WO1996039118A1 - Slimming cosmetic compositions - Google Patents

Abstract

The use of a cosmetic gel for controlling a water-retention phenomenon associated with cellulitis is described, which contains a mixture of glycerylpolymethacrylate or glycerylpolyacrylate and of one or more fluidifying solvents chosen from aliphatic alcohols or glycols such as propylene glycol, butylene glycol, polyethylene glycol and ethoxydiglycol.

Description

 Thinning Cosmetic Compositions

"Orange peel" cellulite is the manifestation of a certain metabolic imbalance in the subcutaneous fat cells. She touches

mostly women, at the hips and thighs as well

than the buttocks. It is mainly associated with localized overweight

or not.

The appearance of clinical signs "orange peel" is accompanied

physiologically an increase in the fatty layer, a

multiplication and crosslinking of collagen fibers in connective tissue

(which sometimes leads to painful manifestations: fibrosis) and water retention in these tissues.

While many cosmetic products "slimming" are offered

to combat fat overload (these products claim stimulation of lipolysis, among other things), the particular aspect of retention

of water which participates in the swelling of the integuments and therefore in the macroscopic "cellulite" aspect, has not been much discussed.

In the French patent n ° 9112722 (publication number 2682296), we

have described the use of gels of the "glycerylpoly (meth) acrylate" type, containing glycerin, water and polyacrylate or polymethacrylate

manufactured in such a way that they have the property of absorbing water

surrounding, to act on the water activity of a cosmetic formulation, it is

so of so-called "non-drying" gels. The patented application of these gels concerns their capacity to preserve cosmetic products against microbial contamination by an action

physical (water deprivation) rather than by a biocidal chemical action and

therefore to facilitate the formulation of products without chemical preservatives.

The object of this patent is the discovery that these gels are also capable of exercising this water collection activity, not only within

of a cosmetic product, in a formulation, but also at the level

skin cellulite phenomena. Daily application of the gel by

light massage on the sites affected by cellulite makes it possible to decrease its importance and to decrease the volume of the tissue (highlighted by measuring the perimeter of the thigh, the thickness of the fatty layer by

ultrasound and NMR imaging).

This effect seems to be due to the absorption capacity of water by the gel, which facilitates its elimination from the connective tissue.

The gels can be used pure or partially diluted. An aspect

particular of the patent application concerns the discovery that the dilution

gel with at least one thinning solvent improves the penetration of the gel, and

therefore its effectiveness. Advantageously usable thinning solvents

are chosen from aliphatic alcohols, or propylene glycols

glycol, butylene glycol, polyethylene glycol, ethoxydiglycol. These solvents remove the sticky and "greasy" character of the gel which facilitates its application and promotes acceptance of the method and the product by

the user.

As an example we did the following test:

10 female volunteers chosen on the basis of their state of

apparent cellulite participated in the test. On day D0 the diameter of the thighs was measured using a centimeter. The thickness of the subcutaneous fat layer was measured using ultrasound (ultrasound).

For 28 days, the panelists applied product A to one leg

(upper leg) and product B on the other leg, by a light massage,

twice a day.

After this time, the same parameters (perimeter, thickness of the adipose layer) were measured. Analysis of the results shows that the perimeter of the thighs treated with product A has decreased by 4.5 cm and the thickness of the adipose layer has decreased by 11% (significant at p <0.05).

The variations observed on the legs treated with product B are of

1.5 cm and 3% respectively (statistically insignificant values,

p> 0.05). Product A:

Glycerylpolymethacrylate gel with 66% glycerin 80%

Ethoxydiglycol (TRANSCUTOL ^R ) 20%

Product B:

Carbomer 0.2%

0.2% triethanolamine

Distilled water qs 100.

The slimming and "anti-cellulite" effectiveness of these products can be enhanced

by adding a part of plant extracts with diuretic effect (elderberry, bearberry, orthosiphon, calamus, pilosella, goldenrod, strawberry, horsetail, birch

and others) and on the other hand by the incorporation of lipolytic active agents such as caffeine, theophylline, theobromine, carnitine, plant extracts to

slimming activity (algae, centella asiatica, ivy etc.), these lists being

not exhaustive.

Gel αlvcerylpolv (meth) acrylate / Thinning solvent mixtures can

vary in the proportions from 100/0 to 1/99, preferably between 70/30 and 90/10 and must constitute at least 1% by weight of the finished product. The addition of active ingredients with a diuretic and lipolytic reputation to these

mixtures can be made in the commonly known proportions of

one skilled in the art. These slimming mixtures can be combined in the compositions

cosmetics with any other ingredient usually used in cosmetics: extraction and / or synthetic lipids, gelling and viscous polymers,

surfactants and emulsifiers, water- or fat-soluble active ingredients, extracts

of plants, tissue extracts, marine extracts, liposomes, nano-, micro- or

macroparticles or -capsules.

The mixtures can be used in any suitable galenical form, used in cosmetics or in dermopharmacy, namely gels, O / W and W / O emulsions, milks, lotions, ointments.

Claims

1) Slimming cosmetic compositions with anti-cellulite activity characterized in that they contain the mixture of a gel glycerylpolymethacrylate or glycerylpolyacrylate and at least one fluidizing solvent chosen from aliphatic alcohols or glycols propylene glycol, butylene glycol, polyethylene glycol, ethoxydiglycol to absorb and remove water retained in tissues and that this mixture constitutes at least 1% by weight of the finished product. 2) Cosmetic slimming compositions with anti-cellulite activity according to claim 1, characterized in that the proportions of glycerylpolymethacrylate gel and thinning solvent vary between 100/0 and 1/99, preferably between 70/30 and 90/10. 3) Cosmetic slimming compositions with anti-cellulite activity according to claims 1 to 2, characterized in that they also contain one or more plant extracts with activity diuretic chosen for example from elderberry, bearberry extract, orthosiphon, calamus, pilosella, goldenrod, strawberry, horsetail, birch. 4) Slimming cosmetic compositions with anti-cellulite activity according to claims 1 to 3, characterized in that they additionally contain one or more lipolytic active agents such as caffeine, theophylline, theobromine, carnitine, plant extracts with slimming activity (algae, centella asiatica, ivy ...). 5) Cosmetic slimming compositions with anti-cellulite activity according to claims 1 to 4, characterized in that the gel and solvent mixture is combined in the cosmetic compositions with any other ingredient usually used in cosmetic: extraction and / or synthetic lipids, polymers gelling agents and viscosants, surfactants and emulsifiers, water- or liposoluble active principles, plant extracts, tissue extracts, marine extracts, liposomes, nano-, micro- or macroparticles or -capsules. 6) Slimming cosmetic compositions with anti-cellulite activity according to claims 1 to 5, characterized in that the mixture of gel and solvent is used in any suitable dosage form, used in cosmetics or dermopharmacy, namely gels, O / W and W / O emulsions, milks, lotions, ointments.