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WO1996013225A3 - Assays, devices and kits for determining male fertility - Google Patents

Assays, devices and kits for determining male fertility Download PDF

Info

Publication number
WO1996013225A3
WO1996013225A3 PCT/US1995/014083 US9514083W WO9613225A3 WO 1996013225 A3 WO1996013225 A3 WO 1996013225A3 US 9514083 W US9514083 W US 9514083W WO 9613225 A3 WO9613225 A3 WO 9613225A3
Authority
WO
WIPO (PCT)
Prior art keywords
kits
assays
devices
male fertility
determining male
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1995/014083
Other languages
French (fr)
Other versions
WO1996013225A2 (en
WO1996013225A9 (en
Inventor
Juan G Alvarez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beth Israel Deaconess Medical Center Inc
Original Assignee
Beth Israel Deaconess Medical Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/332,825 external-priority patent/US5895749A/en
Application filed by Beth Israel Deaconess Medical Center Inc filed Critical Beth Israel Deaconess Medical Center Inc
Priority to EP95939003A priority Critical patent/EP0789538A1/en
Priority to AU40182/95A priority patent/AU4018295A/en
Priority to JP8514826A priority patent/JPH11514204A/en
Publication of WO1996013225A2 publication Critical patent/WO1996013225A2/en
Publication of WO1996013225A9 publication Critical patent/WO1996013225A9/en
Publication of WO1996013225A3 publication Critical patent/WO1996013225A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/367—Infertility, e.g. sperm disorder, ovulatory dysfunction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Assays, devices and kits for identifying sperm samples with high pregnancy potential (e.g. for use in an assisted reproductive technology) or sperm samples with low pregnancy potential (e.g. for identifying potentially infertile males or for evaluating the effectiveness of a male contraception means) are disclosed.
PCT/US1995/014083 1994-10-31 1995-10-31 Assays, devices and kits for determining male fertility Ceased WO1996013225A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP95939003A EP0789538A1 (en) 1994-10-31 1995-10-31 Assays, devices and kits for determining male fertility
AU40182/95A AU4018295A (en) 1994-10-31 1995-10-31 Assays, devices and kits for determining male fertility
JP8514826A JPH11514204A (en) 1994-10-31 1995-10-31 Tests, equipment and instruments for determining male fertility

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33282694A 1994-10-31 1994-10-31
US08/332,826 1994-10-31
US08/332,825 US5895749A (en) 1994-10-31 1994-10-31 Male fertility and contraception home test kits
US08/332,825 1994-10-31

Publications (3)

Publication Number Publication Date
WO1996013225A2 WO1996013225A2 (en) 1996-05-09
WO1996013225A9 WO1996013225A9 (en) 1996-08-08
WO1996013225A3 true WO1996013225A3 (en) 1997-01-09

Family

ID=26988407

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/014083 Ceased WO1996013225A2 (en) 1994-10-31 1995-10-31 Assays, devices and kits for determining male fertility

Country Status (5)

Country Link
EP (1) EP0789538A1 (en)
JP (1) JPH11514204A (en)
AU (1) AU4018295A (en)
CA (1) CA2203828A1 (en)
WO (1) WO1996013225A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935800A (en) * 1994-10-31 1999-08-10 Beth Israel Deaconess Medical Center Assays and kits for determining male fertility
US5866354A (en) * 1996-12-16 1999-02-02 The State Of Oregon Acting By And Through The State Of Board Of Higher Education On Behalf Of Oregon State University Method for measuring mobility of sperm
WO1999066331A1 (en) * 1998-06-17 1999-12-23 Genosis, Inc. Method and kit for the detection of male infertility
GB9817795D0 (en) * 1998-08-14 1998-10-14 Genosis Inc A method and device for separation and detection of spermatozoa in a sample
US6884601B1 (en) * 1999-03-09 2005-04-26 Leopold Flohe Method to detect fertilization potential of sperm
EP1159445A1 (en) * 1999-03-09 2001-12-05 Flohé, Leopold Method to search for male antifertility drugs based on phgpx activity determination
DE102007045935B4 (en) 2007-09-25 2015-02-12 Philipps-Universität Marburg fertility test
US12065698B2 (en) 2009-10-02 2024-08-20 Thermo Fisher Scientific Baltics Uab Sample processing apparatus and method
FI20096013A7 (en) 2009-10-02 2011-04-03 Finnzymes Oy Method for preparing a reaction mixture and related products
EP2388588B1 (en) * 2010-05-18 2013-10-30 Justus-Liebig-Universität Gießen Method and quick test for determining the fertility of sperms
WO2016085997A2 (en) 2014-11-25 2016-06-02 Aytu Bioscience, Inc. Determination of fertility potential from the oxidation-reduction potential of a biological sample
KR101879496B1 (en) * 2016-07-13 2018-07-17 경북대학교 산학협력단 Composition for identification of mammal testicular cell comprising ACRBP antibody
CN107290547A (en) * 2017-08-07 2017-10-24 广州市微米生物科技有限公司 A kind of infertile quick detection kit and preparation method thereof
CN120629562A (en) * 2025-08-12 2025-09-12 复旦大学附属妇产科医院 Colloidal gold kit, preparation method and application thereof in rapid detection of sperm motility

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4007087A (en) * 1975-10-17 1977-02-08 Gametrics Limited Sperm fractionation and storage
US4009260A (en) * 1973-04-19 1977-02-22 Schering Aktiengesellschaft Fractionation of sperm
FR2539628A1 (en) * 1983-01-25 1984-07-27 Fondation Rech Hormonologie Method for separating motile cells, especially motile spermatozoa, as well as a device for implementing this method
WO1987002382A1 (en) * 1985-10-18 1987-04-23 Pharmacia Ab Process for separating motile sperm cells in vitro, fertilization method and penetration medium for sperm cells
FR2709250A1 (en) * 1993-08-23 1995-03-03 Ccd Laboratoire Device for selecting spermatozoa

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4009260A (en) * 1973-04-19 1977-02-22 Schering Aktiengesellschaft Fractionation of sperm
US4007087A (en) * 1975-10-17 1977-02-08 Gametrics Limited Sperm fractionation and storage
FR2539628A1 (en) * 1983-01-25 1984-07-27 Fondation Rech Hormonologie Method for separating motile cells, especially motile spermatozoa, as well as a device for implementing this method
WO1987002382A1 (en) * 1985-10-18 1987-04-23 Pharmacia Ab Process for separating motile sperm cells in vitro, fertilization method and penetration medium for sperm cells
FR2709250A1 (en) * 1993-08-23 1995-03-03 Ccd Laboratoire Device for selecting spermatozoa

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ANDROLOGIA (1986), 18(5), 548-52 CODEN: ANDRDQ;ISSN: 0303-4569 *
CHEMICAL ABSTRACTS, vol. 106, no. 3, 19 January 1987, Columbus, Ohio, US; abstract no. 16572, SCHILL, W. B.: "Indications for determination of acrosin activity" *
CHEMICAL ABSTRACTS, vol. 119, no. 11, 13 September 1993, Columbus, Ohio, US; abstract no. 114355, AITKEN, R. J. ET AL: "Relationship between iron - catalyzed lipid peroxidation potential and human sperm function" *
CHEMICAL ABSTRACTS, vol. 87, no. 25, 19 December 1977, Columbus, Ohio, US; abstract no. 198648, CRABBE, M. J. C.: "The development of a qualitative assay for male infertility from a study of enzymes in human semen" *
J. REPROD. FERTIL. (1977), 51(1), 73-6 CODEN: JRPFA4 *
J. REPROD. FERTIL. (1993), 98(1), 257-65 CODEN: JRPFA4;ISSN: 0022-4251 *

Also Published As

Publication number Publication date
WO1996013225A2 (en) 1996-05-09
JPH11514204A (en) 1999-12-07
AU4018295A (en) 1996-05-23
CA2203828A1 (en) 1996-05-09
EP0789538A1 (en) 1997-08-20

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