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WO1992001049A3 - Antigene de surface de cellule cd53 et son utilisation - Google Patents

Antigene de surface de cellule cd53 et son utilisation Download PDF

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Publication number
WO1992001049A3
WO1992001049A3 PCT/US1991/004986 US9104986W WO9201049A3 WO 1992001049 A3 WO1992001049 A3 WO 1992001049A3 US 9104986 W US9104986 W US 9104986W WO 9201049 A3 WO9201049 A3 WO 9201049A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell surface
cloning
mammalian
highly efficient
surface antigens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1991/004986
Other languages
English (en)
Other versions
WO1992001049A2 (fr
Inventor
Brian Seed
Alejandro Aruffo
Martine Amiot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Priority to JP3515602A priority Critical patent/JPH06504186A/ja
Priority to AU85286/91A priority patent/AU658370B2/en
Priority to KR1019930700092A priority patent/KR100206524B1/ko
Priority to CA002087272A priority patent/CA2087272C/fr
Publication of WO1992001049A2 publication Critical patent/WO1992001049A2/fr
Anticipated expiration legal-status Critical
Publication of WO1992001049A3 publication Critical patent/WO1992001049A3/fr
Priority to KR1019997001739A priority patent/KR100229113B1/ko
Priority to KR1019997001740A priority patent/KR100229114B1/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

On a découvert un procédé simple et hautement efficace de clonage d'ADNs complémentaires à partir de banques d'expression mammifère basées sur l'expression transitoire dans des cellules hôtes mammifères. L'invention concerne également de nouveaux vecteurs d'expression permettant l'élaboration hautement efficace de banques d'ADNs complémentaires mammifères. Le procédé de clonage de l'invention ayant été utilisé pour cloner des gènes destinés à des antigènes de surface de cellules de lymphocytes humains, présente une application générale dans le clonage de gènes. On a purifié des antigènes de surface de cellules clonées selon l'invention, et on a déterminé les séquences de nucléotides et d'acides aminés. Ces antigènes présentent une utilité diagnostique et thérapeutique dans des infections d'origine immunitaire chez des mammifères, y compris chez l'homme.
PCT/US1991/004986 1990-07-13 1991-07-15 Antigene de surface de cellule cd53 et son utilisation Ceased WO1992001049A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP3515602A JPH06504186A (ja) 1990-07-13 1991-07-15 Ｃｄ５３細胞表面抗原とその使用
AU85286/91A AU658370B2 (en) 1990-07-13 1991-07-15 CD53 cell surface antigen and use thereof
KR1019930700092A KR100206524B1 (ko) 1990-07-13 1991-07-15 씨디 53 세포 표면 항원 및 그를 암호화하는 재조합 디엔에이
CA002087272A CA2087272C (fr) 1990-07-13 1991-07-15 Antigene de surface des lymphocytes cd53 et son utilisation
KR1019997001739A KR100229113B1 (ko) 1990-07-13 1999-03-02 티엘아이에스에이 세포 표면 항원 및 그를 암호화하는 재조합 디엔에이
KR1019997001740A KR100229114B1 (ko) 1990-07-13 1999-03-02 씨디27세포 표면 항원 및 그를 암호화하는 재조합 디엔에이

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55375990A 1990-07-13 1990-07-13
US553,759 1990-07-13

Publications (2)

Publication Number Publication Date
WO1992001049A2 WO1992001049A2 (fr) 1992-01-23
WO1992001049A3 true WO1992001049A3 (fr) 1993-09-30

Family

ID=24210641

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1991/004986 Ceased WO1992001049A2 (fr) 1990-07-13 1991-07-15 Antigene de surface de cellule cd53 et son utilisation

Country Status (8)

Country Link
EP (1) EP0551301A1 (fr)
JP (3) JPH06504186A (fr)
KR (1) KR100206524B1 (fr)
AU (1) AU658370B2 (fr)
CA (1) CA2087272C (fr)
IE (1) IE912466A1 (fr)
PT (1) PT98326B (fr)
WO (1) WO1992001049A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7132395B1 (en) 1988-09-01 2006-11-07 Bayer Pharmaceuticals Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5316920A (en) * 1992-04-17 1994-05-31 Dana-Faber Cancer Institute, Inc. Lymphocyte activation antigen HB15, a member of the immunoglobulin superfamily
JPH07503024A (ja) * 1992-04-30 1995-03-30 シェリング・コーポレーション トロンボスポンジン−ｃｄ３６相互作用の変調
DE69302276T2 (de) * 1992-07-21 1996-09-19 Isis Innovation Diagnostische Methode
WO1996033217A1 (fr) * 1995-04-19 1996-10-24 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Proteine d'adhesion de cellules, agent immunosuppresseur contenant cette proteine et agent immunosuppresseur renfermant des cellules ainsi induites
US5990299A (en) * 1995-08-14 1999-11-23 Icn Pharmaceuticals, Inc. Control of CD44 gene expression for therapeutic use
WO1997020046A1 (fr) * 1995-11-30 1997-06-05 Schering Corporation Molecule d'adn, antigene tn et molecule d'adhesion appartenant a la superfamille des immunoglobulines
US5863735A (en) * 1997-02-24 1999-01-26 Incyte Pharmaceuticals, Inc. Human transmembrane 4 superfamily protein
US5854022A (en) * 1997-05-13 1998-12-29 Incyte Pharmaceuticals, Inc. Polynucleotides encoding a CD53-like transmembrane protein
US6486299B1 (en) * 1998-09-28 2002-11-26 Curagen Corporation Genes and proteins predictive and therapeutic for stroke, hypertension, diabetes and obesity
EP1006183A1 (fr) * 1998-12-03 2000-06-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Récepteurs Fc recombinantes et solubles
WO2002044342A2 (fr) * 2000-10-18 2002-06-06 The Brigham And Women's Hospital, Inc. Polypeptides ligands de e-selection/l-selectine et methodes d'utilisation associees
WO2005044075A2 (fr) * 2003-09-19 2005-05-19 Diadexus, Inc. Compositions, variantes d'epissures, et procedes se rapportant a des genes et proteines specifiques du sein
EA015584B1 (ru) 2005-03-23 2011-10-31 Генмаб А/С Антитело к cd38 человека и его применение
US8084236B2 (en) 2006-06-02 2011-12-27 Robert Sackstein Compositions and methods for modifying cell surface glycans
NZ576122A (en) 2006-09-26 2012-09-28 Genmab As Anti-cd38 plus corticosteroids plus a non-corticosteroid chemotherapeutic for treating tumors
EP2090320A1 (fr) * 2008-02-15 2009-08-19 Helmholtz-Zentrum für Infektionsforschung GmbH Ligands du marqueur CD27 de surface de cellule tueuse naturelle (NK) et ses utilisations thérapeutiques
WO2011130434A2 (fr) 2010-04-13 2011-10-20 Celldex Therapeutics Inc. Anticorps qui se lient au cd27 humain et utilisations de ceux-ci
SI2580243T1 (sl) 2010-06-09 2020-02-28 Genmab A/S Protitelesa proti humanemu CD38
US9732154B2 (en) 2014-02-28 2017-08-15 Janssen Biotech, Inc. Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
US9603927B2 (en) 2014-02-28 2017-03-28 Janssen Biotech, Inc. Combination therapies with anti-CD38 antibodies
SG11201701867SA (en) 2014-09-09 2017-04-27 Janssen Biotech Inc Combination therapies with anti-cd38 antibodies
PE20171094A1 (es) 2014-12-04 2017-08-07 Janssen Biotech Inc Anticuerpos anti-cd38 para el tratamiento de la leucemia linfoblastica aguda
ES2745153T3 (es) * 2014-12-08 2020-02-27 Us Health Receptores de antígeno quimérico anti-cd70
CA2986594C (fr) 2015-05-20 2025-06-10 Tufts Medical Center Inc Anticorps anti-cd38 pour le traitement de l’amyloïdose à chaînes légères et d’autres tumeurs malignes hématologiques positives à cd38
UA125115C2 (uk) 2015-06-22 2022-01-12 Янссен Байотек, Інк. Спосіб лікування суб'єкта, який має множинну мієлому (мм)
US20170044265A1 (en) 2015-06-24 2017-02-16 Janssen Biotech, Inc. Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38
HRP20220680T1 (hr) 2015-11-03 2022-07-08 Janssen Biotech, Inc. Potkožne formulacije protutijela anti-cd38 i njihove uporabe
US10781261B2 (en) 2015-11-03 2020-09-22 Janssen Biotech, Inc. Subcutaneous formulations of anti-CD38 antibodies and their uses
AU2018359527A1 (en) 2017-10-31 2020-05-07 Janssen Biotech, Inc. Methods of treating high risk multiple myeloma
US20210198374A1 (en) 2018-04-17 2021-07-01 Celldex Therapeutics, Inc. Anti-cd27 and anti-pd-l1 antibodies and bispecific constructs
EP3990015A4 (fr) * 2019-06-27 2023-04-26 Verseau Therapeutics, Inc. Compositions anti-cd53 et procédés de modulation de phénotypes inflammatoires de cellules myéloïdes et leurs utilisations
KR20230161569A (ko) 2022-05-18 2023-11-28 엘지전자 주식회사 옷걸이 및 옷걸이를 구비하는 의류처리장치
KR20230161572A (ko) 2022-05-18 2023-11-28 엘지전자 주식회사 옷걸이 및 옷걸이를 구비하는 의류처리장치
KR20230161570A (ko) 2022-05-18 2023-11-28 엘지전자 주식회사 옷걸이 및 옷걸이를 구비하는 의류처리장치
KR20230161568A (ko) 2022-05-18 2023-11-28 엘지전자 주식회사 옷걸이 및 옷걸이를 구비하는 의류처리장치
KR20230161571A (ko) 2022-05-18 2023-11-28 엘지전자 주식회사 옷걸이 및 옷걸이를 구비하는 의류처리장치

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330191A2 (fr) * 1988-02-25 1989-08-30 The General Hospital Corporation ADN encodant CD40

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330191A2 (fr) * 1988-02-25 1989-08-30 The General Hospital Corporation ADN encodant CD40

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
IMMUNOGENETICS, Vol. 32, No. 4, October 1990, SPRINGER INTERNATIONAL, pages 281-285, ANGELISOVA P. et al., "The Human Leukocyte Surface Antigen CD53 is a Protein Structurally Similar to the CD37 and MRC OX-44 Antigens". *
JOURNAL OF IMMUNOLOGY, Vol. 145, No. 12, 15 December 1990, Baltimore, US, pages 4322-4325, AMIOT M. et al., "Identification and Analysis of cDNA Clones Encoding CD53 -A Pan Leukocyte Antigen Related to Membrane Transport Proteins". *
KNAPP W. et al., "Leucocyte Typing IV -White Cell Differentiation Antigens-", 1989, OXFORD UNIVERSITY PRESS, WALTON STREET, OXFORD, GB, "N13 Cluster Report : CD53", pages 674-678. *
KNAPP W. et al., "Leucocyte Typing IV -White Cell Differentiation Antigens-", 1989, OXFORD UNIVERSITY PRESS, WALTON STREET, OXFORD, GB, "N13.1 Reactivity of the Non Lineage/NK Panel Antibodies with Purified Antigens CD45, CD43, CD44 and CD18 and Three 'Novel' Antigens MEM-43, MEM-53 and MEM-102", pages 678-680. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7132395B1 (en) 1988-09-01 2006-11-07 Bayer Pharmaceuticals Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)

Also Published As

Publication number Publication date
PT98326B (pt) 1999-01-29
IE912466A1 (en) 1992-01-15
AU8528691A (en) 1992-02-04
JPH06504186A (ja) 1994-05-19
EP0551301A1 (fr) 1993-07-21
CA2087272C (fr) 2005-10-11
AU658370B2 (en) 1995-04-13
JP2003038179A (ja) 2003-02-12
KR100206524B1 (ko) 1999-07-01
PT98326A (pt) 1992-06-30
WO1992001049A2 (fr) 1992-01-23
CA2087272A1 (fr) 1992-01-14
JP2001157592A (ja) 2001-06-12

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