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WO2000042191A3 - Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies - Google Patents

Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies Download PDF

Info

Publication number
WO2000042191A3
WO2000042191A3 PCT/EP2000/000135 EP0000135W WO0042191A3 WO 2000042191 A3 WO2000042191 A3 WO 2000042191A3 EP 0000135 W EP0000135 W EP 0000135W WO 0042191 A3 WO0042191 A3 WO 0042191A3
Authority
WO
WIPO (PCT)
Prior art keywords
neisseria meningitidis
antigenic polypeptides
protective antibodies
polypeptides
corresponding polynucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2000/000135
Other languages
French (fr)
Other versions
WO2000042191A2 (en
Inventor
Jean-Louis Ruelle
Joelle Thonnard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
SmithKline Beecham Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9900952.4A external-priority patent/GB9900952D0/en
Priority claimed from GBGB9901945.7A external-priority patent/GB9901945D0/en
Priority claimed from GBGB9901948.1A external-priority patent/GB9901948D0/en
Priority claimed from GBGB9902088.5A external-priority patent/GB9902088D0/en
Priority claimed from GBGB9902074.5A external-priority patent/GB9902074D0/en
Priority claimed from GBGB9902078.6A external-priority patent/GB9902078D0/en
Priority claimed from GBGB9902879.7A external-priority patent/GB9902879D0/en
Priority claimed from GBGB9902936.5A external-priority patent/GB9902936D0/en
Priority claimed from GBGB9903978.6A external-priority patent/GB9903978D0/en
Priority claimed from GBGB9904133.7A external-priority patent/GB9904133D0/en
Priority claimed from GBGB9904404.2A external-priority patent/GB9904404D0/en
Priority to CA002359504A priority Critical patent/CA2359504A1/en
Priority to EP00901524A priority patent/EP1144644A2/en
Priority to HK02102921.8A priority patent/HK1043151A1/en
Priority to AU22889/00A priority patent/AU2288900A/en
Application filed by SmithKline Beecham Biologicals SA filed Critical SmithKline Beecham Biologicals SA
Priority to JP2000593748A priority patent/JP2004537953A/en
Publication of WO2000042191A2 publication Critical patent/WO2000042191A2/en
Publication of WO2000042191A3 publication Critical patent/WO2000042191A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides Neisseria meningitidis BASB051, BASB057, BASB060, BASB061, BASB063, BASB065, BASB066 and BASB071 polypeptides, and polynucleotides encoding BASB051, BASB057, BASB060, BASB061, BASB063, BASB065, BASB066 and BASB071 polypeptides, and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses thereof.
PCT/EP2000/000135 1999-01-15 2000-01-10 Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies Ceased WO2000042191A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU22889/00A AU2288900A (en) 1999-01-15 2000-01-10 Novel compounds
HK02102921.8A HK1043151A1 (en) 1999-01-15 2000-01-10 Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies
EP00901524A EP1144644A2 (en) 1999-01-15 2000-01-10 Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies
CA002359504A CA2359504A1 (en) 1999-01-15 2000-01-10 Novel compounds
JP2000593748A JP2004537953A (en) 1999-01-15 2000-01-10 New compound

Applications Claiming Priority (24)

Application Number Priority Date Filing Date Title
GBGB9900952.4A GB9900952D0 (en) 1999-01-15 1999-01-15 Novel compounds
GB9900952.4 1999-01-15
GB9900838.5 1999-01-15
GB9900838 1999-01-15
GB9901945.7 1999-01-28
GB9901948.1 1999-01-28
GBGB9901948.1A GB9901948D0 (en) 1999-01-28 1999-01-28 Novel compounds
GBGB9901945.7A GB9901945D0 (en) 1999-01-28 1999-01-28 Novel compounds
GB9902078.6 1999-01-29
GBGB9902078.6A GB9902078D0 (en) 1999-01-29 1999-01-29 Novel compounds
GBGB9902074.5A GB9902074D0 (en) 1999-01-29 1999-01-29 Novel compounds
GBGB9902088.5A GB9902088D0 (en) 1999-01-29 1999-01-29 Novel compounds
GB9902074.5 1999-01-29
GB9902088.5 1999-01-29
GB9902879.7 1999-02-09
GBGB9902879.7A GB9902879D0 (en) 1999-02-09 1999-02-09 Novel compounds
GB9902936.5 1999-02-10
GBGB9902936.5A GB9902936D0 (en) 1999-02-10 1999-02-10 Novel compounds
GBGB9903978.6A GB9903978D0 (en) 1999-02-20 1999-02-20 Novel compounds
GB9903978.6 1999-02-20
GB9904133.7 1999-02-23
GBGB9904133.7A GB9904133D0 (en) 1999-02-23 1999-02-23 Novel compounds
GB9904404.2 1999-02-25
GBGB9904404.2A GB9904404D0 (en) 1999-02-25 1999-02-25 Novel compounds

Publications (2)

Publication Number Publication Date
WO2000042191A2 WO2000042191A2 (en) 2000-07-20
WO2000042191A3 true WO2000042191A3 (en) 2000-11-16

Family

ID=27583076

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/000135 Ceased WO2000042191A2 (en) 1999-01-15 2000-01-10 Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies

Country Status (6)

Country Link
EP (1) EP1144644A2 (en)
JP (1) JP2004537953A (en)
AU (1) AU2288900A (en)
CA (1) CA2359504A1 (en)
HK (1) HK1043151A1 (en)
WO (1) WO2000042191A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0103171D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
US20120070457A1 (en) * 2010-09-10 2012-03-22 J. Craig Venter Institute, Inc. Polypeptides from neisseria meningitidis
WO2013113917A1 (en) 2012-02-02 2013-08-08 Novartis Ag Promoters for increased protein expression in meningococcus

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998002547A2 (en) * 1996-07-12 1998-01-22 Institut National De La Sante Et De La Recherche Medicale (Inserm) Dna and specific proteins or peptides of the neisseria meningitidis species bacteria, method for obtaining them and their biological applications

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998002547A2 (en) * 1996-07-12 1998-01-22 Institut National De La Sante Et De La Recherche Medicale (Inserm) Dna and specific proteins or peptides of the neisseria meningitidis species bacteria, method for obtaining them and their biological applications

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DELAHAY RM ET AL: "Involvement of the gonococcal MtrE protein in the resistance of Neisseria gonorrhoeae to toxic hydrophobic agents", MICROBIOLOGY, vol. 143, no. 7, July 1997 (1997-07-01), pages 2127 - 2133, XP000907381 *
FUSSENEGGER M ET AL.: "A novel peptidoglycan-linked lipoprotein (ComL) that functions in natural transformation competence of Neisseria gonorrhoeae", MOLECULAR MICROBIOLOGY, vol. 19, no. 5, 1996, pages 1095 - 1105, XP000907394 *
MARTIN D ET AL: "HIGHLY CONSERVED NEISSERIA MENINGITIDIS SURFACE PROTEIN CONFERS PROTECTION AGAINST EXPERIMENTAL INFECTION", JOURNAL OF EXPERIMENTAL MEDICINE,JP,TOKYO, vol. 185, no. 7, 1997, pages 1173 - 1183-1183, XP000884332, ISSN: 0022-1007 *

Also Published As

Publication number Publication date
JP2004537953A (en) 2004-12-24
WO2000042191A2 (en) 2000-07-20
HK1043151A1 (en) 2002-09-06
EP1144644A2 (en) 2001-10-17
CA2359504A1 (en) 2000-07-20
AU2288900A (en) 2000-08-01

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