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WO1998002240B1 - Preservation par formation de mousse - Google Patents

Preservation par formation de mousse

Info

Publication number
WO1998002240B1
WO1998002240B1 PCT/US1997/012156 US9712156W WO9802240B1 WO 1998002240 B1 WO1998002240 B1 WO 1998002240B1 US 9712156 W US9712156 W US 9712156W WO 9802240 B1 WO9802240 B1 WO 9802240B1
Authority
WO
WIPO (PCT)
Prior art keywords
foam
dispersion
solution
temperature
suspension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1997/012156
Other languages
English (en)
Other versions
WO1998002240A1 (fr
Filing date
Publication date
Priority claimed from US08/785,473 external-priority patent/US5766520A/en
Priority to AU36606/97A priority Critical patent/AU714328B2/en
Application filed filed Critical
Priority to IL12797197A priority patent/IL127971A/en
Priority to DE0914202T priority patent/DE914202T1/de
Priority to JP10506201A priority patent/JP2000515856A/ja
Priority to HU9903917A priority patent/HUP9903917A3/hu
Priority to EP97933415A priority patent/EP0914202A4/fr
Priority to BR9711808-7A priority patent/BR9711808A/pt
Priority to EA199900268A priority patent/EA001138B1/ru
Priority to NZ333738A priority patent/NZ333738A/xx
Publication of WO1998002240A1 publication Critical patent/WO1998002240A1/fr
Publication of WO1998002240B1 publication Critical patent/WO1998002240B1/fr
Priority to NO990158A priority patent/NO990158D0/no
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Abstract

L'invention concerne un procédé permettant de préserver des dispersions biologiques, des suspensions, des émulsions et des solutions sensibles par la formation de mousses stables à partir de matériaux fluides destinés à être déshydratés, utile en tant qu'aide au séchage d'un ou de plusieurs substrats biologiquement actifs dans le fluide, et à la préparation d'un produit séché facilement divisible, approprié à un usage commercial postérieur. On forme les mousses stables par élimination partielle d'eau afin d'obtenir un liquide visqueux, et en soumettant ensuite ce liquide réduit à un vide pour provoquer une ébullition au cours d'un séchage ultérieur, à des températures sensiblement inférieures à 100 °C. En d'autres termes, on applique une pression réduite à des solutions visqueuses ou des suspensions de matériaux biologiquement actifs pour provoquer la formation de mousse au cours de l'ébullition de celles-ci, et, au cours de cette formation de mousse, une élimination additionnelle de solvant provoque la production ultime d'une mousse stable à alvéoles ouverts ou fermés.
PCT/US1997/012156 1996-07-15 1997-07-14 Preservation par formation de mousse Ceased WO1998002240A1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
BR9711808-7A BR9711808A (pt) 1996-07-15 1997-07-14 Preservação através de formação de espuma.
EP97933415A EP0914202A4 (fr) 1996-07-15 1997-07-14 Preservation par formation de mousse
IL12797197A IL127971A (en) 1996-07-15 1997-07-14 Preservation by creating foam
DE0914202T DE914202T1 (de) 1996-07-15 1997-07-14 Konservierung durch schaumformung
JP10506201A JP2000515856A (ja) 1996-07-15 1997-07-14 泡沫形成による保存
HU9903917A HUP9903917A3 (en) 1996-07-15 1997-07-14 Preservation by foam formation
EA199900268A EA001138B1 (ru) 1996-07-15 1997-07-14 Защита пенообразованием
AU36606/97A AU714328B2 (en) 1996-07-15 1997-07-14 Preservation by foam formation
NZ333738A NZ333738A (en) 1996-07-15 1997-07-14 Shelf preservation of biological active material by forming a mechanically stable foam thereof
NO990158A NO990158D0 (no) 1996-07-15 1999-01-14 Konservering ved skumdannelse

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2179696P 1996-07-15 1996-07-15
US08/785,473 US5766520A (en) 1996-07-15 1997-01-17 Preservation by foam formation
US60/021,796 1997-01-17
US08/785,473 1997-01-17

Publications (2)

Publication Number Publication Date
WO1998002240A1 WO1998002240A1 (fr) 1998-01-22
WO1998002240B1 true WO1998002240B1 (fr) 1998-03-05

Family

ID=26695104

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/012156 Ceased WO1998002240A1 (fr) 1996-07-15 1997-07-14 Preservation par formation de mousse

Country Status (18)

Country Link
US (1) US5766520A (fr)
EP (1) EP0914202A4 (fr)
JP (1) JP2000515856A (fr)
KR (1) KR100457748B1 (fr)
CN (1) CN1116104C (fr)
AU (1) AU714328B2 (fr)
BR (1) BR9711808A (fr)
CA (1) CA2260233A1 (fr)
CZ (1) CZ7999A3 (fr)
DE (1) DE914202T1 (fr)
EA (1) EA001138B1 (fr)
HU (1) HUP9903917A3 (fr)
IL (1) IL127971A (fr)
NO (1) NO990158D0 (fr)
NZ (1) NZ333738A (fr)
PL (1) PL331174A1 (fr)
TR (1) TR199900127T2 (fr)
WO (1) WO1998002240A1 (fr)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679088B1 (fr) * 1992-09-29 2002-07-10 Inhale Therapeutic Systems Liberation dans les poumons de fragments actifs d'hormone parathyroidienne
US20030113273A1 (en) * 1996-06-17 2003-06-19 Patton John S. Methods and compositions for pulmonary delivery of insulin
DE69535897D1 (de) 1994-03-07 2009-01-22 Nektar Therapeutics Verfahren und Zusammensetzung für die pulmonale Darreichung von Insulin
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
AU3570495A (en) 1994-09-22 1996-04-09 Quadrant Holdings Cambridge Limited Compositions for use in rehydration and nutrition during athletic exercise and methods of making same
US6964771B1 (en) 1995-06-07 2005-11-15 Elan Drug Delivery Limited Method for stably incorporating substances within dry, foamed glass matrices
US6509146B1 (en) 1996-05-29 2003-01-21 Universal Preservation Technologies, Inc. Scalable long-term shelf preservation of sensitive biological solutions and suspensions
US6468782B1 (en) * 1996-12-05 2002-10-22 Quadrant Healthcare (Uk) Limited Methods of preserving prokaryotic cells and compositions obtained thereby
GB9705588D0 (en) 1997-03-18 1997-05-07 Anglia Research Foundation Stable particle in liquid formulations
US8563522B2 (en) * 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
US20020035071A1 (en) * 1997-07-08 2002-03-21 Josef Pitha Mimicking the metabolic effects of caloric restriction by administration of glucose antimetabolites
US20060116330A1 (en) * 1997-07-08 2006-06-01 The Iams Company Methods of mimicking the metabolic effects of caloric restriction by administration of mannoheptulose
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
JP2001524306A (ja) * 1997-11-26 2001-12-04 ユニバーサル プリザーベーション テクノロジーズ インコーポレイテッド ガラス化による不安定な生物学的サンプルの保存
US6306345B1 (en) 1998-05-06 2001-10-23 Universal Preservation Technologies, Inc. Industrial scale barrier technology for preservation of sensitive biological materials at ambient temperatures
US6214054B1 (en) 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
CA2360112A1 (fr) 1999-01-05 2000-07-13 Victor Bronshtein Systeme de commande de vide pour appareil de sechage de mousse
DK1175486T3 (da) * 1999-05-04 2007-10-29 Anhydro Ltd Fremgangsmåde til konservering af virus og mycoplasma
US6692695B1 (en) 1999-05-06 2004-02-17 Quadrant Drug Delivery Limited Industrial scale barrier technology for preservation of sensitive biological materials
WO2001012779A1 (fr) * 1999-08-19 2001-02-22 Universal Preservation Technologies, Inc. Conservation de cellules bacteriennes a temperature ambiante
WO2001037804A2 (fr) * 1999-11-22 2001-05-31 Universal Preservation Technologies, Inc. Conservation et preparation de matieres bioactives destinees au stockage et a l'administration dans des excipients hydrophobes
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7442388B2 (en) 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
AU2000264912A1 (en) 2000-06-07 2001-12-17 Universal Preservation Technologies, Inc. Industrial scale barrier technology for preservation of sensitive biological materials
JP4149803B2 (ja) * 2000-06-27 2008-09-17 エフ．ホフマン−ラ ロシュ アーゲー 組成物の調製方法
US6537666B1 (en) * 2000-10-23 2003-03-25 Universal Preservation Technologies, Inc. Methods of forming a humidity barrier for the ambient temperature preservation of sensitive biologicals
US6872357B1 (en) * 2000-11-22 2005-03-29 Quadrant Drug Delivery Limited Formulation of preservation mixtures containing sensitive biologicals to be stabilized for ambient temperature storage by drying
US7153472B1 (en) * 2000-11-22 2006-12-26 Quadrant Drug Delivery Limited Preservation and formulation of bioactive materials for storage and delivery in hydrophobic carriers
AU2002305461A1 (en) * 2001-05-07 2002-11-18 Universal Preservation Technologies, Inc. Preservation of competent cells at ambient temperatures
US6884866B2 (en) * 2001-10-19 2005-04-26 Avant Immunotherapeutics, Inc. Bulk drying and the effects of inducing bubble nucleation
MXPA04005865A (es) 2001-12-19 2004-09-13 Nektar Therapeutics Suministro de aminoglucosidos a los pulmones.
US6878168B2 (en) 2002-01-03 2005-04-12 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
AU2003247337B2 (en) * 2002-04-11 2007-09-06 Medimmune, Llc Preservation of bioactive materials by freeze dried foam
KR101130948B1 (ko) 2002-11-01 2012-03-30 글락소스미스클라인 바이오로지칼즈 에스.에이. 건조 공정
US20050100559A1 (en) * 2003-11-07 2005-05-12 The Procter & Gamble Company Stabilized compositions comprising a probiotic
US20050100636A1 (en) * 2003-11-10 2005-05-12 Megan Botteri [A Low-Calorie Sports Drink For Physically Active Women That is Fortified with Iron, Calcium and Essential Vitamins for Use in Rehydration and Replacing Electrolytes Lost During Periods of Physical Activity]
US20050152884A1 (en) 2003-12-19 2005-07-14 The Procter & Gamble Company Canine probiotic Bifidobacteria globosum
US20050158294A1 (en) * 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US8877178B2 (en) * 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US8894991B2 (en) * 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
US9744227B2 (en) 2004-06-02 2017-08-29 Universal Stabilization Technologies, Inc. Compositions containing ambient-temperature stable, inactivated but therapeutically active biopharmaceuticals and methods for formulation thereof
CA2569276C (fr) * 2004-06-02 2018-01-23 Victor Bronshtein Conservation par vaporisation
JP2007277094A (ja) * 2004-06-29 2007-10-25 Chemo Sero Therapeut Res Inst 改変ダニ主要アレルゲン含有医薬組成物
EP1771503B1 (fr) * 2004-07-30 2014-09-03 Enwave Corporation Procede permettant de produire des mousses hydrocolloides
EP1880001B1 (fr) * 2005-05-31 2011-06-08 The Iams Company Lactobacilli felins à activité probiotique
AU2006253007B2 (en) * 2005-05-31 2012-12-20 Alimentary Health Ltd Feline probiotic Bifidobacteria
US8968721B2 (en) 2005-12-28 2015-03-03 Advanced Bionutrition Corporation Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same
WO2007079147A2 (fr) 2005-12-28 2007-07-12 Advanced Bionutrition Corporation Véhicule de délivrance pour bactéries probiotiques, comprenant une matrice sèche en polysaccharides, saccharides et polyols sous forme de verre, et son procédé de préparation
US9453675B2 (en) * 2006-02-10 2016-09-27 Sp Industries, Inc. Method of inducing nucleation of a material
US8007992B2 (en) * 2006-10-27 2011-08-30 Edwards Lifesciences Corporation Method of treating glutaraldehyde-fixed pericardial tissue with a non-aqueous mixture of glycerol and a C1-C3 alcohol
WO2008076975A1 (fr) 2006-12-18 2008-06-26 Advanced Bionutrition Corporation Produit alimentaire sec contenant un probiotique vivant
EP2124966B1 (fr) 2007-02-01 2015-09-09 IAMS Europe B.V. Procédé pour réduire l'inflammation et le stress chez un mammifère en utilisant de glucose, d'avocat ou d'extraits d'avocat
KR101557169B1 (ko) * 2007-05-18 2015-10-02 메디뮨 엘엘씨 냉동 건조 발포체에 의한 생활성 물질의 보존
US9101691B2 (en) * 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
MX2010001054A (es) 2007-07-26 2010-04-21 Sanofi Pasteur Ltd Composiciones adyuvantes antigenicas y metodos.
CA2699120C (fr) * 2007-09-13 2014-07-08 Enwave Corporation Appareil et procede pour deshydrater des matieres biologiques
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
CA2736317C (fr) 2008-09-12 2015-06-16 Enwave Corporation Appareil et procede de deshydratation de matieres biologiques par congelation et micro-ondes
CA2756883C (fr) 2009-03-27 2018-01-09 Advanced Bionutrition Corp. Vaccins microparticulaires utilisables pour proceder a une vaccination et a des rappels par voie orale ou nasale chez les animaux, dont les poissons
JP5841527B2 (ja) 2009-05-26 2016-01-13 アドバンスド バイオニュートリション コーポレーション 生物学的に活性な微生物および／または生物活性材料を含む安定な乾燥粉末組成物およびその製造方法
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
EP2475393A4 (fr) * 2009-09-14 2013-08-21 Vu Truong-Le Formulation pour la stabilisation à température ambiante d'un vaccin bactérien atténué vivant
AR080073A1 (es) 2010-01-28 2012-03-14 Advanced Bionutrition Corp Composicion vitrea seca que comprende un material bioactivo
US9504750B2 (en) 2010-01-28 2016-11-29 Advanced Bionutrition Corporation Stabilizing composition for biological materials
NZ602707A (en) 2010-03-23 2014-05-30 Edwards Lifesciences Corp Methods of conditioning sheet bioprosthetic tissue
CN102946916B (zh) 2010-06-17 2015-03-18 爱德华兹生命科学公司 通过化学修饰抗原性碳水化合物稳定生物假体组织的方法
US8906601B2 (en) 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
SG187250A1 (en) * 2010-08-13 2013-03-28 Advanced Bionutrition Corp Dry storage stabilizing composition for biological materials
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
ES2856187T3 (es) 2013-05-31 2021-09-27 Victor Bronshtein Composiciones poliméricas que contienen productos biofarmacéuticos estables a temperatura ambiente y métodos para la formulación de las mismas
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
US9938558B2 (en) 2015-06-25 2018-04-10 Ascus Biosciences, Inc. Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
CA2989889A1 (fr) 2015-06-25 2016-12-29 Ascus Biosciences, Inc. Procedes, appareils et systemes pour analyser des souches de micro-organismes de communautes heterogenes complexes, predire et identifier des relations et des interactions fonctionnelles correspondantes et selectionner et synthetiser des ensembles microbiens bases sur ceux-ci
US10851399B2 (en) 2015-06-25 2020-12-01 Native Microbials, Inc. Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
US10953050B2 (en) 2015-07-29 2021-03-23 Advanced Bionutrition Corp. Stable dry probiotic compositions for special dietary uses
BR112018071198A2 (pt) 2016-04-15 2019-04-24 Ascus Biosciences, Inc. métodos para melhorar a produção agrícola de aves pela administração de consórcios microbianos ou de cepas purificadas dos mesmos
CN106434840B (zh) * 2016-12-02 2019-08-09 北京中检葆泰生物技术有限公司 一种用于微生物法定量检测维生素b12的微孔板、其试剂盒及其制备方法
IL267644B2 (en) 2016-12-28 2025-10-01 Native Microbials Inc Methods, devices and systems for the analysis of complex and mixed microorganism populations with sequential analytics, determination of their functional relationships and interactions and synthesis of microbial compositions including doses of microbial compositions and immune microbial compositions
JP2020504620A (ja) 2016-12-28 2020-02-13 アスカス バイオサイエンシーズ， インコーポレイテッド 複雑な不均一コミュニティの完全微生物株の解析、その機能的関連性及び相互作用の決定、ならびにそれに基づく生物反応性の改変剤の同定及び合成、のための方法、装置、及びシステム
CN106676160B (zh) * 2017-01-03 2020-02-21 北京中检葆泰生物技术有限公司 一种用于微生物法定量检测泛酸的微孔板、其试剂盒及其制备方法
CN106591415B (zh) * 2017-01-03 2019-12-10 北京中检葆泰生物技术有限公司 一种用于微生物法定量检测生物素的微孔板、其试剂盒及其制备方法
CN106701887B (zh) * 2017-01-03 2020-01-17 北京中检葆泰生物技术有限公司 一种用于微生物法定量检测叶酸的微孔板、其试剂盒及其制备方法
CN106676161B (zh) * 2017-01-03 2020-01-21 北京中检葆泰生物技术有限公司 一种用于微生物法定量检测烟酸的微孔板、其试剂盒及其制备方法
US10617756B2 (en) 2017-01-05 2020-04-14 Shimojani, LLC Drug regimen for treatment of cerebral ischemia
WO2018201154A1 (fr) * 2017-04-28 2018-11-01 Universal Stabilization Technologies, Inc. Vaccins antipoliomyélitiques thermostables antigéniques et procédés associés
CN110678590B (zh) 2017-05-31 2022-07-19 爱德华兹生命科学公司 胶原纤维和由其形成的制品
CN111970933A (zh) 2017-10-18 2020-11-20 埃斯库斯生物科技股份公司 通过施用微生物或其纯化菌株的合成生物集合体来提高禽类产量
CR20200194A (es) 2018-01-23 2020-11-04 Edwards Lifesciences Corp Método para el estiramiento previo de materiales biocompatibles implantables y materiales y dispositivos producidos a medida
JP7138336B2 (ja) * 2018-06-29 2022-09-16 国立大学法人九州工業大学 生体由来の水溶性高分子乾燥品の製造方法及びその製造装置
US11517428B2 (en) 2018-11-01 2022-12-06 Edwards Lifesciences Corporation Transcatheter pulmonic regenerative valve

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987000196A1 (fr) * 1985-07-09 1987-01-15 Quadrant Bioresources Limited Protection des proteines et similaires
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
US5271881A (en) * 1987-09-28 1993-12-21 Redding Bruce K Apparatus and method for making microcapsules
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
US5200399A (en) * 1990-09-14 1993-04-06 Boyce Thompson Institute For Plant Research, Inc. Method of protecting biological materials from destructive reactions in the dry state
AU659645B2 (en) * 1991-06-26 1995-05-25 Inhale Therapeutic Systems Storage of materials
US5409703A (en) * 1993-06-24 1995-04-25 Carrington Laboratories, Inc. Dried hydrogel from hydrophilic-hygroscopic polymer
US5565318A (en) * 1994-09-02 1996-10-15 Pharmacia Biotech, Inc. Room temperature stable reagent semi-spheres
CZ391297A3 (cs) * 1995-06-07 1998-05-13 Quadrant Holdings Cambridge Limited Způsob přípravy tenké porovité skelné matrice a prostředek tím získaný

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