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WO1993016180A2 - Sequences genetiques pour un antigene 90k associe aux tumeurs (ir-95) - Google Patents

Sequences genetiques pour un antigene 90k associe aux tumeurs (ir-95) Download PDF

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Publication number
WO1993016180A2
WO1993016180A2 PCT/EP1993/000382 EP9300382W WO9316180A2 WO 1993016180 A2 WO1993016180 A2 WO 1993016180A2 EP 9300382 W EP9300382 W EP 9300382W WO 9316180 A2 WO9316180 A2 WO 9316180A2
Authority
WO
WIPO (PCT)
Prior art keywords
sep
antigen
leu
ala
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1993/000382
Other languages
English (en)
Other versions
WO1993016180A3 (fr
WO1993016180A1 (fr
Inventor
Axel Ullrich
Irmingard Sures
Mohammad Azam
Stefano Iacobelli
Clara Natoli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften
Publication of WO1993016180A1 publication Critical patent/WO1993016180A1/fr
Publication of WO1993016180A2 publication Critical patent/WO1993016180A2/fr
Publication of WO1993016180A3 publication Critical patent/WO1993016180A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Antigène 90K associé aux tumeurs et sensiblement purifié, ou un ou plusieurs fragments de celui-ci. Il est obtenu notamment à partir du liquide de culture de la lignée cellulaire CG-5 du cancer du sein chez la femme; du sérum d'une personne atteinte du cancer ovarien. L'antigène natif a un poids moléculaire de 95 000 daltons environ et il est présent sous la forme d'un complexe à poids moléculaire élevé. On a prévu la purification et la caractérisation de l'antigène, ainsi que ses utilisations. On a également prévu des séquences nucléotidiques codant l'antigène 90K, ou un ou plusieurs fragments de celui-ci, des véhicules contenant la séquence génétique, des hôtes transformés à l'adie de ceux-ci, ainsi que la production de l'antigène, ou de ses fragments, à l'aide de l'hôte transformé.
PCT/EP1993/000382 1992-02-17 1993-02-17 Sequences genetiques pour un antigene 90k associe aux tumeurs (ir-95) Ceased WO1993016180A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM92A000100 1992-02-17
ITRM920100A IT1254309B (it) 1992-02-17 1992-02-17 Sequenze genetiche per l'antigene 90k associato a tumori.

Publications (3)

Publication Number Publication Date
WO1993016180A1 WO1993016180A1 (fr) 1993-08-19
WO1993016180A2 true WO1993016180A2 (fr) 1993-08-19
WO1993016180A3 WO1993016180A3 (fr) 1993-09-30

Family

ID=11400692

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1993/000382 Ceased WO1993016180A2 (fr) 1992-02-17 1993-02-17 Sequences genetiques pour un antigene 90k associe aux tumeurs (ir-95)

Country Status (5)

Country Link
CN (1) CN1076489A (fr)
AU (1) AU3497893A (fr)
IT (1) IT1254309B (fr)
WO (1) WO1993016180A2 (fr)
ZA (1) ZA931101B (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995012681A1 (fr) * 1993-11-05 1995-05-11 New York University Procede relatif a l'ir-95
WO2001051515A3 (fr) * 2000-01-10 2002-01-24 Chiron Corp Genes exprimes de maniere differentielle dans le cancer du sein
WO2001057207A3 (fr) * 2000-02-04 2002-07-04 Corixa Corp Compositions et methodes destinees a la therapie et au diagnostic du cancer de l'ovaire
US7081517B2 (en) 2000-01-10 2006-07-25 Chiron Corporation Genes differentially expressed in breast cancer
WO2010097825A1 (fr) * 2009-02-25 2010-09-02 Stefano Iacobelli Utilisation d'anticorps monoclonaux anti-90k pour la prévention et le traitement de tumeurs et des métastases de celles-ci
WO2020099235A1 (fr) 2018-11-12 2020-05-22 Mediapharma S.R.L. Anticorps bispécifiques dirigés contre 90k humain, et soit l'endosialine, soit her3

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101962405A (zh) * 2010-09-30 2011-02-02 南开大学 一种人源乳腺癌抗原及其抗体
CN110455848B (zh) * 2018-05-08 2024-02-23 国家纳米科学中心 基于络合反应放大信号的铁离子纵向弛豫时间传感器及其构建方法、用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL76877A (en) * 1984-11-02 1991-11-21 Oncogen Diagnostic method for the determination of human non-small cell lung carcinomas employing novel monoclonal antibodies and compositions containing said antibodies
IT1239719B (it) * 1990-04-23 1993-11-15 Univ Degli Studi Annunzio Uso dell'anticorpo monoclonale sp-2 nella diagnostica clinica ed il monitoraggio del progredire dell'infezione hiv

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995012681A1 (fr) * 1993-11-05 1995-05-11 New York University Procede relatif a l'ir-95
WO2001051515A3 (fr) * 2000-01-10 2002-01-24 Chiron Corp Genes exprimes de maniere differentielle dans le cancer du sein
US7081517B2 (en) 2000-01-10 2006-07-25 Chiron Corporation Genes differentially expressed in breast cancer
EP1985701A3 (fr) * 2000-01-10 2009-01-07 Novartis Vaccines and Diagnostics, Inc. Gène s'exprimant par action différentielle dans le cancer du sein
US7605246B2 (en) 2000-01-10 2009-10-20 Novartis Vaccines And Diagnostics, Inc. Genes differentially expressed in breast cancer
US8236928B2 (en) 2000-01-10 2012-08-07 Novartis Vaccines And Diagnostics, Inc. Genes differentially expressed in breast cancer
WO2001057207A3 (fr) * 2000-02-04 2002-07-04 Corixa Corp Compositions et methodes destinees a la therapie et au diagnostic du cancer de l'ovaire
WO2010097825A1 (fr) * 2009-02-25 2010-09-02 Stefano Iacobelli Utilisation d'anticorps monoclonaux anti-90k pour la prévention et le traitement de tumeurs et des métastases de celles-ci
US8679495B2 (en) 2009-02-25 2014-03-25 Mediapharma S.R.L. Use of anti-90K monoclonal antibodies for the prevention and treatment of tumors and metastases thereof
WO2020099235A1 (fr) 2018-11-12 2020-05-22 Mediapharma S.R.L. Anticorps bispécifiques dirigés contre 90k humain, et soit l'endosialine, soit her3

Also Published As

Publication number Publication date
ITRM920100A0 (it) 1992-02-17
ZA931101B (en) 1994-08-17
ITRM920100A1 (it) 1993-08-17
WO1993016180A3 (fr) 1993-09-30
AU3497893A (en) 1993-09-03
IT1254309B (it) 1995-09-14
CN1076489A (zh) 1993-09-22

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