WO2000051434A1 - A weak acidic disinfectant - Google Patents
A weak acidic disinfectant Download PDFInfo
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- WO2000051434A1 WO2000051434A1 PCT/CN2000/000032 CN0000032W WO0051434A1 WO 2000051434 A1 WO2000051434 A1 WO 2000051434A1 CN 0000032 W CN0000032 W CN 0000032W WO 0051434 A1 WO0051434 A1 WO 0051434A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
Definitions
- the present invention relates to a disinfectant, and particularly to a weakly acidic disinfectant.
- BACKGROUND OF THE INVENTION Currently, the most widely used disinfectants are hypochlorite, chlorite or chlorine dioxide, which has the advantages of wide sterilization spectrum, low price and convenient use. It is about 8 and is alkaline. Hypochlorite, chlorite or chlorine dioxide dissolves in water under alkaline conditions to generate more hypochlorite ions, 0C plants, and chlorite ions, C10. There is a small amount of hypochlorous acid H0C1 and chlorous acid. The bactericidal effect of hypochlorous acid H0C1 is 80 times that of hypochlorite ion OCr.
- the bactericidal effect of chlorous acid is much greater than that of chlorite. Therefore, in alkaline conditions, in order to achieve effective sterilization effect, it is necessary to Large concentration, generally the effective chlorine concentration is as high as about 1000 ppm. Due to the high concentration, the cost is increased, and it is inevitable that chlorine is released to produce strong irritating and corrosive effects on human skin, soft tissues and mucous membranes. SUMMARY OF THE INVENTION The inventors have conducted long-term research and research on the above-mentioned disadvantages, and created the technical solution of the present invention.
- the purpose of the present invention is to provide a weakly acidic disinfectant, and add a pH adjuster, stabilizer and corrosion inhibitor to hypochlorite, chlorite or chlorine oxide to overcome the disadvantages of the prior art and achieve improvement.
- a weakly acidic disinfectant which is characterized in that the disinfectant includes the following components and a weight ratio of the A component and the B component binary package or the A and B components Mixed unary packaging:
- a agent 2-25 among them, chlorine-containing compound 2-25, surfactant 0-10, stabilizer 0-10, corrosion inhibitor 0-10;
- B agent 2—75 of which, PH adjusting agent 1.5-74, stabilizer 0.5-5 1 5;
- the pH value of the aqueous solution after the A and B agents are dissolved in water is 3-7; the redox potential is 800-l l O Omv; the effective chlorine concentration is 10-500ppm;
- the chlorine-containing compound is selected from at least one of hypochlorite, chlorite, and an oxide of chlorine.
- the chlorine-containing compound is preferably selected from at least one of sodium hypochlorite, calcium hypochlorite, sodium chlorite, calcium chlorite, or chlorine dioxide.
- the surfactant includes commonly used anionic surfactants and / or non-ionic surfactants.
- the pH adjusting agent includes an inorganic acid and / or an organic acid.
- the stabilizer includes sodium chloride, potassium chloride, calcium chloride, sodium sulfate, sodium pyrophosphate, sodium carbonate, sodium bicarbonate, sodium silicate, and dichloroisocyanuric acid or a salt thereof.
- the corrosion inhibitor includes tripolyphosphate, gluconate or phenylphosphonate.
- the tripolyphosphate is preferably sodium tripolyphosphate.
- the gluconate is preferably sodium gluconate.
- the benzoate is preferably sodium benzoate.
- the B agent package device is integrated into the A agent package to form an integrated package or the A agent and the B agent are mixed together and packaged, and the liquid components therein are individually sealed packages.
- the pH of the aqueous solution after the A and B agents are dissolved in water is preferably 4 to 6, and the concentration of available chlorine is preferably 10 to 300 ppm.
- the disinfectant of the present invention adds a pH adjuster to hypochlorite, chlorite or an oxide of chlorine, so that the pH value of the aqueous solution is 3-7.
- a pH adjuster to hypochlorite, chlorite or an oxide of chlorine, so that the pH value of the aqueous solution is 3-7.
- the hypochlorite When chlorite or chlorine oxide is dissolved in water, it produces stable hypochlorous acid H0C 1 and chlorous acid HC 10 2 which greatly improve the bactericidal effect, and the effective chlorine concentration can be reduced to 1 in use. 0-5 00ppm, thereby reducing costs.
- the penetration effect is increased, the disinfection time is shortened, and the efficacy is improved.
- the stability of hypochlorous acid H0C1 and chlorite HC10 2 is increased. Due to the low effective chlorine concentration in the solution during use, it is within In addition, in addition to reducing costs, it also releases very little chlorine, does not cause irritation to the eyeballs, mucous membranes, etc., and reduces harm to users.
- Figure 1 is a test curve of hypochlorous acid concentration as a function of pH.
- the weakly acidic disinfectant of the present invention can be made into a binary packaging dosage form, and the ratio is:
- B agent 1.0 g, of which 0.997 g succinic acid, 0.015 g fruit acid, 0.005 g sodium chloride, 0.01 g sodium sulfate;
- agent B package can be installed in the agent A package to form an integrated package.
- Agent A and agent B can also be mixed together for packaging, but if there is a liquid component, the package must be sealed independently to ensure a longer shelf life.
- the proportion of the weakly acidic disinfectant binary packaging dosage form of the present invention is:
- agent B package can be installed in the agent A package to form an integrated package; agent A and agent B can also be mixed together and packaged.
- the mixing ratio of the weakly acidic disinfectant solid mixed packaging dosage form of the present invention is:
- sodium hypochlorite 1. 21 g, sodium alkyl stele Q. 02 g, succinic acid 2. 14 g, calcium chloride 0.01 g, sodium G. 04 g.
- the method for using it is to dissolve the solid disinfectant in a mixed package in water, which is applied in the same manner as in Example 1, so it will not be repeated.
- composition ratio of the weakly acidic disinfectant solid binary packaging dosage form of the present invention is:
- agent B package can be installed in the agent A package to form an integrated package; agent A and agent B can also be mixed together and packaged.
- the mixing ratio of the weakly acidic disinfectant of the present invention made into a unitary packaging dosage form is:
- agent A 6 grams of agent A, of which 5 grams of sodium chlorite, 0.02 grams of sodium dodecylxanthate, 0.98 grams of sodium carbonate; 10 grams of agent B, of gadolinium oxalate, sodium chloride 0.5 grams, sulfuric acid Sodium 0.8 g, dichloroisocyanuric acid 1.7 g.
- the liquid components are individually sealed and packaged to ensure a longer shelf life.
- the method of using it is the same as that of Example 1, so it will not be repeated.
- the composition ratio of the weakly acidic disinfectant made into the binary packaging dosage form of the present invention is:
- B agent 10 g fruit acid 4 g, sodium sulfate 1 g, and hydrochloric acid 5 g.
- agent B package can be installed into the agent A package to form an integrated package; agent A and agent B can also be mixed and packaged. However, the liquid components are individually sealed and packaged to ensure a longer shelf life.
- the method for using it is the same as that in Embodiment 1, so it will not be repeated.
- composition ratio of the weakly acidic disinfectant made into the binary packaging dosage form of the present invention is:
- agent B package can be installed into the agent A package to form an integrated package; agent A and agent B can also be mixed and packaged. However, the liquid components are individually sealed and packaged to ensure a longer shelf life.
- the method of using it is the same as that of the embodiment 1, so it will not be repeated.
- composition ratio of the weakly acidic disinfectant made into the binary packaging dosage form of the present invention is:
- agent B package can be installed into the agent A package to form an integrated package; agent A and agent B can also be mixed and packaged. However, the liquid components are individually sealed and packaged to ensure a longer shelf life.
- the method for using it is the same as that in Embodiment 1, so it will not be repeated.
- composition ratio of the weakly acidic disinfectant made into the binary packaging dosage form of the present invention is: A dose of 10 grams, of which 4 grams of hypochlorous acid, 0.5 grams, 8 grams of sodium hypochlorite, 0.8 grams of sodium bicarbonate, 0.69 grams of sodium gluconate, 0.01 grams of sodium alkyl benzoate;
- agent B package can be installed into the agent A package to form an integrated package; agent A and agent B can also be mixed and packaged. However, the liquid components are individually sealed and packaged to ensure a longer shelf life.
- the method for using it is the same as that of the embodiment 1, so it will not be repeated.
- composition ratio of the weakly acidic disinfectant made into the binary packaging dosage form of the present invention is:
- B agent 20 grams of B agent, of which 8 grams of oxalic acid, 1.5 grams of citric acid, 1.5 grams of succinic acid, 1 grams of sodium sulfate, 8 grams of dichloroisocyanuric acid.
- agent B package can be installed into the agent A package to form an integrated package; agent A and agent B can also be mixed and packaged. However, the liquid components are individually sealed and packaged to ensure a longer shelf life.
- the method of using it is the same as that of the embodiment 1, so it will not be repeated.
- hypochlorite ocr produces bactericidal effects.
- the bactericidal efficacy of H0C1 is 80 times that of OCl—. It can be seen that after adding an appropriate amount of pH regulator to hypochlorite, the present invention has a redox potential of + 800 ⁇ + 1100mv, making the aqueous solution weakly acidic. It produces stable H0C1 with strong sterilization ability, which greatly increases the sterilization effect.
- the solution When the pH is 1, the solution is strongly acidic, the C1 2 content is above 70%, and the H0C1 content is less than 30%; when the pH is 2, the solution is strongly acidic, the C1 2 content is less than 30%, and the H0C1 content is 70%.
- the pH When the pH is 3, the solution is weakly acidic, the C1 2 content is less than 10%, and the H0C1 content is about 90% or more; when the pH is 4-6, the solution is weakly acidic, the C1 2 content is small, and the H0C1 content About 99%;
- the aqueous solution of chlorite and chlorine dioxide under weakly acidic conditions, has stable chlorite acid with strong bactericidal effect, which has the same effect, so it will not be repeated.
- Real-eyelid method Dissolve sodium hypochlorite in water to prepare an aqueous solution with an effective chlorine concentration of 1000 ppm, and adjust the pH value to test the percentage content of H0C1 and 0C1—
- Test No. 3 when the PH value is 10-8, there is only less than 23% H0C 1 in the solution, and the concentration of 0C 1- is more than 77%.
- the concentration of 0C plant is below 20%.
- the bactericidal effect test of the weakly acidic disinfectant of the present invention is the bactericidal effect test of the weakly acidic disinfectant of the present invention.
- the bactericidal efficacy of the weakly acidic disinfectant of the present invention is tested by the National Center for Disinfection Testing of the Ministry of Health and formulated with various solutions of commonly used alkaline sodium hypochlorite disinfectants, and the time required to kill all the bacteria is measured. The results are shown in the table. 2.
- Test results show that the weakly acidic disinfectant of the present invention has lower efficacy, such as 40 ppm, than the commonly used sodium hypochlorite disinfectant, which has a higher concentration, such as 2000 ppm.
- the weakly acidic disinfectant of the present invention greatly improves the sterilization effect.
- the stability of the weakly acidic disinfectant of the present invention was measured by the National Center for Disinfection Inspection of the Ministry of Health. As a result, the storage period of the binary package was unchanged for two years, and the prepared aqueous solution was unchanged for 20-30 days, indicating that it has good stability. .
- the solubility of chlorine dioxide in water at 4 ° C is 2000cm7 l00ml, which is about 5 times that of chlorine gas. It can be decomposed into HC 10 2 , C 1 2 and 0 2 by heat or light. Its disinfection characteristics in water are shown below several aspects:
- Chlorine dioxide is added to water containing 0.5 to 10 mg / L of ammonia, and it is measured after 2 hours at constant temperature.
- the content of chlorine dioxide is basically unchanged, which proves that chlorine dioxide does not react with ammonia. Therefore, the use of chlorine dioxide as a disinfectant is of great significance in water supply experiments.
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Abstract
Description
弱酸性的消毒剂 发明的技术领域 本发明涉及消毒剂, 特指一种弱酸性的消毒剂。 发明的背景 目前使用最广泛的消毒剂是次氯酸盐、 亚氯酸盐或二氧化氯, 其具有灭菌 谱广、 价格低廉和使用方便等优点, 但常用的上述消毒剂的水溶液 PH值为 8 左右, 呈碱性, 次氯酸盐、 亚氯酸盐或二氧化氯在碱性条件下, 溶于水后生成 较多的次氯酸根离子 0C厂、 亚氯酸根离子 C 10 , 仅有少量的次氯酸 H0C1和亚 氯酸。 而次氯酸 H0C1的杀菌功效是次氯酸根离子 OCr的 80倍, 同样, 亚氯酸 的杀菌功效也远远大于亚氯酸根, 因此在碱性条件下,为达到有效的杀菌功效, 需要加大浓度, 一般有效氯的浓度高达 l OOOppm左右, 由于浓度较高, 增加了 成本, 且不可避免地要释放出氯对人的皮肤、 软组织及粘膜产生较强的剌激和 腐蚀作用。 本发明的概述 本发明人针对上述缺陷进行了长期的研究和 ¾¾r, 创造出本发明的技术方案。 本发明的目的在于提供一种弱酸性的消毒剂, 在次氯酸盐、 亚氯酸盐或氯 的氧化物中加入 PH调节剂、稳定剂和緩蚀剂, 克服现有技术的弊端, 达到提高 杀菌功效、 增加稳定性和降低剌激腐蚀作用的目的。 FIELD OF THE INVENTION The present invention relates to a disinfectant, and particularly to a weakly acidic disinfectant. BACKGROUND OF THE INVENTION Currently, the most widely used disinfectants are hypochlorite, chlorite or chlorine dioxide, which has the advantages of wide sterilization spectrum, low price and convenient use. It is about 8 and is alkaline. Hypochlorite, chlorite or chlorine dioxide dissolves in water under alkaline conditions to generate more hypochlorite ions, 0C plants, and chlorite ions, C10. There is a small amount of hypochlorous acid H0C1 and chlorous acid. The bactericidal effect of hypochlorous acid H0C1 is 80 times that of hypochlorite ion OCr. Similarly, the bactericidal effect of chlorous acid is much greater than that of chlorite. Therefore, in alkaline conditions, in order to achieve effective sterilization effect, it is necessary to Large concentration, generally the effective chlorine concentration is as high as about 1000 ppm. Due to the high concentration, the cost is increased, and it is inevitable that chlorine is released to produce strong irritating and corrosive effects on human skin, soft tissues and mucous membranes. SUMMARY OF THE INVENTION The inventors have conducted long-term research and research on the above-mentioned disadvantages, and created the technical solution of the present invention. The purpose of the present invention is to provide a weakly acidic disinfectant, and add a pH adjuster, stabilizer and corrosion inhibitor to hypochlorite, chlorite or chlorine oxide to overcome the disadvantages of the prior art and achieve improvement. The purpose of bactericidal efficacy, increased stability and reduced irritant corrosion.
本发明的目的是这样实现的: 一种弱酸性的消毒剂, 其特征在于: 该消毒 剂包括下述成份和重量份数配比组成的 A剂和 B剂二元包装或 A剂与 B剂混合 一元包装: The purpose of the present invention is achieved as follows: A weakly acidic disinfectant, which is characterized in that the disinfectant includes the following components and a weight ratio of the A component and the B component binary package or the A and B components Mixed unary packaging:
A剂 2— 25, 其中, 含氯化合物 2— 25 , 表面活性剂 0— 10, 稳定剂 0-10, 緩蚀剂 0-10; B剂 2— 75, 其中, PH调节剂 1. 5— 74 , 稳定剂 0. 5— 1 5 ; A agent 2-25, among them, chlorine-containing compound 2-25, surfactant 0-10, stabilizer 0-10, corrosion inhibitor 0-10; B agent 2—75, of which, PH adjusting agent 1.5-74, stabilizer 0.5-5 1 5;
该 A剂和 B剂溶于水后的水溶液的 PH值为 3— 7 ; 氧化还原电位为 800- l l O Omv; 有效氯浓度为 1 0- 500ppm; The pH value of the aqueous solution after the A and B agents are dissolved in water is 3-7; the redox potential is 800-l l O Omv; the effective chlorine concentration is 10-500ppm;
该含氯化合物选自次氯酸盐、 亚氯酸盐和氯的氧化物中的至少一种。 The chlorine-containing compound is selected from at least one of hypochlorite, chlorite, and an oxide of chlorine.
该含氯化合物优先选自次氯酸钠、 次氯酸钙、 亚氯酸钠、 亚氯酸钙或二氧 化氯中的至少一种。 The chlorine-containing compound is preferably selected from at least one of sodium hypochlorite, calcium hypochlorite, sodium chlorite, calcium chlorite, or chlorine dioxide.
该表面活性剂包括常用的阴离子表面活性剂和 /或非离子表面活性剂。 该 PH调节剂包括无机酸和 /或有机酸。 The surfactant includes commonly used anionic surfactants and / or non-ionic surfactants. The pH adjusting agent includes an inorganic acid and / or an organic acid.
该稳定剂包括氯化钠、 氯化钾、 氯化钙、 硫酸钠、 焦嶙酸钠、 碳酸钠、 碳 酸氢钠、 硅酸钠及二氯异氰尿酸或其盐。 The stabilizer includes sodium chloride, potassium chloride, calcium chloride, sodium sulfate, sodium pyrophosphate, sodium carbonate, sodium bicarbonate, sodium silicate, and dichloroisocyanuric acid or a salt thereof.
该緩蚀剂包括三聚磷酸盐、 葡萄糖酸盐或苯曱酸盐。 The corrosion inhibitor includes tripolyphosphate, gluconate or phenylphosphonate.
该三聚磷酸盐优选为三聚磷酸钠。 The tripolyphosphate is preferably sodium tripolyphosphate.
该葡萄糖酸盐优选为葡萄糖酸钠。 The gluconate is preferably sodium gluconate.
该苯曱酸盐优选为苯曱酸钠。 The benzoate is preferably sodium benzoate.
该 B剂包装置入 A剂包装内形成一体包装或将 A剂和 B剂混合一起包装, 其中的液体组份为独立密封包装。 The B agent package device is integrated into the A agent package to form an integrated package or the A agent and the B agent are mixed together and packaged, and the liquid components therein are individually sealed packages.
该 A剂和 B剂溶于水后的水溶液 PH优选为 4一 6 , 有效氯的浓度优选为 1 0 一 300ppm。 The pH of the aqueous solution after the A and B agents are dissolved in water is preferably 4 to 6, and the concentration of available chlorine is preferably 10 to 300 ppm.
本发明的主要优点是: The main advantages of the invention are:
1、 本发明的消毒剂通过在次氯酸盐、 亚氯酸盐或氯的氧化物中加入 PH调 节剂, 使水溶液的 PH值为 3—7, 在弱酸性条件下, 次氯酸盐、 亚氯酸盐或氯 的氧化物溶于水后, 产生稳定的杀菌功效较高的次氯酸 H0C 1、 亚氯酸 HC 102大 大提高了杀菌功效, 使用中有效氯的浓度可降低到 1 0-5 00ppm之间, 从而降低 成本。 1. The disinfectant of the present invention adds a pH adjuster to hypochlorite, chlorite or an oxide of chlorine, so that the pH value of the aqueous solution is 3-7. Under weak acidic conditions, the hypochlorite, When chlorite or chlorine oxide is dissolved in water, it produces stable hypochlorous acid H0C 1 and chlorous acid HC 10 2 which greatly improve the bactericidal effect, and the effective chlorine concentration can be reduced to 1 in use. 0-5 00ppm, thereby reducing costs.
2、 本发明的消毒剂中, 通过加入表面活性剂, 增加了渗透作用, 缩短了消 毒时间, 提高了功效。 3、 本发明的消毒剂中通过加入无机或有机盐稳定剂, 增加次氯酸 H0C1、 亚氯酸盐 HC102的稳定性,由于使用时溶液中的有效氯浓度较低,在 10— 500ppm 之间, 除降低了成本外, 且极少释放氯, 对眼球、 粘膜等不产生剌激, 减少对 使用者的伤害。 2. In the disinfectant of the present invention, by adding a surfactant, the penetration effect is increased, the disinfection time is shortened, and the efficacy is improved. 3. By adding inorganic or organic salt stabilizers to the disinfectant of the present invention, the stability of hypochlorous acid H0C1 and chlorite HC10 2 is increased. Due to the low effective chlorine concentration in the solution during use, it is within In addition, in addition to reducing costs, it also releases very little chlorine, does not cause irritation to the eyeballs, mucous membranes, etc., and reduces harm to users.
4、 由于加入緩蚀剂, 使消毒液大大减少了对仪器设备和被消毒物的腐蚀性。 本发明的详细描述 下面结合较佳实施例和附图对本发明进一步说明如下: 4. Due to the addition of corrosion inhibitors, the disinfection solution greatly reduces the corrosiveness of the equipment and the disinfected objects. Detailed description of the present invention The present invention is further described below with reference to the preferred embodiments and the accompanying drawings:
图 1为次氯酸浓度随 PH值变化的试验曲线图。 Figure 1 is a test curve of hypochlorous acid concentration as a function of pH.
实施例 1 Example 1
本发明的弱酸性的消毒剂可以做成二元包装剂型, 其配比为: The weakly acidic disinfectant of the present invention can be made into a binary packaging dosage form, and the ratio is:
A剂 0. 6克, 其中次氯酸钠 0. 58克, 十二烷基磺酸钠 0. 02克; A agent 0.6 g, of which sodium hypochlorite 0.58 g, sodium dodecylsulfonate 0.02 g;
B剂 1. 0克, 其中琥珀酸 0. 97克, 果酸 0. 015克, 氯化钠 0. 005克、 硫酸 钠 0. 01克; B agent 1.0 g, of which 0.997 g succinic acid, 0.015 g fruit acid, 0.005 g sodium chloride, 0.01 g sodium sulfate;
可将 B剂包装置入 A剂包装内形成一体包装; 还可以将 A剂和 B剂混合一 起包装, 但是其中若有液体组份, 则必须独立的密封包装, 以保证较长时间的 保质期。 The agent B package can be installed in the agent A package to form an integrated package. Agent A and agent B can also be mixed together for packaging, but if there is a liquid component, the package must be sealed independently to ensure a longer shelf life.
使用时先将 A剂溶解于水中, 再将 B剂溶入搅拌均勾; 对有液体组份的消 毒剂, 使用时, 先将固体组份溶解于水中, 再将密封包装的液体组份溶于水中, 得到 PH值为 3—7的弱酸性消毒溶液。 可根据应用的要求不同, 用水稀释到所 需的浓度,如用于医疗消毒或杀灭病菌,其有效氯的浓度可在 80-500ppm之间, 优选在 80_300ppm之间, 若用于室内或物体表面消毒, 其有效氯的浓度可在 10-80ppm之间。 When using, dissolve agent A in water, and then dissolve agent B in the stirrer. For disinfectants with liquid components, dissolve the solid components in water before use, and then dissolve the liquid components in the sealed package. In water, a weakly acidic disinfection solution with a pH of 3-7 is obtained. It can be diluted with water to the required concentration according to different application requirements. For example, it is used for medical disinfection or killing bacteria. Its effective chlorine concentration can be between 80-500ppm, preferably between 80-300ppm. If it is used indoors or objects Surface disinfection, its effective chlorine concentration can be between 10-80ppm.
实施例 2 Example 2
本发明的弱酸性的消毒剂二元包装剂型的配比为: The proportion of the weakly acidic disinfectant binary packaging dosage form of the present invention is:
A剂 5克, 其中次氯酸钠 4. 5克、 次氯酸钙 0. 35克、 十二烷基^ ^酸钠 0. 15 克; A agent 5 g, of which sodium hypochlorite 4.5 g, calcium hypochlorite 0.35 g, dodecyl ^ sodium 0.15 Grams
B剂 7克, 其中柠檬酸 6克、 氯化钾 0. 5克、 硫酸钠 0. 5克。 B agent 7 grams, of which 6 grams of citric acid, 0.5 grams of potassium chloride, 0.5 grams of sodium sulfate.
可将 B剂包装置入 A剂包装内形成一体包装; 还可以将 A剂和 B剂混合一 起包装。 The agent B package can be installed in the agent A package to form an integrated package; agent A and agent B can also be mixed together and packaged.
其使用方法同实施例 1 , 故不重述。 The method of using it is the same as that of Embodiment 1, so it will not be repeated.
实施例 3 Example 3
本发明的弱酸性的消毒剂固体混合包装剂型的配比为: The mixing ratio of the weakly acidic disinfectant solid mixed packaging dosage form of the present invention is:
其中次氯酸钠 1. 21克、烷基碑酸钠 Q. 02克、琥珀酸 2. 14克、氯化钙 0. 01 克、 酸钠 G. 04克。 Among them, sodium hypochlorite 1. 21 g, sodium alkyl stele Q. 02 g, succinic acid 2. 14 g, calcium chloride 0.01 g, sodium G. 04 g.
其使用方法为将混合包装的固体消毒剂溶于水中, 同实施例 1 的方法应 用, 故不重述。 The method for using it is to dissolve the solid disinfectant in a mixed package in water, which is applied in the same manner as in Example 1, so it will not be repeated.
实施例 4 Example 4
本发明的弱酸性的消毒剂固体二元包装剂型的配比为: The composition ratio of the weakly acidic disinfectant solid binary packaging dosage form of the present invention is:
A剂 2. 64克, 其中次氯酸钠 2. 62克, 硬脂酸乙二醇脂活性剂 0. 02克; B剂 4. 36克, 其中苹果酸 4. 30克、 氯化钾 0. 02克、 硫酸钠 0. 04克。 可将 B剂包装置入 A剂包装内形成一体包装; 还可以将 A剂和 B剂混合一 起包装。 02 克。 A agent 2.64 grams, of which sodium hypochlorite 2.62 grams, glycol stearate lipid active agent 0.02 grams; B agent 4. 36 grams, of which malic acid 4. 30 grams, potassium chloride 0.02 grams 04. Sodium sulfate. The agent B package can be installed in the agent A package to form an integrated package; agent A and agent B can also be mixed together and packaged.
其使用方法同实施例 1, 故不重述。 The method of using it is the same as that of Embodiment 1, so it will not be repeated.
实施例 5 Example 5
本发明的弱酸性的消毒剂做成混合一元包装剂型的配比为: The mixing ratio of the weakly acidic disinfectant of the present invention made into a unitary packaging dosage form is:
A剂 6克, 其中亚氯酸钠 5克, 十二 ^黄酸钠 0. 02克、 碳酸钠 0. 98克; B剂 10克, 其中草酸 Ί克、 氯化钠 0. 5克、 硫酸钠 0. 8克、 二氯异氰尿酸 1. 7克。 6 grams of agent A, of which 5 grams of sodium chlorite, 0.02 grams of sodium dodecylxanthate, 0.98 grams of sodium carbonate; 10 grams of agent B, of gadolinium oxalate, sodium chloride 0.5 grams, sulfuric acid Sodium 0.8 g, dichloroisocyanuric acid 1.7 g.
但是其中的液体组份为独立的密封包装, 以保证较长时间的保质期。 其使 用方法同实施例 1 , 故不重述。 本发明的弱酸性的消毒剂做成二元包装剂型的配比为: However, the liquid components are individually sealed and packaged to ensure a longer shelf life. The method of using it is the same as that of Example 1, so it will not be repeated. The composition ratio of the weakly acidic disinfectant made into the binary packaging dosage form of the present invention is:
A剂 7克,其中二氧化氯 6. 45克、十二烷基苯碌酸钠 0. 01克、碳酸钠 0. 02 克、 三聚碑酸钠 0. 02克、 葡萄糖酸钠 0. 5克。 A agent 7 grams, including 6.45 grams of chlorine dioxide, 0.01 grams of sodium dodecylbenzoate, 0.02 grams of sodium carbonate, 0.02 grams of sodium trimerate, 0.2 grams of sodium gluconate 0.5 G.
B剂 10克, 果酸 4克、 硫酸钠 1克、 盐酸 5克。 B agent 10 g, fruit acid 4 g, sodium sulfate 1 g, and hydrochloric acid 5 g.
可将 B剂包装置入 A剂包装内形成一体包装; 还可以将 A剂和 B剂混合包 装。 但是其中的液体组份为独立的密封包装, 以保证较长时间的保质期。 其使 用方法同实施例 1 , 故不重述。 The agent B package can be installed into the agent A package to form an integrated package; agent A and agent B can also be mixed and packaged. However, the liquid components are individually sealed and packaged to ensure a longer shelf life. The method for using it is the same as that in Embodiment 1, so it will not be repeated.
实施例 7 Example 7
本发明的弱酸性的消毒剂做成二元包装剂型的配比为: The composition ratio of the weakly acidic disinfectant made into the binary packaging dosage form of the present invention is:
A剂 8克, 其中次氯酸钙 7. 3克, 碳酸钠 0. 02克、 碳酸氢钠 0. 07克、 葡 萄糖酸钠 0. 6克、 苯曱酸钠 0. 01克; A agent 8 grams, of which 7.3 grams of calcium hypochlorite, 0.02 grams of sodium carbonate, 0.07 grams of sodium bicarbonate, 0.6 grams of sodium gluconate, 0.01 grams of sodium benzoate
B剂 10克, 其中草酸 4克、 柠檬酸 1克、 琥珀酸 3克、 氯化钾 0. 01克、 硫酸钠 G. 02克、 二氯异氰尿酸钠 1. 97克。 B agent 10 grams, of which 4 grams of oxalic acid, 1 grams of citric acid, 3 grams of succinic acid, 0.01 grams of potassium chloride, sodium sulfate G. 02 grams, 1.97 grams of sodium dichloroisocyanurate.
可将 B剂包装置入 A剂包装内形成一体包装; 还可以将 A剂和 B剂混合包 装。 但是其中的液体组份为独立的密封包装, 以保证较长时间的保质期。 其使 用方法同实施例 1, 故不重述。 The agent B package can be installed into the agent A package to form an integrated package; agent A and agent B can also be mixed and packaged. However, the liquid components are individually sealed and packaged to ensure a longer shelf life. The method of using it is the same as that of the embodiment 1, so it will not be repeated.
实施例 8 Example 8
本发明的弱酸性的消毒剂做成二元包装剂型的配比为: The composition ratio of the weakly acidic disinfectant made into the binary packaging dosage form of the present invention is:
A剂 9克, 其中次氯酸钙 4克, 亚氯酸钠 4克、 硅酸钠 0. 4克、 碳酸氢钠 0. 1克、 三聚磷酸钠 0. 5克; A agent 9 grams, of which 4 grams of calcium hypochlorite, 4 grams of sodium chlorite, 0.4 grams of sodium silicate, 0.1 grams of sodium bicarbonate, 0.5 grams of sodium tripolyphosphate;
B剂 10克, 其中草酸 3. 5克、 柠檬酸 4克、 二氯异氰尿酸 2. 5克。 B agent 10 grams, of which 3.5 grams of oxalic acid, 4 grams of citric acid, 2.5 grams of dichloroisocyanuric acid.
可将 B剂包装置入 A剂包装内形成一体包装; 还可以将 A剂和 B剂混合包 装。 但是其中的液体组份为独立的密封包装, 以保证较长时间的保质期。 其使 用方法同实施例 1 , 故不重述。 The agent B package can be installed into the agent A package to form an integrated package; agent A and agent B can also be mixed and packaged. However, the liquid components are individually sealed and packaged to ensure a longer shelf life. The method for using it is the same as that in Embodiment 1, so it will not be repeated.
实施例 9 Example 9
本发明的弱酸性的消毒剂做成二元包装剂型的配比为: A剂 10克, 其中次氯酸 4丐 0.5克, 次氯酸钠 8克、 碳酸氢钠 0.8克、 葡萄 糖酸钠 0.69克、 烷基碑酸钠 0.01克; The composition ratio of the weakly acidic disinfectant made into the binary packaging dosage form of the present invention is: A dose of 10 grams, of which 4 grams of hypochlorous acid, 0.5 grams, 8 grams of sodium hypochlorite, 0.8 grams of sodium bicarbonate, 0.69 grams of sodium gluconate, 0.01 grams of sodium alkyl benzoate;
B剂 10克, 其中盐酸 5克、 果酸 2克、 琥珀酸 2.95克、 氯化钠 0.02克、 硫酸钠 Q. G3克。 B agent 10 grams, of which 5 grams of hydrochloric acid, 2 grams of fruit acid, 2.95 grams of succinic acid, 0.02 grams of sodium chloride, sodium sulfate Q. G3 grams.
可将 B剂包装置入 A剂包装内形成一体包装; 还可以将 A剂和 B剂混合包 装。 但是其中的液体组份为独立的密封包装, 以保证较长时间的保质期。 其使 用方法同实施例 1, 故不重述。 The agent B package can be installed into the agent A package to form an integrated package; agent A and agent B can also be mixed and packaged. However, the liquid components are individually sealed and packaged to ensure a longer shelf life. The method for using it is the same as that of the embodiment 1, so it will not be repeated.
实施例 10 Example 10
本发明的弱酸性的消毒剂做成二元包装剂型的配比为: The composition ratio of the weakly acidic disinfectant made into the binary packaging dosage form of the present invention is:
A剂 10克, 其中次氯酸钙 8克, 碳酸钠 0.15克、 葡萄糖酸钠 0.85克、 次 氯酸钠 1克; A dose of 10 grams, of which 8 grams of calcium hypochlorite, 0.15 grams of sodium carbonate, 0.85 grams of sodium gluconate, 1 grams of sodium hypochlorite;
B剂 20克, 其中草酸 8克、 柠檬酸 1.5克、 琥珀酸 1.5克、 硫酸钠 1克、 二氯异氰尿酸 8克。 20 grams of B agent, of which 8 grams of oxalic acid, 1.5 grams of citric acid, 1.5 grams of succinic acid, 1 grams of sodium sulfate, 8 grams of dichloroisocyanuric acid.
可将 B剂包装置入 A剂包装内形成一体包装; 还可以将 A剂和 B剂混合包 装。 但是其中的液体组份为独立的密封包装, 以保证较长时间的保质期。 其使 用方法同实施例 1, 故不重述。 The agent B package can be installed into the agent A package to form an integrated package; agent A and agent B can also be mixed and packaged. However, the liquid components are individually sealed and packaged to ensure a longer shelf life. The method of using it is the same as that of the embodiment 1, so it will not be repeated.
实施例 11 Example 11
参阅图 1, 次氯酸盐在不同 PH条件下的浓度变化试验。 Refer to Figure 1, the concentration change test of hypochlorite under different pH conditions.
以次氯酸钠为例, 将次氯酸钠溶于水中, PH值约为 8, 其立刻水解出 -OCr 、 H\ Na+ , 水解方程式为: Take sodium hypochlorite as an example. Sodium hypochlorite is dissolved in water with a pH value of about 8. It immediately hydrolyzes out -OCr, H \ Na +, and the hydrolysis equation is:
NaOCl + H20→Na+ +0CT + HO— + 2H + NaOCl + H 2 0 → Na + + 0CT + HO— + 2H +
其中的次氯酸根 ocr产生杀菌功效。 Hypochlorite ocr produces bactericidal effects.
而当加入酸调 PH值为 3— 7时, 次氯酸钠溶于酸性的水溶液中, 则会产生 稳定的 H0C1和 Na+, 水解方程式为: When the pH value is adjusted to 3-7 by adding acid, sodium hypochlorite is dissolved in the acidic aqueous solution, and stable H0C1 and Na + will be generated. The hydrolysis equation is:
H + H +
NaOCl + H20 ^Na+ + H0C1 + H0" + H + 经测试, H0C1的杀菌功效为 OCl—的 80倍, 由此可见, 本发明在次氯酸盐中加 入适量的 PH调节剂后,其氧化还原电位为 +800~+1100mv,使水溶液呈弱酸性, 产生稳定的具较强杀菌能力的 H0C1, 极大地增加了杀菌功效。 NaOCl + H 2 0 ^ Na + + H0C1 + H0 "+ H + After testing, the bactericidal efficacy of H0C1 is 80 times that of OCl—. It can be seen that after adding an appropriate amount of pH regulator to hypochlorite, the present invention has a redox potential of + 800 ~ + 1100mv, making the aqueous solution weakly acidic. It produces stable H0C1 with strong sterilization ability, which greatly increases the sterilization effect.
当继续增加水溶液中酸的浓度呈强酸性, 即 PH值为 3以下时,通过氧化电 位测知, 其 H0C1的浓度下降, 证明: H0C1在强酸性条件不稳定。 因此实验证 明在弱酸条件下 PH3— 7, 最好是 PH4— 6, 次氯酸盐具有最强的杀菌功效。 When the acid concentration in the aqueous solution is continuously increased to show a strong acidity, that is, when the pH value is less than 3, the H0C1 concentration decreases by the oxidation potential measurement, which proves that: H0C1 is unstable under strong acidic conditions. Therefore, it is verified that under weak acid conditions, PH3-7, preferably PH4-6, hypochlorite has the strongest bactericidal effect.
下述实验可进一步证明上述试验结果, 方法是将 C12溶解于水中, 其水解 方程式为 C12+H20— HC1+H0C1逐渐加入减使 PH值逐渐增加, 测定不同 PH值下 溶液中 Cl2、 HOCK 和 0C1—的浓度, 结果见图 1所示: The following experiment can further prove the above test results. The method is to dissolve C1 2 in water, and its hydrolysis equation is C1 2 + H 2 0— HC1 + H0C1. Gradually add and subtract to gradually increase the pH value, and measure the Cl in the solution at different pH values. 2. The concentrations of HOCK and 0C1—, the results are shown in Figure 1:
当 PH为 1时, 溶液为强酸性, C12含量在 70%以上, H0C1含量在 30%以下; 当 PH为 2时, 溶液为强酸性, C12含量在 30%以下, H0C1含量在 70%左右; 当 PH为 3时, 溶液为弱酸性, C12含量在 10%以下, H0C1含量约为 90%以上; 当 PH为 4-6时, 溶液为弱酸性, C12量很少, H0C1含量约为 99%; When the pH is 1, the solution is strongly acidic, the C1 2 content is above 70%, and the H0C1 content is less than 30%; when the pH is 2, the solution is strongly acidic, the C1 2 content is less than 30%, and the H0C1 content is 70%. When the pH is 3, the solution is weakly acidic, the C1 2 content is less than 10%, and the H0C1 content is about 90% or more; when the pH is 4-6, the solution is weakly acidic, the C1 2 content is small, and the H0C1 content About 99%;
当 PH为 7时, 溶液为中性, OCr含量在 20%左右, H0C1含量在 80%以上; 当 PH为 8时, 溶液为碱性, OCr含量在 80%以上, H0C1含量在 20%以下; 从上述试验证明: 当 PH为 3— 7时, Η0Π的含量稳定在 80%以上; 特别是当 PH为 4一 6时, H0C1的含量几乎稳定在 99%左右。 When the pH is 7, the solution is neutral, the OCr content is about 20%, and the H0C1 content is more than 80%; when the pH is 8, the solution is alkaline, the OCr content is more than 80%, and the H0C1 content is less than 20%; From the above test, it is proved that: when the pH is 3-7, the content of Η0Π is stable above 80%; especially when the pH is 4-6, the content of H0C1 is almost stable at about 99%.
上述试验结果进一步证明: 调整溶液为弱酸性时, 即 PH值为 3— 7时, 具 有较强杀菌功效的 H0C1稳定存在。 The above test results further prove that when the adjusting solution is weakly acidic, that is, when the pH value is 3-7, H0C1, which has strong bactericidal effect, exists stably.
同理, 亚氯酸盐和二氧化氯的水溶液, 在弱酸性条件下, 稳定存在具有较 强杀菌功效的亚氯酸, 具有相同的功效, 故不重述。 Similarly, the aqueous solution of chlorite and chlorine dioxide, under weakly acidic conditions, has stable chlorite acid with strong bactericidal effect, which has the same effect, so it will not be repeated.
实施例 12 Example 12
次氯酸盐在不同 PH条件下的 H0C1和 OCr的含量试验。 Test of H0C1 and OCr content of hypochlorite under different pH conditions.
实-睑方法: 将次氯酸钠溶于水中配成含有效氯浓度为 lOOOppm的水溶液, 调 PH值分别测试 H0C1和 0C1—的百分含量: Real-eyelid method: Dissolve sodium hypochlorite in water to prepare an aqueous solution with an effective chlorine concentration of 1000 ppm, and adjust the pH value to test the percentage content of H0C1 and 0C1—
结果见表 1: 表 1 次氯酸钠在不同 PH值下的 H0C 1和 0C 1—含量 The results are shown in Table 1: Table 1 H0C 1 and 0C 1 content of sodium hypochlorite at different pH values
从试验结杲表明: Results from the tests indicate that:
1、 试验号卜 3, PH值为 10- 8时, 溶液中只有 23%以下的 H0C 1 , 而 0C 1—的 浓度在 77%以上。 1. Test No. 3, when the PH value is 10-8, there is only less than 23% H0C 1 in the solution, and the concentration of 0C 1- is more than 77%.
2、 试验号 4— 9 , PH为 7. 0—3. 5时, 溶液中 H0C 1的浓度在 80%以上, 而 2. Test No. 4-9, pH 7.0-3.5, the concentration of H0C 1 in the solution is above 80%, and
0C厂的浓度在 20%以下。 The concentration of 0C plant is below 20%.
证明在弱酸性条件下, 溶液中稳定存在 80%以上的具较强杀菌功效的 H0CL Prove that more than 80% H0CL with strong bactericidal effect is stably present in the solution under weak acidic conditions
实施例 13 Example 13
本发明的弱酸性的消毒剂的杀菌效杲试验。 The bactericidal effect test of the weakly acidic disinfectant of the present invention.
本发明的弱酸性消毒剂的杀菌功效, 经国家卫生部消毒检测中心检测并与 常用碱性次氯酸钠消毒剂分别配成多种浓度的溶液, 分别测量其全部杀灭病菌 所需时间, 结果见表 2。 The bactericidal efficacy of the weakly acidic disinfectant of the present invention is tested by the National Center for Disinfection Testing of the Ministry of Health and formulated with various solutions of commonly used alkaline sodium hypochlorite disinfectants, and the time required to kill all the bacteria is measured. The results are shown in the table. 2.
表 2 消毒剂完全杀灭病菌所需时间 ( Table 2 Time required for disinfectant to completely kill the germs (
有效氦 大肠 乙肝病毒表面 枯草杆菌黑色变种芽胞 消毒刑名 ; H1® 对 Effective helium colibacillus virus surface bacillus subtilis black variant spore disinfection; H 1 ® pair
金黄色葡萄球 Golden yellow grape ball
PH值 浓度 ppm 8099 坑原的破坏作用 ATCC9372 PH value Concentration ppm 8099 Destructive effects of pits ATCC9372
称 ATCC6578 Call ATCC6578
200 ― ― ― 常用次氣 8-10 1000 20-30 60 60-120 20-30 酸钠 2000 10-20 40 40-60 15-25 200 ― ― ― Commonly used secondary gas 8-10 1000 20-30 60 60-120 20-30 Sodium 2000 10-20 40 40-60 15-25
40 20 20 60-120 20 本发明的 40 20 20 60-120 20 of the present invention
4-6.8 80 10 15 20 10 ' 1 200 10 10 10 10 4-6.8 80 10 15 20 10 '1 200 10 10 10 10
300 5 5 10 5 注: 其中 "一" 表示不能完全杀灭病菌。 300 5 5 10 5 Note: "One" means that the bacteria cannot be completely killed.
从试验结杲表明, 本发明的弱酸性消毒剂在较低浓度时, 如 40ppm,具有优 于常用次氯酸钠消毒剂较高浓度如 2000ppm的功效。 Test results show that the weakly acidic disinfectant of the present invention has lower efficacy, such as 40 ppm, than the commonly used sodium hypochlorite disinfectant, which has a higher concentration, such as 2000 ppm.
证明本发明的弱酸性的消毒剂 , 大大提高了杀菌功效。 It is proved that the weakly acidic disinfectant of the present invention greatly improves the sterilization effect.
实施例 14 Example 14
本发明的弱酸性消毒剂的稳定性试验。 Stability test of the weakly acidic disinfectant of the present invention.
本发明的弱酸性消毒剂的稳定性经国家卫生部消毒检验中心测定, 结果为 二元包装贮存期为二年无变化,配制的水溶液为 20— 30日无变化,说明具有较 好的稳定性。 The stability of the weakly acidic disinfectant of the present invention was measured by the National Center for Disinfection Inspection of the Ministry of Health. As a result, the storage period of the binary package was unchanged for two years, and the prepared aqueous solution was unchanged for 20-30 days, indicating that it has good stability. .
实施例 1 5 Example 1 5
关于本发明的二氧化氯的杀菌功效试验研究。 Experimental study on the bactericidal efficacy of the chlorine dioxide of the present invention.
二氧化氯在 4 °C水中的溶解度为 2000cm7 l 00ml, 约为氯气的 5倍, 其遇热 或光可分解成 HC 102、 C 12和 02, 其在水中的消毒特点表现在下述几个方面:The solubility of chlorine dioxide in water at 4 ° C is 2000cm7 l00ml, which is about 5 times that of chlorine gas. It can be decomposed into HC 10 2 , C 1 2 and 0 2 by heat or light. Its disinfection characteristics in water are shown below several aspects:
1、 能杀灭水中的病原菌和病毒。 1. Can kill pathogens and viruses in water.
2、 脱色去味的效果较好, 特别对除酚臭的作用更佳。 2. The effect of decolorization and deodorization is better, especially the effect of removing phenolic odor is better.
3、 沉淀铁和锰的效果较佳。 3. The effect of precipitation of iron and manganese is better.
4、 可减少水中三氯甲烷等有害物质的形成。 4, can reduce the formation of harmful substances such as chloroform in water.
5、 特别是对水中含氨时, 不降低氯化和消毒作用, 此特点可用下述试验 证明: 将二氧化氯加入含氨 0. 5- 10mg/L的水中, 恒温放置 2小时后, 测定二氧 化氯的含量基本不变化, 证明二氧化氯与氨不发生反应。 所以用二氧化氯作消 毒剂在给水实验中具有重大意义。 5. Especially when ammonia is contained in the water, it does not reduce the chlorination and disinfection effects. This feature can be proved by the following tests: Chlorine dioxide is added to water containing 0.5 to 10 mg / L of ammonia, and it is measured after 2 hours at constant temperature. The content of chlorine dioxide is basically unchanged, which proves that chlorine dioxide does not react with ammonia. Therefore, the use of chlorine dioxide as a disinfectant is of great significance in water supply experiments.
Claims
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| PCT/CN2000/000032 Ceased WO2000051434A1 (en) | 1999-02-26 | 2000-02-21 | A weak acidic disinfectant |
Country Status (3)
| Country | Link |
|---|---|
| CN (2) | CN1264539A (en) |
| AU (1) | AU2792400A (en) |
| WO (1) | WO2000051434A1 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1969938A3 (en) * | 2007-03-16 | 2010-03-10 | Bou-Matic Technologies Corporation | Stabilized chlorine dioxide and hypochlorous acid in a liquid biocide |
| EP2106699A1 (en) * | 2008-04-05 | 2009-10-07 | Cealin Chemische Fabrik GmbH | Aqueous solution for oxidation, disinfection and deodorising and method for producing this solution |
| EP2277827A2 (en) * | 2008-04-11 | 2011-01-26 | Aquilabs S.A. | Method of producing composition of hypochlorous acid and use thereof |
| US8945630B2 (en) * | 2008-04-11 | 2015-02-03 | Aquilabs S.A. | Method of producing and applications of composition of hypochlorous acid |
| GB2477597B (en) * | 2010-02-03 | 2012-01-11 | Mauve Technology Ltd | Disinfectant materials and methods |
| GB2477717A (en) * | 2010-02-03 | 2011-08-17 | Mauve Technology Ltd | Disinfectant materials and methods |
| US8883222B2 (en) | 2010-02-03 | 2014-11-11 | Mauve Technology Limited | Disinfectant materials and methods |
| GB2477597A (en) * | 2010-02-03 | 2011-08-10 | Mauve Technology Ltd | Disinfectant materials and methods |
| ITTO20120327A1 (en) * | 2012-04-13 | 2013-10-14 | Duedi S R L | PROCEDURE FOR THE PRODUCTION OF A STABILIZED AQUEOUS CHLOROSSIDANT AQUEOUS SOLUTION AND AQUEOUS SOLUTION, A CHLOROSSIDANT STABILIZED SO PRODUCED |
| CN103300060A (en) * | 2013-05-31 | 2013-09-18 | 邵鹏飞 | Hydrogen peroxide solution and preparation method thereof |
| CN103300060B (en) * | 2013-05-31 | 2016-01-20 | 天津南药科技有限公司 | A kind of hydrogenperoxide steam generator and preparation method thereof |
| CN103749036B (en) * | 2014-01-09 | 2016-01-20 | 云南高山生物农业有限公司 | A kind of method for disinfection and sterilization of dendrobium candidum capsule |
| CN103749036A (en) * | 2014-01-09 | 2014-04-30 | 云南高山生物农业有限公司 | Method for sterilizing and disinfecting Dendrobium officinale capsules |
| EP3110248A4 (en) * | 2014-02-26 | 2017-09-20 | Disinfection Research LLC | Broad spectrum disinfectant |
| CN110523319A (en) * | 2019-08-27 | 2019-12-03 | 广州泰道安医疗科技有限公司 | A kind of disinfectant production technology |
| CN110523319B (en) * | 2019-08-27 | 2021-12-10 | 广州泰道安医疗科技有限公司 | Disinfectant fluid production process |
| EP3815532A1 (en) * | 2019-10-29 | 2021-05-05 | Wen Chung Shiao | Hypochlorous acid disinfectant and its production method |
| US11793200B2 (en) | 2019-10-29 | 2023-10-24 | Wen Chung Shiao | Hypochlorous acid disinfectant and its production method |
| US11638429B2 (en) | 2020-02-27 | 2023-05-02 | Super Aqua International Co., Ltd. | Hypochlorous acid disinfectant and its production method |
| US20240122971A1 (en) * | 2022-10-10 | 2024-04-18 | Wiab Water Innovation Ab | Compositions and methods for treatment and prevention of pathogens |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1293540A (en) | 2001-05-02 |
| AU2792400A (en) | 2000-09-21 |
| CN1264539A (en) | 2000-08-30 |
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