[go: up one dir, main page]

WO1993016178A3 - Sequences characteristic of human gene transcription product - Google Patents

Sequences characteristic of human gene transcription product Download PDF

Info

Publication number
WO1993016178A3
WO1993016178A3 PCT/US1993/001294 US9301294W WO9316178A3 WO 1993016178 A3 WO1993016178 A3 WO 1993016178A3 US 9301294 W US9301294 W US 9301294W WO 9316178 A3 WO9316178 A3 WO 9316178A3
Authority
WO
WIPO (PCT)
Prior art keywords
human gene
gene transcription
transcription product
sequences characteristic
sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1993/001294
Other languages
French (fr)
Other versions
WO1993016178A2 (en
Inventor
Craig J Venter
Mark D Adams
Ruben F Moreno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Department of the Army
Original Assignee
United States Department of the Army
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United States Department of the Army filed Critical United States Department of the Army
Publication of WO1993016178A2 publication Critical patent/WO1993016178A2/en
Publication of WO1993016178A3 publication Critical patent/WO1993016178A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Partial and complete human cDNA and genomic sequences corresponding to particular expressed sequence tags (ESTs). The ESTs are cDNA sequences that are generally between 150 and 500 base pairs in length, are derived from human brain cDNA libraries, correspond to genes transcribed in human brain, and have base sequences identified herein as SEQ ID NOS: 1-2421.
PCT/US1993/001294 1992-02-12 1993-02-12 Sequences characteristic of human gene transcription product Ceased WO1993016178A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83719592A 1992-02-12 1992-02-12
US07/837,195 1992-02-12

Publications (2)

Publication Number Publication Date
WO1993016178A2 WO1993016178A2 (en) 1993-08-19
WO1993016178A3 true WO1993016178A3 (en) 1993-11-25

Family

ID=25273788

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/001294 Ceased WO1993016178A2 (en) 1992-02-12 1993-02-12 Sequences characteristic of human gene transcription product

Country Status (2)

Country Link
AU (1) AU3665893A (en)
WO (1) WO1993016178A2 (en)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995014772A1 (en) * 1993-11-12 1995-06-01 Kenichi Matsubara Gene signature
EP0733110A1 (en) 1993-12-24 1996-09-25 University of Wales College of Medicine Tuberous sclerosis 2 gene and uses thereof
US5605797A (en) * 1994-09-15 1997-02-25 Board Of Trustees Operating Michigan State University Bovine β-mannosidase gene and methods of use
US5863744A (en) * 1994-10-03 1999-01-26 New England Deaconess Hospital Corporation Neural cell protein marker RR/B and DNA encoding same
US5985598A (en) 1994-10-27 1999-11-16 Thomas Jefferson University TCL-1 gene and protein and related methods and compositions
US7175995B1 (en) 1994-10-27 2007-02-13 Thomas Jefferson University TCL-1 protein and related methods
US5985554A (en) * 1994-11-02 1999-11-16 Takeda Chemical Industries, Ltd. Method of probing the function of proteins or peptides encoded by partially sequenced cDNAs by inhibiting protein synthesis with antisense oligonucleotides
CA2225824A1 (en) * 1995-06-30 1997-01-23 Human Genome Sciences, Inc. Breast specific genes and proteins
US5695937A (en) * 1995-09-12 1997-12-09 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression
US5866330A (en) 1995-09-12 1999-02-02 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression
AU4105396A (en) 1995-11-02 1997-05-29 Human Genome Sciences, Inc. Mammary transforming protein
US6541224B2 (en) 1996-03-14 2003-04-01 Human Genome Sciences, Inc. Tumor necrosis factor delta polypeptides
US7217788B2 (en) 1996-03-14 2007-05-15 Human Genome Sciences, Inc. Human tumor necrosis factor delta polypeptides
US6509170B1 (en) 1996-03-14 2003-01-21 Human Genome Sciences, Inc. Polynucleotides encoding human tumor necrosis factor delta
US6468766B1 (en) * 1996-03-15 2002-10-22 President And Fellows Of Harvard College Aortic carboxypeptidase-like polypeptide
WO1997042218A1 (en) * 1996-05-06 1997-11-13 Chiron Corporation MAMMALIAN SEX COMB ON MIDLEG (MAMMALIAN Scm) ACTS AS AN ONCOGENE
WO1997042213A1 (en) * 1996-05-08 1997-11-13 Chiron Corporation MAMMALIAN ADDITIONAL SEX COMBS (MAMMALIAN Asx) ACTS AS AN ONCOGENE
JP4382879B2 (en) 1996-07-12 2009-12-16 ジェネンテック・インコーポレーテッド Gamma-Heregulin
US5874285A (en) * 1996-09-13 1999-02-23 Incyte Pharmaceuticals, Inc. Polynucleotide encoding a novel human nm23-like protein
US5917028A (en) * 1996-10-29 1999-06-29 Incyte Pharmaceuticals, Inc. Human phosphoprotein
US5840559A (en) * 1996-10-30 1998-11-24 Incyte Pharmaceuticals, Inc. Human spermidine/spermine N1-acetyltransferase
US5889170A (en) * 1997-01-31 1999-03-30 Incyte Pharmaceuticals, Inc. Human integral membrane protein
US5939271A (en) 1997-02-19 1999-08-17 The Regents Of The University Of California Netrin receptor
US5955312A (en) * 1997-02-24 1999-09-21 Incyte Pharmaceuticals, Inc. DNA encoding a novel microtubule-associated protein
AU6439598A (en) * 1997-02-26 1998-09-18 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
US6171787B1 (en) * 1997-06-26 2001-01-09 Abbott Laboratories Member of the TNF family useful for treatment and diagnosis of disease
US5948619A (en) * 1997-07-31 1999-09-07 Incyte Pharmaceuticals, Inc. Human zygin-1
EP1016718A1 (en) * 1997-08-13 2000-07-05 Chugai Research Institute for Molecular Medicine Inc. PROTEIN HAVING Zn FINGER-LIKE MOTIF
US6130068A (en) * 1998-10-26 2000-10-10 Immunex Corporation Viral encoded semaphorin protein receptor DNA and polypeptides
US6562949B1 (en) 1997-10-28 2003-05-13 Immunex Corporation Antibodies to viral encoded semaphorin protein receptor polypeptides
CA2307014A1 (en) * 1997-10-28 1999-05-06 Immunex Corporation Viral encoded semaphorin protein receptor dna and polypeptides
US7214497B2 (en) 1997-10-28 2007-05-08 Immunex Corporation Viral encoded semaphorin protein receptor DNA and polypeptides
US6277565B1 (en) * 1997-11-06 2001-08-21 Millennium Pharmaceuticals, Inc. OCT-3 gene encoding transporter-like molecules
US5916753A (en) * 1997-11-13 1999-06-29 Incyte Pharmaceuticals, Inc. SH3-containing proteins
WO2000006708A1 (en) * 1998-07-29 2000-02-10 Kyowa Hakko Kogyo Co., Ltd. Novel polypeptide
US6472517B1 (en) * 1998-10-09 2002-10-29 Genset S.A. Nucleic acids encoding human CIDE-B protein and polymorphic markers thereof
US6355788B1 (en) 1998-10-15 2002-03-12 Zymogenetics, Inc. Follistatin-related protein zfsta2
CA2347968A1 (en) * 1998-10-15 2000-04-20 Zymogenetics, Inc. Follistatin-related protein zfsta2
EP1141288A2 (en) * 1998-12-18 2001-10-10 Incyte Pharmaceuticals, Inc. Lymphocytic membrane proteins
IL178921A0 (en) 1998-12-24 2007-03-08 Yeda Res & Dev Caspase-8 interacting proteins
GB9900167D0 (en) * 1999-01-06 1999-02-24 Univ Leeds Wound an tissue healing and orofacial clefting
DE19908423A1 (en) * 1999-02-26 2000-08-31 Deutsches Krebsforsch Protein involved in the development of the CNS
JP2002537832A (en) * 1999-03-09 2002-11-12 シエーリング アクチエンゲゼルシャフト Human nucleic acid and protein sequences from endothelial cells
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
CA2384777A1 (en) 1999-09-10 2001-03-15 Charles S. Zuker T2r taste receptor family
EP1222206A1 (en) * 1999-10-22 2002-07-17 Wyeth Pablo, a polypeptide that interacts with bcl-xl, and uses related thereto
US7164001B2 (en) * 2000-01-20 2007-01-16 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
WO2001055300A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2001081361A1 (en) * 2000-04-11 2001-11-01 Cogent Neuroscience, Inc. Compositions and method for diagnosing and treating conditions, disorders, or diseases involving cell death
EP1209229A1 (en) * 2000-11-21 2002-05-29 Klaus-Peter Department of Psychiatry and Psychotherapy University of Würzburg Lesch Gene involved in schizophrenia
US20060063152A1 (en) * 2000-12-22 2006-03-23 Osamu Ohara Novel gene and protein encoded by the gene
US7927597B2 (en) 2001-04-10 2011-04-19 Agensys, Inc. Methods to inhibit cell growth
EP1573024A4 (en) 2001-04-10 2007-08-29 Agensys Inc Nuleic acids and corresponding proteins useful in the detection and treatment of various cancers
AU2002311976A1 (en) 2001-05-24 2002-12-03 Human Genome Sciences, Inc. Antibodies against tumor necrosis factor delta (april)
WO2004016733A2 (en) 2002-08-16 2004-02-26 Agensys, Inc. Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
CA2798390A1 (en) 2010-05-06 2011-11-10 Novartis Ag Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (lrp6) multivalent antibodies
CN103038258B (en) 2010-05-06 2017-02-15 诺华股份有限公司 Compositions and methods of use of antibodies for treating low-density lipoprotein-related protein 6 (LRP6)
CA2854457A1 (en) 2011-11-04 2013-05-10 David Jenkins Low density lipoprotein-related protein 6 (lrp6) - half life extender constructs

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NATURE vol. 355, 13 February 1992, LONDON, UNITED KINGDOM pages 632 - 634 M.D. ADAMS 'Sequence Identification of 2375 human brain genes' *
SCIENCE vol. 252, 21 June 1991, WASHINGTON, DC, USA pages 1651 - 1656 M.D. ADAMS ET AL. 'Complementary DNA Sequencing: Expressed Sequence Tags and Human genome Projects' *

Also Published As

Publication number Publication date
AU3665893A (en) 1993-09-03
WO1993016178A2 (en) 1993-08-19

Similar Documents

Publication Publication Date Title
WO1993016178A3 (en) Sequences characteristic of human gene transcription product
AU5914196A (en) Hydrophobins from edible fungi, genes, nucleotide sequences and dna-fragments encoding for said hydrophobins, and expression thereof
WO1999006552A3 (en) 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN BRAIN
CA2200371A1 (en) Human npik gene
WO1994001548A3 (en) Human nucleic acid fragments, isolated from brain adrenal tissue, placenta or bone narrow
RU93058460A (en) POLYNUCLEOTIDE, METHODS OF GETTING PLANTS, PLANT GENE, CELLS, FRUITS, SEEDS, METHODS OF GETTING SEEDS, APPLICATION OF OLIGONUCLEOTIDE, PLASMIDE, MICROORGANISM
WO1999053051A3 (en) 5' ests and encoded human proteins
EP1754789A3 (en) Bacillus strains and pesticidal proteins
WO1999006554A3 (en) 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN MUSCLE AND OTHER MESODERMAL TISSUES
CY1106216T1 (en) 5´ ESTs FOR NON-TISSUE-SPECIFIC SECRETORY PROTEINS
AU2240492A (en) Sequences characteristic of human gene transcription product
CA2153254A1 (en) Cloning of enterokinase and method of use
WO1999006549A3 (en) 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN TESTIS AND OTHER TISSUES
EP0834566A3 (en) Cotton plant gene
AU4331497A (en) Oligomers which inhibit expression of interleukin genes
WO1994008052A1 (en) Methods for sequencing synthetic oligonucleotides containing non-phosphodiester internucleotide linkages
WO1999006551A3 (en) 5' ESTs FOR SECRETED PROTEINS IDENTIFIED FROM BRAIN TISSUES
CY1105398T1 (en) 5΄ ESTs FOR SECRETORY PROTEINS EXPRESSED IN DIFFERENT TISSUES
AU2967497A (en) Enhancement of gene expression
PL331542A1 (en) Immunity against nematodes and/or plant louses
AU6724794A (en) GRB3-3 gene, its variants and their uses
AU1789292A (en) Yeast promoter and use thereof
WO1999046374A3 (en) Human nucleic acid sequences from prostate tumour tissue
WO1999054447A3 (en) Human nucleic acid sequences of bladder tumour tissue
WO1997006259A3 (en) Resistance against wilt inducing fungi

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU CA JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

AK Designated states

Kind code of ref document: A3

Designated state(s): AU CA JP

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
NENP Non-entry into the national phase

Ref country code: CA

122 Ep: pct application non-entry in european phase