4492800A (en)
WO (1) WO2000071191A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1424984T3 (en) * 2001-08-31 2005-11-14 Novo Nordisk As Liquid insulin cartridge
JP2008539838A (en) * 2005-05-03 2008-11-20 ノボ・ノルデイスク・エー／エス Cartridge containing drug suspension and mixing elements having different densities
WO2009097791A1 (en) * 2008-02-01 2009-08-13 Shaolei Guan Cartridge of pen-type insulin injector

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4850966A (en) * 1986-02-26 1989-07-25 Hoechst Aktiengesellschaft Device for the administration of medicament suspensions
US5578201A (en) * 1993-07-30 1996-11-26 E. I. Du Pont De Nemours And Company Apparatus for mixing liquids used in countercurrent multiphase liquid separation
US5725500A (en) * 1995-06-02 1998-03-10 Eli Lilly And Company Containers for liquid medicaments
WO1998033538A1 (en) * 1997-02-04 1998-08-06 Novo Nordisk A/S A device for the administration of a liquid medicament suspension

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4850966A (en) * 1986-02-26 1989-07-25 Hoechst Aktiengesellschaft Device for the administration of medicament suspensions
US4850966B1 (en) * 1986-02-26 1994-09-06 Hoechst Ag Device for the administration of medicament suspensions
US5578201A (en) * 1993-07-30 1996-11-26 E. I. Du Pont De Nemours And Company Apparatus for mixing liquids used in countercurrent multiphase liquid separation
US5725500A (en) * 1995-06-02 1998-03-10 Eli Lilly And Company Containers for liquid medicaments
WO1998033538A1 (en) * 1997-02-04 1998-08-06 Novo Nordisk A/S A device for the administration of a liquid medicament suspension

Also Published As

Publication number Publication date
AU4492800A (en) 2000-12-12
WO2000071191A2 (en) 2000-11-30

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