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WO1999038547A3 - Revetements pour implants medicaux presentant une biocompatibilite amelioree - Google Patents

Revetements pour implants medicaux presentant une biocompatibilite amelioree Download PDF

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Publication number
WO1999038547A3
WO1999038547A3 PCT/US1999/001766 US9901766W WO9938547A3 WO 1999038547 A3 WO1999038547 A3 WO 1999038547A3 US 9901766 W US9901766 W US 9901766W WO 9938547 A3 WO9938547 A3 WO 9938547A3
Authority
WO
WIPO (PCT)
Prior art keywords
coatings
medical implants
compound
anticlotting
enhanced biocompatibility
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/001766
Other languages
English (en)
Other versions
WO1999038547A2 (fr
Inventor
Michael Helmus
Michael J Scott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Priority to BR9908533-0A priority Critical patent/BR9908533A/pt
Priority to JP2000529278A priority patent/JP2002501789A/ja
Priority to AU24765/99A priority patent/AU2476599A/en
Priority to CA002318736A priority patent/CA2318736A1/fr
Priority to EP99904351A priority patent/EP1051210A2/fr
Publication of WO1999038547A2 publication Critical patent/WO1999038547A2/fr
Publication of WO1999038547A3 publication Critical patent/WO1999038547A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0017—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using a surface active agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

On décrit des revêtements pour implants médicaux présentant une biocompatibilité améliorée, des dispositifs médicaux à irradiation aiguë et des procédés de production desdits éléments. Ces revêtements biocompatibles sont particulièrement avantageuses lorsqu'ils sont utilisés en association avec des matériaux ayant une étendue de la surface élevée (résines poreuses, tissus et textiles, par exemple), et comprennent des complexes liés par migration des ions d'au moins un composé anticoagulant et d'au moins un composé d'ammonium quaternaire présentant plus de 0,15 et moins de 40 IU du composé anticoagulant par cm2. Ces sont produits par formation d'une solution du complexe ayant une concentration supérieure à 0,005 et inférieure à 1,5 p/v qu'on applique sur la surface et laisse sécher. Ces revêtements réduisent la propension au dépôt de thrombus sans nuire à la guérison ou à la croissance interne du tissu à l'intérieur du dispositif.
PCT/US1999/001766 1998-01-30 1999-01-28 Revetements pour implants medicaux presentant une biocompatibilite amelioree Ceased WO1999038547A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BR9908533-0A BR9908533A (pt) 1998-01-30 1999-01-28 Revestimento de biocompatibilidade melhorada para implantes médicos e dispositivos médicos de exposição aguda, processo para produção de um revestimento de biocompatibilidade melhorada, e, implante médico ou dispositivo médico de exposição aguda
JP2000529278A JP2002501789A (ja) 1998-01-30 1999-01-28 医療用インプラントのための生体適合性を増強したコーティング
AU24765/99A AU2476599A (en) 1998-01-30 1999-01-28 Enhanced biocompatibility coatings for medical implants
CA002318736A CA2318736A1 (fr) 1998-01-30 1999-01-28 Revetements pour implants medicaux presentant une biocompatibilite amelioree
EP99904351A EP1051210A2 (fr) 1998-01-30 1999-01-28 Revetements pour implants medicaux presentant une biocompatibilite amelioree

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1614798A 1998-01-30 1998-01-30
US09/016,147 1998-01-30

Publications (2)

Publication Number Publication Date
WO1999038547A2 WO1999038547A2 (fr) 1999-08-05
WO1999038547A3 true WO1999038547A3 (fr) 1999-09-23

Family

ID=21775639

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/001766 Ceased WO1999038547A2 (fr) 1998-01-30 1999-01-28 Revetements pour implants medicaux presentant une biocompatibilite amelioree

Country Status (6)

Country Link
EP (1) EP1051210A2 (fr)
JP (1) JP2002501789A (fr)
AU (1) AU2476599A (fr)
BR (1) BR9908533A (fr)
CA (1) CA2318736A1 (fr)
WO (1) WO1999038547A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060257355A1 (en) * 2005-05-10 2006-11-16 Abiomed, Inc. Impregnated polymer compositions and devices using them

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993005825A1 (fr) * 1991-09-20 1993-04-01 Baxter International Inc. Procedes permettant de reduire la thrombogenicite de biomateriaux
WO1993021860A1 (fr) * 1992-05-07 1993-11-11 Intervascular, Inc. Prothese vasculaire non thrombogene
US5679400A (en) * 1993-04-26 1997-10-21 Medtronic, Inc. Intravascular stent and method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993005825A1 (fr) * 1991-09-20 1993-04-01 Baxter International Inc. Procedes permettant de reduire la thrombogenicite de biomateriaux
WO1993021860A1 (fr) * 1992-05-07 1993-11-11 Intervascular, Inc. Prothese vasculaire non thrombogene
US5679400A (en) * 1993-04-26 1997-10-21 Medtronic, Inc. Intravascular stent and method

Also Published As

Publication number Publication date
AU2476599A (en) 1999-08-16
EP1051210A2 (fr) 2000-11-15
JP2002501789A (ja) 2002-01-22
BR9908533A (pt) 2000-11-28
WO1999038547A2 (fr) 1999-08-05
CA2318736A1 (fr) 1999-08-05

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