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WO1997030331B1 - Submicron imaging system having an acousto-optic tunable filter - Google Patents

Submicron imaging system having an acousto-optic tunable filter

Info

Publication number
WO1997030331B1
WO1997030331B1 PCT/US1997/002265 US9702265W WO9730331B1 WO 1997030331 B1 WO1997030331 B1 WO 1997030331B1 US 9702265 W US9702265 W US 9702265W WO 9730331 B1 WO9730331 B1 WO 9730331B1
Authority
WO
WIPO (PCT)
Prior art keywords
filter
additionally
prism
camera
control circuit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1997/002265
Other languages
French (fr)
Other versions
WO1997030331A1 (en
Filing date
Publication date
Priority claimed from US08/603,035 external-priority patent/US5796512A/en
Application filed filed Critical
Priority to IL12558597A priority Critical patent/IL125585A/en
Priority to EP97905943A priority patent/EP0880683B1/en
Priority to AU22719/97A priority patent/AU2271997A/en
Priority to DE69713286T priority patent/DE69713286T2/en
Publication of WO1997030331A1 publication Critical patent/WO1997030331A1/en
Publication of WO1997030331B1 publication Critical patent/WO1997030331B1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Abstract

A two-dimensional imaging system comprises an acousto-optic tunable filter (38) for receiving light at an input end thereof and outputting light at an output end thereof. A control circuit (17) is provided for tuning the filter (38). A prism (96) is responsive to the light output by the tunable filter (38). The prism (96) is oriented at an angle with respect to the filter (38) to compensate for dispersion of the output light caused by the tunable filter (38). An output device such as a lens (36) or camera (40) is responsive to the prism (96) for forming a two-dimensional image.

Claims

33AMENDED CLAIMS[received by the Intemational Bureau on 5 August 1997 (05.08.97); original claims 1-21 replaced by amended claims 1-19 (3 pages)]
1. A system comprising an acousto-optic tunable filter (38) for receiving light at an input end thereof and outputting light at an output end thereof; a control circuit (17) for tuning said filter (38); and an objective lens (36) for collecting florescence from a sample plane (31) for input to said input end of said acousto-optic filter (38); the improvement comprising a prism (96) responsive to light output at. said output end of said filter (38), said prism (96) being oriented at an angle with respect to said filter (38) to compensate for dispersion of said output light caused by said filter (38) .
2. The system of claim 1 additionally comprising a camera (40) for receiving light output from said prism
(96) .
3. The system of claim 2 additionally comprising a controller (42) connected to the camera (40) for controlling the camera (40), and a processor (44) connected to the controller (42) for processing the images.
4. The system of claim 3 wherein said processor (44) includes a memory for storing the processed image.
5. The system of claim 1 additionally comprising a dichroic filter (100) positioned such that said objective lens (36) illuminates the sample plane (31) and collects light fluoresced from the sample plane (31) . 34
6. The system of claim 1 additionally comprising a dark-field condenser (30) positioned to illuminate the sample plane (31) .
7. The system of claim 1 additionally comprising a bright-field condenser (30) positioned to illuminate the sample plane (31) .
8. The system of claim 1 wherein said filter (38) includes an apodized crystal.
9. The system of claim 1 wherein said filter (38) includes a tellurium dioxide crystal.
10. The system of claim 9 wherein said tellurium dioxide crystal includes a crystal approximately five centimeters in length.
11. The system of claim 1 wherein said control circuit (17) includes a control circuit for rapidly switching the wavelength at which said filter (38) is tuned.
12. The system of claim 1 wherein said control circuit (17) includes a control circuit for rapidly turning said filter (38) on and off.
13. The system of claim 1 wherein said system includes a two-dimensional imaging system, and wherein said objective lens forms a two-dimensional image from the collected florescence.
14. A system, comprising: a dark-field condenser positioned to illuminate a sample plane (31) ; an objective lens (36) positioned to collect fluorescence from the sample plane (31); an acousto-optic tunable filter (38) for receiving light from said objective lens (36) ; and a control circuit for tuning said filter (38) .
15. The system of claim 14 additionally comprising a prism (96) responsive to the light output by said filter (38), said prism (96) being oriented at an angle with respect to said filter (38) to compensate for dispersion of output light caused by said tunable filter (38) .
16. The system of claim 14 wherein said tunable filter (38) includes an apodized crystal.
17. The system of claim 14 additionally comprising a camera (40) for receiving light output from said filter (38) .
18. The system of claim 17 additionally comprising a controller (42) connected to the camera (40) for controlling the camera (40), and a processor (44) connected to the controller (42) for processing the images.
19. The system of claim 18 wherein said processor (44) includes a memory for storing the processed image.
PCT/US1997/002265 1996-02-16 1997-02-14 Submicron imaging system having an acousto-optic tunable filter Ceased WO1997030331A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IL12558597A IL125585A (en) 1996-02-16 1997-02-14 Submicron imaging system having an acousto-optic tunable filter
EP97905943A EP0880683B1 (en) 1996-02-16 1997-02-14 Submicron imaging system having an acousto-optic tunable filter
AU22719/97A AU2271997A (en) 1996-02-16 1997-02-14 Submicron imaging system having an acousto-optic tunable filter
DE69713286T DE69713286T2 (en) 1996-02-16 1997-02-14 SUBMICRON RESOLUTION IMAGE SYSTEM WITH TUNABLE ACUSTO-OPTICAL FILTER

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/603,035 US5796512A (en) 1996-02-16 1996-02-16 Subicron imaging system having an acousto-optic tunable filter
US08/603,035 1996-02-16

Publications (2)

Publication Number Publication Date
WO1997030331A1 WO1997030331A1 (en) 1997-08-21
WO1997030331B1 true WO1997030331B1 (en) 1997-09-25

Family

ID=24413817

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/002265 Ceased WO1997030331A1 (en) 1996-02-16 1997-02-14 Submicron imaging system having an acousto-optic tunable filter

Country Status (6)

Country Link
US (1) US5796512A (en)
EP (1) EP0880683B1 (en)
AU (1) AU2271997A (en)
DE (1) DE69713286T2 (en)
IL (1) IL125585A (en)
WO (1) WO1997030331A1 (en)

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US9354370B1 (en) 2007-09-25 2016-05-31 Semrock, Inc. Optical thin-film notch filter with very wide pass band regions
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