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WO1993018395A1 - Appareil permettant de determiner les proprietes physiques et/ou chimiques d'un echantillon et plus particulierement un echantillon de sang - Google Patents

Appareil permettant de determiner les proprietes physiques et/ou chimiques d'un echantillon et plus particulierement un echantillon de sang Download PDF

Info

Publication number
WO1993018395A1
WO1993018395A1 PCT/GB1993/000475 GB9300475W WO9318395A1 WO 1993018395 A1 WO1993018395 A1 WO 1993018395A1 GB 9300475 W GB9300475 W GB 9300475W WO 9318395 A1 WO9318395 A1 WO 9318395A1
Authority
WO
WIPO (PCT)
Prior art keywords
sample
frequencies
magnitude
frequency
dielectric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB1993/000475
Other languages
English (en)
Inventor
Christopher Barnes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9205175A external-priority patent/GB2260407B/en
Application filed by Individual filed Critical Individual
Priority to AU36429/93A priority Critical patent/AU677001B2/en
Priority to EP93905532A priority patent/EP0630471A1/fr
Publication of WO1993018395A1 publication Critical patent/WO1993018395A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/05—Investigating sedimentation of particle suspensions in blood

Definitions

  • any of the measuring cells methods, and apparatus referred to herein as belonging to this invention may be operated in a differential mode , i:e using two identical sets of said cells , devices or apparatus with the sample being placed in /measured by one member of said set and a dummy sample, containing for example air, water or electroloyte etc; being placed in /measured by second member of said set.
  • a differential mode i:e using two identical sets of said cells , devices or apparatus with the sample being placed in /measured by one member of said set and a dummy sample, containing for example air, water or electroloyte etc; being placed in /measured by second member of said set.
  • FIG 9 the block diagram of the aspect of the invention concerned with fibrinogen or protein assessment when a numeric entry parameter (e:g haemoglobin ) is available or known.
  • a numeric entry parameter e:g haemoglobin
  • Haemoglobin content of blood is known or available from another source such as Coulter or similar cell counter or biochemical optical haemoglobinometer, and is used as the said external entry parameter then the invention configured according to this aspect can be used to provide a simpler and more accurate assessment of fibrinogen level.
  • the main component parts of the system 78-81 operate in exactly the same accord as their equivalent parts indicated in figure 2.
  • the digital voltmeter 84 is used with a differential input and temperature is compensated for using potentiometer 82.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un appareil et un procédé permettant de mettre en corrélation certaines propriétés physiques et chimiques d'un échantillon de sang ou de toute autre substance par la mesure à distance multi-fréquence simultanée du diélectrique, ou lorsqu'une fréquence donnée est appliquée et comparée à un paramètre extérieur proportionnel à l'ampleur d'un paramètre diélectrique sélectionné à une ou plusieurs autres fréquences. L'appareil est utilisé plus particulièrement pour l'évaluation précise instantannée de l'état de sédimentation prévisible de globules rouges ou d'autres paramètres se rapportant aux fibrinogènes ou aux érythrocytes.
PCT/GB1993/000475 1992-03-10 1993-03-08 Appareil permettant de determiner les proprietes physiques et/ou chimiques d'un echantillon et plus particulierement un echantillon de sang Ceased WO1993018395A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU36429/93A AU677001B2 (en) 1992-03-10 1993-03-08 Apparatus for determining the physical and/or chemical properties of a sample, particularly of blood
EP93905532A EP0630471A1 (fr) 1992-03-10 1993-03-08 Appareil permettant de determiner les proprietes physiques et/ou chimiques d'un echantillon et plus particulierement un echantillon de sang

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9205175A GB2260407B (en) 1991-10-10 1992-03-10 Method and devices for A.C measurement on all electromagnetically permeable matter, preferably liquid blood
GB9205175.4 1992-03-10

Publications (1)

Publication Number Publication Date
WO1993018395A1 true WO1993018395A1 (fr) 1993-09-16

Family

ID=10711820

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1993/000475 Ceased WO1993018395A1 (fr) 1992-03-10 1993-03-08 Appareil permettant de determiner les proprietes physiques et/ou chimiques d'un echantillon et plus particulierement un echantillon de sang

Country Status (3)

Country Link
EP (1) EP0630471A1 (fr)
AU (1) AU677001B2 (fr)
WO (1) WO1993018395A1 (fr)

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995014224A1 (fr) * 1993-11-15 1995-05-26 Swelab Instrument Ab Appareil pour determiner la vitesse de sedimentation des eryhtrocytes
US5583432A (en) * 1994-04-11 1996-12-10 Sci-Nostics Limited Electrical method and apparatus for non-contact determination of physical and/or chemical properties of a sample, particularly of blood
WO1998046985A1 (fr) * 1997-04-16 1998-10-22 Kaiku Limited Evaluation de la composition des liquides
GB2336685A (en) * 1998-04-21 1999-10-27 Christopher Barnes Capacitance measuring system
WO2000052453A3 (fr) * 1999-02-28 2001-04-19 Steag Micro Tech Gmbh Procede permettant de determiner les proprietes d'un agent
WO2002073179A1 (fr) * 2001-03-13 2002-09-19 Hall Effect Technologies Ltd. Appareil et procede pour l'analyse de liquides
EP1299029B1 (fr) * 2001-03-06 2006-11-22 Solianis Holding AG Dispositif destines a determiner la concentration de glucose dans un liquide corporel
US7184810B2 (en) 2002-09-04 2007-02-27 Solianis Holding Ag Method and a device for measuring glucose
KR20070034169A (ko) * 2005-09-23 2007-03-28 삼성전자주식회사 테라헤르츠파를 이용한 혈중 성분 농도 측정 장치 및 방법
GB2435097A (en) * 2005-09-30 2007-08-15 Christopher Barnes Assessing erythrocyte membranes using electromagnetic and ultrasound energy.
US7315767B2 (en) 2001-03-06 2008-01-01 Solianis Holding Ag Impedance spectroscopy based systems and methods
US7534208B2 (en) 2002-09-24 2009-05-19 Max Link Device for the measurement of glucose concentrations
RU2393476C2 (ru) * 2008-08-26 2010-06-27 Государственное образовательное учреждение высшего профессионального образования Иркутский государственный университет Устройство для диагностики функционального состояния крови человека
WO2011144511A1 (fr) 2010-05-11 2011-11-24 Fresenius Medical Care Deutschland Gmbh Procédé et dispositif pour déterminer des fractions cellulaires et/ou extracellulaires, en particulier macromoléculaires, de liquides, de préférence de liquides organiques d'êtres vivants
US8197406B2 (en) 2003-12-02 2012-06-12 Biovotion Ag Device and method for measuring a property of living tissue
US8200307B2 (en) 2004-06-07 2012-06-12 Biovotion Ag Method and device for determining a parameter of living tissue
WO2014113333A1 (fr) * 2013-01-15 2014-07-24 The Regents Of The University Of California Dispositif portatif d'imagerie par spectroscopie optique diffuse à large bande pour caractérisation non invasive d'un tissu
US9179856B2 (en) 2009-04-17 2015-11-10 Biovotion Ag Sensing device for body tissue properties
US9568449B2 (en) 2012-01-06 2017-02-14 Bend Research, Inc. Dielectric spectroscopy methods and apparatus
US9713447B2 (en) 2005-11-10 2017-07-25 Biovotion Ag Device for determining the glucose level in body tissue
GB2547271A (en) * 2016-02-11 2017-08-16 Barnes Christopher A contact free blood assessment device and method
EP2375244B1 (fr) * 2009-01-08 2019-10-30 Sony Corporation Analyseur du système de coagulation sanguine, de même que procédé et programme d'analyse de système de coagulation sanguine
US11879860B2 (en) 2019-06-11 2024-01-23 Fresenius Medical Care Holdings, Inc. Systems and methods for measuring electrical characteristic of medical fluids
US12059519B2 (en) 2021-01-11 2024-08-13 Fresenius Medical Care Holdings, Inc. Systems and methods for measuring electrical characteristic of medical fluids

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2400669B (en) * 2003-04-17 2005-12-14 * Barnes Christopher A method and device to obtain haematological parameters and indicators by means of harnessing the dynamics of erythrocyte and other aggregation
GB2414558B (en) * 2003-10-10 2006-04-19 Christopher Barnes Apparatus and method for tracking changes in composition or concentration of a fluid or one or more component parts thereof

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB595720A (en) * 1944-11-06 1947-12-15 Ace Electronics Ltd Electrical apparatus for measuring the proportions of mixtures and solutions
GB1018188A (en) * 1962-11-01 1966-01-26 Kaiser Nils Method for testing the chemical and/or physical condition of media
GB1084860A (en) * 1965-08-24 1967-09-27 Kaiser Nils Improvements in or relating to devices for investigating the chemical and/or physical nature of substance
US3483860A (en) * 1964-11-02 1969-12-16 Norman Stanley Namerow Method for monitoring intrasomatic circulatory functions and organ movement
FR2201762A5 (fr) * 1972-09-29 1974-04-26 Inst Nat Sante Rech Med
FR2378282A1 (fr) * 1977-01-22 1978-08-18 Labora Mannheim Gmbh Dispositif pour determiner la vitesse de sedimentation du sang
US4135131A (en) * 1977-10-14 1979-01-16 The United States Of America As Represented By The Secretary Of The Army Microwave time delay spectroscopic methods and apparatus for remote interrogation of biological targets
US4257001A (en) * 1979-04-13 1981-03-17 John G. Abramo Resonant circuit sensor of multiple properties of objects
GB2130728A (en) * 1982-09-23 1984-06-06 De Beers Ind Diamond Measuring settling rates
EP0157496A2 (fr) * 1984-03-28 1985-10-09 Northern Telecom Limited Procédé pour mesurer la quantité de particules à forte permittivité dans un matériau porteur
DE3637549A1 (de) * 1986-11-04 1988-05-11 Hans Dr Med Rosenberger Messgeraet zur pruefung der dielektrischen eigenschaften biologischer gewebe
DE3722213A1 (de) * 1987-07-04 1989-01-12 Klaus Weber Messverfahren zur bestimmung der konzentration eines mediums
WO1991009295A1 (fr) * 1989-12-13 1991-06-27 Tesi Ab Procede et dispositif de determination du taux de sedimentation du sang
GB2248301A (en) * 1990-09-12 1992-04-01 Ici Plc Apparatus and method for the detection of changes in the composition of a material

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB595720A (en) * 1944-11-06 1947-12-15 Ace Electronics Ltd Electrical apparatus for measuring the proportions of mixtures and solutions
GB1018188A (en) * 1962-11-01 1966-01-26 Kaiser Nils Method for testing the chemical and/or physical condition of media
US3483860A (en) * 1964-11-02 1969-12-16 Norman Stanley Namerow Method for monitoring intrasomatic circulatory functions and organ movement
GB1084860A (en) * 1965-08-24 1967-09-27 Kaiser Nils Improvements in or relating to devices for investigating the chemical and/or physical nature of substance
FR2201762A5 (fr) * 1972-09-29 1974-04-26 Inst Nat Sante Rech Med
FR2378282A1 (fr) * 1977-01-22 1978-08-18 Labora Mannheim Gmbh Dispositif pour determiner la vitesse de sedimentation du sang
US4135131A (en) * 1977-10-14 1979-01-16 The United States Of America As Represented By The Secretary Of The Army Microwave time delay spectroscopic methods and apparatus for remote interrogation of biological targets
US4257001A (en) * 1979-04-13 1981-03-17 John G. Abramo Resonant circuit sensor of multiple properties of objects
GB2130728A (en) * 1982-09-23 1984-06-06 De Beers Ind Diamond Measuring settling rates
EP0157496A2 (fr) * 1984-03-28 1985-10-09 Northern Telecom Limited Procédé pour mesurer la quantité de particules à forte permittivité dans un matériau porteur
DE3637549A1 (de) * 1986-11-04 1988-05-11 Hans Dr Med Rosenberger Messgeraet zur pruefung der dielektrischen eigenschaften biologischer gewebe
DE3722213A1 (de) * 1987-07-04 1989-01-12 Klaus Weber Messverfahren zur bestimmung der konzentration eines mediums
WO1991009295A1 (fr) * 1989-12-13 1991-06-27 Tesi Ab Procede et dispositif de determination du taux de sedimentation du sang
GB2248301A (en) * 1990-09-12 1992-04-01 Ici Plc Apparatus and method for the detection of changes in the composition of a material

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PROCEEDINGS OF THE ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY vol. 10, November 1988, NEW ORLEANS pages 761 - 762 J.M. MCKEE ET AL. 'RADIOFREQUENCY FINGER IMPEDANCE MEASUREMENTS' *

Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995014224A1 (fr) * 1993-11-15 1995-05-26 Swelab Instrument Ab Appareil pour determiner la vitesse de sedimentation des eryhtrocytes
US5583432A (en) * 1994-04-11 1996-12-10 Sci-Nostics Limited Electrical method and apparatus for non-contact determination of physical and/or chemical properties of a sample, particularly of blood
US6511851B1 (en) 1997-04-16 2003-01-28 Kaiku Limited Identifying changes in composition of liquids
WO1998046985A1 (fr) * 1997-04-16 1998-10-22 Kaiku Limited Evaluation de la composition des liquides
GB2336685A (en) * 1998-04-21 1999-10-27 Christopher Barnes Capacitance measuring system
GB2336685B (en) * 1998-04-21 2002-05-15 Christopher Barnes A method and device for the measurement of fixed or time varying capacitance
WO2000052453A3 (fr) * 1999-02-28 2001-04-19 Steag Micro Tech Gmbh Procede permettant de determiner les proprietes d'un agent
EP1299029B1 (fr) * 2001-03-06 2006-11-22 Solianis Holding AG Dispositif destines a determiner la concentration de glucose dans un liquide corporel
US7315767B2 (en) 2001-03-06 2008-01-01 Solianis Holding Ag Impedance spectroscopy based systems and methods
US7693561B2 (en) 2001-03-06 2010-04-06 Solianis Holding Ag Method and device for determining the concentration of a substance in body liquid
WO2002073179A1 (fr) * 2001-03-13 2002-09-19 Hall Effect Technologies Ltd. Appareil et procede pour l'analyse de liquides
US7184810B2 (en) 2002-09-04 2007-02-27 Solianis Holding Ag Method and a device for measuring glucose
US7534208B2 (en) 2002-09-24 2009-05-19 Max Link Device for the measurement of glucose concentrations
US8197406B2 (en) 2003-12-02 2012-06-12 Biovotion Ag Device and method for measuring a property of living tissue
US8200307B2 (en) 2004-06-07 2012-06-12 Biovotion Ag Method and device for determining a parameter of living tissue
KR20070034169A (ko) * 2005-09-23 2007-03-28 삼성전자주식회사 테라헤르츠파를 이용한 혈중 성분 농도 측정 장치 및 방법
GB2435097A (en) * 2005-09-30 2007-08-15 Christopher Barnes Assessing erythrocyte membranes using electromagnetic and ultrasound energy.
GB2435097B (en) * 2005-09-30 2009-08-05 Christopher Barnes Method and apparatus for assessment of the state of a collection of erythrocytemembranes
US9713447B2 (en) 2005-11-10 2017-07-25 Biovotion Ag Device for determining the glucose level in body tissue
RU2393476C2 (ru) * 2008-08-26 2010-06-27 Государственное образовательное учреждение высшего профессионального образования Иркутский государственный университет Устройство для диагностики функционального состояния крови человека
US11067523B2 (en) 2009-01-08 2021-07-20 Sony Corporation Blood coagulation system analysis device, and method and program for analysis of blood coagulation system
EP2375244B1 (fr) * 2009-01-08 2019-10-30 Sony Corporation Analyseur du système de coagulation sanguine, de même que procédé et programme d'analyse de système de coagulation sanguine
EP3620780A1 (fr) * 2009-01-08 2020-03-11 SONY Corporation Dispositif d'analyse de système de coagulation sanguine et procédé et programme d'analyse de système de coagulation sanguine
US9179856B2 (en) 2009-04-17 2015-11-10 Biovotion Ag Sensing device for body tissue properties
WO2011144511A1 (fr) 2010-05-11 2011-11-24 Fresenius Medical Care Deutschland Gmbh Procédé et dispositif pour déterminer des fractions cellulaires et/ou extracellulaires, en particulier macromoléculaires, de liquides, de préférence de liquides organiques d'êtres vivants
US9823207B2 (en) 2010-05-11 2017-11-21 Fresenius Medical Care Deutschland Gmbh Method and device for determining intracellular and/or extracellular, in particular macromolecular fractions of fluids, preferably of body fluids of living organisms
US9568449B2 (en) 2012-01-06 2017-02-14 Bend Research, Inc. Dielectric spectroscopy methods and apparatus
WO2014113333A1 (fr) * 2013-01-15 2014-07-24 The Regents Of The University Of California Dispositif portatif d'imagerie par spectroscopie optique diffuse à large bande pour caractérisation non invasive d'un tissu
GB2547271A (en) * 2016-02-11 2017-08-16 Barnes Christopher A contact free blood assessment device and method
GB2547271B (en) * 2016-02-11 2020-07-22 Barnes Christopher A Contact Free Blood Assessment Device and Method
US11879860B2 (en) 2019-06-11 2024-01-23 Fresenius Medical Care Holdings, Inc. Systems and methods for measuring electrical characteristic of medical fluids
US12276628B2 (en) 2019-06-11 2025-04-15 Fresenius Medical Care Holdings, Inc. Systems and methods for measuring electrical characteristic of medical fluids
US12059519B2 (en) 2021-01-11 2024-08-13 Fresenius Medical Care Holdings, Inc. Systems and methods for measuring electrical characteristic of medical fluids

Also Published As

Publication number Publication date
AU677001B2 (en) 1997-04-10
EP0630471A1 (fr) 1994-12-28
AU3642993A (en) 1993-10-05

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