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WO1988000845A1 - Dispositif (appareil) de traitement de fractures d'os, en particulier de pseudarthroses - Google Patents

Dispositif (appareil) de traitement de fractures d'os, en particulier de pseudarthroses Download PDF

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Publication number
WO1988000845A1
WO1988000845A1 PCT/DE1987/000343 DE8700343W WO8800845A1 WO 1988000845 A1 WO1988000845 A1 WO 1988000845A1 DE 8700343 W DE8700343 W DE 8700343W WO 8800845 A1 WO8800845 A1 WO 8800845A1
Authority
WO
WIPO (PCT)
Prior art keywords
circuit
transistor
direct current
bone
circuits
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DE1987/000343
Other languages
German (de)
English (en)
Inventor
Alaa El-Din Otaify
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ihaz Industrie- und Handels-Ausstellungs-Zentr
Original Assignee
Ihaz Industrie- und Handels-Ausstellungs-Zentr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ihaz Industrie- und Handels-Ausstellungs-Zentr filed Critical Ihaz Industrie- und Handels-Ausstellungs-Zentr
Publication of WO1988000845A1 publication Critical patent/WO1988000845A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems

Definitions

  • Apparatus (device) arthrosis for the treatment of bone fractures, in particular for the treatment of Pseud- ⁇ .
  • the constant electrical potentials are increased in the broken parts of a bone; they gradually decrease with progressive bone healing and fracture healing until after the
  • the present invention is based on the following principal
  • Procure bones in such a way that they form positive and negative electrical charges, as well as dynamic (piezoelectric) and constant (bioelectric) voltages (potentials). Since the negative charges lead to cellular activities (interactions), fixing (determining) and generating (generating) these 10 charges on the incurable bone fracture can lead to cell stimulation, which then helps the fracture to heal.
  • the object on which the present invention is based is to provide a device or a device of the generic type, with which, on the basis of the above knowledge, the healing of broken bones in humans is made possible in the first place under certain circumstances.
  • the dose of the negative electrical charges which is necessary for the treatment of incurable fractures, is defined, fixed and kept constant; the appropriate shape for the electrical sign is selected at the same time.
  • the biological activities of the cells are investigated using isotopes, as is their resonance for the external electrical charges).
  • the device maintains the appropriate dose of the electrical charges without reduction, in spite of the change in temperature in the human body. per due to the bone formation on the negative poles. (This is achieved by means of a self-regulating *, the transistor circuit which maintains the desired current strength during the three-month treatment period).
  • the device guarantees the uninterrupted (constant) supply of the appropriate dose of electrical charges during the treatment period. This is done by means of an acoustic and an optical alarm system in order to warn the patient acoustically if the current at one pole (at any negative pole) fails due to an interruption in a direct current circuit, and to signal the patient to display a light cell belonging to the optical alarm system 5, which is the fault location.
  • the generated (generated) current strength is measured at all four negative poles.
  • Each of the four poles can be switched on separately by an external o avometer.
  • the device is equipped with an internal micro-avometer to separate the generated current 5 for each negative pole and directly by four
  • FIG. 1 shows a complete device for the treatment of incurable bone fractures by using electrical stimulation of the bone cells by means of low-° (light) direct current;
  • FIG. 2 shows the electrical circuit arrangements or circuits used in the device according to FIG. 1;
  • FIG. 3 shows an application example for a device according to FIG. 1 .
  • Fig. 1 shows the complete structure of the electrical rule
  • Device for stimulating bone cells It consists of a rectangular housing box 1 with the device dimensions - length x width x height approximately 10 x 6 x 2.5 cm (centimeters). In the upper part of the housing, the device contains a micro avometer (measuring device for current and
  • the micro-avometer has a display which is subdivided for the ranges 1 to 100 micro-amperes and 1 to 10 volts; the ikro-Avometer is marked with the reference symbol w.
  • the device contains a display H which tests (monitors) the battery during operation.
  • the device comprises an acoustic alarm system (loudspeaker) C and four optical (lighting) control systems.
  • the acoustic alarm system warns the patient when one of the four direct current circuits which generate the direct current is interrupted.
  • One of the light-emitting diodes 15, 16, 17, 18 (compare diodes D_, according to FIG. 2) of a light-emitting diode line B indicates the point of failure or the interrupted direct current circuit.
  • connecting lines 4 Five connecting lines (wires) 4 are connected to the device.
  • One of these connecting lines 4 is the positive pole (is connected to the positive pole), which is connected to a thin rectangular anode plate 3 et ⁇ 5 w with the dimensions 4 x 2.5 cm. This sheet 3 is placed and fixed on the patient's skin when the device is used.
  • the other connecting lines 4- are the negative poles (are connected to the negative poles); these lines are connected to a Kirschner needle (Kirschner wire) 2 with a thickness of approximately 1.2 mm (millimeters).
  • This Kir ⁇ schner needle is covered with an insulating jacket made of polytetrafluoroethylene (trade name TEFLON), up to a distance of about 1 cm from the tip; this tip is inserted (inserted) at the bone fracture (in the area of the bone fracture).
  • TEFLON polytetrafluoroethylene
  • the device is operated by a (alkaline) battery with approximately 9 volt operating voltage, which has its special place in the device and which has a special one
  • Cover on the back of the device (the housing) is replaceable.
  • FIG. 2 shows the electrical circuits which explain (disclose) the complete circuit structure of the device according to FIG. 1. This circuit consists of four
  • Transistor circuits A four transistor circuits B, one circuit C and one circuit D.
  • the circuit A forms the direct current source and consists of a variable resistor M- (with 5 approximately 100 kohm) and a transistor 1 (for example of the type BF 244; this is an NPN silicon transistor for example from the company Texas Instruments or Valvo), which are connected to an (alkaline battery S with a battery voltage of about 9 volts.
  • This circuit o A generates a direct current of about 20 microamps, regardless of a change in resistance in the human body (of the patient) due to the formation of bones in the region of the negative poles This is achieved by the self-regulating properties with regard to keeping the desired (required) current constant with the transistor T 1 (of the BF 244 type).
  • Circuit B forms the optical control system. It consists of a transistor _ (for example of the type BC 1o8; this is an NP transistor for low-frequency pre and driver stages, for example from the Siemens company) as a changeover switch (switching transistor), Current passage (current flow) in circuit B allows (opens) when the corresponding (coupled) circuit A of the direct current source is interrupted.
  • the circuit B also consists of two resistors M 2 5 and M- 2 (both about 47o Ohm), and a transistor T (for example of the type BC 1o9; this is an NPN transistor for low-frequency pre- and driver stages, for example from Siemens).
  • This group (this circuit part) is connected to a light-emitting diode D 1 (light cell) o which lights up in the event of an interruption in the assigned circuit A and indicates this (to the faulty circuit).
  • Circuit C forms the acoustic alarm system. It warns acoustically in the event of an interruption of any of the four circuits A and consists of a transistor T 1 (for example of the type B 1 C 10 7; this is an NP transistor for low-frequency preliminary and driver stages for Example from Siemens), two serially connected diodes D 2 0 and O _ and an automatic o L autton (acoustic generator) G, which is an acoustic
  • the circuit D serves as a test circuit for checking the transistor operation (the transistor functions) and consists of two resistors M, (with about 47o Ohm) 5 and H r (with about 6o kOhm), a basis (one base) for the transistor mounting K and a light emitting diode
  • This test circuit D is used for simple maintenance and testing of the entire device according to FIG. 1, without having to resort to a specialist.
  • the circuit arrangement shown in Fig. 2 also shows the arrangement of the micro-Avo eters W, as well as the display H for the B tterie voltage and the group of four switches 1o, 11, 12, 13 of the switching unit, which indicates the current intensity generated Measure each negative pole o separately, and the changeover switch 0, which measures the difference in the battery voltage during use (during operation).
  • FIG. 3 shows the use of the device according to the invention for the treatment of broken bones, in particular of so-called pseudarthroses, with regard to the surgical handling.
  • FIG. 3 shows a fracture of a bone to which the four cathodes 2 of the device are attached or implanted.
  • These cathodes 2 are each implanted in pairs on the end faces of the 5 break point, specifically obliquely to these end faces; the cathodes 2 are inserted so far through cannulas guided through the patient's flesh adjacent to the fracture that the tips of the cathodes 2 protrude in the free area between the bones to be connected; these tips are the areas left free when the cathodes are encased.
  • the clamping connection boxes 5 are fixed between the cathodes 2 and the connecting lines 4 on the surface of the broken limb or bone, that is to say on the skin.
  • the connecting lines 4 themselves then lead to the device, which the patient can conveniently insert into the pocket due to the minimal dimensions;
  • the device can also be fixed with a strap.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)

Abstract

Un dispositif de traitement de fractures incurables d'os, en particulier de pseudarthroses, par stimulation électrique des cellules osseuses avec un courant continu d'environ 20 micro-ampères, comprend un logement (1) avec un avomètre (W) connecté au pôle négatif et qui mesure séparément la densité des courants générés à chaque pôle. Une batterie échangeable dont le fonctionnement est contrôlé pendant son utilisation fournit l'énergie électrique au circuit. Un système acoustique d'avertissement (C) et un système optique de contrôle (B) sont intégrés afin d'assurer une surveillance continue de l'état de fonctionnement de l'appareil. Le circuit comprend quatre circuits (N) générateurs de courants continus qui sont appliqués à la partie fracturée de l'os à guérir par des raccords d'électrode (2, 4). Un raccord supplémentaire d'anode (3, 4) est posé sur la peau du patient afin de fermer le circuit entre l'anode (3) et les cathodes négatives (2) situées dans la zone de la fracture. On a traité avec grand succès avec cet appareil des fractures d'os considérées jusqu'à aujourd'hui comme incurables, en particulier des pseudarthroses.
PCT/DE1987/000343 1986-08-07 1987-08-05 Dispositif (appareil) de traitement de fractures d'os, en particulier de pseudarthroses Ceased WO1988000845A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EG498/86A EG17822A (en) 1986-08-07 1986-08-07 Direct current(dc)bone growth stimulator for treatment of pseudarthroses
EG498/86 1986-08-07

Publications (1)

Publication Number Publication Date
WO1988000845A1 true WO1988000845A1 (fr) 1988-02-11

Family

ID=8163007

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1987/000343 Ceased WO1988000845A1 (fr) 1986-08-07 1987-08-05 Dispositif (appareil) de traitement de fractures d'os, en particulier de pseudarthroses

Country Status (3)

Country Link
EP (1) EP0291512A1 (fr)
EG (1) EG17822A (fr)
WO (1) WO1988000845A1 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5003965A (en) * 1988-09-14 1991-04-02 Meditron Corporation Medical device for ultrasonic treatment of living tissue and/or cells
US5762616A (en) * 1996-03-15 1998-06-09 Exogen, Inc. Apparatus for ultrasonic treatment of sites corresponding to the torso
US5904659A (en) * 1997-02-14 1999-05-18 Exogen, Inc. Ultrasonic treatment for wounds
US6932308B2 (en) 2000-10-25 2005-08-23 Exogen, Inc. Transducer mounting assembly
US7108663B2 (en) 1997-02-06 2006-09-19 Exogen, Inc. Method and apparatus for cartilage growth stimulation
US7211060B1 (en) 1998-05-06 2007-05-01 Exogen, Inc. Ultrasound bandages
US7410469B1 (en) 1999-05-21 2008-08-12 Exogen, Inc. Apparatus and method for ultrasonically and electromagnetically treating tissue
US7429248B1 (en) 2001-08-09 2008-09-30 Exogen, Inc. Method and apparatus for controlling acoustic modes in tissue healing applications
US7429249B1 (en) 1999-06-14 2008-09-30 Exogen, Inc. Method for cavitation-induced tissue healing with low intensity ultrasound

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2180666A1 (fr) * 1972-04-17 1973-11-30 Sybron Corp
US4175565A (en) * 1977-06-22 1979-11-27 Oratronics, Inc. Method and apparatus for stimulating osteogenic activity in bone structure adjacent a dental implant
EP0086550A1 (fr) * 1982-01-18 1983-08-24 Sutter Biomedical Inc, Dispositif portatif et procédé de guérison des os continue autoindicatifs
US4600010A (en) * 1984-10-04 1986-07-15 Biolectron, Inc. Electric stimulator and test instrument therefor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2180666A1 (fr) * 1972-04-17 1973-11-30 Sybron Corp
US4175565A (en) * 1977-06-22 1979-11-27 Oratronics, Inc. Method and apparatus for stimulating osteogenic activity in bone structure adjacent a dental implant
EP0086550A1 (fr) * 1982-01-18 1983-08-24 Sutter Biomedical Inc, Dispositif portatif et procédé de guérison des os continue autoindicatifs
US4600010A (en) * 1984-10-04 1986-07-15 Biolectron, Inc. Electric stimulator and test instrument therefor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
The Journal of Bone and Joint Surgery, Band 63-A, Nr. 1, Januar 1981, (Edinburgh, GB), C.T. BRIGHTON et al.: "A Multicenter study of the Treatment of Non-Union with Constant direct Current", seiten 2-13 siehe seite 3, absatz "Electrical Apparatus" *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5003965A (en) * 1988-09-14 1991-04-02 Meditron Corporation Medical device for ultrasonic treatment of living tissue and/or cells
US5762616A (en) * 1996-03-15 1998-06-09 Exogen, Inc. Apparatus for ultrasonic treatment of sites corresponding to the torso
US7108663B2 (en) 1997-02-06 2006-09-19 Exogen, Inc. Method and apparatus for cartilage growth stimulation
US5904659A (en) * 1997-02-14 1999-05-18 Exogen, Inc. Ultrasonic treatment for wounds
US6190336B1 (en) 1997-02-14 2001-02-20 Exogen, Inc. Ultrasonic treatment for wounds
US6273864B1 (en) 1997-02-14 2001-08-14 Exogen, Inc. Ultrasonic treatment for wounds
US6685656B1 (en) 1997-02-14 2004-02-03 Exogen, Inc. Ultrasonic treatment for wounds
US7628764B2 (en) 1997-02-14 2009-12-08 Exogen, Inc. Ultrasonic treatment for wounds
US7211060B1 (en) 1998-05-06 2007-05-01 Exogen, Inc. Ultrasound bandages
US7410469B1 (en) 1999-05-21 2008-08-12 Exogen, Inc. Apparatus and method for ultrasonically and electromagnetically treating tissue
US7429249B1 (en) 1999-06-14 2008-09-30 Exogen, Inc. Method for cavitation-induced tissue healing with low intensity ultrasound
US6932308B2 (en) 2000-10-25 2005-08-23 Exogen, Inc. Transducer mounting assembly
US7429248B1 (en) 2001-08-09 2008-09-30 Exogen, Inc. Method and apparatus for controlling acoustic modes in tissue healing applications

Also Published As

Publication number Publication date
EG17822A (en) 1991-03-30
EP0291512A1 (fr) 1988-11-23

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