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WO1994011518A3 - Methods for converting a, ab, and b blood types to o blood type - Google Patents

Methods for converting a, ab, and b blood types to o blood type Download PDF

Info

Publication number
WO1994011518A3
WO1994011518A3 PCT/US1993/010794 US9310794W WO9411518A3 WO 1994011518 A3 WO1994011518 A3 WO 1994011518A3 US 9310794 W US9310794 W US 9310794W WO 9411518 A3 WO9411518 A3 WO 9411518A3
Authority
WO
WIPO (PCT)
Prior art keywords
acetylgalactosaminidase
blood
converting
methods
types
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1993/010794
Other languages
French (fr)
Other versions
WO1994011518A2 (en
Inventor
Randy M Berka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danisco US Inc
Original Assignee
Genencor International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor International Inc filed Critical Genencor International Inc
Priority to EP94901346A priority Critical patent/EP0668920A1/en
Priority to JP6512285A priority patent/JPH08503137A/en
Publication of WO1994011518A2 publication Critical patent/WO1994011518A2/en
Publication of WO1994011518A3 publication Critical patent/WO1994011518A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01049—Alpha-N-acetylgalactosaminidase (3.2.1.49)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A process for producing α-N-acetylgalactosaminidase by expressing a DNA sequence derived from human placenta encoding α-N-acetylgalactosaminidase in a recombinant host microorganism transformed with an expression vector containing DNA sequence and isolating transformants having α-N-acetylgalactosaminidase expression. The isolated transformants are then cultured and α-N-acetylgalactosaminidase is purified from the culture media. The recombinantly produced α-N-acetylgalactosaminidase is used to convert A, B and AB blood types into O blood type.
PCT/US1993/010794 1992-11-18 1993-11-08 Methods for converting a, ab, and b blood types to o blood type Ceased WO1994011518A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP94901346A EP0668920A1 (en) 1992-11-18 1993-11-08 Methods for converting a, ab, and b blood types to o blood type
JP6512285A JPH08503137A (en) 1992-11-18 1993-11-08 Method for converting A, AB and B blood to O blood

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97794592A 1992-11-18 1992-11-18
US07/977,945 1992-11-18

Publications (2)

Publication Number Publication Date
WO1994011518A2 WO1994011518A2 (en) 1994-05-26
WO1994011518A3 true WO1994011518A3 (en) 1994-11-10

Family

ID=25525671

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/010794 Ceased WO1994011518A2 (en) 1992-11-18 1993-11-08 Methods for converting a, ab, and b blood types to o blood type

Country Status (4)

Country Link
EP (1) EP0668920A1 (en)
JP (1) JPH08503137A (en)
CA (1) CA2149641A1 (en)
WO (1) WO1994011518A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2159083C (en) * 1993-03-26 2002-07-02 Alex Zhu Recombinant .alpha.-n-acetylgalactosaminidase enzyme and cdna encoding said enzyme
JPWO2019131505A1 (en) * 2017-12-26 2021-01-21 国立大学法人徳島大学 Protein transfer method for filamentous fungal cells and its products
US12103222B2 (en) 2018-12-21 2024-10-01 The Curators Of The University Of Missouri Methods and systems for drawn fused filament fabrication printing

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992007936A1 (en) * 1990-10-24 1992-05-14 The Mount Sinai School Of Medicine Of The City University Of New York Cloning and expression of biologically active alpha-n-acetylgalactosaminidase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992007936A1 (en) * 1990-10-24 1992-05-14 The Mount Sinai School Of Medicine Of The City University Of New York Cloning and expression of biologically active alpha-n-acetylgalactosaminidase

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
WANG A. ET AL.: "Human alpha-N-acetylgalactosaminidase-molecular cloning, nucleotide sequence, and expression of a full-length cDNA", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 265, no. 35, December 1990 (1990-12-01), BALTIMORE, MD US, pages 21859 - 21866, XP002256779 *
YAMAUCHI TOYOAKI ET AL.: "Molecular cloning of two species of cDNAs for human alph-N-acetylgalactosaminidase and expression in mammalian cells", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 170, no. 1, 16 July 1990 (1990-07-16), DULUTH, MINNESOTA US, pages 231 - 237, XP001312681 *

Also Published As

Publication number Publication date
WO1994011518A2 (en) 1994-05-26
CA2149641A1 (en) 1994-05-26
EP0668920A1 (en) 1995-08-30
JPH08503137A (en) 1996-04-09

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