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WO1998000551A3 - Gene codant la synthase hyaluronan - Google Patents

Gene codant la synthase hyaluronan Download PDF

Info

Publication number
WO1998000551A3
WO1998000551A3 PCT/US1997/011761 US9711761W WO9800551A3 WO 1998000551 A3 WO1998000551 A3 WO 1998000551A3 US 9711761 W US9711761 W US 9711761W WO 9800551 A3 WO9800551 A3 WO 9800551A3
Authority
WO
WIPO (PCT)
Prior art keywords
hyaluronan synthase
gene encoding
encoding hyaluronan
isolated
purified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1997/011761
Other languages
English (en)
Other versions
WO1998000551A2 (fr
Inventor
John A Mcdonald
Andrew P Spicer
Mary Louise Augustine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mayo Foundation for Medical Education and Research
Mayo Clinic in Florida
Original Assignee
Mayo Foundation for Medical Education and Research
Mayo Clinic in Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/675,499 external-priority patent/US6492150B1/en
Application filed by Mayo Foundation for Medical Education and Research, Mayo Clinic in Florida filed Critical Mayo Foundation for Medical Education and Research
Priority to AU36522/97A priority Critical patent/AU3652297A/en
Publication of WO1998000551A2 publication Critical patent/WO1998000551A2/fr
Publication of WO1998000551A3 publication Critical patent/WO1998000551A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne l'isolement et la purification d'une molécule d'ADN codant la synthase-2 hyaluronan (Has2), comme on purifie et isole un polypeptide Has2. L'invention concerne également l'isolement et la purification d'une molécule d'ADN codant la synthase-3 hyaluronan (Has3), comme on purifie et isole un polypeptide Has3.
PCT/US1997/011761 1996-07-03 1997-07-03 Gene codant la synthase hyaluronan Ceased WO1998000551A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU36522/97A AU3652297A (en) 1996-07-03 1997-07-03 Gene encoding hyaluronan synthase

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/675,499 US6492150B1 (en) 1996-07-03 1996-07-03 Gene encoding hyaluronan synthase
US08/675,499 1996-07-03
US08/812,008 1997-03-05
US08/812,008 US6602693B1 (en) 1996-07-03 1997-03-05 Gene encoding hyaluronan synthase

Publications (2)

Publication Number Publication Date
WO1998000551A2 WO1998000551A2 (fr) 1998-01-08
WO1998000551A3 true WO1998000551A3 (fr) 1998-03-26

Family

ID=27101351

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/011761 Ceased WO1998000551A2 (fr) 1996-07-03 1997-07-03 Gene codant la synthase hyaluronan

Country Status (3)

Country Link
US (1) US6602693B1 (fr)
AU (1) AU3652297A (fr)
WO (1) WO1998000551A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162908A (en) * 1996-04-05 2000-12-19 Seikagaku Corporation Polypeptide of human-origin hyaluronate synthetase and DNA encoding the same
US5994100A (en) * 1997-05-29 1999-11-30 Smithkline Beecham Corporation HAS2 splicing variant HOEFC11: a target in chronic renal failure, inflammatory diseases and myocardial ischemia
ES2235378T3 (es) * 1997-10-31 2005-07-01 The Board Of Regents Of The University Of Oklahoma Gen de la hialuronan sintasa y usos del mismo.
US6867352B2 (en) 1998-07-14 2005-03-15 E. I. Du Pont De Nemours And Company Plant cellulose synthases
WO2000004166A2 (fr) * 1998-07-14 2000-01-27 E.I. Du Pont De Nemours And Company Cellulose synthases vegetales
WO2003006068A1 (fr) * 2001-07-10 2003-01-23 Clear Solutions Biotech, Inc. Therapie genique pour le syndrome d'oeil sec
CN1882602B (zh) 2003-10-10 2011-02-09 阿尔卡米亚肿瘤股份有限公司 在疾病治疗中乙酰透明质酸合成的调节和降解
US8460658B2 (en) 2003-10-10 2013-06-11 Alchemia Oncology Pty Limited Method of treating cancer and/or cellular proliferative conditions and agents targeting hyaluronan anabolism useful for same
AU2004279475B2 (en) * 2003-10-10 2011-05-12 Alchemia Oncology Pty Limited The moduilation of hyaluronan synthesis and degradation in the treatment of disease
KR20100094982A (ko) * 2007-11-13 2010-08-27 바이오-테크널러지 제너럴 (이스라엘) 리미티드 점탄성 바이오폴리머의 희석식 여과 멸균 방법
KR102726294B1 (ko) 2014-01-31 2024-11-06 팩터 바이오사이언스 인크. 핵산 제조 및 송달을 위한 방법 및 산물
CN104263666B (zh) * 2014-09-12 2017-07-14 江南大学 一种产小分子透明质酸的重组毕赤酵母及其构建方法
EP3543339A1 (fr) 2015-02-13 2019-09-25 Factor Bioscience Inc. Produits d'acides nucléiques et leurs procédés d'administration
CN109803977B (zh) 2016-08-17 2023-03-17 菲克特生物科学股份有限公司 核酸产品及其施用方法
CN114450265B (zh) 2019-07-03 2024-12-24 菲克特生物科学股份有限公司 阳离子脂质及其用途
US10501404B1 (en) 2019-07-30 2019-12-10 Factor Bioscience Inc. Cationic lipids and transfection methods

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
CARLOS E. SEMINO ET AL.: "Homologs of the Xenopus developmental gene DG42 are present in zebrafish and mouse and are involved in the synthesis of Nod-like chitin oligosaccharides during early embriogenesis", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 93, no. 10, 14 May 1996 (1996-05-14), WASHINGTON US, pages 4548 - 4553, XP002041499 *
FUELOEP, CSABA ET AL: "Coding sequence of a hyaluronan synthase homolog expressed during expansion of the mouse cumulus-oocyte complex", ARCH. BIOCHEM. BIOPHYS. (1997), 337(2), 261-266 CODEN: ABBIA4;ISSN: 0003-9861, 1997, XP002041503 *
ITANO N ET AL: "Expression cloning and molecular characterization of HAS protein, a eukaryotic hyaluronan synthase.", ANNUAL MEETING OF THE 6TH INTERNATIONAL CONGRESS ON CELL BIOLOGY AND THE 36TH AMERICAN SOCIETY FOR CELL BIOLOGY, SAN FRANCISCO, CALIFORNIA, USA, DECEMBER 7-11, 1996. MOLECULAR BIOLOGY OF THE CELL 7 (SUPPL.). 1996. 55A. ISSN: 1059-1524, XP002041507 *
ITANO, NAOKI ET AL: "Molecular cloning of human hyaluronan synthase", BIOCHEM. BIOPHYS. RES. COMMUN. (1996), 222(3), 816-820 CODEN: BBRCA9;ISSN: 0006-291X, 1996, XP002041498 *
NAOKI ITANO ET AL.: "Expression cloning and molecular characterization of HAS protein, a eukaryotic hyaluronan synthase", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 17, 26 April 1996 (1996-04-26), MD US, pages 9875 - 9878, XP002041497 *
SPICER A P ET AL: "Molecular cloning of a putative eukaryotic hyaluronan synthase, mHas2.", ANNUAL MEETING OF THE 6TH INTERNATIONAL CONGRESS ON CELL BIOLOGY AND THE 36TH AMERICAN SOCIETY FOR CELL BIOLOGY, SAN FRANCISCO, CALIFORNIA, USA, DECEMBER 7-11, 1996. MOLECULAR BIOLOGY OF THE CELL 7 (SUPPL.). 1996. 55A. ISSN: 1059-1524, XP002041505 *
SPICER A P ET AL: "Molecular cloning of a putative eukaryotic hyaluronan synthase, mHAS2.", ANNUAL MEETING OF THE PROFESSIONAL RESEARCH SCIENTISTS ON EXPERIMENTAL BIOLOGY 97, NEW ORLEANS, LOUISIANA, USA, APRIL 6-9, 1997. FASEB JOURNAL 11 (3). 1997. A533. ISSN: 0892-6638, XP002041504 *
SPICER, ANDREW P. ET AL: "Molecular cloning and characterization of a putative mouse hyaluronan synthase", J. BIOL. CHEM. (1996), 271(38), 23400-23406 CODEN: JBCHA3;ISSN: 0021-9258, 1996, XP002041500 *
WATANABE K ET AL: "CHASE, cDNA for HA synthesis enhancement, encodes a putative human HA synthase.", ANNUAL MEETING OF THE 6TH INTERNATIONAL CONGRESS ON CELL BIOLOGY AND THE 36TH AMERICAN SOCIETY FOR CELL BIOLOGY, SAN FRANCISCO, CALIFORNIA, USA, DECEMBER 7-11, 1996. MOLECULAR BIOLOGY OF THE CELL 7 (SUPPL.). 1996. 56A. ISSN: 1059-1524, XP002041506 *
WATANABE, KEN ET AL: "Molecular identification of a putative human hyaluronan synthase", J. BIOL. CHEM. (1996), 271(38), 22945-22948 CODEN: JBCHA3;ISSN: 0021-9258, 1996, XP002041501 *
WEIGEL P H ET AL: "Hyaluronan synthases.", JOURNAL OF BIOLOGICAL CHEMISTRY 272 (22). 1997. 13997-14000. ISSN: 0021-9258, XP002041502 *

Also Published As

Publication number Publication date
US6602693B1 (en) 2003-08-05
AU3652297A (en) 1998-01-21
WO1998000551A2 (fr) 1998-01-08

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