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UY30341A1 - Proceso para la preparacion de un derivado taxano - Google Patents

Proceso para la preparacion de un derivado taxano

Info

Publication number
UY30341A1
UY30341A1 UY30341A UY30341A UY30341A1 UY 30341 A1 UY30341 A1 UY 30341A1 UY 30341 A UY30341 A UY 30341A UY 30341 A UY30341 A UY 30341A UY 30341 A1 UY30341 A1 UY 30341A1
Authority
UY
Uruguay
Prior art keywords
preparation
beta
taxan derivative
taxan
derivative
Prior art date
Application number
UY30341A
Other languages
English (en)
Inventor
Gabetta Bruno
Ciceri Daniele
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of UY30341A1 publication Critical patent/UY30341A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La invencion se refiere a un proceso mejorado para la síntesis de 13- (N-Boc-B(Beta)-isobutilserinil)-14 -B(Beta)-hidroxibacatin III-1, 14-carbonato (I), en donde la carbonacion de los grupos 1, 14-hidroxi del esqueleto de la bacatina se lleva a cabo con bis(triclorometilcarbonato y el grupo 7-hidroxi se protege con un grupo tricloroacetilo.
UY30341A 2006-05-12 2007-05-10 Proceso para la preparacion de un derivado taxano UY30341A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06009813A EP1854799B1 (en) 2006-05-12 2006-05-12 Process for the preparation of a taxane derivative

Publications (1)

Publication Number Publication Date
UY30341A1 true UY30341A1 (es) 2007-11-30

Family

ID=37708167

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30341A UY30341A1 (es) 2006-05-12 2007-05-10 Proceso para la preparacion de un derivado taxano

Country Status (19)

Country Link
EP (1) EP1854799B1 (es)
JP (1) JP5154546B2 (es)
KR (1) KR101402122B1 (es)
CN (1) CN101448839B (es)
AR (1) AR061088A1 (es)
AT (1) ATE507231T1 (es)
BR (1) BRPI0711805B8 (es)
CA (1) CA2652008C (es)
DE (1) DE602006021546D1 (es)
DK (1) DK1854799T3 (es)
ES (1) ES2363524T3 (es)
IL (1) IL195220A (es)
MX (1) MX2008014447A (es)
NO (1) NO334210B1 (es)
PE (1) PE20080398A1 (es)
RU (1) RU2434014C2 (es)
UY (1) UY30341A1 (es)
WO (1) WO2007131601A1 (es)
ZA (1) ZA200809613B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2389518T3 (es) 2008-01-18 2012-10-26 Indena S.P.A. Formas sólidas de ortataxel
CN105985353B (zh) 2015-02-11 2020-07-21 中国科学院上海药物研究所 一种化合物的a晶型及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0102407B1 (de) * 1982-09-03 1986-02-19 Wieland-Werke Ag Rippenrohr mit inneren Vorsprüngen sowie Verfahren und Vorrichtung zu dessen Herstellung
DE3440141A1 (de) * 1984-11-02 1986-05-07 Heiner Dipl.-Chem. Dr. 8000 München Eckert Verwendung von kohlensaeure-bis-trichlormethylester als proreagens fuer phosgen
KR100225535B1 (ko) * 1996-08-27 1999-10-15 정지석 파클리탁셀의 제조방법
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
IT1320107B1 (it) * 2000-11-28 2003-11-18 Indena Spa Procedimento per la preparazione di derivati tassanici.
IT1319682B1 (it) * 2000-12-06 2003-10-23 Indena Spa Procedimento di sintesi del paclitaxel.

Also Published As

Publication number Publication date
MX2008014447A (es) 2008-11-26
BRPI0711805B8 (pt) 2021-05-25
ZA200809613B (en) 2010-02-24
IL195220A0 (en) 2009-08-03
IL195220A (en) 2014-03-31
PE20080398A1 (es) 2008-05-26
ES2363524T3 (es) 2011-08-08
CN101448839A (zh) 2009-06-03
EP1854799A1 (en) 2007-11-14
WO2007131601A1 (en) 2007-11-22
RU2008144391A (ru) 2010-05-20
NO334210B1 (no) 2014-01-13
ATE507231T1 (de) 2011-05-15
BRPI0711805B1 (pt) 2020-09-24
CN101448839B (zh) 2011-09-21
CA2652008A1 (en) 2007-11-22
BRPI0711805A2 (pt) 2011-12-06
JP2009536928A (ja) 2009-10-22
EP1854799B1 (en) 2011-04-27
DE602006021546D1 (de) 2011-06-09
DK1854799T3 (da) 2011-07-18
KR101402122B1 (ko) 2014-05-30
NO20084753L (no) 2008-11-11
HK1111985A1 (en) 2008-08-22
KR20090015923A (ko) 2009-02-12
CA2652008C (en) 2014-12-30
JP5154546B2 (ja) 2013-02-27
AR061088A1 (es) 2008-08-06
RU2434014C2 (ru) 2011-11-20

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20170608