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WO1997012612A1 - Compositions a base de melatonine et d'antalgiques et utilisations - Google Patents

Compositions a base de melatonine et d'antalgiques et utilisations Download PDF

Info

Publication number
WO1997012612A1
WO1997012612A1 PCT/US1995/012369 US9512369W WO9712612A1 WO 1997012612 A1 WO1997012612 A1 WO 1997012612A1 US 9512369 W US9512369 W US 9512369W WO 9712612 A1 WO9712612 A1 WO 9712612A1
Authority
WO
WIPO (PCT)
Prior art keywords
melatonin
sleep
effective dose
administered
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1995/012369
Other languages
English (en)
Inventor
Richard J. Wurtman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indevus Pharmaceuticals Inc
Original Assignee
Interneuron Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interneuron Pharmaceuticals Inc filed Critical Interneuron Pharmaceuticals Inc
Priority to EP95933966A priority Critical patent/EP0854713A4/fr
Priority to PCT/US1995/012369 priority patent/WO1997012612A1/fr
Priority to AU36432/95A priority patent/AU3643295A/en
Priority to JP09514213A priority patent/JP2000509012A/ja
Priority to CA002231557A priority patent/CA2231557A1/fr
Publication of WO1997012612A1 publication Critical patent/WO1997012612A1/fr
Priority to NO981489A priority patent/NO981489L/no
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des compositions à base de mélatonine et d'un (ou plusieurs) antalgique. L'invention concerne également des procédés d'administration de mélatonine et d'un (ou plusieurs) antalgique pour soulager la douleur et induire le sommeil.
PCT/US1995/012369 1995-10-03 1995-10-03 Compositions a base de melatonine et d'antalgiques et utilisations Ceased WO1997012612A1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP95933966A EP0854713A4 (fr) 1995-10-03 1995-10-03 Compositions a base de melatonine et d'antalgiques et utilisations
PCT/US1995/012369 WO1997012612A1 (fr) 1995-10-03 1995-10-03 Compositions a base de melatonine et d'antalgiques et utilisations
AU36432/95A AU3643295A (en) 1995-10-03 1995-10-03 Compositions of melatonin and analgetic agents and methods of use thereof
JP09514213A JP2000509012A (ja) 1995-10-03 1995-10-03 メラトニンおよび鎮痛剤の組成物およびその使用法
CA002231557A CA2231557A1 (fr) 1995-10-03 1995-10-03 Compositions a base de melatonine et d'antalgiques et utilisations
NO981489A NO981489L (no) 1995-10-03 1998-04-02 Blandinger av melatonin og analgetika samt anvendelser derav

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1995/012369 WO1997012612A1 (fr) 1995-10-03 1995-10-03 Compositions a base de melatonine et d'antalgiques et utilisations
CA002231557A CA2231557A1 (fr) 1995-10-03 1995-10-03 Compositions a base de melatonine et d'antalgiques et utilisations

Publications (1)

Publication Number Publication Date
WO1997012612A1 true WO1997012612A1 (fr) 1997-04-10

Family

ID=25680080

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/012369 Ceased WO1997012612A1 (fr) 1995-10-03 1995-10-03 Compositions a base de melatonine et d'antalgiques et utilisations

Country Status (3)

Country Link
EP (1) EP0854713A4 (fr)
CA (1) CA2231557A1 (fr)
WO (1) WO1997012612A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997044045A1 (fr) * 1996-05-20 1997-11-27 Fuisz Technologies Ltd. Melatonine combinee a des analgesiques
WO2014098552A1 (fr) * 2012-12-19 2014-06-26 Cecype Services S. De R.L. De C.V. Composition pharmaceutique qui comprend la combinaison d'un agent antiinflammatoire non stéroïdien, d'un agent adjuvant et d'un analgésique antineuritique, ayant un effet antinociceptif
WO2018130865A1 (fr) * 2017-01-13 2018-07-19 The Hospital For Sick Children Traitement des maux de tête chez les enfants et procédé

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126630B1 (fr) * 1983-05-18 1987-09-16 Monash University Utilisation de melatonine pour la fabrication d'un medicament
US4687763A (en) * 1985-02-25 1987-08-18 Massachusetts Institute Of Technology Composition and method for increasing levels or release of brain serotonin
US5688520A (en) * 1995-03-29 1997-11-18 Minnesota Mining And Manufacturing Company Transmucosal delivery of melatonin for prevention of migraine
FR2741799B1 (fr) * 1995-12-04 1998-01-02 Oreal Utilisation de melatonine dans une composition pour traiter les signes cutanes des etats de fatigue
CA2255838A1 (fr) * 1996-05-20 1997-11-27 Richard C. Fuisz Melatonine combinee a des analgesiques

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, Volume 84, issued 1975, KAMEYAMA et al., "Pharmacological Studies by Successive Drug Administration. I. Effect of Ketoprofen on Inflammation and Spontaneous Motor Activity in Mice", Abstract No. 299; & YAKURI TO CHIRYO, 3(5), pages 828-35. *
CHEMICAL ABSTRACTS, Volume 94, issued 1981, PAVEL et al., "Melatonin, Vasotocin and Rem Sleep in Prepubertal Boys", Abstract No. 171799; & ADV. BIOSCI., 29 (MELATONIN: CURR. STATUS PERSPECT.), pages 343-347. *
CHEMICAL ABSTRACTS, Volume 96, issued 1981, LAKIN et al., "Involvement of the Pineal Gland and Melatonin in Murine Analgesia", Abstract No. 28590; & LIFE SCI., 29 (24), pages 2543-2551. *
See also references of EP0854713A4 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997044045A1 (fr) * 1996-05-20 1997-11-27 Fuisz Technologies Ltd. Melatonine combinee a des analgesiques
WO2014098552A1 (fr) * 2012-12-19 2014-06-26 Cecype Services S. De R.L. De C.V. Composition pharmaceutique qui comprend la combinaison d'un agent antiinflammatoire non stéroïdien, d'un agent adjuvant et d'un analgésique antineuritique, ayant un effet antinociceptif
WO2018130865A1 (fr) * 2017-01-13 2018-07-19 The Hospital For Sick Children Traitement des maux de tête chez les enfants et procédé

Also Published As

Publication number Publication date
EP0854713A4 (fr) 1999-01-07
CA2231557A1 (fr) 1997-04-10
EP0854713A1 (fr) 1998-07-29

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