[go: up one dir, main page]

WO1995033049A3 - FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS - Google Patents

FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS Download PDF

Info

Publication number
WO1995033049A3
WO1995033049A3 PCT/FR1995/000701 FR9500701W WO9533049A3 WO 1995033049 A3 WO1995033049 A3 WO 1995033049A3 FR 9500701 W FR9500701 W FR 9500701W WO 9533049 A3 WO9533049 A3 WO 9533049A3
Authority
WO
WIPO (PCT)
Prior art keywords
tbp2
neisseria meningitidis
fragments
transferrine
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR1995/000701
Other languages
English (en)
Other versions
WO1995033049A2 (fr
Inventor
Marie-Jose Bernadette J Millet
Ling Lissolo
Veronique Mazarin
Michele Legrain
Eric Jacobs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Sanofi Pasteur SA
Original Assignee
Transgene SA
Pasteur Merieux Serum et Vaccines SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene SA, Pasteur Merieux Serum et Vaccines SA filed Critical Transgene SA
Priority to FI960428A priority Critical patent/FI960428L/fi
Priority to HU9600210A priority patent/HU220116B/hu
Priority to EP95921860A priority patent/EP0720653A1/fr
Priority to JP8500434A priority patent/JPH09501059A/ja
Priority to AU26757/95A priority patent/AU706090B2/en
Publication of WO1995033049A2 publication Critical patent/WO1995033049A2/fr
Publication of WO1995033049A3 publication Critical patent/WO1995033049A3/fr
Priority to NO960332A priority patent/NO960332L/no
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention a pour objet un polypeptide ayant une séquence d'acides aminés qui dérive de celle de la sous-unité Tbp2 du récepteur transferrine d'une souche de Neisseria meningitidis de type IM2169 ou IM2394 dont les premier, deuxième et troisième domaines sont définis par alignement au maximum d'homologie, sur la séquence de la sous-unité Tbp2 de la souche de référence respective, IM2169 ou IM2394, notamment par délétion totale ou partielle d'au moins un domaine de ladite sous-unité Tbp2 de type IM2169 ou IM2394, à condition que le premier et le deuxième domaine ne soient pas simultanément et totalement délétés.
PCT/FR1995/000701 1994-05-31 1995-05-30 FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS Ceased WO1995033049A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FI960428A FI960428L (fi) 1994-05-31 1995-05-30 Meningokokin reseptoritransferriinin Tbp2-osia
HU9600210A HU220116B (hu) 1994-05-31 1995-05-30 A Neisseria meningitidis transzferin-receptorának Tbp2-fragmentumai
EP95921860A EP0720653A1 (fr) 1994-05-31 1995-05-30 FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS
JP8500434A JPH09501059A (ja) 1994-05-31 1995-05-30 髄膜炎菌のトランスフェリン受容体のＴｂｐ２断片
AU26757/95A AU706090B2 (en) 1994-05-31 1995-05-30 Tbp2 fragments of the transferrine receptor of neisseria meningitidis
NO960332A NO960332L (no) 1994-05-31 1996-01-26 Tbp2 fragmenter av transferrinreseptoren av neisseria meningitidis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9406594A FR2720408B1 (fr) 1994-05-31 1994-05-31 Fragments Tbp2 de Neisseria meningitidis.
FR94/06594 1994-05-31

Publications (2)

Publication Number Publication Date
WO1995033049A2 WO1995033049A2 (fr) 1995-12-07
WO1995033049A3 true WO1995033049A3 (fr) 1996-01-04

Family

ID=9463680

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1995/000701 Ceased WO1995033049A2 (fr) 1994-05-31 1995-05-30 FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS

Country Status (9)

Country Link
EP (1) EP0720653A1 (fr)
JP (1) JPH09501059A (fr)
AU (1) AU706090B2 (fr)
CA (1) CA2167936A1 (fr)
FI (1) FI960428L (fr)
FR (1) FR2720408B1 (fr)
HU (1) HU220116B (fr)
NO (1) NO960332L (fr)
WO (1) WO1995033049A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2739624B1 (fr) * 1995-10-10 1997-12-05 Pasteur Merieux Serums Vacc Nouvelle sous-unite tbp2 de neisseria meningitidis
US6090576A (en) * 1996-03-08 2000-07-18 Connaught Laboratories Limited DNA encoding a transferrin receptor of Moraxella
US6440701B1 (en) 1996-03-08 2002-08-27 Aventis Pasteur Limited Transferrin receptor genes of Moraxella
FR2767060B1 (fr) * 1997-08-07 2000-02-11 Pasteur Merieux Serums Vacc Vaccin meningocoque comportant la valence de souche bz83
PL194800B1 (pl) * 1997-08-15 2007-07-31 Stw Technology Foundation Polinukleotydy kodujące białko LbpB Neisseria meningitidis, jego fragment lub białko o określonej identyczności z białkiem LbpB Neisseria meningitidis, komórka gospodarza zawierająca taki polinukleotyd i sposób jej wytwarzania, sposoby wytwarzania rekombinowanego polipeptydu LbpB i pęcherzyka zewnątrzbłonowego zawierającego zrekombinowny LbpB, nielipidowany polipeptyd LbpB z Neisseria meningitidis, rekombinowny polipeptyd oraz polipeptyd LbpB z Neisseria meningitidis, jego fragment oraz swoiste immunologiczne przeciwciało wobec polipeptydu LbpB z Neiss
EP2210945B1 (fr) 1998-01-14 2013-06-26 Novartis Vaccines and Diagnostics S.r.l. Antigènes de Neisseria meningitidis
EP2261355A3 (fr) 1998-05-01 2012-01-11 Novartis Vaccines and Diagnostics, Inc. Antigènes de Neisseria meningitidis et compositions
FR2785293B1 (fr) * 1998-10-30 2002-07-05 Pasteur Merieux Serums Vacc Acides nucleiques et polypeptides specifiques des souches pathogenes du genre neisseria
US6391316B1 (en) 1999-03-10 2002-05-21 University Of Saskatchewan Vaccine compositions comprising Haemophilus somnus transferrin-binding proteins and methods of use
US7241449B1 (en) 1999-04-12 2007-07-10 Aventis Pasteur Limited Transferrin receptor genes of moraxella
AU4309600A (en) 1999-04-30 2000-11-17 Chiron S.R.L. Conserved neisserial antigens
EP2270172B1 (fr) 1999-05-19 2016-01-13 GlaxoSmithKline Biologicals SA Compositions à base de combinaisons de Neisseria
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
PT1790660E (pt) 2000-02-28 2012-09-17 Novartis Vaccines & Diagnostic Expressão heteróloga de proteínas de neisseria
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
AU2003274511B2 (en) 2002-10-11 2009-06-04 Glaxosmithkline Biologicals S.A. Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
CA2810971C (fr) 2010-09-10 2020-11-03 Novartis Ag Developpements apportes a des vesicules membranaires externes meningococciques
EP2861247B1 (fr) 2012-06-14 2020-12-09 GlaxoSmithKline Biologicals SA Vaccins contre le méningocoque de sérogroupe x

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006861A1 (fr) * 1991-10-03 1993-04-15 Pasteur Merieux Serums Et Vaccins S.A. VACCIN CONTRE LES INFECTIONS A $i(NEISSERIA MENINGITIDIS)
WO1993007172A1 (fr) * 1991-10-03 1993-04-15 Pasteur Merieux Serums Et Vaccins S.A. Vaccin de sous-unite contre les infections a neisseriameningitidis et sous-unites correspondantes a l'etat purifie
FR2692592A1 (fr) * 1992-06-19 1993-12-24 Pasteur Merieux Serums Vacc Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant.
WO1994005703A1 (fr) * 1992-08-31 1994-03-17 Global Tek, Inc. Anticorps monoclonal contre la proteine de la bacterie neisseria meningitidis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006861A1 (fr) * 1991-10-03 1993-04-15 Pasteur Merieux Serums Et Vaccins S.A. VACCIN CONTRE LES INFECTIONS A $i(NEISSERIA MENINGITIDIS)
WO1993007172A1 (fr) * 1991-10-03 1993-04-15 Pasteur Merieux Serums Et Vaccins S.A. Vaccin de sous-unite contre les infections a neisseriameningitidis et sous-unites correspondantes a l'etat purifie
FR2692592A1 (fr) * 1992-06-19 1993-12-24 Pasteur Merieux Serums Vacc Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant.
WO1994005703A1 (fr) * 1992-08-31 1994-03-17 Global Tek, Inc. Anticorps monoclonal contre la proteine de la bacterie neisseria meningitidis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LEGRAIN, M. ET AL.;: "Cloning and characterization of Neisseria meneingitidis genes encoding the transferrin-binding proteins Tbp1 and Tbp2", GENE, vol. 130, AMSTERDAM NL, pages 73 - 80 *
STEVENSON, P. ET AL.;: "Common antigenic domains in Transferrin-Binding protein 2 of Neisseria meningitidis, Neisseria gonorrhoeae and Haemphilus influenzae Type b", INFECTION AND IMMUNITY, vol. 60, no. 6, WASHINGTON US, pages 2391 - 2396 *

Also Published As

Publication number Publication date
FI960428A7 (fi) 1996-03-28
JPH09501059A (ja) 1997-02-04
FR2720408B1 (fr) 1996-08-14
HU220116B (hu) 2001-11-28
NO960332D0 (no) 1996-01-26
AU2675795A (en) 1995-12-21
HUT75992A (en) 1997-05-28
EP0720653A1 (fr) 1996-07-10
FI960428L (fi) 1996-03-28
AU706090B2 (en) 1999-06-10
FI960428A0 (fi) 1996-01-30
WO1995033049A2 (fr) 1995-12-07
FR2720408A1 (fr) 1995-12-01
CA2167936A1 (fr) 1995-12-07
NO960332L (no) 1996-03-21

Similar Documents

Publication Publication Date Title
WO1995033049A3 (fr) FRAGMENTS Tbp2 DU RECEPTEUR TRANSFERRINE DE NEISSERIA MENINGITIDIS
WO1995030750A3 (fr) Fractions polypeptidiques solubles de la proteine lag-3; procede de production; composition therapeutique; anticorps anti-idiotype
NZ508366A (en) Neisseria meningitidis antigens and compositions
EP1231218A3 (fr) Peptide coupe-faim, ses compositions et son utilisation
WO1999024578A3 (fr) Antigenes de neisseria
WO1999036544A3 (fr) Antigenes du $i(neisseria meningitidis)
AU5197896A (en) Recombinant obese (Ob) proteins
NO990465D0 (no) Polypeptider som har en enkel, kovalent bundet N-terminal vannoppl°selig polymer
NO953901L (no) Rekombinante alfavirus-vektorer
CA2166691A1 (fr) Transposon tn5401 de bacillus thuringiensis et son utilisation dans un systeme de recombinaison specifique au site pour l'obtention d'une souche de bacillus thuringiensis
AU693289B2 (en) Denatured low-density lipoprotein receptor
WO1999020747A3 (fr) NOUVELLE KINASE HUMAINE POINT DE CONTROLE, hCDS1, COMPOSITIONS ET METHODES ASSOCIEES
AU7406694A (en) Novel b. burgdorferi polypeptides
AU5789499A (en) (neisseria meningitidis) polypeptide, nucleic acid sequence and uses thereof
EP0886897A4 (fr) Resonateur optique comportant des elements optiques en spirale
DE59801230D1 (de) Endothelin-rezeptorantagonisten zur bekämpfung von hyperlipidämie
WO1996017059A3 (fr) Recepteur du domaine de fixation cellulaire de la thrombospondine
AU7690896A (en) Recombinant polypeptide based on the primary sequence of the invariant chain with at least one primary sequence of a specific t-cell epitope or a protein derivative and nucleic acids coding for this recombinant polypeptide
NO970113L (no) Kollagenbindende protein eller polypeptid
EP1090994A3 (fr) Immunogènes à séquences peptidiques répétitives
IL139604A0 (en) Novel peptides
AU6643894A (en) Elastic membrane
AU3929589A (en) Human papilloma virus type 57, the dna thereof and the proteins encoded thereby
AU8751298A (en) Replication-competent recombinant sabin type 1 strain of poliovirus
AU4174596A (en) Peptides endowed with antiinflammatory activity

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU CA FI HU JP NO US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

WWE Wipo information: entry into national phase

Ref document number: 2167936

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 1995921860

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 960428

Country of ref document: FI

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AU CA FI HU JP NO US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

ENP Entry into the national phase

Ref document number: 1996 591447

Country of ref document: US

Date of ref document: 19960418

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 1995921860

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1995921860

Country of ref document: EP