WO1992009238A1 - Procede et appareil de traitement des tissus adipeux chez l'homme - Google Patents
Procede et appareil de traitement des tissus adipeux chez l'homme Download PDFInfo
- Publication number
- WO1992009238A1 WO1992009238A1 PCT/EP1990/002335 EP9002335W WO9209238A1 WO 1992009238 A1 WO1992009238 A1 WO 1992009238A1 EP 9002335 W EP9002335 W EP 9002335W WO 9209238 A1 WO9209238 A1 WO 9209238A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- probe
- ultrasonic energy
- fat
- tissue
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00234—Surgical instruments, devices or methods for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00261—Discectomy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/08—Lipoids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
- A61N2007/0008—Destruction of fat cells
Definitions
- This invention relates to a method and apparatus for destroying human fat cells and tissue safely and expeditiously directly inside the body or externally through the skin for ultimate removal or other liposculpturing treatment.
- the present invention provides a novel technique for destroying fat cells and fat tissue areas directly inside the body or externally through the skin, significantly reducing surgical trauma by use of ultrasonic energy.
- an ultrasonic probe disposed externally of the body, cavitation can be induced in adjacent fat cells beneath the skin destroying fat tissue without any incision.
- a small incision may be made and a liposuction device used for sucking out the destroyed fat tissues.
- direct fat cell contact with a long titanium ultrasonic probe through a small incision may be employed to destroy the fat cells. Fat cells and tissue adjacent the probe end can be destroyed.
- the use of the present method and apparatus greatly reduces the surgical trauma and risks presently experienced in liposuction and liposculpturing techniques while reducing the time of the procedures.
- a method and apparatus for destruction of human fat cells and tissue using ultrasonic energy application either directly within the body or externally through the patients skin broadly encompasses selecting the area of treatment, positioning an ultrasonic probe at the desired treatment location and applying ultrasonic energy to the human fat cells and tissues to be destroyed.
- the removal of the destroyed fat cells may be done through a small incision
- SUBSTITUTE SHEET with a liposuction device which sucks out the residual oils and residual fat tissue from the area subjected to ultrasonic energy between 20,000 Hz and 3,000,000 Hz.
- a plate-shaped ultrasonic probe of a predetermined size having a smooth, polished surface and centre connector coupled to the ultrasonic generator is utilized.
- a gel is applied to the outer skin of the patient in the probe contact area. Fat cells below the skin receiving the ultrasonic energy burst due to the application of ultrasonic energy causing their destruction.
- the probe may be applied with a slow circular motion around the body area to be treated.
- a small incision may be made in the patient's skin and a liposuction device inserted there through which sucks out the destroyed fat cells, tissue and oils and any residual cell material.
- the fat cells may be destroyed internally.
- a long, narrow ultrasonic probe (preferably made of titanium) is connected to an ultrasonic generator. The narrow probe is inserted through a small incision in the patient's skin in the treatment area and the ultrasonic energy applied, thus destroying and bursting fat cells and tissue immediately surrounding the blunt end of the probe.
- liposuction with a suction device is performed through the incision to remove the oil, dead cells and tissue although this is unnecessary as the destroyed material will be reabsorbed by the body.
- the patient may be treated either externally with the external surgical probe or internally through a small incision using the elongated blunt tip probe, both probes providing ultrasonic energy directed to the fat cells to be treated.
- the total time period of ultrasonic energy application will be normally less than one minute for the internal
- the technique and instruments provided are not only useful for abdominal areas of patients but can also be directed to other specific areas such as knees or saddle bags and buttocks in which autogolous collagen may be used for remodelling and in which the destroyed fat tissue materials may be allowed to reabsorb into the body and not be removed by suction after the ultrasonic exposure of the areas.
- Yet still another object of this invention is to provide a method and apparatus for performing liposculpturing and lipotripsion for treating human fat cells and tissue which includes internal or external ultrasonic application respectively.
- Figure 1 shows a perspective view of an apparatus used in the present invention which includes either an external probe or internal probe connected to the ultrasonic generator.
- Figure 2 shows a side elevational view of the external probe used with the present invention.
- Figure 3 shows a front elevational view with the probe used with the external application of the present invention.
- Figure 4 shows a perspective view of the external probe used with the present invention.
- S U BS TITUTESHEET Figure 5 shows a perspective view of an internal probe for internal application of ultrasonic energy in accordance with the present invention.
- the method in accordance with the invention is accomplished by locating the fat cell and tissue area to be treated and applying ultrasonic energy to a limited, defined area of human fat cells and tissue, with either a flat ultrasonic probe externally through the skin or with a narrow internal probe typically for the ultimate removal of the destroyed fat cells and tissue or for liposculpturing.
- the method involves the application of ultrasonic energy in the range of 20,000 Hz to 3,000,000 Hz with the use of specially designed probes for internal or external use.
- the fat cells are destroyed by the bursting of the cells releasing oil and residual tissue, all of which can be removed by suction quickly and efficiently, or can be left in the body for a progressive reabsorption.
- a device as shown in Figure 1 may be used comprising an ultrasonic generating system 18 connected to a standard AC power supply that includes a foot switch 22 connected by wires 20 into the generator 18 for controlling the application of the energy. Also attached to the power supply and generator 18 is a convertor 16 that is used to attach either a probe 10 which is used for external application of ultrasonic energy through the skin of the patient or probe 12 which with a small incision can be inserted into a patient for internal ultrasonic application.
- a device as the VIBRACELL VC 50 is manufactured by Sonics and Materials, Inc., of Danbury, Connecticut.
- the external probe is shown comprised of a metal circular disk of an ultrasonic transmitting material (preferably titanium) which is perfectly smooth and polished on outside face 10a and which includes a connector 10c that connects to the converter of the ultrasonic generator and a central flange lOd that transmits the energy into the disk from the converter connection.
- the probe diameter may be a desired, preferably
- the connector 10c includes a threaded connector to converter 16 shown in Figure 1 for the application of ultrasonic energy from 20,000 to 3,000,000 Hz.
- the probe 10 in conjunction with a gel applied on the skin of the patient can then be slowly moved in a circular motion on the skin around the area of fat cells below the skin which are to be destroyed by the ultrasonic energy. It is believed that cavitation in the fat cells is produced through the skin of the patient and the fat cells burst under the action of the ultrasonic energy. After the ultrasonic energy application is completed, destroying a reasonable number of fat tissue and fat cells desired beneath the skin, the residual is progressively reabsorbed by the body.
- the device is especially useful for treating small areas such as knees or saddle bags.
- an elongated titanium probe 12 is utilised which includes a thin cylindrical shaft portion 12a terminating in a blunt tip 12b from which the ultrasonic energy is transmitted.
- a threaded connector 12c connects the probe to the convertor 16 of Figure 1 of the ultrasonic energy generator.
- the probe 12 shown in Figure and shaft portion 12a is circular in cross section and includes an enlarged cylindrical portion 12d which connects the shaft 12a to the connector 12c.
- the length of the shaft may be between 10 and 30 centimetres and the diameter between 2 and 6 millimetres.
- the probe 12 is inserted through the small incision under the skin into the area of the fat cells to be destroyed. Ultrasonic energy is then applied through the actuation of foot switch 22 shown in Figure 1 so that ultrasonic energy emerges from the blunt tip end and is concentrated in the area for the fat tissue destruction. After the ultrasonic treatment, a small liposuction device may be inserted in the treated area to remove the fat cell oil and dead cells or in some situations
- fat cells and tissue may be precisely and safely destroyed to permit removal or regeneration and liposculpturing in desired areas of the human body eliminating traumatic and dangerous cutting surgical techniques previously used.
- the invention also provides equipment for performing both external and internal ultrasonic destruction of fat cells and tissue in predetermined areas quickly and safely.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Abstract
Procédé et appareil servant à détruire en sécurité et de manière rapide et pratique les tissus adipeux chez l'homme, par l'application interne ou externe d'énergie ultrasonique à l'aide de sondes spéciales. Lors d'une application externe de l'énergie ultrasonique, on place une sonde appropriée (10) contre la peau à proximité des cellules et tissus adipeux à détruire. La sonde produit de l'énergie ultrasonique qui détruit les cellules et tissus adipeux se trouvant sous la sonde. Une fois que les cellules et tissus adipeux sont déchirés et détruits par l'énergie ultrasonique, on retire la sonde. On peut éventuellement introduire par voie chirurgicale dans la zone de destruction un dispositif d'aspiration, destiné à évacuer les cellules et tissus détruits. Par contre, lors d'une application interne de l'énergie ultrasonique, on introduit une sonde appropriée (12) dans le corps du sujet à travers une petite incision. La sonde produit de l'énergie ultrasonique qui détruit les cellules et tissus adipeux entourant la sonde. Une fois que les cellules et tissus adipeux sont déchirés et détruits par l'énergie ultrasonique, on retire la sonde du corps du sujet. On peut éventuellement introduire par voie chirurgicale dans la zone de destruction un dispositif d'aspiration destiné à évacuer les cellules et tissus détruits.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19910905605 EP0513244A1 (fr) | 1990-11-30 | 1990-11-30 | Procede et appareil de traitement des tissus adipeux chez l'homme |
| PCT/EP1990/002335 WO1992009238A1 (fr) | 1990-11-30 | 1990-11-30 | Procede et appareil de traitement des tissus adipeux chez l'homme |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP1990/002335 WO1992009238A1 (fr) | 1990-11-30 | 1990-11-30 | Procede et appareil de traitement des tissus adipeux chez l'homme |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1992009238A1 true WO1992009238A1 (fr) | 1992-06-11 |
Family
ID=8165552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP1990/002335 Ceased WO1992009238A1 (fr) | 1990-11-30 | 1990-11-30 | Procede et appareil de traitement des tissus adipeux chez l'homme |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP0513244A1 (fr) |
| WO (1) | WO1992009238A1 (fr) |
Cited By (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0716579A4 (fr) * | 1993-08-03 | 1998-03-25 | Misonix Inc | Appareil de liposuccion et procede associe |
| WO1998057707A1 (fr) * | 1997-06-17 | 1998-12-23 | Ferton Holding | Instrument medical pour le traitement de tissus biologiques |
| US6013048A (en) * | 1997-11-07 | 2000-01-11 | Mentor Corporation | Ultrasonic assisted liposuction system |
| FR2782645A1 (fr) * | 1998-08-28 | 2000-03-03 | Juliette Dubois | Dispositif de liposuccion des graisses associe a un traitement de la peau par aspiration sous vide |
| EP0975273A4 (fr) * | 1997-04-17 | 2000-05-31 | Barry Silberg | Technique preoperatoire |
| EP1502626A1 (fr) * | 1997-06-17 | 2005-02-02 | Ferton Holding SA | Appareil médical pour le traitement des tissues biologiques |
| US7588547B2 (en) | 2005-09-07 | 2009-09-15 | Cabochon Aesthetics, Inc. | Methods and system for treating subcutaneous tissues |
| WO2009095894A3 (fr) * | 2008-02-01 | 2009-12-30 | Alma Lasers Ltd. | Appareil et procédé pour dégradation sélective d’adipocytes par ultrason |
| WO2011073358A1 (fr) * | 2009-12-16 | 2011-06-23 | Switech Medical Ag | Dispositif destiné à générer un champ ultrasonore et procédé de lypolyse |
| US20120157888A1 (en) * | 2010-12-17 | 2012-06-21 | Nino Grob | Device for generating an ultrasonic field and method of lypolysis |
| US8894678B2 (en) | 2009-08-07 | 2014-11-25 | Ulthera, Inc. | Cellulite treatment methods |
| US9011473B2 (en) | 2005-09-07 | 2015-04-21 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| US9039722B2 (en) | 2007-10-09 | 2015-05-26 | Ulthera, Inc. | Dissection handpiece with aspiration means for reducing the appearance of cellulite |
| US9248317B2 (en) | 2005-12-02 | 2016-02-02 | Ulthera, Inc. | Devices and methods for selectively lysing cells |
| US9272124B2 (en) | 2005-12-02 | 2016-03-01 | Ulthera, Inc. | Systems and devices for selective cell lysis and methods of using same |
| US9358033B2 (en) | 2005-09-07 | 2016-06-07 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
| US9358064B2 (en) | 2009-08-07 | 2016-06-07 | Ulthera, Inc. | Handpiece and methods for performing subcutaneous surgery |
| US9486274B2 (en) | 2005-09-07 | 2016-11-08 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| WO2017149506A1 (fr) * | 2016-03-03 | 2017-09-08 | Alma Lasers Ltd. | Sonotrode |
| EP3461438A1 (fr) * | 2009-07-08 | 2019-04-03 | Sanuwave, Inc. | Système de traitement par ondes de chocs intracorporelles et extracorporelles combinées |
| US10548659B2 (en) | 2006-01-17 | 2020-02-04 | Ulthera, Inc. | High pressure pre-burst for improved fluid delivery |
| US11096708B2 (en) | 2009-08-07 | 2021-08-24 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4823042A (en) * | 1986-07-18 | 1989-04-18 | Rich-Mar Corporation | Sonic transducer and method for making the same |
| WO1989007468A1 (fr) * | 1988-02-09 | 1989-08-24 | Fellner Donald G | Procede d'elimination de tissu adipeux du corps |
| EP0331313A1 (fr) * | 1988-02-29 | 1989-09-06 | Tulio Parisi | Sonde à ultrasons pour liposucction |
-
1990
- 1990-11-30 WO PCT/EP1990/002335 patent/WO1992009238A1/fr not_active Ceased
- 1990-11-30 EP EP19910905605 patent/EP0513244A1/fr not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4823042A (en) * | 1986-07-18 | 1989-04-18 | Rich-Mar Corporation | Sonic transducer and method for making the same |
| WO1989007468A1 (fr) * | 1988-02-09 | 1989-08-24 | Fellner Donald G | Procede d'elimination de tissu adipeux du corps |
| EP0331313A1 (fr) * | 1988-02-29 | 1989-09-06 | Tulio Parisi | Sonde à ultrasons pour liposucction |
Cited By (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0716579A4 (fr) * | 1993-08-03 | 1998-03-25 | Misonix Inc | Appareil de liposuccion et procede associe |
| EP0975273A4 (fr) * | 1997-04-17 | 2000-05-31 | Barry Silberg | Technique preoperatoire |
| WO1998057707A1 (fr) * | 1997-06-17 | 1998-12-23 | Ferton Holding | Instrument medical pour le traitement de tissus biologiques |
| EP1502626A1 (fr) * | 1997-06-17 | 2005-02-02 | Ferton Holding SA | Appareil médical pour le traitement des tissues biologiques |
| US6013048A (en) * | 1997-11-07 | 2000-01-11 | Mentor Corporation | Ultrasonic assisted liposuction system |
| FR2782645A1 (fr) * | 1998-08-28 | 2000-03-03 | Juliette Dubois | Dispositif de liposuccion des graisses associe a un traitement de la peau par aspiration sous vide |
| WO2000012149A1 (fr) | 1998-08-28 | 2000-03-09 | Juliette Dubois | Dispositif de liposuccion des graisses associe a un traitement de la peau par aspiration sous vide |
| US8366643B2 (en) | 2005-09-07 | 2013-02-05 | Cabochon Aesthetics, Inc. | System and method for treating subcutaneous tissues |
| US9364246B2 (en) | 2005-09-07 | 2016-06-14 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| US9011473B2 (en) | 2005-09-07 | 2015-04-21 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| US9005229B2 (en) | 2005-09-07 | 2015-04-14 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| US9179928B2 (en) | 2005-09-07 | 2015-11-10 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| US7588547B2 (en) | 2005-09-07 | 2009-09-15 | Cabochon Aesthetics, Inc. | Methods and system for treating subcutaneous tissues |
| US9358033B2 (en) | 2005-09-07 | 2016-06-07 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
| US7601128B2 (en) | 2005-09-07 | 2009-10-13 | Cabochon Aesthetics, Inc. | Apparatus for treating subcutaneous tissues |
| US9486274B2 (en) | 2005-09-07 | 2016-11-08 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| US9272124B2 (en) | 2005-12-02 | 2016-03-01 | Ulthera, Inc. | Systems and devices for selective cell lysis and methods of using same |
| US9248317B2 (en) | 2005-12-02 | 2016-02-02 | Ulthera, Inc. | Devices and methods for selectively lysing cells |
| US10548659B2 (en) | 2006-01-17 | 2020-02-04 | Ulthera, Inc. | High pressure pre-burst for improved fluid delivery |
| US10220122B2 (en) | 2007-10-09 | 2019-03-05 | Ulthera, Inc. | System for tissue dissection and aspiration |
| US9039722B2 (en) | 2007-10-09 | 2015-05-26 | Ulthera, Inc. | Dissection handpiece with aspiration means for reducing the appearance of cellulite |
| US8579835B2 (en) | 2008-02-01 | 2013-11-12 | Alma Lasers Ltd. | Apparatus and method for selective ultrasonic damage of adipocytes |
| WO2009095894A3 (fr) * | 2008-02-01 | 2009-12-30 | Alma Lasers Ltd. | Appareil et procédé pour dégradation sélective d’adipocytes par ultrason |
| EP3461438A1 (fr) * | 2009-07-08 | 2019-04-03 | Sanuwave, Inc. | Système de traitement par ondes de chocs intracorporelles et extracorporelles combinées |
| US9044259B2 (en) | 2009-08-07 | 2015-06-02 | Ulthera, Inc. | Methods for dissection of subcutaneous tissue |
| US8900261B2 (en) | 2009-08-07 | 2014-12-02 | Ulthera, Inc. | Tissue treatment system for reducing the appearance of cellulite |
| US8979881B2 (en) | 2009-08-07 | 2015-03-17 | Ulthera, Inc. | Methods and handpiece for use in tissue dissection |
| US8920452B2 (en) | 2009-08-07 | 2014-12-30 | Ulthera, Inc. | Methods of tissue release to reduce the appearance of cellulite |
| US8906054B2 (en) | 2009-08-07 | 2014-12-09 | Ulthera, Inc. | Apparatus for reducing the appearance of cellulite |
| US8900262B2 (en) | 2009-08-07 | 2014-12-02 | Ulthera, Inc. | Device for dissection of subcutaneous tissue |
| US9358064B2 (en) | 2009-08-07 | 2016-06-07 | Ulthera, Inc. | Handpiece and methods for performing subcutaneous surgery |
| US10271866B2 (en) | 2009-08-07 | 2019-04-30 | Ulthera, Inc. | Modular systems for treating tissue |
| US8894678B2 (en) | 2009-08-07 | 2014-11-25 | Ulthera, Inc. | Cellulite treatment methods |
| US9510849B2 (en) | 2009-08-07 | 2016-12-06 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
| US11337725B2 (en) | 2009-08-07 | 2022-05-24 | Ulthera, Inc. | Handpieces for tissue treatment |
| US9757145B2 (en) | 2009-08-07 | 2017-09-12 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| US11096708B2 (en) | 2009-08-07 | 2021-08-24 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
| US9078688B2 (en) | 2009-08-07 | 2015-07-14 | Ulthera, Inc. | Handpiece for use in tissue dissection |
| US10531888B2 (en) | 2009-08-07 | 2020-01-14 | Ulthera, Inc. | Methods for efficiently reducing the appearance of cellulite |
| US10485573B2 (en) | 2009-08-07 | 2019-11-26 | Ulthera, Inc. | Handpieces for tissue treatment |
| WO2011073358A1 (fr) * | 2009-12-16 | 2011-06-23 | Switech Medical Ag | Dispositif destiné à générer un champ ultrasonore et procédé de lypolyse |
| US10603066B2 (en) | 2010-05-25 | 2020-03-31 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
| US20120157888A1 (en) * | 2010-12-17 | 2012-06-21 | Nino Grob | Device for generating an ultrasonic field and method of lypolysis |
| US20140012300A1 (en) * | 2010-12-17 | 2014-01-09 | Switech Medical Ag | Ultrasonic Wave Generator and Method of Lipolysis |
| US11213618B2 (en) | 2010-12-22 | 2022-01-04 | Ulthera, Inc. | System for tissue dissection and aspiration |
| JP2019509111A (ja) * | 2016-03-03 | 2019-04-04 | アルマ レーザー エルティーディー.Alma Lasers Ltd. | ソノトロード |
| KR20180123035A (ko) * | 2016-03-03 | 2018-11-14 | 알마 레이저 엘티디. | 소노트로드 |
| KR102346814B1 (ko) * | 2016-03-03 | 2022-01-03 | 알마 레이저 엘티디. | 소노트로드 |
| US11278745B2 (en) | 2016-03-03 | 2022-03-22 | Alma Lasers Ltd. | Sonotrode |
| WO2017149506A1 (fr) * | 2016-03-03 | 2017-09-08 | Alma Lasers Ltd. | Sonotrode |
| US11642551B2 (en) | 2016-03-03 | 2023-05-09 | Alma Lasers Ltd. | Sonotrode |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0513244A1 (fr) | 1992-11-19 |
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