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WO1998036782A3 - Materiau de substitution de l'os, a revetement de surface a base de peptides ayant une sequence d'acides amines rgd - Google Patents

Materiau de substitution de l'os, a revetement de surface a base de peptides ayant une sequence d'acides amines rgd Download PDF

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Publication number
WO1998036782A3
WO1998036782A3 PCT/EP1998/000742 EP9800742W WO9836782A3 WO 1998036782 A3 WO1998036782 A3 WO 1998036782A3 EP 9800742 W EP9800742 W EP 9800742W WO 9836782 A3 WO9836782 A3 WO 9836782A3
Authority
WO
WIPO (PCT)
Prior art keywords
peptides
amino acid
acid sequence
bone substitute
surface coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1998/000742
Other languages
German (de)
English (en)
Other versions
WO1998036782A2 (fr
Inventor
Berthold Nies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Priority to PL98335103A priority Critical patent/PL335103A1/xx
Priority to AU61004/98A priority patent/AU6100498A/en
Priority to HU0000900A priority patent/HUP0000900A3/hu
Priority to CA002281608A priority patent/CA2281608A1/fr
Priority to JP53622098A priority patent/JP2001512344A/ja
Priority to EP98905418A priority patent/EP0968010A2/fr
Publication of WO1998036782A2 publication Critical patent/WO1998036782A2/fr
Publication of WO1998036782A3 publication Critical patent/WO1998036782A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne un matériau de substitution de l'os, à base d'un matériau polymérique poreux dont la surface est revêtue de peptides ayant une séquence d'acides aminés RGD.
PCT/EP1998/000742 1997-02-20 1998-02-11 Materiau de substitution de l'os, a revetement de surface a base de peptides ayant une sequence d'acides amines rgd Ceased WO1998036782A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
PL98335103A PL335103A1 (en) 1997-02-20 1998-02-11 Bone tissue substitute based on a porous polymeric material having its surface coated with peptides of rgd amino acid sequence
AU61004/98A AU6100498A (en) 1997-02-20 1998-02-11 Bone substitute material with a surface coating of peptides having an rgd amino acid sequence
HU0000900A HUP0000900A3 (en) 1997-02-20 1998-02-11 Bone substitute material with a surface coating of peptides having an rgd amino acid sequence, use thereof and method for preparation of this material
CA002281608A CA2281608A1 (fr) 1997-02-20 1998-02-11 Materiau de substitution de l'os, a revetement de surface a base de peptides ayant une sequence d'acides amines rgd
JP53622098A JP2001512344A (ja) 1997-02-20 1998-02-11 Ｒｇｄアミノ酸配列をもつペプチドの表面被覆を有する骨置換材
EP98905418A EP0968010A2 (fr) 1997-02-20 1998-02-11 Materiau de substitution de l'os, a revetement de surface a base de peptides ayant une sequence d'acides amines rgd

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19706667A DE19706667A1 (de) 1997-02-20 1997-02-20 Knochenersatzmaterial mit einer Oberflächenbelegung mit Peptiden mit RGD-Aminosäuresequenz
DE19706667.4 1997-02-20

Publications (2)

Publication Number Publication Date
WO1998036782A2 WO1998036782A2 (fr) 1998-08-27
WO1998036782A3 true WO1998036782A3 (fr) 1998-11-19

Family

ID=7820899

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/000742 Ceased WO1998036782A2 (fr) 1997-02-20 1998-02-11 Materiau de substitution de l'os, a revetement de surface a base de peptides ayant une sequence d'acides amines rgd

Country Status (11)

Country Link
EP (1) EP0968010A2 (fr)
JP (1) JP2001512344A (fr)
KR (1) KR20000075463A (fr)
CN (1) CN1247474A (fr)
AU (1) AU6100498A (fr)
CA (1) CA2281608A1 (fr)
DE (1) DE19706667A1 (fr)
HU (1) HUP0000900A3 (fr)
PL (1) PL335103A1 (fr)
WO (1) WO1998036782A2 (fr)
ZA (1) ZA981393B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002511496A (ja) 1998-04-13 2002-04-16 マサチューセッツ インスティテュート オブ テクノロジー 細胞表面相互作用を調節するためのコームコポリマー
DE19908318A1 (de) * 1999-02-26 2000-08-31 Michael Hoffmann Hämokompatible Oberflächen und Verfahren zu deren Herstellung
AU3556400A (en) 1999-03-17 2000-10-04 Novartis Ag Pharmaceutical compositions
DE19950386A1 (de) * 1999-10-19 2001-05-10 Miladin Lazarov Biokompatibler Gegenstand
GB0108767D0 (en) * 2001-04-07 2001-05-30 Univ Leeds Coatings
DE10119096A1 (de) * 2001-04-19 2002-10-24 Keramed Medizintechnik Gmbh Biologisch funktionalisierte, metabolisch induktive Implantatoberflächen
KR20040032297A (ko) * 2002-10-09 2004-04-17 (주)아미티에 생분해성 골접합용 코팅 임플란트
NL1023602C2 (nl) * 2003-06-05 2004-12-07 Univ Eindhoven Tech Werkwijze voor het bereiden van een aminozuren bevattende oplossing en de toepassing van een dergelijke oplossing.
KR101013999B1 (ko) * 2004-03-19 2011-02-14 재단법인서울대학교산학협력재단 표면에 골조직 형성 증진 펩타이드가 고정된 차폐막 및임플란트
US8696564B2 (en) 2004-07-09 2014-04-15 Cardiac Pacemakers, Inc. Implantable sensor with biocompatible coating for controlling or inhibiting tissue growth
DE102004043908A1 (de) * 2004-09-10 2006-03-30 GRÄTER, Stefan Oberflächenstrukturierte polymere Substrate und ihre Herstellung
FR2876916B1 (fr) * 2004-10-25 2007-01-05 Midi Pyrenees Incubateur Produit implantable de surface fonctionnalisee au moyen de dendrimeres a terminaisons anioniques
KR100676945B1 (ko) * 2005-03-18 2007-02-01 재단법인서울대학교산학협력재단 표면에 골조직 형성 증진 펩타이드가 고정된 골이식재 및 조직공학용 지지체
DE102006047248B4 (de) * 2006-10-06 2012-05-31 Celgen Ag Dreidimensionale künstliche Kallusdistraktion
CN101006944B (zh) * 2007-01-31 2010-06-09 浙江大学 一种在多孔纯钛牙种植体表面组装rgd的方法
DE102009042493B4 (de) 2009-09-14 2016-07-21 Celgen3D Ag Granulatmischung, umfassend zwei verschiedene Granulate, zur künstlichen Kallusdistraktion
CN102716513B (zh) * 2012-05-02 2014-12-24 清华大学 一种在钙磷陶瓷材料表面修饰rgd的方法
GB2503950A (en) * 2012-07-14 2014-01-15 Nobel Biocare Services Ag An agent for promoting osseointegration of bone substitute materials
US20150224224A1 (en) * 2012-07-14 2015-08-13 Nobel Biocare Services Ag Bioactivated material
CN103845759A (zh) * 2014-03-14 2014-06-11 国家纳米科学中心 一种组织工程界面修饰材料、其修饰方法及应用
CN104474590A (zh) * 2014-12-12 2015-04-01 北京博恩康生物科技有限公司 一种可注射活性骨修复材料及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4756862A (en) * 1977-04-14 1988-07-12 Amoco Corporation Prosthetic devices having coatings of selected porous bioengineering thermoplastics
US5330911A (en) * 1989-09-28 1994-07-19 Board Of Regents, The University Of Texas System Surfaces having desirable cell adhesive effects
WO1995019796A1 (fr) * 1994-01-21 1995-07-27 Brown University Research Foundation Implants biocompatibles

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4756862A (en) * 1977-04-14 1988-07-12 Amoco Corporation Prosthetic devices having coatings of selected porous bioengineering thermoplastics
US5330911A (en) * 1989-09-28 1994-07-19 Board Of Regents, The University Of Texas System Surfaces having desirable cell adhesive effects
WO1995019796A1 (fr) * 1994-01-21 1995-07-27 Brown University Research Foundation Implants biocompatibles

Also Published As

Publication number Publication date
CN1247474A (zh) 2000-03-15
JP2001512344A (ja) 2001-08-21
EP0968010A2 (fr) 2000-01-05
AU6100498A (en) 1998-09-09
KR20000075463A (ko) 2000-12-15
ZA981393B (en) 1998-08-24
WO1998036782A2 (fr) 1998-08-27
HUP0000900A2 (hu) 2000-10-28
DE19706667A1 (de) 1998-08-27
CA2281608A1 (fr) 1998-08-27
HUP0000900A3 (en) 2000-12-28
PL335103A1 (en) 2000-04-10

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