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WO2000050588A3 - Genes associes a des maladies du colon - Google Patents

Genes associes a des maladies du colon Download PDF

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Publication number
WO2000050588A3
WO2000050588A3 PCT/US2000/002595 US0002595W WO0050588A3 WO 2000050588 A3 WO2000050588 A3 WO 2000050588A3 US 0002595 W US0002595 W US 0002595W WO 0050588 A3 WO0050588 A3 WO 0050588A3
Authority
WO
WIPO (PCT)
Prior art keywords
colon
diseases
genes associated
provides
genes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/002595
Other languages
English (en)
Other versions
WO2000050588A2 (fr
Inventor
Michael G Walker
Wayne Volkmuth
Tod M Klingler
Preeti Lal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharmaceuticals Inc filed Critical Incyte Pharmaceuticals Inc
Priority to AU34797/00A priority Critical patent/AU3479700A/en
Priority to CA002361743A priority patent/CA2361743A1/fr
Priority to EP00913330A priority patent/EP1155126A2/fr
Priority to JP2000601152A priority patent/JP2002536995A/ja
Publication of WO2000050588A2 publication Critical patent/WO2000050588A2/fr
Publication of WO2000050588A3 publication Critical patent/WO2000050588A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne de gènes du cancer du côlon ainsi que des polypeptides encodés par ces gènes. L'invention concerne également des vecteurs d'expression, des cellules hôtes et des anticorps. L'invention concerne enfin des procédés pour le diagnostic, le traitement ou la prévention de maladies du côlon.
PCT/US2000/002595 1999-02-22 2000-02-01 Genes associes a des maladies du colon Ceased WO2000050588A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU34797/00A AU3479700A (en) 1999-02-22 2000-02-01 Genes associated with diseases of the colon
CA002361743A CA2361743A1 (fr) 1999-02-22 2000-02-01 Genes associes a des maladies du colon
EP00913330A EP1155126A2 (fr) 1999-02-22 2000-02-01 Genes associes a des maladies du colon
JP2000601152A JP2002536995A (ja) 1999-02-22 2000-02-01 結腸の疾患に関連する遺伝子

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25538199A 1999-02-22 1999-02-22
US09/255,381 1999-02-22

Publications (2)

Publication Number Publication Date
WO2000050588A2 WO2000050588A2 (fr) 2000-08-31
WO2000050588A3 true WO2000050588A3 (fr) 2000-12-14

Family

ID=22968072

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/002595 Ceased WO2000050588A2 (fr) 1999-02-22 2000-02-01 Genes associes a des maladies du colon

Country Status (5)

Country Link
EP (1) EP1155126A2 (fr)
JP (1) JP2002536995A (fr)
AU (1) AU3479700A (fr)
CA (1) CA2361743A1 (fr)
WO (1) WO2000050588A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124341B2 (en) 2002-06-06 2012-02-28 Oncotherapy Science, Inc. Genes and polypeptides relating to hepatocellular or colorectal carcinoma

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002077234A2 (fr) * 2000-10-31 2002-10-03 Diadexus, Inc. Compositions et methodes se rapportant aux genes et aux proteines specifiques du colon
AU2002243444A1 (en) * 2000-10-31 2002-06-24 Diadexus, Inc. Compositions and methods relating to colon specific genes and proteins
DE10061110B4 (de) * 2000-12-07 2006-12-21 Schaller, Gerhard, Prof. Dr. med. Expression der Keratingene 8 und 18 zur Therapie von Tumoren, insbesondere des Mammakarzinoms
ATE500326T1 (de) * 2002-06-06 2011-03-15 Oncotherapy Science Inc Gene und proteine mit bezug zu menschlichem kolonkrebs
EP1380644A1 (fr) * 2002-07-08 2004-01-14 Kylix B.V. Utilisation de gènes cible spécifiques de TCF pour identifier des medicaments pour le traitement du cancer, en particulier le cancer colorectal, dans lequel TCF/beta-catenin/WNT signalisation joue un rôle central
JP2007522791A (ja) * 2004-02-24 2007-08-16 オンコセラピー・サイエンス株式会社 結腸直腸癌を診断する方法
FR2919062B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'aminoacylase 1 pour le diagnostic in vitro du cancer colorectal.
FR2919065B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'apolipoproteine ai pour le diagnostic in vitro du cancer colorectal
FR2919064B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'apolipoproteine all pour le diagnostic in vitro du cancer colorectal
FR2919060B1 (fr) 2007-07-19 2012-11-30 Biomerieux Sa Procede de dosage de l'ezrine pour le diagnostic in vitro du cancer colorectal.
FR2919063B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal.
FR2919061B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de la plastine-i pour le diagnostic in vitro du cancer colorectal.
JP5715817B2 (ja) * 2007-07-19 2015-05-13 ビオメリューＢｉｏｍｅｒｉｅｕｘ 結腸直腸癌のインビトロ診断のための肝臓脂肪酸結合タンパク質、ｃｅａおよびｃａ１９−９のアッセイのための方法
FR2933773B1 (fr) 2008-07-10 2013-02-15 Biomerieux Sa Procede de dosage de la proteine disulfide isomerase pour le diagnostic in vitro du cancer colorectal
EP2221063A1 (fr) * 2009-02-20 2010-08-25 Ganymed Pharmaceuticals AG Procédé et compositions pour le diagnostic et le traitement du cancer
KR20110128316A (ko) 2009-02-20 2011-11-29 가니메드 파마슈티칼스 아게 암의 진단 및 치료를 위한 방법 및 조성물
NZ734307A (en) 2009-11-11 2020-05-29 Ganymed Pharmaceuticals Ag Antibodies specific for claudin 6 (cldn6)
EP2404936A1 (fr) 2010-07-06 2012-01-11 Ganymed Pharmaceuticals AG Thérapie du cancer utilisant des anticorps in vivo dirigés sur la cible CLDN6
CN107011440B (zh) 2011-05-13 2021-03-05 加尼梅德药物公司 用于治疗表达密蛋白6之癌症的抗体
WO2015014376A1 (fr) 2013-07-31 2015-02-05 Biontech Ag Diagnostic et thérapie du cancer impliquant des cellules souches cancéreuses

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EMBL Database Entry HSAA34446 Accession number AA134446; 7 December 1996 HILLIER L. ET AL *
JOHN C. KEEP ET AL.: "Immunophenotypic analysis of colorectal carcinomas with monoclonal antibodies 47D10 and anti.carcinoembryonic antigen", TUMOR BIOLOGY, vol. 10, 1989, pages 153 - 163, XP000920655 *
LADEANA HILLIER ET AL.: "Generation and analysis of 280,000 human expressed sequence tags", GENOME RESEARCH, vol. 6, no. 9, September 1996 (1996-09-01), pages 807 - 828, XP002140684 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124341B2 (en) 2002-06-06 2012-02-28 Oncotherapy Science, Inc. Genes and polypeptides relating to hepatocellular or colorectal carcinoma

Also Published As

Publication number Publication date
CA2361743A1 (fr) 2000-08-31
AU3479700A (en) 2000-09-14
WO2000050588A2 (fr) 2000-08-31
JP2002536995A (ja) 2002-11-05
EP1155126A2 (fr) 2001-11-21

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