[go: up one dir, main page]

WO1997016231A1 - Separateur a ultrasons pour particules en suspension - Google Patents

Separateur a ultrasons pour particules en suspension Download PDF

Info

Publication number
WO1997016231A1
WO1997016231A1 PCT/CN1995/000085 CN9500085W WO9716231A1 WO 1997016231 A1 WO1997016231 A1 WO 1997016231A1 CN 9500085 W CN9500085 W CN 9500085W WO 9716231 A1 WO9716231 A1 WO 9716231A1
Authority
WO
WIPO (PCT)
Prior art keywords
container
ultrasonic
suspended particles
ultrasonic generator
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN1995/000085
Other languages
English (en)
Chinese (zh)
Inventor
Xiaoqing Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TRUNK TECHNOLOGY GROUP
Original Assignee
TRUNK TECHNOLOGY GROUP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TRUNK TECHNOLOGY GROUP filed Critical TRUNK TECHNOLOGY GROUP
Priority to AU38385/95A priority Critical patent/AU3838595A/en
Priority to PCT/CN1995/000085 priority patent/WO1997016231A1/fr
Publication of WO1997016231A1 publication Critical patent/WO1997016231A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/003—Sedimentation tanks provided with a plurality of compartments separated by a partition wall
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/28—Mechanical auxiliary equipment for acceleration of sedimentation, e.g. by vibrators or the like

Definitions

  • the present invention relates to a device for separating suspended particles, especially particles, in a liquid or a gas by using ultrasound, especially a device for separating blood cells and plasma from blood. Background technique
  • centrifugation There are various methods for separating suspended particles in gas or liquid. The more common method is centrifugation. However, when separating small particles, especially in the case of blood cells and plasma separation, using a centrifugal separation device is not only very complicated, but also It is expensive and can easily cause damage to blood cells.
  • U.S. Patent No. 4,055,491 describes a device for ultrasonically separating suspended particles in a liquid.
  • the device includes horizontally propagating ultrasound to make suspended particles form flocculent aggregates in space. When the particles are settled by gravity, the ultrasonic source is turned off. A vertical settling tank is provided to help settling the particles.
  • the blood separation means can be used, but according to the scheme disclosed in this patent (Sheng thickness of the blood vessel 1M, ultrasonic frequency 2.7 ⁇ ⁇ ), the reflected ultrasonic wave due to fading caused in the blood reaches the region near the ultrasonic generator Later, the intensity is only 1/10 13 of the emission intensity, so the minimum conditions for separating blood have been lost, let alone applied to the clinic.
  • Chinese Patent Application No. 91105848.6 discloses an apparatus for separating suspended particles by using ultrasound.
  • the apparatus includes an ultrasonic generator driving circuit, an ultrasonic generator and a reflecting plate, and both the ultrasonic generator and the reflecting plate are cylindrical or arc-shaped. Shaped and placed concentrically.
  • One of the important applications of this instrument is to separate blood. Although the instrument can meet the requirements of blood separation, people still expect a more ideal device for separating suspended particles, especially a device for separating blood.
  • This An object of the invention is to provide a faster and more effective separation of suspended particles in a liquid or gas, especially particulate devices.
  • the present invention relates to a device for separating suspended particles, especially fine particles such as blood, by using ultrasound.
  • the device includes a first container with a reflective wall for containing a fluid with suspended particles, such as a gas or a liquid, or a matching liquid.
  • the reflective wall is used to reflect ultrasonic waves.
  • An ultrasonic generator is located in the first container, so that The suspended particles carried by the fluid form a flocculent aggregation zone with space intervals under the action of ultrasonic waves, and settle under the action of gravity.
  • There is an angle ⁇ between them There is an angle ⁇ between them.
  • a device for separating suspended particles, especially small particles such as blood, by using ultrasound includes a first container with a reflective wall for containing a matching liquid, and an ultrasonic generator located in the first container.
  • Figure 1 is a schematic diagram of the process of separating blood cells from plasma when separating blood according to one embodiment of the present invention.
  • FIG. 2 is a schematic diagram of a process of settling suspended particles and a corresponding flow field in some different embodiments of the present invention, where:
  • 2A, B, and C are schematic diagrams of the process of settlement of suspended particles and the corresponding flow field when the reflective wall is cylindrical and the second container is a hollow circular table;
  • 2D, ⁇ , and F are schematic diagrams of the sedimentation process of the suspended particles and the corresponding flow field when the reflecting wall is a circular truncated cone and the second container is a hollow cylinder (the bottom is a wedge);
  • Figure 2G and ⁇ are schematic diagrams of the sedimentation process of suspended particles and the corresponding flow field when the reflective wall is cylindrical and the second container is wedge-shaped.
  • Figures 3A-L are schematic diagrams of several different structural combinations of an ultrasonic generator, a reflecting wall and a second container according to the present invention.
  • Figure 4 is a schematic diagram of a blood separation device according to the present invention, wherein the reflecting wall and the ultrasound generator are both round-shaped, and the second container is a hollow round-shaped body.
  • Figure 5 shows another blood separation device according to the present invention.
  • Fig. 6 is a schematic diagram of a blood separation system according to the present invention.
  • FIG. 7 is a flowchart of a blood separation system
  • 8A-F are schematic diagrams of a second container designed according to some embodiments of the present invention.
  • Figure 9 is a schematic diagram of an apparatus for separating dust from a gas phase according to the present invention.
  • FIG. 10 is a schematic diagram of two embodiments according to the present invention with an included angle between an ultrasonic incident wave and an ultrasonic reflected wave.
  • the inventors After long-term research, the inventors have unexpectedly found that when using ultrasonic waves to separate suspended particles from fluids such as liquids or gases, especially small particles such as blood cells in blood, the settling distance of the suspended particles to the vessel wall is shortened. It can accelerate the separation of suspended particles and improve the separation efficiency. The improvement of this separation effect is presumed to be caused by the resistance of the suspended particles falling along the wall of the container to less than the resistance of the suspended particles falling in the suspension medium.
  • the inventor also unexpectedly particles The method of forming flocculent aggregates, if there is an angle between the ultrasonic incident wave and the ultrasonic reflected wave, it can also accelerate the separation of suspended particles and greatly improve the separation efficiency.
  • a device for separating suspended particles by using ultrasound includes a first container with a reflective wall, which is used to hold a matching liquid that is beneficial to ultrasonic conduction, a second container, which is used to hold a liquid with suspended particles, and an ultrasonic generator. And an ultrasonic driver, the second container and the ultrasonic generator are both located in the first container, and the second container is located between the reflective wall and the ultrasonic generator. The ultrasonic driver is used to drive the ultrasonic generator.
  • the ultrasonic wave generated by the ultrasonic generator is transmitted in the matching liquid, and interacts with the reflected wave reflected by the reflection wall to form a standing wave field, so that the suspended particles in the second container form space-like floc aggregates, Floc-like aggregated suspended particles settle under the action of gravity.
  • the structure of the second container is such that the settling distance of at least part of the suspended particles to the wall of the second container is less than that of the suspended particles to the second container Settlement distance at the bottom horizontal plane.
  • at least a part of the wall surface is cut at an angle ⁇ with the horizontal plane and intersects with the settlement direction of the suspended particles.
  • At least 1/5 of the wall surface of the second container that is in contact with the fluid forms an angle ⁇ with the horizontal plane and intersects the sedimentation direction of the suspended particles.
  • the angle ⁇ is 30 °- 85 °, preferably 45 ° -85 °.
  • the mutual position and / or structure of the reflective wall and the ultrasonic generator is designed so that an angle ⁇ is formed between the ultrasonic incident wave generated by the ultrasonic generator and the ultrasonic reflected wave reflected from the reflective wall.
  • the included angle ⁇ ranges from 5 ° to 90 °, preferably 10 ° to 80 °.
  • Figure 10 shows the included angle ⁇ between the incident ultrasonic wave and the reflected ultrasonic wave, where T is the space period.
  • the design of the second container is diverse.
  • the wall surface of the second container may be designed as an inclined surface, at least the inner wall surface is an inclined surface, or the lower part of the second container may be designed as a wedge shape or a part of an arc shape.
  • Some embodiments are shown in Figures 2 and 3.
  • 33 is a first container
  • 35 is a second container
  • 37 is a reflective wall
  • 39 is an ultrasonic generator. Obviously, ordinary technicians can easily figure out other embodiments, but still belong to the scope of the present invention.
  • the second container can also be formed by adding a plug-in board in the first container and combining it with the reflective wall of the first container. This can reduce the wall surface that the ultrasonic wave needs to penetrate, thereby reducing the transmission of the ultrasonic wave. attenuation.
  • the reflective wall can also be used as the wall or part of the first container.
  • Conventional reflective wall materials include, for example, stainless steel, copper, iron, aluminum, etc.
  • Polyvinyl chloride or polyethylene can also be used as the reflective wall material, especially When the reflecting wall also serves as the container wall of the second container.
  • the thickness of the wall of the second container should be selected to facilitate the transmission of ultrasound. Generally, the thinner is better, or the half wavelength of the ultrasonic wave used is used as the thickness.
  • the material of the second container should be as consistent as possible with the sound resistance of the object to be processed. Material.
  • the ultrasonic generator can have various vibration modes, such as radial vibration and thickness vibration. Generally, when the particle size of the suspended particles is large, a radial vibration mode with a low ultrasonic frequency is used, and when the particle size is small, a thickness vibration mode is used. For example, when processing blood, a thickness vibration mode is preferred.
  • a protective layer or matching layer can be added to the ultrasonic generator to prevent corrosion, and a reflective layer such as polytetrafluoroethylene can be added to the reflective wall to Protect reflective walls.
  • Figure 8 is several embodiments of the second container according to the present invention. In general, if to be The attenuation of the separation medium on ultrasound is large, and the span of the second container should be small. In Figure 8:
  • FIG. 2A to FIG. 2C corresponds to the case of the cylindrical reflecting wall and the second container with a hollow circular table body.
  • the suspended particles start to settle after forming the aggregation zone, and after reaching the container wall, they sink along the container wall, and the suspended particles are located on different aggregation zones. Convergence on the side wall of the container, and settling together, experiments have shown that such a flow field will help separation.
  • Figure 2D to Figure 2H show the settlement process and flow field in other cases.
  • Figures II to V sequentially show several time phases after the start of separation. Among them, I indicates that the blood cells are aggregated into stripes after the separation starts; II indicates that the blood cells fall after a certain time. A layer of blood-free zone is formed on the outer wall; III-IV shows continued separation, blood cells and plasma form two parts respectively, blood cells sink along the wall surface, and plasma rises along the wall surface; V shows the final result of separation: blood cells are separated from plasma,
  • the final separation time should obviously be the settling time of the blood cells at the top. It may be useful to analyze the path of the blood cells at the top. For vessels with vertical walls, the blood cells at the top will fall along the gravity field in a straight line. For vessels with inclined walls, Previously, the top red blood cells would first pass through the h section, and then fall along the wall with other blood cells. It may be that during this process, the friction between the blood cell surface and the plasma is significantly reduced as a whole, so that the blood cells settle during the entire descending process. The rate is increased,
  • the ultrasonic generator generates ultrasonic waves with the required frequency and power by driving the ultrasonic driver.
  • the ultrasonic driver can use common ultrasonic drivers and has multiple options. In order to prevent frequency drift, an automatic frequency tracking circuit can be added.
  • the ultrasonic frequency is generally It is related to the size of the suspended particles to be processed, and also to the nature of the object to be processed. For example, when separating blood, Too low an acoustic frequency will cause severe damage to red blood cells. Too high an ultrasonic frequency will increase the attenuation of the ultrasound, which is not good for separation. In blood separation, the ultrasonic frequency is usually 1-3MH Z.
  • the device of the present invention can separate suspended particles, especially small particles, carried by a variety of liquids or gases.
  • the device of the present invention is particularly suitable for processing blood to separate blood cells from plasma.
  • the device of the present invention can also be used in the pharmaceutical industry, food industry, etc. .
  • matching solution When selecting a matching solution, a variety of factors must be considered, that is, a substance that is close to the sound resistance of the object to be treated, and a substance that is less corrosive to the device.
  • the most commonly used matching solution is water, diluted sodium chloride aqueous solution such as 5% sodium chloride aqueous solution,
  • FIG. 3 shows some embodiments of the present invention. Obviously, other schemes can be changed by a person of ordinary skill according to the concept of the present invention, but these obviously belong to the scope of the present invention.
  • a device for separating suspended particles by using ultrasound includes a first container with a reflective wall for containing a fluid with suspended particles, such as a liquid or a gas, and an ultrasonic generator, where the ultrasonic generator is located at the first In the container, under the action of the ultrasonic wave generated by the ultrasonic generator, the suspended particles in the fluid form space-spaced floc aggregates and settle under the action of gravity.
  • the reflection wall reflecting the ultrasonic wave and the ultrasonic generator interact with each other.
  • the position and structure are designed so that there is an angle ⁇ between the ultrasonic incident wave emitted by the ultrasonic generator and the ultrasonic reflected wave coming back from the reflecting wall, and the included angle ⁇ is 5. -90 °, preferably 10. -80. .
  • the device also includes a second container.
  • the second container is located in the first container and between the reflective wall and the sonotrode.
  • the fluid with suspended particles will be contained in the second container, and the space formed by the first container and the ultrasonic generator will be used for containing the matching liquid to facilitate the ultrasonic wave. Delivery.
  • the second container may be a conventional container for ultrasonic separation, preferably using the second container described herein, the reflecting wall, the ultrasonic generator, the matching solution, etc. in the device, as described herein.
  • the particle density of the lower part of the container gradually increases. This has two effects: (1) the increase in density reduces the attenuation of ultrasonic waves and decreases the reflected wave amplitude, which relatively weakens the standing wave field effect; (2) the lower part gradually increases The thick accumulation zone is subject to increasing ultrasonic standing wave field forces (this force is periodic in space). For the first case, it is obvious that the power density of the ultrasound should be increased at the bottom; for the second case, In this case, the power density should be appropriately reduced.
  • ultrasonic generators with different shapes can be designed to meet the requirements of different suspended particles for different ultrasonic fields.
  • the points at a certain distance from the central axis on the horizontal are obviously the characteristics of the power density of the ultrasonic generator in the shape of a circular circle.
  • the power density of the ultrasonic generator in the cylindrical shape is obviously higher than that of the cylindrical ultrasonic generator. Large and small characteristics.
  • the containers shown by (D), (F), (I) have characteristics of large and small power density
  • (B), (G), ( H) belongs to upper, lower and larger
  • (A), (C), (J), (K), (L) are the same size from top to bottom.
  • a circular truncated or cylindrical shape is preferred.
  • An ultrasonic generator and a cylindrical or circular truncated first container, and the ultrasonic generator is coaxial with the first container. More preferably, the first surface of the reflecting surface normal direction at an angle to the horizontal plane.
  • the second container is coaxial with the first container.
  • the device of the present invention can also be used for separation of suspended particles upwards and media sedimentation.
  • the following will take the separation of blood as an example in conjunction with the drawings to explain the present invention in more detail.
  • FIG. 4 shows an ultrasonic separation device for separating bleeding cells from blood, which is an embodiment of the present invention.
  • the ultrasonic separation device in FIG. 4 includes a round-shaped ultrasonic generator 20, and a second container with a hollow round-shaped body. 30.
  • the first container 40 for holding the blood to be separated and a circular truncated reflecting wall.
  • the material of the second container 30 is selected from materials that are as consistent as possible with the sound resistance of the blood, such as polyethylene or polyvinyl chloride.
  • the second container 30 and the ultrasonic generator 20 are used for containing a matching liquid such as water or 5% sodium chloride.
  • the reflecting wall between the second container 30 and the first container 40 is also used for containing the matching liquid.
  • the material used for the reflective wall of the first container 40 is selected to be as large as possible and the acoustic impedance of the matching liquid is as large as possible.
  • the settling distance is smaller than the settling distance from the suspended particles to the horizontal cut plane of the bottom surface of the second container 30.
  • the axes of the ultrasonic generator 20, the second container 30, and the first container 40 are coincident with each other.
  • the vertical distance between the sonotrode 20 and the reflective wall of the first container can be selected according to the type and requirements of the processing.
  • the preferred vertical distance is an integer multiple of the half-wavelength of the ultrasonic wave used, so that a resonant cavity can be formed.
  • the second container 30 is also provided with inlets and outlets 31 and 32, which are used to introduce the blood to be separated and to export the separated blood cells and plasma and the exhaust gas.
  • the positions of the inlets and outlets 31 and 32 can be as required. To adjust.
  • the ultrasonic power density emitted by the ultrasonic generator is higher, lower, and lower, so that the blood cells at the bottom can be denser and the separation can be more thorough, and the upper blood cells will not be subjected to too much during the entire separation process. Radiation.
  • FIG. 5 is yet another embodiment of the present invention.
  • the ultrasonic generator 20 is cylindrical
  • the second container 30 is a hollow cylinder
  • the reflective wall of the first container 40 is a circular table.
  • a system for separating blood using ultrasound includes a blood collection device, a blood filtering device, a blood transfusion device, a blood separation device, and a control system, wherein the separation device is the ultrasonic separation device of the invention, and if necessary, the system further It may include a detection device for measuring the condition of the product and feedback to the system in time to make adjustments.
  • FIG. 7 shows a block diagram of an ultrasonic separation blood system.
  • Blood is obtained through a blood extraction device 201 and sent to a filtering device 202.
  • the filtered blood is input to an ultrasonic separation device 204 by a blood pumping device 203, and the blood is separated into products.
  • the useful part, that is, the blood cells are sent from the blood return system 205 to the place where blood is used or collected.
  • the control device 206 is used to control the operation of the system, while the detection device 207 is used to detect the information of the separation process and feed it back to the control Device 206 to adjust the operation of the system when needed.
  • the filter 150 is a filter-type filter, which includes a housing 152, a filter 153, and blood inlets and outlets 154 and 155.
  • the filtered blood enters the peristaltic pump 1 10 through the filtrate control valve 151, and then enters the ultrasonic separation device 100
  • the ultrasonic separation device 100 includes an ultrasonic generator 101, a blood storage container 102, and a reflecting wall 103, a blood inlet and outlet 104 for entering and exiting blood, and an auxiliary inlet and outlet 105 for exhausting gas in the container 102.
  • the system performs continuous blood separation, It can also be used as plasma inlet and outlet.
  • the waste is discharged into the collection bag 120 through the collection bag control valve 121, and the rest is mixed with the washing liquid from the peristaltic pump 110 and separated in the ultrasonic separation device 100
  • the separated supernatant is discharged into the collection bag 120, and the rest is sent to the blood collection bag 140 by the peristaltic pump 110 through the blood collection valve 141.
  • the ultrasonic separation blood system according to the present invention can be used not only for general blood separation Moreover, due to the good separation effect and fast separation speed, the blood separation operation can be continuously performed clinically to meet some special needs in the clinic.
  • FIG. 9 is a schematic diagram of a dust removal device according to the present invention.
  • the dust is separated from the gas phase.
  • the ultrasonic cylindrical wave has excellent symmetry, and there are no horizontal side lobes in the horizontal plane, so there is no interference caused by multiple reflections. Therefore, it has better separation effect than plane wave, which is very meaningful for processing gas.
  • the separation device is composed of a round table ultrasonic generator 20, a buffer layer 60, a collection container 50, and a stainless steel reflection plate 70.
  • the gas to be processed enters the buffer zone 60 through the inlet duct 61, and then enters the separation area between the ultrasonic generator and the reflection wall. After receiving the action of the standing wave field in the separation area, the dust forms agglomerates, then sinks and is collected Container collection. The gas passes through the separation zone to the buffer zone 80 and is then discharged from the outlet 81. In order to avoid disturbance of the gas in the flow, multiple inlets and outlets can also be added. Of course, intermittent separation can also be used.
  • the round truncated ultrasonic generator 20 is placed concentrically in the round truncated separation area. Outside the ultrasonic generator, a matching layer 209 with a certain thickness is also provided, in order to improve the effective separation space; to achieve acoustic matching, it can also reduce Corrosive substances in small gases corrode the transducer.
  • the optimal operating frequency of the transducer depends on the particle size in the gas. The smaller the particles, the higher the frequency. For example, the gas in the ink particles is carbon particles having a diameter of ⁇ to ⁇ , the best acoustic frequency of the transducer is 21 ⁇ ⁇ .
  • Example 1 is only used to illustrate the present invention, but not intended to limit the present invention.
  • Example 1 is only used to illustrate the present invention, but not intended to limit the present invention.
  • the ultrasonic generating device is cylindrical with a frequency of 2.5MH Z and the ultrasonic intensity is 0.06W / cm 2.
  • the reflecting wall is a stainless steel plate and the matching liquid is water. Take 200ml of human blood.
  • the blood container (such as the inclined wall container in this example) adopting the structure of the present invention has a separation effect at least 2.5 times better than that of the ordinary container (the straight wall container in this example). Is a very significant improvement.
  • Example 2
  • Example 3 The same device and the same operation steps as in Example 1 were used, but the angles ⁇ between the wall surface of the hollow round table blood container and the horizontal plane were changed to 85 °, 60 °, and 45, respectively. C, and maintain the same volume and materials.
  • the blood source is the same as in Example 1, and the results are shown in Table 3. Included angle ⁇ 85 ° 60 ° 45 ° Waste removal rate ⁇ 64 133 153 Example 3
  • Example 4 The same cylindrical ultrasonic generating device as in Example 1 was used, and a 10 ml test tube was used as the blood container. The operation steps were the same as those in Example 1, but the angle between the reflection wall and the vertical direction was changed so that the angle ⁇ between the ultrasonic incident wave and the reflected wave They are 0 °, 10 °, 30 ° and 60 °.
  • the test tube is placed vertically between the ultrasonic generator and the reflective wall, and the distance between the centerline of the test tube and the midpoint of the reflective wall from the axis of the ultrasonic generator is 25mm and 50mm, respectively. The results are shown in Table 4. Table 4 It can be seen that when there is an angle between the ultrasonic incident wave and the reflected wave, the separation effect is obviously better.
  • Example 4 It can be seen that when there is an angle between the ultrasonic incident wave and the reflected wave, the separation effect is obviously better.
  • Cylindrical ultrasound-generating device an ultrasonic frequency 2.5 ⁇ ⁇ , ultrasonic intensity 0.06W / cm 2, with a PVC material of the same thickness, making two blood filled containers.
  • a hollow cylindrical body A as high 50mm, an inner diameter of 136mm The outer diameter is 160mm.
  • the other is a hollow container B of the shape shown in FIG. 3A with a height of 50mm, an inner diameter of the upper end of 136mm, and an outer diameter of 163mm.
  • Two containers were filled with 100mJ of blood from the same blood source. The operating steps were the same as in Example 1 and the separation time was 5min. The results are shown in Table 5.
  • Waste removal rate% 40 59 The data in Table 5 show that the container produced according to the present invention has a significantly better separation effect than the container of the prior art. Those skilled in the art will be able to design other structures or give different solutions according to the concept of the present invention, and these structures or solutions are considered to belong to the scope of the present invention, including in the following claims.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • External Artificial Organs (AREA)

Abstract

La présente invention concerne un séparateur à ultrasons pour des particules en suspension dans une phase gazeuse ou liquide. Ce séparateur se compose d'une première enceinte pourvue d'une paroi réflecteur, d'un générateur d'ultrasons dans la première enceinte, et d'une seconde enceinte entre le générateur d'ultrasons et la paroi réflecteur. La première enceinte sert au confinement du matériau à séparer ou du liquide correspondant. La seconde enceinte sert au confinement du matériau à séparer. Les ondes d'ultrasons incidentes et réfléchies forment un angle entre elles. La seconde enceinte est conçue de sorte que les distances de repos d'une partie au moins des particules en suspension qui arrivent au plan tangent du niveau du fond de la seconde enceinte sont supérieures aux distances de repos des particules qui arrivent à la paroi de la seconde enceinte.
PCT/CN1995/000085 1995-10-30 1995-10-30 Separateur a ultrasons pour particules en suspension Ceased WO1997016231A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU38385/95A AU3838595A (en) 1995-10-30 1995-10-30 Apparatus for separating suspended particles by means of ultrasonic waves
PCT/CN1995/000085 WO1997016231A1 (fr) 1995-10-30 1995-10-30 Separateur a ultrasons pour particules en suspension

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN1995/000085 WO1997016231A1 (fr) 1995-10-30 1995-10-30 Separateur a ultrasons pour particules en suspension

Publications (1)

Publication Number Publication Date
WO1997016231A1 true WO1997016231A1 (fr) 1997-05-09

Family

ID=4574944

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN1995/000085 Ceased WO1997016231A1 (fr) 1995-10-30 1995-10-30 Separateur a ultrasons pour particules en suspension

Country Status (2)

Country Link
AU (1) AU3838595A (fr)
WO (1) WO1997016231A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6878288B2 (en) 2002-12-17 2005-04-12 Harold W. Scott System and apparatus for removing dissolved and suspended solids from a fluid stream

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58128181A (ja) * 1982-01-26 1983-07-30 Hitachi Zosen Corp 造水方法
JPS58128180A (ja) * 1982-01-26 1983-07-30 Hitachi Zosen Corp 造水方法
WO1983003596A1 (fr) * 1982-04-14 1983-10-27 Robert Jean Perron Procede et appareil de separation des constituants d'un melange
CN1037463A (zh) * 1987-05-19 1989-11-29 沃尔夫冈·斯塔卡特 从液体中分离物质的方法和实现该方法的装置
CN1069668A (zh) * 1991-08-27 1993-03-10 北京协海医学科技开发公司 一种利用超声分离悬浮颗粒的仪器
WO1993019873A2 (fr) * 1992-04-06 1993-10-14 Mountford Norman D G Traitement par ultrasons de liquides dans certains metaux en fusion
WO1995001214A1 (fr) * 1993-07-02 1995-01-12 University Of British Columbia Filtre acoustique permettant de separer et recycler des particules en suspension
CN1110929A (zh) * 1994-04-28 1995-11-01 王晓庆 一种利用超声分离悬浮颗粒的仪器

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58128181A (ja) * 1982-01-26 1983-07-30 Hitachi Zosen Corp 造水方法
JPS58128180A (ja) * 1982-01-26 1983-07-30 Hitachi Zosen Corp 造水方法
WO1983003596A1 (fr) * 1982-04-14 1983-10-27 Robert Jean Perron Procede et appareil de separation des constituants d'un melange
CN1037463A (zh) * 1987-05-19 1989-11-29 沃尔夫冈·斯塔卡特 从液体中分离物质的方法和实现该方法的装置
CN1069668A (zh) * 1991-08-27 1993-03-10 北京协海医学科技开发公司 一种利用超声分离悬浮颗粒的仪器
WO1993019873A2 (fr) * 1992-04-06 1993-10-14 Mountford Norman D G Traitement par ultrasons de liquides dans certains metaux en fusion
WO1995001214A1 (fr) * 1993-07-02 1995-01-12 University Of British Columbia Filtre acoustique permettant de separer et recycler des particules en suspension
CN1110929A (zh) * 1994-04-28 1995-11-01 王晓庆 一种利用超声分离悬浮颗粒的仪器

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6878288B2 (en) 2002-12-17 2005-04-12 Harold W. Scott System and apparatus for removing dissolved and suspended solids from a fluid stream

Also Published As

Publication number Publication date
AU3838595A (en) 1997-05-22

Similar Documents

Publication Publication Date Title
US4983189A (en) Methods and apparatus for moving and separating materials exhibiting different physical properties
US4759775A (en) Methods and apparatus for moving and separating materials exhibiting different physical properties
US5527460A (en) Multilayered piezoelectric resonator for the separation of suspended particles
US5626767A (en) Acoustic filter for separating and recycling suspended particles
US5711888A (en) Multilayered piezoelectric resonator for the separation of suspended particles
US5164094A (en) Process for the separation of substances from a liquid and device for effecting such a process
US9725690B2 (en) Fluid dynamic sonic separator
JP2012501797A (ja) 流体から気泡を音響学的に増強して除去する方法及び装置
US20060037916A1 (en) Apparatus for separating dispersed particles
US20090137941A1 (en) Method and apparatus for acoustically enhanced removal of bubbles from a fluid
KR20170063882A (ko) 비-유동성 유체 내의 입자의 음향 영동 정화
JPH07504985A (ja) 粒子の集団化方法及び装置
US20030061939A1 (en) Bubble elimination tube with acutely angled transducer horn assembly
CN1091626C (zh) 一种利用超声分离悬浮颗粒的仪器
Hawkes et al. A laminar flow expansion chamber facilitating downstream manipulation of particles concentrated using an ultrasonic standing wave
US6210470B1 (en) Ultrasonic gas separator
JP2001502225A (ja) 液体媒体中の粒子を超音波で操作するための装置及び方法
CN1069668A (zh) 一种利用超声分离悬浮颗粒的仪器
EP0317102A1 (fr) Appareil utilisant les ultrasons pour l'amélioration de la sédimentation pendant la centrifugation
JPH08266891A (ja) 微粒子取扱装置
WO1997016231A1 (fr) Separateur a ultrasons pour particules en suspension
JPH09215942A5 (fr)
US5334136A (en) System for treating blood processed in a cardiopulmonary bypass machine and ultrasound filtration apparatus useful therein
SU394320A1 (ru) Способ осветления суспензий
CN1836769A (zh) 超声液体处理换能方法和装置

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AM AT AU BB BG BR BY CA CH CN CZ DE DK EE ES FI GB GE HU IS JP KE KG KP KR KZ LK LR LT LU LV MD MG MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TT UA UG US UZ VN

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): KE LS MW SD SZ UG AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 95197981.7

Country of ref document: CN

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA