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WO1996039030B1 - Sustained release biocidal compositions - Google Patents

Sustained release biocidal compositions

Info

Publication number
WO1996039030B1
WO1996039030B1 PCT/US1996/009179 US9609179W WO9639030B1 WO 1996039030 B1 WO1996039030 B1 WO 1996039030B1 US 9609179 W US9609179 W US 9609179W WO 9639030 B1 WO9639030 B1 WO 9639030B1
Authority
WO
WIPO (PCT)
Prior art keywords
composite
acid
anhydride
group
hydrophilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1996/009179
Other languages
French (fr)
Other versions
WO1996039030A1 (en
Filing date
Publication date
Priority claimed from US08/465,358 external-priority patent/US5650446A/en
Priority to KR1019970700789A priority Critical patent/KR100428227B1/en
Application filed filed Critical
Priority to EP96921314A priority patent/EP0774900B1/en
Priority to JP50156497A priority patent/JP3936740B2/en
Priority to NZ311279A priority patent/NZ311279A/en
Priority to MX9700957A priority patent/MX9700957A/en
Priority to CA002196434A priority patent/CA2196434C/en
Priority to BR9606463A priority patent/BR9606463A/en
Priority to DE69627614T priority patent/DE69627614T2/en
Priority to AU62564/96A priority patent/AU720367B2/en
Priority to HK98114504.3A priority patent/HK1013214B/en
Publication of WO1996039030A1 publication Critical patent/WO1996039030A1/en
Publication of WO1996039030B1 publication Critical patent/WO1996039030B1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Abstract

A composite for retarding bacterial, fungal and viral contamination and mold growth includes a hydrophilic material containing an α-amino ether and a chloride salt, and a hydrophobic material containing an acid releasing agent. The hydrophilic and hydrophobic materials are adjacent and substantially free of water, and the hydrophilic material is capable of releasing chlorine dioxide upon hydrolysis of the acid releasing agent.

Claims

AMENDED CLAIMS
[received by the International Bureau on 4 December 1996 (04.12.96); original claims 3, 15, 22, 23, 31, 41, 42, 44 and 47 amended; new claims 49-55 added; remaining claims unchanged (9 pages)]
1. A composite for retarding bacterial, fungal and viral contamination and mold growth comprising:
a hydrophobic material containing an acid releasing agent and a diluent; and
a hydrophilic material containing chlorite anions, the hydrophilic and hydrophobic materials being adjacent and substantially free of water, the hydrophilic material being capable of releasing chlorine dioxide upon
hydrolysis of "he acid releasing agent.
2. A compositie for retarding bacterial, fungal and viral contamination and mold growth comprising:
a hydrophobic material containing an acid releasing agent; and
a hydrophilic material containing chlorite anions and an amine, an amide, an alcohol, or a compound
containing amino, amido or hydroxyl moieties; the
hydrophilic and hydrophobic materials being adjacent and substantially free of water, and the hydrophilic material being capable of releasing chlorine dioxide upon
hydrolysis of the acid releasing agent.
3. A composite for retarding bacterial, fungal and viral contamination and mold growth comprising:
a hydrophobic material containing an acid releasing agent selected from the group consisting of phosphoric acid, a trimethylsilyl phosphate eater, a dialkyl
phosphate, sulfonic acid, a sulfonic acid chloride, a homopolymer of a mixed inorganic acid anhydride, a phosphosilicaie, a phosphosilane, a copolymer of an organic acid anhydride or a mixed inorganic acid
anhydride with a monomer containing a double bond, and a mixed inorganic acid anhydride containing a phosphorus- oxygen-silicon bond; and a hydrophilic material containing chlorite anions, the hydrophilic and hydrophobic materials being adjacent and substantially free of water, the hydrophilic material being capable of releasing chlorine dioxide upon
hydrolysis of the acid releasing agent.
4. The composite of claim 1, 2 or 3 wherein at least about 1.0 X 10-6 mole chlorms dioxide/cm2 is released from the composite for a period of at least one week.
5. The composite of claim 1, 2 or 3 wherein at least about 1.0 X 10-6 mole chlorine dioxide/cm2 is released from the composite for a period of at least one month.
6 . The composite of claim 1, 2 or 3 wherein at least about 1.0 X 106 mole chlorine dioxide/cm2 is released from the composite for a period of at least six months.
7. The composite of claim 1 wherein the hydrophilic material is selected from the group consisting of an amide, an amine, an alcohol, a compcund containing amino moieties, a compound containing arαido moieties, and a compound containing hydroxyl moieties.
8. The composite of claim 3 wherein the hydrophilic material is selected from the group consisting of an amide, an amine, an alcohol, a compound containing amine moieties, a compound containing amido moieties, and a compound containing hydroxyl moieties.
9. The composite of claim 2, 7 or θ wherein the amide is selected from the group consisting of fcrrrtamide, acrylamide-isopropylacrylamide, a copolymer of formamide and acrylamide-isopropylacrylamide, and a copolymer of acrylamide, isopropylacrylamide or N,N-methylene
bisacrylamide and a primary amine or a secondary amine.
14. The composite of claim 1, 2 or 3 wherein the hydrophilic material includes an iminium chlorite.
15. The composite of claim 1 or 2 wherein the acid releaeing agent: is selected from the group consisting of a carboxyiic acid, an ester, an anhydride, an acyl halide, phosphoric acid, a phosphate ester, a
trimethylsiiyi phosphate ester, a dialkyl phosphate, sulfonic acid, a sulfonic acid ester, a phosphosilicate, a phosphosilane, and a sulfonic acid chloride.
16. The composite of claim 15 wherein the acid releasing agent is an anhydride or phosphate ester blended with or grafted to polypropylene, polyethylene or polystyrene.
17. The composite of claim 15 wherein the trimethylsilyl phosphate ester is (CH3)3SiO2(O) (OR)2 wherein R is a non-hydrogen bonding group, alkyl or aryl.
18. The composite of claim 15 wherein the anhydride is selected from the group consisting of an organic acid anhydride, a mixed organic acid anhydride, a homopolymer of an organic acid anhydride or a mixed inorganic acid anhydride, and a copolymer of an organic acid anhydride or a mixed inorganic acid anhydride with a monomer containing a double bond.
19. The composite of claim 18 wherein the mixed
inorganic acid anhydride contains a phosphorus-oxygen-silicon bond.
20. The composite of claim 18 wherein the anhydride is a copolymer of maleic anhydride, methacrylic anhydride, acetic anhydride, propionic anhydride, or succinic anhydride, and vinyl, styrene or an alxene.
21. The composite of claim 2 wherexn the acid releasing agent is a copolymer of maleic anhydride, methacrylic anhydride, acetic anhydride, prepionic anhydride, or succinic anhydride, and vinyl, styrene or an alkene.
22. The composite of claim 1 wherein the diluent is selected from the group consisting of atactic
polypropylene, hydrocarbon wax, chlorinated wax,
polyethylene wax, polyolefuis, and polyolefm copolymers.
23. The composite of claim 2 or 3 wherein the
hydrophobic material contains a diluent selected from the group consisting of atactic polypropylene, hydrocarbon wax, chlorinated wax, polyethylere wax, polyolefins, and polyolefin copolymers.
24. A dispersion for retarding bacterial, fungal and viral contamination and mold growth comprising:
a hydrophobic phase containing an acid releasing agent; and
a hydrophilic phase containing chloride amone, the hydrophilic and hydrophobic phases being substantially free of water, the hydrophilic phases being capable of releasing chlorine dioxide upon hydrolysis of the acid releasing agent.
25. The dispersion of claim 24 wherein the hydrophobic phase is a continuous phase and the hydrophilic phase is a dispersed phase.
26. The dispersion of claim 24 wherein the hydrophilic phase is a continuous phase and the hydrophobic phase is a dispersed phase,
27. The dispersion of claim 25 or 25 wherein at least about 1.0 X 10-6 mole chlorine dioxide/cm2 is released from the dispersion for a period of at least one week.
2Q. The dispersion of claim 25 or 26 wherein at least about 1.0 X 10-6 mole chlorine dioxide/cm2 is released from the dispersion for a period of at least one month.
29. The dispersion of claim 25 or 25 wherein at lease about 1.0 X 10-6 mole chlorine dioxide/cm2 is released from the dispersion for a period of at least six months.
30. The dispersion of claim 25 or 26 wherein the hydrophilic material is selected from the group
consisting of an amide, an amine, an alcohol, a compound containing amino moieties, a compound containing amide moieties, and a compound containing hydroxyl moieties.
31. The dispersion of claim 25 or 26 wherein the acid releasing agent is selected from the group consisting of a carboxylic acid, an eater, an anhydride, an acyl halide, phosphoric acid, a phosphate ester, a
trimethylsilyl phosphate ester, a dialkyl phosphate, sulfonic acid, a sulfonic acid ester, a phosphosilicate, a phosphosilane, and a sulfonic acid chloride.
32. A composite for retarding bacterial, fungal and viral contamination and mold growth comprising:
a hydrophilic material containing an α-amino ether and a chlorite salt; and
a hydrophobic material containing an acid releasing agent, the hydrophilic and hydrophobic materials being adjacent and substantially free of water, the hydrophilic material being capable of releasing chlorine dioxide upon hydrolysis of the acid releasing agent.
38. The composite of claim 36 wherein the amide is a plasticizer selected from the group consisting of N- methylacetamide, formamide, succinamide, N- ethylacetamide, N-methylformamide, N-ethylformamide, and amido substituted alkylene oxides.
39. The composite of claim 32 wherein the chlorite salt is selected from the group consisting of sodium chlorite, potassium chlorite, calcium chlorite, ammonium chlorite, trialkylammonium chlorite, and quaternary ammonium chlorite.
40. The composite of claim 32 or 33 wherein the
hydrophilic material further includes urea and a
plasticizer selected from the group consisting of N-methylacetamide, formamide, succinamide, N- ethylacetamide, N-methylformamide, N-ethyIformamide, and amido substituted alkylene oxides.
41. The composite of claim 22, 33 or 34 wherein the acid releasing agent is selected from the group consisting of carboxylic acids, esters, anhydrides, acyl halides, phosphoric acid, phosphate esters, trimethylsilyl
phosphate esters, dialkyl phosphates, sulfonic acid, sulfonic acid esters, phoaphosilicates, sulfonic acid chlorides, and phosphoeilanes of glycerol based esters.
42. The composite of claim 41 wherein the hydrophobic material further includes a diluent selected from the group consisting of atactic polypropylene, hydrocarbon wax, chlorinated wax, polyethylene wax, polyolefins, polyesters, and polyolefin copolymers, and a plasticizer selected from the group consisting of formamide and isopropylacrylamide-acrylamide.
43. The composite of claim 32 or 33 wherein the
hydrophobic material comprises between about 10 wt.% and about 100 wt.% of the acid releasing agent, up to about 80 wt.% of a diluent, and up to about 60 wt.%
plasticizer.
44. The composite of claim 43 wherein the acid releasing agent is selected from the group consisting of carboxylic acids, esters, anhydrides, acyl halides, phosphoric acid, phosphate eaters, trimethylsilyl phosphate esters, dialkyl phosphates, sulfonic acid, sulfonic acid esters, phosphosilicates, sulfonic acid chlorides, and
phosphoeilanes of glycerol based esters; the diluent is selected from the group consisting of atactic
polypropylene, hydrocarbon wax, chlorinated wax,
polyethylene wax, polyolefins, polyesters, and polyclefin copolymers; and the plasticizer is selected from the group consisting of formamide and isopropyl acrylamide- acrylamide.
45. The composite of claim 43 wherein the hydrophobic material comprises between about 40 wt.% and about 100 wt. % of the acid releaeing agent, between about 20 wt.% and about 80 wt.% of the diluent, and up to about 20 wt.% of the plasticizer.
46. The composite of claim 33 wherein the base is selected from the group consisting of a metal alkoxide, an ammonium alkoxide, a metal oxide, a. metal acetate, and a metal ion.
47. A hydrophilic composition comprising urea; a
plasticizer selected from the group consisting of N-methylacecamide, formamide, succinamide, N-ethylacetamide, N-methylformamide, N-ethylformamide, and amido substituted alkylene oxides; and a base selected from the group consisting of a metal alkoxide, an
ammonium alkoxide, a trialkylammonium alkoxide, a metal oxide, an acetate, and a metal ion.
48. The hydrophilic composition of claim 47 including between about 25 and about 55 wt.% urea, between about 315 and about 55 wt.% of the plasticizer, and about 10 wt.% of the base.
49. A method of retarding bacterial, fungal, and viral contamination and growth of molds on the surface of a material and/or deodorizing the material comprising:
exposing a surface of a material to a composite that does not release chlorine dioxide in the absence of moisture; and exposing the surface to moisture to release chlorine dioxide from the composite into the atmosphere surrounding the material.
50. The method of claim 49 wherein the material is exposed to chlorine dioxide by a composite that is a portion of a container.
51. The method of claim 50 wherein the container is a containerboard box.
52. The method of claim 49 wherein the composite is comprised of a hydrophobic material containing an acid releasing agent and, optionally a diluent or a
plasticizer, and a hydrophilic material containing chlorite among and an amine, an amide, an alcohol, or a compound containing amino, amido or hydroxyl moieties.
53. A method of retarding bacterial, fungal, and viral contamination and growth of molds on a surface and/or deodorizing the surface comprising: coating a surface of a substrate with a composite that does not release chlorine dioxide in the absence of moisture; and
exposing the coated surface to moisture to release chlorine dioxide from the composite into the atmosphere surrounding the surface.
54. The method of claim 153 wherein the surface is coated with a film comprised of the composite,
55. The method of claim 53 wherein the composite is comprised of a hydrophobic material containing an acid releasing agent and, optionally a diluent or a
plasticizer, and a hydrophilic material containing chlorite anions and an amine, an amide, an alcohol, or a compound containing amine, amido or hydroxyl moieties.
PCT/US1996/009179 1995-06-05 1996-06-04 Sustained release biocidal compositions Ceased WO1996039030A1 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
BR9606463A BR9606463A (en) 1995-06-05 1996-06-04 Biocidal sustained release compositions
CA002196434A CA2196434C (en) 1995-06-05 1996-06-04 Sustained release biocidal compositions
EP96921314A EP0774900B1 (en) 1995-06-05 1996-06-04 Sustained release biocidal compositions
JP50156497A JP3936740B2 (en) 1995-06-05 1996-06-04 Sustained release bactericidal composition
NZ311279A NZ311279A (en) 1995-06-05 1996-06-04 Sustained release biocidal composite comprising hydrophobic material and chlorite-containing hydrophilic material that reacts to release chlorine dioxide
MX9700957A MX9700957A (en) 1995-06-05 1996-06-04 Sustained release biocidal compositions.
DE69627614T DE69627614T2 (en) 1995-06-05 1996-06-04 BIOCID COMPOSITION WITH DELAYED RELEASE
KR1019970700789A KR100428227B1 (en) 1995-06-05 1996-06-04 Sustained release biocidal compositions
HK98114504.3A HK1013214B (en) 1995-06-05 1996-06-04 Sustained release biocidal compositions
AU62564/96A AU720367B2 (en) 1995-06-05 1996-06-04 Sustained release biocidal compositions

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US46203995A 1995-06-05 1995-06-05
US08/462,039 1995-06-05
US08/465,358 US5650446A (en) 1993-02-12 1995-06-05 Sustained release biocidal composition
US08/465,358 1995-06-05

Publications (2)

Publication Number Publication Date
WO1996039030A1 WO1996039030A1 (en) 1996-12-12
WO1996039030B1 true WO1996039030B1 (en) 1997-01-16

Family

ID=27040210

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/009179 Ceased WO1996039030A1 (en) 1995-06-05 1996-06-04 Sustained release biocidal compositions

Country Status (11)

Country Link
EP (1) EP0774900B1 (en)
JP (1) JP3936740B2 (en)
KR (1) KR100428227B1 (en)
AR (1) AR004491A1 (en)
AU (1) AU720367B2 (en)
BR (1) BR9606463A (en)
CA (1) CA2196434C (en)
DE (1) DE69627614T2 (en)
MY (1) MY113805A (en)
NZ (1) NZ311279A (en)
WO (1) WO1996039030A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046243A (en) * 1993-02-12 2000-04-04 Bernard Technologies, Inc. Compositions for sustained release of a gas
MY112836A (en) * 1995-06-05 2001-09-29 Bernard Tech Inc Sustained release biocidal compositions and their uses
US6120731A (en) * 1999-02-18 2000-09-19 Alcide Corporation Frozen chlorine dioxide-containing composition and methods related thereto
WO2017041038A1 (en) 2015-09-03 2017-03-09 The Administrators Of The Tulane Educational Fund Compositions and methods for multipurpose disinfection and sterilization solutions
CN112512834A (en) * 2019-05-10 2021-03-16 住友橡胶工业株式会社 Plasticizer, composition and tire
DE102023121242A1 (en) 2023-08-09 2025-02-13 Khs Gmbh Preform, container made from a preform, separate container part, plant for producing and/or treating the same and method for sterilizing

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4891216A (en) * 1987-04-14 1990-01-02 Alcide Corporation Disinfecting compositions and methods therefor
US4829129A (en) * 1987-05-29 1989-05-09 International Dioxcide, Inc. Reaction product of polymer with chlorine dioxide
US5360609A (en) * 1993-02-12 1994-11-01 Southwest Research Institute Chlorine dioxide generating polymer packaging films
ES2139709T3 (en) * 1993-02-12 2000-02-16 Southwest Res Inst BIOCIDAL POLYMERIC COMPOSITION AND PROCEDURE FOR ITS PREPARATION.

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