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WO1998033433A1 - Procede et appareil permettant de traiter les troubles des voies respiratoires - Google Patents

Procede et appareil permettant de traiter les troubles des voies respiratoires Download PDF

Info

Publication number
WO1998033433A1
WO1998033433A1 PCT/US1998/001987 US9801987W WO9833433A1 WO 1998033433 A1 WO1998033433 A1 WO 1998033433A1 US 9801987 W US9801987 W US 9801987W WO 9833433 A1 WO9833433 A1 WO 9833433A1
Authority
WO
WIPO (PCT)
Prior art keywords
pressure
flow
blower
sleep apnea
sensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1998/001987
Other languages
English (en)
Inventor
John L. Servidio
Don Griffin
Gregg Hurst
Robert Andersen
Erik Moore
Venkata Katragadda
Niki R. Pantelias
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Respironics Georgia Inc
Original Assignee
Respironics Georgia Inc
Healthdyne Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Respironics Georgia Inc, Healthdyne Technologies Inc filed Critical Respironics Georgia Inc
Priority to AU62629/98A priority Critical patent/AU6262998A/en
Publication of WO1998033433A1 publication Critical patent/WO1998033433A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A61M16/0066—Blowers or centrifugal pumps
    • A61M16/0069—Blowers or centrifugal pumps the speed thereof being controlled by respiratory parameters, e.g. by inhalation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A61M16/024—Control means therefor including calculation means, e.g. using a processor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0816—Joints or connectors
    • A61M16/0841—Joints or connectors for sampling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0816—Joints or connectors
    • A61M16/0841—Joints or connectors for sampling
    • A61M16/0858—Pressure sampling ports
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/0823—Detecting or evaluating cough events
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3561—Range local, e.g. within room or hospital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/42—Reducing noise

Definitions

  • This invention relates generally to a device for treating airway disorders and more particularly to an apparatus for treating obstructive sleep apnea which utilizes a variable speed blower in combination with control features utilizing correction factors for elements located within the apparatus for maintaining an
  • the treatment of airway disorders such as obstructive sleep apnea involves subjecting a patient to a positive pressure flow of air.
  • Such methods include providing continuous positive airway pressure (CPAP) and bi-level positive airway pressure treatment which incorporate a presentation of positive air pressure to the airways of a patient.
  • CPAP continuous positive airway pressure
  • Bi-level treatment involves presenting a high pressure to the patient during inhalation and a lower pressure during exhalation.
  • apnea include incorporating pressure control devices and flow metering devices into the
  • the accuracy of the pressure and flow metering devices is critical to ensure the correct operation of the sleep apnea treatment system. Due to the inconsistencies of the operational mechanics of these devices resulting from the manufacturing of the devices, a
  • CPAP and bi-level positive airway pressure devices have been created. However, such devices tend to be expensive. Accordingly, a need arises for a low cost device making it economical for people suffering from obstructive sleep apnea to have
  • apnea treatment device Additionally, it is an object of the present invention to provide correction factors for ensuring the reliable operation of sleep apnea treatment devices;
  • the above objectives are accomplished according to the present invention by providing a device for the treatment of sleep apnea.
  • the device includes a variable-speed blower for providing an airflow under pressure to a patient for treating sleep apnea.
  • a motor controller is interconnected with the variable speed blower for manipulating the speed of the blower for providing air at a predetermined pressure.
  • a flow meter assembly is inline between the variable speed blower and a patient for receiving the airflow.
  • the flow meter assembly includes a flow port for communicating a portion of the airflow to a
  • the flow meter assembly also includes a pressure port in communication with a pressure sensor for monitoring the pressure of the
  • An input device enables the inputting of the desired pressure of the airflow.
  • a microprocessor receives the inputted desired pressure and the flow measured by the flow sensor and the pressure measured by the pressure sensor. The microprocessor controls the
  • FIG. 1 is an exploded view of a sleep apnea treatment device according to the present invention
  • FIG. 2 is a perspective view of a flow meter assembly according to the present
  • FIG. 3 is an exploded view of a flow meter assembly according to the present invention
  • FIG. 4 is an operational schematic of a flow meter assembly according to the present invention
  • FIG. 5 is an operational schematic of a patient monitoring system utilized in a sleep
  • FIG. 6 is an operational schematic of a sleep apnea treatment device according to the present invention.
  • FIG. 7 is an operational schematic of a sleep apnea treatment device according to
  • FIG. 8 is a diagram illustrating application of rise time according to the present
  • FIG. 9 is a diagram illustrating application of fall time according to the present
  • sleep apnea treatment device A includes a general housing
  • circuit board 16 carries microprocessor 18, which among other features described hereinafter, manipulates the operation of variable speed blower 12 depending on the flow and pressure values measured by flow meter assembly 14 .
  • the speed of variable speed blower 12 produces pressurized air which is communicated to a patient through a conduit interconnected with flow meter assembly 14 for treating sleep apnea.
  • sleep apnea treatment device A may provide different pressure levels of pressurized air to a patient depending on whether the patient is inhaling or exhaling.
  • Such variation in pressure levels is known as bi-level treatment wherein a higher level of positive airway pressure is supplied during inhalation and a lower level of positive airway pressure is supplied during exhalation.
  • Flow meter assembly 14 is shown in FIGs. 2, 3 and 4. Flow meter assembly 14
  • blower connection member 20 for mounting flow meter assembly 14 in fluid communication with outlet 22 of variable speed blower 12 for receiving pressurized air.
  • First flow meter center member 24 receives pressurized air from blower connection
  • First screen 26 is disposed between blower connection member 20 and first flow meter center member 24 for removing airflow disruptions and creating a smooth airflow.
  • First flow meter center member 24 carries flow sensor port 28 for directing
  • Second flow meter center member 32 is interconnected with first flow meter center member 24 for receiving pressurized air. Second flow meter center
  • Second screen 36 is
  • first and second flow meter center members 24 and 32 disposed between first and second flow meter center members 24 and 32 for creating a pressure drop between the two center members thereby influencing airflow to pass through
  • Flow meter assembly 14 further includes flow meter outlet member 38 for directing the pressurized airflow to a conduit for presentation to a patient.
  • outlet member 38 includes pressure port 40 which is interconnected with pressure sensor 42 which is preferably a transducer for determining the pressure of airflow through the sleep apnea treatment system.
  • Third screen 44 is disposed between second flow meter center member 32 and flow meter outlet member 38 for removing airflow disruptions and creating a smooth airflow when airflow is negative
  • the respective members of flow meter assembly 14 each include interior portions
  • Flow sensor 30 monitors the air flow through sleep apnea treatment system A.
  • flow sensor 30 is preferably a flow transducer of a mass airflow type producing an analog voltage signal. Accordingly, flow transducer 30 operates on a flow versus voltage relationship.
  • mass airflow transducers due to the inherent operational characteristics of mass airflow transducers, a particular change in flow value does not always produce the
  • flow tests are conducted on flow transducer 30.
  • the tests entail simultaneously presenting an airflow through a control flow transducer and flow transducer 30. While the airflow is presented, the corresponding voltage is measured by flow transducer 30 at one millisecond intervals for sixty-four milliseconds producing sixty-four sampled values which are averaged to produce an average voltage value for flow transducer 30 at that particular airflow value. Also, the flow value
  • control flow versus mass airflow flow transducer recorded voltage relationship table is produced.
  • sixteen pairs of flow points are calculated at sixteen different airflow levels, preferably those airflow levels which produce flow
  • a fourth order polynomial is created utilizing a Chebyshev polynomial regression technique on the established flow relationship table.
  • the Chebyshev regression is used to produce the
  • coefficients C 0 , C ls C 2 , C 3 and C 4 are calculated for that specific flow transducer. These coefficient values are stored on EEPROM 46 as a flow calibration model 48 and accessed during operation of flow transducer 30 for producing a flow value indicative of the flow through sleep apnea
  • the flow value is utilized during inspiration/exhalation detection as
  • Pressure sensor 42 is preferably a
  • pressure transducer 42 is tested at different temperatures with respect to a control pressure transducer to determine the offset coefficient b at different temperatures for that particular pressure transducer.
  • coefficient b and temperature can be approximated as linear enabling a linear profile of b versus temperature over a range of temperatures to be created.
  • the offset coefficient b is calculated at three temperatures: b at 25 °C; b at 40°C; and b at 55 °C and a linear pressure/temperature profile is created for temperatures in between.
  • This pressure/temperature profile 52 is stored in EEPROM 46 for the
  • a large correction factor is stored EEPROM 46 and then set in a digital potentiometer as b pot such that offset coefficient b consists of b pot + b at the respective temperature.
  • temperature sensor 54 is located adjacent pressure transducer 42 on printed circuit board 16. Accordingly, microprocessor 18 utilizes the temperature reading from temperature sensor 54 in combination with the
  • pressure transducer 42 pressure/temperature profile 52 for establishing a temperature corrected pressure value.
  • This temperature corrected pressure value is utilized for controlling blower 12 in delivering the required treatment air pressures to a patient.
  • pressure transducer 42 may require further calibration. This is accomplished by auto
  • an auto-zero correction factor 56 is calculated to adjust the pressure value to zero. This auto-zero correction factor 56 is utilized by microprocessor 18 in
  • the auto-zero factor is calculated each time sleep apnea treatment device A is initially powered up.
  • patient monitoring system 58 monitors the utilization of sleep apnea treatment device A by a patient.
  • microprocessor 18 As shown in FIGs. 6 and 7, microprocessor 18
  • the first time event noted is when sleep apnea treatment device A is initially powered up. This time is recorded in a log in EEPROM 46.
  • Patient monitoring system 58 also monitors if a patient is breathing on the system. If breaths in a range between four to forty breaths per minute are detected, it is assumed that a patient is utilizing the system. At this event, the time is noted and a
  • the total time that the machine is used by the patient is stored in a
  • sleep apnea treatment device A also includes an optical transmitter 70 and a optical receiver 72. These devices utilize light waves to enable sleep apnea treatment device A to be manipulated by remote control and also allows a recording receiving device to monitor the operations of sleep apnea treatment device A for analyzing
  • the device A may be monitored by the remote recording device for further analysis of the sleep apnea treatment for that particular patient.
  • a rise time feature 74 may be selected by the
  • rise time feature 74 defines a profile in the rise of pressure from the lower exhalation pressure to the higher inhalation pressure when the sleep apnea treatment device A switches from exhalation to inhalation pressure for the treatment of sleep apnea.
  • Rise time includes two separate parameters. The first parameter is the time during which the exhalation pressure increases to the inhalation pressure during a single
  • a particular pressure is presented at a particular time. For instance, if the exhalation pressure is five cm H 2 O and the inhalation pressure is ten cm H 2 O, the five cm H 2 O pressure differential is provided to the patient over the selected time period such that a particular pressure i.e., six point two, seven point two, and eight point
  • a fall time exponential profile is provided such that the inhalation pressure drops to the exhalation pressure within point four seconds.
  • the exponential utilizes the inhalation pressure and the exhalation pressure's parameters for
  • sleep apnea treatment device A includes a baffling system for muffling the noise of blower 12. As shown in FIG. 1, the housing includes air inlet 80 wherein air is drawn from the ambient environment by blower 12. The air is presented to
  • Baffle passageway 82 includes a blower baffle chamber 84 which
  • a first generally perpendicular passage 86 extends from blower baffle chamber 84 a general distance and then is directed to a second generally perpendicular passageway 88 and then is directed to a third generally perpendicular passageway 90 and ultimately to a fourth
  • baffle passageway 82 facilitates in distorting the noise created by blower 12 and also forces the noise upward.
  • the baffle passageway 82 is enclosed by bottom housing 94 and at the top by blower motor mounting plate 96 which encloses the top of baffle passageway 82.
  • Blower mounting plate 96 includes blower port 98 enabling the lower portion of blower 12
  • blower baffle chamber 84 for receiving air from the
  • Sound filter 100 is disposed between blower mounting plate and baffle passageway 82 for absorbing sound waves which have been directed upward from baffle chamber walls. Furthermore, disposed between air inlet 80 and the entrance of baffle passageway 82 is vertical baffle 102 which directs sound waves vertically for being
  • sleep apnea treatment device A mechanically includes a variable speed blower 12 having a variable speed motor 62 which is controlled by a motor driver 64 for varying the speed of the blower.
  • the blower 12 has a variable speed motor 62 which is controlled by a motor driver 64 for varying the speed of the blower.
  • the flow meter assembly 14 includes ports to enable the
  • Sleep apnea treatment device A may be a bi-level machine wherein a higher
  • variable speed blower may be continuously varied during operation of sleep apnea treatment device A to provide varying pressures for the treatment of sleep apnea.
  • FIGs. 6 and 7, illustrates schematically the operation of sleep apnea treatment device A.
  • Microprocessor 18 controls motor driver 64 which controls a three phase
  • brushless motor 62 which manipulates blower 12 to provide pressurized air to the patient.
  • the air passes through flow meter assembly 14 which sends air to flow sensor 30 which sends a signal to microprocessor 18.
  • Microprocessor 18 utilizes flow calibration model 48 for calculating the air flow.
  • Temperature sensor 54 located adjacent to pressure sensor 42 sends a temperature reading to microprocessor 18 for use in calculating a calibrated
  • Pressure sensor 32 sends a pressure signal to microprocessor 18 which converts the pressure utilizing that pressure conversion factor for that particular pressure transducer and also utilizing the auto offset calibration 56
  • the inhalation exhalation detection sub-module is utilized for determining the amount of
  • microprocessor 18 and any fluctuation between the actual pressure measured and that
  • treatment pressure which is intended to be provided, is utilized for controlling the motor driver 64 for varying the speed of the motor 62 of the blower 12 to provide the desired pressure.
  • the operation of sleep apnea treatment device A is monitored by the patient compliance system 58 for monitoring the utilization of the system by the patient.
  • a patient may be had according to the present invention.
  • a low cost but reliable system may be had by establishing correction factors for pressure transducers and flow sensors to ensure the accurate operation of the sleep apnea treatment device wherein a variable speed blower may be manipulated on the readings from a single flow meter device for providing positive air pressure treatment to a patient.

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  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

Dispositif (A) permettant de traiter l'apnée du sommeil et comportant une soufflante à vitesse variable (12) commandée par ordinateur (18), ainsi qu'un débitmètre (14), fournissant des données relatives à l'écoulement d'air et à la pression à l'ordinateur destiné à commander la soufflante.
PCT/US1998/001987 1997-01-31 1998-01-30 Procede et appareil permettant de traiter les troubles des voies respiratoires Ceased WO1998033433A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU62629/98A AU6262998A (en) 1997-01-31 1998-01-30 Method and apparatus for treating airway disorders

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3640797P 1997-01-31 1997-01-31
US60/036,407 1997-01-31

Publications (1)

Publication Number Publication Date
WO1998033433A1 true WO1998033433A1 (fr) 1998-08-06

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Application Number Title Priority Date Filing Date
PCT/US1998/001987 Ceased WO1998033433A1 (fr) 1997-01-31 1998-01-30 Procede et appareil permettant de traiter les troubles des voies respiratoires

Country Status (2)

Country Link
AU (1) AU6262998A (fr)
WO (1) WO1998033433A1 (fr)

Cited By (35)

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Publication number Priority date Publication date Assignee Title
US6532959B1 (en) * 1998-05-22 2003-03-18 Resmed, Ltd. Ventilatory assistance for treatment of cardiac failure and cheyne-stokes breathing
WO2003049793A3 (fr) * 2001-12-12 2003-11-06 Seleon Gmbh Procede de regulation de la pression differentielle dans un appareil a ventilation spontanee en pression positive continue et appareil a ventilation spontanee en pression positive continue associe
EP1110573A3 (fr) * 1999-12-23 2003-12-03 MAP Medizintechnik für Arzt und Patient GmbH & Co. KG Dispositif d'alimentation en gaz respiratoire
EP1231965A4 (fr) * 1999-11-01 2004-08-04 Respironics Inc Procede et appareil permettant de surveiller et commander un dispositif medical
WO2004108198A1 (fr) * 2003-06-10 2004-12-16 Resmed Limited Respirateur a plusieurs etages et boitier associe
US6889692B2 (en) 1996-10-16 2005-05-10 Resmed Limited Vent valve assembly
US6910483B2 (en) 2001-12-10 2005-06-28 Resmed Limited Double-ended blower and volutes therefor
US7137389B2 (en) 1996-09-23 2006-11-21 Resmed Limited Method and apparatus for determining instantaneous inspired volume of a subject during ventilatory assistance
US7302950B2 (en) 1991-12-20 2007-12-04 Resmed Limited Patient interface for respiratory apparatus
US7938112B2 (en) 1999-08-05 2011-05-10 Map Medizin-Technologie Gmbh Apparatus for humidifying a respiratory gas
USRE44453E1 (en) 2001-02-16 2013-08-27 Resmed Limited Humidifier with structure to prevent backflow of liquid through the humidifier inlet
US8517012B2 (en) 2001-12-10 2013-08-27 Resmed Limited Multiple stage blowers and volutes therefor
US8789525B2 (en) 2007-06-07 2014-07-29 Resmed Limited Tub for humidifier
US9038632B2 (en) 2003-06-20 2015-05-26 Resmed Limited Breathable gas apparatus with humidifier
US9610416B2 (en) 2009-06-04 2017-04-04 Resmed Limited Flow generator chassis assembly with suspension seal
EP3195892A1 (fr) * 2011-08-05 2017-07-26 ResMed Motor Technologies Inc Dispositif de ventilation à pression positive
US10061899B2 (en) 2008-07-09 2018-08-28 Baxter International Inc. Home therapy machine
US10173008B2 (en) 2002-01-29 2019-01-08 Baxter International Inc. System and method for communicating with a dialysis machine through a network
US10293125B2 (en) 2003-06-20 2019-05-21 Resmed Limited Flow generator with patient reminder
US10347374B2 (en) 2008-10-13 2019-07-09 Baxter Corporation Englewood Medication preparation system
US10646405B2 (en) 2012-10-26 2020-05-12 Baxter Corporation Englewood Work station for medical dose preparation system
US10806889B2 (en) 2008-06-05 2020-10-20 ResMed Pty Ltd Treatment of respiratory conditions
US10818387B2 (en) 2014-12-05 2020-10-27 Baxter Corporation Englewood Dose preparation data analytics
US10971257B2 (en) 2012-10-26 2021-04-06 Baxter Corporation Englewood Image acquisition for medical dose preparation system
US11107574B2 (en) 2014-09-30 2021-08-31 Baxter Corporation Englewood Management of medication preparation with formulary management
FR3110435A1 (fr) * 2020-05-20 2021-11-26 Renault S.A.S Agencement d’un dispositif d’assistance à la respiration
US11367533B2 (en) 2014-06-30 2022-06-21 Baxter Corporation Englewood Managed medical information exchange
US11400247B2 (en) 2016-12-22 2022-08-02 Fisher & Paykel Healthcare Limited Breathing assistance apparatus
US11497867B2 (en) 2016-12-09 2022-11-15 Trudell Medical International Smart nebulizer
US11575673B2 (en) 2014-09-30 2023-02-07 Baxter Corporation Englewood Central user management in a distributed healthcare information management system
US11666801B2 (en) 2018-01-04 2023-06-06 Trudell Medical International Smart oscillating positive expiratory pressure device
US11712175B2 (en) 2019-08-27 2023-08-01 Trudell Medical International Smart oscillating positive expiratory pressure device with feedback indicia
US11839716B2 (en) 2016-07-08 2023-12-12 Trudell Medical International Smart oscillating positive expiratory pressure device
US11948112B2 (en) 2015-03-03 2024-04-02 Baxter Corporation Engelwood Pharmacy workflow management with integrated alerts
US12412644B2 (en) 2014-10-24 2025-09-09 Baxter Corporation Englewood Automated exchange of healthcare information for fulfillment of medication doses

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Cited By (103)

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Publication number Priority date Publication date Assignee Title
US7302950B2 (en) 1991-12-20 2007-12-04 Resmed Limited Patient interface for respiratory apparatus
US8733351B2 (en) 1996-09-23 2014-05-27 Resmed Limited Method and apparatus for providing ventilatory assistance
US9974911B2 (en) 1996-09-23 2018-05-22 Resmed Limited Method and apparatus for providing ventilatory assistance
US7137389B2 (en) 1996-09-23 2006-11-21 Resmed Limited Method and apparatus for determining instantaneous inspired volume of a subject during ventilatory assistance
US6889692B2 (en) 1996-10-16 2005-05-10 Resmed Limited Vent valve assembly
US7059325B2 (en) 1996-10-16 2006-06-13 Resmed Limited Vent assembly
US9770571B2 (en) 1996-10-16 2017-09-26 Resmed Limited Vent valve assembly
US8997739B2 (en) 1996-10-16 2015-04-07 Resmed Limited Vent valve apparatus
US6532959B1 (en) * 1998-05-22 2003-03-18 Resmed, Ltd. Ventilatory assistance for treatment of cardiac failure and cheyne-stokes breathing
US8857430B2 (en) 1998-05-22 2014-10-14 Resmed Limited Ventilatory assistance for treatment of cardiac failure and cheyne-stokes breathing
US8528556B2 (en) 1998-05-22 2013-09-10 Resmed Limited Ventilatory assistance for treatment of cardiac failure and cheyne-stokes breathing
US6951217B2 (en) 1998-05-22 2005-10-04 Resmed Limited Ventilatory assistance for treatment of cardiac failure and cheyne-stokes breathing
US9884163B2 (en) 1999-08-05 2018-02-06 RedMed R&D Germany GmbH Apparatus for humidifying a respiratory gas
US9272116B2 (en) 1999-08-05 2016-03-01 Resmed R&D Germany Gmbh Apparatus for humidifying a respiratory gas
US9545493B2 (en) 1999-08-05 2017-01-17 Resmed R&D Germany Gmbh Apparatus for humidifying a respiratory gas
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