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WO1997009039A3 - Composition comprising vitamin f - Google Patents

Composition comprising vitamin f Download PDF

Info

Publication number
WO1997009039A3
WO1997009039A3 PCT/US1996/015205 US9615205W WO9709039A3 WO 1997009039 A3 WO1997009039 A3 WO 1997009039A3 US 9615205 W US9615205 W US 9615205W WO 9709039 A3 WO9709039 A3 WO 9709039A3
Authority
WO
WIPO (PCT)
Prior art keywords
rxr
vitamin
composition
acid
9cra
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1996/015205
Other languages
French (fr)
Other versions
WO1997009039A2 (en
Inventor
Cary Weinberger
Sutisak Kitareewan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Priority to AU71160/96A priority Critical patent/AU7116096A/en
Publication of WO1997009039A2 publication Critical patent/WO1997009039A2/en
Anticipated expiration legal-status Critical
Publication of WO1997009039A3 publication Critical patent/WO1997009039A3/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

RXR is a nuclear receptor that plays a central role in cell signaling by pairing with a host of other receptors. Previously, 9-cis-retinoic acid (9cRA) was defined as a potent RXR activator. Here we describe Vitamin F (phytanoic acid), a unique RXR effector identified from organic extracts of bovine serum by following RXR-dependent transcriptional activity, and compositions containing Vitamin F.
PCT/US1996/015205 1995-09-08 1996-09-06 Composition comprising vitamin f Ceased WO1997009039A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU71160/96A AU7116096A (en) 1995-09-08 1996-09-06 Composition comprising vitamin f

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US344395P 1995-09-08 1995-09-08
US60/003,443 1995-09-08

Publications (2)

Publication Number Publication Date
WO1997009039A2 WO1997009039A2 (en) 1997-03-13
WO1997009039A3 true WO1997009039A3 (en) 2001-09-13

Family

ID=21705901

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/015205 Ceased WO1997009039A2 (en) 1995-09-08 1996-09-06 Composition comprising vitamin f

Country Status (2)

Country Link
AU (1) AU7116096A (en)
WO (1) WO1997009039A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1261314A4 (en) * 2000-03-07 2003-06-11 Avon Prod Inc Methods using phytol to improve the appearance of skin and compositions for such methods
US6784207B2 (en) 2000-08-04 2004-08-31 Roche Vitamins Inc. Phytanic acid derivative compositions
DE10253042A1 (en) 2002-11-14 2004-06-03 Wacker-Chemie Gmbh Cosmetic preparation containing a complex of cyclodextrin and vitamin F.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835505A (en) * 1981-08-27 1983-03-02 Masatoshi Takenouchi Mechanism for solar ray inductive device
US5221796A (en) * 1991-02-12 1993-06-22 Fuji Photo Film Co., Ltd. Glycerol derivatives
US5236950A (en) * 1988-02-18 1993-08-17 Toyama Chemical Co., Ltd. Process for hair growth

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835505A (en) * 1981-08-27 1983-03-02 Masatoshi Takenouchi Mechanism for solar ray inductive device
US5236950A (en) * 1988-02-18 1993-08-17 Toyama Chemical Co., Ltd. Process for hair growth
US5221796A (en) * 1991-02-12 1993-06-22 Fuji Photo Film Co., Ltd. Glycerol derivatives

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BARAUD, J. ET AL.: "Rôle de la cha*ne phytyle sur certains symptomes d'avitaminose E chez le poussin.", ARCH. SCI. PHYSIOL, vol. 23, no. 4, 1969, pages 437 - 51, XP000611600 *
BARAUD, J. ET AL.: "Rôle de l'acide phytanique et du phytol chez les poussins en avitaminose e.", C.R.ACAD. SCI. PARIS, SER D, vol. 268, no. 9, 1969, pages 1339 - 41, XP000611606 *
HIDIROGLOU: "Fate of 14C-phytol Administered Orally to Sheep", CAN J. PHYSIOL. PHARM, vol. 50, no. 5, 1972, pages 458 - 62, XP002020042 *
KRYWAWYCH ET AL.: "The Effect of Phytol upon Skeletal Muscle Damage in Vitamin E-Deficient Animals", J. INHER. METAB. DIS., vol. 8, no. suppl 2, 1985, pages 111 - 112, XP002020040 *
WEBER: "Ueber den Mechanismus der Reactivierung der Bersteinsäure-cytochrom-c-Reductase durch die Vitamine E und K.", HELV. CHIM. ACTA, vol. 41, no. 118, 1958, pages 1038 - 1052, XP002020041 *

Also Published As

Publication number Publication date
WO1997009039A2 (en) 1997-03-13
AU7116096A (en) 1997-03-27

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