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WO1993018146A3 - Proteins forming complexes with chaperones and ligands thereof, fragments thereof, preparation thereof and biological uses thereof - Google Patents

Proteins forming complexes with chaperones and ligands thereof, fragments thereof, preparation thereof and biological uses thereof Download PDF

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Publication number
WO1993018146A3
WO1993018146A3 PCT/FR1993/000219 FR9300219W WO9318146A3 WO 1993018146 A3 WO1993018146 A3 WO 1993018146A3 FR 9300219 W FR9300219 W FR 9300219W WO 9318146 A3 WO9318146 A3 WO 9318146A3
Authority
WO
WIPO (PCT)
Prior art keywords
chaperones
ligands
fragments
preparation
forming complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR1993/000219
Other languages
French (fr)
Other versions
WO1993018146A2 (en
Inventor
Marie-Claire Lebeau
Nelly Massol
Michel Renoir
Christine Radanyi
Jean-Paul Mornon
Isabelle Callebaut
Etienne-Emile Baulieu
Beatrice Chambraud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Publication of WO1993018146A2 publication Critical patent/WO1993018146A2/en
Publication of WO1993018146A3 publication Critical patent/WO1993018146A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Nucleotide sequences capable of hybridizing with the nucleotide sequence shown in figure 1, and the corresponding coded amino acid sequences, are disclosed. Said nucleotide sequences are particularly suitable for detecting complementary sequences in biological samples.
PCT/FR1993/000219 1992-03-04 1993-03-04 Proteins forming complexes with chaperones and ligands thereof, fragments thereof, preparation thereof and biological uses thereof Ceased WO1993018146A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR92/02612 1992-03-04
FR9202612A FR2688227A1 (en) 1992-03-04 1992-03-04 PROTEINS FORMING COMPLEXES WITH CHAPERONES AND THEIR LIGANDS, THEIR FRAGMENTS, THEIR PRODUCTION AND THEIR BIOLOGICAL APPLICATIONS.

Publications (2)

Publication Number Publication Date
WO1993018146A2 WO1993018146A2 (en) 1993-09-16
WO1993018146A3 true WO1993018146A3 (en) 1993-11-11

Family

ID=9427364

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1993/000219 Ceased WO1993018146A2 (en) 1992-03-04 1993-03-04 Proteins forming complexes with chaperones and ligands thereof, fragments thereof, preparation thereof and biological uses thereof

Country Status (2)

Country Link
FR (1) FR2688227A1 (en)
WO (1) WO1993018146A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8968720B2 (en) 2008-03-20 2015-03-03 University Of Miami Heat shock protein GP96 vaccination and methods of using same
US9238064B2 (en) 2008-03-03 2016-01-19 University Of Miami Allogeneic cancer cell-based immunotherapy

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750119A (en) * 1994-01-13 1998-05-12 Mount Sinai School Of Medicine Of The City University Of New York Immunotherapeutic stress protein-peptide complexes against cancer
US5997873A (en) * 1994-01-13 1999-12-07 Mount Sinai School Of Medicine Of The City University Of New York Method of preparation of heat shock protein 70-peptide complexes
US5646249A (en) * 1994-02-28 1997-07-08 The United States Of America As Represented By The Department Of Health And Human Services Isolation and characterization of a novel chaperone protein
US5961979A (en) * 1994-03-16 1999-10-05 Mount Sinai School Of Medicine Of The City University Of New York Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens
AU3761695A (en) * 1994-10-14 1996-05-06 Salk Institute For Biological Studies, The Novel immunophilins and corresponding nucleic acids
US5935576A (en) 1995-09-13 1999-08-10 Fordham University Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens
US5985270A (en) * 1995-09-13 1999-11-16 Fordham University Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes
US5837251A (en) 1995-09-13 1998-11-17 Fordham University Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases
DK0928197T3 (en) 1996-09-18 2003-06-23 Zetesis Spa Use of proteins as agents for autoimmune diseases
US5830464A (en) * 1997-02-07 1998-11-03 Fordham University Compositions and methods for the treatment and growth inhibition of cancer using heat shock/stress protein-peptide complexes in combination with adoptive immunotherapy
US6017540A (en) 1997-02-07 2000-01-25 Fordham University Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
IT1290828B1 (en) * 1997-03-25 1998-12-11 Zetesis Spa USE OF EXTRACTABLE PROTEINS FROM ANIMAL ORGANS FOR THE PREPARATION OF MEDICATIONS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS
US5948646A (en) 1997-12-11 1999-09-07 Fordham University Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes
AU757600B2 (en) 1998-02-20 2003-02-27 University Of Miami Modified heat shock protein-antigenic peptide complex
DE19907598A1 (en) * 1999-02-22 2000-08-24 Schulz Burkhard New DNA encoding plant FK506-binding protein analog useful for producing transgenic plants with altered architecture and for studying immunosuppressants
US6335157B1 (en) 1999-05-07 2002-01-01 The European Molecular Biology Laboratory Method based on localization of Hsp90 to the centrosome
CA2410903A1 (en) 2000-06-02 2001-12-06 University Of Connecticut Health Center Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy
CN1635896A (en) 2001-08-20 2005-07-06 康涅狄格大学健康中心 Method for preparing composition comprising heat shock protein or α2-macroglobulin for treating cancer and infectious diseases
MX384422B (en) 2015-02-06 2025-03-14 Heat Biologics Inc Vector that jointly expresses vaccines and co-stimulatory molecules
WO2018071405A1 (en) 2016-10-11 2018-04-19 University Of Miami Vectors and vaccine cells for immunity against zika virus
CA3058938A1 (en) 2017-04-04 2018-10-11 Heat Biologics, Inc. Intratumoral vaccination

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991004321A1 (en) * 1989-09-25 1991-04-04 President And Fellows Of Harvard College Receptor for fk-506
WO1992001052A1 (en) * 1990-07-11 1992-01-23 Tonen Corporation Dna coding for human fk506-binding protein and expression thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991004321A1 (en) * 1989-09-25 1991-04-04 President And Fellows Of Harvard College Receptor for fk-506
WO1992001052A1 (en) * 1990-07-11 1992-01-23 Tonen Corporation Dna coding for human fk506-binding protein and expression thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIOCHEMISTRY. vol. 29, no. 21, 1990, EASTON, PA US pages 5145 - 5152 SANCHEZ R. ET AL. 'The 56-59-kilodalton protein identified in untransformed receptor complexes is...' cité dans la demande *
GENBANK DATABASE,BETHESDA US Acc.No.x17069,Nelki S. al.:'Identification and DNA sequence of a family of related cDNA's one of which is haploid specific and...' *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9238064B2 (en) 2008-03-03 2016-01-19 University Of Miami Allogeneic cancer cell-based immunotherapy
US8968720B2 (en) 2008-03-20 2015-03-03 University Of Miami Heat shock protein GP96 vaccination and methods of using same

Also Published As

Publication number Publication date
FR2688227A1 (en) 1993-09-10
WO1993018146A2 (en) 1993-09-16

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