UY28372A1 - Agentes terapéuticos - Google Patents
Agentes terapéuticosInfo
- Publication number
- UY28372A1 UY28372A1 UY28372A UY28372A UY28372A1 UY 28372 A1 UY28372 A1 UY 28372A1 UY 28372 A UY28372 A UY 28372A UY 28372 A UY28372 A UY 28372A UY 28372 A1 UY28372 A1 UY 28372A1
- Authority
- UY
- Uruguay
- Prior art keywords
- salt
- ethyl
- therapeutic agents
- szal
- dyslipidemias
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- PGZGQQFVPOZCAQ-UHFFFAOYSA-N 2-[2-(4-hydroxyphenyl)ethylsulfanyl]-3-[4-[2-(4-methylsulfonyloxyphenoxy)ethyl]phenyl]propanoic acid Chemical compound C1=CC(OS(=O)(=O)C)=CC=C1OCCC(C=C1)=CC=C1CC(C(O)=O)SCCC1=CC=C(O)C=C1 PGZGQQFVPOZCAQ-UHFFFAOYSA-N 0.000 abstract 1
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 1
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- 208000001145 Metabolic Syndrome Diseases 0.000 abstract 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 abstract 1
- DKNWSYNQZKUICI-UHFFFAOYSA-N amantadine Chemical class C1C(C2)CC3CC2CC1(N)C3 DKNWSYNQZKUICI-UHFFFAOYSA-N 0.000 abstract 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 abstract 1
- 229960001231 choline Drugs 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000004885 piperazines Chemical class 0.000 abstract 1
- YBRBMKDOPFTVDT-UHFFFAOYSA-N tert-butylamine Chemical class CC(C)(C)N YBRBMKDOPFTVDT-UHFFFAOYSA-N 0.000 abstract 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical class OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Una sal de terc-butilamina, una sal de piperazina, una szal de colina, una sal de tris (hidroximetil)metilamina, una sal de lisina o una sal de adamantilamina del ácido (-)-2-((2-(4-hidroxifenil)etil)-tio)-3-(4-(2-(4-((metilsulfonil)oxi)fenoxi)etil)fenil)propanoico, procesos para su preparación, su uso en el tratamiento de trastornos clínicos incluidos trastornos lipídicos (dislipidemias) asociadas o no con resistencia a la insulina y otras manifestaciones del síndrome metabólico y composiciones farmacéuticas que las contengan.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0314130.6A GB0314130D0 (en) | 2003-06-18 | 2003-06-18 | Therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY28372A1 true UY28372A1 (es) | 2005-01-31 |
Family
ID=27636789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY28372A UY28372A1 (es) | 2003-06-18 | 2004-06-17 | Agentes terapéuticos |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20070099928A1 (es) |
| EP (1) | EP1638930A1 (es) |
| JP (1) | JP3927594B2 (es) |
| KR (1) | KR20060023165A (es) |
| CN (1) | CN1835919A (es) |
| AR (1) | AR044826A1 (es) |
| AU (1) | AU2004249483A1 (es) |
| BR (1) | BRPI0411580A (es) |
| CA (1) | CA2529544A1 (es) |
| CO (1) | CO5630026A2 (es) |
| GB (1) | GB0314130D0 (es) |
| IL (1) | IL172633A0 (es) |
| IS (1) | IS8224A (es) |
| MX (1) | MXPA05013718A (es) |
| NO (1) | NO20056006L (es) |
| RU (1) | RU2005141061A (es) |
| TW (1) | TW200503671A (es) |
| UY (1) | UY28372A1 (es) |
| WO (1) | WO2004113283A1 (es) |
| ZA (1) | ZA200510263B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0104333D0 (sv) * | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
| CN1319938C (zh) | 2002-06-20 | 2007-06-06 | 阿斯特拉曾尼卡有限公司 | 治疗胰岛素抵抗的邻位取代的苯甲酸衍生物 |
| GB0314131D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314075D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0427524D0 (en) | 2004-12-16 | 2005-01-19 | Astrazeneca Ab | Chemical process |
| GB0427701D0 (en) * | 2004-12-17 | 2005-01-19 | Astrazeneca Ab | Therapeutic agents |
| WO2008089464A1 (en) * | 2007-01-18 | 2008-07-24 | Evolva Sa | Prodrugs of substituted 1,3-dioxanes and their uses |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9801992D0 (sv) * | 1998-06-04 | 1998-06-04 | Astra Ab | New 3-aryl-2-hydroxypropionic acid derivative I |
| MA26634A1 (fr) * | 1998-06-04 | 2004-12-20 | Astra Ab | Nouveaux derives de l'acide 3-aryl propionique et analogues |
| SE0104333D0 (sv) * | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
-
2003
- 2003-06-18 GB GBGB0314130.6A patent/GB0314130D0/en not_active Ceased
-
2004
- 2004-06-16 US US10/561,222 patent/US20070099928A1/en not_active Abandoned
- 2004-06-16 WO PCT/GB2004/002576 patent/WO2004113283A1/en not_active Ceased
- 2004-06-16 AU AU2004249483A patent/AU2004249483A1/en not_active Abandoned
- 2004-06-16 BR BRPI0411580-5A patent/BRPI0411580A/pt not_active IP Right Cessation
- 2004-06-16 CA CA002529544A patent/CA2529544A1/en not_active Abandoned
- 2004-06-16 KR KR1020057024314A patent/KR20060023165A/ko not_active Withdrawn
- 2004-06-16 RU RU2005141061/04A patent/RU2005141061A/ru not_active Application Discontinuation
- 2004-06-16 JP JP2006516428A patent/JP3927594B2/ja not_active Expired - Fee Related
- 2004-06-16 MX MXPA05013718A patent/MXPA05013718A/es unknown
- 2004-06-16 CN CNA2004800231462A patent/CN1835919A/zh active Pending
- 2004-06-16 EP EP04736922A patent/EP1638930A1/en not_active Withdrawn
- 2004-06-17 UY UY28372A patent/UY28372A1/es not_active Application Discontinuation
- 2004-06-18 AR ARP040102136A patent/AR044826A1/es not_active Application Discontinuation
- 2004-06-18 TW TW093117824A patent/TW200503671A/zh unknown
-
2005
- 2005-12-15 IL IL172633A patent/IL172633A0/en unknown
- 2005-12-15 ZA ZA200510263A patent/ZA200510263B/en unknown
- 2005-12-16 NO NO20056006A patent/NO20056006L/no not_active Application Discontinuation
-
2006
- 2006-01-05 CO CO06001009A patent/CO5630026A2/es not_active Application Discontinuation
- 2006-01-10 IS IS8224A patent/IS8224A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL172633A0 (en) | 2006-04-10 |
| NO20056006L (no) | 2006-02-24 |
| GB0314130D0 (en) | 2003-07-23 |
| EP1638930A1 (en) | 2006-03-29 |
| CA2529544A1 (en) | 2004-12-29 |
| AR044826A1 (es) | 2005-10-05 |
| ZA200510263B (en) | 2007-02-28 |
| MXPA05013718A (es) | 2006-06-27 |
| US20070099928A1 (en) | 2007-05-03 |
| BRPI0411580A (pt) | 2006-08-08 |
| IS8224A (is) | 2006-01-10 |
| RU2005141061A (ru) | 2006-08-27 |
| TW200503671A (en) | 2005-02-01 |
| CO5630026A2 (es) | 2006-04-28 |
| AU2004249483A1 (en) | 2004-12-29 |
| JP3927594B2 (ja) | 2007-06-13 |
| KR20060023165A (ko) | 2006-03-13 |
| CN1835919A (zh) | 2006-09-20 |
| WO2004113283A1 (en) | 2004-12-29 |
| JP2006527749A (ja) | 2006-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20150604 |