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WO1997025087A1 - Dispenser for a therapeutic substance - Google Patents

Dispenser for a therapeutic substance Download PDF

Info

Publication number
WO1997025087A1
WO1997025087A1 PCT/NL1997/000004 NL9700004W WO9725087A1 WO 1997025087 A1 WO1997025087 A1 WO 1997025087A1 NL 9700004 W NL9700004 W NL 9700004W WO 9725087 A1 WO9725087 A1 WO 9725087A1
Authority
WO
WIPO (PCT)
Prior art keywords
dispenser
therapeutic substance
carrier body
ofthe
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/NL1997/000004
Other languages
French (fr)
Dutch (nl)
Inventor
Johannes Gerrit De Graaf
Charles Aurelius Sumajow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SUMAJOW HOLDING BV
LANGRIDGE INVESTMENTS LLC
Original Assignee
SUMAJOW HOLDING BV
LANGRIDGE INVESTMENTS LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SUMAJOW HOLDING BV, LANGRIDGE INVESTMENTS LLC filed Critical SUMAJOW HOLDING BV
Priority to EP97900479A priority Critical patent/EP0885028A1/en
Priority to AU14005/97A priority patent/AU1400597A/en
Publication of WO1997025087A1 publication Critical patent/WO1997025087A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G21/00Supporting or protective framework or housings for endless load-carriers or traction elements of belt or chain conveyors
    • B65G21/16Supporting or protective framework or housings for endless load-carriers or traction elements of belt or chain conveyors for conveyors having endless load-carriers movable in curved paths
    • B65G21/18Supporting or protective framework or housings for endless load-carriers or traction elements of belt or chain conveyors for conveyors having endless load-carriers movable in curved paths in three-dimensionally curved paths
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0011Details of inhalators; Constructional features thereof with microcapsules, e.g. several in one dose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0031Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G47/00Article or material-handling devices associated with conveyors; Methods employing such devices
    • B65G47/34Devices for discharging articles or materials from conveyor 
    • B65G47/46Devices for discharging articles or materials from conveyor  and distributing, e.g. automatically, to desired points
    • B65G47/51Devices for discharging articles or materials from conveyor  and distributing, e.g. automatically, to desired points according to unprogrammed signals, e.g. influenced by supply situation at destination
    • B65G47/5104Devices for discharging articles or materials from conveyor  and distributing, e.g. automatically, to desired points according to unprogrammed signals, e.g. influenced by supply situation at destination for articles
    • B65G47/5109Devices for discharging articles or materials from conveyor  and distributing, e.g. automatically, to desired points according to unprogrammed signals, e.g. influenced by supply situation at destination for articles first In - First Out systems: FIFO
    • B65G47/5113Devices for discharging articles or materials from conveyor  and distributing, e.g. automatically, to desired points according to unprogrammed signals, e.g. influenced by supply situation at destination for articles first In - First Out systems: FIFO using endless conveyors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G2207/00Indexing codes relating to constructional details, configuration and additional features of a handling device, e.g. Conveyors
    • B65G2207/24Helical or spiral conveying path

Definitions

  • the invention relates to a dispenser for a therapeutic substance which is to be taken in through the respiratory tract, which dispenser contains at least one dose of said
  • the therapeutic substance may comprise a regular prescribed drug or a homeopathic
  • drug here which is to be administered orally or nasally, or alternatively may comprise an
  • active ingredient ofa kind as used in alternative therapeutic methods of treatment such as aroma therapy, where aromatic substances and aromatic oils are used for achieving
  • the therapeutic substance in which the therapeutic substance is present in liquid form and by means of which it is
  • a spray bottle with a capacity which is much greater than required for one or a few day(s) will have an unecessarily great weight and volume.
  • a dispenser in the form of a so-called inhaler partly eliminates these disadvantages
  • the present invention has for its object to provide a dispenser ofthe kind mentioned in
  • ingredient is always a product ofthe concentration with which and the surface area on
  • the carrier body accordingly need not be larger than a small card
  • airtight seal is simply opened for intake, for example through scratching, pulling,
  • dispenser according to the invention can be manufactured at very low
  • the carrier body may thus comprise a single dose ofthe therapeutic substance, but in a
  • the carrier body supports a number of individual doses in a number of separate regions
  • the empty carrier body may be simply discarded after the last dose has been used.
  • the active ingredient may be provided in that the carrier body is permeated therewith,
  • microbeads minute airtight globules, so-called microbeads, which are laminated onto the carrier
  • the substance may be taken in in that the region with the microbeads is scratched
  • Fig. 1 is a plan view
  • Fig. 2 is a cross-section taken on the line II-II in Fig. 1 of an embodiment ofthe
  • Figs. 1 and 2 show an embodiment ofthe dispenser according to the invention, in plan
  • the therapeutic substance may be, for example, a regular prescribed drug which is to be inhaled through the nose or mouth for having its effect, or may alternatively comprise an aromatic or homeopathic substance for use in aroma therapy
  • the dispenser comprises a card-shaped carrier body 10 made of paper, cardboard, a
  • Such a format has the advantage that many wallets, purses, and the like have compartments for accommodating cards of this size.
  • the dispenser can thus be carried
  • the therapeutic substance is for this purpose accommodated in so-called microbeads 11, i.e. minute globules of synthetic resin which are provided in
  • the therapeutic substance does lie hermetically enclosed therein, but it can be released by hand in a comparatively simple
  • the amounts contained in the final doses (1...5) can be increased or reduced as desired in that the concentrations ofthe active ingredients in the beads are varied. It is obviously
  • therapeutic substance in a certain region may be indicated, for example, by means of a
  • the carrier body also comprises a field 12 which offers a space for commercial texts or
  • the invention thus offers a
  • dispenser for a therapeutic substance which is easy to carry on which one or several
  • the carrier body prefferably, imbued with the therapeutic substance
  • carrier body should comprise a porous, or at least permeable material for this purpose.
  • the carrier body is then sealed off afterwards with an airtight (plastic) foil in those areas
  • the active substance can be released in that the package is opened or the foil is removed
  • the carrier body have to be rectangular, indeed, other shapes such as polygonal, circular, or

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)

Abstract

A dispenser for a therapeutic substance which is to be taken in through the respiratory tract comprises a card-shaped carrier body (10). At least one dose (1...5) of the therapeutic substance is present at a surface of this carrier. The therapeutic substance is present in a form (11) which is sealed off in an airtight manner but which can be opened by hand. The therapeutic substance can thus be carried on the person in an extremely convenient format and is available for use at all times.

Description

Dispenser for a therapeutic substance
The invention relates to a dispenser for a therapeutic substance which is to be taken in through the respiratory tract, which dispenser contains at least one dose of said
substance.
The therapeutic substance may comprise a regular prescribed drug or a homeopathic
drug here which is to be administered orally or nasally, or alternatively may comprise an
active ingredient ofa kind as used in alternative therapeutic methods of treatment such as aroma therapy, where aromatic substances and aromatic oils are used for achieving
the desired curative effect.
Dispensers of various kinds exist especially for pharmaceutical substances for combating conditions ofthe respiratory tract and the lungs. Thus there are spray bottles
in which the therapeutic substance is present in liquid form and by means of which it is
sprayed into the mouth or nose so as to be absorbed therein. A disadvantage of such dispensers, however, is the inaccurate dosage ofthe active ingredient. In addition, the
bottle usually contains much more ofthe therapeutic sibstance than will be used in a day or couple of days. This is a disadvantage especially for the substances mentioned above
because they are usually taken along by the user in order to have the substance available at all times. A spray bottle with a capacity which is much greater than required for one or a few day(s) will have an unecessarily great weight and volume. -2- A dispenser in the form of a so-called inhaler partly eliminates these disadvantages
because it is possible to introduce capsules therein which contain the therapeutic
substance in an accurately measured dose in liquid or powder form. The user then need
not carry more capsules daily than are required for one or several days. Nevertheless,
such an inhaler still occupies comparatively much space and is in addition
comparatively expensive.
The present invention has for its object to provide a dispenser ofthe kind mentioned in
the opening paragraph which can be inexpensively manufactured, which is small,
compact, and thus easy to carry, and with which an accurate dose ofthe active
ingredient can be measured out.
According to the invention, a dispenser ofthe kind mentioned in the opening paragraph
is for this purpose characterized in that the dispenser comprises a card-shaped carrier
body at a surface of which said dose is present in a form which is sealed off in an
airtight manner but which can be manually opened. Since the quantity ofthe active
ingredient is always a product ofthe concentration with which and the surface area on
which it has been provided, one or several doses can be accommodated on a small
surface area already. The carrier body accordingly need not be larger than a small card
which can be easily and unobtrusively kept, for example, in a wallet. The therapeutic
substance remains sealed off hermetically as long as the dispenser is not used. The
airtight seal is simply opened for intake, for example through scratching, pulling,
pressing, or some other method of penetration. Only then is the active ingredient released in an exact dose as previously provided on the carrier body. It is found in
practice that the dispenser according to the invention can be manufactured at very low
cost, for example by a printing technique.
The carrier body may thus comprise a single dose ofthe therapeutic substance, but in a
preferred embodiment the dispenser according to the invention is characterized in that
the carrier body supports a number of individual doses in a number of separate regions
ofthe surface which are identified as such. It is possible in that case to accommodate the
intake requirement for e.g. a full day, week, or other period of time on one and the same
carrier body, only that dose which is required at any moment being opened each time.
The empty carrier body may be simply discarded after the last dose has been used.
It is possible not only to accommodate a multiple ofthe same dose on the carrier body,
but also - as in a special embodiment ofthe invention - to provide the therapeutic
substance in different doses on the carrier body, or to provide a number of different
therapeutic substances next to one another, whether or not in multiple doses which may
or may not be equal. Different doses may then be realized by means of proportionally
different surface areas ofthe regions in which the doses are provided, but also, for
example, in that a different concentration of the active ingredient is used on a surface
area which may remain the same.
The active ingredient may be provided in that the carrier body is permeated therewith,
wholly or localy, or in that the substance is laminated onto the carrier body, whereupon the regions are covered by means of, for example, an airtight plastic foil. The active
ingredient can be released in that the foil is pierced locally. A further special
embodiment ofthe dispenser according to the invention, however, is characterized in
that the therapeutic substance is enclosed in airtight microbeads which are provided in
one or several regions on the surface. The active ingredient in this case lies enclosed in
minute airtight globules, so-called microbeads, which are laminated onto the carrier
body. The substance may be taken in in that the region with the microbeads is scratched
with a nail or a hard object, so that the globules burst open and the active ingredient is
released.
The invention will be explained in more detail below with reference to an embodiment
and the accompanying drawing in which:
Fig. 1 is a plan view, and
Fig. 2 is a cross-section taken on the line II-II in Fig. 1 of an embodiment ofthe
dispenser according to the invention.
The Figures are purely diagrammatic and not drawn true to scale. Some dimensions are
particularly exaggerated for the sake of clarity. Corresponding parts have been given the
same reference numerals as much as possible in the Figures.
Figs. 1 and 2 show an embodiment ofthe dispenser according to the invention, in plan
view and in cross-section, respectively, by means of which a therapeutic substance
designed for intake through the respiratory tract can be easily administered and
transported. The therapeutic substance may be, for example, a regular prescribed drug which is to be inhaled through the nose or mouth for having its effect, or may alternatively comprise an aromatic or homeopathic substance for use in aroma therapy
or homeopathic treatments, in which former case, for example, selected aromatic substances and oils are used for counteracting a patient's compulsive behaviour, for
example cigarette smoking, drinking of alcoholic beverages, or excessive eating. Other
applications ofthe dispenser according to the invention are indeed very well
conceivable.
The dispenser comprises a card-shaped carrier body 10 made of paper, cardboard, a
suitable synthetic resin, or any other material, preferably in the standard credit card
format which is used to an ever-increasing extent nowadays, i.e. a format of 8.5 cm by
5.5 cm. Such a format has the advantage that many wallets, purses, and the like have compartments for accommodating cards of this size. The dispenser can thus be carried
in the same way as the user's credit cards and as a result is always immediately at hand.
Five individual doses ofthe therapeutic substance are stored in five separate regions
(1...5), which are identified as such, in an airtight manner at the surface of the carrier
body 10 in this example. The therapeutic substance is for this purpose accommodated in so-called microbeads 11, i.e. minute globules of synthetic resin which are provided in
the correct locations and in the correct quantities on the carrier body, cf. also Fig. 2, by a
printing technique which is known per se. The therapeutic substance does lie hermetically enclosed therein, but it can be released by hand in a comparatively simple
manner through scratching, pulling, pressing, or some other method of exerting pressure on the relevant region, so that the beads burst open locally and the active ingredient enclosed therein is set free. To take the therapeutic substance, therefore, all the user has
to do is scratch over the desired region containing the selected dose with his/her
fingernail or some hard object and sniff up or otherwise inhale the therapeutic substance
released in that manner. The unused doses remain hermetically sealed and accordingly available for later use.
The amounts contained in the final doses (1...5) can be increased or reduced as desired in that the concentrations ofthe active ingredients in the beads are varied. It is obviously
also possible to vary the total dose in a region by modifying the total surface area ofthe region accordingly. The total quantity of active ingredient in a given region will always
be given by the product ofthe concentration and the specific surface area ofthe region (1...5), provided the layer thickness is the same everywhere. It is thus possible to
provide equal as well as mutually different doses on the carrier body in one and the
same printing process, so that in the latter case the user can choose a heavier or lighter dose ofthe same therapeutic substance in dependence on his/her need ofthe moment. It is in addition possible to provide different therapeutic substances on one carrier body in
that the microbeads ofthe regions (1...5) are given different fillings. The type of
therapeutic substance in a certain region may be indicated, for example, by means ofa
suitable printed message on the carrier body on or below the relevant region. A printed message on the carrier body, whether on the upper or on the lower side, was found to
have no influence on the operation ofthe dispenser in general and on the effectiveness
ofthe therapeutic substance in particular. The carrier body also comprises a field 12 which offers a space for commercial texts or
instructions relating to the therapeutic substance. Such a message may obviously also be
provided on the back ofthe carrier body, in which case the space in the field 12 is
available for additional doses ofthe therapeutic substance. The invention thus offers a
dispenser for a therapeutic substance which is easy to carry, on which one or several
sealed doses ofthe therapeutic substance are accommodated, and which can in addition
accommodate printed instructions for its use.
Although the invention was explained in detail above with reference to only a single
embodiment, it will be obvious that the invention should by no means be regarded as
limited to the example given here. On the contrary, many variations and embodiments
are possible to those skilled in the art within the scope ofthe invention. Thus it is
possible for the carrier body to be, for example, imbued with the therapeutic substance
instead of supporting this substance provided thereon enclosed in microbeads. The
carrier body should comprise a porous, or at least permeable material for this purpose.
The carrier body is then sealed off afterwards with an airtight (plastic) foil in those areas
where it was imbued with the active substance, or is enclosed in an airtight package.
The active substance can be released in that the package is opened or the foil is removed
or broken, so that it can be breathed in orally or nasally.
It is also possible to use a carrier body of a larger or smaller size, so that it can
accommodate more doses or occupy less storage space, respectively. Neither does the carrier body have to be rectangular, indeed, other shapes such as polygonal, circular, or
oval are equally well possible.

Claims

Claims:
1. A dispenser for a therapeutic substance which is to be taken in through the respiratory tract, which dispenser contains at least one dose of said substance,
characterized in that the dispenser comprises a card-shaped carrier body at a surface of
which said dose is present in a form which is sealed off in an airtight manner but which can be manually opened.
2. A dispenser as claimed in Claim 1 , characterized in that the carrier body
comprises a number of individual doses in a number of separate regions ofthe surface which are identified as such.
3. A dispenser as claimed in any one or several ofthe preceding Claims,
characterized in that the therapeutic substance is provided in different doses in separate
regions which are identified as such.
4. A dispenser as claimed in any one or several ofthe preceding Claims,
characterized in that different therapeutic substances are provided at the surface in
separate regions which are identified as such.
5. A dispenser as claimed in any one or several ofthe preceding Claims,
characterized in that the therapeutic substance is enclosed in airtight microbeads which
are provided in one or several regions on the surface.
6. A dispenser as claimed in any one or several ofthe preceding Claims, characterized in that the carrier body has a credit card format of approximately 8.5 cm
by 5.5 cm.
7. A dispenser as claimed in any one or several of the preceding Claims,
characterized in that the therapeutic substance was provided on the carrier body by a
printing technique.
PCT/NL1997/000004 1996-01-12 1997-01-06 Dispenser for a therapeutic substance Ceased WO1997025087A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP97900479A EP0885028A1 (en) 1996-01-12 1997-01-06 Dispenser for a therapeutic substance
AU14005/97A AU1400597A (en) 1996-01-12 1997-01-06 Dispenser for a therapeutic substance

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1002078A NL1002078C2 (en) 1996-01-12 1996-01-12 Dispenser for a therapeutic.
NL1002078 1996-01-12

Publications (1)

Publication Number Publication Date
WO1997025087A1 true WO1997025087A1 (en) 1997-07-17

Family

ID=19762145

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL1997/000004 Ceased WO1997025087A1 (en) 1996-01-12 1997-01-06 Dispenser for a therapeutic substance

Country Status (4)

Country Link
EP (1) EP0885028A1 (en)
AU (1) AU1400597A (en)
NL (1) NL1002078C2 (en)
WO (1) WO1997025087A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6443152B1 (en) 2001-01-12 2002-09-03 Becton Dickinson And Company Medicament respiratory delivery device
US6644309B2 (en) 2001-01-12 2003-11-11 Becton, Dickinson And Company Medicament respiratory delivery device and method
US6722364B2 (en) 2001-01-12 2004-04-20 Becton, Dickinson And Company Medicament inhalation delivery devices and methods for using the same
WO2006071512A1 (en) * 2004-12-23 2006-07-06 3M Innovative Properties Company Inhalation devices
US7741266B2 (en) 2005-06-20 2010-06-22 Rotuba Extruders, Inc. Process for preparing scented cellulosics and products prepared thereby

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2516387A1 (en) * 1981-11-16 1983-05-20 Fabre Sa Pierre INHALER RELEASING PREDOSE QUANTITIES OF VOLATILE OR DRIVABLE ACTIVE INGREDIENT CONTAINED IN A VOLATILE EXCIPIENT CONTAINED IN PERIODICALLY DISTRIBUTED MICROCAPSULES, AS WELL AS SUCH SUPPORT AND PROCESS FOR PRODUCING THE SAME
US4553670A (en) * 1981-10-30 1985-11-19 Richard Collens Medical reminder device
US4889236A (en) * 1988-02-26 1989-12-26 Warner-Lambert Company Credit card-style medication package

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4553670A (en) * 1981-10-30 1985-11-19 Richard Collens Medical reminder device
FR2516387A1 (en) * 1981-11-16 1983-05-20 Fabre Sa Pierre INHALER RELEASING PREDOSE QUANTITIES OF VOLATILE OR DRIVABLE ACTIVE INGREDIENT CONTAINED IN A VOLATILE EXCIPIENT CONTAINED IN PERIODICALLY DISTRIBUTED MICROCAPSULES, AS WELL AS SUCH SUPPORT AND PROCESS FOR PRODUCING THE SAME
US4889236A (en) * 1988-02-26 1989-12-26 Warner-Lambert Company Credit card-style medication package

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6443152B1 (en) 2001-01-12 2002-09-03 Becton Dickinson And Company Medicament respiratory delivery device
US6644309B2 (en) 2001-01-12 2003-11-11 Becton, Dickinson And Company Medicament respiratory delivery device and method
US6722364B2 (en) 2001-01-12 2004-04-20 Becton, Dickinson And Company Medicament inhalation delivery devices and methods for using the same
US6929005B2 (en) 2001-01-12 2005-08-16 Becton, Dickinson And Company Medicament respiratory delivery device, cartridge and method of making same
US7270127B2 (en) 2001-01-12 2007-09-18 Becton, Dickinson And Company Medicament respiratory delivery device
WO2006071512A1 (en) * 2004-12-23 2006-07-06 3M Innovative Properties Company Inhalation devices
US7741266B2 (en) 2005-06-20 2010-06-22 Rotuba Extruders, Inc. Process for preparing scented cellulosics and products prepared thereby

Also Published As

Publication number Publication date
NL1002078C2 (en) 1997-07-15
EP0885028A1 (en) 1998-12-23
AU1400597A (en) 1997-08-01

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