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WO1999047553A3 - Famille de polypeptides bacteriens - Google Patents

Famille de polypeptides bacteriens Download PDF

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Publication number
WO1999047553A3
WO1999047553A3 PCT/GB1999/000850 GB9900850W WO9947553A3 WO 1999047553 A3 WO1999047553 A3 WO 1999047553A3 GB 9900850 W GB9900850 W GB 9900850W WO 9947553 A3 WO9947553 A3 WO 9947553A3
Authority
WO
WIPO (PCT)
Prior art keywords
bacterial
yeal
targets
family members
drug design
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB1999/000850
Other languages
English (en)
Other versions
WO1999047553A2 (fr
Inventor
Fabrizio Arigoni
Michael David Edgerton
Hannes Loferer
Manuel C Peitsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to AU29473/99A priority Critical patent/AU2947399A/en
Priority to EP99910541A priority patent/EP1064301A1/fr
Priority to JP2000536744A priority patent/JP2002506628A/ja
Publication of WO1999047553A2 publication Critical patent/WO1999047553A2/fr
Anticipated expiration legal-status Critical
Publication of WO1999047553A3 publication Critical patent/WO1999047553A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne une famille de polypeptides bactériens de la famille des gènes yaeL. L'invention concerne également des gènes codant ces polypeptides, ainsi que l'utilisation de tels gènes et polypeptides comme outils d'identification de nouveaux antibiotiques à large spectre.
PCT/GB1999/000850 1998-03-18 1999-03-18 Famille de polypeptides bacteriens Ceased WO1999047553A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU29473/99A AU2947399A (en) 1998-03-18 1999-03-18 Bacterial polypeptide family
EP99910541A EP1064301A1 (fr) 1998-03-18 1999-03-18 Famille de polypeptides bacteriens
JP2000536744A JP2002506628A (ja) 1998-03-18 1999-03-18 細菌性ポリペプチドファミリー

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9805792.0A GB9805792D0 (en) 1998-03-18 1998-03-18 Bacterial polypeptide family
GB9805792.0 1998-03-18

Publications (2)

Publication Number Publication Date
WO1999047553A2 WO1999047553A2 (fr) 1999-09-23
WO1999047553A3 true WO1999047553A3 (fr) 2001-02-22

Family

ID=10828810

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1999/000850 Ceased WO1999047553A2 (fr) 1998-03-18 1999-03-18 Famille de polypeptides bacteriens

Country Status (5)

Country Link
EP (1) EP1064301A1 (fr)
JP (1) JP2002506628A (fr)
AU (1) AU2947399A (fr)
GB (1) GB9805792D0 (fr)
WO (1) WO1999047553A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002541820A (ja) * 1999-04-09 2002-12-10 ゲーペーツェー バイオテック アーゲー 抗菌性化合物を同定する新規な方法
EP1043403A1 (fr) * 1999-04-09 2000-10-11 GPC AG, Genome Pharmaceuticals Corporation Méthode pour l'identification des composés antibactériens

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996033276A1 (fr) * 1995-04-21 1996-10-24 Human Genome Sciences, Inc. Sequence nucleotidique du genome haemophilus influenzae rd, des fragments de ce dernier, ainsi que ses applications
WO1998019689A1 (fr) * 1996-11-01 1998-05-14 Smithkline Beecham Corporation Nouvelles sequences codantes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996033276A1 (fr) * 1995-04-21 1996-10-24 Human Genome Sciences, Inc. Sequence nucleotidique du genome haemophilus influenzae rd, des fragments de ce dernier, ainsi que ses applications
WO1998019689A1 (fr) * 1996-11-01 1998-05-14 Smithkline Beecham Corporation Nouvelles sequences codantes

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BAIROCH A. ET AL.: "The PROSITE database, its status in 1995", NUCLEIC ACID RESEARCH, vol. 24, no. 1, September 1993 (1993-09-01), pages 189 - 196, XP002108854 *
BLATTNER ET AL.: "Reference No.: A64720", ACCESSION H64741, 17 September 1997 (1997-09-17), XP002108437 *
BLATTNER ET AL.: "The complete genome sequence of Escherichia coli K-12", SCIENCE, vol. 277, no. 5331, 5 September 1997 (1997-09-05), pages 1453 - 1462 *
HENIKOFF S. AND HENIKOFF J.: "Performance Evaluation of Amino Acid Substitution Matrices", PROTEINS, vol. 17, no. 1, September 1993 (1993-09-01), pages 49 - 61, XP002108853 *
TATUSOV R. L. ET AL.: "The Genomic Perspective on Protein Families", SCIENCE, vol. 278, 24 October 1997 (1997-10-24), pages 631 - 637, XP002108438 *

Also Published As

Publication number Publication date
EP1064301A1 (fr) 2001-01-03
GB9805792D0 (en) 1998-05-13
AU2947399A (en) 1999-10-11
JP2002506628A (ja) 2002-03-05
WO1999047553A2 (fr) 1999-09-23

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