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WO1990007350A1 - Seringue hypodermique jetable - Google Patents

Seringue hypodermique jetable Download PDF

Info

Publication number
WO1990007350A1
WO1990007350A1 PCT/NO1990/000001 NO9000001W WO9007350A1 WO 1990007350 A1 WO1990007350 A1 WO 1990007350A1 NO 9000001 W NO9000001 W NO 9000001W WO 9007350 A1 WO9007350 A1 WO 9007350A1
Authority
WO
WIPO (PCT)
Prior art keywords
cannula
hypodermic syringe
piston rod
syringe according
actuating member
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/NO1990/000001
Other languages
English (en)
Inventor
Odd Gerhard MÜLLER
Per Gunnar Werner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO1990007350A1 publication Critical patent/WO1990007350A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/322—Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
    • A61M5/3234—Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user

Definitions

  • hypodermic syringes represent a serious risk of infection in various ways, including repeated use among drug addicts.
  • Significant efforts have been made all over the world in an attempt to design hypodermic syringes which cannot be used more than once.
  • An example of designs which have been tried is based on the breaking of the piston rod of the syringes when an injection has been completed, and another example simply consists therein that the user himself can actively retract the cannula into the syringe after the injection.
  • these and other solutions attempted are insufficient in relation to the risk of infection represen ⁇ ted by an infected syringe or cannula tip.
  • An object of this invention is to provide a hypodermic syringe for use only once and with- a substantially complete elimination of the risk of infection which can arise from abuse of syringes or from inadvertant perforation of the skin during handling or contact with a used syringe.
  • the invention takes as a basis the form of a hypodermic syringe for injecting a liquid into body tissue, which comprises a cylindrical main part, a piston with an associated piston rod, an actuating member at the free end of the piston rod, and a cannula for liquid injection when the piston is pressed down by means of the actuating member.
  • the cannula in the first place consists therein that the cannula is adapted to be retractable into the main part, but is retained in a normal condition against such retraction by means of a releasable blocking member, that there is provided drive means for effecting said retraction, and that a releasing device is adapted to release the blocking member on cessation of pressure on the actuating member after an initiated injection.
  • the cannula including the pointed tip thereof will immediately disappear into the main part of the syringe as soon as the user's finger is removed from the actuating member, for example a push button on the piston rod.
  • the syringe is automatically rendered harm ⁇ less, not only as soon as the injection is completed, but also immediately in the case of an interrupted injection.
  • the design described here will also prevent the user from putting the automatic security system of the syringe out of operation.
  • the syringes according to the invention may be utilised in the same manner as earlier commonly known hypodermic syringes as regards filling, venting, applying and injecting.
  • Fig. 1 in longitudinal section shows a first embodi ⁇ ment of the hypodermic syringe according to the invention in its normal or usual condition of use
  • Fig. 2. shows in a similar section the same syringe as in fig. 1 after having been rendered harmless by retrac ⁇ tion of the cannula into the main part of the syringe,
  • Fig. 3 shows at an enlarged scale certain details of a releasing device incorporated in the syringe of figs. 1 and 2,
  • Fig. 4 shows at an enlarged scale other details of the releasing device
  • Fig. 5 shows a second and more preferred embodiment of the syringe according to the invention, in longitudinal section,
  • Fig. 6 shows an enlarged sectional view of the lower portion of the syringe in fig» 5
  • Fig. 7 shows the details at one end of a pulling element provided between the releasing device and the blocking member in the syringe shown in fig. 5,
  • Fig. 8 shows important details at the opposite end of the pulling element
  • Figs. 9 - 12 in enlarged cross-sectional view show the releasing device and the actuating member at the top of the syringe according to fig. 5 in various steps of operation
  • Figs. 13A-D show an additional embodiment of the releasing device in various steps of operation
  • Fig. 14 shows in plane view a membrane element incorporated into the device in figs. 13A-D,
  • Fig. 15 can be considered as an enlarged cross- section of the lower half of the syringe in fig. 5, with retracted cannula and a specific sealing element at the lower end or opening,
  • Fig. 16 shows the lower portion of the syringe in fig. 15 when the sealing element has acquired its final shape
  • Fig. 17 in an enlarged cross-sectional view shows the lower portion of a syringe in its normal condition, having specific design features associated with a sealing element, and
  • Fig. 18 shows the lower portion of a syringe as in fig. 17 but with its cannula retracted.
  • the hypodermic syringe shown in figures 1 and 2 comprises a main part in the form of an outer tube 15 and an inner tube 16 with an intermediate piston 4 and an associa ⁇ ted tubular piston rod 11, the upper free end of which is provided with an actuating member in the form of a push button 9.
  • a cannula 8 projects through a lower opening 21.
  • the cannula 8 can be retracted into the syringe main part 15, i.e. more particularly into the inner tube 16, but in its normal position as illustrated in fig. 1, is blocked against inward retraction by means of a blocking member in the form of an ampulla 5 filled with a pressurised medium and retained against an abutment element in the form of a flange 17 in the interior of the tube 16.
  • a compression spring 6 constitutes drive means urging the cannula 8 in the upwards direction in the figure, i.e. against the under side of the ampulla 5.
  • a disc 18 or a similar engagement piece for this purpose is attached to the upper end of the cannula 8. The disc 18 is shaped so as to be able to pass through the opening delimited by the flange 17.
  • Puncture or destruction of the ampulla 5 will release the cannula 8 for movement upwards and into the tube 16 under the influence of the compression spring 6.
  • This release of the blocking takes place by means of a needle 3 which can be shot downwards from its releasing device at the top of the piston rod 11, the needle 3 being brought to move by an upper spring 10 after releasing.
  • a cone 13 At the top of the tube 16 there is formed a cone 13 with an enlarged flat bottom 14, the cone serving to catch the point of the needle 3 and guide it in a correct direction against the ampulla 5 even if the whole of the needle should initially be located above the cone-shaped opening 13.
  • the releasing device for the needle 3 as shown at an enlarged scale in figs. 3 and 4 with main components 1 and 2, can be considered similar to the conventional activating mechanism in ballpoint pens.
  • a round plate 2 is mounted at the upper portion of the needle 3 and is adapted to co ⁇ operate with notches in the interior of a sleeve-shaped part 1, lb which accommodates the spring 10. When the plate 2 is rotated incisions through it will make it possible for the plate, and thereby the needle 3, to move downwards under the influence of the spring 10.
  • This release takes place when the actuating button 9 is depressed for injection and is then released, which can for example be the case when the injection has been completed and the syringe is empty, or when the user attempts to change hands on the syringe, or if two drug addicts try to share a dose from the same syringe.
  • the syringe is provided with a top plate 12 which among other things makes it impossible to disassemble the syringe.
  • Figure 2 shows the syringe after use, i.e. with the blocking member in the form of the ampulla 5 destroyed and both springs 6 and 10 having performed their function.
  • the cannula 8 has been retracted into the inner tube 16 and has stopped against the cone bottom 14 with the point of the cannula located at or immediately inside the opening 21 at the lower end of the syringe.
  • a sealing member 20 about the cannula 8 there can with advantage be provided a sealing element which prevents leakage along the cannula 8 out through the opening 21.
  • the hypodermic syringe thus has been rendered harmless and can never be used again. Remaining liquid in the space 19 in front of the piston 4 cannot leak out.
  • a main part 32 an inner tube 33, an annular piston 31 adapted to move between these and an associated piston rod 34.
  • injection liquid from the space 38 in front of the piston 31 can be pressed out into a cannula 37 through channels 33b and 36b, provided respectively at the bottom of the main part 32 and in a mounting member 36 for the cannula 37 which penetrates through an opening 32a at a projecting bottom portion of the main part 32.
  • the tubular parts 32 and 33 with the associated annular piston 31 can have circular, hexagonal or other cross-sectional shapes.
  • the piston rod 34 is enlarged and shaped so as to accommodate a portion of a releasing device 40.
  • This device is also partly enclosed by an actuating member in the form of a flexible cap 35 which is made to be elastically resilient to a compressive load, for example from a user's thumb.
  • a plug-shaped part 41 of the releasing device is pressed into the upper end portion of the piston rod 34 and serves an important function which will be explained more closely in connection with figures 9 - 12 below.
  • a pulling element 42 is extended centrally down through the piston rod and the inner tube 33 to a blocking member on the mounting 36.
  • the releasing device 40 has an engagement member 45 adapted to co-operate with toothing or the like on the pulling * element 42.
  • Figure 6 shows in more detail the mounting or blocking member 36 the top of which is attached to the lower end of the pulling element 42 and forms a plate- or yoke-like transverse piece with edges 36a adapted to abut against, and being blocked by flanges 33a in the interior of the inner tube 33. Accordingly these flanges constitute projecting small abutments which in the normal condition secure against any movement of the blocking and mounting member 36 upwards through the inner tube 33.
  • the cannula 37 in this normal condition or position is located so as to project from the main part 32 ready for normal use, i.e. an injection operation.
  • a compression spring 39 is provided in the tube part 33 between the bottom thereof and shoulders around the outer periphery of the upper enlarged portion of the blocking and mounting member 36.
  • the spring 39 seeks to push this member upwards, but this is without any effect as long as the blocking between the co-operating blocking elements 36a and 33a is present.
  • This blocking effect is adapted to be removed at the occurrence of only a relatively weak upwardly directed tensional force in the pulling element 32, as such a force will deform the transverse piece of the member 36 between the abutment flanges 33a, i.e. by a certain bulging upwards of the middle portion and thereby a reduction of the lateral dimension.
  • the projections 36a can move past the flanges 33a, and the spring 39 with a comparatively large force may throw not only the mounting member 36 as a whole, but also the pulling element 42 upwards through the inner tube 33.
  • the cannula 37 is retracted into the main parts 32-33 of the syringe through the lower opening 32a. This retractive movement continues until the whole cannula 37 has been displaced through the opening 32a and is brought into a secure and protected position inside the main parts of the syringe.
  • Figure 7 shows in elevation the design of the blocking and mounting member 36 with blocking projections 36a and the pulling element 42.
  • This string-shaped pulling element can be moulded as one piece with the mounting member 36 and is flexible, but has a certain stiffness which makes it possible to push it upwards through the inner tube part 33 and the piston rod 34 during the upward movement caused by the spring 39, as explained above.
  • Figure 8 shows in elevation the upper end of the pulling element 42, the release member 41 and a portion of the actuating member 35 which is formed by an elastic cap.
  • a release arm 35a being directed downwards and provided with two hooks 47a and 47b adapted to co-operate with an oppositely directed hook 41a on the moveable engagement piece 45 which is incorporated in the release member 41.
  • the hook 47b is ready to engage the hook 41a.
  • the engagement piece 45 of the releasing device is set into an activated condition when there is exerted a pressure e.g. a finger on the cap-shaped actuating member 35, as the respective hooks 47a and 47b are brought into an active position in relation to the hook 41a (fig. 8).
  • a pressure e.g. a finger on the cap-shaped actuating member 35
  • the elastic restoration thereof will bring the engagement piece 45 with projections 45a to engage the toothing of the toothing element 42 and cause an initial displacement which in its turn leads to complete releasing and retraction as illustrated in figs. 9-12.
  • FIGS. 13A-D and figure 14 show an alternative and simpler embodiment of the releasing device.
  • a cap-shaped and elastic actuating member 55 which is attached to an extension of the piston rod 54 and has a release arm 53 serving a quite similar function to the release arm 35a in fig. 8.
  • a pulling element 52 having a hook-like toothing.
  • An essential component in this embodiment is a membrane 51 mounted around the inner circumference of the piston rod 54.
  • the membrane 51 has a hole 51a for the release arm 53 and another opening 51b through which the pulling element 52 is extended.
  • a tongue 51c directed towards the opening 51b is adapted to co-operate with the toothing of the pulling element 52.
  • the membrane 51 bulges downward and a first hook-like projection 53b on the release arm 53 is located on the under side of the membrane.
  • the release arm 53 On depressing the cap 55 as shown in fig. 13B, i.e. by normal use of the syringe during an injection, the release arm 53 is displaced downwards and the second hook 53a thereon passes through the hole 51a and takes a position at the underside of the membrane. Thereby the releasing device is activated.
  • the hook 53a will move the membrane 51 towards a neutral position at the same time as the tongue 51cengages the toothing of the pulling element and exerts an initial tensional force on the pulling element.
  • the membrane 51 will quickly snap through or be transformed from a condition of bulging downwards to a condition of bulging upwards and thereby exert a significant tensional force in the pulling element, so that a quick and strong upward movement of the pulling element 52 is obtained.
  • the blocking member is released as described above, in particular in connection with fig. 6, and the pulling element 52 is pushed into a circular chamber 56 in the form of a coil.
  • the clamped membrane element 51 thus preferrably covers substantially the whole interior cross-sectional area of the piston rod 54 and has two stable positions bulging out to respectively opposite axial directions within the piston rod (fig. ⁇ 3A and 13D) .
  • the function described will be attained.
  • a hypodermic syringe having an automatic retraction of the cannula after use, as described above, will reduce to a very substantial degree the risks of spreading infection and the like. It can occur, however, that for example children put a used syringe in the mouth and suck. Then the child may be infected by some of the substance which still may be present in or on the syringe, e.g. a drug, and can be contaminated by infectious substances which may be located within and around the opening for the cannula.
  • a sealing element 60 arranged to be releasable in relation to the opening for retracting the cannula into the syringe.
  • a sealing element can be adapted to be released by this retraction, for the purpose of enclosing the cannula point in the completely retracted position and besides, preferrably to seal the opening completely.
  • Figure 15 shows in more detail such a sealing element 60a in the situation where the cannula 67 is fully retracted and the point thereof is located inside the opening 61.
  • the sealing element 60a can be an elastic material which in the situation shown will in the first place tightly enclose the point of the cannula and in the second place expand or be subjected to a change of shape so that the whole space around the cannula point and the opening 61 will be filled.
  • Figure 16 shows this final condition of the sealing element 60b, which has been partially extruded through the opening 61 so that this has become more or less completely sealed.
  • a suitable material for this sealing element may be polyurethane foam which is easily shaped and can expand or alternatively contract to a sufficient degree for effect ⁇ ively sealing the opening.
  • a foam-like porous material will also be able to absorb injection liquid or the like, of which remains usually are present in the syringe itself and in the cannula.
  • a cellulose-basefd material or textile fibres may be able to have a similar effect by giving a relatively efficient sealing by swelling or taking up liquid or moisture.
  • polyurethane foam as mentioned, or other cellular materials may be mixed with a substance which reacts chemically when brought into contact with water or another liquid, and which brings the cells to swell or foam and to form a hard surface when the chemical reaction has been terminated.
  • adhesive technology from which polyurethane and epoxy adhesives may be mentioned as examples.
  • Adhesives of this type are available in which the hardening agent is encapsuled in microscopic spheres which break up on light mechanical influence so that the hardening agent will come into contact with the adhesive substance and the surrounding sphere particles. This starts a process which will spread so that the whole mass gradually will be transformed into a rigid adhesive substance.
  • the sealing element for the cannula point and opening 61 in fig. 15 can be based on such materials or types of adhesive. Further in this connection it is possible to combine such materials with agents for chemically disinfecting the area around the lower portion of the syringe, in particular around the opening 61.
  • Disinfec ⁇ tant's of interest may be included in liquid or solid form.
  • the agent can be activated by mechanical influence or in a similar manner and, besides, the disinfectant may be mixed with the activating liquid utilised for the foaming and hardening as explained above.
  • a mounting or a supporting piece 66 for the cannula 67a is provided with activating elements 66d such as lugs or hooks adapted to .activate or release a sealing element 60c mechanically upon retraction of the cannula 67a through the opening 61a.
  • activating elements 66d such as lugs or hooks adapted to .activate or release a sealing element 60c mechanically upon retraction of the cannula 67a through the opening 61a.
  • interior ribs 69 which keep the sealing element in place.
  • Figure 18 shows the sealing element 60c after swelling or forming so as to result in the desired sealing effect.
  • This cannula point is provided with a removable filter tip consisting of a sleeve ⁇ like clamp 71 adapted to co-operate with the cannula dimension concerned, and a filter material 72 at the end of the sleeve or clamp.
  • a removable filter tip consisting of a sleeve ⁇ like clamp 71 adapted to co-operate with the cannula dimension concerned, and a filter material 72 at the end of the sleeve or clamp.
  • a hypodermic syringe according to the present invention can be designed with various modifica ⁇ tions in relation to what is described above with reference to the drawings, and moreover it is clear that a variety of materials may be employed. It is preferred, however, to manufacture the parts of the syringe from plastic materials in order to make possible a fully automatic, efficient and inexpensive production.
  • the plastic material in the region of the syringe tip can be so chosen that it will be destroyed or atomised by heating, without the cannula being thereby fixed by fusion in its normal position. Attempts to make the automatic retraction function inoperative by such heating, therefore, will not be successful.
  • Syringes according to the invention can be supplied with ready mounted cannulas or with separate cannulas intended for mounting by the user himself. Sealing elements as discussed particularly with reference to figs. 15-18 can also be provided in hypodermic syringes based on possible different means for retracting the cannula, than described here.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Environmental & Geological Engineering (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La seringue hypodermique jetable décrite, qui sert à l'injection de liquides dans des tissus corporels, comprend une partie princiale cylindrique (32), un piston (31) avec tige de piston associée (34), un élément actuateur (35) placé à l'extrémité libre de la tige de piston, ainsi qu'une canule (37) servant à l'injection du liquide lors de la compression du piston par l'élément actuateur. La canule (37) est destinée à se rétracter dans la partie principale (32). En position normale, elle est toutefois protégée contre cette rétraction par un élément de blocage débloquable (36a). Un organe d'entraînement (39) est prévu pour permettre cette rétraction et un dispositif de déblocage (40, 41) sert à débloquer l'élément de blocage (36a) lors du relâchement de la pression s'exerçant sur l'élément actuateur, une fois l'injection commencée.
PCT/NO1990/000001 1989-01-04 1990-01-02 Seringue hypodermique jetable Ceased WO1990007350A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO89890027A NO890027L (no) 1989-01-04 1989-01-04 Injeksjonssproeyte.
NO890027 1989-01-04

Publications (1)

Publication Number Publication Date
WO1990007350A1 true WO1990007350A1 (fr) 1990-07-12

Family

ID=19891594

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NO1990/000001 Ceased WO1990007350A1 (fr) 1989-01-04 1990-01-02 Seringue hypodermique jetable

Country Status (5)

Country Link
CN (1) CN1043876A (fr)
AU (1) AU4821190A (fr)
NO (1) NO890027L (fr)
WO (1) WO1990007350A1 (fr)
ZA (1) ZA9030B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991003269A1 (fr) * 1989-08-28 1991-03-21 Townsend Controls Pty. Ltd. Seringue de securite
WO1991004065A1 (fr) * 1989-09-18 1991-04-04 Assumpsit No. 102 Pty. Ltd. Seringue
WO1993000950A1 (fr) * 1991-07-05 1993-01-21 Mauro Ghigo Seringue jetable a securite
WO1996004030A1 (fr) * 1994-08-05 1996-02-15 Paola Danesi Seringue a usage unique et a aiguille retractable

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2155015C1 (ru) * 1999-11-23 2000-08-27 Федеральное государственное унитарное предприятие Конструкторское бюро химавтоматики Пневматический безыгольный инъектор
CN105722539B (zh) * 2013-11-13 2021-01-15 豪夫迈·罗氏有限公司 辅助式手动注射装置和方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4747831A (en) * 1987-04-29 1988-05-31 Phase Medical, Inc. Cannula insertion set with safety retracting needle
US4838869A (en) * 1987-08-29 1989-06-13 Allard Edward F Retractable needle syringe
DK156414B (da) * 1987-07-13 1989-08-21 Gerda Ingrid Maria Gaarde Injektionssproejte med kanyle, der kan indtraekkes og fastlaases i sproejten

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4747831A (en) * 1987-04-29 1988-05-31 Phase Medical, Inc. Cannula insertion set with safety retracting needle
DK156414B (da) * 1987-07-13 1989-08-21 Gerda Ingrid Maria Gaarde Injektionssproejte med kanyle, der kan indtraekkes og fastlaases i sproejten
US4838869A (en) * 1987-08-29 1989-06-13 Allard Edward F Retractable needle syringe

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991003269A1 (fr) * 1989-08-28 1991-03-21 Townsend Controls Pty. Ltd. Seringue de securite
WO1991004065A1 (fr) * 1989-09-18 1991-04-04 Assumpsit No. 102 Pty. Ltd. Seringue
WO1993000950A1 (fr) * 1991-07-05 1993-01-21 Mauro Ghigo Seringue jetable a securite
WO1996004030A1 (fr) * 1994-08-05 1996-02-15 Paola Danesi Seringue a usage unique et a aiguille retractable

Also Published As

Publication number Publication date
NO890027L (no) 1990-07-05
ZA9030B (en) 1990-10-31
CN1043876A (zh) 1990-07-18
NO890027D0 (no) 1989-01-04
AU4821190A (en) 1990-08-01

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