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WO1998032847A3 - Characterization of the yeast transcriptome - Google Patents

Characterization of the yeast transcriptome Download PDF

Info

Publication number
WO1998032847A3
WO1998032847A3 PCT/US1998/001216 US9801216W WO9832847A3 WO 1998032847 A3 WO1998032847 A3 WO 1998032847A3 US 9801216 W US9801216 W US 9801216W WO 9832847 A3 WO9832847 A3 WO 9832847A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell
cell cycle
characterization
transcriptome
yeast transcriptome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1998/001216
Other languages
French (fr)
Other versions
WO1998032847A2 (en
Inventor
Victor E Velculescu
Bert Vogelstein
Kenneth W Kinzler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Priority to CA002278645A priority Critical patent/CA2278645A1/en
Priority to EP98902680A priority patent/EP0970202A2/en
Priority to AU59280/98A priority patent/AU749606C/en
Priority to JP53211798A priority patent/JP2001509017A/en
Publication of WO1998032847A2 publication Critical patent/WO1998032847A2/en
Publication of WO1998032847A3 publication Critical patent/WO1998032847A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Yeast genes which are differentially expressed during the cell cycle are described. They can be used to study, affect, and monitor the cell cycle of a eukaryotic cell. They can be used to obtain human homologs involved in cell cycle regulation. They can be used to identify antifungal agents. They can be formed into arrays on solid supports for interrogation of a cell's transcriptome under various conditions.
PCT/US1998/001216 1997-01-23 1998-01-22 Characterization of the yeast transcriptome Ceased WO1998032847A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002278645A CA2278645A1 (en) 1997-01-23 1998-01-22 Characterization of the yeast transcriptome
EP98902680A EP0970202A2 (en) 1997-01-23 1998-01-22 Characterization of the yeast transcriptome
AU59280/98A AU749606C (en) 1997-01-23 1998-01-22 Characterization of the yeast transcriptome
JP53211798A JP2001509017A (en) 1997-01-23 1998-01-22 East transcriptome characterization

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3591797P 1997-01-23 1997-01-23
US60/035,917 1997-01-23

Publications (2)

Publication Number Publication Date
WO1998032847A2 WO1998032847A2 (en) 1998-07-30
WO1998032847A3 true WO1998032847A3 (en) 1998-11-26

Family

ID=21885540

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/001216 Ceased WO1998032847A2 (en) 1997-01-23 1998-01-22 Characterization of the yeast transcriptome

Country Status (5)

Country Link
EP (1) EP0970202A2 (en)
JP (1) JP2001509017A (en)
AU (1) AU749606C (en)
CA (1) CA2278645A1 (en)
WO (1) WO1998032847A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7504493B2 (en) 1997-01-23 2009-03-17 The John Hopkins University Characterization of the yeast transcriptome
WO2000077214A2 (en) * 1999-06-16 2000-12-21 The John Hopkins University Characterization of the yeast transcriptome
FR2821087B1 (en) * 2001-02-16 2004-01-02 Centre Nat Rech Scient PROCESS FOR QUALITATIVE AND QUANTITATIVE ANALYSIS OF A POPULATION OF NUCLEIC ACIDS CONTAINED IN A SAMPLE
DE10160660A1 (en) 2001-12-11 2003-06-18 Bayer Cropscience Ag Polypeptides to identify fungicidally active compounds
US20060147926A1 (en) 2002-11-25 2006-07-06 Emmert-Buck Michael R Method and apparatus for performing multiple simultaneous manipulations of biomolecules in a two-dimensional array
JP5143552B2 (en) * 2004-07-23 2013-02-13 ジーイー・ヘルスケア・ユーケイ・リミテッド Cell cycle phase marker
JP2018531610A (en) * 2015-11-02 2018-11-01 オリジェン， インコーポレイテッド Cell cycle block improves the generation efficiency of induced pluripotent stem cells

Non-Patent Citations (17)

* Cited by examiner, † Cited by third party
Title
A. GOFFEAU ET AL.: "Life with 6000 genes", SCIENCE, vol. 274, 25 October 1996 (1996-10-25), AAAS,WASHINGTON,DC,US, pages 546 - 567, XP002070912 *
BISHOP D K ET AL: "DMC1: A MEIOSIS-SPECIFIC YEAST HOMOLOG OF E. COLI RECA REQUIRED FORRECOMBINATION, SYNAPTONEMAL COMPLEX FORMATION, AND CELL CYCLE PROGRESSION", CELL, vol. 69, 1 May 1992 (1992-05-01), pages 439 - 456, XP000676406 *
BURNS N ET AL: "LARGE-SCALE ANALYSIS OF GENE EXPRESSION, PROTEIN LOCALIZATION, AND GENE DISRUPTION IN SACCHAROMYCES CERECISIAE", GENES AND DEVELOPMENT, vol. 8, no. 9, 1 May 1994 (1994-05-01), pages 1087 - 1105, XP000569086 *
C. FRANKHAUSER ET AL.: "The S. pombe cdc15 gene is a key element in the reorganization of F-actin at mitose", CELL, vol. 82, 11 August 1995 (1995-08-11), CELL PRESS,CAMBRIDGE,MA,US;, pages 435 - 444, XP002070907 *
C. PRICE ET AL.: "A general approach to the isolation of cell cycle-regulated genes in the budding yeast, Saccharomyces cerevisiae", J. MOL. BIOL., vol. 218, no. 3, 5 April 1991 (1991-04-05), ACADEMIC PRESS,US, pages 543 - 556, XP002070908 *
J.H. TOYN ET AL.: "The cell-cycle-regulated yeast gene DBF2, encoding a putative protein kinase, has a homologue that is not under cell-cycle control", GENE, vol. 104, 1991, ELSEVIER SCIENCE PUBLISHERS,B.V.,AMSTERDAM,NL;, pages 63 - 70, XP002070905 *
K. NASMYTH: "Control of the yeast cell cycle by the Cdc28 protein kinase", CURRENT OPINION IN CELL BIOLOGY, vol. 5, no. 2, April 1993 (1993-04-01), CURRENT BIOLOGY, LTD., US, pages 166 - 179, XP002071095 *
LOCKHART D J ET AL: "EXPRESSION MONITORING BY HYBRIDIZATION TO HIGH-DENSITY OLIGONUCLEOTIDE ARRAYS", BIO/TECHNOLOGY, vol. 14, no. 13, December 1996 (1996-12-01), pages 1675 - 1680, XP002022521 *
M. SCHENA ET AL.: "Paralel human genome analysis: Microarray-based expression monitoring of 1000 genes", PROC. NATL. ACAD. SCI., vol. 93, October 1996 (1996-10-01), NATL. ACAD. SCI.,WASHINGTON,DC,US;, pages 10614 - 10619, XP002070911 *
R.M. GOLDSTEYN ET AL.: "Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5", J. CELL SCIENCE, vol. 107, no. 6, 1994, THE COMPANY OF BIOLOGISTS LIMITED, GB, pages 1509 - 1517, XP002070910 *
S.J. ELLEDGE AND R.W. DAVIS: "DNA damage induction of ribonucleotide reductase", MOL. CELL. BIOL., vol. 9, no. 11, November 1989 (1989-11-01), ASM WASHINGTON, DC,US, pages 4932 - 4940, XP002070906 *
SCHENA M ET AL: "QUANTITATIVE MONITORING OF GENE EXPRESSION PATTERNS WITH A COMPLEMENTARY DNA MICROARRAY", SCIENCE, vol. 270, no. 5235, 20 October 1995 (1995-10-20), pages 467 - 470, XP000644675 *
SHALON D ET AL: "A DNA MICROARRAY SYSTEM FOR ANALYZING COMPLEX DNA SAMPLES USING TWO-COLOR FLUORESCENT PROBE HYBRIDIZATION", GENOME RESEARCH, vol. 6, no. 7, 1 July 1996 (1996-07-01), pages 639 - 645, XP000597095 *
T. YASUGI AND P.M. HOWLEY: "Identification of the structural and functional human homolog of the yeast ubiquitin conjugated enzyme UBC9", NUCLEIC ACIDS RESEARCH, vol. 24, no. 11, 1996, IRL PRESS LIMITED,OXFORD,ENGLAND, pages 2005 - 2010, XP002070909 *
V.E.VCELCULESCU ET AL.: "Characterization of the yeast transcriptome", CELL, vol. 88, 24 January 1997 (1997-01-24), CELL PRESS,CAMBRIDGE,MA,US;, pages 243 - 251, XP002070903 *
VELCULESCU V E ET AL: "SERIAL ANALYSIS OF GENE EXPRESSION", SCIENCE, vol. 270, 20 October 1995 (1995-10-20), pages 484 - 487, XP002053721 *
Y. KYU JANG ET AL.: "Differential expression of the rhp51+ gene, a recA and RAD51 homolog from the fission yeast Schizosaccharomyces pombe", GENE, vol. 169, 1996, ELSEVIER SCIENCE PUBLISHERS,B.V.,AMSTERDAM,NL;, pages 125 - 130, XP002070904 *

Also Published As

Publication number Publication date
JP2001509017A (en) 2001-07-10
AU749606C (en) 2007-05-17
AU5928098A (en) 1998-08-18
EP0970202A2 (en) 2000-01-12
AU749606B2 (en) 2002-06-27
CA2278645A1 (en) 1998-07-30
WO1998032847A2 (en) 1998-07-30

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