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WO1997016077A1 - Formulations a effet probiotique - Google Patents

Formulations a effet probiotique Download PDF

Info

Publication number
WO1997016077A1
WO1997016077A1 PCT/AT1996/000212 AT9600212W WO9716077A1 WO 1997016077 A1 WO1997016077 A1 WO 1997016077A1 AT 9600212 W AT9600212 W AT 9600212W WO 9716077 A1 WO9716077 A1 WO 9716077A1
Authority
WO
WIPO (PCT)
Prior art keywords
weight
formulation according
chocolate
microorganisms
lactobacillus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/AT1996/000212
Other languages
German (de)
English (en)
Inventor
Wolfgang Kneifel
Josef Raffalt
Helmut Viernstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ed Haas Nahrmittel GmbH
Original Assignee
Ed Haas Nahrmittel GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ed Haas Nahrmittel GmbH filed Critical Ed Haas Nahrmittel GmbH
Priority to AU72655/96A priority Critical patent/AU7265596A/en
Priority to EP96934180A priority patent/EP0858267A1/fr
Priority to AT0067296U priority patent/AT1759U1/de
Publication of WO1997016077A1 publication Critical patent/WO1997016077A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G3/366—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing microorganisms, enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/065—Microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10—Cereal-derived products
    • A23L7/117—Flakes or other shapes of ready-to-eat type; Semi-finished or partly-finished products therefor
    • A23L7/122—Coated, filled, multilayered or hollow ready-to-eat cereals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10—Cereal-derived products
    • A23L7/117—Flakes or other shapes of ready-to-eat type; Semi-finished or partly-finished products therefor
    • A23L7/135—Individual or non-extruded flakes, granules or shapes having similar size, e.g. breakfast cereals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis

Definitions

  • lactic acid bacteria encompasses a category of microorganisms which, due to their human-specific and food-technological properties, have become the focus of scientific interest in recent years and are increasingly being used in probiotic compositions.
  • a particularly preferred probiotic formulation comprises microorganisms of the Lactob species stabilized by lyophilization. acillus acidophilus and chocolate.
  • Another special muesli according to the invention contains:
  • the preparation of the probiotically active formulations according to the invention is preferably carried out in such a way that the microorganisms stabilized by lyophilization are melted into the carrier or, in the case of a liquid or pulpy consistency of the carrier, are suspended in this carrier and then the carrier containing microorganisms is mixed (preferably granulated) with the other components of the formulation and optionally processed and / or packaged.
  • the live bacterial content of Lactobacillus acidophilus was determined on Rogosa agar by plating various dilutions of the starting material. The plates were incubated for 72 hours at 37 ° C. in an anaerobic environment and the colonies obtained were counted.
  • the chocolate muesli with the probiotically active formulations according to the invention was evaluated positively by all testers. It was judged to be sufficient and pleasant tasting of chocolate and was unanimously called "chocolate muesli". A disturbing foreign taste was not found by any of the test subjects.
  • a live germ count after gastric passage which according to the present invention is at least 10 times, preferably at least 100 times, in particular at least 1000 times, higher than that of the pure, dried microorganism preparation readily achievable with the formulations according to the invention.
  • a lyophilisate from Lactobacillus acidophilus (L.acidophilus 74-2, Wiesby) with a guaranteed germ density of 1.0 x 10 11 CFU / g was in an amount of 500 g in a carrier and Hüllstoff ⁇ melt consisting of 2500 g CEBES (Laurian cocoa butter substitute, Aarhus Olie, DK) and 25 g of Ronoxan TM (Hoffmann-LaRoche, CH) were introduced and mixed at a melt temperature of 40 ° C.
  • CEBES Laurian cocoa butter substitute, Aarhus Olie, DK
  • Ronoxan TM Hoffmann-LaRoche, CH
  • Example 6 45.5 kg of dry muesli (from Haas, AT) was coated in a drawer with the formulation obtained in Example 6. This partial batch was made up to a total of 1000 kg with untreated muesli, mixed back and packed.
  • the bacterial counts of Lactobacillus were determined on Rogosa agar Plate casting process determined from various dilution levels of the starting material. The plates were incubated for 72 h at 37 ° C. in an anaerobic environment and the colonies obtained were evaluated.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne une formulation à effet probiotique renfermant des micro-organismes stabilisés par lyophilisation et un substrat alimentaire, lequel permet que les micro-organismes lyophilisés traversent le suc gastrique avec un nombre de germes plus élevé. Les micro-organismes lyophilisés contenus dans le substrat sont fondus. L'invention concerne également leur utilisation comme additifs alimentaires ainsi que comme aliment, notamment du muësli, contenant cette formulation.
PCT/AT1996/000212 1995-11-02 1996-11-04 Formulations a effet probiotique Ceased WO1997016077A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU72655/96A AU7265596A (en) 1995-11-02 1996-11-04 Probiotically acting formulations
EP96934180A EP0858267A1 (fr) 1995-11-02 1996-11-04 Formulations a effet probiotique
AT0067296U AT1759U1 (de) 1996-11-04 1996-11-14 Probiotisch wirksame formulierungen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT180995 1995-11-02
ATA1809/95 1995-11-02

Publications (1)

Publication Number Publication Date
WO1997016077A1 true WO1997016077A1 (fr) 1997-05-09

Family

ID=3521444

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT1996/000212 Ceased WO1997016077A1 (fr) 1995-11-02 1996-11-04 Formulations a effet probiotique

Country Status (3)

Country Link
EP (1) EP0858267A1 (fr)
AU (1) AU7265596A (fr)
WO (1) WO1997016077A1 (fr)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544568B2 (en) 1998-12-15 2003-04-08 Vsl Pharmaceuticals Inc. Symbiotic functional food containing lactic acid bacteria
US6841181B2 (en) 1999-12-22 2005-01-11 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Encapsulated multifunctional biologically active food component, process for its production and its use
WO2006007470A1 (fr) * 2004-07-01 2006-01-19 General Mills, Inc. Micro-organismes encapsules dans du chocolat, produits alimentaires enrobes de chocolat, et methodes de preparation
WO2006007463A1 (fr) * 2004-07-01 2006-01-19 General Mills, Inc. Cultures encapsulees dans des graisses composees, cereales de petit dejeuner recouvertes de ces graisses, et procedes d'elaboration
WO2007081981A3 (fr) * 2006-01-11 2007-12-13 Attune Foods Aliment probiotique, procede de préparation correspondant et régime alimentaire
EP0862863B2 (fr) † 1997-01-09 2008-09-03 Societe Des Produits Nestle S.A. Produit céréalier contenant des probiotiques
WO2010151637A1 (fr) * 2009-06-25 2010-12-29 The Procter & Gamble Company Procédé, d'amélioration de la santé gastro-intestinale au moyen d'une combinaison d'un micro-organisme probiotique et de chocolat
US20110305796A1 (en) * 2008-09-24 2011-12-15 Florence Coulon Method and Equipment for Preparing Cheese or a Cheese Product
US8691303B2 (en) 2009-07-31 2014-04-08 The Iams Company Dusted animal food
US9173423B2 (en) 2009-07-31 2015-11-03 The Iams Company Animal food kibble with electrostatically adhered dusting
US9210945B2 (en) 2009-07-31 2015-12-15 The Iams Company Animal food having low water activity
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
US11154077B2 (en) 2009-07-31 2021-10-26 Mars, Incorporated Process for dusting animal food
US11304428B2 (en) 2015-02-16 2022-04-19 Mars, Incorporated Interlocking kibble
US11388914B2 (en) 2015-04-28 2022-07-19 Mars, Incorporated Process of preparing a wet pet food, wet pet food produced by the process and uses thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1151669A (en) * 1967-04-11 1969-05-14 Werner Buhrdel Improvements relating to the Treatment of Freeze-Dried Bacterial Cultures
FR1584757A (fr) * 1967-06-01 1970-01-02
FR2443247A1 (fr) * 1978-12-05 1980-07-04 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication
DE3738042A1 (de) * 1986-11-12 1988-05-26 Ludwig Schokolade Gmbh Kakaohaltige zubereitung
JPH02200639A (ja) * 1989-01-31 1990-08-08 Shinfusou Seiyaku Kk 脂質被覆細菌製剤
EP0666031A2 (fr) * 1994-02-02 1995-08-09 BARILLA G. e R. F.lli - Società per Azioni Crème à base de graisse anhydre comprenant des lactobacilles viables
EP0704164A2 (fr) * 1994-09-08 1996-04-03 Fuji Oil Co., Ltd. Composition contenant des bactéries lactique

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1151669A (en) * 1967-04-11 1969-05-14 Werner Buhrdel Improvements relating to the Treatment of Freeze-Dried Bacterial Cultures
FR1584757A (fr) * 1967-06-01 1970-01-02
FR2443247A1 (fr) * 1978-12-05 1980-07-04 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication
DE3738042A1 (de) * 1986-11-12 1988-05-26 Ludwig Schokolade Gmbh Kakaohaltige zubereitung
JPH02200639A (ja) * 1989-01-31 1990-08-08 Shinfusou Seiyaku Kk 脂質被覆細菌製剤
EP0666031A2 (fr) * 1994-02-02 1995-08-09 BARILLA G. e R. F.lli - Società per Azioni Crème à base de graisse anhydre comprenant des lactobacilles viables
EP0704164A2 (fr) * 1994-09-08 1996-04-03 Fuji Oil Co., Ltd. Composition contenant des bactéries lactique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 014, no. 485 (C - 0772) 23 October 1990 (1990-10-23) *

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0862863B2 (fr) † 1997-01-09 2008-09-03 Societe Des Produits Nestle S.A. Produit céréalier contenant des probiotiques
US6544568B2 (en) 1998-12-15 2003-04-08 Vsl Pharmaceuticals Inc. Symbiotic functional food containing lactic acid bacteria
US6841181B2 (en) 1999-12-22 2005-01-11 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Encapsulated multifunctional biologically active food component, process for its production and its use
WO2006007470A1 (fr) * 2004-07-01 2006-01-19 General Mills, Inc. Micro-organismes encapsules dans du chocolat, produits alimentaires enrobes de chocolat, et methodes de preparation
WO2006007463A1 (fr) * 2004-07-01 2006-01-19 General Mills, Inc. Cultures encapsulees dans des graisses composees, cereales de petit dejeuner recouvertes de ces graisses, et procedes d'elaboration
WO2007081981A3 (fr) * 2006-01-11 2007-12-13 Attune Foods Aliment probiotique, procede de préparation correspondant et régime alimentaire
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US10709156B2 (en) 2008-07-07 2020-07-14 Mars, Incorporated Pet supplement and methods of making
US20110305796A1 (en) * 2008-09-24 2011-12-15 Florence Coulon Method and Equipment for Preparing Cheese or a Cheese Product
WO2010151637A1 (fr) * 2009-06-25 2010-12-29 The Procter & Gamble Company Procédé, d'amélioration de la santé gastro-intestinale au moyen d'une combinaison d'un micro-organisme probiotique et de chocolat
US8691303B2 (en) 2009-07-31 2014-04-08 The Iams Company Dusted animal food
US9210945B2 (en) 2009-07-31 2015-12-15 The Iams Company Animal food having low water activity
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
US9173423B2 (en) 2009-07-31 2015-11-03 The Iams Company Animal food kibble with electrostatically adhered dusting
US11154077B2 (en) 2009-07-31 2021-10-26 Mars, Incorporated Process for dusting animal food
US11304428B2 (en) 2015-02-16 2022-04-19 Mars, Incorporated Interlocking kibble
US11388914B2 (en) 2015-04-28 2022-07-19 Mars, Incorporated Process of preparing a wet pet food, wet pet food produced by the process and uses thereof

Also Published As

Publication number Publication date
EP0858267A1 (fr) 1998-08-19
AU7265596A (en) 1997-05-22

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