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WO2000043028A3 - Method of treating chronic cardiac disease - Google Patents

Method of treating chronic cardiac disease Download PDF

Info

Publication number
WO2000043028A3
WO2000043028A3 PCT/US2000/001515 US0001515W WO0043028A3 WO 2000043028 A3 WO2000043028 A3 WO 2000043028A3 US 0001515 W US0001515 W US 0001515W WO 0043028 A3 WO0043028 A3 WO 0043028A3
Authority
WO
WIPO (PCT)
Prior art keywords
cardiac disease
chronic cardiac
treating chronic
disease
therapeutic uses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/001515
Other languages
French (fr)
Other versions
WO2000043028A2 (en
WO2000043028A9 (en
Inventor
Brett P Giroir
Patrick J Scannon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Xoma Technology Ltd USA
University of Texas at Austin
Original Assignee
University of Texas System
Xoma Technology Ltd USA
University of Texas at Austin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP00905696A priority Critical patent/EP1143996B1/en
Application filed by University of Texas System, Xoma Technology Ltd USA, University of Texas at Austin filed Critical University of Texas System
Priority to DE60002552T priority patent/DE60002552T2/en
Priority to AU27341/00A priority patent/AU778001B2/en
Priority to CA002359681A priority patent/CA2359681A1/en
Priority to JP2000594481A priority patent/JP2002535282A/en
Priority to AT00905696T priority patent/ATE239492T1/en
Priority to MXPA01007031A priority patent/MXPA01007031A/en
Priority to NZ513087A priority patent/NZ513087A/en
Publication of WO2000043028A2 publication Critical patent/WO2000043028A2/en
Publication of WO2000043028A3 publication Critical patent/WO2000043028A3/en
Anticipated expiration legal-status Critical
Publication of WO2000043028A9 publication Critical patent/WO2000043028A9/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1751—Bactericidal/permeability-increasing protein [BPI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

New therapeutic uses for BPI protein products that involve treatment of chronic cardiac disease.
PCT/US2000/001515 1999-01-22 2000-01-21 Method of treating chronic cardiac disease Ceased WO2000043028A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
NZ513087A NZ513087A (en) 1999-01-22 2000-01-21 Bactericidal/permability -increasing protein (BPI) for treating chronic heart disease
DE60002552T DE60002552T2 (en) 1999-01-22 2000-01-21 USE OF A BPI PROTEIN FOR PRODUCING A MEDICINAL PRODUCT FOR TREATING CHRONIC HEART DISEASES
AU27341/00A AU778001B2 (en) 1999-01-22 2000-01-21 Method of treating chronic cardiac disease
CA002359681A CA2359681A1 (en) 1999-01-22 2000-01-21 Method of treating chronic cardiac disease
JP2000594481A JP2002535282A (en) 1999-01-22 2000-01-21 How to treat chronic heart disease
EP00905696A EP1143996B1 (en) 1999-01-22 2000-01-21 Use of a bpi protein for the preparation of a medicament for treating chronic cardiac disease
MXPA01007031A MXPA01007031A (en) 1999-01-22 2000-01-21 Method of treating chronic cardiac disease.
AT00905696T ATE239492T1 (en) 1999-01-22 2000-01-21 USE OF A BPI PROTEIN TO PRODUCE A MEDICATION FOR THE TREATMENT OF CHRONIC HEART DISEASE

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11673699P 1999-01-22 1999-01-22
US60/116,736 1999-01-22

Publications (3)

Publication Number Publication Date
WO2000043028A2 WO2000043028A2 (en) 2000-07-27
WO2000043028A3 true WO2000043028A3 (en) 2000-11-30
WO2000043028A9 WO2000043028A9 (en) 2001-09-20

Family

ID=22368911

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/001515 Ceased WO2000043028A2 (en) 1999-01-22 2000-01-21 Method of treating chronic cardiac disease

Country Status (11)

Country Link
US (3) US6509317B1 (en)
EP (1) EP1143996B1 (en)
JP (2) JP2002535282A (en)
CN (1) CN1353614A (en)
AT (1) ATE239492T1 (en)
AU (1) AU778001B2 (en)
CA (1) CA2359681A1 (en)
DE (1) DE60002552T2 (en)
MX (1) MXPA01007031A (en)
NZ (1) NZ513087A (en)
WO (1) WO2000043028A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020173464A1 (en) 2000-12-01 2002-11-21 King George L. Modulation of pericyte proliferation
US20110002893A1 (en) * 2008-11-03 2011-01-06 Ut-Battelle, Llc Diagnosis and treatment of congenital heart defects using nell1
US9974759B2 (en) * 2013-05-31 2018-05-22 Indiana University Research And Technology Corporation Beta 2 adrenoceptor antagonists for treating orthostatic hypotension
GB201319621D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Antimicrobial agents and their use in therapy
GB201319620D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Immunosuppressive agents and their use in therapy
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578568A (en) * 1994-04-22 1996-11-26 Xoma Corporation Method of treating conditions associated with intestinal ischemia/reperfusion
US5643875A (en) * 1994-01-24 1997-07-01 Friedmann; Nadav Human therapeutic uses of bactericidal/permeability increasing (BPI) protein products
WO1997042966A1 (en) * 1996-05-10 1997-11-20 Xoma Corporation Therapeutic uses of bpi protein products for human meningococcemia

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646114A (en) * 1994-07-11 1997-07-08 Xoma Corporation Anti-protozoan methods

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643875A (en) * 1994-01-24 1997-07-01 Friedmann; Nadav Human therapeutic uses of bactericidal/permeability increasing (BPI) protein products
US5578568A (en) * 1994-04-22 1996-11-26 Xoma Corporation Method of treating conditions associated with intestinal ischemia/reperfusion
WO1997042966A1 (en) * 1996-05-10 1997-11-20 Xoma Corporation Therapeutic uses of bpi protein products for human meningococcemia

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BRISTOW M R ET AL: "DOSE-RESPONSE OF CHRONIC BETA-BLOCKER TREATMENT IN HEART FAILURE FROM EITHER IDIOPATHIC DILATED OR ISCHEMIC CARDIOMYOPATHY", CIRCULATION,US,AMERICAN HEART ASSOCIATION, DALLAS, TX, vol. 89, no. 4, April 1994 (1994-04-01), pages 1632 - 1642, XP000863212, ISSN: 0009-7322 *

Also Published As

Publication number Publication date
AU2734100A (en) 2000-08-07
EP1143996A4 (en) 2002-04-24
AU778001B2 (en) 2004-11-11
US6509317B1 (en) 2003-01-21
DE60002552T2 (en) 2004-02-26
US20030216312A1 (en) 2003-11-20
EP1143996A2 (en) 2001-10-17
US20060171937A1 (en) 2006-08-03
NZ513087A (en) 2003-02-28
JP2007126479A (en) 2007-05-24
WO2000043028A2 (en) 2000-07-27
JP2002535282A (en) 2002-10-22
WO2000043028A9 (en) 2001-09-20
EP1143996B1 (en) 2003-05-07
CA2359681A1 (en) 2000-07-27
DE60002552D1 (en) 2003-06-12
MXPA01007031A (en) 2004-08-12
US7045501B2 (en) 2006-05-16
ATE239492T1 (en) 2003-05-15
CN1353614A (en) 2002-06-12

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