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WO1996006639A3 - Novel drugs containing chelate-forming agents - Google Patents

Novel drugs containing chelate-forming agents Download PDF

Info

Publication number
WO1996006639A3
WO1996006639A3 PCT/EP1995/003426 EP9503426W WO9606639A3 WO 1996006639 A3 WO1996006639 A3 WO 1996006639A3 EP 9503426 W EP9503426 W EP 9503426W WO 9606639 A3 WO9606639 A3 WO 9606639A3
Authority
WO
WIPO (PCT)
Prior art keywords
novel drugs
forming agents
drugs containing
containing chelate
bivalent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1995/003426
Other languages
German (de)
French (fr)
Other versions
WO1996006639A2 (en
Inventor
Serban Al Bacanu
Iulian Ionescu
Sorin Sarzea
Stefan Teodor Tomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sicomed SA
Original Assignee
Sicomed SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sicomed SA filed Critical Sicomed SA
Priority to AU35194/95A priority Critical patent/AU3519495A/en
Publication of WO1996006639A2 publication Critical patent/WO1996006639A2/en
Publication of WO1996006639A3 publication Critical patent/WO1996006639A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/30—Copper compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/315—Zinc compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention concerns novel drugs which contain chelate-forming agents and essential amino acids or their derivatives which are optionally complexed with bivalent metal ions. The novel drugs further contain bivalent elements or compounds of bivalent elements.
PCT/EP1995/003426 1994-09-01 1995-08-31 Novel drugs containing chelate-forming agents Ceased WO1996006639A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU35194/95A AU3519495A (en) 1994-09-01 1995-08-31 Novel drugs containing chelate-forming agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19944431175 DE4431175A1 (en) 1994-09-01 1994-09-01 New drugs containing chelating agents
DEP4431175.3 1994-09-01

Publications (2)

Publication Number Publication Date
WO1996006639A2 WO1996006639A2 (en) 1996-03-07
WO1996006639A3 true WO1996006639A3 (en) 1996-07-25

Family

ID=6527188

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1995/003426 Ceased WO1996006639A2 (en) 1994-09-01 1995-08-31 Novel drugs containing chelate-forming agents

Country Status (3)

Country Link
AU (1) AU3519495A (en)
DE (1) DE4431175A1 (en)
WO (1) WO1996006639A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997009976A2 (en) * 1995-09-01 1997-03-20 Washington University Method of reducing neurotoxic injury with zinc chelators
DE19641197C2 (en) * 1996-09-24 1999-02-18 Schering Ag Ion pairs and their use as contrast agents
CA2277911C (en) * 1997-01-13 2010-09-14 Emory University Compounds and their combinations for the treatment of influenza infection
DE19735126C1 (en) * 1997-08-13 1999-01-21 Infectopharm Arzneimittel Und Process for the preparation of an oral composition containing a zinc compound and its use for the treatment of colds
US6103748A (en) * 1998-06-19 2000-08-15 Bryan; Thomas B. Method of treating an autoimmune disorder
ES2216709B1 (en) * 2003-04-08 2005-08-01 Mercedes Nubia Perez De Cabrales PHARMACEUTICAL COMPOSITION TO TREAT ZOSTER HERPES.
RU2008106419A (en) * 2008-02-21 2009-08-27 Закрытое акционерное общество "Ива фарм" (RU) MEDICINES BASED ON OLIGO-NUCLEAR COORDINATION COMPOUNDS OF D-METALS, METHOD FOR THERAPEUTIC INFLUENCE ON THE PATIENT'S ORGANISM AND METHOD FOR IMPROVING THERAPEUTIC EFFICIENCY OF PHARMACOLOGY
MX2018002985A (en) * 2018-03-09 2019-09-10 Inst Tecnologico Jose Mario Molina Pasquel Y Henriquez Bimetal complexes with divalent cations with an inhibiting effect on hsv replication.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2827478A1 (en) * 1978-06-22 1980-01-17 Jozsef Dr Beres Medicaments for tumour therapy - contg. trace elements, glycine, glycerol, ascorbic acid, tetra:halo-fluorescein, EDTA and tartrate
WO1983002893A1 (en) * 1982-02-23 1983-09-01 Dinu, Romulus, Constantin Medicinal composition for the treatment of certain neuroviroses
WO1992015329A1 (en) * 1991-02-28 1992-09-17 The United States Of America, Represented By The Secretary, United States Department Of Commerce Methods and pharmaceutical compositions for inhibiting protease from human immunodeficiency virus
WO1994022438A1 (en) * 1993-03-26 1994-10-13 Constantin Romulus Dinu Pharmaceutical composition for the treatment of certain viruses and autoimmune diseases and the procedure of its preparation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2827478A1 (en) * 1978-06-22 1980-01-17 Jozsef Dr Beres Medicaments for tumour therapy - contg. trace elements, glycine, glycerol, ascorbic acid, tetra:halo-fluorescein, EDTA and tartrate
WO1983002893A1 (en) * 1982-02-23 1983-09-01 Dinu, Romulus, Constantin Medicinal composition for the treatment of certain neuroviroses
WO1992015329A1 (en) * 1991-02-28 1992-09-17 The United States Of America, Represented By The Secretary, United States Department Of Commerce Methods and pharmaceutical compositions for inhibiting protease from human immunodeficiency virus
WO1994022438A1 (en) * 1993-03-26 1994-10-13 Constantin Romulus Dinu Pharmaceutical composition for the treatment of certain viruses and autoimmune diseases and the procedure of its preparation

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DINU R ET AL: "Chelatotherapy in multiple sclerosis. Open preliminary study of a new therapeutical principle applied in multiple sclerosis--public health topic.", SANTE PUBLIQUE (BUCUR), 1985, 28 (1) P3-30, ROMANIA, XP002002402 *
DINU R ET AL: "Herpes zoster and herpes simplex--public health matter;chelatotherapy in these acute neuroviroses.", SANTE PUBLIQUE (BUCUR), 1984, 27 (2) P99-114, ROMANIA, XP002002401 *
DINU R ET AL: "Rodilemid therapy in peripheral palsy: a clinical and electrophysiological study.", NEUROL PSYCHIATR (BUCUR), OCT-DEC 1986, 24 (4) P263-8, ROMANIA, XP002002404 *
R. DINU ET AL.: "Chelatotherapy with Rodilemid in some acute neuroviroses and multiple sclerosis", NEUROL. PSYCHIATR. REV. ROUM. MED., vol. 21, no. 3, 1983, pages 307 - 308, XP002002403 *
ST. AGRIGOROAEI ET AL.: "Specific action of some biosynthesis products upon the body's defence capacity", REV. ROUM. BIOL. SER. BIOL. ANIM., vol. 34, no. 2, 1989, pages 129 - 132, XP002002405 *

Also Published As

Publication number Publication date
AU3519495A (en) 1996-03-22
WO1996006639A2 (en) 1996-03-07
DE4431175A1 (en) 1996-04-11

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