[go: up one dir, main page]

WO1998017166A3 - Systeme d'imagerie confocale utilise dans l'examen des tissus dermiques - Google Patents

Systeme d'imagerie confocale utilise dans l'examen des tissus dermiques Download PDF

Info

Publication number
WO1998017166A3
WO1998017166A3 PCT/US1997/017990 US9717990W WO9817166A3 WO 1998017166 A3 WO1998017166 A3 WO 1998017166A3 US 9717990 W US9717990 W US 9717990W WO 9817166 A3 WO9817166 A3 WO 9817166A3
Authority
WO
WIPO (PCT)
Prior art keywords
confocal imaging
dermal tissue
head
confocal
platen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1997/017990
Other languages
English (en)
Other versions
WO1998017166B1 (fr
WO1998017166A2 (fr
Inventor
James M Zavislan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lucid Technologies Inc
Original Assignee
Lucid Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lucid Technologies Inc filed Critical Lucid Technologies Inc
Priority to EP97945515A priority Critical patent/EP1011441B1/fr
Priority to AU46696/97A priority patent/AU4669697A/en
Publication of WO1998017166A2 publication Critical patent/WO1998017166A2/fr
Publication of WO1998017166A3 publication Critical patent/WO1998017166A3/fr
Publication of WO1998017166B1 publication Critical patent/WO1998017166B1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/684Indicating the position of the sensor on the body
    • A61B5/6842Indicating the position of the sensor on the body by marking the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0068Confocal scanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/06Devices, other than using radiation, for detecting or locating foreign bodies ; Determining position of diagnostic devices within or on the body of the patient
    • A61B5/061Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/444Evaluating skin marks, e.g. mole, nevi, tumour, scar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/445Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683Means for maintaining contact with the body
    • A61B5/6834Means for maintaining contact with the body using vacuum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683Means for maintaining contact with the body
    • A61B5/6835Supports or holders, e.g., articulated arms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6843Monitoring or controlling sensor contact pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/70Means for positioning the patient in relation to the detecting, measuring or recording means
    • A61B5/704Tables

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Human Computer Interaction (AREA)
  • Surgical Instruments (AREA)
  • Microscoopes, Condenser (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Eye Examination Apparatus (AREA)
  • Laser Surgery Devices (AREA)

Abstract

L'invention porte sur un système amélioré d'imagerie confocale utilisé dans l'examen des tissus dermiques d'un patient, ce système minimisant l'instabilité des images confocales en réduisant le mouvement relatif du tissu par rapport à l'optique d'imagerie confocale du système. Ce système comprend un mécanisme visant à maintenir une zone du tissu dermique sous tension en appliquant une force sur le pourtour de la zone, et une tête d'imagerie couplée à ce mécanisme et permettant de représenter la peau sous tension. Le mécanisme comprend une structure mécanique telle qu'une plaque, une entretoise ou un dispositif de fixation qui supporte à la fois la tête du système d'imagerie et applique une tension sur une zone superficielle limitée du tissu de façon à minimiser le mouvement de la peau au cours de l'imagerie confocale.
PCT/US1997/017990 1996-10-18 1997-10-08 Systeme d'imagerie confocale utilise dans l'examen des tissus dermiques Ceased WO1998017166A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP97945515A EP1011441B1 (fr) 1996-10-18 1997-10-08 Systeme d'imagerie confocale utilise dans l'examen des tissus dermiques
AU46696/97A AU4669697A (en) 1996-10-18 1997-10-08 System for confocal imaging within dermal tissue

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2884796P 1996-10-18 1996-10-18
US60/028,847 1996-10-18

Publications (3)

Publication Number Publication Date
WO1998017166A2 WO1998017166A2 (fr) 1998-04-30
WO1998017166A3 true WO1998017166A3 (fr) 1998-08-06
WO1998017166B1 WO1998017166B1 (fr) 1998-10-01

Family

ID=21845806

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/017990 Ceased WO1998017166A2 (fr) 1996-10-18 1997-10-08 Systeme d'imagerie confocale utilise dans l'examen des tissus dermiques

Country Status (4)

Country Link
US (5) US6424852B1 (fr)
EP (1) EP1011441B1 (fr)
AU (1) AU4669697A (fr)
WO (1) WO1998017166A2 (fr)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010041843A1 (en) * 1999-02-02 2001-11-15 Mark Modell Spectral volume microprobe arrays
US6745067B1 (en) * 1998-09-14 2004-06-01 Lucid, Inc. System for marking the locations of imaged tissue with respect to the surface of the tissue
US6424852B1 (en) * 1996-10-18 2002-07-23 Lucid, Inc. System for confocal imaging within dermal tissue
US8182473B2 (en) 1999-01-08 2012-05-22 Palomar Medical Technologies Cooling system for a photocosmetic device
US6517532B1 (en) 1997-05-15 2003-02-11 Palomar Medical Technologies, Inc. Light energy delivery head
US7204832B2 (en) 1996-12-02 2007-04-17 Pálomar Medical Technologies, Inc. Cooling system for a photo cosmetic device
ATE409005T1 (de) 1997-03-19 2008-10-15 Lucid Inc Zellchirurgie unter benutzung konfokaler mikroskopie
EP0991372B1 (fr) 1997-05-15 2004-08-04 Palomar Medical Technologies, Inc. Appareil de traitement dermatologique
WO1999046005A1 (fr) 1998-03-12 1999-09-16 Palomar Medical Technologies, Inc. Systeme d'application de rayonnement electromagnetique sur la peau
AU5923299A (en) 1998-09-14 2000-04-03 Lucid, Inc. A system for marking the locations of imaged tissue with respect to the surface of the tissue
JP2002532181A (ja) 1998-12-23 2002-10-02 メディスペクトラ, インコーポレイテッド 頚部のスクリーニングのための光学的方法およびシステム
US7260248B2 (en) 1999-12-15 2007-08-21 Medispectra, Inc. Image processing using measures of similarity
US7187810B2 (en) 1999-12-15 2007-03-06 Medispectra, Inc. Methods and systems for correcting image misalignment
US6530882B1 (en) * 2000-06-30 2003-03-11 Inner Vision Imaging, L.L.C. Endoscope having microscopic and macroscopic magnification
US6888319B2 (en) 2001-03-01 2005-05-03 Palomar Medical Technologies, Inc. Flashlamp drive circuit
AU2002367397A1 (en) 2001-12-27 2003-07-24 Palomar Medical Technologies, Inc. Method and apparatus for improved vascular related treatment
US20040133112A1 (en) * 2002-03-08 2004-07-08 Milind Rajadhyaksha System and method for macroscopic and confocal imaging of tissue
EP1523283A1 (fr) 2002-06-19 2005-04-20 Palomar Medical Technologies, Inc. Methode et appareil de traitement photothermique d'un tissu en profondeur
AU2003245573A1 (en) 2002-06-19 2004-01-06 Palomar Medical Technologies, Inc. Method and apparatus for treatment of cutaneous and subcutaneous conditions
US7459696B2 (en) * 2003-04-18 2008-12-02 Schomacker Kevin T Methods and apparatus for calibrating spectral data
US7469160B2 (en) 2003-04-18 2008-12-23 Banks Perry S Methods and apparatus for evaluating image focus
US7309867B2 (en) * 2003-04-18 2007-12-18 Medispectra, Inc. Methods and apparatus for characterization of tissue samples
US7282723B2 (en) 2002-07-09 2007-10-16 Medispectra, Inc. Methods and apparatus for processing spectral data for use in tissue characterization
US7136518B2 (en) 2003-04-18 2006-11-14 Medispectra, Inc. Methods and apparatus for displaying diagnostic data
US6768918B2 (en) 2002-07-10 2004-07-27 Medispectra, Inc. Fluorescent fiberoptic probe for tissue health discrimination and method of use thereof
JP4790268B2 (ja) 2002-10-23 2011-10-12 パロマー・メディカル・テクノロジーズ・インコーポレイテッド 冷却剤及び局所物質と共に使用する光処理装置
US7149566B2 (en) 2002-10-31 2006-12-12 Manoa Medical, Inc. Soft tissue orientation and imaging guide systems and methods
FR2858206B1 (fr) * 2003-07-28 2006-04-14 Fabre Pierre Dermo Cosmetique Extensiometre de la peau
US7220254B2 (en) 2003-12-31 2007-05-22 Palomar Medical Technologies, Inc. Dermatological treatment with visualization
US20050177919A1 (en) * 2004-02-04 2005-08-18 Igal Kushnir Medical garment
ES2611284T3 (es) 2004-04-01 2017-05-08 The General Hospital Corporation Aparato para tratamiento cutáneo y remodelación de tejido
US20050280892A1 (en) * 2004-05-28 2005-12-22 Nobuyuki Nagasawa Examination method and examination apparatus
US7809618B2 (en) * 2004-09-28 2010-10-05 Diane Velona Educational tuition securities system
US20060100523A1 (en) * 2004-11-08 2006-05-11 Ogle John S Noninvasive blood vessel location device and method
DE102005043573A1 (de) * 2005-04-07 2006-10-12 Universität Duisburg-Essen Vorrichtung und Verfahren zur optischen Untersuchung des menschlichen oder tierischen Körpers
US7856985B2 (en) 2005-04-22 2010-12-28 Cynosure, Inc. Method of treatment body tissue using a non-uniform laser beam
WO2007035444A2 (fr) 2005-09-15 2007-03-29 Palomar Medical Technologies, Inc. Dispositif de caractérisation optique de la peau
US7864996B2 (en) * 2006-02-17 2011-01-04 Lucid, Inc. System for macroscopic and confocal imaging of tissue
JP2007279387A (ja) * 2006-04-06 2007-10-25 Olympus Corp 生体観察用スタビライザ
US8260401B2 (en) * 2006-07-26 2012-09-04 University Of Rochester Non-invasive in-vivo imaging of mechanoreceptors in skin using confocal microscopy
US7586957B2 (en) 2006-08-02 2009-09-08 Cynosure, Inc Picosecond laser apparatus and methods for its operation and use
US7973925B2 (en) * 2007-02-06 2011-07-05 C8 Medisensors Inc. Apparatus for stabilizing mechanical, thermal, and optical properties and for reducing the fluorescence of biological samples for optical evaluation
JP5643101B2 (ja) 2007-10-25 2014-12-17 ワシントン・ユニバーシティWashington University 散乱媒体の画像化方法、画像化装置及び画像化システム
EP2324362B1 (fr) 2008-08-04 2017-12-13 University of Utah Research Foundation Application de colorant pour une imagerie homofocale de microstructure cellulaire
US20100087806A1 (en) * 2008-10-07 2010-04-08 Vandolay, Inc. Automated Cryogenic Skin Treatment
US9528966B2 (en) * 2008-10-23 2016-12-27 Washington University Reflection-mode photoacoustic tomography using a flexibly-supported cantilever beam
US9351705B2 (en) 2009-01-09 2016-05-31 Washington University Miniaturized photoacoustic imaging apparatus including a rotatable reflector
US9919168B2 (en) 2009-07-23 2018-03-20 Palomar Medical Technologies, Inc. Method for improvement of cellulite appearance
US9086365B2 (en) 2010-04-09 2015-07-21 Lihong Wang Quantification of optical absorption coefficients using acoustic spectra in photoacoustic tomography
US9795340B2 (en) * 2010-12-13 2017-10-24 National Taiwan University Vacuum-pump sucker
US8997572B2 (en) 2011-02-11 2015-04-07 Washington University Multi-focus optical-resolution photoacoustic microscopy with ultrasonic array detection
US9031701B2 (en) 2011-02-15 2015-05-12 Hemosonics Llc Characterization of blood hemostasis and oxygen transport parameters
US8411265B2 (en) 2011-06-14 2013-04-02 C8 Medisensors Inc. Apparatus for stabilizing mechanical, thermal, and optical properties and for reducing the fluorescence of biological samples for optical evaluation
CN104254767B (zh) 2012-02-26 2016-10-26 克力博成像诊断股份有限公司 用于光学切片显微镜的组织样本工作台
EP2839552A4 (fr) 2012-04-18 2015-12-30 Cynosure Inc Appareil à laser picoseconde et procédé de traitement de tissus cibles à l'aide de celui-ci
EP2711758A1 (fr) * 2012-09-21 2014-03-26 Mavig GmbH Chapeau de repérage pour microscope à foyer commun
WO2014063005A1 (fr) 2012-10-18 2014-04-24 Washington University Imagerie du cerveau par tomographie photoacoustique/thermoacoustique transcrânienne renseignée par des données d'images complémentaires
EP2929327B1 (fr) 2012-12-05 2019-08-14 Perimeter Medical Imaging, Inc. Système et procédé pour une imagerie oct grand angle
WO2014145707A2 (fr) 2013-03-15 2014-09-18 Cynosure, Inc. Systèmes de rayonnement optique picoseconde et procédés d'utilisation
WO2015077355A1 (fr) 2013-11-19 2015-05-28 Washington University Systèmes et procédés de microscopie photo-acoustique de relaxation de grueneisen et mise en forme du front d'onde photo-acoustique
EP4035595B1 (fr) 2014-05-05 2025-09-17 Caliber Imaging & Diagnostics Inc. Procédé de mise en correspondance des emplacements d'images confocales capturées d'une lésion dans les tissus de la peau
US9726647B2 (en) 2015-03-17 2017-08-08 Hemosonics, Llc Determining mechanical properties via ultrasound-induced resonance
US10088427B2 (en) 2015-03-31 2018-10-02 Samantree Medical Sa Systems and methods for in-operating-theatre imaging of fresh tissue resected during surgery for pathology assessment
US10568695B2 (en) * 2016-09-26 2020-02-25 International Business Machines Corporation Surgical skin lesion removal
US11672426B2 (en) 2017-05-10 2023-06-13 California Institute Of Technology Snapshot photoacoustic photography using an ergodic relay
WO2019014767A1 (fr) 2017-07-18 2019-01-24 Perimeter Medical Imaging, Inc. Récipient d'échantillon pour stabiliser et aligner des échantillons de tissu biologique excisés pour analyse ex vivo
US10539776B2 (en) 2017-10-31 2020-01-21 Samantree Medical Sa Imaging systems with micro optical element arrays and methods of specimen imaging
US11747603B2 (en) 2017-10-31 2023-09-05 Samantree Medical Sa Imaging systems with micro optical element arrays and methods of specimen imaging
US10928621B2 (en) 2017-10-31 2021-02-23 Samantree Medical Sa Sample dishes for use in microscopy and methods of their use
CN112042066A (zh) 2018-02-26 2020-12-04 赛诺秀股份有限公司 调q倾腔亚纳秒激光器
US11530979B2 (en) 2018-08-14 2022-12-20 California Institute Of Technology Multifocal photoacoustic microscopy through an ergodic relay
WO2020051246A1 (fr) 2018-09-04 2020-03-12 California Institute Of Technology Microscopie et spectroscopie photo-acoustique infrarouge à résolution améliorée
US11369280B2 (en) 2019-03-01 2022-06-28 California Institute Of Technology Velocity-matched ultrasonic tagging in photoacoustic flowgraphy
WO2021092250A1 (fr) 2019-11-05 2021-05-14 California Institute Of Technology Anti-repliement spatiotemporel en tomographie photoacoustique assistée par ordinateur
US11636591B2 (en) 2020-06-18 2023-04-25 Alibaba Group Holding Limited Surface imaging using high incident angle of light rays

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5146923A (en) * 1986-12-18 1992-09-15 Dhawan Atam P Apparatus and method for skin lesion examination

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281645A (en) * 1977-06-28 1981-08-04 Duke University, Inc. Method and apparatus for monitoring metabolism in body organs
US4170987A (en) * 1977-11-28 1979-10-16 California Institute Of Technology Medical diagnosis system and method with multispectral imaging
US4515165A (en) * 1980-02-04 1985-05-07 Energy Conversion Devices, Inc. Apparatus and method for detecting tumors
US4385634A (en) 1981-04-24 1983-05-31 University Of Arizona Foundation Radiation-induced thermoacoustic imaging
US4442844A (en) 1981-08-28 1984-04-17 Navach Joseph H Method and apparatus for making physiological measurements
DE3231483A1 (de) 1982-08-25 1984-03-01 Albert Prof. Dr. 3550 Marburg Huch Anordnung zur vermessung von oberflaechenkapillaren
US5139025A (en) * 1983-10-14 1992-08-18 Somanetics Corporation Method and apparatus for in vivo optical spectroscopic examination
US4570638A (en) * 1983-10-14 1986-02-18 Somanetics Corporation Method and apparatus for spectral transmissibility examination and analysis
US4807979A (en) * 1986-01-24 1989-02-28 Geno Saccomanno Microscope slide marking device
CH669325A5 (fr) 1987-01-22 1989-03-15 Newer Sa
EP0393165B2 (fr) 1988-07-13 2007-07-25 Optiscan Pty Ltd Endoscope a balayage a foyer commun
US5016173A (en) * 1989-04-13 1991-05-14 Vanguard Imaging Ltd. Apparatus and method for monitoring visually accessible surfaces of the body
US5195522A (en) * 1990-11-30 1993-03-23 Ivac Corporation Tonometry sensor calibration apparatus
US5719700A (en) 1991-10-11 1998-02-17 L'oreal Apparatus for in vivo observation of the microscopic structure of the skin or of a similar tissue
US5371368A (en) * 1992-07-23 1994-12-06 Alfano; Robert R. Ultrafast optical imaging of objects in a scattering medium
US5860934A (en) * 1992-12-21 1999-01-19 Artann Corporation Method and device for mechanical imaging of breast
US5524636A (en) 1992-12-21 1996-06-11 Artann Corporation Dba Artann Laboratories Method and apparatus for elasticity imaging
US5860967A (en) * 1993-07-21 1999-01-19 Lucid, Inc. Dermatological laser treatment system with electronic visualization of the area being treated
DE4340072C2 (de) * 1993-11-24 1996-05-15 Siemens Ag Vorrichtung zur Untersuchung von Gewebe mit Licht
JP2605584Y2 (ja) * 1993-12-07 2000-07-24 日本光電工業株式会社 マルチセンサ
FR2719058B1 (fr) * 1994-04-22 1996-07-12 Superba Sa Machine pour teindre en continu des fils textiles.
US5598269A (en) * 1994-05-12 1997-01-28 Children's Hospital Medical Center Laser guided alignment apparatus for medical procedures
JP3364323B2 (ja) 1994-05-17 2003-01-08 謙 石原 非侵襲血液分析装置
US5730133A (en) * 1994-05-20 1998-03-24 Dynamics Imaging, Inc. Optical functional mamoscope
JPH07333517A (ja) * 1994-06-07 1995-12-22 Sumitomo Electric Ind Ltd ステ−ジ座標記録機構を有する顕微鏡システム
US5701902A (en) * 1994-09-14 1997-12-30 Cedars-Sinai Medical Center Spectroscopic burn injury evaluation apparatus and method
JP3562847B2 (ja) 1994-11-15 2004-09-08 謙 石原 ヘモグロビン濃度測定装置
AT403654B (de) * 1994-12-01 1998-04-27 Binder Michael Dr Einrichtung zur optischen untersuchung von human-haut sowie derselben zugeordnete auswertungs-einrichtung
US5848177A (en) * 1994-12-29 1998-12-08 Board Of Trustees Operating Michigan State University Method and system for detection of biological materials using fractal dimensions
WO1996021938A1 (fr) 1995-01-13 1996-07-18 The General Hospital Corporation Microscope a laser de balayage a foyer commun a vitesse video
US5880880A (en) 1995-01-13 1999-03-09 The General Hospital Corp. Three-dimensional scanning confocal laser microscope
US5557452A (en) 1995-02-06 1996-09-17 University Of Hawaii Confocal microscope system
JPH08299310A (ja) * 1995-05-02 1996-11-19 Toa Medical Electronics Co Ltd 非侵襲血液分析装置およびその方法
US5999836A (en) 1995-06-06 1999-12-07 Nelson; Robert S. Enhanced high resolution breast imaging device and method utilizing non-ionizing radiation of narrow spectral bandwidth
US5788639A (en) 1995-07-13 1998-08-04 Lucid Technologies, Inc. Confocal imaging through thick dermal tissue
US6263233B1 (en) 1995-07-13 2001-07-17 Lucid, Inc. Handheld imaging microscope
AP931A (en) * 1995-10-23 2001-02-02 Cytometrics Inc Method and apparatus for reflected imaging analysis.
US5833634A (en) * 1995-11-09 1998-11-10 Uromed Corporation Tissue examination
US5606971A (en) 1995-11-13 1997-03-04 Artann Corporation, A Nj Corp. Method and device for shear wave elasticity imaging
US5840023A (en) 1996-01-31 1998-11-24 Oraevsky; Alexander A. Optoacoustic imaging for medical diagnosis
US5842995A (en) * 1996-06-28 1998-12-01 Board Of Regents, The Univerisity Of Texas System Spectroscopic probe for in vivo measurement of raman signals
US5851181A (en) * 1996-08-30 1998-12-22 Esc Medical Systems Ltd. Apparatus for simultaneously viewing and spectrally analyzing a portion of skin
US6745067B1 (en) 1998-09-14 2004-06-01 Lucid, Inc. System for marking the locations of imaged tissue with respect to the surface of the tissue
US6424852B1 (en) 1996-10-18 2002-07-23 Lucid, Inc. System for confocal imaging within dermal tissue
EP1011446A1 (fr) * 1997-02-28 2000-06-28 Electro-Optical Sciences, Inc. Systemes et procedes d'imagerie multispectrale et de caracterisation d'un tissu cutane
ATE227338T1 (de) 1998-03-18 2002-11-15 Massachusetts Inst Technology Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane
US6993167B1 (en) * 1999-11-12 2006-01-31 Polartechnics Limited System and method for examining, recording and analyzing dermatological conditions
US6509161B1 (en) 2000-02-29 2003-01-21 Gentronix Limited Green fluorescent protein

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5146923A (en) * 1986-12-18 1992-09-15 Dhawan Atam P Apparatus and method for skin lesion examination

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1011441A4 *

Also Published As

Publication number Publication date
WO1998017166B1 (fr) 1998-10-01
US8606343B2 (en) 2013-12-10
EP1011441A2 (fr) 2000-06-28
US20020151782A1 (en) 2002-10-17
AU4669697A (en) 1998-05-15
US20070287921A1 (en) 2007-12-13
US20050171441A1 (en) 2005-08-04
US7225010B1 (en) 2007-05-29
US6937886B2 (en) 2005-08-30
EP1011441B1 (fr) 2011-07-20
US8121670B2 (en) 2012-02-21
WO1998017166A2 (fr) 1998-04-30
US6424852B1 (en) 2002-07-23
EP1011441A4 (fr) 2000-06-28

Similar Documents

Publication Publication Date Title
WO1998017166A3 (fr) Systeme d'imagerie confocale utilise dans l'examen des tissus dermiques
AU4056895A (en) Medical devices
US4964710B1 (en) Disposable rigid endoscope
WO2001085086A3 (fr) Systeme de propulsion a moteur pour lit
ES2176572T3 (es) Aparato para la derivacion de potenciales cerebrales evocados acusticamente.
USD439337S1 (en) Surgical needle holder
EP0761171A3 (fr)
CA2230615A1 (fr) Systeme d'empreinte pour extremite d'implant emergeant d'une structure tissulaire humaine
CA2132277A1 (fr) Dispositif d'injection
AU5050593A (en) Surgical cutting instrument for coring tissue affixed thereto
AU3552895A (en) Position tracking and imaging system for use in medical applications using a reference unit secured to a patient's head
AU5003990A (en) Method and device for the controlled local, non-invasive application of dc pulses to human tissues
AU3531289A (en) Heart monitor for acquiring three simultaneous leads
AU1418492A (en) Surgical probe for constrained distal energy application
WO2000007537A3 (fr) Civière ob/gyn
CA2095655A1 (fr) Appareil de section endoscopique
ITMI922308A1 (it) Apparecchiatura per tingere tessuti campionati da un corpo vivente al fine di osservare l'immunoreazione dei tessuti.
AU6843687A (en) Catheter with high speed moving working head for in-body surgical procedures
AU3455393A (en) Preparation for skin use
AU1549395A (en) A device for passive-motion treatment of the human body
IN171755B (fr)
EP1020192A3 (fr) Composition anti-cellulitique
GB2198948B (en) Endoscope body cavity pressure adjusting system
ITUD960088A0 (it) Apparato per l'ottenimento di informazioni bioelettriche dal corpo umano
AU2990692A (en) Diagnostic method for pompe's disease

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW AM AZ BY KG KZ MD RU TJ TM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH KE LS MW SD SZ UG ZW AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 1997945515

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

NENP Non-entry into the national phase

Ref country code: CA

WWP Wipo information: published in national office

Ref document number: 1997945515

Country of ref document: EP