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WO1999046379A3 - Proteines receptrices humaines; reactifs et procedes associes - Google Patents

Proteines receptrices humaines; reactifs et procedes associes Download PDF

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Publication number
WO1999046379A3
WO1999046379A3 PCT/US1999/003735 US9903735W WO9946379A3 WO 1999046379 A3 WO1999046379 A3 WO 1999046379A3 US 9903735 W US9903735 W US 9903735W WO 9946379 A3 WO9946379 A3 WO 9946379A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
receptor proteins
human receptor
related reagents
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1999/003735
Other languages
English (en)
Other versions
WO1999046379A2 (fr
Inventor
Christi L Parham
Kevin W Moore
Nicholas J Murgolo
J Fernando Bazan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Priority to AU28718/99A priority Critical patent/AU2871899A/en
Priority to JP2000535746A priority patent/JP2002505879A/ja
Priority to CA002323236A priority patent/CA2323236A1/fr
Priority to EP99909534A priority patent/EP1062332A2/fr
Publication of WO1999046379A2 publication Critical patent/WO1999046379A2/fr
Publication of WO1999046379A3 publication Critical patent/WO1999046379A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des acides nucléiques codant pour des protéines réceptrices purifiées de mammifères, comme les rongeurs ou les primates, et des fragments de celles-ci. L'invention porte aussi sur des anticorps, polyclonaux et monoclonaux, ainsi que sur des procédés d'utilisation desdites compositions à des fins diagnostiques et thérapeutiques.
PCT/US1999/003735 1998-03-09 1999-03-08 Proteines receptrices humaines; reactifs et procedes associes Ceased WO1999046379A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU28718/99A AU2871899A (en) 1998-03-09 1999-03-08 Human receptor proteins; related reagents and methods
JP2000535746A JP2002505879A (ja) 1998-03-09 1999-03-08 ヒトレセプタータンパク質；関連する試薬および方法
CA002323236A CA2323236A1 (fr) 1998-03-09 1999-03-08 Proteines receptrices humaines; reactifs et procedes associes
EP99909534A EP1062332A2 (fr) 1998-03-09 1999-03-08 Proteines receptrices humaines; reactifs et procedes associes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3739498A 1998-03-09 1998-03-09
US09/037,394 1998-03-09

Publications (2)

Publication Number Publication Date
WO1999046379A2 WO1999046379A2 (fr) 1999-09-16
WO1999046379A3 true WO1999046379A3 (fr) 1999-10-21

Family

ID=21894109

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/003735 Ceased WO1999046379A2 (fr) 1998-03-09 1999-03-08 Proteines receptrices humaines; reactifs et procedes associes

Country Status (5)

Country Link
EP (1) EP1062332A2 (fr)
JP (1) JP2002505879A (fr)
AU (1) AU2871899A (fr)
CA (1) CA2323236A1 (fr)
WO (1) WO1999046379A2 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE485306T1 (de) * 1999-12-23 2010-11-15 Zymogenetics Inc Löslicher interleukin-20-rezeptor
DE60030769T2 (de) 1999-12-23 2007-10-25 Zymogenetics, Inc., Seattle Verfahren zur behandlung von entzündungen
US7122632B2 (en) 1999-12-23 2006-10-17 Zymogenetics, Inc. Soluble Interleukin-20 receptor
US6610286B2 (en) 1999-12-23 2003-08-26 Zymogenetics, Inc. Method for treating inflammation using soluble receptors to interleukin-20
DK1717316T3 (da) 2000-06-30 2008-12-08 Zymogenetics Inc Allelisk variant af interferon-lignende protein Zcyto21
US7045498B2 (en) 2000-08-08 2006-05-16 Zymogenetics, Inc. Soluble Zcytor11 cytokine receptors
ATE460429T1 (de) 2000-09-15 2010-03-15 Zymogenetics Inc Polypeptide enthaltend extrazellulären domäne von il-20ra und/oderr il-20rb
WO2003029262A2 (fr) * 2001-08-29 2003-04-10 Vanderbilt University Recepteurs de mob-5 humains (il-24) et utilisations de ceux-ci
EP1531843B1 (fr) 2001-12-17 2011-08-24 ZymoGenetics, Inc. Methode de traitement du cancer du col de l'uterus
CN103864934A (zh) 2003-03-24 2014-06-18 津莫吉尼蒂克斯公司 抗il-22ra抗体和结合伴侣以及在炎症中的使用方法
EP2251352A1 (fr) 2003-08-07 2010-11-17 ZymoGenetics, L.L.C. Préparations homogènes de IL-28 et IL-29
WO2005052000A2 (fr) 2003-11-21 2005-06-09 Zymogenetics, Inc. Anticorps et partenaires de liaison anti-il 20 et procedes d'utilisation dans l'inflammation
EP1812476B1 (fr) 2004-10-22 2010-07-21 ZymoGenetics, Inc. Anticorps anti-il-22ra et partenaires de liaison et methodes d'utilisation de ces anticorps et de ces partenaires de liaison pour le traitement de maladies inflammatoires
JP2013520476A (ja) 2010-02-26 2013-06-06 ノヴォ ノルディスク アー／エス 安定な抗体含有組成物
CN105055306B (zh) 2010-05-28 2019-10-01 诺沃—诺迪斯克有限公司 包含抗体和防腐剂的稳定的多剂量组合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005847A1 (fr) * 1993-08-20 1995-03-02 University Of Medicine & Dentistry Of New Jersey Fonction du facteur accessoire de l'interferon gamma et de son recepteur
WO1995016036A2 (fr) * 1993-12-09 1995-06-15 Michel Aguet CHAINE β DE RECEPTEURS D'IFN-η ET LEURS DERIVES

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005847A1 (fr) * 1993-08-20 1995-03-02 University Of Medicine & Dentistry Of New Jersey Fonction du facteur accessoire de l'interferon gamma et de son recepteur
WO1995016036A2 (fr) * 1993-12-09 1995-06-15 Michel Aguet CHAINE β DE RECEPTEURS D'IFN-η ET LEURS DERIVES

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002112563, Database accession no. AA455558 *
HEMMI S. ET AL.: "A novel member of the Interferon Receptor family complements functionality of the murine Interferon gamma Receptor in human cells", CELL, vol. 76, 11 March 1994 (1994-03-11), pages 803 - 810, XP002112561 *
PESTKA S.: "The Interferon Receptors", SEMINARS IN ONCOLOGY, vol. 24, no. 3 suppl. 9, June 1997 (1997-06-01), pages S9-18 - S9-40, XP002113151 *
SOH J. ET AL.: "Identification and sequence of an accessory factor required for activation of the human Interferon gamma Receptor", CELL, vol. 76, 11 March 1994 (1994-03-11), pages 793 - 802, XP002067347, ISSN: 0092-8674 *
ZUKER C. ET AL.: "Dictyostelium transposable element DIRS-1 has 350-base-pair inverted terminal repeats that contain a heat shock promoter", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, vol. 81, May 1984 (1984-05-01), pages 2660 - 2664, XP002112562 *

Also Published As

Publication number Publication date
AU2871899A (en) 1999-09-27
CA2323236A1 (fr) 1999-09-16
JP2002505879A (ja) 2002-02-26
WO1999046379A2 (fr) 1999-09-16
EP1062332A2 (fr) 2000-12-27

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